<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
461
</numberChangedClasses>
<numberNewClasses>
21
</numberNewClasses>
<numberDeletedClasses>
183
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046873</classIRI>
<classLabel>metal ion transmembrane transporter activity</classLabel>
<newAxiom>&apos;metal ion transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0086093</classIRI>
<classLabel>G protein-coupled acetylcholine receptor signaling pathway involved in heart process</classLabel>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor signaling pathway involved in heart process&apos; SubClassOf &apos;G protein-coupled receptor signaling pathway involved in heart process&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor signaling pathway involved in heart process&apos; EquivalentTo &apos;G protein-coupled acetylcholine receptor signaling pathway&apos; and (&apos;part of&apos; some &apos;heart process&apos;)</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor signaling pathway involved in heart process&apos; SubClassOf &apos;G protein-coupled acetylcholine receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003729</classIRI>
<classLabel>mouth mucosa</classLabel>
<deletedAxiom>&apos;mouth mucosa&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071887</classIRI>
<classLabel>leukocyte apoptotic process</classLabel>
<newAxiom>&apos;leukocyte apoptotic process&apos; SubClassOf &apos;only in taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;leukocyte apoptotic process&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002407</classIRI>
<classLabel>pericardium</classLabel>
<deletedAxiom>&apos;pericardium&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071874</classIRI>
<classLabel>cellular response to norepinephrine stimulus</classLabel>
<deletedAxiom>&apos;cellular response to norepinephrine stimulus&apos; SubClassOf &apos;cellular response to chemical stimulus&apos;</deletedAxiom>
<newAxiom>&apos;cellular response to norepinephrine stimulus&apos; SubClassOf &apos;cellular response to nitrogen compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071873</classIRI>
<classLabel>response to norepinephrine</classLabel>
<deletedAxiom>&apos;response to norepinephrine&apos; SubClassOf &apos;response to stimulus&apos;</deletedAxiom>
<newAxiom>&apos;response to norepinephrine&apos; SubClassOf &apos;response to organic substance&apos;</newAxiom>
<newAxiom>&apos;response to norepinephrine&apos; SubClassOf &apos;response to nitrogen compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002405</classIRI>
<classLabel>immune system</classLabel>
<deletedAxiom>&apos;immune system&apos; SubClassOf &apos;anatomical system&apos;</deletedAxiom>
<newAxiom>&apos;immune system&apos; SubClassOf http://purl.obolibrary.org/obo/UBERON_0015203</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015711</classIRI>
<classLabel>organic anion transport</classLabel>
<deletedAxiom>&apos;organic anion transport&apos; SubClassOf &apos;anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002418</classIRI>
<classLabel>cartilage tissue</classLabel>
<deletedAxiom>&apos;cartilage tissue&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002423</classIRI>
<classLabel>hepatobiliary system</classLabel>
<deletedAxiom>&apos;hepatobiliary system&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001165</classIRI>
<classLabel>pyloric antrum</classLabel>
<deletedAxiom>&apos;pyloric antrum&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001166</classIRI>
<classLabel>pylorus</classLabel>
<deletedAxiom>&apos;pylorus&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007324</classIRI>
<classLabel>pancreatic lobule</classLabel>
<deletedAxiom>&apos;pancreatic lobule&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0034946</classIRI>
<classLabel>gas excreted from digestive tract</classLabel>
<deletedAxiom>&apos;gas excreted from digestive tract&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0034947</classIRI>
<classLabel>gas in respiratory system</classLabel>
<deletedAxiom>&apos;gas in respiratory system&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0034921</classIRI>
<classLabel>multi organ part structure</classLabel>
<deletedAxiom>&apos;multi organ part structure&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0034929</classIRI>
<classLabel>external soft tissue zone</classLabel>
<deletedAxiom>&apos;external soft tissue zone&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008509</classIRI>
<classLabel>anion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;anion transmembrane transporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;anion&apos;</deletedAxiom>
<deletedAxiom>&apos;anion transmembrane transporter activity&apos; SubClassOf &apos;part of&apos; some &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;anion transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;anion transmembrane transporter activity&apos; SubClassOf &apos;ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002443</classIRI>
<classLabel>leukocyte mediated immunity</classLabel>
<newAxiom>&apos;leukocyte mediated immunity&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;leukocyte mediated immunity&apos; SubClassOf &apos;only in taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008514</classIRI>
<classLabel>organic anion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;organic anion transmembrane transporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;organic anion transmembrane transporter activity&apos; SubClassOf &apos;transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0034905</classIRI>
<classLabel>gland lumen</classLabel>
<deletedAxiom>&apos;gland lumen&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010959</classIRI>
<classLabel>craniocervical muscle</classLabel>
<deletedAxiom>&apos;craniocervical muscle&apos; SubClassOf &apos;part of&apos; some &apos;craniocervical region musculature&apos;</deletedAxiom>
<newAxiom>&apos;craniocervical muscle&apos; SubClassOf &apos;part of&apos; some &apos;craniocervical region musculature&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008528</classIRI>
<classLabel>G protein-coupled peptide receptor activity</classLabel>
<deletedAxiom>&apos;G protein-coupled peptide receptor activity&apos; SubClassOf &apos;G protein-coupled receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled peptide receptor activity&apos; SubClassOf &apos;peptide receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008527</classIRI>
<classLabel>taste receptor activity</classLabel>
<deletedAxiom>&apos;taste receptor activity&apos; SubClassOf &apos;transmembrane signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;taste receptor activity&apos; SubClassOf &apos;part of&apos; some &apos;detection of chemical stimulus involved in sensory perception of taste&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007210</classIRI>
<classLabel>serotonin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;serotonin receptor signaling pathway&apos; SubClassOf &apos;signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;serotonin receptor signaling pathway&apos; EquivalentTo &apos;signal transduction&apos; and (&apos;starts with&apos; some &apos;serotonin receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;serotonin receptor signaling pathway&apos; SubClassOf &apos;part of&apos; some &apos;cellular response to dopamine&apos;</deletedAxiom>
<deletedAxiom>&apos;serotonin receptor signaling pathway&apos; SubClassOf &apos;starts with&apos; some &apos;serotonin receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007213</classIRI>
<classLabel>G protein-coupled acetylcholine receptor signaling pathway</classLabel>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor signaling pathway&apos; EquivalentTo &apos;signal transduction&apos; and (&apos;starts with&apos; some &apos;G protein-coupled acetylcholine receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor signaling pathway&apos; SubClassOf &apos;acetylcholine receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor signaling pathway&apos; SubClassOf &apos;starts with&apos; some &apos;G protein-coupled acetylcholine receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor signaling pathway&apos; SubClassOf &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007215</classIRI>
<classLabel>glutamate receptor signaling pathway</classLabel>
<deletedAxiom>&apos;glutamate receptor signaling pathway&apos; EquivalentTo &apos;signal transduction&apos; and (&apos;starts with&apos; some &apos;glutamate receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;glutamate receptor signaling pathway&apos; SubClassOf &apos;cell surface receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamate receptor signaling pathway&apos; SubClassOf &apos;starts with&apos; some &apos;glutamate receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007216</classIRI>
