<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
318
</numberChangedClasses>
<numberNewClasses>
99
</numberNewClasses>
<numberDeletedClasses>
143
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046872</classIRI>
<classLabel>metal ion binding</classLabel>
<deletedAxiom>&apos;metal ion binding&apos; SubClassOf &apos;cation binding&apos;</deletedAxiom>
<deletedAxiom>&apos;metal ion binding&apos; SubClassOf &apos;has input&apos; some &apos;metal cation&apos;</deletedAxiom>
<deletedAxiom>&apos;metal ion binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;metal cation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044247</classIRI>
<classLabel>cellular polysaccharide catabolic process</classLabel>
<deletedAxiom>&apos;cellular polysaccharide catabolic process&apos; SubClassOf &apos;cellular carbohydrate catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular polysaccharide catabolic process&apos; SubClassOf &apos;polysaccharide catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular polysaccharide catabolic process&apos; SubClassOf &apos;cellular polysaccharide metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001133</classIRI>
<classLabel>cardiac muscle tissue</classLabel>
<deletedAxiom>&apos;cardiac muscle tissue&apos; SubClassOf &apos;striated muscle tissue&apos;</deletedAxiom>
<newAxiom>&apos;cardiac muscle tissue&apos; SubClassOf http://purl.obolibrary.org/obo/UBERON_8600006</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044262</classIRI>
<classLabel>cellular carbohydrate metabolic process</classLabel>
<deletedAxiom>&apos;cellular carbohydrate metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular carbohydrate metabolic process&apos; SubClassOf &apos;carbohydrate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044264</classIRI>
<classLabel>cellular polysaccharide metabolic process</classLabel>
<deletedAxiom>&apos;cellular polysaccharide metabolic process&apos; SubClassOf &apos;cellular macromolecule metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular polysaccharide metabolic process&apos; SubClassOf &apos;cellular carbohydrate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular polysaccharide metabolic process&apos; SubClassOf &apos;polysaccharide metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044265</classIRI>
<classLabel>cellular macromolecule catabolic process</classLabel>
<deletedAxiom>&apos;cellular macromolecule catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular macromolecule catabolic process&apos; SubClassOf &apos;cellular macromolecule metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular macromolecule catabolic process&apos; SubClassOf &apos;macromolecule catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044260</classIRI>
<classLabel>cellular macromolecule metabolic process</classLabel>
<deletedAxiom>&apos;cellular macromolecule metabolic process&apos; SubClassOf &apos;macromolecule metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular macromolecule metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071890</classIRI>
<classLabel>bicarbonate binding</classLabel>
<deletedAxiom>&apos;bicarbonate binding&apos; SubClassOf &apos;has input&apos; some &apos;hydrogencarbonate&apos;</deletedAxiom>
<deletedAxiom>&apos;bicarbonate binding&apos; SubClassOf &apos;anion binding&apos;</deletedAxiom>
<deletedAxiom>&apos;bicarbonate binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;hydrogencarbonate&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044275</classIRI>
<classLabel>cellular carbohydrate catabolic process</classLabel>
<deletedAxiom>&apos;cellular carbohydrate catabolic process&apos; SubClassOf &apos;cellular carbohydrate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular carbohydrate catabolic process&apos; SubClassOf &apos;carbohydrate catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular carbohydrate catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002573</classIRI>
<classLabel>Schwann cell</classLabel>
<deletedAxiom>&apos;Schwann cell&apos; EquivalentTo &apos;glial cell&apos; and (&apos;part of&apos; some &apos;peripheral nervous system&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051321</classIRI>
<classLabel>meiotic cell cycle</classLabel>
<newAxiom>&apos;meiotic cell cycle&apos; SubClassOf &apos;part of&apos; some &apos;sexual reproduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051378</classIRI>
<classLabel>serotonin binding</classLabel>
<deletedAxiom>&apos;serotonin binding&apos; SubClassOf &apos;has input&apos; some &apos;serotonin(1+)&apos;</deletedAxiom>
<deletedAxiom>&apos;serotonin binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;serotonin(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;serotonin binding&apos; SubClassOf &apos;cation binding&apos;</deletedAxiom>
<deletedAxiom>&apos;serotonin binding&apos; SubClassOf &apos;amine binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019207</classIRI>
<classLabel>kinase regulator activity</classLabel>
<deletedAxiom>&apos;kinase regulator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;directly regulates&apos; some &apos;kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;kinase regulator activity&apos; SubClassOf &apos;directly regulates&apos; some &apos;kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;kinase regulator activity&apos; SubClassOf &apos;enzyme regulator activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019209</classIRI>
<classLabel>kinase activator activity</classLabel>
<deletedAxiom>&apos;kinase activator activity&apos; SubClassOf &apos;directly positively regulates&apos; some &apos;kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;kinase activator activity&apos; SubClassOf &apos;kinase regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;kinase activator activity&apos; SubClassOf &apos;enzyme activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;kinase activator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;directly positively regulates&apos; some &apos;kinase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051380</classIRI>
<classLabel>norepinephrine binding</classLabel>
<deletedAxiom>&apos;norepinephrine binding&apos; SubClassOf &apos;has input&apos; some &apos;(R)-noradrenaline(1+)&apos;</deletedAxiom>
<deletedAxiom>&apos;norepinephrine binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;(R)-noradrenaline(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;norepinephrine binding&apos; SubClassOf &apos;cation binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003723</classIRI>
<classLabel>RNA binding</classLabel>
<deletedAxiom>&apos;RNA binding&apos; SubClassOf &apos;nucleic acid binding&apos;</deletedAxiom>
<deletedAxiom>&apos;RNA binding&apos; SubClassOf &apos;has input&apos; some &apos;ribonucleic acid&apos;</deletedAxiom>
<deletedAxiom>&apos;RNA binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;ribonucleic acid&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019210</classIRI>
<classLabel>kinase inhibitor activity</classLabel>
<deletedAxiom>&apos;kinase inhibitor activity&apos; SubClassOf &apos;kinase regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;kinase inhibitor activity&apos; SubClassOf &apos;enzyme inhibitor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;kinase inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;directly negatively regulates&apos; some &apos;kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;kinase inhibitor activity&apos; SubClassOf &apos;directly negatively regulates&apos; some &apos;kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046848</classIRI>
<classLabel>hydroxyapatite binding</classLabel>
<deletedAxiom>&apos;hydroxyapatite binding&apos; SubClassOf &apos;has input&apos; some &apos;hydroxylapatite&apos;</deletedAxiom>
<deletedAxiom>&apos;hydroxyapatite binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;hydroxyapatite binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;hydroxylapatite&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070405</classIRI>
<classLabel>ammonium ion binding</classLabel>
<deletedAxiom>&apos;ammonium ion binding&apos; SubClassOf &apos;cation binding&apos;</deletedAxiom>
<deletedAxiom>&apos;ammonium ion binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;ammonium&apos;)</deletedAxiom>
<deletedAxiom>&apos;ammonium ion binding&apos; SubClassOf &apos;has input&apos; some &apos;ammonium&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015631</classIRI>
<classLabel>tubulin binding</classLabel>
<deletedAxiom>&apos;tubulin binding&apos; SubClassOf &apos;cytoskeletal protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000000</classIRI>
<classLabel>cell</classLabel>
<newAxiom>&apos;cell&apos; SubClassOf &apos;anatomical structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003687</classIRI>
<classLabel>foramen magnum</classLabel>
<deletedAxiom>&apos;foramen magnum&apos; EquivalentTo &apos;foramen of skull&apos; and (&apos;conduit for&apos; some &apos;medulla oblongata&apos;)</deletedAxiom>
<deletedAxiom>&apos;foramen magnum&apos; SubClassOf &apos;conduit for&apos; some &apos;medulla oblongata&apos;</deletedAxiom>
<newAxiom>&apos;foramen magnum&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002570 some &apos;medulla oblongata&apos;</newAxiom>
<newAxiom>&apos;foramen magnum&apos; EquivalentTo &apos;foramen of skull&apos; and (http://purl.obolibrary.org/obo/RO_0002570 some &apos;medulla oblongata&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000025</classIRI>
<classLabel>egg cell</classLabel>
<newAxiom>&apos;egg cell&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000024</classIRI>
<classLabel>oogonial cell</classLabel>
<newAxiom>&apos;oogonial cell&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000030</classIRI>
<classLabel>glioblast</classLabel>
<newAxiom>&apos;glioblast&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000037</classIRI>
<classLabel>hematopoietic stem cell</classLabel>
<deletedAxiom>&apos;hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic stem cell&apos; EquivalentTo &apos;hematopoietic cell&apos; and (&apos;capable of&apos; some &apos;hematopoietic progenitor cell differentiation&apos;) and (&apos;capable of&apos; some &apos;somatic stem cell division&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;)</deletedAxiom>
<deletedAxiom>&apos;hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;</deletedAxiom>
<newAxiom>&apos;hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;</newAxiom>
<newAxiom>&apos;hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;</newAxiom>
<newAxiom>&apos;hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 76 (mouse)&apos;</newAxiom>
<newAxiom>&apos;hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;</newAxiom>
<newAxiom>&apos;hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</newAxiom>
<newAxiom>&apos;hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;</newAxiom>
<newAxiom>&apos;hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;</newAxiom>
<newAxiom>&apos;hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;</newAxiom>
<newAxiom>&apos;hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;</newAxiom>
<newAxiom>&apos;hematopoietic stem cell&apos; EquivalentTo &apos;hematopoietic cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 76 (mouse)&apos;) and (&apos;capable of&apos; some &apos;hematopoietic progenitor cell differentiation&apos;) and (&apos;capable of&apos; some &apos;somatic stem cell division&apos;)</newAxiom>
<newAxiom>&apos;hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</newAxiom>
<newAxiom>&apos;hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;</newAxiom>
<newAxiom>&apos;hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000039</classIRI>
<classLabel>germ line cell</classLabel>
<deletedAxiom>&apos;germ line cell&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000042</classIRI>
<classLabel>neutrophilic myeloblast</classLabel>
<deletedAxiom>&apos;neutrophilic myeloblast&apos; SubClassOf &apos;protein-containing material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904526</classIRI>
<classLabel>regulation of microtubule binding</classLabel>
<deletedAxiom>&apos;regulation of microtubule binding&apos; SubClassOf &apos;regulates&apos; some &apos;microtubule binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of microtubule binding&apos; SubClassOf &apos;regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of microtubule binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;microtubule binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904527</classIRI>
<classLabel>negative regulation of microtubule binding</classLabel>
<deletedAxiom>&apos;negative regulation of microtubule binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;microtubule binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of microtubule binding&apos; SubClassOf &apos;negative regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of microtubule binding&apos; SubClassOf &apos;regulation of microtubule binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of microtubule binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;microtubule binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904528</classIRI>
<classLabel>positive regulation of microtubule binding</classLabel>
<deletedAxiom>&apos;positive regulation of microtubule binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;microtubule binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of microtubule binding&apos; SubClassOf &apos;positive regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of microtubule binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;microtubule binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of microtubule binding&apos; SubClassOf &apos;regulation of microtubule binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000066</classIRI>
<classLabel>epithelial cell</classLabel>
<deletedAxiom>&apos;epithelial cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000064</classIRI>
<classLabel>ciliated cell</classLabel>
<newAxiom>&apos;ciliated cell&apos; SubClassOf &apos;protein-containing material entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003682</classIRI>
<classLabel>chromatin binding</classLabel>
<deletedAxiom>&apos;chromatin binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;chromatin&apos;)</deletedAxiom>
<deletedAxiom>&apos;chromatin binding&apos; SubClassOf &apos;has input&apos; some &apos;chromatin&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000080</classIRI>
<classLabel>circulating cell</classLabel>
<deletedAxiom>&apos;circulating cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000081</classIRI>
<classLabel>blood cell</classLabel>
<deletedAxiom>&apos;blood cell&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003676</classIRI>
<classLabel>nucleic acid binding</classLabel>
<deletedAxiom>&apos;nucleic acid binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;nucleic acid&apos;)</deletedAxiom>
<deletedAxiom>&apos;nucleic acid binding&apos; SubClassOf &apos;organic cyclic compound binding&apos;</deletedAxiom>
<deletedAxiom>&apos;nucleic acid binding&apos; SubClassOf &apos;has input&apos; some &apos;nucleic acid&apos;</deletedAxiom>
<deletedAxiom>&apos;nucleic acid binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000094</classIRI>
<classLabel>granulocyte</classLabel>
<deletedAxiom>&apos;granulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;</deletedAxiom>
<deletedAxiom>&apos;granulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</deletedAxiom>
<deletedAxiom>&apos;granulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;granulocyte&apos; EquivalentTo &apos;myeloid leukocyte&apos; and (&apos;has_part&apos; some &apos;secretory granule&apos;) and (&apos;has plasma membrane part&apos; some &apos;integrin alpha-M&apos;) and (&apos;has plasma membrane part&apos; some &apos;carcinoembryonic antigen-related cell adhesion molecule 8&apos;) and (&apos;has plasma membrane part&apos; some &apos;urokinase plasminogen activator surface receptor&apos;) and (&apos;capable of&apos; some &apos;blood circulation&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;)</deletedAxiom>
<deletedAxiom>&apos;granulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;</deletedAxiom>
<newAxiom>&apos;granulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;</newAxiom>
<newAxiom>&apos;granulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;</newAxiom>
<newAxiom>&apos;granulocyte&apos; EquivalentTo &apos;myeloid leukocyte&apos; and (&apos;has_part&apos; some &apos;secretory granule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (&apos;has plasma membrane part&apos; some &apos;integrin alpha-M&apos;) and (&apos;has plasma membrane part&apos; some &apos;carcinoembryonic antigen-related cell adhesion molecule 8&apos;) and (&apos;has plasma membrane part&apos; some &apos;urokinase plasminogen activator surface receptor&apos;) and (&apos;capable of&apos; some &apos;blood circulation&apos;)</newAxiom>
<newAxiom>&apos;granulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</newAxiom>
<newAxiom>&apos;granulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034645</classIRI>
<classLabel>cellular macromolecule biosynthetic process</classLabel>
<deletedAxiom>&apos;cellular macromolecule biosynthetic process&apos; SubClassOf &apos;macromolecule biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular macromolecule biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular macromolecule biosynthetic process&apos; SubClassOf &apos;cellular macromolecule metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033342</classIRI>
<classLabel>negative regulation of collagen binding</classLabel>
<deletedAxiom>&apos;negative regulation of collagen binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;collagen binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of collagen binding&apos; SubClassOf &apos;regulation of collagen binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of collagen binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;collagen binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of collagen binding&apos; SubClassOf &apos;negative regulation of binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033341</classIRI>
<classLabel>regulation of collagen binding</classLabel>
<deletedAxiom>&apos;regulation of collagen binding&apos; SubClassOf &apos;regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of collagen binding&apos; SubClassOf &apos;regulates&apos; some &apos;collagen binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of collagen binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;collagen binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033343</classIRI>
<classLabel>positive regulation of collagen binding</classLabel>
<deletedAxiom>&apos;positive regulation of collagen binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;collagen binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of collagen binding&apos; SubClassOf &apos;regulation of collagen binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of collagen binding&apos; SubClassOf &apos;positive regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of collagen binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;collagen binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032052</classIRI>
<classLabel>bile acid binding</classLabel>
<deletedAxiom>&apos;bile acid binding&apos; SubClassOf &apos;has input&apos; some &apos;bile acid anion&apos;</deletedAxiom>
<deletedAxiom>&apos;bile acid binding&apos; SubClassOf &apos;monocarboxylic acid binding&apos;</deletedAxiom>
<deletedAxiom>&apos;bile acid binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;bile acid anion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004857</classIRI>
<classLabel>enzyme inhibitor activity</classLabel>
<deletedAxiom>&apos;enzyme inhibitor activity&apos; SubClassOf &apos;enzyme regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;enzyme inhibitor activity&apos; SubClassOf &apos;directly negatively regulates&apos; some &apos;catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;enzyme inhibitor activity&apos; SubClassOf &apos;molecular function inhibitor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;enzyme inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;directly negatively regulates&apos; some &apos;catalytic activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032091</classIRI>
<classLabel>negative regulation of protein binding</classLabel>
<deletedAxiom>&apos;negative regulation of protein binding&apos; SubClassOf &apos;negative regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;protein binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein binding&apos; SubClassOf &apos;regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032092</classIRI>
<classLabel>positive regulation of protein binding</classLabel>
<deletedAxiom>&apos;positive regulation of protein binding&apos; SubClassOf &apos;regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;protein binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein binding&apos; SubClassOf &apos;positive regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000149</classIRI>
<classLabel>visual pigment cell</classLabel>
<newAxiom>&apos;visual pigment cell&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000148</classIRI>
<classLabel>melanocyte</classLabel>
<deletedAxiom>&apos;melanocyte&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000152</classIRI>
<classLabel>exocrine cell</classLabel>
<newAxiom>&apos;exocrine cell&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000151</classIRI>
<classLabel>secretory cell</classLabel>
<deletedAxiom>&apos;secretory cell&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000163</classIRI>
<classLabel>endocrine cell</classLabel>
<deletedAxiom>&apos;endocrine cell&apos; SubClassOf &apos;part of&apos; some &apos;endocrine gland&apos;</deletedAxiom>
<deletedAxiom>&apos;endocrine cell&apos; EquivalentTo &apos;secretory cell&apos; and (&apos;capable of&apos; some &apos;endocrine hormone secretion&apos;)</deletedAxiom>
<deletedAxiom>&apos;endocrine cell&apos; SubClassOf &apos;capable of&apos; some &apos;endocrine hormone secretion&apos;</deletedAxiom>
<newAxiom>&apos;endocrine cell&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
<newAxiom>&apos;endocrine cell&apos; SubClassOf &apos;capable of&apos; some 
(&apos;hormone secretion&apos; and (&apos;has target end location&apos; some &apos;circulatory system&apos;))</newAxiom>
<newAxiom>&apos;endocrine cell&apos; SubClassOf &apos;part of&apos; some &apos;endocrine system&apos;</newAxiom>
<newAxiom>&apos;endocrine cell&apos; EquivalentTo &apos;native cell&apos; and (&apos;capable of&apos; some 
(&apos;hormone secretion&apos; and (&apos;has target end location&apos; some &apos;circulatory system&apos;)))</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000169</classIRI>
<classLabel>type B pancreatic cell</classLabel>
<deletedAxiom>&apos;type B pancreatic cell&apos; SubClassOf &apos;enteroendocrine cell&apos;</deletedAxiom>
<deletedAxiom>&apos;type B pancreatic cell&apos; SubClassOf &apos;epithelial cell of pancreas&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000174</classIRI>
<classLabel>steroid hormone secreting cell</classLabel>
<deletedAxiom>&apos;steroid hormone secreting cell&apos; SubClassOf &apos;endocrine cell&apos;</deletedAxiom>
<newAxiom>&apos;steroid hormone secreting cell&apos; SubClassOf &apos;secretory cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000173</classIRI>
<classLabel>pancreatic D cell</classLabel>
<deletedAxiom>&apos;pancreatic D cell&apos; SubClassOf &apos;epithelial cell of pancreas&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000171</classIRI>
<classLabel>pancreatic A cell</classLabel>
<deletedAxiom>&apos;pancreatic A cell&apos; SubClassOf &apos;epithelial cell of pancreas&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000187</classIRI>
<classLabel>muscle cell</classLabel>
<deletedAxiom>&apos;muscle cell&apos; SubClassOf &apos;animal cell&apos;</deletedAxiom>
<deletedAxiom>&apos;muscle cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000188</classIRI>
<classLabel>cell of skeletal muscle</classLabel>
<deletedAxiom>&apos;cell of skeletal muscle&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000182</classIRI>
<classLabel>hepatocyte</classLabel>
<deletedAxiom>&apos;hepatocyte&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000197</classIRI>
<classLabel>sensory receptor cell</classLabel>
<deletedAxiom>&apos;sensory receptor cell&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051100</classIRI>
<classLabel>negative regulation of binding</classLabel>
<deletedAxiom>&apos;negative regulation of binding&apos; SubClassOf &apos;regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of binding&apos; SubClassOf &apos;negative regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034637</classIRI>
<classLabel>cellular carbohydrate biosynthetic process</classLabel>
<deletedAxiom>&apos;cellular carbohydrate biosynthetic process&apos; SubClassOf &apos;carbohydrate biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular carbohydrate biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular carbohydrate biosynthetic process&apos; SubClassOf &apos;cellular carbohydrate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010675</classIRI>
<classLabel>regulation of cellular carbohydrate metabolic process</classLabel>
<deletedAxiom>&apos;regulation of cellular carbohydrate metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular carbohydrate metabolic process&apos; SubClassOf &apos;regulates&apos; some &apos;cellular carbohydrate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular carbohydrate metabolic process&apos; SubClassOf &apos;regulation of carbohydrate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular carbohydrate metabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;cellular carbohydrate metabolic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010676</classIRI>
<classLabel>positive regulation of cellular carbohydrate metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of cellular carbohydrate metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular carbohydrate metabolic process&apos; SubClassOf &apos;positively regulates&apos; some &apos;cellular carbohydrate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular carbohydrate metabolic process&apos; SubClassOf &apos;positive regulation of carbohydrate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular carbohydrate metabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;cellular carbohydrate metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular carbohydrate metabolic process&apos; SubClassOf &apos;regulation of cellular carbohydrate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010677</classIRI>
<classLabel>negative regulation of cellular carbohydrate metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of cellular carbohydrate metabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;cellular carbohydrate metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular carbohydrate metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular carbohydrate metabolic process&apos; SubClassOf &apos;negatively regulates&apos; some &apos;cellular carbohydrate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular carbohydrate metabolic process&apos; SubClassOf &apos;negative regulation of carbohydrate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular carbohydrate metabolic process&apos; SubClassOf &apos;regulation of cellular carbohydrate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033212</classIRI>
<classLabel>iron import into cell</classLabel>
<deletedAxiom>&apos;iron import into cell&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
<newAxiom>&apos;iron import into cell&apos; SubClassOf &apos;has target start location&apos; some &apos;extracellular region&apos;</newAxiom>
<newAxiom>&apos;iron import into cell&apos; SubClassOf &apos;has target end location&apos; some &apos;intracellular anatomical structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035855</classIRI>
<classLabel>megakaryocyte development</classLabel>
<deletedAxiom>&apos;megakaryocyte development&apos; SubClassOf &apos;bone cell development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033218</classIRI>
<classLabel>amide binding</classLabel>
<deletedAxiom>&apos;amide binding&apos; SubClassOf &apos;has input&apos; some &apos;amide&apos;</deletedAxiom>
<deletedAxiom>&apos;amide binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;amide binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;amide&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008289</classIRI>
<classLabel>lipid binding</classLabel>
<deletedAxiom>&apos;lipid binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;lipid binding&apos; SubClassOf &apos;has input&apos; some &apos;lipid&apos;</deletedAxiom>
<deletedAxiom>&apos;lipid binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;lipid&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033293</classIRI>
<classLabel>monocarboxylic acid binding</classLabel>
<deletedAxiom>&apos;monocarboxylic acid binding&apos; SubClassOf &apos;carboxylic acid binding&apos;</deletedAxiom>
<deletedAxiom>&apos;monocarboxylic acid binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;monocarboxylic acid anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;monocarboxylic acid binding&apos; SubClassOf &apos;has input&apos; some &apos;monocarboxylic acid anion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000219</classIRI>
<classLabel>motile cell</classLabel>
<deletedAxiom>&apos;motile cell&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000223</classIRI>
<classLabel>endodermal cell</classLabel>
<deletedAxiom>&apos;endodermal cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000222</classIRI>
<classLabel>mesodermal cell</classLabel>
<deletedAxiom>&apos;mesodermal cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000221</classIRI>
<classLabel>ectodermal cell</classLabel>
<deletedAxiom>&apos;ectodermal cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045296</classIRI>
<classLabel>cadherin binding</classLabel>
<deletedAxiom>&apos;cadherin binding&apos; SubClassOf &apos;cell adhesion molecule binding&apos;</deletedAxiom>
<deletedAxiom>&apos;cadherin binding&apos; SubClassOf &apos;has input&apos; some &apos;cadherin&apos;</deletedAxiom>
<deletedAxiom>&apos;cadherin binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;cadherin&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000234</classIRI>
<classLabel>phagocyte</classLabel>
<newAxiom>&apos;phagocyte&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000232</classIRI>
<classLabel>erythrocyte</classLabel>
<deletedAxiom>&apos;erythrocyte&apos; EquivalentTo &apos;erythroid lineage cell&apos; and (&apos;bearer of&apos; some &apos;biconcave&apos;) and (&apos;capable of&apos; some &apos;blood circulation&apos;) and (&apos;capable of&apos; some &apos;oxygen transport&apos;) and (&apos;lacks_part&apos; some &apos;ribosome&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;transferrin receptor protein 1&apos;)</deletedAxiom>
<deletedAxiom>&apos;erythrocyte&apos; SubClassOf &apos;lacks_part&apos; some &apos;ribosome&apos;</deletedAxiom>
<deletedAxiom>&apos;erythrocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;transferrin receptor protein 1&apos;</deletedAxiom>
<newAxiom>&apos;erythrocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;transferrin receptor protein 1&apos;</newAxiom>
<newAxiom>&apos;erythrocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030045 some &apos;ribosome&apos;</newAxiom>
<newAxiom>&apos;erythrocyte&apos; EquivalentTo &apos;erythroid lineage cell&apos; and (http://purl.obolibrary.org/obo/CL_4030045 some &apos;ribosome&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;transferrin receptor protein 1&apos;) and (&apos;bearer of&apos; some &apos;biconcave&apos;) and (&apos;capable of&apos; some &apos;blood circulation&apos;) and (&apos;capable of&apos; some &apos;oxygen transport&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002054</classIRI>
<classLabel>nucleobase binding</classLabel>
<deletedAxiom>&apos;nucleobase binding&apos; SubClassOf &apos;small molecule binding&apos;</deletedAxiom>
<deletedAxiom>&apos;nucleobase binding&apos; SubClassOf &apos;has input&apos; some &apos;nucleobase&apos;</deletedAxiom>
<deletedAxiom>&apos;nucleobase binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
<deletedAxiom>&apos;nucleobase binding&apos; SubClassOf &apos;organic cyclic compound binding&apos;</deletedAxiom>
<deletedAxiom>&apos;nucleobase binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;nucleobase&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904793</classIRI>
<classLabel>regulation of euchromatin binding</classLabel>
<deletedAxiom>&apos;regulation of euchromatin binding&apos; SubClassOf &apos;regulates&apos; some &apos;euchromatin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of euchromatin binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;euchromatin binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of euchromatin binding&apos; SubClassOf &apos;regulation of chromatin binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904794</classIRI>
<classLabel>negative regulation of euchromatin binding</classLabel>
<deletedAxiom>&apos;negative regulation of euchromatin binding&apos; SubClassOf &apos;negative regulation of chromatin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of euchromatin binding&apos; SubClassOf &apos;regulation of euchromatin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of euchromatin binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;euchromatin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of euchromatin binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;euchromatin binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904795</classIRI>
<classLabel>positive regulation of euchromatin binding</classLabel>
<deletedAxiom>&apos;positive regulation of euchromatin binding&apos; SubClassOf &apos;regulation of euchromatin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of euchromatin binding&apos; SubClassOf &apos;positive regulation of chromatin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of euchromatin binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;euchromatin binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of euchromatin binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;euchromatin binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051098</classIRI>
<classLabel>regulation of binding</classLabel>
<deletedAxiom>&apos;regulation of binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of binding&apos; SubClassOf &apos;regulates&apos; some &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of binding&apos; SubClassOf &apos;regulation of molecular function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051099</classIRI>
<classLabel>positive regulation of binding</classLabel>
<deletedAxiom>&apos;positive regulation of binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of binding&apos; SubClassOf &apos;regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of binding&apos; SubClassOf &apos;positive regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051059</classIRI>
<classLabel>NF-kappaB binding</classLabel>
<deletedAxiom>&apos;NF-kappaB binding&apos; SubClassOf &apos;RNA polymerase II-specific DNA-binding transcription factor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;NF-kappaB binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;transcription factor NF-kappa-B subunit&apos;)</deletedAxiom>
<deletedAxiom>&apos;NF-kappaB binding&apos; SubClassOf &apos;has input&apos; some &apos;transcription factor NF-kappa-B subunit&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010559</classIRI>
<classLabel>regulation of glycoprotein biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of glycoprotein biosynthetic process&apos; SubClassOf &apos;regulation of cellular macromolecule biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of glycoprotein biosynthetic process&apos; SubClassOf &apos;regulation of macromolecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010560</classIRI>
<classLabel>positive regulation of glycoprotein biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of glycoprotein biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010561</classIRI>
<classLabel>negative regulation of glycoprotein biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of glycoprotein biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular macromolecule biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of glycoprotein biosynthetic process&apos; SubClassOf &apos;negative regulation of macromolecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008134</classIRI>
<classLabel>transcription factor binding</classLabel>
<deletedAxiom>&apos;transcription factor binding&apos; SubClassOf &apos;protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0014892</classIRI>
<classLabel>skeletal muscle organ</classLabel>
<deletedAxiom>&apos;skeletal muscle organ&apos; EquivalentTo &apos;muscle organ&apos; and (&apos;develops from&apos; some &apos;myotome&apos;) and (&apos;surrounded by&apos; some &apos;epimysium&apos;) and (&apos;composed primarily of&apos; some &apos;skeletal muscle tissue&apos;) and (&apos;synapsed by&apos; some &apos;motor neuron&apos;)</deletedAxiom>
<deletedAxiom>&apos;skeletal muscle organ&apos; SubClassOf &apos;synapsed by&apos; some &apos;motor neuron&apos;</deletedAxiom>
<newAxiom>&apos;skeletal muscle organ&apos; EquivalentTo &apos;muscle organ&apos; and (http://purl.obolibrary.org/obo/RO_0002103 some &apos;motor neuron&apos;) and (&apos;develops from&apos; some &apos;myotome&apos;) and (&apos;surrounded by&apos; some &apos;epimysium&apos;) and (&apos;composed primarily of&apos; some &apos;skeletal muscle tissue&apos;)</newAxiom>
<newAxiom>&apos;skeletal muscle organ&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002103 some &apos;motor neuron&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005977</classIRI>
<classLabel>glycogen metabolic process</classLabel>
<deletedAxiom>&apos;glycogen metabolic process&apos; SubClassOf &apos;cellular glucan metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;glycogen metabolic process&apos; SubClassOf &apos;glucan metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005980</classIRI>
<classLabel>glycogen catabolic process</classLabel>
<deletedAxiom>&apos;glycogen catabolic process&apos; SubClassOf &apos;cellular polysaccharide catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005981</classIRI>
<classLabel>regulation of glycogen catabolic process</classLabel>
<deletedAxiom>&apos;regulation of glycogen catabolic process&apos; SubClassOf &apos;regulation of cellular carbohydrate catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of glycogen catabolic process&apos; SubClassOf &apos;regulation of carbohydrate catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045182</classIRI>
<classLabel>translation regulator activity</classLabel>
<deletedAxiom>&apos;translation regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;part of&apos; some &apos;regulation of translation&apos;)</deletedAxiom>
<deletedAxiom>&apos;translation regulator activity&apos; SubClassOf &apos;molecular_function&apos;</deletedAxiom>
<deletedAxiom>&apos;translation regulator activity&apos; SubClassOf &apos;part of&apos; some &apos;regulation of translation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070051</classIRI>
<classLabel>fibrinogen binding</classLabel>
<deletedAxiom>&apos;fibrinogen binding&apos; SubClassOf &apos;has input&apos; some &apos;fibrinogen complex&apos;</deletedAxiom>
<deletedAxiom>&apos;fibrinogen binding&apos; SubClassOf &apos;protein-containing complex binding&apos;</deletedAxiom>
<deletedAxiom>&apos;fibrinogen binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;fibrinogen complex&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016597</classIRI>
<classLabel>amino acid binding</classLabel>
<deletedAxiom>&apos;amino acid binding&apos; SubClassOf &apos;has input&apos; some &apos;amino acid&apos;</deletedAxiom>
<deletedAxiom>&apos;amino acid binding&apos; SubClassOf &apos;organic acid binding&apos;</deletedAxiom>
<deletedAxiom>&apos;amino acid binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;amino acid&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016595</classIRI>
<classLabel>glutamate binding</classLabel>
<deletedAxiom>&apos;glutamate binding&apos; SubClassOf &apos;carboxylic acid binding&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamate binding&apos; SubClassOf &apos;has input&apos; some &apos;glutamate(1-)&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamate binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;glutamate(1-)&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0007009</classIRI>
<classLabel>prechondroblast</classLabel>
<newAxiom>&apos;prechondroblast&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008017</classIRI>
<classLabel>microtubule binding</classLabel>
<deletedAxiom>&apos;microtubule binding&apos; SubClassOf &apos;has input&apos; some &apos;microtubule&apos;</deletedAxiom>
<deletedAxiom>&apos;microtubule binding&apos; SubClassOf &apos;tubulin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;microtubule binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;microtubule&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0019001</classIRI>
<classLabel>tracheobronchial serous cell</classLabel>
<newAxiom>&apos;tracheobronchial serous cell&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008047</classIRI>
<classLabel>enzyme activator activity</classLabel>
<deletedAxiom>&apos;enzyme activator activity&apos; SubClassOf &apos;directly positively regulates&apos; some &apos;catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;enzyme activator activity&apos; SubClassOf &apos;molecular function activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;enzyme activator activity&apos; SubClassOf &apos;enzyme regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;enzyme activator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;directly positively regulates&apos; some &apos;catalytic activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090493</classIRI>
<classLabel>catecholamine uptake</classLabel>
<deletedAxiom>&apos;catecholamine uptake&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
<newAxiom>&apos;catecholamine uptake&apos; SubClassOf &apos;has target end location&apos; some &apos;intracellular anatomical structure&apos;</newAxiom>
<newAxiom>&apos;catecholamine uptake&apos; SubClassOf &apos;has target start location&apos; some &apos;extracellular region&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008092</classIRI>
<classLabel>cytoskeletal protein binding</classLabel>
<deletedAxiom>&apos;cytoskeletal protein binding&apos; SubClassOf &apos;protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001069</classIRI>
<classLabel>glycogen binding</classLabel>
<deletedAxiom>&apos;glycogen binding&apos; SubClassOf &apos;has input&apos; some &apos;glycogen&apos;</deletedAxiom>
<deletedAxiom>&apos;glycogen binding&apos; SubClassOf &apos;polysaccharide binding&apos;</deletedAxiom>
<deletedAxiom>&apos;glycogen binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;glycogen&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002275</classIRI>
<classLabel>pancreatic PP cell</classLabel>
<deletedAxiom>&apos;pancreatic PP cell&apos; SubClassOf &apos;epithelial cell of pancreas&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0018321</classIRI>
<classLabel>foramen for glossopharyngeal nerve</classLabel>
<deletedAxiom>&apos;foramen for glossopharyngeal nerve&apos; EquivalentTo &apos;foramen of skull&apos; and (&apos;conduit for&apos; some &apos;glossopharyngeal nerve&apos;)</deletedAxiom>
<deletedAxiom>&apos;foramen for glossopharyngeal nerve&apos; SubClassOf &apos;conduit for&apos; some &apos;glossopharyngeal nerve&apos;</deletedAxiom>
<newAxiom>&apos;foramen for glossopharyngeal nerve&apos; EquivalentTo &apos;foramen of skull&apos; and (http://purl.obolibrary.org/obo/RO_0002570 some &apos;glossopharyngeal nerve&apos;)</newAxiom>
<newAxiom>&apos;foramen for glossopharyngeal nerve&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002570 some &apos;glossopharyngeal nerve&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009250</classIRI>
<classLabel>glucan biosynthetic process</classLabel>
<deletedAxiom>&apos;glucan biosynthetic process&apos; SubClassOf &apos;cellular glucan metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;glucan biosynthetic process&apos; SubClassOf &apos;cellular polysaccharide biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;glucan biosynthetic process&apos; SubClassOf &apos;glucan metabolic process&apos;</newAxiom>
<newAxiom>&apos;glucan biosynthetic process&apos; SubClassOf &apos;polysaccharide biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035563</classIRI>
<classLabel>positive regulation of chromatin binding</classLabel>
<deletedAxiom>&apos;positive regulation of chromatin binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;chromatin binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chromatin binding&apos; SubClassOf &apos;positive regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chromatin binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;chromatin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chromatin binding&apos; SubClassOf &apos;regulation of chromatin binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035561</classIRI>
<classLabel>regulation of chromatin binding</classLabel>
<deletedAxiom>&apos;regulation of chromatin binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;chromatin binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of chromatin binding&apos; SubClassOf &apos;regulates&apos; some &apos;chromatin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of chromatin binding&apos; SubClassOf &apos;regulation of binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035562</classIRI>
<classLabel>negative regulation of chromatin binding</classLabel>
<deletedAxiom>&apos;negative regulation of chromatin binding&apos; SubClassOf &apos;regulation of chromatin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chromatin binding&apos; SubClassOf &apos;negative regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chromatin binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;chromatin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chromatin binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;chromatin binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008814</classIRI>
<classLabel>pharyngeal arch system</classLabel>
<deletedAxiom>&apos;pharyngeal arch system&apos; SubClassOf &apos;anatomical cluster&apos;</deletedAxiom>
<newAxiom>&apos;pharyngeal arch system&apos; SubClassOf &apos;multi organ part structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060548</classIRI>
<classLabel>negative regulation of cell death</classLabel>
<deletedAxiom>&apos;negative regulation of cell death&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;cell death&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cell death&apos; SubClassOf &apos;regulation of cell death&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cell death&apos; SubClassOf &apos;negative regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cell death&apos; SubClassOf &apos;negatively regulates&apos; some &apos;cell death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060586</classIRI>
<classLabel>multicellular organismal-level iron ion homeostasis</classLabel>
<deletedAxiom>&apos;multicellular organismal-level iron ion homeostasis&apos; SubClassOf &apos;iron ion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;multicellular organismal-level iron ion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</newAxiom>
<newAxiom>&apos;multicellular organismal-level iron ion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;iron cation&apos;</newAxiom>
<newAxiom>&apos;multicellular organismal-level iron ion homeostasis&apos; SubClassOf &apos;monoatomic cation homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901214</classIRI>
<classLabel>regulation of neuron death</classLabel>
<deletedAxiom>&apos;regulation of neuron death&apos; SubClassOf &apos;regulation of cell death&apos;</deletedAxiom>
<newAxiom>&apos;regulation of neuron death&apos; SubClassOf &apos;regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901215</classIRI>
<classLabel>negative regulation of neuron death</classLabel>
<deletedAxiom>&apos;negative regulation of neuron death&apos; SubClassOf &apos;negative regulation of cell death&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of neuron death&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901216</classIRI>
<classLabel>positive regulation of neuron death</classLabel>
<deletedAxiom>&apos;positive regulation of neuron death&apos; SubClassOf &apos;positive regulation of cell death&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of neuron death&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000058</classIRI>
<classLabel>duct</classLabel>
<deletedAxiom>&apos;duct&apos; SubClassOf &apos;conduit for&apos; some &apos;organism substance&apos;</deletedAxiom>
<newAxiom>&apos;duct&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002570 some &apos;organism substance&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002319</classIRI>
<classLabel>neural cell</classLabel>
<deletedAxiom>&apos;neural cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
<deletedAxiom>&apos;neural cell&apos; SubClassOf &apos;animal cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002320</classIRI>
<classLabel>connective tissue cell</classLabel>
<deletedAxiom>&apos;connective tissue cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
<deletedAxiom>&apos;connective tissue cell&apos; SubClassOf &apos;animal cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0001008</classIRI>
<classLabel>Kit and Sca1-positive hematopoietic stem cell</classLabel>
<deletedAxiom>&apos;Kit and Sca1-positive hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD48 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit and Sca1-positive hematopoietic stem cell&apos; EquivalentTo &apos;hematopoietic stem cell&apos; and (&apos;has plasma membrane part&apos; some &apos;SLAM family member 1&apos;) and (&apos;has plasma membrane part&apos; some &apos;mast/stem cell growth factor receptor&apos;) and (&apos;has plasma membrane part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RABC&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD48 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;natural killer cell receptor 2B4&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;killer cell lectin-like receptor subfamily B member 1C&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;)</deletedAxiom>
<deletedAxiom>&apos;Kit and Sca1-positive hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RABC&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit and Sca1-positive hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;natural killer cell receptor 2B4&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit and Sca1-positive hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit and Sca1-positive hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;killer cell lectin-like receptor subfamily B member 1C&apos;</deletedAxiom>
<newAxiom>&apos;Kit and Sca1-positive hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;killer cell lectin-like receptor subfamily B member 1C&apos;</newAxiom>
<newAxiom>&apos;Kit and Sca1-positive hematopoietic stem cell&apos; EquivalentTo &apos;hematopoietic stem cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RABC&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD48 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;natural killer cell receptor 2B4&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;killer cell lectin-like receptor subfamily B member 1C&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 76 (mouse)&apos;) and (&apos;has plasma membrane part&apos; some &apos;SLAM family member 1&apos;) and (&apos;has plasma membrane part&apos; some &apos;mast/stem cell growth factor receptor&apos;) and (&apos;has plasma membrane part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;)</newAxiom>
<newAxiom>&apos;Kit and Sca1-positive hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;natural killer cell receptor 2B4&apos;</newAxiom>
<newAxiom>&apos;Kit and Sca1-positive hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD48 molecule&apos;</newAxiom>
<newAxiom>&apos;Kit and Sca1-positive hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;</newAxiom>
<newAxiom>&apos;Kit and Sca1-positive hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RABC&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000086</classIRI>
<classLabel>zona pellucida</classLabel>
<deletedAxiom>&apos;zona pellucida&apos; SubClassOf &apos;acellular anatomical structure&apos;</deletedAxiom>
<newAxiom>&apos;zona pellucida&apos; SubClassOf &apos;acellular membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0001027</classIRI>
<classLabel>CD7-negative lymphoid progenitor cell</classLabel>
<deletedAxiom>&apos;CD7-negative lymphoid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;</deletedAxiom>
<deletedAxiom>&apos;CD7-negative lymphoid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD7 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;CD7-negative lymphoid progenitor cell&apos; EquivalentTo &apos;common lymphoid progenitor&apos; and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD7 molecule&apos;)</deletedAxiom>
<newAxiom>&apos;CD7-negative lymphoid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD7 molecule&apos;</newAxiom>
<newAxiom>&apos;CD7-negative lymphoid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;</newAxiom>
<newAxiom>&apos;CD7-negative lymphoid progenitor cell&apos; EquivalentTo &apos;common lymphoid progenitor&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD7 molecule&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002351</classIRI>
<classLabel>progenitor cell of endocrine pancreas</classLabel>
<newAxiom>&apos;progenitor cell of endocrine pancreas&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0001026</classIRI>
<classLabel>CD34-positive, CD38-positive common myeloid progenitor</classLabel>
<deletedAxiom>&apos;CD34-positive, CD38-positive common myeloid progenitor&apos; EquivalentTo &apos;common myeloid progenitor, CD34-positive&apos; and (&apos;has plasma membrane part&apos; some &apos;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1&apos;) and (&apos;has low plasma membrane amount&apos; some &apos;interleukin-3 receptor class 2 alpha chain&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD7 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-5 receptor subunit alpha&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;neprilysin&apos;)</deletedAxiom>
<deletedAxiom>&apos;CD34-positive, CD38-positive common myeloid progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-5 receptor subunit alpha&apos;</deletedAxiom>
<deletedAxiom>&apos;CD34-positive, CD38-positive common myeloid progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;neprilysin&apos;</deletedAxiom>
<deletedAxiom>&apos;CD34-positive, CD38-positive common myeloid progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD7 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;CD34-positive, CD38-positive common myeloid progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;</deletedAxiom>
<newAxiom>&apos;CD34-positive, CD38-positive common myeloid progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD7 molecule&apos;</newAxiom>
<newAxiom>&apos;CD34-positive, CD38-positive common myeloid progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;neprilysin&apos;</newAxiom>
<newAxiom>&apos;CD34-positive, CD38-positive common myeloid progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;</newAxiom>
<newAxiom>&apos;CD34-positive, CD38-positive common myeloid progenitor&apos; EquivalentTo &apos;common myeloid progenitor, CD34-positive&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD7 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-5 receptor subunit alpha&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;neprilysin&apos;) and (&apos;has plasma membrane part&apos; some &apos;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1&apos;) and (&apos;has low plasma membrane amount&apos; some &apos;interleukin-3 receptor class 2 alpha chain&apos;)</newAxiom>
<newAxiom>&apos;CD34-positive, CD38-positive common myeloid progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-5 receptor subunit alpha&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0001024</classIRI>
<classLabel>CD34-positive, CD38-negative hematopoietic stem cell</classLabel>
<deletedAxiom>&apos;CD34-positive, CD38-negative hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD33 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;CD34-positive, CD38-negative hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;low affinity immunoglobulin gamma Fc region receptor III&apos;</deletedAxiom>
<deletedAxiom>&apos;CD34-positive, CD38-negative hematopoietic stem cell&apos; EquivalentTo &apos;hematopoietic stem cell&apos; and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;) and (&apos;has plasma membrane part&apos; some &apos;prominin-1&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD59-like glycoprotein&apos;) and (&apos;has plasma membrane part&apos; some &apos;Thy-1 membrane glycoprotein&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;low affinity immunoglobulin gamma Fc region receptor III&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD33 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;transferrin receptor protein 1&apos;)</deletedAxiom>
<deletedAxiom>&apos;CD34-positive, CD38-negative hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;transferrin receptor protein 1&apos;</deletedAxiom>
<deletedAxiom>&apos;CD34-positive, CD38-negative hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1&apos;</deletedAxiom>
<newAxiom>&apos;CD34-positive, CD38-negative hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;low affinity immunoglobulin gamma Fc region receptor III&apos;</newAxiom>
<newAxiom>&apos;CD34-positive, CD38-negative hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD33 molecule&apos;</newAxiom>
<newAxiom>&apos;CD34-positive, CD38-negative hematopoietic stem cell&apos; EquivalentTo &apos;hematopoietic stem cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;low affinity immunoglobulin gamma Fc region receptor III&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD33 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;transferrin receptor protein 1&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;) and (&apos;has plasma membrane part&apos; some &apos;prominin-1&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD59-like glycoprotein&apos;) and (&apos;has plasma membrane part&apos; some &apos;Thy-1 membrane glycoprotein&apos;)</newAxiom>
<newAxiom>&apos;CD34-positive, CD38-negative hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;transferrin receptor protein 1&apos;</newAxiom>
<newAxiom>&apos;CD34-positive, CD38-negative hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0001029</classIRI>
<classLabel>common dendritic progenitor</classLabel>
<deletedAxiom>&apos;common dendritic progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;common dendritic progenitor&apos; EquivalentTo &apos;hematopoietic lineage restricted progenitor cell&apos; and (&apos;has plasma membrane part&apos; some &apos;receptor-type tyrosine-protein kinase FLT3&apos;) and (&apos;has plasma membrane part&apos; some &apos;macrophage colony-stimulating factor 1 receptor&apos;) and (&apos;has low plasma membrane amount&apos; some &apos;mast/stem cell growth factor receptor&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;)</deletedAxiom>
<deletedAxiom>&apos;common dendritic progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</deletedAxiom>
<deletedAxiom>&apos;common dendritic progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;</deletedAxiom>
<deletedAxiom>&apos;common dendritic progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;</deletedAxiom>
<deletedAxiom>&apos;common dendritic progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;common dendritic progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;common dendritic progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</deletedAxiom>
<deletedAxiom>&apos;common dendritic progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;</deletedAxiom>
<deletedAxiom>&apos;common dendritic progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;</deletedAxiom>
<deletedAxiom>&apos;common dendritic progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;common dendritic progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;</deletedAxiom>
<deletedAxiom>&apos;common dendritic progenitor&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;</deletedAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;</newAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;</newAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;</newAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</newAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;</newAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; EquivalentTo &apos;hematopoietic lineage restricted progenitor cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 76 (mouse)&apos;) and (&apos;has plasma membrane part&apos; some &apos;receptor-type tyrosine-protein kinase FLT3&apos;) and (&apos;has plasma membrane part&apos; some &apos;macrophage colony-stimulating factor 1 receptor&apos;) and (&apos;has low plasma membrane amount&apos; some &apos;mast/stem cell growth factor receptor&apos;)</newAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</newAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 76 (mouse)&apos;</newAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;</newAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;</newAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; SubClassOf &apos;protein-containing material entity&apos;</newAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;</newAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;</newAxiom>
<newAxiom>&apos;common dendritic progenitor&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0001028</classIRI>
<classLabel>CD7-positive lymphoid progenitor cell</classLabel>
<deletedAxiom>&apos;CD7-positive lymphoid progenitor cell&apos; EquivalentTo &apos;common lymphoid progenitor&apos; and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD7 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;)</deletedAxiom>
<deletedAxiom>&apos;CD7-positive lymphoid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;</deletedAxiom>
<newAxiom>&apos;CD7-positive lymphoid progenitor cell&apos; EquivalentTo &apos;common lymphoid progenitor&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD7 molecule&apos;)</newAxiom>
<newAxiom>&apos;CD7-positive lymphoid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0001035</classIRI>
<classLabel>bone cell</classLabel>
<deletedAxiom>&apos;bone cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002371</classIRI>
<classLabel>somatic cell</classLabel>
<deletedAxiom>&apos;somatic cell&apos; SubClassOf &apos;native cell&apos;</deletedAxiom>
<newAxiom>&apos;somatic cell&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0001054</classIRI>
<classLabel>CD14-positive monocyte</classLabel>
<deletedAxiom>&apos;CD14-positive monocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;</deletedAxiom>
<deletedAxiom>&apos;CD14-positive monocyte&apos; EquivalentTo &apos;monocyte&apos; and (&apos;has plasma membrane part&apos; some &apos;CD14 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;)</deletedAxiom>
<deletedAxiom>&apos;CD14-positive monocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</deletedAxiom>
<deletedAxiom>&apos;CD14-positive monocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;</deletedAxiom>
<newAxiom>&apos;CD14-positive monocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;</newAxiom>
<newAxiom>&apos;CD14-positive monocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</newAxiom>
<newAxiom>&apos;CD14-positive monocyte&apos; EquivalentTo &apos;monocyte&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD14 molecule&apos;)</newAxiom>
<newAxiom>&apos;CD14-positive monocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0001066</classIRI>
<classLabel>erythroid progenitor cell, mammalian</classLabel>
<deletedAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroid progenitor cell, mammalian&apos; EquivalentTo &apos;erythroid progenitor cell&apos; and (&apos;has plasma membrane part&apos; some &apos;transferrin receptor protein 1&apos;) and (&apos;capable of&apos; some &apos;erythrocyte differentiation&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;)</deletedAxiom>
<deletedAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</deletedAxiom>
<newAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;</newAxiom>
<newAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;</newAxiom>
<newAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;</newAxiom>
<newAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</newAxiom>
<newAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;</newAxiom>
<newAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</newAxiom>
<newAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;</newAxiom>
<newAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;</newAxiom>
<newAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;</newAxiom>
<newAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;</newAxiom>
<newAxiom>&apos;erythroid progenitor cell, mammalian&apos; EquivalentTo &apos;erythroid progenitor cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;) and (&apos;has plasma membrane part&apos; some &apos;transferrin receptor protein 1&apos;) and (&apos;capable of&apos; some &apos;erythrocyte differentiation&apos;)</newAxiom>
<newAxiom>&apos;erythroid progenitor cell, mammalian&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0001060</classIRI>
<classLabel>hematopoietic oligopotent progenitor cell, lineage-negative</classLabel>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; EquivalentTo &apos;hematopoietic oligopotent progenitor cell&apos; and (&apos;bearer of&apos; some &apos;oligopotent&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;)</deletedAxiom>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;</deletedAxiom>
<newAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;</newAxiom>
<newAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;</newAxiom>
<newAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;</newAxiom>
<newAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;</newAxiom>
<newAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</newAxiom>
<newAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;</newAxiom>
<newAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</newAxiom>
<newAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;</newAxiom>
<newAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 76 (mouse)&apos;</newAxiom>
<newAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; EquivalentTo &apos;hematopoietic oligopotent progenitor cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 76 (mouse)&apos;) and (&apos;bearer of&apos; some &apos;oligopotent&apos;)</newAxiom>
<newAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;</newAxiom>
<newAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;</newAxiom>
<newAxiom>&apos;hematopoietic oligopotent progenitor cell, lineage-negative&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000410</classIRI>
<classLabel>myocyte of atrioventricular node</classLabel>
<newAxiom>&apos;myocyte of atrioventricular node&apos; SubClassOf &apos;transversely striated visceral muscle cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000409</classIRI>
<classLabel>myocyte of sinoatrial node</classLabel>
<newAxiom>&apos;myocyte of sinoatrial node&apos; SubClassOf &apos;transversely striated visceral muscle cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009100</classIRI>
<classLabel>glycoprotein metabolic process</classLabel>
<deletedAxiom>&apos;glycoprotein metabolic process&apos; SubClassOf &apos;cellular macromolecule metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009101</classIRI>
<classLabel>glycoprotein biosynthetic process</classLabel>
<deletedAxiom>&apos;glycoprotein biosynthetic process&apos; SubClassOf &apos;cellular macromolecule biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;glycoprotein biosynthetic process&apos; SubClassOf &apos;macromolecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000222</classIRI>
<classLabel>stomach neuroendocrine cell</classLabel>
<deletedAxiom>&apos;stomach neuroendocrine cell&apos; SubClassOf &apos;epithelial cell of stomach&apos;</deletedAxiom>
<newAxiom>&apos;stomach neuroendocrine cell&apos; SubClassOf &apos;enteroendocrine cell&apos;</newAxiom>
<newAxiom>&apos;stomach neuroendocrine cell&apos; SubClassOf &apos;glandular cell of stomach&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006909</classIRI>
<classLabel>phagocytosis</classLabel>
<deletedAxiom>&apos;phagocytosis&apos; SubClassOf &apos;vesicle-mediated transport&apos;</deletedAxiom>
<newAxiom>&apos;phagocytosis&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0006897</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901338</classIRI>
<classLabel>catecholamine binding</classLabel>
<deletedAxiom>&apos;catecholamine binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;catecholamine&apos;)</deletedAxiom>
<deletedAxiom>&apos;catecholamine binding&apos; SubClassOf &apos;organic cyclic compound binding&apos;</deletedAxiom>
<deletedAxiom>&apos;catecholamine binding&apos; SubClassOf &apos;has input&apos; some &apos;catecholamine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002454</classIRI>
<classLabel>Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell</classLabel>
<deletedAxiom>&apos;Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</deletedAxiom>
<deletedAxiom>&apos;Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell&apos; EquivalentTo &apos;CD11b-positive dendritic cell&apos; and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;)</deletedAxiom>
<deletedAxiom>&apos;Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;</deletedAxiom>
<newAxiom>&apos;Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;</newAxiom>
<newAxiom>&apos;Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</newAxiom>
<newAxiom>&apos;Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell&apos; EquivalentTo &apos;CD11b-positive dendritic cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000272</classIRI>
<classLabel>lung secretory cell</classLabel>
<newAxiom>&apos;lung secretory cell&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000271</classIRI>
<classLabel>lung ciliated cell</classLabel>
<newAxiom>&apos;lung ciliated cell&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005539</classIRI>
<classLabel>glycosaminoglycan binding</classLabel>
<deletedAxiom>&apos;glycosaminoglycan binding&apos; SubClassOf &apos;carbohydrate derivative binding&apos;</deletedAxiom>
<deletedAxiom>&apos;glycosaminoglycan binding&apos; SubClassOf &apos;has input&apos; some &apos;glycosaminoglycan&apos;</deletedAxiom>
<deletedAxiom>&apos;glycosaminoglycan binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;glycosaminoglycan&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005540</classIRI>
<classLabel>hyaluronic acid binding</classLabel>
<deletedAxiom>&apos;hyaluronic acid binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;hyaluronic acid&apos;)</deletedAxiom>
<deletedAxiom>&apos;hyaluronic acid binding&apos; SubClassOf &apos;glycosaminoglycan binding&apos;</deletedAxiom>
<deletedAxiom>&apos;hyaluronic acid binding&apos; SubClassOf &apos;has input&apos; some &apos;hyaluronic acid&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006879</classIRI>
<classLabel>intracellular iron ion homeostasis</classLabel>
<deletedAxiom>&apos;intracellular iron ion homeostasis&apos; SubClassOf &apos;iron ion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;intracellular iron ion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;iron cation&apos;</newAxiom>
<newAxiom>&apos;intracellular iron ion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002485</classIRI>
<classLabel>retinal melanocyte</classLabel>
<newAxiom>&apos;retinal melanocyte&apos; SubClassOf &apos;retinal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097690</classIRI>
<classLabel>iron ion transmembrane transporter inhibitor activity</classLabel>
<deletedAxiom>&apos;iron ion transmembrane transporter inhibitor activity&apos; SubClassOf &apos;directly negatively regulates&apos; some &apos;iron ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;iron ion transmembrane transporter inhibitor activity&apos; SubClassOf &apos;molecular function inhibitor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;iron ion transmembrane transporter inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;directly negatively regulates&apos; some &apos;iron ion transmembrane transporter activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002494</classIRI>