<classLabel>G protein-coupled glutamate receptor signaling pathway</classLabel>
<deletedAxiom>&apos;G protein-coupled glutamate receptor signaling pathway&apos; SubClassOf &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled glutamate receptor signaling pathway&apos; SubClassOf &apos;starts with&apos; some &apos;G protein-coupled glutamate receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled glutamate receptor signaling pathway&apos; EquivalentTo &apos;signal transduction&apos; and (&apos;starts with&apos; some &apos;G protein-coupled glutamate receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled glutamate receptor signaling pathway&apos; SubClassOf &apos;glutamate receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007218</classIRI>
<classLabel>neuropeptide signaling pathway</classLabel>
<deletedAxiom>&apos;neuropeptide signaling pathway&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Fungi&apos;)</deletedAxiom>
<deletedAxiom>&apos;neuropeptide signaling pathway&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Fungi&apos;))</deletedAxiom>
<deletedAxiom>&apos;neuropeptide signaling pathway&apos; SubClassOf &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;neuropeptide signaling pathway&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062033</classIRI>
<classLabel>positive regulation of mitotic sister chromatid segregation</classLabel>
<deletedAxiom>&apos;positive regulation of mitotic sister chromatid segregation&apos; SubClassOf &apos;positive regulation of cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051380</classIRI>
<classLabel>norepinephrine binding</classLabel>
<deletedAxiom>&apos;norepinephrine binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;norepinephrine binding&apos; SubClassOf &apos;cation binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003830</classIRI>
<classLabel>thoracic segment muscle</classLabel>
<deletedAxiom>&apos;thoracic segment muscle&apos; SubClassOf &apos;part of&apos; some &apos;musculature of thorax&apos;</deletedAxiom>
<newAxiom>&apos;thoracic segment muscle&apos; SubClassOf &apos;part of&apos; some &apos;musculature of thorax&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022853</classIRI>
<classLabel>active ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;active ion transmembrane transporter activity&apos; EquivalentTo &apos;active transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;active ion transmembrane transporter activity&apos; EquivalentTo &apos;active transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003707</classIRI>
<classLabel>nuclear steroid receptor activity</classLabel>
<deletedAxiom>&apos;nuclear steroid receptor activity&apos; SubClassOf &apos;part of&apos; some &apos;steroid hormone mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;nuclear steroid receptor activity&apos; SubClassOf &apos;signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;nuclear steroid receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some &apos;steroid hormone&apos;)</deletedAxiom>
<deletedAxiom>&apos;nuclear steroid receptor activity&apos; SubClassOf &apos;has input&apos; some &apos;steroid hormone&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022890</classIRI>
<classLabel>inorganic cation transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;inorganic cation transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903179</classIRI>
<classLabel>regulation of dopamine biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of dopamine biosynthetic process&apos; SubClassOf &apos;regulates&apos; some &apos;dopamine biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of dopamine biosynthetic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;dopamine biosynthetic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of dopamine biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of dopamine biosynthetic process&apos; SubClassOf &apos;regulation of dopamine metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903181</classIRI>
<classLabel>positive regulation of dopamine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of dopamine biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dopamine biosynthetic process&apos; SubClassOf &apos;positively regulates&apos; some &apos;dopamine biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dopamine biosynthetic process&apos; SubClassOf &apos;positive regulation of dopamine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dopamine biosynthetic process&apos; SubClassOf &apos;regulation of dopamine biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dopamine biosynthetic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;dopamine biosynthetic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903180</classIRI>
<classLabel>negative regulation of dopamine biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of dopamine biosynthetic process&apos; SubClassOf &apos;regulation of dopamine biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dopamine biosynthetic process&apos; SubClassOf &apos;negative regulation of dopamine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dopamine biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dopamine biosynthetic process&apos; SubClassOf &apos;negatively regulates&apos; some &apos;dopamine biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dopamine biosynthetic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;dopamine biosynthetic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007167</classIRI>
<classLabel>enzyme-linked receptor protein signaling pathway</classLabel>
<deletedAxiom>&apos;enzyme-linked receptor protein signaling pathway&apos; SubClassOf &apos;cell surface receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007169</classIRI>
<classLabel>transmembrane receptor protein tyrosine kinase signaling pathway</classLabel>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase signaling pathway&apos; SubClassOf &apos;enzyme-linked receptor protein signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002323</classIRI>
<classLabel>coelemic cavity lumen</classLabel>
<deletedAxiom>&apos;coelemic cavity lumen&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002324</classIRI>
<classLabel>muscle of back</classLabel>
<deletedAxiom>&apos;muscle of back&apos; SubClassOf &apos;part of&apos; some &apos;musculature of back&apos;</deletedAxiom>
<newAxiom>&apos;muscle of back&apos; SubClassOf &apos;part of&apos; some &apos;musculature of back&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_38147</classIRI>
<classLabel>cardiotonic drug</classLabel>
<deletedAxiom>&apos;cardiotonic drug&apos; SubClassOf &apos;cardiovascular drug&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007186</classIRI>
<classLabel>G protein-coupled receptor signaling pathway</classLabel>
<deletedAxiom>&apos;G protein-coupled receptor signaling pathway&apos; EquivalentTo &apos;signal transduction&apos; and (&apos;starts with&apos; some &apos;G protein-coupled receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;starts with&apos; some &apos;G protein-coupled receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004997</classIRI>
<classLabel>mucosa of pyloric antrum</classLabel>
<deletedAxiom>&apos;mucosa of pyloric antrum&apos; SubClassOf &apos;part of&apos; some &apos;mucosa of pylorus&apos;</deletedAxiom>
<newAxiom>&apos;mucosa of pyloric antrum&apos; SubClassOf &apos;part of&apos; some &apos;mucosa of pylorus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001015</classIRI>
<classLabel>musculature</classLabel>
<deletedAxiom>&apos;musculature&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016907</classIRI>
<classLabel>G protein-coupled acetylcholine receptor activity</classLabel>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor activity&apos; SubClassOf &apos;acetylcholine receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor activity&apos; SubClassOf &apos;G protein-coupled amine receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor activity&apos; EquivalentTo &apos;G protein-coupled receptor activity&apos; and (&apos;has input&apos; some &apos;acetylcholine&apos;)</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor activity&apos; SubClassOf &apos;G protein-coupled neurotransmitter receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor activity&apos; SubClassOf &apos;part of&apos; some &apos;G protein-coupled acetylcholine receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004930</classIRI>
<classLabel>G protein-coupled receptor activity</classLabel>
<deletedAxiom>&apos;G protein-coupled receptor activity&apos; SubClassOf &apos;transmembrane signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled receptor activity&apos; SubClassOf &apos;part of&apos; some &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019199</classIRI>
<classLabel>transmembrane receptor protein kinase activity</classLabel>
<deletedAxiom>&apos;transmembrane receptor protein kinase activity&apos; SubClassOf &apos;protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein kinase activity&apos; SubClassOf &apos;transmembrane signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033483</classIRI>
<classLabel>gas homeostasis</classLabel>
<deletedAxiom>&apos;gas homeostasis&apos; SubClassOf &apos;chemical homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004967</classIRI>
<classLabel>glucagon receptor activity</classLabel>
<deletedAxiom>&apos;glucagon receptor activity&apos; SubClassOf &apos;part of&apos; some &apos;cellular response to glucagon stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;glucagon receptor activity&apos; SubClassOf &apos;has input&apos; some &apos;glucagon&apos;</deletedAxiom>
<deletedAxiom>&apos;glucagon receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some &apos;glucagon&apos;)</deletedAxiom>
<deletedAxiom>&apos;glucagon receptor activity&apos; SubClassOf &apos;G protein-coupled peptide receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0014389</classIRI>
<classLabel>gustatory papilla of tongue</classLabel>
<deletedAxiom>&apos;gustatory papilla of tongue&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004993</classIRI>
<classLabel>G protein-coupled serotonin receptor activity</classLabel>
<deletedAxiom>&apos;G protein-coupled serotonin receptor activity&apos; SubClassOf &apos;serotonin receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled serotonin receptor activity&apos; EquivalentTo &apos;G protein-coupled amine receptor activity&apos; and (&apos;has input&apos; some &apos;serotonin(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled serotonin receptor activity&apos; SubClassOf &apos;G protein-coupled amine receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled serotonin receptor activity&apos; SubClassOf &apos;part of&apos; some &apos;G protein-coupled serotonin receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled serotonin receptor activity&apos; SubClassOf &apos;has_part&apos; some &apos;serotonin binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004994</classIRI>
<classLabel>somatostatin receptor activity</classLabel>
<deletedAxiom>&apos;somatostatin receptor activity&apos; SubClassOf &apos;has input&apos; some &apos;somatostatin&apos;</deletedAxiom>
<deletedAxiom>&apos;somatostatin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some &apos;somatostatin&apos;)</deletedAxiom>
<deletedAxiom>&apos;somatostatin receptor activity&apos; SubClassOf &apos;part of&apos; some &apos;somatostatin signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;somatostatin receptor activity&apos; SubClassOf &apos;neuropeptide receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003687</classIRI>
<classLabel>foramen magnum</classLabel>
<deletedAxiom>&apos;foramen magnum&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003684</classIRI>
<classLabel>abdominal cavity</classLabel>
<deletedAxiom>&apos;abdominal cavity&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001032</classIRI>
<classLabel>sensory system</classLabel>
<deletedAxiom>&apos;sensory system&apos; SubClassOf &apos;anatomical system&apos;</deletedAxiom>
<newAxiom>&apos;sensory system&apos; SubClassOf http://purl.obolibrary.org/obo/UBERON_0015203</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002377</classIRI>
<classLabel>muscle of neck</classLabel>
<deletedAxiom>&apos;muscle of neck&apos; SubClassOf &apos;part of&apos; some &apos;musculature of neck&apos;</deletedAxiom>
<newAxiom>&apos;muscle of neck&apos; SubClassOf &apos;part of&apos; some &apos;musculature of neck&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002378</classIRI>
<classLabel>muscle of abdomen</classLabel>
<deletedAxiom>&apos;muscle of abdomen&apos; SubClassOf &apos;part of&apos; some &apos;abdomen musculature&apos;</deletedAxiom>
<newAxiom>&apos;muscle of abdomen&apos; SubClassOf &apos;part of&apos; some &apos;abdomen musculature&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015698</classIRI>
<classLabel>inorganic anion transport</classLabel>
<deletedAxiom>&apos;inorganic anion transport&apos; SubClassOf &apos;anion transport&apos;</deletedAxiom>
<newAxiom>&apos;inorganic anion transport&apos; SubClassOf &apos;transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015695</classIRI>
<classLabel>organic cation transport</classLabel>
<deletedAxiom>&apos;organic cation transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002385</classIRI>
<classLabel>muscle tissue</classLabel>
<deletedAxiom>&apos;muscle tissue&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0019207</classIRI>
<classLabel>chorioretinal region</classLabel>
<deletedAxiom>&apos;chorioretinal region&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009842</classIRI>
<classLabel>glandular acinus</classLabel>
<deletedAxiom>&apos;glandular acinus&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009755</classIRI>
<classLabel>hormone-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;hormone-mediated signaling pathway&apos; SubClassOf &apos;part of&apos; some &apos;cellular response to hormone stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;hormone-mediated signaling pathway&apos; SubClassOf &apos;signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003716</classIRI>
<classLabel>recurrent laryngeal nerve</classLabel>
<newAxiom>&apos;recurrent laryngeal nerve&apos; SubClassOf &apos;structure with developmental contribution from neural crest&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003714</classIRI>
<classLabel>neural tissue</classLabel>
<deletedAxiom>&apos;neural tissue&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_59905</classIRI>
<classLabel>dopaminium(1+)</classLabel>
<deletedAxiom>&apos;dopaminium(1+)&apos; SubClassOf &apos;has role&apos; some &apos;human metabolite&apos;</deletedAxiom>
<deletedAxiom>&apos;dopaminium(1+)&apos; SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of some &apos;dopamine&apos;</deletedAxiom>
<deletedAxiom>&apos;dopaminium(1+)&apos; SubClassOf &apos;ammonium ion derivative&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046716</classIRI>
<classLabel>muscle cell cellular homeostasis</classLabel>
<deletedAxiom>&apos;muscle cell cellular homeostasis&apos; SubClassOf &apos;anatomical structure homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010890</classIRI>
<classLabel>pelvic complex muscle</classLabel>
<deletedAxiom>&apos;pelvic complex muscle&apos; SubClassOf &apos;part of&apos; some &apos;musculature of pelvic complex&apos;</deletedAxiom>
<newAxiom>&apos;pelvic complex muscle&apos; SubClassOf &apos;part of&apos; some &apos;musculature of pelvic complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010891</classIRI>
<classLabel>pectoral complex muscle</classLabel>
<deletedAxiom>&apos;pectoral complex muscle&apos; SubClassOf &apos;part of&apos; some &apos;musculature of pectoral complex&apos;</deletedAxiom>
<newAxiom>&apos;pectoral complex muscle&apos; SubClassOf &apos;part of&apos; some &apos;musculature of pectoral complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034755</classIRI>
<classLabel>iron ion transmembrane transport</classLabel>
<newAxiom>&apos;iron ion transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007159</classIRI>
<classLabel>leukocyte cell-cell adhesion</classLabel>
<deletedAxiom>&apos;leukocyte cell-cell adhesion&apos; SubClassOf &apos;only in taxon&apos; some &apos;Metazoa&apos;</deletedAxiom>
<newAxiom>&apos;leukocyte cell-cell adhesion&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;leukocyte cell-cell adhesion&apos; SubClassOf &apos;only in taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007059</classIRI>
<classLabel>chromosome segregation</classLabel>
<deletedAxiom>&apos;chromosome segregation&apos; SubClassOf &apos;cellular process&apos;</deletedAxiom>
<newAxiom>&apos;chromosome segregation&apos; SubClassOf &apos;cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046627</classIRI>
<classLabel>negative regulation of insulin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of insulin receptor signaling pathway&apos; SubClassOf &apos;regulation of insulin receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of insulin receptor signaling pathway&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of insulin receptor signaling pathway&apos; SubClassOf &apos;negative regulation of cellular response to insulin stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of insulin receptor signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;insulin receptor signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of insulin receptor signaling pathway&apos; SubClassOf &apos;negatively regulates&apos; some &apos;insulin receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046626</classIRI>