<classLabel>cardiocyte</classLabel>
<deletedAxiom>&apos;cardiocyte&apos; SubClassOf &apos;animal cell&apos;</deletedAxiom>
<deletedAxiom>&apos;cardiocyte&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042562</classIRI>
<classLabel>hormone binding</classLabel>
<deletedAxiom>&apos;hormone binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000785</classIRI>
<classLabel>chromatin</classLabel>
<deletedAxiom>&apos;chromatin&apos; SubClassOf &apos;cellular anatomical entity&apos;</deletedAxiom>
<newAxiom>&apos;chromatin&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0032993</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000763</classIRI>
<classLabel>myeloid cell</classLabel>
<deletedAxiom>&apos;myeloid cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000765</classIRI>
<classLabel>erythroblast</classLabel>
<deletedAxiom>&apos;erythroblast&apos; EquivalentTo &apos;erythroid lineage cell&apos; and (&apos;has_part&apos; some &apos;nucleus&apos;) and (&apos;capable of&apos; some &apos;erythrocyte differentiation&apos;) and (&apos;lacks_part&apos; some &apos;nucleolus&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;)</deletedAxiom>
<deletedAxiom>&apos;erythroblast&apos; SubClassOf &apos;lacks_part&apos; some &apos;nucleolus&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;</deletedAxiom>
<deletedAxiom>&apos;erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</deletedAxiom>
<newAxiom>&apos;erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;</newAxiom>
<newAxiom>&apos;erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;</newAxiom>
<newAxiom>&apos;erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;</newAxiom>
<newAxiom>&apos;erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;</newAxiom>
<newAxiom>&apos;erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;</newAxiom>
<newAxiom>&apos;erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</newAxiom>
<newAxiom>&apos;erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030045 some &apos;nucleolus&apos;</newAxiom>
<newAxiom>&apos;erythroblast&apos; EquivalentTo &apos;erythroid lineage cell&apos; and (&apos;has_part&apos; some &apos;nucleus&apos;) and (http://purl.obolibrary.org/obo/CL_4030045 some &apos;nucleolus&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;) and (&apos;capable of&apos; some &apos;erythrocyte differentiation&apos;)</newAxiom>
<newAxiom>&apos;erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</newAxiom>
<newAxiom>&apos;erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;</newAxiom>
<newAxiom>&apos;erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;</newAxiom>
<newAxiom>&apos;erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;</newAxiom>
<newAxiom>&apos;erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000782</classIRI>
<classLabel>myeloid dendritic cell</classLabel>
<deletedAxiom>&apos;myeloid dendritic cell&apos; EquivalentTo &apos;conventional dendritic cell&apos; and (&apos;develops from&apos; some &apos;myeloid cell&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-3 receptor class 2 alpha chain&apos;)</deletedAxiom>
<deletedAxiom>&apos;myeloid dendritic cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-3 receptor class 2 alpha chain&apos;</deletedAxiom>
<newAxiom>&apos;myeloid dendritic cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-3 receptor class 2 alpha chain&apos;</newAxiom>
<newAxiom>&apos;myeloid dendritic cell&apos; EquivalentTo &apos;conventional dendritic cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-3 receptor class 2 alpha chain&apos;) and (&apos;develops from&apos; some &apos;myeloid cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061629</classIRI>
<classLabel>RNA polymerase II-specific DNA-binding transcription factor binding</classLabel>
<deletedAxiom>&apos;RNA polymerase II-specific DNA-binding transcription factor binding&apos; SubClassOf &apos;DNA-binding transcription factor binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900120</classIRI>
<classLabel>regulation of receptor binding</classLabel>
<deletedAxiom>&apos;regulation of receptor binding&apos; SubClassOf &apos;regulates&apos; some &apos;signaling receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of receptor binding&apos; SubClassOf &apos;regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of receptor binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;signaling receptor binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900121</classIRI>
<classLabel>negative regulation of receptor binding</classLabel>
<deletedAxiom>&apos;negative regulation of receptor binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;signaling receptor binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of receptor binding&apos; SubClassOf &apos;negative regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of receptor binding&apos; SubClassOf &apos;regulation of receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of receptor binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;signaling receptor binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900122</classIRI>
<classLabel>positive regulation of receptor binding</classLabel>
<deletedAxiom>&apos;positive regulation of receptor binding&apos; SubClassOf &apos;positive regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of receptor binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;signaling receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of receptor binding&apos; SubClassOf &apos;regulation of receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of receptor binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;signaling receptor binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005506</classIRI>
<classLabel>iron ion binding</classLabel>
<deletedAxiom>&apos;iron ion binding&apos; SubClassOf &apos;transition metal ion binding&apos;</deletedAxiom>
<deletedAxiom>&apos;iron ion binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;iron cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;iron ion binding&apos; SubClassOf &apos;has input&apos; some &apos;iron cation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900130</classIRI>
<classLabel>regulation of lipid binding</classLabel>
<deletedAxiom>&apos;regulation of lipid binding&apos; SubClassOf &apos;regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of lipid binding&apos; SubClassOf &apos;regulates&apos; some &apos;lipid binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of lipid binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;lipid binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900131</classIRI>
<classLabel>negative regulation of lipid binding</classLabel>
<deletedAxiom>&apos;negative regulation of lipid binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;lipid binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of lipid binding&apos; SubClassOf &apos;negative regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of lipid binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;lipid binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of lipid binding&apos; SubClassOf &apos;regulation of lipid binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900132</classIRI>
<classLabel>positive regulation of lipid binding</classLabel>
<deletedAxiom>&apos;positive regulation of lipid binding&apos; SubClassOf &apos;positive regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of lipid binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;lipid binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of lipid binding&apos; SubClassOf &apos;regulation of lipid binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of lipid binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;lipid binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005515</classIRI>
<classLabel>protein binding</classLabel>
<deletedAxiom>&apos;protein binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;protein&apos;)</deletedAxiom>
<deletedAxiom>&apos;protein binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;protein binding&apos; SubClassOf &apos;has input&apos; some &apos;protein&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005518</classIRI>
<classLabel>collagen binding</classLabel>
<deletedAxiom>&apos;collagen binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;collagen trimer&apos;)</deletedAxiom>
<deletedAxiom>&apos;collagen binding&apos; SubClassOf &apos;has input&apos; some &apos;collagen trimer&apos;</deletedAxiom>
<deletedAxiom>&apos;collagen binding&apos; SubClassOf &apos;protein-containing complex binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005536</classIRI>
<classLabel>glucose binding</classLabel>
<deletedAxiom>&apos;glucose binding&apos; SubClassOf &apos;monosaccharide binding&apos;</deletedAxiom>
<deletedAxiom>&apos;glucose binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;glucose&apos;)</deletedAxiom>
<deletedAxiom>&apos;glucose binding&apos; SubClassOf &apos;has input&apos; some &apos;glucose&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901363</classIRI>
<classLabel>heterocyclic compound binding</classLabel>
<deletedAxiom>&apos;heterocyclic compound binding&apos; SubClassOf &apos;has input&apos; some &apos;heterocyclic compound&apos;</deletedAxiom>
<deletedAxiom>&apos;heterocyclic compound binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;heterocyclic compound&apos;)</deletedAxiom>
<deletedAxiom>&apos;heterocyclic compound binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005488</classIRI>
<classLabel>binding</classLabel>
<deletedAxiom>&apos;binding&apos; SubClassOf &apos;molecular_function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005496</classIRI>
<classLabel>steroid binding</classLabel>
<deletedAxiom>&apos;steroid binding&apos; SubClassOf &apos;organic cyclic compound binding&apos;</deletedAxiom>
<deletedAxiom>&apos;steroid binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;steroid&apos;)</deletedAxiom>
<deletedAxiom>&apos;steroid binding&apos; SubClassOf &apos;lipid binding&apos;</deletedAxiom>
<deletedAxiom>&apos;steroid binding&apos; SubClassOf &apos;has input&apos; some &apos;steroid&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000837</classIRI>
<classLabel>hematopoietic multipotent progenitor cell</classLabel>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;hematopoietic multipotent progenitor cell&apos; EquivalentTo &apos;hematopoietic cell&apos; and (&apos;bearer of&apos; some &apos;multipotent&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;)</deletedAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; EquivalentTo &apos;hematopoietic cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 76 (mouse)&apos;) and (&apos;bearer of&apos; some &apos;multipotent&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;)</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf &apos;protein-containing material entity&apos;</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 76 (mouse)&apos;</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</newAxiom>
<newAxiom>&apos;hematopoietic multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000836</classIRI>
<classLabel>promyelocyte</classLabel>
<deletedAxiom>&apos;promyelocyte&apos; EquivalentTo &apos;myeloid lineage restricted progenitor cell&apos; and (&apos;has_part&apos; some &apos;basophilic cytoplasm&apos;) and (&apos;has_part&apos; some &apos;increased nucleus size&apos;) and (&apos;has_part&apos; some &apos;nucleolus&apos;) and (&apos;has_part&apos; some &apos;azurophil granule&apos;) and (&apos;has plasma membrane part&apos; some &apos;alpha-(1,3)-fucosyltransferase 4&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD33 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;low affinity immunoglobulin gamma Fc region receptor III&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;signal transducer CD24&apos;)</deletedAxiom>
<deletedAxiom>&apos;promyelocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;low affinity immunoglobulin gamma Fc region receptor III&apos;</deletedAxiom>
<deletedAxiom>&apos;promyelocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;</deletedAxiom>
<deletedAxiom>&apos;promyelocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;signal transducer CD24&apos;</deletedAxiom>
<newAxiom>&apos;promyelocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;</newAxiom>
<newAxiom>&apos;promyelocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;low affinity immunoglobulin gamma Fc region receptor III&apos;</newAxiom>
<newAxiom>&apos;promyelocyte&apos; EquivalentTo &apos;myeloid lineage restricted progenitor cell&apos; and (&apos;has_part&apos; some &apos;basophilic cytoplasm&apos;) and (&apos;has_part&apos; some &apos;increased nucleus size&apos;) and (&apos;has_part&apos; some &apos;nucleolus&apos;) and (&apos;has_part&apos; some &apos;azurophil granule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;low affinity immunoglobulin gamma Fc region receptor III&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;signal transducer CD24&apos;) and (&apos;has plasma membrane part&apos; some &apos;alpha-(1,3)-fucosyltransferase 4&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD33 molecule&apos;)</newAxiom>
<newAxiom>&apos;promyelocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;signal transducer CD24&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000835</classIRI>
<classLabel>myeloblast</classLabel>
<deletedAxiom>&apos;myeloblast&apos; EquivalentTo &apos;granulocytopoietic cell&apos; and (&apos;has_part&apos; some &apos;basophilic cytoplasm&apos;) and (&apos;has_part&apos; some &apos;increased nucleus size&apos;) and (&apos;has_part&apos; some &apos;euchromatin&apos;) and (&apos;lacks_part&apos; some &apos;azurophil granule&apos;)</deletedAxiom>
<deletedAxiom>&apos;myeloblast&apos; SubClassOf &apos;lacks_part&apos; some &apos;azurophil granule&apos;</deletedAxiom>
<newAxiom>&apos;myeloblast&apos; SubClassOf &apos;protein-containing material entity&apos;</newAxiom>
<newAxiom>&apos;myeloblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030045 some &apos;azurophil granule&apos;</newAxiom>
<newAxiom>&apos;myeloblast&apos; EquivalentTo &apos;granulocytopoietic cell&apos; and (&apos;has_part&apos; some &apos;basophilic cytoplasm&apos;) and (&apos;has_part&apos; some &apos;increased nucleus size&apos;) and (&apos;has_part&apos; some &apos;euchromatin&apos;) and (http://purl.obolibrary.org/obo/CL_4030045 some &apos;azurophil granule&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000488</classIRI>
<classLabel>cholangiocyte</classLabel>
<deletedAxiom>&apos;cholangiocyte&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050839</classIRI>
<classLabel>cell adhesion molecule binding</classLabel>
<deletedAxiom>&apos;cell adhesion molecule binding&apos; SubClassOf &apos;protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050840</classIRI>
<classLabel>extracellular matrix binding</classLabel>
<deletedAxiom>&apos;extracellular matrix binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;extracellular matrix binding&apos; SubClassOf &apos;has input&apos; some &apos;extracellular matrix&apos;</deletedAxiom>
<deletedAxiom>&apos;extracellular matrix binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;extracellular matrix&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004111</classIRI>
<classLabel>anatomical conduit</classLabel>
<deletedAxiom>&apos;anatomical conduit&apos; EquivalentTo &apos;multicellular anatomical structure&apos; and (&apos;has_part&apos; some &apos;anatomical conduit space&apos;) and (&apos;conduit for&apos; some &apos;anatomical structure&apos;)</deletedAxiom>
<deletedAxiom>&apos;anatomical conduit&apos; SubClassOf &apos;conduit for&apos; some &apos;anatomical structure&apos;</deletedAxiom>
<newAxiom>&apos;anatomical conduit&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002570 some &apos;anatomical structure&apos;</newAxiom>
<newAxiom>&apos;anatomical conduit&apos; EquivalentTo &apos;multicellular anatomical structure&apos; and (&apos;has_part&apos; some &apos;anatomical conduit space&apos;) and (http://purl.obolibrary.org/obo/RO_0002570 some &apos;anatomical structure&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005456</classIRI>
<classLabel>jugular foramen</classLabel>
<deletedAxiom>&apos;jugular foramen&apos; SubClassOf &apos;conduit for&apos; some &apos;vagus nerve&apos;</deletedAxiom>
<deletedAxiom>&apos;jugular foramen&apos; SubClassOf &apos;conduit for&apos; some &apos;accessory XI nerve&apos;</deletedAxiom>
<deletedAxiom>&apos;jugular foramen&apos; EquivalentTo &apos;foramen of skull&apos; and (&apos;part of&apos; some &apos;temporal bone&apos;) and (&apos;conduit for&apos; some &apos;internal jugular vein&apos;)</deletedAxiom>
<deletedAxiom>&apos;jugular foramen&apos; SubClassOf &apos;conduit for&apos; some &apos;internal jugular vein&apos;</deletedAxiom>
<newAxiom>&apos;jugular foramen&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002570 some &apos;accessory XI nerve&apos;</newAxiom>
<newAxiom>&apos;jugular foramen&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002570 some &apos;vagus nerve&apos;</newAxiom>
<newAxiom>&apos;jugular foramen&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002570 some &apos;internal jugular vein&apos;</newAxiom>
<newAxiom>&apos;jugular foramen&apos; EquivalentTo &apos;foramen of skull&apos; and (&apos;part of&apos; some &apos;temporal bone&apos;) and (http://purl.obolibrary.org/obo/RO_0002570 some &apos;internal jugular vein&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061535</classIRI>
<classLabel>glutamate secretion, neurotransmission</classLabel>
<newAxiom>&apos;glutamate secretion, neurotransmission&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0051938</newAxiom>
<newAxiom>&apos;glutamate secretion, neurotransmission&apos; EquivalentTo &apos;neurotransmitter secretion&apos; and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29985)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098772</classIRI>
<classLabel>molecular function regulator activity</classLabel>
<deletedAxiom>&apos;molecular function regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly regulates&apos; some &apos;molecular_function&apos;)</deletedAxiom>
<deletedAxiom>&apos;molecular function regulator activity&apos; SubClassOf &apos;has_part&apos; some &apos;protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;molecular function regulator activity&apos; SubClassOf &apos;directly regulates&apos; some &apos;molecular_function&apos;</deletedAxiom>
<deletedAxiom>&apos;molecular function regulator activity&apos; SubClassOf &apos;molecular_function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000112</classIRI>
<classLabel>regulation of cellular macromolecule biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of cellular macromolecule biosynthetic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;cellular macromolecule biosynthetic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular macromolecule biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular macromolecule biosynthetic process&apos; SubClassOf &apos;regulation of macromolecule biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular macromolecule biosynthetic process&apos; SubClassOf &apos;regulates&apos; some &apos;cellular macromolecule biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000113</classIRI>
<classLabel>negative regulation of cellular macromolecule biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of cellular macromolecule biosynthetic process&apos; SubClassOf &apos;negative regulation of macromolecule biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular macromolecule biosynthetic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;cellular macromolecule biosynthetic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular macromolecule biosynthetic process&apos; SubClassOf &apos;negatively regulates&apos; some &apos;cellular macromolecule biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular macromolecule biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular macromolecule biosynthetic process&apos; SubClassOf &apos;regulation of cellular macromolecule biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042301</classIRI>
<classLabel>phosphate ion binding</classLabel>
<deletedAxiom>&apos;phosphate ion binding&apos; SubClassOf &apos;anion binding&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphate ion binding&apos; SubClassOf &apos;has input&apos; some &apos;phosphate ion&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphate ion binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;phosphate ion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042277</classIRI>
<classLabel>peptide binding</classLabel>
<deletedAxiom>&apos;peptide binding&apos; SubClassOf &apos;amide binding&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide binding&apos; SubClassOf &apos;has input&apos; some &apos;peptide&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;peptide&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000988</classIRI>
<classLabel>hematopoietic cell</classLabel>
<deletedAxiom>&apos;hematopoietic cell&apos; SubClassOf &apos;animal cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0008007</classIRI>
<classLabel>visceral muscle cell</classLabel>
<newAxiom>&apos;visceral muscle cell&apos; SubClassOf &apos;part of&apos; some http://purl.obolibrary.org/obo/UBERON_8600004</newAxiom>
<newAxiom>&apos;visceral muscle cell&apos; EquivalentTo &apos;muscle cell&apos; and (&apos;part of&apos; some http://purl.obolibrary.org/obo/UBERON_8600004)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0008024</classIRI>
<classLabel>pancreatic endocrine cell</classLabel>
<deletedAxiom>&apos;pancreatic endocrine cell&apos; SubClassOf &apos;endocrine cell&apos;</deletedAxiom>
<deletedAxiom>&apos;pancreatic endocrine cell&apos; SubClassOf &apos;part of&apos; some &apos;pancreas&apos;</deletedAxiom>
<newAxiom>&apos;pancreatic endocrine cell&apos; SubClassOf &apos;enteroendocrine cell&apos;</newAxiom>
<newAxiom>&apos;pancreatic endocrine cell&apos; SubClassOf &apos;epithelial cell of pancreas&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006668</classIRI>
<classLabel>carotid canal</classLabel>
<deletedAxiom>&apos;carotid canal&apos; SubClassOf &apos;conduit for&apos; some &apos;internal carotid artery&apos;</deletedAxiom>
<deletedAxiom>&apos;carotid canal&apos; EquivalentTo &apos;foramen of skull&apos; and (&apos;conduit for&apos; some &apos;internal carotid artery&apos;)</deletedAxiom>
<newAxiom>&apos;carotid canal&apos; EquivalentTo &apos;foramen of skull&apos; and (http://purl.obolibrary.org/obo/RO_0002570 some &apos;internal carotid artery&apos;)</newAxiom>
<newAxiom>&apos;carotid canal&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002570 some &apos;internal carotid artery&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050764</classIRI>
<classLabel>regulation of phagocytosis</classLabel>
<deletedAxiom>&apos;regulation of phagocytosis&apos; SubClassOf &apos;regulation of vesicle-mediated transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of phagocytosis&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0030100</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050765</classIRI>
<classLabel>negative regulation of phagocytosis</classLabel>
<deletedAxiom>&apos;negative regulation of phagocytosis&apos; SubClassOf &apos;negative regulation of transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of phagocytosis&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0045806</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050766</classIRI>
<classLabel>positive regulation of phagocytosis</classLabel>
<deletedAxiom>&apos;positive regulation of phagocytosis&apos; SubClassOf &apos;positive regulation of transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of phagocytosis&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0045807</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901681</classIRI>
<classLabel>sulfur compound binding</classLabel>
<deletedAxiom>&apos;sulfur compound binding&apos; SubClassOf &apos;has input&apos; some &apos;sulfur molecular entity&apos;</deletedAxiom>
<deletedAxiom>&apos;sulfur compound binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;sulfur compound binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;sulfur molecular entity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019825</classIRI>
<classLabel>oxygen binding</classLabel>
<deletedAxiom>&apos;oxygen binding&apos; SubClassOf &apos;small molecule binding&apos;</deletedAxiom>
<deletedAxiom>&apos;oxygen binding&apos; SubClassOf &apos;has input&apos; some &apos;dioxygen&apos;</deletedAxiom>
<deletedAxiom>&apos;oxygen binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;dioxygen&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006516</classIRI>
<classLabel>glycoprotein catabolic process</classLabel>
<deletedAxiom>&apos;glycoprotein catabolic process&apos; SubClassOf &apos;cellular macromolecule catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098657</classIRI>
<classLabel>import into cell</classLabel>
<deletedAxiom>&apos;import into cell&apos; SubClassOf &apos;has target end location&apos; some &apos;intracellular anatomical structure&apos;</deletedAxiom>
<deletedAxiom>&apos;import into cell&apos; EquivalentTo &apos;transport&apos; and (&apos;has target start location&apos; some &apos;extracellular region&apos;) and (&apos;has target end location&apos; some &apos;intracellular anatomical structure&apos;) and (&apos;has primary input&apos; some &apos;chemical entity&apos;)</deletedAxiom>
<newAxiom>&apos;import into cell&apos; EquivalentTo &apos;transport&apos; and (&apos;has target start location&apos; some &apos;extracellular region&apos;) and (&apos;has target end location&apos; some &apos;cytoplasm&apos;) and (&apos;has primary input&apos; some &apos;chemical entity&apos;)</newAxiom>
<newAxiom>&apos;import into cell&apos; SubClassOf &apos;has target end location&apos; some &apos;cytoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044815</classIRI>
<classLabel>DNA packaging complex</classLabel>
<deletedAxiom>&apos;DNA packaging complex&apos; SubClassOf &apos;capable of part of&apos; some &apos;chromosome organization&apos;</deletedAxiom>
<deletedAxiom>&apos;DNA packaging complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<deletedAxiom>&apos;DNA packaging complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of part of&apos; some &apos;chromosome organization&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_4030034</classIRI>
<classLabel>respiratory ciliated cell</classLabel>
<deletedAxiom>&apos;respiratory ciliated cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006682</classIRI>
<classLabel>hypoglossal canal</classLabel>
<deletedAxiom>&apos;hypoglossal canal&apos; SubClassOf &apos;conduit for&apos; some &apos;hypoglossal nerve&apos;</deletedAxiom>
<deletedAxiom>&apos;hypoglossal canal&apos; EquivalentTo &apos;anatomical conduit&apos; and (&apos;conduit for&apos; some &apos;hypoglossal nerve&apos;)</deletedAxiom>
<newAxiom>&apos;hypoglossal canal&apos; EquivalentTo &apos;anatomical conduit&apos; and (http://purl.obolibrary.org/obo/RO_0002570 some &apos;hypoglossal nerve&apos;)</newAxiom>
<newAxiom>&apos;hypoglossal canal&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002570 some &apos;hypoglossal nerve&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150005</classIRI>
<classLabel>enzyme activator complex</classLabel>
<deletedAxiom>&apos;enzyme activator complex&apos; SubClassOf &apos;capable of&apos; some &apos;enzyme activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;enzyme activator complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;enzyme activator activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;enzyme activator complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098631</classIRI>
<classLabel>cell adhesion mediator activity</classLabel>
<deletedAxiom>&apos;cell adhesion mediator activity&apos; SubClassOf &apos;cell adhesion molecule binding&apos;</deletedAxiom>
<deletedAxiom>&apos;cell adhesion mediator activity&apos; SubClassOf &apos;part of&apos; some &apos;cell adhesion&apos;</deletedAxiom>
<deletedAxiom>&apos;cell adhesion mediator activity&apos; EquivalentTo &apos;binding&apos; and (&apos;part of&apos; some &apos;cell adhesion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098632</classIRI>
<classLabel>cell-cell adhesion mediator activity</classLabel>
<deletedAxiom>&apos;cell-cell adhesion mediator activity&apos; SubClassOf &apos;part of&apos; some &apos;cell-cell adhesion&apos;</deletedAxiom>
<deletedAxiom>&apos;cell-cell adhesion mediator activity&apos; EquivalentTo &apos;protein binding&apos; and (&apos;part of&apos; some &apos;cell-cell adhesion&apos;)</deletedAxiom>
<deletedAxiom>&apos;cell-cell adhesion mediator activity&apos; SubClassOf &apos;cell adhesion mediator activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098633</classIRI>
<classLabel>collagen fibril binding</classLabel>
<deletedAxiom>&apos;collagen fibril binding&apos; SubClassOf &apos;protein-containing complex binding&apos;</deletedAxiom>
<deletedAxiom>&apos;collagen fibril binding&apos; SubClassOf &apos;has input&apos; some &apos;banded collagen fibril&apos;</deletedAxiom>
<deletedAxiom>&apos;collagen fibril binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;banded collagen fibril&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140677</classIRI>
<classLabel>molecular function activator activity</classLabel>
<deletedAxiom>&apos;molecular function activator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;directly positively regulates&apos; some &apos;molecular_function&apos;)</deletedAxiom>
<deletedAxiom>&apos;molecular function activator activity&apos; SubClassOf &apos;molecular function regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;molecular function activator activity&apos; SubClassOf &apos;directly positively regulates&apos; some &apos;molecular_function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140678</classIRI>
<classLabel>molecular function inhibitor activity</classLabel>
<deletedAxiom>&apos;molecular function inhibitor activity&apos; SubClassOf &apos;directly negatively regulates&apos; some &apos;molecular_function&apos;</deletedAxiom>
<deletedAxiom>&apos;molecular function inhibitor activity&apos; SubClassOf &apos;molecular function regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;molecular function inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;directly negatively regulates&apos; some &apos;molecular_function&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098641</classIRI>
<classLabel>cadherin binding involved in cell-cell adhesion</classLabel>
<deletedAxiom>&apos;cadherin binding involved in cell-cell adhesion&apos; SubClassOf &apos;cell-cell adhesion mediator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;cadherin binding involved in cell-cell adhesion&apos; EquivalentTo &apos;cadherin binding&apos; and (&apos;part of&apos; some &apos;cell-cell adhesion&apos;)</deletedAxiom>
<deletedAxiom>&apos;cadherin binding involved in cell-cell adhesion&apos; SubClassOf &apos;cadherin binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030234</classIRI>
<classLabel>enzyme regulator activity</classLabel>
<deletedAxiom>&apos;enzyme regulator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;regulates&apos; some &apos;catalytic activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;enzyme regulator activity&apos; SubClassOf &apos;regulates&apos; some &apos;catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;enzyme regulator activity&apos; SubClassOf &apos;molecular function regulator activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044877</classIRI>
<classLabel>protein-containing complex binding</classLabel>
<deletedAxiom>&apos;protein-containing complex binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;protein-containing complex&apos;)</deletedAxiom>
<deletedAxiom>&apos;protein-containing complex binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;protein-containing complex binding&apos; SubClassOf &apos;has input&apos; some &apos;protein-containing complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097367</classIRI>
<classLabel>carbohydrate derivative binding</classLabel>
<deletedAxiom>&apos;carbohydrate derivative binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;carbohydrate derivative&apos;)</deletedAxiom>
<deletedAxiom>&apos;carbohydrate derivative binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;carbohydrate derivative binding&apos; SubClassOf &apos;has input&apos; some &apos;carbohydrate derivative&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030246</classIRI>
<classLabel>carbohydrate binding</classLabel>
<deletedAxiom>&apos;carbohydrate binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;carbohydrate&apos;)</deletedAxiom>
<deletedAxiom>&apos;carbohydrate binding&apos; SubClassOf &apos;has input&apos; some &apos;carbohydrate&apos;</deletedAxiom>
<deletedAxiom>&apos;carbohydrate binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030247</classIRI>
<classLabel>polysaccharide binding</classLabel>
<deletedAxiom>&apos;polysaccharide binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;polysaccharide&apos;)</deletedAxiom>
<deletedAxiom>&apos;polysaccharide binding&apos; SubClassOf &apos;has input&apos; some &apos;polysaccharide&apos;</deletedAxiom>
<deletedAxiom>&apos;polysaccharide binding&apos; SubClassOf &apos;carbohydrate binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043559</classIRI>
<classLabel>insulin binding</classLabel>
<deletedAxiom>&apos;insulin binding&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Fungi&apos;)</deletedAxiom>
<deletedAxiom>&apos;insulin binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;insulin gene translation product&apos;)</deletedAxiom>
<deletedAxiom>&apos;insulin binding&apos; SubClassOf &apos;peptide hormone binding&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin binding&apos; SubClassOf &apos;protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin binding&apos; SubClassOf &apos;has input&apos; some &apos;insulin gene translation product&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin binding&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Fungi&apos;))</deletedAxiom>
<deletedAxiom>&apos;insulin binding&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042166</classIRI>
<classLabel>acetylcholine binding</classLabel>
<deletedAxiom>&apos;acetylcholine binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;acetylcholine&apos;)</deletedAxiom>
<deletedAxiom>&apos;acetylcholine binding&apos; SubClassOf &apos;cation binding&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine binding&apos; SubClassOf &apos;neurotransmitter binding&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine binding&apos; SubClassOf &apos;has input&apos; some &apos;acetylcholine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042165</classIRI>
<classLabel>neurotransmitter binding</classLabel>
<deletedAxiom>&apos;neurotransmitter binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_4023079</classIRI>
<classLabel>midbrain-derived inhibitory neuron</classLabel>
<newAxiom>&apos;midbrain-derived inhibitory neuron&apos; SubClassOf &apos;ectoderm-derived structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_4023072</classIRI>
<classLabel>brain vascular cell</classLabel>
<deletedAxiom>&apos;brain vascular cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0023023</classIRI>
<classLabel>MHC protein complex binding</classLabel>
<deletedAxiom>&apos;MHC protein complex binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;MHC protein complex&apos;)</deletedAxiom>
<deletedAxiom>&apos;MHC protein complex binding&apos; SubClassOf &apos;protein-containing complex binding&apos;</deletedAxiom>
<deletedAxiom>&apos;MHC protein complex binding&apos; SubClassOf &apos;has input&apos; some &apos;MHC protein complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0023026</classIRI>
<classLabel>MHC class II protein complex binding</classLabel>
<deletedAxiom>&apos;MHC class II protein complex binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;MHC class II protein complex&apos;)</deletedAxiom>
<deletedAxiom>&apos;MHC class II protein complex binding&apos; SubClassOf &apos;has input&apos; some &apos;MHC class II protein complex&apos;</deletedAxiom>
<deletedAxiom>&apos;MHC class II protein complex binding&apos; SubClassOf &apos;MHC protein complex binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005203</classIRI>
<classLabel>trachea gland</classLabel>