<classLabel>regulation of insulin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of insulin receptor signaling pathway&apos; SubClassOf &apos;regulation of signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of insulin receptor signaling pathway&apos; SubClassOf &apos;regulates&apos; some &apos;insulin receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of insulin receptor signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;insulin receptor signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of insulin receptor signaling pathway&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of insulin receptor signaling pathway&apos; SubClassOf &apos;only in taxon&apos; some &apos;Eumetazoa&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046628</classIRI>
<classLabel>positive regulation of insulin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of insulin receptor signaling pathway&apos; SubClassOf &apos;regulation of insulin receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of insulin receptor signaling pathway&apos; SubClassOf &apos;positively regulates&apos; some &apos;insulin receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of insulin receptor signaling pathway&apos; SubClassOf &apos;positive regulation of cellular response to insulin stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of insulin receptor signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;insulin receptor signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of insulin receptor signaling pathway&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045321</classIRI>
<classLabel>leukocyte activation</classLabel>
<newAxiom>&apos;leukocyte activation&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;leukocyte activation&apos; SubClassOf &apos;only in taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002224</classIRI>
<classLabel>thoracic cavity</classLabel>
<deletedAxiom>&apos;thoracic cavity&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099145</classIRI>
<classLabel>regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane</classLabel>
<deletedAxiom>&apos;regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane&apos; SubClassOf &apos;regulation of receptor localization to synapse&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;exocytic insertion of neurotransmitter receptor to postsynaptic membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane&apos; SubClassOf &apos;regulation of protein transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane&apos; SubClassOf &apos;regulation of protein localization to membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane&apos; SubClassOf &apos;regulation of protein localization to cell periphery&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane&apos; SubClassOf &apos;regulates&apos; some &apos;exocytic insertion of neurotransmitter receptor to postsynaptic membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane&apos; SubClassOf &apos;regulation of exocytosis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032052</classIRI>
<classLabel>bile acid binding</classLabel>
<deletedAxiom>&apos;bile acid binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;bile acid binding&apos; SubClassOf &apos;monocarboxylic acid binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004860</classIRI>
<classLabel>protein kinase inhibitor activity</classLabel>
<deletedAxiom>&apos;protein kinase inhibitor activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein kinase inhibitor activity&apos; SubClassOf &apos;kinase inhibitor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein kinase inhibitor activity&apos; EquivalentTo &apos;molecular function inhibitor activity&apos; and (&apos;negatively regulates&apos; some &apos;protein kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;protein kinase inhibitor activity&apos; SubClassOf &apos;protein kinase regulator activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002294</classIRI>
<classLabel>biliary system</classLabel>
<deletedAxiom>&apos;biliary system&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044070</classIRI>
<classLabel>regulation of anion transport</classLabel>
<deletedAxiom>&apos;regulation of anion transport&apos; SubClassOf &apos;regulation of ion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of anion transport&apos; SubClassOf &apos;regulates&apos; some &apos;anion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of anion transport&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;anion transport&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004888</classIRI>
<classLabel>transmembrane signaling receptor activity</classLabel>
<deletedAxiom>&apos;transmembrane signaling receptor activity&apos; SubClassOf &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002257</classIRI>
<classLabel>ventral horn of spinal cord</classLabel>
<newAxiom>&apos;ventral horn of spinal cord&apos; SubClassOf &apos;lateral structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003593</classIRI>
<classLabel>thoracic cavity connective tissue</classLabel>
<deletedAxiom>&apos;thoracic cavity connective tissue&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010743</classIRI>
<classLabel>meningeal cluster</classLabel>
<deletedAxiom>&apos;meningeal cluster&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0034713</classIRI>
<classLabel>cranial neuron projection bundle</classLabel>
<newAxiom>&apos;cranial neuron projection bundle&apos; SubClassOf &apos;lateral structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015464</classIRI>
<classLabel>acetylcholine receptor activity</classLabel>
<deletedAxiom>&apos;acetylcholine receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some &apos;acetylcholine&apos;)</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor activity&apos; SubClassOf &apos;part of&apos; some &apos;synaptic transmission, cholinergic&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor activity&apos; SubClassOf &apos;postsynaptic neurotransmitter receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor activity&apos; SubClassOf &apos;transmembrane signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor activity&apos; SubClassOf &apos;has_part&apos; some &apos;acetylcholine binding&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor activity&apos; SubClassOf &apos;has input&apos; some &apos;acetylcholine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903350</classIRI>
<classLabel>response to dopamine</classLabel>
<deletedAxiom>&apos;response to dopamine&apos; SubClassOf &apos;response to nitrogen compound&apos;</deletedAxiom>
<deletedAxiom>&apos;response to dopamine&apos; SubClassOf &apos;has input&apos; some &apos;dopaminium(1+)&apos;</deletedAxiom>
<deletedAxiom>&apos;response to dopamine&apos; EquivalentTo &apos;response to stimulus&apos; and (&apos;has input&apos; some &apos;dopaminium(1+)&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903351</classIRI>
<classLabel>cellular response to dopamine</classLabel>
<deletedAxiom>&apos;cellular response to dopamine&apos; SubClassOf &apos;cellular response to nitrogen compound&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular response to dopamine&apos; EquivalentTo &apos;cellular response to chemical stimulus&apos; and (&apos;has input&apos; some &apos;dopaminium(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;cellular response to dopamine&apos; SubClassOf &apos;response to dopamine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009715</classIRI>
<classLabel>stomodeal lumen</classLabel>
<deletedAxiom>&apos;stomodeal lumen&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038169</classIRI>
<classLabel>somatostatin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;somatostatin receptor signaling pathway&apos; SubClassOf &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038187</classIRI>
<classLabel>pattern recognition receptor activity</classLabel>
<deletedAxiom>&apos;pattern recognition receptor activity&apos; SubClassOf &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038170</classIRI>
<classLabel>somatostatin signaling pathway</classLabel>
<deletedAxiom>&apos;somatostatin signaling pathway&apos; SubClassOf &apos;has input&apos; some &apos;somatostatin&apos;</deletedAxiom>
<deletedAxiom>&apos;somatostatin signaling pathway&apos; SubClassOf &apos;somatostatin receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;somatostatin signaling pathway&apos; SubClassOf &apos;hormone-mediated signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099124</classIRI>
<classLabel>axonal dopamine secretion</classLabel>
<deletedAxiom>&apos;axonal dopamine secretion&apos; SubClassOf &apos;dopamine secretion&apos;</deletedAxiom>
<deletedAxiom>&apos;axonal dopamine secretion&apos; SubClassOf &apos;occurs in&apos; some &apos;axon&apos;</deletedAxiom>
<deletedAxiom>&apos;axonal dopamine secretion&apos; EquivalentTo &apos;dopamine secretion&apos; and (&apos;occurs in&apos; some &apos;axon&apos;)</deletedAxiom>
<deletedAxiom>&apos;axonal dopamine secretion&apos; SubClassOf &apos;establishment of localization in cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099123</classIRI>