<deletedAxiom>&apos;trachea gland&apos; SubClassOf &apos;part of&apos; some &apos;submucosa of trachea&apos;</deletedAxiom>
<deletedAxiom>&apos;trachea gland&apos; EquivalentTo &apos;submucosal gland&apos; and (&apos;part of&apos; some &apos;submucosa of trachea&apos;) and (&apos;has_part&apos; some &apos;seromucus secreting cell&apos;)</deletedAxiom>
<newAxiom>&apos;trachea gland&apos; SubClassOf &apos;part of&apos; some &apos;trachea&apos;</newAxiom>
<newAxiom>&apos;trachea gland&apos; EquivalentTo &apos;submucosal gland&apos; and (&apos;part of&apos; some &apos;trachea&apos;) and (&apos;has_part&apos; some &apos;seromucus secreting cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0023052</classIRI>
<classLabel>signaling</classLabel>
<deletedAxiom>&apos;signaling&apos; SubClassOf &apos;biological_process&apos;</deletedAxiom>
<newAxiom>&apos;signaling&apos; SubClassOf &apos;regulation of biological process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002005</classIRI>
<classLabel>CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell</classLabel>
<deletedAxiom>&apos;CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-3 receptor class 2 alpha chain&apos;</deletedAxiom>
<deletedAxiom>&apos;CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell&apos; EquivalentTo &apos;megakaryocyte-erythroid progenitor cell&apos; and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;) and (&apos;has plasma membrane part&apos; some &apos;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-3 receptor class 2 alpha chain&apos;)</deletedAxiom>
<deletedAxiom>&apos;CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;</deletedAxiom>
<newAxiom>&apos;CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;</newAxiom>
<newAxiom>&apos;CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell&apos; EquivalentTo &apos;megakaryocyte-erythroid progenitor cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-3 receptor class 2 alpha chain&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;) and (&apos;has plasma membrane part&apos; some &apos;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1&apos;)</newAxiom>
<newAxiom>&apos;CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-3 receptor class 2 alpha chain&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002006</classIRI>
<classLabel>Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell</classLabel>
<deletedAxiom>&apos;Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;Thy-1 membrane glycoprotein&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;low affinity immunoglobulin gamma Fc region receptor II&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD34 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell&apos; EquivalentTo &apos;megakaryocyte-erythroid progenitor cell&apos; and (&apos;has plasma membrane part&apos; some &apos;mast/stem cell growth factor receptor&apos;) and (&apos;has low plasma membrane amount&apos; some &apos;Fc-gamma receptor III complex&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD34 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;low affinity immunoglobulin gamma Fc region receptor II&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;Thy-1 membrane glycoprotein&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;)</deletedAxiom>
<newAxiom>&apos;Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell&apos; EquivalentTo &apos;megakaryocyte-erythroid progenitor cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD34 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;low affinity immunoglobulin gamma Fc region receptor II&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;Thy-1 membrane glycoprotein&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6A-2/6E-1&apos;) and (&apos;has plasma membrane part&apos; some &apos;mast/stem cell growth factor receptor&apos;) and (&apos;has low plasma membrane amount&apos; some &apos;Fc-gamma receptor III complex&apos;)</newAxiom>
<newAxiom>&apos;Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6A-2/6E-1&apos;</newAxiom>
<newAxiom>&apos;Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;Thy-1 membrane glycoprotein&apos;</newAxiom>
<newAxiom>&apos;Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;</newAxiom>
<newAxiom>&apos;Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;low affinity immunoglobulin gamma Fc region receptor II&apos;</newAxiom>
<newAxiom>&apos;Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD34 molecule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002000</classIRI>
<classLabel>Kit-positive erythroid progenitor cell</classLabel>
<deletedAxiom>&apos;Kit-positive erythroid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;SLAM family member 1&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-positive erythroid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-positive erythroid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-positive erythroid progenitor cell&apos; EquivalentTo &apos;erythroid progenitor cell, mammalian&apos; and (&apos;has plasma membrane part&apos; some &apos;endoglin&apos;) and (&apos;has plasma membrane part&apos; some &apos;mast/stem cell growth factor receptor&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;Fc-gamma receptor III complex&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;SLAM family member 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-3 receptor class 2 alpha chain&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-IIb&apos;)</deletedAxiom>
<deletedAxiom>&apos;Kit-positive erythroid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-3 receptor class 2 alpha chain&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-positive erythroid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-IIb&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-positive erythroid progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;Fc-gamma receptor III complex&apos;</deletedAxiom>
<newAxiom>&apos;Kit-positive erythroid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6A-2/6E-1&apos;</newAxiom>
<newAxiom>&apos;Kit-positive erythroid progenitor cell&apos; EquivalentTo &apos;erythroid progenitor cell, mammalian&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;Fc-gamma receptor III complex&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;SLAM family member 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-3 receptor class 2 alpha chain&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6A-2/6E-1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-IIb&apos;) and (&apos;has plasma membrane part&apos; some &apos;endoglin&apos;) and (&apos;has plasma membrane part&apos; some &apos;mast/stem cell growth factor receptor&apos;)</newAxiom>
<newAxiom>&apos;Kit-positive erythroid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;Fc-gamma receptor III complex&apos;</newAxiom>
<newAxiom>&apos;Kit-positive erythroid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;</newAxiom>
<newAxiom>&apos;Kit-positive erythroid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-3 receptor class 2 alpha chain&apos;</newAxiom>
<newAxiom>&apos;Kit-positive erythroid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-IIb&apos;</newAxiom>
<newAxiom>&apos;Kit-positive erythroid progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;SLAM family member 1&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006401</classIRI>
<classLabel>RNA catabolic process</classLabel>
<deletedAxiom>&apos;RNA catabolic process&apos; SubClassOf &apos;cellular macromolecule catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;RNA catabolic process&apos; SubClassOf &apos;macromolecule catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002014</classIRI>
<classLabel>Kit-negative, Ly-76 high basophilic erythroblast</classLabel>
<deletedAxiom>&apos;Kit-negative, Ly-76 high basophilic erythroblast&apos; EquivalentTo &apos;basophilic erythroblast&apos; and (&apos;has high plasma membrane amount&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;mast/stem cell growth factor receptor&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;)</deletedAxiom>
<deletedAxiom>&apos;Kit-negative, Ly-76 high basophilic erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;mast/stem cell growth factor receptor&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-negative, Ly-76 high basophilic erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-negative, Ly-76 high basophilic erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;</deletedAxiom>
<newAxiom>&apos;Kit-negative, Ly-76 high basophilic erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;</newAxiom>
<newAxiom>&apos;Kit-negative, Ly-76 high basophilic erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6A-2/6E-1&apos;</newAxiom>
<newAxiom>&apos;Kit-negative, Ly-76 high basophilic erythroblast&apos; EquivalentTo &apos;basophilic erythroblast&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;mast/stem cell growth factor receptor&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6A-2/6E-1&apos;) and (&apos;has high plasma membrane amount&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;)</newAxiom>
<newAxiom>&apos;Kit-negative, Ly-76 high basophilic erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;mast/stem cell growth factor receptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002015</classIRI>
<classLabel>Kit-negative, Ly-76 high polychromatophilic erythroblast</classLabel>
<deletedAxiom>&apos;Kit-negative, Ly-76 high polychromatophilic erythroblast&apos; EquivalentTo &apos;polychromatophilic erythroblast&apos; and (&apos;has high plasma membrane amount&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;mast/stem cell growth factor receptor&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;)</deletedAxiom>
<deletedAxiom>&apos;Kit-negative, Ly-76 high polychromatophilic erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-negative, Ly-76 high polychromatophilic erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;mast/stem cell growth factor receptor&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-negative, Ly-76 high polychromatophilic erythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;</deletedAxiom>
<newAxiom>&apos;Kit-negative, Ly-76 high polychromatophilic erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;</newAxiom>
<newAxiom>&apos;Kit-negative, Ly-76 high polychromatophilic erythroblast&apos; EquivalentTo &apos;polychromatophilic erythroblast&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;mast/stem cell growth factor receptor&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6A-2/6E-1&apos;) and (&apos;has high plasma membrane amount&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;)</newAxiom>
<newAxiom>&apos;Kit-negative, Ly-76 high polychromatophilic erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;mast/stem cell growth factor receptor&apos;</newAxiom>
<newAxiom>&apos;Kit-negative, Ly-76 high polychromatophilic erythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6A-2/6E-1&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002017</classIRI>
<classLabel>Kit-negative, Ly-76 high orthochromatophilic erythroblasts</classLabel>
<deletedAxiom>&apos;Kit-negative, Ly-76 high orthochromatophilic erythroblasts&apos; EquivalentTo &apos;orthochromatic erythroblast&apos; and (&apos;has high plasma membrane amount&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;) and (&apos;has low plasma membrane amount&apos; some &apos;transferrin receptor protein 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;mast/stem cell growth factor receptor&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;)</deletedAxiom>
<deletedAxiom>&apos;Kit-negative, Ly-76 high orthochromatophilic erythroblasts&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;mast/stem cell growth factor receptor&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-negative, Ly-76 high orthochromatophilic erythroblasts&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-negative, Ly-76 high orthochromatophilic erythroblasts&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;</deletedAxiom>
<newAxiom>&apos;Kit-negative, Ly-76 high orthochromatophilic erythroblasts&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;mast/stem cell growth factor receptor&apos;</newAxiom>
<newAxiom>&apos;Kit-negative, Ly-76 high orthochromatophilic erythroblasts&apos; EquivalentTo &apos;orthochromatic erythroblast&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;mast/stem cell growth factor receptor&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6A-2/6E-1&apos;) and (&apos;has high plasma membrane amount&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;) and (&apos;has low plasma membrane amount&apos; some &apos;transferrin receptor protein 1&apos;)</newAxiom>
<newAxiom>&apos;Kit-negative, Ly-76 high orthochromatophilic erythroblasts&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6A-2/6E-1&apos;</newAxiom>
<newAxiom>&apos;Kit-negative, Ly-76 high orthochromatophilic erythroblasts&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002012</classIRI>
<classLabel>Kit-low proerythroblast</classLabel>
<deletedAxiom>&apos;Kit-low proerythroblast&apos; EquivalentTo &apos;proerythroblast&apos; and (&apos;has plasma membrane part&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;) and (&apos;has high plasma membrane amount&apos; some &apos;transferrin receptor protein 1&apos;) and (&apos;has low plasma membrane amount&apos; some &apos;mast/stem cell growth factor receptor&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;)</deletedAxiom>
<deletedAxiom>&apos;Kit-low proerythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;interleukin-7 receptor subunit alpha&apos;</deletedAxiom>
<deletedAxiom>&apos;Kit-low proerythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;</deletedAxiom>
<newAxiom>&apos;Kit-low proerythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6A-2/6E-1&apos;</newAxiom>
<newAxiom>&apos;Kit-low proerythroblast&apos; EquivalentTo &apos;proerythroblast&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6A-2/6E-1&apos;) and (&apos;has plasma membrane part&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;) and (&apos;has high plasma membrane amount&apos; some &apos;transferrin receptor protein 1&apos;) and (&apos;has low plasma membrane amount&apos; some &apos;mast/stem cell growth factor receptor&apos;)</newAxiom>
<newAxiom>&apos;Kit-low proerythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;interleukin-7 receptor subunit alpha&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006412</classIRI>
<classLabel>translation</classLabel>
<deletedAxiom>&apos;translation&apos; SubClassOf &apos;cellular macromolecule biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;translation&apos; SubClassOf &apos;macromolecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006414</classIRI>
<classLabel>translational elongation</classLabel>
<deletedAxiom>&apos;translational elongation&apos; SubClassOf &apos;cellular macromolecule biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;translational elongation&apos; SubClassOf &apos;macromolecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006417</classIRI>
<classLabel>regulation of translation</classLabel>
<deletedAxiom>&apos;regulation of translation&apos; SubClassOf &apos;regulation of cellular macromolecule biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of translation&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;regulation of translation&apos; SubClassOf &apos;regulation of macromolecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002032</classIRI>
<classLabel>hematopoietic oligopotent progenitor cell</classLabel>
<deletedAxiom>&apos;hematopoietic oligopotent progenitor cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002033</classIRI>
<classLabel>short term hematopoietic stem cell</classLabel>
<deletedAxiom>&apos;short term hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein kinase FLT3&apos;</deletedAxiom>
<deletedAxiom>&apos;short term hematopoietic stem cell&apos; EquivalentTo &apos;Kit and Sca1-positive hematopoietic stem cell&apos; and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;) and (&apos;has plasma membrane part&apos; some &apos;SLAM family member 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein kinase FLT3&apos;)</deletedAxiom>
<newAxiom>&apos;short term hematopoietic stem cell&apos; EquivalentTo &apos;Kit and Sca1-positive hematopoietic stem cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein kinase FLT3&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;) and (&apos;has plasma membrane part&apos; some &apos;SLAM family member 1&apos;)</newAxiom>
<newAxiom>&apos;short term hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein kinase FLT3&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002034</classIRI>
<classLabel>long term hematopoietic stem cell</classLabel>
<deletedAxiom>&apos;long term hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein kinase FLT3&apos;</deletedAxiom>
<deletedAxiom>&apos;long term hematopoietic stem cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD34 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;long term hematopoietic stem cell&apos; EquivalentTo &apos;Kit and Sca1-positive hematopoietic stem cell&apos; and (&apos;has plasma membrane part&apos; some &apos;SLAM family member 1&apos;) and (&apos;has low plasma membrane amount&apos; some &apos;Thy-1 membrane glycoprotein&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD34 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein kinase FLT3&apos;)</deletedAxiom>
<newAxiom>&apos;long term hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein kinase FLT3&apos;</newAxiom>
<newAxiom>&apos;long term hematopoietic stem cell&apos; EquivalentTo &apos;Kit and Sca1-positive hematopoietic stem cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD34 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein kinase FLT3&apos;) and (&apos;has plasma membrane part&apos; some &apos;SLAM family member 1&apos;) and (&apos;has low plasma membrane amount&apos; some &apos;Thy-1 membrane glycoprotein&apos;)</newAxiom>
<newAxiom>&apos;long term hematopoietic stem cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD34 molecule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002035</classIRI>
<classLabel>Slamf1-negative multipotent progenitor cell</classLabel>
<deletedAxiom>&apos;Slamf1-negative multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;SLAM family member 1&apos;</deletedAxiom>
<deletedAxiom>&apos;Slamf1-negative multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein kinase FLT3&apos;</deletedAxiom>
<deletedAxiom>&apos;Slamf1-negative multipotent progenitor cell&apos; EquivalentTo &apos;hematopoietic multipotent progenitor cell&apos; and (&apos;has plasma membrane part&apos; some &apos;mast/stem cell growth factor receptor&apos;) and (&apos;has plasma membrane part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;SLAM family member 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein kinase FLT3&apos;)</deletedAxiom>
<newAxiom>&apos;Slamf1-negative multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein kinase FLT3&apos;</newAxiom>
<newAxiom>&apos;Slamf1-negative multipotent progenitor cell&apos; EquivalentTo &apos;hematopoietic multipotent progenitor cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;SLAM family member 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein kinase FLT3&apos;) and (&apos;has plasma membrane part&apos; some &apos;mast/stem cell growth factor receptor&apos;) and (&apos;has plasma membrane part&apos; some &apos;lymphocyte antigen 6A-2/6E-1&apos;)</newAxiom>
<newAxiom>&apos;Slamf1-negative multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;SLAM family member 1&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005102</classIRI>
<classLabel>signaling receptor binding</classLabel>
<deletedAxiom>&apos;signaling receptor binding&apos; SubClassOf &apos;protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002031</classIRI>
<classLabel>hematopoietic lineage restricted progenitor cell</classLabel>
<deletedAxiom>&apos;hematopoietic lineage restricted progenitor cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002043</classIRI>
<classLabel>CD34-positive, CD38-negative multipotent progenitor cell</classLabel>
<deletedAxiom>&apos;CD34-positive, CD38-negative multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1&apos;</deletedAxiom>
<deletedAxiom>&apos;CD34-positive, CD38-negative multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;</deletedAxiom>
<deletedAxiom>&apos;CD34-positive, CD38-negative multipotent progenitor cell&apos; EquivalentTo &apos;hematopoietic multipotent progenitor cell&apos; and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;Thy-1 membrane glycoprotein&apos;)</deletedAxiom>
<deletedAxiom>&apos;CD34-positive, CD38-negative multipotent progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;Thy-1 membrane glycoprotein&apos;</deletedAxiom>
<newAxiom>&apos;CD34-positive, CD38-negative multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;Thy-1 membrane glycoprotein&apos;</newAxiom>
<newAxiom>&apos;CD34-positive, CD38-negative multipotent progenitor cell&apos; EquivalentTo &apos;hematopoietic multipotent progenitor cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;Thy-1 membrane glycoprotein&apos;) and (&apos;has plasma membrane part&apos; some &apos;CD34 molecule&apos;)</newAxiom>
<newAxiom>&apos;CD34-positive, CD38-negative multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1&apos;</newAxiom>
<newAxiom>&apos;CD34-positive, CD38-negative multipotent progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;receptor-type tyrosine-protein phosphatase C isoform CD45RA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031402</classIRI>
<classLabel>sodium ion binding</classLabel>
<deletedAxiom>&apos;sodium ion binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;sodium(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;sodium ion binding&apos; SubClassOf &apos;alkali metal ion binding&apos;</deletedAxiom>
<deletedAxiom>&apos;sodium ion binding&apos; SubClassOf &apos;has input&apos; some &apos;sodium(1+)&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031406</classIRI>
<classLabel>carboxylic acid binding</classLabel>
<deletedAxiom>&apos;carboxylic acid binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;carboxylic acid anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;carboxylic acid binding&apos; SubClassOf &apos;anion binding&apos;</deletedAxiom>
<deletedAxiom>&apos;carboxylic acid binding&apos; SubClassOf &apos;has input&apos; some &apos;carboxylic acid anion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005126</classIRI>
<classLabel>cytokine receptor binding</classLabel>
<deletedAxiom>&apos;cytokine receptor binding&apos; SubClassOf &apos;signaling receptor binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905214</classIRI>
<classLabel>regulation of RNA binding</classLabel>
<deletedAxiom>&apos;regulation of RNA binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;RNA binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of RNA binding&apos; SubClassOf &apos;regulates&apos; some &apos;RNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of RNA binding&apos; SubClassOf &apos;regulation of binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905215</classIRI>
<classLabel>negative regulation of RNA binding</classLabel>
<deletedAxiom>&apos;negative regulation of RNA binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;RNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of RNA binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;RNA binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of RNA binding&apos; SubClassOf &apos;negative regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of RNA binding&apos; SubClassOf &apos;regulation of RNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905216</classIRI>
<classLabel>positive regulation of RNA binding</classLabel>
<deletedAxiom>&apos;positive regulation of RNA binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;RNA binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of RNA binding&apos; SubClassOf &apos;regulation of RNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of RNA binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;RNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of RNA binding&apos; SubClassOf &apos;positive regulation of binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002079</classIRI>
<classLabel>pancreatic ductal cell</classLabel>
<deletedAxiom>&apos;pancreatic ductal cell&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002087</classIRI>
<classLabel>nongranular leukocyte</classLabel>
<deletedAxiom>&apos;nongranular leukocyte&apos; SubClassOf &apos;lacks_part&apos; some &apos;secretory granule&apos;</deletedAxiom>
<deletedAxiom>&apos;nongranular leukocyte&apos; EquivalentTo &apos;leukocyte&apos; and (&apos;lacks_part&apos; some &apos;secretory granule&apos;)</deletedAxiom>
<newAxiom>&apos;nongranular leukocyte&apos; EquivalentTo &apos;leukocyte&apos; and (http://purl.obolibrary.org/obo/CL_4030045 some &apos;secretory granule&apos;)</newAxiom>
<newAxiom>&apos;nongranular leukocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030045 some &apos;secretory granule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002088</classIRI>
<classLabel>interstitial cell of Cajal</classLabel>
<deletedAxiom>&apos;interstitial cell of Cajal&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031420</classIRI>
<classLabel>alkali metal ion binding</classLabel>
<deletedAxiom>&apos;alkali metal ion binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;alkali metal cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;alkali metal ion binding&apos; SubClassOf &apos;metal ion binding&apos;</deletedAxiom>
<deletedAxiom>&apos;alkali metal ion binding&apos; SubClassOf &apos;has input&apos; some &apos;alkali metal cation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002080</classIRI>
<classLabel>pancreatic centro-acinar cell</classLabel>
<deletedAxiom>&apos;pancreatic centro-acinar cell&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017148</classIRI>
<classLabel>negative regulation of translation</classLabel>
<deletedAxiom>&apos;negative regulation of translation&apos; SubClassOf &apos;negative regulation of cellular macromolecule biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of translation&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of translation&apos; SubClassOf &apos;negative regulation of macromolecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005172</classIRI>
<classLabel>vascular endothelial growth factor receptor binding</classLabel>
<deletedAxiom>&apos;vascular endothelial growth factor receptor binding&apos; SubClassOf &apos;has input&apos; some &apos;vascular endothelial growth factor receptor&apos;</deletedAxiom>
<deletedAxiom>&apos;vascular endothelial growth factor receptor binding&apos; SubClassOf &apos;cytokine receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;vascular endothelial growth factor receptor binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;vascular endothelial growth factor receptor&apos;)</deletedAxiom>
<deletedAxiom>&apos;vascular endothelial growth factor receptor binding&apos; SubClassOf &apos;growth factor receptor binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005173</classIRI>
<classLabel>stem cell factor receptor binding</classLabel>
<deletedAxiom>&apos;stem cell factor receptor binding&apos; SubClassOf &apos;has input&apos; some &apos;mast/stem cell growth factor receptor&apos;</deletedAxiom>
<deletedAxiom>&apos;stem cell factor receptor binding&apos; SubClassOf &apos;cytokine receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;stem cell factor receptor binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;mast/stem cell growth factor receptor&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043471</classIRI>
<classLabel>regulation of cellular carbohydrate catabolic process</classLabel>
<deletedAxiom>&apos;regulation of cellular carbohydrate catabolic process&apos; SubClassOf &apos;regulation of cellular carbohydrate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular carbohydrate catabolic process&apos; SubClassOf &apos;regulation of carbohydrate catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular carbohydrate catabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;cellular carbohydrate catabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular carbohydrate catabolic process&apos; SubClassOf &apos;regulates&apos; some &apos;cellular carbohydrate catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular carbohydrate catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular carbohydrate catabolic process&apos; SubClassOf &apos;regulation of macromolecule metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043393</classIRI>
<classLabel>regulation of protein binding</classLabel>
<deletedAxiom>&apos;regulation of protein binding&apos; SubClassOf &apos;regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein binding&apos; SubClassOf &apos;regulates&apos; some &apos;protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein binding&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;protein binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000312</classIRI>
<classLabel>keratinocyte</classLabel>
<deletedAxiom>&apos;keratinocyte&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000329</classIRI>
<classLabel>oxygen accumulating cell</classLabel>
<deletedAxiom>&apos;oxygen accumulating cell&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120023</classIRI>
<classLabel>somatostatin binding</classLabel>
<deletedAxiom>&apos;somatostatin binding&apos; SubClassOf &apos;peptide hormone binding&apos;</deletedAxiom>
<deletedAxiom>&apos;somatostatin binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;somatostatin&apos;)</deletedAxiom>
<deletedAxiom>&apos;somatostatin binding&apos; SubClassOf &apos;has input&apos; some &apos;somatostatin&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000349</classIRI>
<classLabel>extraembryonic cell</classLabel>
<deletedAxiom>&apos;extraembryonic cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
<deletedAxiom>&apos;extraembryonic cell&apos; SubClassOf &apos;animal cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000348</classIRI>
<classLabel>choroidal cell of the eye</classLabel>
<deletedAxiom>&apos;choroidal cell of the eye&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
<newAxiom>&apos;choroidal cell of the eye&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000347</classIRI>
<classLabel>scleral cell</classLabel>
<deletedAxiom>&apos;scleral cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
<newAxiom>&apos;scleral cell&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061102</classIRI>
<classLabel>stomach neuroendocrine cell differentiation</classLabel>
<newAxiom>&apos;stomach neuroendocrine cell differentiation&apos; SubClassOf &apos;enteroendocrine cell differentiation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006325</classIRI>
<classLabel>chromatin organization</classLabel>
<deletedAxiom>&apos;chromatin organization&apos; SubClassOf &apos;cellular component organization&apos;</deletedAxiom>
<newAxiom>&apos;chromatin organization&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0071824</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097159</classIRI>
<classLabel>organic cyclic compound binding</classLabel>
<deletedAxiom>&apos;organic cyclic compound binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;organic cyclic compound&apos;)</deletedAxiom>
<deletedAxiom>&apos;organic cyclic compound binding&apos; SubClassOf &apos;has input&apos; some &apos;organic cyclic compound&apos;</deletedAxiom>
<deletedAxiom>&apos;organic cyclic compound binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017046</classIRI>
<classLabel>peptide hormone binding</classLabel>
<deletedAxiom>&apos;peptide hormone binding&apos; SubClassOf &apos;hormone binding&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide hormone binding&apos; SubClassOf &apos;has input&apos; some &apos;peptide hormone&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide hormone binding&apos; SubClassOf &apos;peptide binding&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide hormone binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;peptide hormone&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008231</classIRI>
<classLabel>dorsal thoracic segment of trunk</classLabel>
<deletedAxiom>&apos;dorsal thoracic segment of trunk&apos; SubClassOf &apos;part of&apos; some &apos;thoracic segment of trunk&apos;</deletedAxiom>
<newAxiom>&apos;dorsal thoracic segment of trunk&apos; SubClassOf &apos;part of&apos; some &apos;thoracic segment of trunk&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070873</classIRI>
<classLabel>regulation of glycogen metabolic process</classLabel>
<deletedAxiom>&apos;regulation of glycogen metabolic process&apos; SubClassOf &apos;regulation of cellular carbohydrate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070875</classIRI>
<classLabel>positive regulation of glycogen metabolic process</classLabel>
<newAxiom>&apos;positive regulation of glycogen metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070874</classIRI>
<classLabel>negative regulation of glycogen metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of glycogen metabolic process&apos; SubClassOf &apos;negative regulation of cellular carbohydrate metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of glycogen metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of glycogen metabolic process&apos; SubClassOf &apos;negative regulation of carbohydrate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070851</classIRI>
<classLabel>growth factor receptor binding</classLabel>
<deletedAxiom>&apos;growth factor receptor binding&apos; SubClassOf &apos;signaling receptor binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000451</classIRI>
<classLabel>dendritic cell</classLabel>
<deletedAxiom>&apos;dendritic cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;</deletedAxiom>
<deletedAxiom>&apos;dendritic cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;</deletedAxiom>
<deletedAxiom>&apos;dendritic cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;dendritic cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD34 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;dendritic cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</deletedAxiom>
<deletedAxiom>&apos;dendritic cell&apos; EquivalentTo &apos;leukocyte&apos; and (&apos;has_part&apos; some &apos;MHC class II protein complex&apos;) and (&apos;bearer of&apos; some &apos;mononucleate&apos;) and (&apos;capable of&apos; some &apos;cytokine production&apos;) and (&apos;capable of&apos; some &apos;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II&apos;) and (&apos;capable of&apos; some &apos;antigen processing and presentation&apos;) and (&apos;capable of&apos; some &apos;regulation of T cell differentiation&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD34 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;)</deletedAxiom>
<newAxiom>&apos;dendritic cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;</newAxiom>
<newAxiom>&apos;dendritic cell&apos; EquivalentTo &apos;leukocyte&apos; and (&apos;has_part&apos; some &apos;MHC class II protein complex&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD34 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (&apos;bearer of&apos; some &apos;mononucleate&apos;) and (&apos;capable of&apos; some &apos;cytokine production&apos;) and (&apos;capable of&apos; some &apos;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II&apos;) and (&apos;capable of&apos; some &apos;antigen processing and presentation&apos;) and (&apos;capable of&apos; some &apos;regulation of T cell differentiation&apos;)</newAxiom>
<newAxiom>&apos;dendritic cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;</newAxiom>
<newAxiom>&apos;dendritic cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</newAxiom>
<newAxiom>&apos;dendritic cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;</newAxiom>
<newAxiom>&apos;dendritic cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD34 molecule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0011115</classIRI>
<classLabel>precursor cell</classLabel>
<deletedAxiom>&apos;precursor cell&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_2000022</classIRI>
<classLabel>cardiac septum cell</classLabel>
<deletedAxiom>&apos;cardiac septum cell&apos; SubClassOf &apos;native cell&apos;</deletedAxiom>
<deletedAxiom>&apos;cardiac septum cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
<newAxiom>&apos;cardiac septum cell&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_2000020</classIRI>
<classLabel>inner cell mass cell</classLabel>
<deletedAxiom>&apos;inner cell mass cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048029</classIRI>
<classLabel>monosaccharide binding</classLabel>
<deletedAxiom>&apos;monosaccharide binding&apos; SubClassOf &apos;small molecule binding&apos;</deletedAxiom>
<deletedAxiom>&apos;monosaccharide binding&apos; SubClassOf &apos;carbohydrate binding&apos;</deletedAxiom>
<deletedAxiom>&apos;monosaccharide binding&apos; SubClassOf &apos;has input&apos; some &apos;monosaccharide&apos;</deletedAxiom>
<deletedAxiom>&apos;monosaccharide binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;monosaccharide&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140354</classIRI>
<classLabel>lipid import into cell</classLabel>
<deletedAxiom>&apos;lipid import into cell&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
<newAxiom>&apos;lipid import into cell&apos; SubClassOf &apos;has target start location&apos; some &apos;extracellular region&apos;</newAxiom>
<newAxiom>&apos;lipid import into cell&apos; SubClassOf &apos;has target end location&apos; some &apos;intracellular anatomical structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036094</classIRI>
<classLabel>small molecule binding</classLabel>
<deletedAxiom>&apos;small molecule binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043176</classIRI>
<classLabel>amine binding</classLabel>
<deletedAxiom>&apos;amine binding&apos; SubClassOf &apos;has input&apos; some &apos;amine&apos;</deletedAxiom>
<deletedAxiom>&apos;amine binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;amine binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;amine&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043177</classIRI>
<classLabel>organic acid binding</classLabel>
<deletedAxiom>&apos;organic acid binding&apos; SubClassOf &apos;small molecule binding&apos;</deletedAxiom>
<deletedAxiom>&apos;organic acid binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;organic acid&apos;)</deletedAxiom>
<deletedAxiom>&apos;organic acid binding&apos; SubClassOf &apos;has input&apos; some &apos;organic acid&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043167</classIRI>
<classLabel>ion binding</classLabel>
<deletedAxiom>&apos;ion binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;ion binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;ion&apos;)</deletedAxiom>
<deletedAxiom>&apos;ion binding&apos; SubClassOf &apos;has input&apos; some &apos;ion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043168</classIRI>
<classLabel>anion binding</classLabel>
<deletedAxiom>&apos;anion binding&apos; SubClassOf &apos;has input&apos; some &apos;anion&apos;</deletedAxiom>
<deletedAxiom>&apos;anion binding&apos; SubClassOf &apos;ion binding&apos;</deletedAxiom>
<deletedAxiom>&apos;anion binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;anion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043169</classIRI>
<classLabel>cation binding</classLabel>
<deletedAxiom>&apos;cation binding&apos; SubClassOf &apos;has input&apos; some &apos;cation&apos;</deletedAxiom>
<deletedAxiom>&apos;cation binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;cation binding&apos; SubClassOf &apos;ion binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000542</classIRI>
<classLabel>lymphocyte</classLabel>
<newAxiom>&apos;lymphocyte&apos; SubClassOf &apos;protein-containing material entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000540</classIRI>
<classLabel>neuron</classLabel>
<deletedAxiom>&apos;neuron&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043199</classIRI>
<classLabel>sulfate binding</classLabel>
<deletedAxiom>&apos;sulfate binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;sulfate&apos;)</deletedAxiom>
<deletedAxiom>&apos;sulfate binding&apos; SubClassOf &apos;anion binding&apos;</deletedAxiom>
<deletedAxiom>&apos;sulfate binding&apos; SubClassOf &apos;has input&apos; some &apos;sulfate&apos;</deletedAxiom>
<deletedAxiom>&apos;sulfate binding&apos; SubClassOf &apos;sulfur compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000547</classIRI>
<classLabel>proerythroblast</classLabel>
<deletedAxiom>&apos;proerythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;proerythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;</deletedAxiom>
<deletedAxiom>&apos;proerythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;</deletedAxiom>
<deletedAxiom>&apos;proerythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;</deletedAxiom>
<deletedAxiom>&apos;proerythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;proerythroblast&apos; EquivalentTo &apos;erythroid lineage cell&apos; and (&apos;has_part&apos; some &apos;basophilic cytoplasm&apos;) and (&apos;has_part&apos; some &apos;increased nucleus size&apos;) and (&apos;has_part&apos; some &apos;nucleolus&apos;) and (&apos;bearer of&apos; some &apos;nucleated&apos;) and (&apos;has plasma membrane part&apos; some &apos;transferrin receptor protein 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;)</deletedAxiom>
<deletedAxiom>&apos;proerythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;proerythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;proerythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</deletedAxiom>
<deletedAxiom>&apos;proerythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</deletedAxiom>
<deletedAxiom>&apos;proerythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;</deletedAxiom>
<deletedAxiom>&apos;proerythroblast&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;</deletedAxiom>
<newAxiom>&apos;proerythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;</newAxiom>
<newAxiom>&apos;proerythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</newAxiom>
<newAxiom>&apos;proerythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;</newAxiom>
<newAxiom>&apos;proerythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;</newAxiom>
<newAxiom>&apos;proerythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;</newAxiom>
<newAxiom>&apos;proerythroblast&apos; SubClassOf &apos;protein-containing material entity&apos;</newAxiom>
<newAxiom>&apos;proerythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;</newAxiom>
<newAxiom>&apos;proerythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;</newAxiom>
<newAxiom>&apos;proerythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;</newAxiom>
<newAxiom>&apos;proerythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;</newAxiom>
<newAxiom>&apos;proerythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;</newAxiom>
<newAxiom>&apos;proerythroblast&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</newAxiom>
<newAxiom>&apos;proerythroblast&apos; EquivalentTo &apos;erythroid lineage cell&apos; and (&apos;has_part&apos; some &apos;basophilic cytoplasm&apos;) and (&apos;has_part&apos; some &apos;increased nucleus size&apos;) and (&apos;has_part&apos; some &apos;nucleolus&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;) and (&apos;bearer of&apos; some &apos;nucleated&apos;) and (&apos;has plasma membrane part&apos; some &apos;transferrin receptor protein 1&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000553</classIRI>
<classLabel>megakaryocyte progenitor cell</classLabel>
<deletedAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;</deletedAxiom>
<deletedAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</deletedAxiom>
<deletedAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;</deletedAxiom>
<deletedAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</deletedAxiom>
<deletedAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;</deletedAxiom>
<deletedAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;</deletedAxiom>
<deletedAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;</deletedAxiom>
<deletedAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;</deletedAxiom>
<deletedAxiom>&apos;megakaryocyte progenitor cell&apos; EquivalentTo &apos;myeloid lineage restricted progenitor cell&apos; and (&apos;capable of&apos; some &apos;endomitotic cell cycle&apos;) and (&apos;capable of&apos; some &apos;megakaryocyte differentiation&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 76 (mouse)&apos;)</deletedAxiom>
<newAxiom>&apos;megakaryocyte progenitor cell&apos; EquivalentTo &apos;myeloid lineage restricted progenitor cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 76 (mouse)&apos;) and (&apos;capable of&apos; some &apos;endomitotic cell cycle&apos;) and (&apos;capable of&apos; some &apos;megakaryocyte differentiation&apos;)</newAxiom>
<newAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;</newAxiom>
<newAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;</newAxiom>
<newAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;</newAxiom>
<newAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;</newAxiom>
<newAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</newAxiom>
<newAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</newAxiom>
<newAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 76 (mouse)&apos;</newAxiom>
<newAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;</newAxiom>
<newAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;</newAxiom>
<newAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;</newAxiom>
<newAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;</newAxiom>
<newAxiom>&apos;megakaryocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043184</classIRI>
<classLabel>vascular endothelial growth factor receptor 2 binding</classLabel>
<deletedAxiom>&apos;vascular endothelial growth factor receptor 2 binding&apos; SubClassOf &apos;vascular endothelial growth factor receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;vascular endothelial growth factor receptor 2 binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;vascular endothelial growth factor receptor 2&apos;)</deletedAxiom>
<deletedAxiom>&apos;vascular endothelial growth factor receptor 2 binding&apos; SubClassOf &apos;has input&apos; some &apos;vascular endothelial growth factor receptor 2&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000558</classIRI>
<classLabel>reticulocyte</classLabel>
<deletedAxiom>&apos;reticulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</deletedAxiom>
<deletedAxiom>&apos;reticulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;</deletedAxiom>
<deletedAxiom>&apos;reticulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;</deletedAxiom>
<deletedAxiom>&apos;reticulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;</deletedAxiom>
<deletedAxiom>&apos;reticulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;reticulocyte&apos; EquivalentTo &apos;erythroid lineage cell&apos; and (&apos;has plasma membrane part&apos; some &apos;transferrin receptor protein 1&apos;) and (&apos;capable of&apos; some &apos;extracellular exosome assembly&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD4 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD3 epsilon&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;neural cell adhesion molecule 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;T-cell surface glycoprotein CD5&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;) and (&apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;)</deletedAxiom>
<deletedAxiom>&apos;reticulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;integrin alpha-M&apos;</deletedAxiom>
<deletedAxiom>&apos;reticulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD19 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;reticulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;lymphocyte antigen 6G&apos;</deletedAxiom>
<deletedAxiom>&apos;reticulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</deletedAxiom>
<deletedAxiom>&apos;reticulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD2 molecule&apos;</deletedAxiom>
<deletedAxiom>&apos;reticulocyte&apos; SubClassOf &apos;lacks_plasma_membrane_part&apos; some &apos;CD14 molecule&apos;</deletedAxiom>
<newAxiom>&apos;reticulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;</newAxiom>
<newAxiom>&apos;reticulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;</newAxiom>
<newAxiom>&apos;reticulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;</newAxiom>
<newAxiom>&apos;reticulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;</newAxiom>
<newAxiom>&apos;reticulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;</newAxiom>
<newAxiom>&apos;reticulocyte&apos; EquivalentTo &apos;erythroid lineage cell&apos; and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD19 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;neural cell adhesion molecule 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;membrane-spanning 4-domains subfamily A member 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD5&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;) and (http://purl.obolibrary.org/obo/CL_4030046 some &apos;lymphocyte antigen 6G&apos;) and (&apos;has plasma membrane part&apos; some &apos;transferrin receptor protein 1&apos;) and (&apos;capable of&apos; some &apos;extracellular exosome assembly&apos;)</newAxiom>
<newAxiom>&apos;reticulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD14 molecule&apos;</newAxiom>
<newAxiom>&apos;reticulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;integrin alpha-M&apos;</newAxiom>
<newAxiom>&apos;reticulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD3 epsilon&apos;</newAxiom>
<newAxiom>&apos;reticulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD2 molecule&apos;</newAxiom>
<newAxiom>&apos;reticulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;T-cell surface glycoprotein CD8 alpha chain&apos;</newAxiom>
<newAxiom>&apos;reticulocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030046 some &apos;CD4 molecule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000557</classIRI>
<classLabel>granulocyte monocyte progenitor cell</classLabel>
<deletedAxiom>&apos;granulocyte monocyte progenitor cell&apos; SubClassOf &apos;lacks_part&apos; some &apos;erythroid transcription factor&apos;</deletedAxiom>
<deletedAxiom>&apos;granulocyte monocyte progenitor cell&apos; EquivalentTo &apos;hematopoietic oligopotent progenitor cell&apos; and (&apos;part of&apos; some &apos;bone marrow&apos;) and (&apos;has_part&apos; some &apos;transcription factor PU.1&apos;) and (&apos;has_part&apos; some &apos;CCAAT/enhancer-binding protein alpha&apos;) and (&apos;has plasma membrane part&apos; some &apos;interleukin-3 receptor class 2 alpha chain&apos;) and (&apos;capable of&apos; some &apos;macrophage differentiation&apos;) and (&apos;capable of&apos; some &apos;granulocyte differentiation&apos;) and (&apos;lacks_part&apos; some &apos;erythroid transcription factor&apos;) and (&apos;lacks_part&apos; some &apos;endothelial transcription factor GATA-2&apos;)</deletedAxiom>
<deletedAxiom>&apos;granulocyte monocyte progenitor cell&apos; SubClassOf &apos;lacks_part&apos; some &apos;endothelial transcription factor GATA-2&apos;</deletedAxiom>
<newAxiom>&apos;granulocyte monocyte progenitor cell&apos; EquivalentTo &apos;hematopoietic oligopotent progenitor cell&apos; and (&apos;part of&apos; some &apos;bone marrow&apos;) and (&apos;has_part&apos; some &apos;transcription factor PU.1&apos;) and (&apos;has_part&apos; some &apos;CCAAT/enhancer-binding protein alpha&apos;) and (http://purl.obolibrary.org/obo/CL_4030045 some &apos;erythroid transcription factor&apos;) and (http://purl.obolibrary.org/obo/CL_4030045 some &apos;endothelial transcription factor GATA-2&apos;) and (&apos;has plasma membrane part&apos; some &apos;interleukin-3 receptor class 2 alpha chain&apos;) and (&apos;capable of&apos; some &apos;macrophage differentiation&apos;) and (&apos;capable of&apos; some &apos;granulocyte differentiation&apos;)</newAxiom>
<newAxiom>&apos;granulocyte monocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030045 some &apos;erythroid transcription factor&apos;</newAxiom>
<newAxiom>&apos;granulocyte monocyte progenitor cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030045 some &apos;endothelial transcription factor GATA-2&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000556</classIRI>
<classLabel>megakaryocyte</classLabel>
<deletedAxiom>&apos;megakaryocyte&apos; EquivalentTo &apos;myeloid cell&apos; and (&apos;part of&apos; some &apos;bone marrow&apos;) and (&apos;bearer of&apos; some &apos;euploid&apos;)</deletedAxiom>
<deletedAxiom>&apos;megakaryocyte&apos; SubClassOf &apos;bone marrow hematopoietic cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000564</classIRI>
<classLabel>neutrophilic promyelocyte</classLabel>
<deletedAxiom>&apos;neutrophilic promyelocyte&apos; SubClassOf &apos;lacks_part&apos; some &apos;lactotransferrin&apos;</deletedAxiom>
<deletedAxiom>&apos;neutrophilic promyelocyte&apos; EquivalentTo &apos;promyelocyte&apos; and (&apos;has_part&apos; some &apos;transcription factor PU.1&apos;) and (&apos;has_part&apos; some &apos;CCAAT/enhancer-binding protein alpha&apos;) and (&apos;has_part&apos; some &apos;erythroid transcription factor&apos;) and (&apos;has_part&apos; some &apos;myeloperoxidase&apos;) and (&apos;has_part&apos; some &apos;runt-related transcription factor 1&apos;) and (&apos;capable of&apos; some &apos;neutrophil differentiation&apos;) and (&apos;lacks_part&apos; some &apos;lactotransferrin&apos;)</deletedAxiom>
<newAxiom>&apos;neutrophilic promyelocyte&apos; EquivalentTo &apos;promyelocyte&apos; and (&apos;has_part&apos; some &apos;transcription factor PU.1&apos;) and (&apos;has_part&apos; some &apos;CCAAT/enhancer-binding protein alpha&apos;) and (&apos;has_part&apos; some &apos;erythroid transcription factor&apos;) and (&apos;has_part&apos; some &apos;myeloperoxidase&apos;) and (&apos;has_part&apos; some &apos;runt-related transcription factor 1&apos;) and (http://purl.obolibrary.org/obo/CL_4030045 some &apos;lactotransferrin&apos;) and (&apos;capable of&apos; some &apos;neutrophil differentiation&apos;)</newAxiom>
<newAxiom>&apos;neutrophilic promyelocyte&apos; SubClassOf http://purl.obolibrary.org/obo/CL_4030045 some &apos;lactotransferrin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0016458</classIRI>
<classLabel>esophageal hiatus</classLabel>
<deletedAxiom>&apos;esophageal hiatus&apos; SubClassOf &apos;conduit for&apos; some &apos;esophagus&apos;</deletedAxiom>
<deletedAxiom>&apos;esophageal hiatus&apos; EquivalentTo &apos;orifice&apos; and (&apos;part of&apos; some &apos;diaphragm&apos;) and (&apos;conduit for&apos; some &apos;esophagus&apos;)</deletedAxiom>
<newAxiom>&apos;esophageal hiatus&apos; EquivalentTo &apos;orifice&apos; and (&apos;part of&apos; some &apos;diaphragm&apos;) and (http://purl.obolibrary.org/obo/RO_0002570 some &apos;esophagus&apos;)</newAxiom>
<newAxiom>&apos;esophageal hiatus&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002570 some &apos;esophagus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051630</classIRI>
<classLabel>acetylcholine uptake</classLabel>
<deletedAxiom>&apos;acetylcholine uptake&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
<newAxiom>&apos;acetylcholine uptake&apos; SubClassOf &apos;has target start location&apos; some &apos;extracellular region&apos;</newAxiom>
<newAxiom>&apos;acetylcholine uptake&apos; SubClassOf &apos;has target end location&apos; some &apos;intracellular anatomical structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140297</classIRI>
<classLabel>DNA-binding transcription factor binding</classLabel>
<deletedAxiom>&apos;DNA-binding transcription factor binding&apos; SubClassOf &apos;transcription factor binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990239</classIRI>
<classLabel>steroid hormone binding</classLabel>
<deletedAxiom>&apos;steroid hormone binding&apos; SubClassOf &apos;steroid binding&apos;</deletedAxiom>
<deletedAxiom>&apos;steroid hormone binding&apos; SubClassOf &apos;hormone binding&apos;</deletedAxiom>
<deletedAxiom>&apos;steroid hormone binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;steroid hormone&apos;)</deletedAxiom>
<deletedAxiom>&apos;steroid hormone binding&apos; SubClassOf &apos;has input&apos; some &apos;steroid hormone&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000035</classIRI>
<classLabel>acyl binding</classLabel>
<deletedAxiom>&apos;acyl binding&apos; SubClassOf &apos;has input&apos; some &apos;acyl group&apos;</deletedAxiom>
<deletedAxiom>&apos;acyl binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;acyl binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;acyl group&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990188</classIRI>
<classLabel>euchromatin binding</classLabel>
<deletedAxiom>&apos;euchromatin binding&apos; SubClassOf &apos;chromatin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;euchromatin binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;euchromatin&apos;)</deletedAxiom>
<deletedAxiom>&apos;euchromatin binding&apos; SubClassOf &apos;has input&apos; some &apos;euchromatin&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045721</classIRI>
<classLabel>negative regulation of gluconeogenesis</classLabel>
<deletedAxiom>&apos;negative regulation of gluconeogenesis&apos; SubClassOf &apos;negative regulation of cellular carbohydrate metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of gluconeogenesis&apos; SubClassOf &apos;negative regulation of carbohydrate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045719</classIRI>
<classLabel>negative regulation of glycogen biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of glycogen biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular macromolecule biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of glycogen biosynthetic process&apos; SubClassOf &apos;negative regulation of macromolecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0035639</classIRI>
<classLabel>ocular adnexa</classLabel>
<deletedAxiom>&apos;ocular adnexa&apos; SubClassOf &apos;anatomical cluster&apos;</deletedAxiom>
<newAxiom>&apos;ocular adnexa&apos; SubClassOf &apos;multi organ part structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099536</classIRI>
<classLabel>synaptic signaling</classLabel>
<deletedAxiom>&apos;synaptic signaling&apos; DisjointWith &apos;in taxon&apos; some &apos;Schizosaccharomyces&apos;</deletedAxiom>
<deletedAxiom>&apos;synaptic signaling&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Schizosaccharomyces&apos;)</deletedAxiom>
<deletedAxiom>&apos;synaptic signaling&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Schizosaccharomyces&apos;))</deletedAxiom>
<newAxiom>&apos;synaptic signaling&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;synaptic signaling&apos; SubClassOf &apos;only in taxon&apos; some &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099550</classIRI>
<classLabel>trans-synaptic signaling, modulating synaptic transmission</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling, modulating synaptic transmission&apos; SubClassOf &apos;regulates&apos; some &apos;chemical synaptic transmission&apos;</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling, modulating synaptic transmission&apos; SubClassOf &apos;modulation of chemical synaptic transmission&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006073</classIRI>
<classLabel>cellular glucan metabolic process</classLabel>
<deletedAxiom>&apos;cellular glucan metabolic process&apos; SubClassOf &apos;cellular polysaccharide metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular glucan metabolic process&apos; SubClassOf &apos;glucan metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033692</classIRI>
<classLabel>cellular polysaccharide biosynthetic process</classLabel>
<deletedAxiom>&apos;cellular polysaccharide biosynthetic process&apos; SubClassOf &apos;polysaccharide biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular polysaccharide biosynthetic process&apos; SubClassOf &apos;cellular macromolecule biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular polysaccharide biosynthetic process&apos; SubClassOf &apos;cellular carbohydrate biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular polysaccharide biosynthetic process&apos; SubClassOf &apos;cellular polysaccharide metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043021</classIRI>
<classLabel>ribonucleoprotein complex binding</classLabel>
<deletedAxiom>&apos;ribonucleoprotein complex binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;ribonucleoprotein complex&apos;)</deletedAxiom>
<deletedAxiom>&apos;ribonucleoprotein complex binding&apos; SubClassOf &apos;has input&apos; some &apos;ribonucleoprotein complex&apos;</deletedAxiom>
<deletedAxiom>&apos;ribonucleoprotein complex binding&apos; SubClassOf &apos;protein-containing complex binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043022</classIRI>
<classLabel>ribosome binding</classLabel>
<deletedAxiom>&apos;ribosome binding&apos; SubClassOf &apos;has input&apos; some &apos;ribosome&apos;</deletedAxiom>
<deletedAxiom>&apos;ribosome binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;ribosome&apos;)</deletedAxiom>
<deletedAxiom>&apos;ribosome binding&apos; SubClassOf &apos;ribonucleoprotein complex binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000670</classIRI>
<classLabel>primordial germ cell</classLabel>
<newAxiom>&apos;primordial germ cell&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0009001</classIRI>
<classLabel>compound eye retinal cell</classLabel>
<deletedAxiom>&apos;compound eye retinal cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
<deletedAxiom>&apos;compound eye retinal cell&apos; SubClassOf &apos;somatic cell&apos;</deletedAxiom>
<newAxiom>&apos;compound eye retinal cell&apos; SubClassOf &apos;retinal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043067</classIRI>
<classLabel>regulation of programmed cell death</classLabel>
<deletedAxiom>&apos;regulation of programmed cell death&apos; SubClassOf &apos;regulation of cell death&apos;</deletedAxiom>
<newAxiom>&apos;regulation of programmed cell death&apos; SubClassOf &apos;regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043068</classIRI>
<classLabel>positive regulation of programmed cell death</classLabel>
<deletedAxiom>&apos;positive regulation of programmed cell death&apos; SubClassOf &apos;positive regulation of cell death&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of programmed cell death&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043069</classIRI>
<classLabel>negative regulation of programmed cell death</classLabel>
<deletedAxiom>&apos;negative regulation of programmed cell death&apos; SubClassOf &apos;negative regulation of cell death&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of programmed cell death&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0010007</classIRI>
<classLabel>His-Purkinje system cell</classLabel>
<deletedAxiom>&apos;His-Purkinje system cell&apos; SubClassOf &apos;native cell&apos;</deletedAxiom>
<deletedAxiom>&apos;His-Purkinje system cell&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
<newAxiom>&apos;His-Purkinje system cell&apos; SubClassOf &apos;animal cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055072</classIRI>
<classLabel>iron ion homeostasis</classLabel>
<deletedAxiom>&apos;iron ion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;iron cation&apos;</deletedAxiom>
<deletedAxiom>&apos;iron ion homeostasis&apos; SubClassOf &apos;monoatomic cation homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;iron ion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;iron ion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;iron cation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010906</classIRI>
<classLabel>regulation of glucose metabolic process</classLabel>
<deletedAxiom>&apos;regulation of glucose metabolic process&apos; SubClassOf &apos;regulation of cellular carbohydrate metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of glucose metabolic process&apos; SubClassOf &apos;regulation of carbohydrate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010907</classIRI>
<classLabel>positive regulation of glucose metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of glucose metabolic process&apos; SubClassOf &apos;positive regulation of cellular carbohydrate metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of glucose metabolic process&apos; SubClassOf &apos;positive regulation of carbohydrate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010941</classIRI>
<classLabel>regulation of cell death</classLabel>
<deletedAxiom>&apos;regulation of cell death&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;cell death&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cell death&apos; SubClassOf &apos;regulates&apos; some &apos;cell death&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cell death&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010942</classIRI>
<classLabel>positive regulation of cell death</classLabel>
<deletedAxiom>&apos;positive regulation of cell death&apos; SubClassOf &apos;positively regulates&apos; some &apos;cell death&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cell death&apos; SubClassOf &apos;regulation of cell death&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cell death&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;cell death&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cell death&apos; SubClassOf &apos;positive regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003061</classIRI>
<classLabel>blood island</classLabel>
<deletedAxiom>&apos;blood island&apos; SubClassOf &apos;contains process&apos; some &apos;hemopoiesis&apos;</deletedAxiom>
<deletedAxiom>&apos;blood island&apos; SubClassOf &apos;contains process&apos; some &apos;angiogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010962</classIRI>
<classLabel>regulation of glucan biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of glucan biosynthetic process&apos; SubClassOf &apos;regulation of cellular macromolecule biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of glucan biosynthetic process&apos; SubClassOf &apos;regulation of cellular carbohydrate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046914</classIRI>
<classLabel>transition metal ion binding</classLabel>
<deletedAxiom>&apos;transition metal ion binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;transition element cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;transition metal ion binding&apos; SubClassOf &apos;has input&apos; some &apos;transition element cation&apos;</deletedAxiom>
<deletedAxiom>&apos;transition metal ion binding&apos; SubClassOf &apos;metal ion binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046906</classIRI>
<classLabel>tetrapyrrole binding</classLabel>
<deletedAxiom>&apos;tetrapyrrole binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
<deletedAxiom>&apos;tetrapyrrole binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;tetrapyrrole&apos;)</deletedAxiom>
<deletedAxiom>&apos;tetrapyrrole binding&apos; SubClassOf &apos;organic cyclic compound binding&apos;</deletedAxiom>
<deletedAxiom>&apos;tetrapyrrole binding&apos; SubClassOf &apos;has input&apos; some &apos;tetrapyrrole&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903019</classIRI>
<classLabel>negative regulation of glycoprotein metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of glycoprotein metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903018</classIRI>
<classLabel>regulation of glycoprotein metabolic process</classLabel>
<deletedAxiom>&apos;regulation of glycoprotein metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903020</classIRI>
<classLabel>positive regulation of glycoprotein metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of glycoprotein metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071824</classIRI>
<classLabel>protein-DNA complex organization</classLabel>
<newAxiom>'protein-DNA complex organization' SubClassOf 'protein-containing complex organization'</newAxiom>
<newAxiom>'protein-DNA complex organization' SubClassOf 'results in organization of' some 'protein-DNA complex'</newAxiom>
<newAxiom>'protein-DNA complex organization' EquivalentTo 'cellular component organization' and ('results in organization of' some 'protein-DNA complex')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140097</classIRI>
<classLabel>catalytic activity, acting on DNA</classLabel>
<newAxiom>'catalytic activity, acting on DNA' SubClassOf 'has input' some 'deoxyribonucleic acid'</newAxiom>
<newAxiom>'catalytic activity, acting on DNA' SubClassOf 'catalytic activity, acting on a nucleic acid'</newAxiom>
<newAxiom>'catalytic activity, acting on DNA' EquivalentTo 'catalytic activity' and ('has input' some 'deoxyribonucleic acid')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071897</classIRI>
<classLabel>DNA biosynthetic process</classLabel>
<newAxiom>'DNA biosynthetic process' EquivalentTo 'biosynthetic process' and ('has primary output' some 'deoxyribonucleic acid')</newAxiom>
<newAxiom>'DNA biosynthetic process' SubClassOf 'nucleobase-containing compound biosynthetic process'</newAxiom>
<newAxiom>'DNA biosynthetic process' SubClassOf 'DNA metabolic process'</newAxiom>
<newAxiom>'DNA biosynthetic process' SubClassOf 'has primary output' some 'deoxyribonucleic acid'</newAxiom>
<newAxiom>'DNA biosynthetic process' SubClassOf 'macromolecule biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051336</classIRI>
<classLabel>regulation of hydrolase activity</classLabel>
<newAxiom>'regulation of hydrolase activity' SubClassOf 'regulation of catalytic activity'</newAxiom>
<newAxiom>'regulation of hydrolase activity' EquivalentTo 'biological regulation' and ('regulates' some 'hydrolase activity')</newAxiom>
<newAxiom>'regulation of hydrolase activity' SubClassOf 'regulates' some 'hydrolase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051346</classIRI>
<classLabel>negative regulation of hydrolase activity</classLabel>
<newAxiom>'negative regulation of hydrolase activity' EquivalentTo 'biological regulation' and ('negatively regulates' some 'hydrolase activity')</newAxiom>
<newAxiom>'negative regulation of hydrolase activity' SubClassOf 'negatively regulates' some 'hydrolase activity'</newAxiom>
<newAxiom>'negative regulation of hydrolase activity' SubClassOf 'negative regulation of catalytic activity'</newAxiom>
<newAxiom>'negative regulation of hydrolase activity' SubClassOf 'regulation of hydrolase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051345</classIRI>
<classLabel>positive regulation of hydrolase activity</classLabel>
<newAxiom>'positive regulation of hydrolase activity' EquivalentTo 'biological regulation' and ('positively regulates' some 'hydrolase activity')</newAxiom>
<newAxiom>'positive regulation of hydrolase activity' SubClassOf 'regulation of hydrolase activity'</newAxiom>
<newAxiom>'positive regulation of hydrolase activity' SubClassOf 'positive regulation of catalytic activity'</newAxiom>
<newAxiom>'positive regulation of hydrolase activity' SubClassOf 'positively regulates' some 'hydrolase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021523</classIRI>
<classLabel>somatic motor neuron differentiation</classLabel>
<newAxiom>'somatic motor neuron differentiation' SubClassOf 'spinal cord motor neuron differentiation'</newAxiom>
<newAxiom>'somatic motor neuron differentiation' SubClassOf 'results in acquisition of features of' some 'somatomotor neuron'</newAxiom>
<newAxiom>'somatic motor neuron differentiation' EquivalentTo 'cell differentiation' and ('results in acquisition of features of' some 'somatomotor neuron')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_4033018</classIRI>
<classLabel>lung megakaryocyte</classLabel>
<newAxiom>'lung megakaryocyte' SubClassOf 'megakaryocyte'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_4033017</classIRI>
<classLabel>bronchiolar smooth muscle cell</classLabel>
<newAxiom>'bronchiolar smooth muscle cell' SubClassOf 'part of' some 'bronchiole'</newAxiom>
<newAxiom>'bronchiolar smooth muscle cell' EquivalentTo 'smooth muscle cell' and ('part of' some 'bronchiole')</newAxiom>
<newAxiom>'bronchiolar smooth muscle cell' SubClassOf 'tracheobronchial smooth muscle cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_16733</classIRI>
<classLabel>D-alpha-amino acid</classLabel>
<newAxiom>'D-alpha-amino acid' SubClassOf http://purl.obolibrary.org/obo/chebi#is_tautomer_of some 'D-alpha-amino acid zwitterion'</newAxiom>
<newAxiom>'D-alpha-amino acid' SubClassOf 'non-proteinogenic alpha-amino acid'</newAxiom>
<newAxiom>'D-alpha-amino acid' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of some 'D-alpha-amino acid anion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_4033022</classIRI>
<classLabel>mucus secreting cell of bronchus submucosal gland</classLabel>