<classLabel>somato-dendritic dopamine secretion</classLabel>
<deletedAxiom>&apos;somato-dendritic dopamine secretion&apos; SubClassOf &apos;dopamine secretion&apos;</deletedAxiom>
<deletedAxiom>&apos;somato-dendritic dopamine secretion&apos; SubClassOf &apos;occurs in&apos; some &apos;somatodendritic compartment&apos;</deletedAxiom>
<deletedAxiom>&apos;somato-dendritic dopamine secretion&apos; SubClassOf &apos;establishment of localization in cell&apos;</deletedAxiom>
<deletedAxiom>&apos;somato-dendritic dopamine secretion&apos; EquivalentTo &apos;dopamine secretion&apos; and (&apos;occurs in&apos; some &apos;somatodendritic compartment&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008324</classIRI>
<classLabel>cation transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;cation transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;cation transmembrane transporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;cation&apos;</deletedAxiom>
<newAxiom>&apos;cation transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
<newAxiom>&apos;cation transmembrane transporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;monoatomic cation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007148</classIRI>
<classLabel>lumen of hindgut</classLabel>
<deletedAxiom>&apos;lumen of hindgut&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007147</classIRI>
<classLabel>lumen of midgut</classLabel>
<deletedAxiom>&apos;lumen of midgut&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007159</classIRI>
<classLabel>lumen of colon</classLabel>
<deletedAxiom>&apos;lumen of colon&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007158</classIRI>
<classLabel>lumen of anal canal</classLabel>
<deletedAxiom>&apos;lumen of anal canal&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099072</classIRI>
<classLabel>regulation of postsynaptic membrane neurotransmitter receptor levels</classLabel>
<deletedAxiom>&apos;regulation of postsynaptic membrane neurotransmitter receptor levels&apos; SubClassOf &apos;regulation of biological quality&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045211</classIRI>
<classLabel>postsynaptic membrane</classLabel>
<deletedAxiom>&apos;postsynaptic membrane&apos; SubClassOf &apos;part of&apos; some &apos;postsynapse&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic membrane&apos; SubClassOf &apos;synaptic membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008277</classIRI>
<classLabel>regulation of G protein-coupled receptor signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;regulates&apos; some &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;regulation of signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of G protein-coupled receptor signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;G protein-coupled receptor signaling pathway&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008286</classIRI>
<classLabel>insulin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;insulin receptor signaling pathway&apos; SubClassOf &apos;part of&apos; some &apos;cellular response to insulin stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor signaling pathway&apos; SubClassOf &apos;only in taxon&apos; some &apos;Eumetazoa&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor signaling pathway&apos; SubClassOf &apos;transmembrane receptor protein tyrosine kinase signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor signaling pathway&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004708</classIRI>
<classLabel>paired limb/fin</classLabel>
<deletedAxiom>&apos;paired limb/fin&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004716</classIRI>
<classLabel>conceptus</classLabel>
<deletedAxiom>&apos;conceptus&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004713</classIRI>
<classLabel>protein tyrosine kinase activity</classLabel>
<deletedAxiom>&apos;protein tyrosine kinase activity&apos; SubClassOf &apos;protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein tyrosine kinase activity&apos; SubClassOf &apos;part of&apos; some &apos;peptidyl-tyrosine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004714</classIRI>
<classLabel>transmembrane receptor protein tyrosine kinase activity</classLabel>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase activity&apos; SubClassOf &apos;transmembrane receptor protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase activity&apos; SubClassOf &apos;protein tyrosine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0095500</classIRI>
<classLabel>acetylcholine receptor signaling pathway</classLabel>
<deletedAxiom>&apos;acetylcholine receptor signaling pathway&apos; SubClassOf &apos;postsynaptic signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor signaling pathway&apos; SubClassOf &apos;starts with&apos; some &apos;acetylcholine receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor signaling pathway&apos; SubClassOf &apos;part of&apos; some &apos;cellular response to acetylcholine&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor signaling pathway&apos; EquivalentTo &apos;signal transduction&apos; and (&apos;starts with&apos; some &apos;acetylcholine receptor activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002185</classIRI>
<classLabel>bronchus</classLabel>
<deletedAxiom>&apos;bronchus&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002186</classIRI>
<classLabel>bronchiole</classLabel>
<deletedAxiom>&apos;bronchiole&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004770</classIRI>
<classLabel>articular system</classLabel>
<deletedAxiom>&apos;articular system&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004786</classIRI>
<classLabel>gastrointestinal system mucosa</classLabel>
<deletedAxiom>&apos;gastrointestinal system mucosa&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016773</classIRI>
<classLabel>phosphotransferase activity, alcohol group as acceptor</classLabel>
<deletedAxiom>&apos;phosphotransferase activity, alcohol group as acceptor&apos; SubClassOf &apos;transferase activity, transferring phosphorus-containing groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002149</classIRI>
<classLabel>superior salivatory nucleus</classLabel>
<newAxiom>&apos;superior salivatory nucleus&apos; SubClassOf &apos;ectoderm-derived structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0011953</classIRI>
<classLabel>stomach glandular region</classLabel>
<deletedAxiom>&apos;stomach glandular region&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014049</classIRI>
<classLabel>positive regulation of glutamate secretion</classLabel>
<deletedAxiom>&apos;positive regulation of glutamate secretion&apos; SubClassOf &apos;positive regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014048</classIRI>
<classLabel>regulation of glutamate secretion</classLabel>
<deletedAxiom>&apos;regulation of glutamate secretion&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014046</classIRI>
<classLabel>dopamine secretion</classLabel>
<deletedAxiom>&apos;dopamine secretion&apos; SubClassOf &apos;dopamine transport&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine secretion&apos; EquivalentTo &apos;secretion&apos; and (&apos;has primary input&apos; some &apos;dopaminium(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;dopamine secretion&apos; SubClassOf &apos;signal release&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014058</classIRI>
<classLabel>negative regulation of acetylcholine secretion, neurotransmission</classLabel>
<deletedAxiom>&apos;negative regulation of acetylcholine secretion, neurotransmission&apos; SubClassOf &apos;negative regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014059</classIRI>
<classLabel>regulation of dopamine secretion</classLabel>
<deletedAxiom>&apos;regulation of dopamine secretion&apos; SubClassOf &apos;regulates&apos; some &apos;dopamine secretion&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of dopamine secretion&apos; SubClassOf &apos;regulation of secretion by cell&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of dopamine secretion&apos; SubClassOf &apos;regulation of ion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of dopamine secretion&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;dopamine secretion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014056</classIRI>
<classLabel>regulation of acetylcholine secretion, neurotransmission</classLabel>
<deletedAxiom>&apos;regulation of acetylcholine secretion, neurotransmission&apos; SubClassOf &apos;regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014057</classIRI>
<classLabel>positive regulation of acetylcholine secretion, neurotransmission</classLabel>
<deletedAxiom>&apos;positive regulation of acetylcholine secretion, neurotransmission&apos; SubClassOf &apos;positive regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038023</classIRI>