<newAxiom>'mucus secreting cell of bronchus submucosal gland' EquivalentTo 'mucus secreting cell' and ('part of' some 'bronchus submucosal gland')</newAxiom>
<newAxiom>'mucus secreting cell of bronchus submucosal gland' SubClassOf 'exocrine cell'</newAxiom>
<newAxiom>'mucus secreting cell of bronchus submucosal gland' SubClassOf 'mucus secreting cell'</newAxiom>
<newAxiom>'mucus secreting cell of bronchus submucosal gland' SubClassOf 'part of' some 'bronchus submucosal gland'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_4033020</classIRI>
<classLabel>mucus secreting cell of trachea gland</classLabel>
<newAxiom>'mucus secreting cell of trachea gland' EquivalentTo 'mucus secreting cell' and ('part of' some 'trachea gland')</newAxiom>
<newAxiom>'mucus secreting cell of trachea gland' SubClassOf 'mucus secreting cell'</newAxiom>
<newAxiom>'mucus secreting cell of trachea gland' SubClassOf 'exocrine cell'</newAxiom>
<newAxiom>'mucus secreting cell of trachea gland' SubClassOf 'part of' some 'trachea gland'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_60895</classIRI>
<classLabel>D-alpha-amino acid anion</classLabel>
<newAxiom>'D-alpha-amino acid anion' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of some 'D-alpha-amino acid'</newAxiom>
<newAxiom>'D-alpha-amino acid anion' SubClassOf 'alpha-amino-acid anion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032069</classIRI>
<classLabel>regulation of nuclease activity</classLabel>
<newAxiom>'regulation of nuclease activity' EquivalentTo 'biological regulation' and ('regulates' some 'nuclease activity')</newAxiom>
<newAxiom>'regulation of nuclease activity' SubClassOf 'regulation of macromolecule metabolic process'</newAxiom>
<newAxiom>'regulation of nuclease activity' SubClassOf 'regulates' some 'nuclease activity'</newAxiom>
<newAxiom>'regulation of nuclease activity' SubClassOf 'regulation of hydrolase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_83925</classIRI>
<classLabel>non-proteinogenic alpha-amino acid</classLabel>
<newAxiom>'non-proteinogenic alpha-amino acid' SubClassOf 'non-proteinogenic amino acid'</newAxiom>
<newAxiom>'non-proteinogenic alpha-amino acid' SubClassOf 'alpha-amino acid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032075</classIRI>
<classLabel>positive regulation of nuclease activity</classLabel>
<newAxiom>'positive regulation of nuclease activity' EquivalentTo 'biological regulation' and ('positively regulates' some 'nuclease activity')</newAxiom>
<newAxiom>'positive regulation of nuclease activity' SubClassOf 'positive regulation of nucleobase-containing compound metabolic process'</newAxiom>
<newAxiom>'positive regulation of nuclease activity' SubClassOf 'positively regulates' some 'nuclease activity'</newAxiom>
<newAxiom>'positive regulation of nuclease activity' SubClassOf 'regulation of nuclease activity'</newAxiom>
<newAxiom>'positive regulation of nuclease activity' SubClassOf 'positive regulation of hydrolase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032074</classIRI>
<classLabel>negative regulation of nuclease activity</classLabel>
<newAxiom>'negative regulation of nuclease activity' SubClassOf 'negatively regulates' some 'nuclease activity'</newAxiom>
<newAxiom>'negative regulation of nuclease activity' SubClassOf 'negative regulation of hydrolase activity'</newAxiom>
<newAxiom>'negative regulation of nuclease activity' SubClassOf 'negative regulation of nucleobase-containing compound metabolic process'</newAxiom>
<newAxiom>'negative regulation of nuclease activity' SubClassOf 'regulation of nuclease activity'</newAxiom>
<newAxiom>'negative regulation of nuclease activity' EquivalentTo 'biological regulation' and ('negatively regulates' some 'nuclease activity')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032077</classIRI>
<classLabel>positive regulation of deoxyribonuclease activity</classLabel>
<newAxiom>'positive regulation of deoxyribonuclease activity' SubClassOf 'positively regulates' some 'DNA nuclease activity'</newAxiom>
<newAxiom>'positive regulation of deoxyribonuclease activity' SubClassOf 'positive regulation of nuclease activity'</newAxiom>
<newAxiom>'positive regulation of deoxyribonuclease activity' EquivalentTo 'biological regulation' and ('positively regulates' some 'DNA nuclease activity')</newAxiom>
<newAxiom>'positive regulation of deoxyribonuclease activity' SubClassOf 'positive regulation of DNA metabolic process'</newAxiom>
<newAxiom>'positive regulation of deoxyribonuclease activity' SubClassOf 'regulation of deoxyribonuclease activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032076</classIRI>
<classLabel>negative regulation of deoxyribonuclease activity</classLabel>
<newAxiom>'negative regulation of deoxyribonuclease activity' SubClassOf 'regulation of deoxyribonuclease activity'</newAxiom>
<newAxiom>'negative regulation of deoxyribonuclease activity' SubClassOf 'negative regulation of nuclease activity'</newAxiom>
<newAxiom>'negative regulation of deoxyribonuclease activity' SubClassOf 'negative regulation of DNA metabolic process'</newAxiom>
<newAxiom>'negative regulation of deoxyribonuclease activity' SubClassOf 'negatively regulates' some 'DNA nuclease activity'</newAxiom>
<newAxiom>'negative regulation of deoxyribonuclease activity' EquivalentTo 'biological regulation' and ('negatively regulates' some 'DNA nuclease activity')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032070</classIRI>
<classLabel>regulation of deoxyribonuclease activity</classLabel>
<newAxiom>'regulation of deoxyribonuclease activity' EquivalentTo 'biological regulation' and ('regulates' some 'DNA nuclease activity')</newAxiom>
<newAxiom>'regulation of deoxyribonuclease activity' SubClassOf 'regulation of nuclease activity'</newAxiom>
<newAxiom>'regulation of deoxyribonuclease activity' SubClassOf 'regulates' some 'DNA nuclease activity'</newAxiom>
<newAxiom>'regulation of deoxyribonuclease activity' SubClassOf 'regulation of DNA metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902065</classIRI>
<classLabel>response to L-glutamate</classLabel>
<newAxiom>'response to L-glutamate' EquivalentTo 'response to stimulus' and ('has input' some 'L-glutamate(1-)')</newAxiom>
<newAxiom>'response to L-glutamate' SubClassOf 'response to organonitrogen compound'</newAxiom>
<newAxiom>'response to L-glutamate' SubClassOf 'has input' some 'L-glutamate(1-)'</newAxiom>
<newAxiom>'response to L-glutamate' SubClassOf 'response to oxygen-containing compound'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0005024</classIRI>
<classLabel>somatomotor neuron</classLabel>
<newAxiom>'somatomotor neuron' EquivalentTo 'motor neuron' and ('synapsed to' some 'skeletal muscle fiber')</newAxiom>
<newAxiom>'somatomotor neuron' SubClassOf 'motor neuron'</newAxiom>
<newAxiom>'somatomotor neuron' SubClassOf 'cholinergic neuron'</newAxiom>
<newAxiom>'somatomotor neuron' SubClassOf 'synapsed to' some 'skeletal muscle fiber'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_173085</classIRI>
<classLabel>ferroptosis inducer</classLabel>
<newAxiom>'ferroptosis inducer' SubClassOf 'biochemical role'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_83820</classIRI>
<classLabel>non-proteinogenic amino acid</classLabel>
<newAxiom>'non-proteinogenic amino acid' SubClassOf 'amino acid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_16991</classIRI>
<classLabel>deoxyribonucleic acid</classLabel>
<newAxiom>'deoxyribonucleic acid' SubClassOf 'nucleic acid'</newAxiom>
<newAxiom>'deoxyribonucleic acid' SubClassOf 'has_part' some 'canonical deoxyribonucleoside residue'</newAxiom>
<newAxiom>'deoxyribonucleic acid' SubClassOf 'has_part' some 'canonical deoxyribonucleotide residue'</newAxiom>
<newAxiom>'deoxyribonucleic acid' SubClassOf 'has role' some 'human metabolite'</newAxiom>
<newAxiom>'deoxyribonucleic acid' SubClassOf 'has role' some 'mouse metabolite'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003361</classIRI>
<classLabel>noradrenergic neuron differentiation involved in brainstem development</classLabel>
<newAxiom>'noradrenergic neuron differentiation involved in brainstem development' EquivalentTo 'noradrenergic neuron differentiation' and ('part of' some 'brainstem development')</newAxiom>
<newAxiom>'noradrenergic neuron differentiation involved in brainstem development' SubClassOf 'noradrenergic neuron differentiation'</newAxiom>
<newAxiom>'noradrenergic neuron differentiation involved in brainstem development' SubClassOf 'part of' some 'brainstem development'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016788</classIRI>
<classLabel>hydrolase activity, acting on ester bonds</classLabel>
<newAxiom>'hydrolase activity, acting on ester bonds' SubClassOf 'hydrolase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016787</classIRI>
<classLabel>hydrolase activity</classLabel>
<newAxiom>'hydrolase activity' SubClassOf 'catalytic activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042943</classIRI>
<classLabel>D-amino acid transmembrane transporter activity</classLabel>
<newAxiom>'D-amino acid transmembrane transporter activity' SubClassOf 'transmembrane transporter activity'</newAxiom>
<newAxiom>'D-amino acid transmembrane transporter activity' EquivalentTo 'transmembrane transporter activity' and ('has primary input' some 'D-alpha-amino acid zwitterion')</newAxiom>
<newAxiom>'D-amino acid transmembrane transporter activity' SubClassOf 'has primary input' some 'D-alpha-amino acid zwitterion'</newAxiom>
<newAxiom>'D-amino acid transmembrane transporter activity' SubClassOf 'part of' some 'D-amino acid transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042940</classIRI>
<classLabel>D-amino acid transport</classLabel>
<newAxiom>'D-amino acid transport' EquivalentTo 'transport' and ('has primary input' some 'D-alpha-amino acid zwitterion')</newAxiom>
<newAxiom>'D-amino acid transport' SubClassOf 'organic substance transport'</newAxiom>
<newAxiom>'D-amino acid transport' SubClassOf 'has primary input' some 'D-alpha-amino acid zwitterion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051035</classIRI>
<classLabel>DNA transmembrane transporter activity</classLabel>
<newAxiom>'DNA transmembrane transporter activity' SubClassOf 'has primary input' some 'deoxyribonucleic acid'</newAxiom>
<newAxiom>'DNA transmembrane transporter activity' EquivalentTo 'transmembrane transporter activity' and ('has primary input' some 'deoxyribonucleic acid')</newAxiom>
<newAxiom>'DNA transmembrane transporter activity' SubClassOf 'part of' some 'DNA transport'</newAxiom>
<newAxiom>'DNA transmembrane transporter activity' SubClassOf 'nucleic acid transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051054</classIRI>
<classLabel>positive regulation of DNA metabolic process</classLabel>
<newAxiom>'positive regulation of DNA metabolic process' SubClassOf 'positive regulation of nucleobase-containing compound metabolic process'</newAxiom>
<newAxiom>'positive regulation of DNA metabolic process' SubClassOf 'regulation of DNA metabolic process'</newAxiom>
<newAxiom>'positive regulation of DNA metabolic process' SubClassOf 'positively regulates' some 'DNA metabolic process'</newAxiom>
<newAxiom>'positive regulation of DNA metabolic process' SubClassOf 'positive regulation of macromolecule metabolic process'</newAxiom>
<newAxiom>'positive regulation of DNA metabolic process' EquivalentTo 'biological regulation' and ('positively regulates' some 'DNA metabolic process')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051053</classIRI>
<classLabel>negative regulation of DNA metabolic process</classLabel>
<newAxiom>'negative regulation of DNA metabolic process' SubClassOf 'regulation of DNA metabolic process'</newAxiom>
<newAxiom>'negative regulation of DNA metabolic process' SubClassOf 'negative regulation of macromolecule metabolic process'</newAxiom>
<newAxiom>'negative regulation of DNA metabolic process' SubClassOf 'negative regulation of nucleobase-containing compound metabolic process'</newAxiom>
<newAxiom>'negative regulation of DNA metabolic process' SubClassOf 'negatively regulates' some 'DNA metabolic process'</newAxiom>
<newAxiom>'negative regulation of DNA metabolic process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'DNA metabolic process')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051052</classIRI>
<classLabel>regulation of DNA metabolic process</classLabel>
<newAxiom>'regulation of DNA metabolic process' SubClassOf 'regulates' some 'DNA metabolic process'</newAxiom>
<newAxiom>'regulation of DNA metabolic process' SubClassOf 'regulation of nucleobase-containing compound metabolic process'</newAxiom>
<newAxiom>'regulation of DNA metabolic process' SubClassOf 'regulation of macromolecule metabolic process'</newAxiom>
<newAxiom>'regulation of DNA metabolic process' EquivalentTo 'biological regulation' and ('regulates' some 'DNA metabolic process')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051027</classIRI>
<classLabel>DNA transport</classLabel>
<newAxiom>'DNA transport' EquivalentTo 'transport' and ('has primary input' some 'deoxyribonucleic acid')</newAxiom>
<newAxiom>'DNA transport' SubClassOf 'has primary input' some 'deoxyribonucleic acid'</newAxiom>
<newAxiom>'DNA transport' SubClassOf 'nucleic acid transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046416</classIRI>
<classLabel>D-amino acid metabolic process</classLabel>
<newAxiom>'D-amino acid metabolic process' SubClassOf 'organic substance metabolic process'</newAxiom>
<newAxiom>'D-amino acid metabolic process' SubClassOf 'has primary input or output' some 'D-alpha-amino acid zwitterion'</newAxiom>
<newAxiom>'D-amino acid metabolic process' EquivalentTo 'metabolic process' and ('has primary input or output' some 'D-alpha-amino acid zwitterion')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046437</classIRI>
<classLabel>D-amino acid biosynthetic process</classLabel>
<newAxiom>'D-amino acid biosynthetic process' SubClassOf 'D-amino acid metabolic process'</newAxiom>
<newAxiom>'D-amino acid biosynthetic process' EquivalentTo 'biosynthetic process' and ('has primary output' some 'D-alpha-amino acid zwitterion')</newAxiom>
<newAxiom>'D-amino acid biosynthetic process' SubClassOf 'organic substance biosynthetic process'</newAxiom>
<newAxiom>'D-amino acid biosynthetic process' SubClassOf 'has primary output' some 'D-alpha-amino acid zwitterion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903624</classIRI>
<classLabel>regulation of DNA catabolic process</classLabel>
<newAxiom>'regulation of DNA catabolic process' SubClassOf 'regulation of cellular catabolic process'</newAxiom>
<newAxiom>'regulation of DNA catabolic process' SubClassOf 'regulation of DNA metabolic process'</newAxiom>
<newAxiom>'regulation of DNA catabolic process' EquivalentTo 'biological regulation' and ('regulates' some 'DNA catabolic process')</newAxiom>
<newAxiom>'regulation of DNA catabolic process' SubClassOf 'regulates' some 'DNA catabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903626</classIRI>
<classLabel>positive regulation of DNA catabolic process</classLabel>
<newAxiom>'positive regulation of DNA catabolic process' SubClassOf 'positively regulates' some 'DNA catabolic process'</newAxiom>
<newAxiom>'positive regulation of DNA catabolic process' SubClassOf 'positive regulation of cellular catabolic process'</newAxiom>
<newAxiom>'positive regulation of DNA catabolic process' EquivalentTo 'biological regulation' and ('positively regulates' some 'DNA catabolic process')</newAxiom>
<newAxiom>'positive regulation of DNA catabolic process' SubClassOf 'regulation of DNA catabolic process'</newAxiom>
<newAxiom>'positive regulation of DNA catabolic process' SubClassOf 'positive regulation of DNA metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903625</classIRI>
<classLabel>negative regulation of DNA catabolic process</classLabel>
<newAxiom>'negative regulation of DNA catabolic process' SubClassOf 'negative regulation of DNA metabolic process'</newAxiom>
<newAxiom>'negative regulation of DNA catabolic process' SubClassOf 'negative regulation of cellular catabolic process'</newAxiom>
<newAxiom>'negative regulation of DNA catabolic process' SubClassOf 'regulation of DNA catabolic process'</newAxiom>
<newAxiom>'negative regulation of DNA catabolic process' SubClassOf 'negatively regulates' some 'DNA catabolic process'</newAxiom>
<newAxiom>'negative regulation of DNA catabolic process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'DNA catabolic process')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003358</classIRI>
<classLabel>noradrenergic neuron development</classLabel>
<newAxiom>'noradrenergic neuron development' SubClassOf 'neuron development'</newAxiom>
<newAxiom>'noradrenergic neuron development' EquivalentTo 'developmental process' and ('results in development of' some 'noradrenergic neuron')</newAxiom>
<newAxiom>'noradrenergic neuron development' SubClassOf 'results in development of' some 'noradrenergic neuron'</newAxiom>
<newAxiom>'noradrenergic neuron development' SubClassOf 'part of' some 'noradrenergic neuron differentiation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003357</classIRI>
<classLabel>noradrenergic neuron differentiation</classLabel>
<newAxiom>'noradrenergic neuron differentiation' SubClassOf 'neuron differentiation'</newAxiom>
<newAxiom>'noradrenergic neuron differentiation' SubClassOf 'results in acquisition of features of' some 'noradrenergic neuron'</newAxiom>
<newAxiom>'noradrenergic neuron differentiation' EquivalentTo 'cell differentiation' and ('results in acquisition of features of' some 'noradrenergic neuron')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010324</classIRI>
<classLabel>membrane invagination</classLabel>
<newAxiom>'membrane invagination' SubClassOf 'membrane organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033054</classIRI>
<classLabel>D-glutamate metabolic process</classLabel>
<newAxiom>'D-glutamate metabolic process' SubClassOf 'glutamate metabolic process'</newAxiom>
<newAxiom>'D-glutamate metabolic process' SubClassOf 'has primary input or output' some 'D-glutamate(1-)'</newAxiom>
<newAxiom>'D-glutamate metabolic process' EquivalentTo 'metabolic process' and ('has primary input or output' some 'D-glutamate(1-)')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004518</classIRI>
<classLabel>nuclease activity</classLabel>
<newAxiom>'nuclease activity' SubClassOf 'hydrolase activity, acting on ester bonds'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004536</classIRI>
<classLabel>DNA nuclease activity</classLabel>
<newAxiom>'DNA nuclease activity' SubClassOf 'catalytic activity, acting on DNA'</newAxiom>
<newAxiom>'DNA nuclease activity' SubClassOf 'part of' some 'DNA metabolic process'</newAxiom>
<newAxiom>'DNA nuclease activity' SubClassOf 'nuclease activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015172</classIRI>
<classLabel>acidic amino acid transmembrane transporter activity</classLabel>
<newAxiom>'acidic amino acid transmembrane transporter activity' SubClassOf 'amino acid transmembrane transporter activity'</newAxiom>
<newAxiom>'acidic amino acid transmembrane transporter activity' SubClassOf 'part of' some 'acidic amino acid transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902511</classIRI>
<classLabel>negative regulation of apoptotic DNA fragmentation</classLabel>
<newAxiom>'negative regulation of apoptotic DNA fragmentation' SubClassOf 'negative regulation of DNA catabolic process'</newAxiom>
<newAxiom>'negative regulation of apoptotic DNA fragmentation' SubClassOf 'regulation of apoptotic DNA fragmentation'</newAxiom>
<newAxiom>'negative regulation of apoptotic DNA fragmentation' EquivalentTo 'biological regulation' and ('negatively regulates' some 'apoptotic DNA fragmentation')</newAxiom>
<newAxiom>'negative regulation of apoptotic DNA fragmentation' SubClassOf 'negatively regulates' some 'apoptotic DNA fragmentation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902510</classIRI>
<classLabel>regulation of apoptotic DNA fragmentation</classLabel>
<newAxiom>'regulation of apoptotic DNA fragmentation' SubClassOf 'regulation of DNA catabolic process'</newAxiom>
<newAxiom>'regulation of apoptotic DNA fragmentation' EquivalentTo 'biological regulation' and ('regulates' some 'apoptotic DNA fragmentation')</newAxiom>
<newAxiom>'regulation of apoptotic DNA fragmentation' SubClassOf 'regulates' some 'apoptotic DNA fragmentation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902512</classIRI>
<classLabel>positive regulation of apoptotic DNA fragmentation</classLabel>
<newAxiom>'positive regulation of apoptotic DNA fragmentation' SubClassOf 'positively regulates' some 'apoptotic DNA fragmentation'</newAxiom>
<newAxiom>'positive regulation of apoptotic DNA fragmentation' SubClassOf 'positive regulation of DNA catabolic process'</newAxiom>
<newAxiom>'positive regulation of apoptotic DNA fragmentation' EquivalentTo 'biological regulation' and ('positively regulates' some 'apoptotic DNA fragmentation')</newAxiom>
<newAxiom>'positive regulation of apoptotic DNA fragmentation' SubClassOf 'regulation of apoptotic DNA fragmentation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_29989</classIRI>
<classLabel>D-glutamate(2-)</classLabel>
<newAxiom>'D-glutamate(2-)' SubClassOf http://purl.obolibrary.org/obo/chebi#is_enantiomer_of some 'L-glutamate(2-)'</newAxiom>
<newAxiom>'D-glutamate(2-)' SubClassOf 'glutamate(2-)'</newAxiom>
<newAxiom>'D-glutamate(2-)' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of some 'D-glutamate(1-)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_29985</classIRI>
<classLabel>L-glutamate(1-)</classLabel>
<newAxiom>'L-glutamate(1-)' SubClassOf http://purl.obolibrary.org/obo/chebi#is_enantiomer_of some 'D-glutamate(1-)'</newAxiom>
<newAxiom>'L-glutamate(1-)' SubClassOf 'has role' some 'EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor'</newAxiom>
<newAxiom>'L-glutamate(1-)' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of some 'L-glutamate(2-)'</newAxiom>
<newAxiom>'L-glutamate(1-)' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of some 'L-glutamic acid'</newAxiom>
<newAxiom>'L-glutamate(1-)' SubClassOf 'has role' some 'Saccharomyces cerevisiae metabolite'</newAxiom>
<newAxiom>'L-glutamate(1-)' SubClassOf 'glutamate(1-)'</newAxiom>
<newAxiom>'L-glutamate(1-)' SubClassOf 'has role' some 'human metabolite'</newAxiom>
<newAxiom>'L-glutamate(1-)' SubClassOf 'polar amino acid zwitterion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_29986</classIRI>
<classLabel>D-glutamate(1-)</classLabel>
<newAxiom>'D-glutamate(1-)' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of some 'D-glutamate(2-)'</newAxiom>
<newAxiom>'D-glutamate(1-)' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of some 'D-glutamic acid'</newAxiom>
<newAxiom>'D-glutamate(1-)' SubClassOf 'glutamate(1-)'</newAxiom>
<newAxiom>'D-glutamate(1-)' SubClassOf http://purl.obolibrary.org/obo/chebi#is_enantiomer_of some 'L-glutamate(1-)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_29988</classIRI>
<classLabel>L-glutamate(2-)</classLabel>
<newAxiom>'L-glutamate(2-)' SubClassOf 'glutamate(2-)'</newAxiom>
<newAxiom>'L-glutamate(2-)' SubClassOf 'L-alpha-amino acid anion'</newAxiom>
<newAxiom>'L-glutamate(2-)' SubClassOf http://purl.obolibrary.org/obo/chebi#is_enantiomer_of some 'D-glutamate(2-)'</newAxiom>
<newAxiom>'L-glutamate(2-)' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of some 'L-glutamate(1-)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_59871</classIRI>
<classLabel>D-alpha-amino acid zwitterion</classLabel>
<newAxiom>'D-alpha-amino acid zwitterion' SubClassOf 'amino acid zwitterion'</newAxiom>
<newAxiom>'D-alpha-amino acid zwitterion' SubClassOf http://purl.obolibrary.org/obo/chebi#is_tautomer_of some 'D-alpha-amino acid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006900</classIRI>
<classLabel>vesicle budding from membrane</classLabel>
<newAxiom>'vesicle budding from membrane' SubClassOf 'membrane organization'</newAxiom>
<newAxiom>'vesicle budding from membrane' SubClassOf 'part of' some 'vesicle-mediated transport'</newAxiom>
<newAxiom>'vesicle budding from membrane' SubClassOf 'vesicle organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006897</classIRI>
<classLabel>endocytosis</classLabel>
<newAxiom>'endocytosis' SubClassOf 'has target end location' some 'cytoplasmic vesicle'</newAxiom>
<newAxiom>'endocytosis' SubClassOf 'import into cell'</newAxiom>
<newAxiom>'endocytosis' SubClassOf 'has_part' some 'vesicle budding from membrane'</newAxiom>
<newAxiom>'endocytosis' SubClassOf 'has_part' some 'membrane invagination'</newAxiom>
<newAxiom>'endocytosis' SubClassOf 'vesicle-mediated transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_16015</classIRI>
<classLabel>L-glutamic acid</classLabel>
<newAxiom>'L-glutamic acid' SubClassOf 'has role' some 'Escherichia coli metabolite'</newAxiom>
<newAxiom>'L-glutamic acid' SubClassOf 'glutamic acid'</newAxiom>
<newAxiom>'L-glutamic acid' SubClassOf 'glutamine family amino acid'</newAxiom>
<newAxiom>'L-glutamic acid' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of some 'L-glutamate(1-)'</newAxiom>
<newAxiom>'L-glutamic acid' SubClassOf 'has role' some 'micronutrient'</newAxiom>
<newAxiom>'L-glutamic acid' SubClassOf http://purl.obolibrary.org/obo/chebi#is_enantiomer_of some 'D-glutamic acid'</newAxiom>
<newAxiom>'L-glutamic acid' SubClassOf 'has role' some 'ferroptosis inducer'</newAxiom>
<newAxiom>'L-glutamic acid' SubClassOf 'has role' some 'nutraceutical'</newAxiom>
<newAxiom>'L-glutamic acid' SubClassOf 'has role' some 'neurotransmitter'</newAxiom>
<newAxiom>'L-glutamic acid' SubClassOf 'has role' some 'mouse metabolite'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000752</classIRI>
<classLabel>cone retinal bipolar cell</classLabel>
<newAxiom>'cone retinal bipolar cell' SubClassOf 'synapsed by' some 'retinal cone cell'</newAxiom>
<newAxiom>'cone retinal bipolar cell' SubClassOf 'retinal bipolar neuron'</newAxiom>
<newAxiom>'cone retinal bipolar cell' EquivalentTo 'retinal bipolar neuron' and ('synapsed by' some 'retinal cone cell')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_50733</classIRI>
<classLabel>nutraceutical</classLabel>
<newAxiom>'nutraceutical' SubClassOf 'drug'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000278</classIRI>
<classLabel>regulation of DNA biosynthetic process</classLabel>
<newAxiom>'regulation of DNA biosynthetic process' SubClassOf 'regulates' some 'DNA biosynthetic process'</newAxiom>
<newAxiom>'regulation of DNA biosynthetic process' SubClassOf 'regulation of cellular biosynthetic process'</newAxiom>
<newAxiom>'regulation of DNA biosynthetic process' SubClassOf 'regulation of DNA metabolic process'</newAxiom>
<newAxiom>'regulation of DNA biosynthetic process' SubClassOf 'regulation of macromolecule biosynthetic process'</newAxiom>
<newAxiom>'regulation of DNA biosynthetic process' EquivalentTo 'biological regulation' and ('regulates' some 'DNA biosynthetic process')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000279</classIRI>
<classLabel>negative regulation of DNA biosynthetic process</classLabel>
<newAxiom>'negative regulation of DNA biosynthetic process' SubClassOf 'negative regulation of DNA metabolic process'</newAxiom>
<newAxiom>'negative regulation of DNA biosynthetic process' SubClassOf 'negative regulation of macromolecule biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of DNA biosynthetic process' SubClassOf 'regulation of DNA biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of DNA biosynthetic process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'DNA biosynthetic process')</newAxiom>
<newAxiom>'negative regulation of DNA biosynthetic process' SubClassOf 'negatively regulates' some 'DNA biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of DNA biosynthetic process' SubClassOf 'negative regulation of cellular biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000850</classIRI>
<classLabel>serotonergic neuron</classLabel>
<newAxiom>'serotonergic neuron' SubClassOf 'capable of' some 'serotonin secretion, neurotransmission'</newAxiom>
<newAxiom>'serotonergic neuron' SubClassOf 'serotonin secreting cell'</newAxiom>
<newAxiom>'serotonergic neuron' EquivalentTo 'neuron' and ('capable of' some 'serotonin secretion, neurotransmission')</newAxiom>
<newAxiom>'serotonergic neuron' SubClassOf 'neuron'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061533</classIRI>
<classLabel>norepinephrine secretion, neurotransmission</classLabel>
<newAxiom>'norepinephrine secretion, neurotransmission' SubClassOf 'catecholamine secretion, neurotransmission'</newAxiom>
<newAxiom>'norepinephrine secretion, neurotransmission' EquivalentTo 'neurotransmitter secretion' and ('has primary input' some '(R)-noradrenaline(1+)')</newAxiom>
<newAxiom>'norepinephrine secretion, neurotransmission' SubClassOf 'norepinephrine secretion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005313</classIRI>
<classLabel>L-glutamate transmembrane transporter activity</classLabel>
<newAxiom>'L-glutamate transmembrane transporter activity' SubClassOf 'carboxylic acid transmembrane transporter activity'</newAxiom>
<newAxiom>'L-glutamate transmembrane transporter activity' SubClassOf 'has primary input' some 'L-glutamate(1-)'</newAxiom>
<newAxiom>'L-glutamate transmembrane transporter activity' SubClassOf 'acidic amino acid transmembrane transporter activity'</newAxiom>
<newAxiom>'L-glutamate transmembrane transporter activity' SubClassOf 'part of' some 'L-glutamate transmembrane transport'</newAxiom>
<newAxiom>'L-glutamate transmembrane transporter activity' EquivalentTo 'transmembrane transporter activity' and ('has primary input' some 'L-glutamate(1-)')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032986</classIRI>
<classLabel>protein-DNA complex disassembly</classLabel>
<newAxiom>'protein-DNA complex disassembly' SubClassOf 'protein-DNA complex organization'</newAxiom>
<newAxiom>'protein-DNA complex disassembly' SubClassOf 'protein-containing complex disassembly'</newAxiom>
<newAxiom>'protein-DNA complex disassembly' SubClassOf 'results in disassembly of' some 'protein-DNA complex'</newAxiom>
<newAxiom>'protein-DNA complex disassembly' EquivalentTo 'cellular component disassembly' and ('results in disassembly of' some 'protein-DNA complex')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032993</classIRI>
<classLabel>protein-DNA complex</classLabel>
<newAxiom>'protein-DNA complex' SubClassOf 'has_part' some 'deoxyribonucleic acid'</newAxiom>
<newAxiom>'protein-DNA complex' SubClassOf 'protein-containing complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0065004</classIRI>
<classLabel>protein-DNA complex assembly</classLabel>
<newAxiom>'protein-DNA complex assembly' SubClassOf 'protein-DNA complex organization'</newAxiom>
<newAxiom>'protein-DNA complex assembly' SubClassOf 'protein-containing complex assembly'</newAxiom>
<newAxiom>'protein-DNA complex assembly' SubClassOf 'results in assembly of' some 'protein-DNA complex'</newAxiom>
<newAxiom>'protein-DNA complex assembly' EquivalentTo 'cellular component assembly' and ('results in assembly of' some 'protein-DNA complex')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905155</classIRI>
<classLabel>positive regulation of membrane invagination</classLabel>
<newAxiom>'positive regulation of membrane invagination' SubClassOf 'positive regulation of cellular component organization'</newAxiom>
<newAxiom>'positive regulation of membrane invagination' SubClassOf 'regulation of membrane invagination'</newAxiom>
<newAxiom>'positive regulation of membrane invagination' EquivalentTo 'biological regulation' and ('positively regulates' some 'membrane invagination')</newAxiom>
<newAxiom>'positive regulation of membrane invagination' SubClassOf 'positively regulates' some 'membrane invagination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905153</classIRI>
<classLabel>regulation of membrane invagination</classLabel>
<newAxiom>'regulation of membrane invagination' EquivalentTo 'biological regulation' and ('regulates' some 'membrane invagination')</newAxiom>
<newAxiom>'regulation of membrane invagination' SubClassOf 'regulation of cellular component organization'</newAxiom>
<newAxiom>'regulation of membrane invagination' SubClassOf 'regulates' some 'membrane invagination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905154</classIRI>
<classLabel>negative regulation of membrane invagination</classLabel>
<newAxiom>'negative regulation of membrane invagination' EquivalentTo 'biological regulation' and ('negatively regulates' some 'membrane invagination')</newAxiom>
<newAxiom>'negative regulation of membrane invagination' SubClassOf 'negatively regulates' some 'membrane invagination'</newAxiom>
<newAxiom>'negative regulation of membrane invagination' SubClassOf 'regulation of membrane invagination'</newAxiom>
<newAxiom>'negative regulation of membrane invagination' SubClassOf 'negative regulation of cellular component organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0008025</classIRI>
<classLabel>noradrenergic neuron</classLabel>
<newAxiom>'noradrenergic neuron' SubClassOf 'capable of' some 'norepinephrine secretion, neurotransmission'</newAxiom>
<newAxiom>'noradrenergic neuron' EquivalentTo 'neuron' and ('capable of' some 'norepinephrine secretion, neurotransmission')</newAxiom>
<newAxiom>'noradrenergic neuron' SubClassOf 'noradrenergic cell'</newAxiom>
<newAxiom>'noradrenergic neuron' SubClassOf 'neuron'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060096</classIRI>
<classLabel>serotonin secretion, neurotransmission</classLabel>
<newAxiom>'serotonin secretion, neurotransmission' EquivalentTo 'neurotransmitter secretion' and ('has primary input' some 'serotonin(1+)')</newAxiom>
<newAxiom>'serotonin secretion, neurotransmission' SubClassOf 'serotonin secretion'</newAxiom>
<newAxiom>'serotonin secretion, neurotransmission' SubClassOf 'neurotransmitter secretion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051938</classIRI>
<classLabel>L-glutamate import</classLabel>
<newAxiom>'L-glutamate import' SubClassOf 'acidic amino acid transport'</newAxiom>
<newAxiom>'L-glutamate import' EquivalentTo 'transport' and ('has primary input' some 'L-glutamate(1-)')</newAxiom>
<newAxiom>'L-glutamate import' SubClassOf 'has primary input' some 'L-glutamate(1-)'</newAxiom>
<newAxiom>'L-glutamate import' SubClassOf 'carboxylic acid transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030100</classIRI>
<classLabel>regulation of endocytosis</classLabel>
<newAxiom>'regulation of endocytosis' SubClassOf 'regulation of cellular component organization'</newAxiom>
<newAxiom>'regulation of endocytosis' SubClassOf 'regulation of vesicle-mediated transport'</newAxiom>
<newAxiom>'regulation of endocytosis' SubClassOf 'regulates' some 'endocytosis'</newAxiom>
<newAxiom>'regulation of endocytosis' EquivalentTo 'biological regulation' and ('regulates' some 'endocytosis')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905232</classIRI>
<classLabel>cellular response to L-glutamate</classLabel>
<newAxiom>'cellular response to L-glutamate' SubClassOf 'response to L-glutamate'</newAxiom>
<newAxiom>'cellular response to L-glutamate' EquivalentTo 'cellular response to chemical stimulus' and ('has input' some 'L-glutamate(1-)')</newAxiom>
<newAxiom>'cellular response to L-glutamate' SubClassOf 'cellular response to organonitrogen compound'</newAxiom>
<newAxiom>'cellular response to L-glutamate' SubClassOf 'cellular response to oxygen-containing compound'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006308</classIRI>
<classLabel>DNA catabolic process</classLabel>
<newAxiom>'DNA catabolic process' SubClassOf 'macromolecule catabolic process'</newAxiom>
<newAxiom>'DNA catabolic process' SubClassOf 'has primary input' some 'deoxyribonucleic acid'</newAxiom>
<newAxiom>'DNA catabolic process' EquivalentTo 'catabolic process' and ('has primary input' some 'deoxyribonucleic acid')</newAxiom>
<newAxiom>'DNA catabolic process' SubClassOf 'DNA metabolic process'</newAxiom>
<newAxiom>'DNA catabolic process' SubClassOf 'nucleobase-containing compound catabolic process'</newAxiom>
<newAxiom>'DNA catabolic process' SubClassOf 'has_part' some 'DNA nuclease activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006309</classIRI>
<classLabel>apoptotic DNA fragmentation</classLabel>
<newAxiom>'apoptotic DNA fragmentation' SubClassOf 'DNA catabolic process'</newAxiom>
<newAxiom>'apoptotic DNA fragmentation' SubClassOf 'part of' some 'apoptotic nuclear changes'</newAxiom>
<newAxiom>'apoptotic DNA fragmentation' EquivalentTo 'DNA catabolic process' and ('part of' some 'apoptotic nuclear changes')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_75600</classIRI>
<classLabel>EC 6.3.* (C-N bond-forming ligase) inhibitor</classLabel>
<newAxiom>'EC 6.3.* (C-N bond-forming ligase) inhibitor' SubClassOf 'EC 6.* (ligase) inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_75603</classIRI>
<classLabel>EC 6.* (ligase) inhibitor</classLabel>
<newAxiom>'EC 6.* (ligase) inhibitor' SubClassOf 'enzyme inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048194</classIRI>
<classLabel>Golgi vesicle budding</classLabel>
<newAxiom>'Golgi vesicle budding' SubClassOf 'part of' some 'Golgi vesicle transport'</newAxiom>
<newAxiom>'Golgi vesicle budding' SubClassOf 'occurs in' some 'Golgi membrane'</newAxiom>
<newAxiom>'Golgi vesicle budding' SubClassOf 'has output' some 'Golgi-associated vesicle'</newAxiom>
<newAxiom>'Golgi vesicle budding' EquivalentTo 'vesicle budding from membrane' and ('occurs in' some 'Golgi membrane') and ('has output' some 'Golgi-associated vesicle')</newAxiom>
<newAxiom>'Golgi vesicle budding' SubClassOf 'vesicle budding from membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_50298</classIRI>
<classLabel>canonical deoxyribonucleotide residue</classLabel>
<newAxiom>'canonical deoxyribonucleotide residue' SubClassOf 'canonical nucleotide residue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_15966</classIRI>
<classLabel>D-glutamic acid</classLabel>
<newAxiom>'D-glutamic acid' SubClassOf 'has role' some 'mouse metabolite'</newAxiom>
<newAxiom>'D-glutamic acid' SubClassOf 'has role' some 'Escherichia coli metabolite'</newAxiom>
<newAxiom>'D-glutamic acid' SubClassOf 'D-alpha-amino acid'</newAxiom>
<newAxiom>'D-glutamic acid' SubClassOf 'glutamic acid'</newAxiom>
<newAxiom>'D-glutamic acid' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of some 'D-glutamate(1-)'</newAxiom>
<newAxiom>'D-glutamic acid' SubClassOf http://purl.obolibrary.org/obo/chebi#is_enantiomer_of some 'L-glutamic acid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045807</classIRI>
<classLabel>positive regulation of endocytosis</classLabel>
<newAxiom>'positive regulation of endocytosis' EquivalentTo 'biological regulation' and ('positively regulates' some 'endocytosis')</newAxiom>
<newAxiom>'positive regulation of endocytosis' SubClassOf 'positive regulation of transport'</newAxiom>
<newAxiom>'positive regulation of endocytosis' SubClassOf 'positively regulates' some 'endocytosis'</newAxiom>
<newAxiom>'positive regulation of endocytosis' SubClassOf 'regulation of endocytosis'</newAxiom>
<newAxiom>'positive regulation of endocytosis' SubClassOf 'positive regulation of cellular component organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000573</classIRI>
<classLabel>positive regulation of DNA biosynthetic process</classLabel>
<newAxiom>'positive regulation of DNA biosynthetic process' SubClassOf 'positively regulates' some 'DNA biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of DNA biosynthetic process' SubClassOf 'positive regulation of DNA metabolic process'</newAxiom>
<newAxiom>'positive regulation of DNA biosynthetic process' SubClassOf 'regulation of DNA biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of DNA biosynthetic process' EquivalentTo 'biological regulation' and ('positively regulates' some 'DNA biosynthetic process')</newAxiom>
<newAxiom>'positive regulation of DNA biosynthetic process' SubClassOf 'positive regulation of macromolecule biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of DNA biosynthetic process' SubClassOf 'positive regulation of cellular biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045806</classIRI>
<classLabel>negative regulation of endocytosis</classLabel>
<newAxiom>'negative regulation of endocytosis' SubClassOf 'regulation of endocytosis'</newAxiom>
<newAxiom>'negative regulation of endocytosis' SubClassOf 'negatively regulates' some 'endocytosis'</newAxiom>
<newAxiom>'negative regulation of endocytosis' EquivalentTo 'biological regulation' and ('negatively regulates' some 'endocytosis')</newAxiom>
<newAxiom>'negative regulation of endocytosis' SubClassOf 'negative regulation of transport'</newAxiom>
<newAxiom>'negative regulation of endocytosis' SubClassOf 'negative regulation of cellular component organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_76823</classIRI>
<classLabel>EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor</classLabel>
<newAxiom>'EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor' SubClassOf 'EC 6.3.* (C-N bond-forming ligase) inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_33793</classIRI>
<classLabel>canonical deoxyribonucleoside residue</classLabel>
<newAxiom>'canonical deoxyribonucleoside residue' SubClassOf 'canonical nucleoside residue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097054</classIRI>
<classLabel>L-glutamate biosynthetic process</classLabel>
<newAxiom>'L-glutamate biosynthetic process' SubClassOf 'has primary input or output' some 'L-glutamate(1-)'</newAxiom>
<newAxiom>'L-glutamate biosynthetic process' EquivalentTo 'metabolic process' and ('has primary input or output' some 'L-glutamate(1-)')</newAxiom>
<newAxiom>'L-glutamate biosynthetic process' SubClassOf 'glutamate biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006259</classIRI>
<classLabel>DNA metabolic process</classLabel>
<newAxiom>'DNA metabolic process' EquivalentTo 'metabolic process' and ('has primary input or output' some 'deoxyribonucleic acid')</newAxiom>
<newAxiom>'DNA metabolic process' SubClassOf 'nucleic acid metabolic process'</newAxiom>
<newAxiom>'DNA metabolic process' SubClassOf 'has primary input or output' some 'deoxyribonucleic acid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_24319</classIRI>
<classLabel>EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor</classLabel>
<newAxiom>'EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor' SubClassOf 'EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140239</classIRI>
<classLabel>postsynaptic endocytosis</classLabel>
<newAxiom>'postsynaptic endocytosis' SubClassOf 'endocytosis'</newAxiom>
<newAxiom>'postsynaptic endocytosis' SubClassOf 'vesicle-mediated transport in synapse'</newAxiom>
<newAxiom>'postsynaptic endocytosis' SubClassOf 'establishment of localization in cell'</newAxiom>
<newAxiom>'postsynaptic endocytosis' SubClassOf 'occurs in' some 'postsynapse'</newAxiom>
<newAxiom>'postsynaptic endocytosis' EquivalentTo 'endocytosis' and ('occurs in' some 'postsynapse')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140238</classIRI>
<classLabel>presynaptic endocytosis</classLabel>
<newAxiom>'presynaptic endocytosis' SubClassOf 'endocytosis'</newAxiom>
<newAxiom>'presynaptic endocytosis' SubClassOf 'establishment of localization in cell'</newAxiom>
<newAxiom>'presynaptic endocytosis' SubClassOf 'vesicle-mediated transport in synapse'</newAxiom>
<newAxiom>'presynaptic endocytosis' SubClassOf 'occurs in' some 'presynapse'</newAxiom>
<newAxiom>'presynaptic endocytosis' EquivalentTo 'endocytosis' and ('occurs in' some 'presynapse')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019478</classIRI>
<classLabel>D-amino acid catabolic process</classLabel>
<newAxiom>'D-amino acid catabolic process' SubClassOf 'organic substance catabolic process'</newAxiom>
<newAxiom>'D-amino acid catabolic process' EquivalentTo 'catabolic process' and ('has primary input' some 'D-alpha-amino acid zwitterion')</newAxiom>
<newAxiom>'D-amino acid catabolic process' SubClassOf 'D-amino acid metabolic process'</newAxiom>
<newAxiom>'D-amino acid catabolic process' SubClassOf 'has primary input' some 'D-alpha-amino acid zwitterion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_8600006</classIRI>
<classLabel>visceral striated muscle tissue</classLabel>
<newAxiom>'visceral striated muscle tissue' SubClassOf 'visceral muscle tissue'</newAxiom>
<newAxiom>'visceral striated muscle tissue' SubClassOf 'striated muscle tissue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_8600004</classIRI>
<classLabel>visceral muscle tissue</classLabel>
<newAxiom>'visceral muscle tissue' SubClassOf 'composed primarily of' some 'visceral muscle cell'</newAxiom>
<newAxiom>'visceral muscle tissue' SubClassOf 'muscle tissue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015813</classIRI>
<classLabel>L-glutamate transmembrane transport</classLabel>
<newAxiom>'L-glutamate transmembrane transport' SubClassOf 'carboxylic acid transmembrane transport'</newAxiom>
<newAxiom>'L-glutamate transmembrane transport' SubClassOf 'amino acid transmembrane transport'</newAxiom>
<newAxiom>'L-glutamate transmembrane transport' EquivalentTo 'acidic amino acid transport' and ('results in transport across' some 'membrane') and ('has primary input' some 'L-glutamate(1-)')</newAxiom>
<newAxiom>'L-glutamate transmembrane transport' SubClassOf 'L-glutamate import'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015869</classIRI>
<classLabel>protein-DNA complex transport</classLabel>
<newAxiom>'protein-DNA complex transport' SubClassOf 'nucleobase-containing compound transport'</newAxiom>
<newAxiom>'protein-DNA complex transport' SubClassOf 'protein-containing complex localization'</newAxiom>
<newAxiom>'protein-DNA complex transport' SubClassOf 'intracellular protein transport'</newAxiom>
<newAxiom>'protein-DNA complex transport' SubClassOf 'has primary input' some 'protein-DNA complex'</newAxiom>
<newAxiom>'protein-DNA complex transport' EquivalentTo 'transport' and ('has primary input' some 'protein-DNA complex')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904390</classIRI>
<classLabel>cone retinal bipolar cell differentiation</classLabel>
<newAxiom>'cone retinal bipolar cell differentiation' EquivalentTo 'cell differentiation' and ('results in acquisition of features of' some 'cone retinal bipolar cell')</newAxiom>
<newAxiom>'cone retinal bipolar cell differentiation' SubClassOf 'retinal bipolar neuron differentiation'</newAxiom>
<newAxiom>'cone retinal bipolar cell differentiation' SubClassOf 'results in acquisition of features of' some 'cone retinal bipolar cell'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046872</classIRI>
<classLabel>metal ion binding</classLabel>
<newAxiom>'metal ion binding' SubClassOf 'cation binding'</newAxiom>
<newAxiom>'metal ion binding' SubClassOf 'has input' some 'metal cation'</newAxiom>
<newAxiom>'metal ion binding' EquivalentTo 'binding' and ('has input' some 'metal cation')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044247</classIRI>
<classLabel>cellular polysaccharide catabolic process</classLabel>
<newAxiom>'cellular polysaccharide catabolic process' SubClassOf 'cellular carbohydrate catabolic process'</newAxiom>
<newAxiom>'cellular polysaccharide catabolic process' SubClassOf 'polysaccharide catabolic process'</newAxiom>
<newAxiom>'cellular polysaccharide catabolic process' SubClassOf 'cellular polysaccharide metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044262</classIRI>
<classLabel>cellular carbohydrate metabolic process</classLabel>
<newAxiom>'cellular carbohydrate metabolic process' SubClassOf 'cellular metabolic process'</newAxiom>
<newAxiom>'cellular carbohydrate metabolic process' SubClassOf 'carbohydrate metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044264</classIRI>
<classLabel>cellular polysaccharide metabolic process</classLabel>
<newAxiom>'cellular polysaccharide metabolic process' SubClassOf 'cellular macromolecule metabolic process'</newAxiom>
<newAxiom>'cellular polysaccharide metabolic process' SubClassOf 'cellular carbohydrate metabolic process'</newAxiom>
<newAxiom>'cellular polysaccharide metabolic process' SubClassOf 'polysaccharide metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044265</classIRI>
<classLabel>cellular macromolecule catabolic process</classLabel>
<newAxiom>'cellular macromolecule catabolic process' SubClassOf 'cellular catabolic process'</newAxiom>
<newAxiom>'cellular macromolecule catabolic process' SubClassOf 'cellular macromolecule metabolic process'</newAxiom>
<newAxiom>'cellular macromolecule catabolic process' SubClassOf 'macromolecule catabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044260</classIRI>
<classLabel>cellular macromolecule metabolic process</classLabel>
<newAxiom>'cellular macromolecule metabolic process' SubClassOf 'macromolecule metabolic process'</newAxiom>
<newAxiom>'cellular macromolecule metabolic process' SubClassOf 'cellular metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071890</classIRI>
<classLabel>bicarbonate binding</classLabel>
<newAxiom>'bicarbonate binding' SubClassOf 'has input' some 'hydrogencarbonate'</newAxiom>
<newAxiom>'bicarbonate binding' SubClassOf 'anion binding'</newAxiom>
<newAxiom>'bicarbonate binding' EquivalentTo 'binding' and ('has input' some 'hydrogencarbonate')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044275</classIRI>
<classLabel>cellular carbohydrate catabolic process</classLabel>
<newAxiom>'cellular carbohydrate catabolic process' SubClassOf 'cellular carbohydrate metabolic process'</newAxiom>
<newAxiom>'cellular carbohydrate catabolic process' SubClassOf 'carbohydrate catabolic process'</newAxiom>
<newAxiom>'cellular carbohydrate catabolic process' SubClassOf 'cellular catabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051378</classIRI>
<classLabel>serotonin binding</classLabel>
<newAxiom>'serotonin binding' SubClassOf 'has input' some 'serotonin(1+)'</newAxiom>
<newAxiom>'serotonin binding' EquivalentTo 'binding' and ('has input' some 'serotonin(1+)')</newAxiom>
<newAxiom>'serotonin binding' SubClassOf 'cation binding'</newAxiom>
<newAxiom>'serotonin binding' SubClassOf 'amine binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019207</classIRI>
<classLabel>kinase regulator activity</classLabel>
<newAxiom>'kinase regulator activity' EquivalentTo 'molecular function regulator activity' and ('directly regulates' some 'kinase activity')</newAxiom>
<newAxiom>'kinase regulator activity' SubClassOf 'directly regulates' some 'kinase activity'</newAxiom>
<newAxiom>'kinase regulator activity' SubClassOf 'enzyme regulator activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019209</classIRI>
<classLabel>kinase activator activity</classLabel>
<newAxiom>'kinase activator activity' SubClassOf 'directly positively regulates' some 'kinase activity'</newAxiom>
<newAxiom>'kinase activator activity' SubClassOf 'kinase regulator activity'</newAxiom>
<newAxiom>'kinase activator activity' SubClassOf 'enzyme activator activity'</newAxiom>
<newAxiom>'kinase activator activity' EquivalentTo 'molecular function regulator activity' and ('directly positively regulates' some 'kinase activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051380</classIRI>
<classLabel>norepinephrine binding</classLabel>
<newAxiom>'norepinephrine binding' SubClassOf 'has input' some '(R)-noradrenaline(1+)'</newAxiom>
<newAxiom>'norepinephrine binding' EquivalentTo 'binding' and ('has input' some '(R)-noradrenaline(1+)')</newAxiom>
<newAxiom>'norepinephrine binding' SubClassOf 'cation binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003723</classIRI>
<classLabel>RNA binding</classLabel>
<newAxiom>'RNA binding' SubClassOf 'nucleic acid binding'</newAxiom>
<newAxiom>'RNA binding' SubClassOf 'has input' some 'ribonucleic acid'</newAxiom>
<newAxiom>'RNA binding' EquivalentTo 'binding' and ('has input' some 'ribonucleic acid')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019210</classIRI>
<classLabel>kinase inhibitor activity</classLabel>
<newAxiom>'kinase inhibitor activity' SubClassOf 'kinase regulator activity'</newAxiom>
<newAxiom>'kinase inhibitor activity' SubClassOf 'enzyme inhibitor activity'</newAxiom>
<newAxiom>'kinase inhibitor activity' EquivalentTo 'molecular function regulator activity' and ('directly negatively regulates' some 'kinase activity')</newAxiom>
<newAxiom>'kinase inhibitor activity' SubClassOf 'directly negatively regulates' some 'kinase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046848</classIRI>
<classLabel>hydroxyapatite binding</classLabel>
<newAxiom>'hydroxyapatite binding' SubClassOf 'has input' some 'hydroxylapatite'</newAxiom>
<newAxiom>'hydroxyapatite binding' SubClassOf 'binding'</newAxiom>
<newAxiom>'hydroxyapatite binding' EquivalentTo 'binding' and ('has input' some 'hydroxylapatite')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070405</classIRI>
<classLabel>ammonium ion binding</classLabel>
<newAxiom>'ammonium ion binding' SubClassOf 'cation binding'</newAxiom>
<newAxiom>'ammonium ion binding' EquivalentTo 'binding' and ('has input' some 'ammonium')</newAxiom>
<newAxiom>'ammonium ion binding' SubClassOf 'has input' some 'ammonium'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015631</classIRI>
<classLabel>tubulin binding</classLabel>
<newAxiom>'tubulin binding' SubClassOf 'cytoskeletal protein binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904526</classIRI>
<classLabel>regulation of microtubule binding</classLabel>
<newAxiom>'regulation of microtubule binding' SubClassOf 'regulates' some 'microtubule binding'</newAxiom>
<newAxiom>'regulation of microtubule binding' SubClassOf 'regulation of protein binding'</newAxiom>
<newAxiom>'regulation of microtubule binding' EquivalentTo 'biological regulation' and ('regulates' some 'microtubule binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904527</classIRI>
<classLabel>negative regulation of microtubule binding</classLabel>
<newAxiom>'negative regulation of microtubule binding' EquivalentTo 'biological regulation' and ('negatively regulates' some 'microtubule binding')</newAxiom>
<newAxiom>'negative regulation of microtubule binding' SubClassOf 'negative regulation of protein binding'</newAxiom>
<newAxiom>'negative regulation of microtubule binding' SubClassOf 'regulation of microtubule binding'</newAxiom>
<newAxiom>'negative regulation of microtubule binding' SubClassOf 'negatively regulates' some 'microtubule binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904528</classIRI>
<classLabel>positive regulation of microtubule binding</classLabel>
<newAxiom>'positive regulation of microtubule binding' EquivalentTo 'biological regulation' and ('positively regulates' some 'microtubule binding')</newAxiom>
<newAxiom>'positive regulation of microtubule binding' SubClassOf 'positive regulation of protein binding'</newAxiom>
<newAxiom>'positive regulation of microtubule binding' SubClassOf 'positively regulates' some 'microtubule binding'</newAxiom>
<newAxiom>'positive regulation of microtubule binding' SubClassOf 'regulation of microtubule binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003682</classIRI>
<classLabel>chromatin binding</classLabel>
<newAxiom>'chromatin binding' EquivalentTo 'binding' and ('has input' some 'chromatin')</newAxiom>
<newAxiom>'chromatin binding' SubClassOf 'has input' some 'chromatin'</newAxiom>
<newAxiom>'chromatin binding' SubClassOf 'binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003676</classIRI>
<classLabel>nucleic acid binding</classLabel>
<newAxiom>'nucleic acid binding' EquivalentTo 'binding' and ('has input' some 'nucleic acid')</newAxiom>
<newAxiom>'nucleic acid binding' SubClassOf 'organic cyclic compound binding'</newAxiom>
<newAxiom>'nucleic acid binding' SubClassOf 'has input' some 'nucleic acid'</newAxiom>
<newAxiom>'nucleic acid binding' SubClassOf 'heterocyclic compound binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034645</classIRI>
<classLabel>cellular macromolecule biosynthetic process</classLabel>
<newAxiom>'cellular macromolecule biosynthetic process' SubClassOf 'macromolecule biosynthetic process'</newAxiom>
<newAxiom>'cellular macromolecule biosynthetic process' SubClassOf 'cellular biosynthetic process'</newAxiom>
<newAxiom>'cellular macromolecule biosynthetic process' SubClassOf 'cellular macromolecule metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033342</classIRI>
<classLabel>negative regulation of collagen binding</classLabel>
<newAxiom>'negative regulation of collagen binding' EquivalentTo 'biological regulation' and ('negatively regulates' some 'collagen binding')</newAxiom>
<newAxiom>'negative regulation of collagen binding' SubClassOf 'regulation of collagen binding'</newAxiom>
<newAxiom>'negative regulation of collagen binding' SubClassOf 'negatively regulates' some 'collagen binding'</newAxiom>
<newAxiom>'negative regulation of collagen binding' SubClassOf 'negative regulation of binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033341</classIRI>
<classLabel>regulation of collagen binding</classLabel>
<newAxiom>'regulation of collagen binding' SubClassOf 'regulation of binding'</newAxiom>
<newAxiom>'regulation of collagen binding' SubClassOf 'regulates' some 'collagen binding'</newAxiom>
<newAxiom>'regulation of collagen binding' EquivalentTo 'biological regulation' and ('regulates' some 'collagen binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033343</classIRI>
<classLabel>positive regulation of collagen binding</classLabel>
<newAxiom>'positive regulation of collagen binding' SubClassOf 'positively regulates' some 'collagen binding'</newAxiom>
<newAxiom>'positive regulation of collagen binding' SubClassOf 'regulation of collagen binding'</newAxiom>
<newAxiom>'positive regulation of collagen binding' SubClassOf 'positive regulation of binding'</newAxiom>
<newAxiom>'positive regulation of collagen binding' EquivalentTo 'biological regulation' and ('positively regulates' some 'collagen binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032052</classIRI>
<classLabel>bile acid binding</classLabel>
<newAxiom>'bile acid binding' SubClassOf 'has input' some 'bile acid anion'</newAxiom>
<newAxiom>'bile acid binding' SubClassOf 'monocarboxylic acid binding'</newAxiom>
<newAxiom>'bile acid binding' EquivalentTo 'binding' and ('has input' some 'bile acid anion')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004857</classIRI>
<classLabel>enzyme inhibitor activity</classLabel>
<newAxiom>'enzyme inhibitor activity' SubClassOf 'enzyme regulator activity'</newAxiom>
<newAxiom>'enzyme inhibitor activity' SubClassOf 'directly negatively regulates' some 'catalytic activity'</newAxiom>
<newAxiom>'enzyme inhibitor activity' SubClassOf 'molecular function inhibitor activity'</newAxiom>
<newAxiom>'enzyme inhibitor activity' EquivalentTo 'molecular function regulator activity' and ('directly negatively regulates' some 'catalytic activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032091</classIRI>
<classLabel>negative regulation of protein binding</classLabel>
<newAxiom>'negative regulation of protein binding' SubClassOf 'negative regulation of binding'</newAxiom>
<newAxiom>'negative regulation of protein binding' EquivalentTo 'biological regulation' and ('negatively regulates' some 'protein binding')</newAxiom>
<newAxiom>'negative regulation of protein binding' SubClassOf 'regulation of protein binding'</newAxiom>
<newAxiom>'negative regulation of protein binding' SubClassOf 'negatively regulates' some 'protein binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032092</classIRI>
<classLabel>positive regulation of protein binding</classLabel>
<newAxiom>'positive regulation of protein binding' SubClassOf 'regulation of protein binding'</newAxiom>
<newAxiom>'positive regulation of protein binding' EquivalentTo 'biological regulation' and ('positively regulates' some 'protein binding')</newAxiom>
<newAxiom>'positive regulation of protein binding' SubClassOf 'positive regulation of binding'</newAxiom>
<newAxiom>'positive regulation of protein binding' SubClassOf 'positively regulates' some 'protein binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051100</classIRI>
<classLabel>negative regulation of binding</classLabel>
<newAxiom>'negative regulation of binding' SubClassOf 'regulation of binding'</newAxiom>
<newAxiom>'negative regulation of binding' SubClassOf 'negatively regulates' some 'binding'</newAxiom>
<newAxiom>'negative regulation of binding' SubClassOf 'negative regulation of molecular function'</newAxiom>
<newAxiom>'negative regulation of binding' EquivalentTo 'biological regulation' and ('negatively regulates' some 'binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034637</classIRI>
<classLabel>cellular carbohydrate biosynthetic process</classLabel>
<newAxiom>'cellular carbohydrate biosynthetic process' SubClassOf 'carbohydrate biosynthetic process'</newAxiom>
<newAxiom>'cellular carbohydrate biosynthetic process' SubClassOf 'cellular biosynthetic process'</newAxiom>
<newAxiom>'cellular carbohydrate biosynthetic process' SubClassOf 'cellular carbohydrate metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010675</classIRI>
<classLabel>regulation of cellular carbohydrate metabolic process</classLabel>
<newAxiom>'regulation of cellular carbohydrate metabolic process' SubClassOf 'regulation of cellular metabolic process'</newAxiom>
<newAxiom>'regulation of cellular carbohydrate metabolic process' SubClassOf 'regulates' some 'cellular carbohydrate metabolic process'</newAxiom>
<newAxiom>'regulation of cellular carbohydrate metabolic process' SubClassOf 'regulation of carbohydrate metabolic process'</newAxiom>
<newAxiom>'regulation of cellular carbohydrate metabolic process' EquivalentTo 'biological regulation' and ('regulates' some 'cellular carbohydrate metabolic process')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010676</classIRI>
<classLabel>positive regulation of cellular carbohydrate metabolic process</classLabel>
<newAxiom>'positive regulation of cellular carbohydrate metabolic process' SubClassOf 'positive regulation of cellular metabolic process'</newAxiom>
<newAxiom>'positive regulation of cellular carbohydrate metabolic process' SubClassOf 'positively regulates' some 'cellular carbohydrate metabolic process'</newAxiom>
<newAxiom>'positive regulation of cellular carbohydrate metabolic process' SubClassOf 'positive regulation of carbohydrate metabolic process'</newAxiom>
<newAxiom>'positive regulation of cellular carbohydrate metabolic process' EquivalentTo 'biological regulation' and ('positively regulates' some 'cellular carbohydrate metabolic process')</newAxiom>
<newAxiom>'positive regulation of cellular carbohydrate metabolic process' SubClassOf 'regulation of cellular carbohydrate metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010677</classIRI>
<classLabel>negative regulation of cellular carbohydrate metabolic process</classLabel>
<newAxiom>'negative regulation of cellular carbohydrate metabolic process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'cellular carbohydrate metabolic process')</newAxiom>
<newAxiom>'negative regulation of cellular carbohydrate metabolic process' SubClassOf 'negative regulation of cellular metabolic process'</newAxiom>
<newAxiom>'negative regulation of cellular carbohydrate metabolic process' SubClassOf 'negatively regulates' some 'cellular carbohydrate metabolic process'</newAxiom>
<newAxiom>'negative regulation of cellular carbohydrate metabolic process' SubClassOf 'negative regulation of carbohydrate metabolic process'</newAxiom>
<newAxiom>'negative regulation of cellular carbohydrate metabolic process' SubClassOf 'regulation of cellular carbohydrate metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033218</classIRI>
<classLabel>amide binding</classLabel>
<newAxiom>'amide binding' SubClassOf 'has input' some 'amide'</newAxiom>
<newAxiom>'amide binding' SubClassOf 'binding'</newAxiom>
<newAxiom>'amide binding' EquivalentTo 'binding' and ('has input' some 'amide')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008289</classIRI>
<classLabel>lipid binding</classLabel>
<newAxiom>'lipid binding' SubClassOf 'binding'</newAxiom>
<newAxiom>'lipid binding' SubClassOf 'has input' some 'lipid'</newAxiom>
<newAxiom>'lipid binding' EquivalentTo 'binding' and ('has input' some 'lipid')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033293</classIRI>
<classLabel>monocarboxylic acid binding</classLabel>
<newAxiom>'monocarboxylic acid binding' SubClassOf 'carboxylic acid binding'</newAxiom>
<newAxiom>'monocarboxylic acid binding' EquivalentTo 'binding' and ('has input' some 'monocarboxylic acid anion')</newAxiom>
<newAxiom>'monocarboxylic acid binding' SubClassOf 'has input' some 'monocarboxylic acid anion'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045296</classIRI>
<classLabel>cadherin binding</classLabel>
<newAxiom>'cadherin binding' SubClassOf 'cell adhesion molecule binding'</newAxiom>
<newAxiom>'cadherin binding' SubClassOf 'has input' some 'cadherin'</newAxiom>
<newAxiom>'cadherin binding' EquivalentTo 'binding' and ('has input' some 'cadherin')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002054</classIRI>
<classLabel>nucleobase binding</classLabel>
<newAxiom>'nucleobase binding' SubClassOf 'small molecule binding'</newAxiom>
<newAxiom>'nucleobase binding' SubClassOf 'has input' some 'nucleobase'</newAxiom>
<newAxiom>'nucleobase binding' SubClassOf 'heterocyclic compound binding'</newAxiom>
<newAxiom>'nucleobase binding' SubClassOf 'organic cyclic compound binding'</newAxiom>
<newAxiom>'nucleobase binding' EquivalentTo 'binding' and ('has input' some 'nucleobase')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904793</classIRI>
<classLabel>regulation of euchromatin binding</classLabel>
<newAxiom>'regulation of euchromatin binding' SubClassOf 'regulates' some 'euchromatin binding'</newAxiom>
<newAxiom>'regulation of euchromatin binding' EquivalentTo 'biological regulation' and ('regulates' some 'euchromatin binding')</newAxiom>
<newAxiom>'regulation of euchromatin binding' SubClassOf 'regulation of chromatin binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904794</classIRI>
<classLabel>negative regulation of euchromatin binding</classLabel>
<newAxiom>'negative regulation of euchromatin binding' SubClassOf 'negative regulation of chromatin binding'</newAxiom>
<newAxiom>'negative regulation of euchromatin binding' SubClassOf 'regulation of euchromatin binding'</newAxiom>
<newAxiom>'negative regulation of euchromatin binding' SubClassOf 'negatively regulates' some 'euchromatin binding'</newAxiom>
<newAxiom>'negative regulation of euchromatin binding' EquivalentTo 'biological regulation' and ('negatively regulates' some 'euchromatin binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904795</classIRI>
<classLabel>positive regulation of euchromatin binding</classLabel>
<newAxiom>'positive regulation of euchromatin binding' SubClassOf 'regulation of euchromatin binding'</newAxiom>
<newAxiom>'positive regulation of euchromatin binding' SubClassOf 'positive regulation of chromatin binding'</newAxiom>
<newAxiom>'positive regulation of euchromatin binding' EquivalentTo 'biological regulation' and ('positively regulates' some 'euchromatin binding')</newAxiom>
<newAxiom>'positive regulation of euchromatin binding' SubClassOf 'positively regulates' some 'euchromatin binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051098</classIRI>
<classLabel>regulation of binding</classLabel>
<newAxiom>'regulation of binding' EquivalentTo 'biological regulation' and ('regulates' some 'binding')</newAxiom>
<newAxiom>'regulation of binding' SubClassOf 'regulates' some 'binding'</newAxiom>
<newAxiom>'regulation of binding' SubClassOf 'regulation of molecular function'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051099</classIRI>
<classLabel>positive regulation of binding</classLabel>
<newAxiom>'positive regulation of binding' EquivalentTo 'biological regulation' and ('positively regulates' some 'binding')</newAxiom>
<newAxiom>'positive regulation of binding' SubClassOf 'regulation of binding'</newAxiom>
<newAxiom>'positive regulation of binding' SubClassOf 'positive regulation of molecular function'</newAxiom>
<newAxiom>'positive regulation of binding' SubClassOf 'positively regulates' some 'binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051059</classIRI>
<classLabel>NF-kappaB binding</classLabel>
<newAxiom>'NF-kappaB binding' SubClassOf 'RNA polymerase II-specific DNA-binding transcription factor binding'</newAxiom>
<newAxiom>'NF-kappaB binding' EquivalentTo 'binding' and ('has input' some 'transcription factor NF-kappa-B subunit')</newAxiom>
<newAxiom>'NF-kappaB binding' SubClassOf 'has input' some 'transcription factor NF-kappa-B subunit'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008134</classIRI>
<classLabel>transcription factor binding</classLabel>
<newAxiom>'transcription factor binding' SubClassOf 'protein binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045182</classIRI>
<classLabel>translation regulator activity</classLabel>
<newAxiom>'translation regulator activity' EquivalentTo 'molecular_function' and ('part of' some 'regulation of translation')</newAxiom>
<newAxiom>'translation regulator activity' SubClassOf 'molecular_function'</newAxiom>
<newAxiom>'translation regulator activity' SubClassOf 'part of' some 'regulation of translation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070051</classIRI>
<classLabel>fibrinogen binding</classLabel>
<newAxiom>'fibrinogen binding' SubClassOf 'has input' some 'fibrinogen complex'</newAxiom>
<newAxiom>'fibrinogen binding' SubClassOf 'protein-containing complex binding'</newAxiom>
<newAxiom>'fibrinogen binding' EquivalentTo 'binding' and ('has input' some 'fibrinogen complex')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016597</classIRI>
<classLabel>amino acid binding</classLabel>
<newAxiom>'amino acid binding' SubClassOf 'has input' some 'amino acid'</newAxiom>
<newAxiom>'amino acid binding' SubClassOf 'organic acid binding'</newAxiom>
<newAxiom>'amino acid binding' EquivalentTo 'binding' and ('has input' some 'amino acid')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016595</classIRI>
<classLabel>glutamate binding</classLabel>
<newAxiom>'glutamate binding' SubClassOf 'carboxylic acid binding'</newAxiom>
<newAxiom>'glutamate binding' SubClassOf 'has input' some 'glutamate(1-)'</newAxiom>
<newAxiom>'glutamate binding' EquivalentTo 'binding' and ('has input' some 'glutamate(1-)')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008017</classIRI>
<classLabel>microtubule binding</classLabel>
<newAxiom>'microtubule binding' SubClassOf 'has input' some 'microtubule'</newAxiom>
<newAxiom>'microtubule binding' SubClassOf 'tubulin binding'</newAxiom>
<newAxiom>'microtubule binding' EquivalentTo 'binding' and ('has input' some 'microtubule')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008047</classIRI>
<classLabel>enzyme activator activity</classLabel>
<newAxiom>'enzyme activator activity' SubClassOf 'directly positively regulates' some 'catalytic activity'</newAxiom>
<newAxiom>'enzyme activator activity' SubClassOf 'molecular function activator activity'</newAxiom>
<newAxiom>'enzyme activator activity' SubClassOf 'enzyme regulator activity'</newAxiom>
<newAxiom>'enzyme activator activity' EquivalentTo 'molecular function regulator activity' and ('directly positively regulates' some 'catalytic activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008092</classIRI>
<classLabel>cytoskeletal protein binding</classLabel>
<newAxiom>'cytoskeletal protein binding' SubClassOf 'protein binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001069</classIRI>
<classLabel>glycogen binding</classLabel>
<newAxiom>'glycogen binding' SubClassOf 'has input' some 'glycogen'</newAxiom>
<newAxiom>'glycogen binding' SubClassOf 'polysaccharide binding'</newAxiom>
<newAxiom>'glycogen binding' EquivalentTo 'binding' and ('has input' some 'glycogen')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035563</classIRI>
<classLabel>positive regulation of chromatin binding</classLabel>
<newAxiom>'positive regulation of chromatin binding' EquivalentTo 'biological regulation' and ('positively regulates' some 'chromatin binding')</newAxiom>
<newAxiom>'positive regulation of chromatin binding' SubClassOf 'positive regulation of binding'</newAxiom>
<newAxiom>'positive regulation of chromatin binding' SubClassOf 'positively regulates' some 'chromatin binding'</newAxiom>
<newAxiom>'positive regulation of chromatin binding' SubClassOf 'regulation of chromatin binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035561</classIRI>
<classLabel>regulation of chromatin binding</classLabel>
<newAxiom>'regulation of chromatin binding' EquivalentTo 'biological regulation' and ('regulates' some 'chromatin binding')</newAxiom>
<newAxiom>'regulation of chromatin binding' SubClassOf 'regulates' some 'chromatin binding'</newAxiom>
<newAxiom>'regulation of chromatin binding' SubClassOf 'regulation of binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035562</classIRI>
<classLabel>negative regulation of chromatin binding</classLabel>
<newAxiom>'negative regulation of chromatin binding' SubClassOf 'regulation of chromatin binding'</newAxiom>
<newAxiom>'negative regulation of chromatin binding' SubClassOf 'negative regulation of binding'</newAxiom>
<newAxiom>'negative regulation of chromatin binding' SubClassOf 'negatively regulates' some 'chromatin binding'</newAxiom>