<classLabel>signaling receptor activity</classLabel>
<deletedAxiom>&apos;signaling receptor activity&apos; SubClassOf &apos;molecular transducer activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014050</classIRI>
<classLabel>negative regulation of glutamate secretion</classLabel>
<deletedAxiom>&apos;negative regulation of glutamate secretion&apos; SubClassOf &apos;negative regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002199</classIRI>
<classLabel>integument</classLabel>
<deletedAxiom>&apos;integument&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0035965</classIRI>
<classLabel>wall of blood vessel</classLabel>
<deletedAxiom>&apos;wall of blood vessel&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009664</classIRI>
<classLabel>gut mesentery</classLabel>
<deletedAxiom>&apos;gut mesentery&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008227</classIRI>
<classLabel>G protein-coupled amine receptor activity</classLabel>
<deletedAxiom>&apos;G protein-coupled amine receptor activity&apos; SubClassOf &apos;has input&apos; some &apos;amine&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled amine receptor activity&apos; EquivalentTo &apos;G protein-coupled receptor activity&apos; and (&apos;has input&apos; some &apos;amine&apos;)</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled amine receptor activity&apos; SubClassOf &apos;G protein-coupled receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009670</classIRI>
<classLabel>rectal lumen</classLabel>
<deletedAxiom>&apos;rectal lumen&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0036215</classIRI>
<classLabel>anatomical surface region</classLabel>
<deletedAxiom>&apos;anatomical surface region&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0036217</classIRI>
<classLabel>coelomic fluid</classLabel>
<deletedAxiom>&apos;coelomic fluid&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010469</classIRI>
<classLabel>regulation of signaling receptor activity</classLabel>
<deletedAxiom>&apos;regulation of signaling receptor activity&apos; SubClassOf &apos;regulates&apos; some &apos;signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of signaling receptor activity&apos; SubClassOf &apos;regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of signaling receptor activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;signaling receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of signaling receptor activity&apos; SubClassOf &apos;regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001558</classIRI>
<classLabel>lower respiratory tract</classLabel>
<deletedAxiom>&apos;lower respiratory tract&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008188</classIRI>
<classLabel>neuropeptide receptor activity</classLabel>
<deletedAxiom>&apos;neuropeptide receptor activity&apos; SubClassOf &apos;part of&apos; some &apos;neuropeptide signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;neuropeptide receptor activity&apos; SubClassOf &apos;has_part&apos; some &apos;neuropeptide binding&apos;</deletedAxiom>
<deletedAxiom>&apos;neuropeptide receptor activity&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Fungi&apos;)</deletedAxiom>
<deletedAxiom>&apos;neuropeptide receptor activity&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi&apos;</deletedAxiom>
<deletedAxiom>&apos;neuropeptide receptor activity&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Fungi&apos;))</deletedAxiom>
<deletedAxiom>&apos;neuropeptide receptor activity&apos; SubClassOf &apos;G protein-coupled peptide receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0013525</classIRI>
<classLabel>stomach lumen</classLabel>
<deletedAxiom>&apos;stomach lumen&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001568</classIRI>
<classLabel>muscle of larynx</classLabel>
<deletedAxiom>&apos;muscle of larynx&apos; SubClassOf &apos;part of&apos; some &apos;musculature of larynx&apos;</deletedAxiom>
<newAxiom>&apos;muscle of larynx&apos; SubClassOf &apos;part of&apos; some &apos;musculature of larynx&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004672</classIRI>
<classLabel>protein kinase activity</classLabel>
<deletedAxiom>&apos;protein kinase activity&apos; SubClassOf &apos;phosphotransferase activity, alcohol group as acceptor&apos;</deletedAxiom>
<deletedAxiom>&apos;protein kinase activity&apos; SubClassOf &apos;catalytic activity, acting on a protein&apos;</deletedAxiom>
<deletedAxiom>&apos;protein kinase activity&apos; SubClassOf &apos;kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0036244</classIRI>
<classLabel>secretion of serous membrane</classLabel>
<deletedAxiom>&apos;secretion of serous membrane&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042923</classIRI>
<classLabel>neuropeptide binding</classLabel>
<deletedAxiom>&apos;neuropeptide binding&apos; SubClassOf &apos;peptide binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005162</classIRI>
<classLabel>multi cell part structure</classLabel>
<deletedAxiom>&apos;multi cell part structure&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
<deletedAxiom>&apos;multi cell part structure&apos; SubClassOf &apos;anatomical cluster&apos;</deletedAxiom>
<newAxiom>&apos;multi cell part structure&apos; SubClassOf &apos;anatomical structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903539</classIRI>
<classLabel>protein localization to postsynaptic membrane</classLabel>
<deletedAxiom>&apos;protein localization to postsynaptic membrane&apos; SubClassOf &apos;protein localization to membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;protein localization to postsynaptic membrane&apos; SubClassOf &apos;protein localization to cell periphery&apos;</deletedAxiom>
<deletedAxiom>&apos;protein localization to postsynaptic membrane&apos; SubClassOf &apos;protein localization to postsynapse&apos;</deletedAxiom>
<deletedAxiom>&apos;protein localization to postsynaptic membrane&apos; EquivalentTo &apos;protein localization&apos; and (&apos;has target end location&apos; some &apos;postsynaptic membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;protein localization to postsynaptic membrane&apos; SubClassOf &apos;has target end location&apos; some &apos;postsynaptic membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903540</classIRI>
<classLabel>establishment of protein localization to postsynaptic membrane</classLabel>
<deletedAxiom>&apos;establishment of protein localization to postsynaptic membrane&apos; SubClassOf &apos;establishment of protein localization to membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;establishment of protein localization to postsynaptic membrane&apos; SubClassOf &apos;protein localization to postsynaptic membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;establishment of protein localization to postsynaptic membrane&apos; EquivalentTo &apos;establishment of protein localization&apos; and (&apos;has target end location&apos; some &apos;postsynaptic membrane&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070050</classIRI>
<classLabel>neuron cellular homeostasis</classLabel>
<deletedAxiom>&apos;neuron cellular homeostasis&apos; SubClassOf &apos;anatomical structure homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_72587</classIRI>
<newAxiom>http://purl.obolibrary.org/obo/CHEBI_72587 SubClassOf http://purl.obolibrary.org/obo/CHEBI_166902</newAxiom>
<newAxiom>http://purl.obolibrary.org/obo/CHEBI_72587 SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of some http://purl.obolibrary.org/obo/CHEBI_18357</newAxiom>
<newAxiom>http://purl.obolibrary.org/obo/CHEBI_72587 SubClassOf &apos;has role&apos; some &apos;human metabolite&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000304</classIRI>
<classLabel>tendon sheath</classLabel>
<deletedAxiom>&apos;tendon sheath&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001607</classIRI>
<classLabel>sphincter pupillae</classLabel>
<deletedAxiom>&apos;sphincter pupillae&apos; SubClassOf &apos;iris smooth muscle&apos;</deletedAxiom>
<newAxiom>&apos;sphincter pupillae&apos; SubClassOf &apos;iris smooth muscle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035725</classIRI>
<classLabel>sodium ion transmembrane transport</classLabel>
<newAxiom>&apos;sodium ion transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001608</classIRI>
<classLabel>dilatator pupillae</classLabel>
<deletedAxiom>&apos;dilatator pupillae&apos; SubClassOf &apos;iris smooth muscle&apos;</deletedAxiom>
<newAxiom>&apos;dilatator pupillae&apos; SubClassOf &apos;iris smooth muscle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090461</classIRI>
<classLabel>glutamate homeostasis</classLabel>
<deletedAxiom>&apos;glutamate homeostasis&apos; SubClassOf &apos;amino acid homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamate homeostasis&apos; SubClassOf &apos;anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamate homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;glutamate(1-)&apos;)</deletedAxiom>