<newAxiom>'negative regulation of chromatin binding' EquivalentTo 'biological regulation' and ('negatively regulates' some 'chromatin binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060548</classIRI>
<classLabel>negative regulation of cell death</classLabel>
<newAxiom>'negative regulation of cell death' EquivalentTo 'biological regulation' and ('negatively regulates' some 'cell death')</newAxiom>
<newAxiom>'negative regulation of cell death' SubClassOf 'regulation of cell death'</newAxiom>
<newAxiom>'negative regulation of cell death' SubClassOf 'negative regulation of cellular process'</newAxiom>
<newAxiom>'negative regulation of cell death' SubClassOf 'negatively regulates' some 'cell death'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901338</classIRI>
<classLabel>catecholamine binding</classLabel>
<newAxiom>'catecholamine binding' EquivalentTo 'binding' and ('has input' some 'catecholamine')</newAxiom>
<newAxiom>'catecholamine binding' SubClassOf 'organic cyclic compound binding'</newAxiom>
<newAxiom>'catecholamine binding' SubClassOf 'has input' some 'catecholamine'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005539</classIRI>
<classLabel>glycosaminoglycan binding</classLabel>
<newAxiom>'glycosaminoglycan binding' SubClassOf 'carbohydrate derivative binding'</newAxiom>
<newAxiom>'glycosaminoglycan binding' SubClassOf 'has input' some 'glycosaminoglycan'</newAxiom>
<newAxiom>'glycosaminoglycan binding' EquivalentTo 'binding' and ('has input' some 'glycosaminoglycan')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005540</classIRI>
<classLabel>hyaluronic acid binding</classLabel>
<newAxiom>'hyaluronic acid binding' EquivalentTo 'binding' and ('has input' some 'hyaluronic acid')</newAxiom>
<newAxiom>'hyaluronic acid binding' SubClassOf 'glycosaminoglycan binding'</newAxiom>
<newAxiom>'hyaluronic acid binding' SubClassOf 'has input' some 'hyaluronic acid'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097690</classIRI>
<classLabel>iron ion transmembrane transporter inhibitor activity</classLabel>
<newAxiom>'iron ion transmembrane transporter inhibitor activity' SubClassOf 'directly negatively regulates' some 'iron ion transmembrane transporter activity'</newAxiom>
<newAxiom>'iron ion transmembrane transporter inhibitor activity' SubClassOf 'molecular function inhibitor activity'</newAxiom>
<newAxiom>'iron ion transmembrane transporter inhibitor activity' EquivalentTo 'molecular function regulator activity' and ('directly negatively regulates' some 'iron ion transmembrane transporter activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042562</classIRI>
<classLabel>hormone binding</classLabel>
<newAxiom>'hormone binding' SubClassOf 'binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061629</classIRI>
<classLabel>RNA polymerase II-specific DNA-binding transcription factor binding</classLabel>
<newAxiom>'RNA polymerase II-specific DNA-binding transcription factor binding' SubClassOf 'DNA-binding transcription factor binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900120</classIRI>
<classLabel>regulation of receptor binding</classLabel>
<newAxiom>'regulation of receptor binding' SubClassOf 'regulates' some 'signaling receptor binding'</newAxiom>
<newAxiom>'regulation of receptor binding' SubClassOf 'regulation of protein binding'</newAxiom>
<newAxiom>'regulation of receptor binding' EquivalentTo 'biological regulation' and ('regulates' some 'signaling receptor binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900121</classIRI>
<classLabel>negative regulation of receptor binding</classLabel>
<newAxiom>'negative regulation of receptor binding' EquivalentTo 'biological regulation' and ('negatively regulates' some 'signaling receptor binding')</newAxiom>
<newAxiom>'negative regulation of receptor binding' SubClassOf 'negative regulation of protein binding'</newAxiom>
<newAxiom>'negative regulation of receptor binding' SubClassOf 'regulation of receptor binding'</newAxiom>
<newAxiom>'negative regulation of receptor binding' SubClassOf 'negatively regulates' some 'signaling receptor binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900122</classIRI>
<classLabel>positive regulation of receptor binding</classLabel>
<newAxiom>'positive regulation of receptor binding' SubClassOf 'positive regulation of protein binding'</newAxiom>
<newAxiom>'positive regulation of receptor binding' SubClassOf 'positively regulates' some 'signaling receptor binding'</newAxiom>
<newAxiom>'positive regulation of receptor binding' SubClassOf 'regulation of receptor binding'</newAxiom>
<newAxiom>'positive regulation of receptor binding' EquivalentTo 'biological regulation' and ('positively regulates' some 'signaling receptor binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005506</classIRI>
<classLabel>iron ion binding</classLabel>
<newAxiom>'iron ion binding' SubClassOf 'transition metal ion binding'</newAxiom>
<newAxiom>'iron ion binding' EquivalentTo 'binding' and ('has input' some 'iron cation')</newAxiom>
<newAxiom>'iron ion binding' SubClassOf 'has input' some 'iron cation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900130</classIRI>
<classLabel>regulation of lipid binding</classLabel>
<newAxiom>'regulation of lipid binding' SubClassOf 'regulation of binding'</newAxiom>
<newAxiom>'regulation of lipid binding' SubClassOf 'regulates' some 'lipid binding'</newAxiom>
<newAxiom>'regulation of lipid binding' EquivalentTo 'biological regulation' and ('regulates' some 'lipid binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900131</classIRI>
<classLabel>negative regulation of lipid binding</classLabel>
<newAxiom>'negative regulation of lipid binding' EquivalentTo 'biological regulation' and ('negatively regulates' some 'lipid binding')</newAxiom>
<newAxiom>'negative regulation of lipid binding' SubClassOf 'negative regulation of binding'</newAxiom>
<newAxiom>'negative regulation of lipid binding' SubClassOf 'negatively regulates' some 'lipid binding'</newAxiom>
<newAxiom>'negative regulation of lipid binding' SubClassOf 'regulation of lipid binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900132</classIRI>
<classLabel>positive regulation of lipid binding</classLabel>
<newAxiom>'positive regulation of lipid binding' SubClassOf 'positive regulation of binding'</newAxiom>
<newAxiom>'positive regulation of lipid binding' EquivalentTo 'biological regulation' and ('positively regulates' some 'lipid binding')</newAxiom>
<newAxiom>'positive regulation of lipid binding' SubClassOf 'regulation of lipid binding'</newAxiom>
<newAxiom>'positive regulation of lipid binding' SubClassOf 'positively regulates' some 'lipid binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005515</classIRI>
<classLabel>protein binding</classLabel>
<newAxiom>'protein binding' EquivalentTo 'binding' and ('has input' some 'protein')</newAxiom>
<newAxiom>'protein binding' SubClassOf 'binding'</newAxiom>
<newAxiom>'protein binding' SubClassOf 'has input' some 'protein'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005518</classIRI>
<classLabel>collagen binding</classLabel>
<newAxiom>'collagen binding' EquivalentTo 'binding' and ('has input' some 'collagen trimer')</newAxiom>
<newAxiom>'collagen binding' SubClassOf 'has input' some 'collagen trimer'</newAxiom>
<newAxiom>'collagen binding' SubClassOf 'protein-containing complex binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005536</classIRI>
<classLabel>glucose binding</classLabel>
<newAxiom>'glucose binding' SubClassOf 'monosaccharide binding'</newAxiom>
<newAxiom>'glucose binding' EquivalentTo 'binding' and ('has input' some 'glucose')</newAxiom>
<newAxiom>'glucose binding' SubClassOf 'has input' some 'glucose'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901363</classIRI>
<classLabel>heterocyclic compound binding</classLabel>
<newAxiom>'heterocyclic compound binding' SubClassOf 'has input' some 'heterocyclic compound'</newAxiom>
<newAxiom>'heterocyclic compound binding' EquivalentTo 'binding' and ('has input' some 'heterocyclic compound')</newAxiom>
<newAxiom>'heterocyclic compound binding' SubClassOf 'binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005488</classIRI>
<classLabel>binding</classLabel>
<newAxiom>'binding' SubClassOf 'molecular_function'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005496</classIRI>
<classLabel>steroid binding</classLabel>
<newAxiom>'steroid binding' SubClassOf 'organic cyclic compound binding'</newAxiom>
<newAxiom>'steroid binding' EquivalentTo 'binding' and ('has input' some 'steroid')</newAxiom>
<newAxiom>'steroid binding' SubClassOf 'lipid binding'</newAxiom>
<newAxiom>'steroid binding' SubClassOf 'has input' some 'steroid'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050839</classIRI>
<classLabel>cell adhesion molecule binding</classLabel>
<newAxiom>'cell adhesion molecule binding' SubClassOf 'protein binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050840</classIRI>
<classLabel>extracellular matrix binding</classLabel>
<newAxiom>'extracellular matrix binding' SubClassOf 'binding'</newAxiom>
<newAxiom>'extracellular matrix binding' SubClassOf 'has input' some 'extracellular matrix'</newAxiom>
<newAxiom>'extracellular matrix binding' EquivalentTo 'binding' and ('has input' some 'extracellular matrix')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098772</classIRI>
<classLabel>molecular function regulator activity</classLabel>
<newAxiom>'molecular function regulator activity' EquivalentTo 'molecular_function' and ('directly regulates' some 'molecular_function')</newAxiom>
<newAxiom>'molecular function regulator activity' SubClassOf 'has_part' some 'protein binding'</newAxiom>
<newAxiom>'molecular function regulator activity' SubClassOf 'directly regulates' some 'molecular_function'</newAxiom>
<newAxiom>'molecular function regulator activity' SubClassOf 'molecular_function'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000112</classIRI>
<classLabel>regulation of cellular macromolecule biosynthetic process</classLabel>
<newAxiom>'regulation of cellular macromolecule biosynthetic process' EquivalentTo 'biological regulation' and ('regulates' some 'cellular macromolecule biosynthetic process')</newAxiom>
<newAxiom>'regulation of cellular macromolecule biosynthetic process' SubClassOf 'regulation of cellular biosynthetic process'</newAxiom>
<newAxiom>'regulation of cellular macromolecule biosynthetic process' SubClassOf 'regulation of macromolecule biosynthetic process'</newAxiom>
<newAxiom>'regulation of cellular macromolecule biosynthetic process' SubClassOf 'regulates' some 'cellular macromolecule biosynthetic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000113</classIRI>
<classLabel>negative regulation of cellular macromolecule biosynthetic process</classLabel>
<newAxiom>'negative regulation of cellular macromolecule biosynthetic process' SubClassOf 'negative regulation of macromolecule biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of cellular macromolecule biosynthetic process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'cellular macromolecule biosynthetic process')</newAxiom>
<newAxiom>'negative regulation of cellular macromolecule biosynthetic process' SubClassOf 'negatively regulates' some 'cellular macromolecule biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of cellular macromolecule biosynthetic process' SubClassOf 'negative regulation of cellular biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of cellular macromolecule biosynthetic process' SubClassOf 'regulation of cellular macromolecule biosynthetic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042301</classIRI>
<classLabel>phosphate ion binding</classLabel>
<newAxiom>'phosphate ion binding' SubClassOf 'anion binding'</newAxiom>
<newAxiom>'phosphate ion binding' SubClassOf 'has input' some 'phosphate ion'</newAxiom>
<newAxiom>'phosphate ion binding' EquivalentTo 'binding' and ('has input' some 'phosphate ion')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042277</classIRI>
<classLabel>peptide binding</classLabel>
<newAxiom>'peptide binding' SubClassOf 'amide binding'</newAxiom>
<newAxiom>'peptide binding' SubClassOf 'has input' some 'peptide'</newAxiom>
<newAxiom>'peptide binding' EquivalentTo 'binding' and ('has input' some 'peptide')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901681</classIRI>
<classLabel>sulfur compound binding</classLabel>
<newAxiom>'sulfur compound binding' SubClassOf 'has input' some 'sulfur molecular entity'</newAxiom>
<newAxiom>'sulfur compound binding' SubClassOf 'binding'</newAxiom>
<newAxiom>'sulfur compound binding' EquivalentTo 'binding' and ('has input' some 'sulfur molecular entity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019825</classIRI>
<classLabel>oxygen binding</classLabel>
<newAxiom>'oxygen binding' SubClassOf 'small molecule binding'</newAxiom>
<newAxiom>'oxygen binding' SubClassOf 'has input' some 'dioxygen'</newAxiom>
<newAxiom>'oxygen binding' EquivalentTo 'binding' and ('has input' some 'dioxygen')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044815</classIRI>
<classLabel>DNA packaging complex</classLabel>
<newAxiom>'DNA packaging complex' SubClassOf 'capable of part of' some 'chromosome organization'</newAxiom>
<newAxiom>'DNA packaging complex' SubClassOf 'protein-containing complex'</newAxiom>
<newAxiom>'DNA packaging complex' EquivalentTo 'protein-containing complex' and ('capable of part of' some 'chromosome organization')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150005</classIRI>
<classLabel>enzyme activator complex</classLabel>
<newAxiom>'enzyme activator complex' SubClassOf 'capable of' some 'enzyme activator activity'</newAxiom>
<newAxiom>'enzyme activator complex' EquivalentTo 'protein-containing complex' and ('capable of' some 'enzyme activator activity')</newAxiom>
<newAxiom>'enzyme activator complex' SubClassOf 'protein-containing complex'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098631</classIRI>
<classLabel>cell adhesion mediator activity</classLabel>
<newAxiom>'cell adhesion mediator activity' SubClassOf 'cell adhesion molecule binding'</newAxiom>
<newAxiom>'cell adhesion mediator activity' SubClassOf 'part of' some 'cell adhesion'</newAxiom>
<newAxiom>'cell adhesion mediator activity' EquivalentTo 'binding' and ('part of' some 'cell adhesion')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098632</classIRI>
<classLabel>cell-cell adhesion mediator activity</classLabel>
<newAxiom>'cell-cell adhesion mediator activity' SubClassOf 'part of' some 'cell-cell adhesion'</newAxiom>
<newAxiom>'cell-cell adhesion mediator activity' EquivalentTo 'protein binding' and ('part of' some 'cell-cell adhesion')</newAxiom>
<newAxiom>'cell-cell adhesion mediator activity' SubClassOf 'cell adhesion mediator activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098633</classIRI>
<classLabel>collagen fibril binding</classLabel>
<newAxiom>'collagen fibril binding' SubClassOf 'protein-containing complex binding'</newAxiom>
<newAxiom>'collagen fibril binding' SubClassOf 'has input' some 'banded collagen fibril'</newAxiom>
<newAxiom>'collagen fibril binding' EquivalentTo 'binding' and ('has input' some 'banded collagen fibril')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140677</classIRI>
<classLabel>molecular function activator activity</classLabel>
<newAxiom>'molecular function activator activity' EquivalentTo 'molecular function regulator activity' and ('directly positively regulates' some 'molecular_function')</newAxiom>
<newAxiom>'molecular function activator activity' SubClassOf 'molecular function regulator activity'</newAxiom>
<newAxiom>'molecular function activator activity' SubClassOf 'directly positively regulates' some 'molecular_function'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140678</classIRI>
<classLabel>molecular function inhibitor activity</classLabel>
<newAxiom>'molecular function inhibitor activity' SubClassOf 'directly negatively regulates' some 'molecular_function'</newAxiom>
<newAxiom>'molecular function inhibitor activity' SubClassOf 'molecular function regulator activity'</newAxiom>
<newAxiom>'molecular function inhibitor activity' EquivalentTo 'molecular function regulator activity' and ('directly negatively regulates' some 'molecular_function')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098641</classIRI>
<classLabel>cadherin binding involved in cell-cell adhesion</classLabel>
<newAxiom>'cadherin binding involved in cell-cell adhesion' SubClassOf 'cell-cell adhesion mediator activity'</newAxiom>
<newAxiom>'cadherin binding involved in cell-cell adhesion' EquivalentTo 'cadherin binding' and ('part of' some 'cell-cell adhesion')</newAxiom>
<newAxiom>'cadherin binding involved in cell-cell adhesion' SubClassOf 'cadherin binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030234</classIRI>
<classLabel>enzyme regulator activity</classLabel>
<newAxiom>'enzyme regulator activity' EquivalentTo 'molecular function regulator activity' and ('regulates' some 'catalytic activity')</newAxiom>
<newAxiom>'enzyme regulator activity' SubClassOf 'regulates' some 'catalytic activity'</newAxiom>
<newAxiom>'enzyme regulator activity' SubClassOf 'molecular function regulator activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044877</classIRI>
<classLabel>protein-containing complex binding</classLabel>
<newAxiom>'protein-containing complex binding' EquivalentTo 'binding' and ('has input' some 'protein-containing complex')</newAxiom>
<newAxiom>'protein-containing complex binding' SubClassOf 'binding'</newAxiom>
<newAxiom>'protein-containing complex binding' SubClassOf 'has input' some 'protein-containing complex'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097367</classIRI>
<classLabel>carbohydrate derivative binding</classLabel>
<newAxiom>'carbohydrate derivative binding' EquivalentTo 'binding' and ('has input' some 'carbohydrate derivative')</newAxiom>
<newAxiom>'carbohydrate derivative binding' SubClassOf 'binding'</newAxiom>
<newAxiom>'carbohydrate derivative binding' SubClassOf 'has input' some 'carbohydrate derivative'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030246</classIRI>
<classLabel>carbohydrate binding</classLabel>
<newAxiom>'carbohydrate binding' EquivalentTo 'binding' and ('has input' some 'carbohydrate')</newAxiom>
<newAxiom>'carbohydrate binding' SubClassOf 'has input' some 'carbohydrate'</newAxiom>
<newAxiom>'carbohydrate binding' SubClassOf 'binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030247</classIRI>
<classLabel>polysaccharide binding</classLabel>
<newAxiom>'polysaccharide binding' EquivalentTo 'binding' and ('has input' some 'polysaccharide')</newAxiom>
<newAxiom>'polysaccharide binding' SubClassOf 'has input' some 'polysaccharide'</newAxiom>
<newAxiom>'polysaccharide binding' SubClassOf 'carbohydrate binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043559</classIRI>
<classLabel>insulin binding</classLabel>
<newAxiom>'insulin binding' SubClassOf not ('in taxon' some 'Fungi')</newAxiom>
<newAxiom>'insulin binding' EquivalentTo 'binding' and ('has input' some 'insulin gene translation product')</newAxiom>
<newAxiom>'insulin binding' SubClassOf 'peptide hormone binding'</newAxiom>
<newAxiom>'insulin binding' SubClassOf 'protein binding'</newAxiom>
<newAxiom>'insulin binding' SubClassOf 'has input' some 'insulin gene translation product'</newAxiom>
<newAxiom>'insulin binding' SubClassOf 'in taxon' some (not ('Fungi'))</newAxiom>
<newAxiom>'insulin binding' DisjointWith 'in taxon' some 'Fungi'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042166</classIRI>
<classLabel>acetylcholine binding</classLabel>
<newAxiom>'acetylcholine binding' EquivalentTo 'binding' and ('has input' some 'acetylcholine')</newAxiom>
<newAxiom>'acetylcholine binding' SubClassOf 'cation binding'</newAxiom>
<newAxiom>'acetylcholine binding' SubClassOf 'neurotransmitter binding'</newAxiom>
<newAxiom>'acetylcholine binding' SubClassOf 'has input' some 'acetylcholine'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042165</classIRI>
<classLabel>neurotransmitter binding</classLabel>
<newAxiom>'neurotransmitter binding' SubClassOf 'binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0023023</classIRI>
<classLabel>MHC protein complex binding</classLabel>
<newAxiom>'MHC protein complex binding' EquivalentTo 'binding' and ('has input' some 'MHC protein complex')</newAxiom>
<newAxiom>'MHC protein complex binding' SubClassOf 'protein-containing complex binding'</newAxiom>
<newAxiom>'MHC protein complex binding' SubClassOf 'has input' some 'MHC protein complex'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0023026</classIRI>
<classLabel>MHC class II protein complex binding</classLabel>
<newAxiom>'MHC class II protein complex binding' EquivalentTo 'binding' and ('has input' some 'MHC class II protein complex')</newAxiom>
<newAxiom>'MHC class II protein complex binding' SubClassOf 'has input' some 'MHC class II protein complex'</newAxiom>
<newAxiom>'MHC class II protein complex binding' SubClassOf 'MHC protein complex binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005102</classIRI>
<classLabel>signaling receptor binding</classLabel>
<newAxiom>'signaling receptor binding' SubClassOf 'protein binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031402</classIRI>
<classLabel>sodium ion binding</classLabel>
<newAxiom>'sodium ion binding' EquivalentTo 'binding' and ('has input' some 'sodium(1+)')</newAxiom>
<newAxiom>'sodium ion binding' SubClassOf 'alkali metal ion binding'</newAxiom>
<newAxiom>'sodium ion binding' SubClassOf 'has input' some 'sodium(1+)'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031406</classIRI>
<classLabel>carboxylic acid binding</classLabel>
<newAxiom>'carboxylic acid binding' EquivalentTo 'binding' and ('has input' some 'carboxylic acid anion')</newAxiom>
<newAxiom>'carboxylic acid binding' SubClassOf 'anion binding'</newAxiom>
<newAxiom>'carboxylic acid binding' SubClassOf 'has input' some 'carboxylic acid anion'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005126</classIRI>
<classLabel>cytokine receptor binding</classLabel>
<newAxiom>'cytokine receptor binding' SubClassOf 'signaling receptor binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905214</classIRI>
<classLabel>regulation of RNA binding</classLabel>
<newAxiom>'regulation of RNA binding' EquivalentTo 'biological regulation' and ('regulates' some 'RNA binding')</newAxiom>
<newAxiom>'regulation of RNA binding' SubClassOf 'regulates' some 'RNA binding'</newAxiom>
<newAxiom>'regulation of RNA binding' SubClassOf 'regulation of binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905215</classIRI>
<classLabel>negative regulation of RNA binding</classLabel>
<newAxiom>'negative regulation of RNA binding' SubClassOf 'negatively regulates' some 'RNA binding'</newAxiom>
<newAxiom>'negative regulation of RNA binding' EquivalentTo 'biological regulation' and ('negatively regulates' some 'RNA binding')</newAxiom>
<newAxiom>'negative regulation of RNA binding' SubClassOf 'negative regulation of binding'</newAxiom>
<newAxiom>'negative regulation of RNA binding' SubClassOf 'regulation of RNA binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905216</classIRI>
<classLabel>positive regulation of RNA binding</classLabel>
<newAxiom>'positive regulation of RNA binding' EquivalentTo 'biological regulation' and ('positively regulates' some 'RNA binding')</newAxiom>
<newAxiom>'positive regulation of RNA binding' SubClassOf 'regulation of RNA binding'</newAxiom>
<newAxiom>'positive regulation of RNA binding' SubClassOf 'positively regulates' some 'RNA binding'</newAxiom>
<newAxiom>'positive regulation of RNA binding' SubClassOf 'positive regulation of binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031420</classIRI>
<classLabel>alkali metal ion binding</classLabel>
<newAxiom>'alkali metal ion binding' EquivalentTo 'binding' and ('has input' some 'alkali metal cation')</newAxiom>
<newAxiom>'alkali metal ion binding' SubClassOf 'metal ion binding'</newAxiom>
<newAxiom>'alkali metal ion binding' SubClassOf 'has input' some 'alkali metal cation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005172</classIRI>
<classLabel>vascular endothelial growth factor receptor binding</classLabel>
<newAxiom>'vascular endothelial growth factor receptor binding' SubClassOf 'has input' some 'vascular endothelial growth factor receptor'</newAxiom>
<newAxiom>'vascular endothelial growth factor receptor binding' SubClassOf 'cytokine receptor binding'</newAxiom>
<newAxiom>'vascular endothelial growth factor receptor binding' EquivalentTo 'binding' and ('has input' some 'vascular endothelial growth factor receptor')</newAxiom>
<newAxiom>'vascular endothelial growth factor receptor binding' SubClassOf 'growth factor receptor binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005173</classIRI>
<classLabel>stem cell factor receptor binding</classLabel>
<newAxiom>'stem cell factor receptor binding' SubClassOf 'has input' some 'mast/stem cell growth factor receptor'</newAxiom>
<newAxiom>'stem cell factor receptor binding' SubClassOf 'cytokine receptor binding'</newAxiom>
<newAxiom>'stem cell factor receptor binding' EquivalentTo 'binding' and ('has input' some 'mast/stem cell growth factor receptor')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043471</classIRI>
<classLabel>regulation of cellular carbohydrate catabolic process</classLabel>
<newAxiom>'regulation of cellular carbohydrate catabolic process' SubClassOf 'regulation of cellular carbohydrate metabolic process'</newAxiom>
<newAxiom>'regulation of cellular carbohydrate catabolic process' SubClassOf 'regulation of carbohydrate catabolic process'</newAxiom>
<newAxiom>'regulation of cellular carbohydrate catabolic process' EquivalentTo 'biological regulation' and ('regulates' some 'cellular carbohydrate catabolic process')</newAxiom>
<newAxiom>'regulation of cellular carbohydrate catabolic process' SubClassOf 'regulates' some 'cellular carbohydrate catabolic process'</newAxiom>
<newAxiom>'regulation of cellular carbohydrate catabolic process' SubClassOf 'regulation of cellular catabolic process'</newAxiom>
<newAxiom>'regulation of cellular carbohydrate catabolic process' SubClassOf 'regulation of macromolecule metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043393</classIRI>
<classLabel>regulation of protein binding</classLabel>
<newAxiom>'regulation of protein binding' SubClassOf 'regulation of binding'</newAxiom>
<newAxiom>'regulation of protein binding' SubClassOf 'regulates' some 'protein binding'</newAxiom>
<newAxiom>'regulation of protein binding' EquivalentTo 'biological regulation' and ('regulates' some 'protein binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120023</classIRI>
<classLabel>somatostatin binding</classLabel>
<newAxiom>'somatostatin binding' SubClassOf 'peptide hormone binding'</newAxiom>
<newAxiom>'somatostatin binding' EquivalentTo 'binding' and ('has input' some 'somatostatin')</newAxiom>
<newAxiom>'somatostatin binding' SubClassOf 'has input' some 'somatostatin'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097159</classIRI>
<classLabel>organic cyclic compound binding</classLabel>
<newAxiom>'organic cyclic compound binding' EquivalentTo 'binding' and ('has input' some 'organic cyclic compound')</newAxiom>
<newAxiom>'organic cyclic compound binding' SubClassOf 'has input' some 'organic cyclic compound'</newAxiom>
<newAxiom>'organic cyclic compound binding' SubClassOf 'binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017046</classIRI>
<classLabel>peptide hormone binding</classLabel>
<newAxiom>'peptide hormone binding' SubClassOf 'hormone binding'</newAxiom>
<newAxiom>'peptide hormone binding' SubClassOf 'has input' some 'peptide hormone'</newAxiom>
<newAxiom>'peptide hormone binding' SubClassOf 'peptide binding'</newAxiom>
<newAxiom>'peptide hormone binding' EquivalentTo 'binding' and ('has input' some 'peptide hormone')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070851</classIRI>
<classLabel>growth factor receptor binding</classLabel>
<newAxiom>'growth factor receptor binding' SubClassOf 'signaling receptor binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048029</classIRI>
<classLabel>monosaccharide binding</classLabel>
<newAxiom>'monosaccharide binding' SubClassOf 'small molecule binding'</newAxiom>
<newAxiom>'monosaccharide binding' SubClassOf 'carbohydrate binding'</newAxiom>
<newAxiom>'monosaccharide binding' SubClassOf 'has input' some 'monosaccharide'</newAxiom>
<newAxiom>'monosaccharide binding' EquivalentTo 'binding' and ('has input' some 'monosaccharide')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036094</classIRI>
<classLabel>small molecule binding</classLabel>
<newAxiom>'small molecule binding' SubClassOf 'binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043176</classIRI>
<classLabel>amine binding</classLabel>
<newAxiom>'amine binding' SubClassOf 'has input' some 'amine'</newAxiom>
<newAxiom>'amine binding' SubClassOf 'binding'</newAxiom>
<newAxiom>'amine binding' EquivalentTo 'binding' and ('has input' some 'amine')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043177</classIRI>
<classLabel>organic acid binding</classLabel>
<newAxiom>'organic acid binding' SubClassOf 'small molecule binding'</newAxiom>
<newAxiom>'organic acid binding' EquivalentTo 'binding' and ('has input' some 'organic acid')</newAxiom>
<newAxiom>'organic acid binding' SubClassOf 'has input' some 'organic acid'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043167</classIRI>
<classLabel>ion binding</classLabel>
<newAxiom>'ion binding' SubClassOf 'binding'</newAxiom>
<newAxiom>'ion binding' EquivalentTo 'binding' and ('has input' some 'ion')</newAxiom>
<newAxiom>'ion binding' SubClassOf 'has input' some 'ion'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043168</classIRI>
<classLabel>anion binding</classLabel>
<newAxiom>'anion binding' SubClassOf 'has input' some 'anion'</newAxiom>
<newAxiom>'anion binding' SubClassOf 'ion binding'</newAxiom>
<newAxiom>'anion binding' EquivalentTo 'binding' and ('has input' some 'anion')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043169</classIRI>
<classLabel>cation binding</classLabel>
<newAxiom>'cation binding' SubClassOf 'has input' some 'cation'</newAxiom>
<newAxiom>'cation binding' EquivalentTo 'binding' and ('has input' some 'cation')</newAxiom>
<newAxiom>'cation binding' SubClassOf 'ion binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043199</classIRI>
<classLabel>sulfate binding</classLabel>
<newAxiom>'sulfate binding' EquivalentTo 'binding' and ('has input' some 'sulfate')</newAxiom>
<newAxiom>'sulfate binding' SubClassOf 'anion binding'</newAxiom>
<newAxiom>'sulfate binding' SubClassOf 'has input' some 'sulfate'</newAxiom>
<newAxiom>'sulfate binding' SubClassOf 'sulfur compound binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043184</classIRI>
<classLabel>vascular endothelial growth factor receptor 2 binding</classLabel>
<newAxiom>'vascular endothelial growth factor receptor 2 binding' SubClassOf 'vascular endothelial growth factor receptor binding'</newAxiom>
<newAxiom>'vascular endothelial growth factor receptor 2 binding' EquivalentTo 'binding' and ('has input' some 'vascular endothelial growth factor receptor 2')</newAxiom>
<newAxiom>'vascular endothelial growth factor receptor 2 binding' SubClassOf 'has input' some 'vascular endothelial growth factor receptor 2'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140297</classIRI>
<classLabel>DNA-binding transcription factor binding</classLabel>
<newAxiom>'DNA-binding transcription factor binding' SubClassOf 'transcription factor binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990239</classIRI>
<classLabel>steroid hormone binding</classLabel>
<newAxiom>'steroid hormone binding' SubClassOf 'steroid binding'</newAxiom>
<newAxiom>'steroid hormone binding' SubClassOf 'hormone binding'</newAxiom>
<newAxiom>'steroid hormone binding' EquivalentTo 'binding' and ('has input' some 'steroid hormone')</newAxiom>
<newAxiom>'steroid hormone binding' SubClassOf 'has input' some 'steroid hormone'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000035</classIRI>
<classLabel>acyl binding</classLabel>
<newAxiom>'acyl binding' SubClassOf 'has input' some 'acyl group'</newAxiom>
<newAxiom>'acyl binding' SubClassOf 'binding'</newAxiom>
<newAxiom>'acyl binding' EquivalentTo 'binding' and ('has input' some 'acyl group')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990188</classIRI>
<classLabel>euchromatin binding</classLabel>
<newAxiom>'euchromatin binding' SubClassOf 'chromatin binding'</newAxiom>
<newAxiom>'euchromatin binding' EquivalentTo 'binding' and ('has input' some 'euchromatin')</newAxiom>
<newAxiom>'euchromatin binding' SubClassOf 'has input' some 'euchromatin'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006073</classIRI>
<classLabel>cellular glucan metabolic process</classLabel>
<newAxiom>'cellular glucan metabolic process' SubClassOf 'cellular polysaccharide metabolic process'</newAxiom>
<newAxiom>'cellular glucan metabolic process' SubClassOf 'glucan metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033692</classIRI>
<classLabel>cellular polysaccharide biosynthetic process</classLabel>
<newAxiom>'cellular polysaccharide biosynthetic process' SubClassOf 'polysaccharide biosynthetic process'</newAxiom>
<newAxiom>'cellular polysaccharide biosynthetic process' SubClassOf 'cellular macromolecule biosynthetic process'</newAxiom>
<newAxiom>'cellular polysaccharide biosynthetic process' SubClassOf 'cellular carbohydrate biosynthetic process'</newAxiom>
<newAxiom>'cellular polysaccharide biosynthetic process' SubClassOf 'cellular polysaccharide metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043021</classIRI>
<classLabel>ribonucleoprotein complex binding</classLabel>
<newAxiom>'ribonucleoprotein complex binding' EquivalentTo 'binding' and ('has input' some 'ribonucleoprotein complex')</newAxiom>
<newAxiom>'ribonucleoprotein complex binding' SubClassOf 'has input' some 'ribonucleoprotein complex'</newAxiom>
<newAxiom>'ribonucleoprotein complex binding' SubClassOf 'protein-containing complex binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043022</classIRI>
<classLabel>ribosome binding</classLabel>
<newAxiom>'ribosome binding' SubClassOf 'has input' some 'ribosome'</newAxiom>
<newAxiom>'ribosome binding' EquivalentTo 'binding' and ('has input' some 'ribosome')</newAxiom>
<newAxiom>'ribosome binding' SubClassOf 'ribonucleoprotein complex binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055072</classIRI>
<classLabel>iron ion homeostasis</classLabel>
<newAxiom>'iron ion homeostasis' SubClassOf 'regulates levels of' some 'iron cation'</newAxiom>
<newAxiom>'iron ion homeostasis' SubClassOf 'monoatomic cation homeostasis'</newAxiom>
<newAxiom>'iron ion homeostasis' SubClassOf 'inorganic ion homeostasis'</newAxiom>
<newAxiom>'iron ion homeostasis' EquivalentTo 'chemical homeostasis' and ('regulates levels of' some 'iron cation')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010941</classIRI>
<classLabel>regulation of cell death</classLabel>
<newAxiom>'regulation of cell death' EquivalentTo 'biological regulation' and ('regulates' some 'cell death')</newAxiom>
<newAxiom>'regulation of cell death' SubClassOf 'regulates' some 'cell death'</newAxiom>
<newAxiom>'regulation of cell death' SubClassOf 'regulation of cellular process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010942</classIRI>
<classLabel>positive regulation of cell death</classLabel>
<newAxiom>'positive regulation of cell death' SubClassOf 'positively regulates' some 'cell death'</newAxiom>
<newAxiom>'positive regulation of cell death' SubClassOf 'regulation of cell death'</newAxiom>
<newAxiom>'positive regulation of cell death' EquivalentTo 'biological regulation' and ('positively regulates' some 'cell death')</newAxiom>
<newAxiom>'positive regulation of cell death' SubClassOf 'positive regulation of cellular process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046914</classIRI>
<classLabel>transition metal ion binding</classLabel>
<newAxiom>'transition metal ion binding' EquivalentTo 'binding' and ('has input' some 'transition element cation')</newAxiom>
<newAxiom>'transition metal ion binding' SubClassOf 'has input' some 'transition element cation'</newAxiom>
<newAxiom>'transition metal ion binding' SubClassOf 'metal ion binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046906</classIRI>
<classLabel>tetrapyrrole binding</classLabel>
<newAxiom>'tetrapyrrole binding' SubClassOf 'heterocyclic compound binding'</newAxiom>
<newAxiom>'tetrapyrrole binding' EquivalentTo 'binding' and ('has input' some 'tetrapyrrole')</newAxiom>
<newAxiom>'tetrapyrrole binding' SubClassOf 'organic cyclic compound binding'</newAxiom>
<newAxiom>'tetrapyrrole binding' SubClassOf 'has input' some 'tetrapyrrole'</newAxiom>
</deletedClass>
</deletedClasses>
</diffReport>