<newAxiom>&apos;glutamate homeostasis&apos; SubClassOf &apos;cellular chemical homeostasis&apos;</newAxiom>
<newAxiom>&apos;glutamate homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;glutamate(1-)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000158</classIRI>
<classLabel>membranous layer</classLabel>
<deletedAxiom>&apos;membranous layer&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0014795</classIRI>
<classLabel>pelvic appendage muscle</classLabel>
<deletedAxiom>&apos;pelvic appendage muscle&apos; SubClassOf &apos;part of&apos; some &apos;pelvic appendage musculature&apos;</deletedAxiom>
<newAxiom>&apos;pelvic appendage muscle&apos; SubClassOf &apos;part of&apos; some &apos;pelvic appendage musculature&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0014794</classIRI>
<classLabel>pectoral appendage muscle</classLabel>
<deletedAxiom>&apos;pectoral appendage muscle&apos; SubClassOf &apos;part of&apos; some &apos;pectoral appendage musculature&apos;</deletedAxiom>
<newAxiom>&apos;pectoral appendage muscle&apos; SubClassOf &apos;part of&apos; some &apos;pectoral appendage musculature&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000167</classIRI>
<classLabel>oral cavity</classLabel>
<deletedAxiom>&apos;oral cavity&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0013411</classIRI>
<classLabel>cranial cavity</classLabel>
<deletedAxiom>&apos;cranial cavity&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008066</classIRI>
<classLabel>glutamate receptor activity</classLabel>
<deletedAxiom>&apos;glutamate receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some &apos;glutamate(1-)&apos;)</deletedAxiom>
<deletedAxiom>&apos;glutamate receptor activity&apos; SubClassOf &apos;transmembrane signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamate receptor activity&apos; SubClassOf &apos;has input&apos; some &apos;glutamate(1-)&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamate receptor activity&apos; SubClassOf &apos;has_part&apos; some &apos;glutamate binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001434</classIRI>
<classLabel>skeletal system</classLabel>
<deletedAxiom>&apos;skeletal system&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090494</classIRI>
<classLabel>dopamine uptake</classLabel>
<deletedAxiom>&apos;dopamine uptake&apos; EquivalentTo &apos;transport&apos; and (&apos;has target start location&apos; some &apos;extracellular region&apos;) and (&apos;has target end location&apos; some &apos;intracellular anatomical structure&apos;) and (&apos;has primary input&apos; some &apos;dopaminium(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;dopamine uptake&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine uptake&apos; SubClassOf &apos;dopamine transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007617</classIRI>
<classLabel>synovial cavity of joint</classLabel>
<deletedAxiom>&apos;synovial cavity of joint&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033045</classIRI>
<classLabel>regulation of sister chromatid segregation</classLabel>
<deletedAxiom>&apos;regulation of sister chromatid segregation&apos; SubClassOf &apos;regulation of cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033046</classIRI>
<classLabel>negative regulation of sister chromatid segregation</classLabel>
<deletedAxiom>&apos;negative regulation of sister chromatid segregation&apos; SubClassOf &apos;negative regulation of cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007616</classIRI>
<classLabel>layer of synovial tissue</classLabel>
<deletedAxiom>&apos;layer of synovial tissue&apos; SubClassOf &apos;composed primarily of&apos; some &apos;connective tissue&apos;</deletedAxiom>
<deletedAxiom>&apos;layer of synovial tissue&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
<newAxiom>&apos;layer of synovial tissue&apos; SubClassOf &apos;composed primarily of&apos; some &apos;connective tissue&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008947</classIRI>
<classLabel>respiratory primordium</classLabel>
<deletedAxiom>&apos;respiratory primordium&apos; SubClassOf &apos;primordium&apos;</deletedAxiom>
<newAxiom>&apos;respiratory primordium&apos; SubClassOf &apos;primordium&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016500</classIRI>
<classLabel>protein-hormone receptor activity</classLabel>
<deletedAxiom>&apos;protein-hormone receptor activity&apos; SubClassOf &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000170</classIRI>
<classLabel>pair of lungs</classLabel>
<deletedAxiom>&apos;pair of lungs&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000178</classIRI>
<classLabel>blood</classLabel>
<deletedAxiom>&apos;blood&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903768</classIRI>
<classLabel>taste receptor complex</classLabel>
<deletedAxiom>&apos;taste receptor complex&apos; SubClassOf &apos;capable of&apos; some &apos;taste receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;taste receptor complex&apos; SubClassOf &apos;receptor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;taste receptor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;taste receptor activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005899</classIRI>
<classLabel>insulin receptor complex</classLabel>
<deletedAxiom>&apos;insulin receptor complex&apos; SubClassOf &apos;only in taxon&apos; some &apos;Eumetazoa&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor complex&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor complex&apos; SubClassOf &apos;plasma membrane signaling receptor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;insulin receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;insulin receptor complex&apos; SubClassOf &apos;capable of&apos; some &apos;insulin receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor complex&apos; SubClassOf &apos;protein kinase complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015103</classIRI>
<classLabel>inorganic anion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;inorganic anion transmembrane transporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015101</classIRI>
<classLabel>organic cation transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;organic cation transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;organic cation transmembrane transporter activity&apos; SubClassOf &apos;transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_35522</classIRI>
<classLabel>beta-adrenergic agonist</classLabel>
<deletedAxiom>&apos;beta-adrenergic agonist&apos; SubClassOf &apos;beta-adrenergic drug&apos;</deletedAxiom>
<deletedAxiom>&apos;beta-adrenergic agonist&apos; SubClassOf &apos;adrenergic agonist&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000016</classIRI>
<classLabel>endocrine pancreas</classLabel>
<deletedAxiom>&apos;endocrine pancreas&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000023</classIRI>
<classLabel>wing</classLabel>
<deletedAxiom>&apos;wing&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000030</classIRI>
<classLabel>lamina propria</classLabel>
<deletedAxiom>&apos;lamina propria&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000045</classIRI>
<classLabel>ganglion</classLabel>
<deletedAxiom>&apos;ganglion&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034220</classIRI>
<classLabel>ion transmembrane transport</classLabel>
<deletedAxiom>&apos;ion transmembrane transport&apos; EquivalentTo &apos;transport&apos; and (&apos;results in transport across&apos; some &apos;membrane&apos;) and (&apos;has primary input&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;ion transmembrane transport&apos; EquivalentTo &apos;transport&apos; and (&apos;results in transport across&apos; some &apos;membrane&apos;) and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000006</classIRI>
<classLabel>islet of Langerhans</classLabel>
<deletedAxiom>&apos;islet of Langerhans&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048872</classIRI>
<classLabel>homeostasis of number of cells</classLabel>
<deletedAxiom>&apos;homeostasis of number of cells&apos; SubClassOf &apos;homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;homeostasis of number of cells&apos; SubClassOf &apos;multicellular organismal homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048875</classIRI>
<classLabel>chemical homeostasis within a tissue</classLabel>
<deletedAxiom>&apos;chemical homeostasis within a tissue&apos; SubClassOf &apos;chemical homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;chemical homeostasis within a tissue&apos; SubClassOf &apos;tissue homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000009</classIRI>
<classLabel>submucosa</classLabel>
<deletedAxiom>&apos;submucosa&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0012082</classIRI>
<classLabel>bronchial lumen</classLabel>
<deletedAxiom>&apos;bronchial lumen&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008814</classIRI>
<classLabel>pharyngeal arch system</classLabel>
<deletedAxiom>&apos;pharyngeal arch system&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_4200230</classIRI>
<classLabel>surface of bone</classLabel>
<deletedAxiom>&apos;surface of bone&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072501</classIRI>
<classLabel>cellular divalent inorganic anion homeostasis</classLabel>
<deletedAxiom>&apos;cellular divalent inorganic anion homeostasis&apos; SubClassOf &apos;divalent inorganic anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular divalent inorganic anion homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular divalent inorganic anion homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;divalent inorganic anion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072502</classIRI>
<classLabel>cellular trivalent inorganic anion homeostasis</classLabel>
<deletedAxiom>&apos;cellular trivalent inorganic anion homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular trivalent inorganic anion homeostasis&apos; SubClassOf &apos;trivalent inorganic anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular trivalent inorganic anion homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;trivalent inorganic anion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072505</classIRI>
<classLabel>divalent inorganic anion homeostasis</classLabel>
<deletedAxiom>&apos;divalent inorganic anion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;divalent inorganic anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;divalent inorganic anion homeostasis&apos; SubClassOf &apos;anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;divalent inorganic anion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;divalent inorganic anion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;divalent inorganic anion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072506</classIRI>
<classLabel>trivalent inorganic anion homeostasis</classLabel>
<deletedAxiom>&apos;trivalent inorganic anion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;trivalent inorganic anion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;trivalent inorganic anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;trivalent inorganic anion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;trivalent inorganic anion&apos;</deletedAxiom>
<deletedAxiom>&apos;trivalent inorganic anion homeostasis&apos; SubClassOf &apos;anion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000062</classIRI>
<classLabel>organ</classLabel>
<deletedAxiom>&apos;organ&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000061</classIRI>
<classLabel>anatomical structure</classLabel>
<deletedAxiom>&apos;anatomical structure&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000075</classIRI>
<classLabel>subdivision of skeletal system</classLabel>
<deletedAxiom>&apos;subdivision of skeletal system&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0012054</classIRI>
<classLabel>myocoele</classLabel>
<deletedAxiom>&apos;myocoele&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000086</classIRI>
<classLabel>zona pellucida</classLabel>
<deletedAxiom>&apos;zona pellucida&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903792</classIRI>
<classLabel>negative regulation of anion transport</classLabel>
<deletedAxiom>&apos;negative regulation of anion transport&apos; SubClassOf &apos;negatively regulates&apos; some &apos;anion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of anion transport&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;anion transport&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of anion transport&apos; SubClassOf &apos;negative regulation of ion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of anion transport&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903793</classIRI>
<classLabel>positive regulation of anion transport</classLabel>
<deletedAxiom>&apos;positive regulation of anion transport&apos; SubClassOf &apos;positive regulation of ion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of anion transport&apos; SubClassOf &apos;positively regulates&apos; some &apos;anion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of anion transport&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of anion transport&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;anion transport&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903796</classIRI>
<classLabel>negative regulation of inorganic anion transmembrane transport</classLabel>
<deletedAxiom>&apos;negative regulation of inorganic anion transmembrane transport&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of inorganic anion transmembrane transport&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903795</classIRI>
<classLabel>regulation of inorganic anion transmembrane transport</classLabel>
<deletedAxiom>&apos;regulation of inorganic anion transmembrane transport&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of inorganic anion transmembrane transport&apos; SubClassOf &apos;regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903797</classIRI>
<classLabel>positive regulation of inorganic anion transmembrane transport</classLabel>
<deletedAxiom>&apos;positive regulation of inorganic anion transmembrane transport&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of inorganic anion transmembrane transport&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030642</classIRI>
<classLabel>cellular sulfate ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular sulfate ion homeostasis&apos; SubClassOf &apos;cellular divalent inorganic anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;cellular sulfate ion homeostasis&apos; SubClassOf &apos;cellular chemical homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030643</classIRI>
<classLabel>cellular phosphate ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular phosphate ion homeostasis&apos; SubClassOf &apos;cellular trivalent inorganic anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;cellular phosphate ion homeostasis&apos; SubClassOf &apos;cellular chemical homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008886</classIRI>
<classLabel>pulmonary vascular system</classLabel>
<deletedAxiom>&apos;pulmonary vascular system&apos; SubClassOf &apos;vascular system&apos;</deletedAxiom>
<newAxiom>&apos;pulmonary vascular system&apos; SubClassOf &apos;vascular system&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0014704</classIRI>
<classLabel>pleuroperitoneal canal lumen</classLabel>
<deletedAxiom>&apos;pleuroperitoneal canal lumen&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015075</classIRI>
<classLabel>ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ion transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;ion&apos;)</deletedAxiom>
<deletedAxiom>&apos;ion transmembrane transporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;ion&apos;</deletedAxiom>
<newAxiom>&apos;ion transmembrane transporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;monoatomic ion&apos;</newAxiom>
<newAxiom>&apos;ion transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0018260</classIRI>
<classLabel>layer of muscle tissue</classLabel>
<deletedAxiom>&apos;layer of muscle tissue&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0018254</classIRI>
<classLabel>skeletal musculature</classLabel>
<deletedAxiom>&apos;skeletal musculature&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003891</classIRI>
<classLabel>stroma</classLabel>
<deletedAxiom>&apos;stroma&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002561</classIRI>
<classLabel>lumen of central nervous system</classLabel>
<deletedAxiom>&apos;lumen of central nervous system&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035433</classIRI>
<classLabel>acetate transmembrane transport</classLabel>
<deletedAxiom>&apos;acetate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;acetate transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003842</classIRI>
<classLabel>neural tube lumen</classLabel>
<deletedAxiom>&apos;neural tube lumen&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002521</classIRI>
<classLabel>elastic tissue</classLabel>
<deletedAxiom>&apos;elastic tissue&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002522</classIRI>
<classLabel>tunica media</classLabel>
<deletedAxiom>&apos;tunica media&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001215</classIRI>
<classLabel>inferior mesenteric vein</classLabel>
<deletedAxiom>&apos;inferior mesenteric vein&apos; SubClassOf &apos;tributary of&apos; some &apos;splenic vein&apos;</deletedAxiom>
<newAxiom>&apos;inferior mesenteric vein&apos; SubClassOf &apos;tributary of&apos; some &apos;splenic vein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PR_000030035</classIRI>
<classLabel>G-protein coupled receptor</classLabel>
<deletedAxiom>&apos;G-protein coupled receptor&apos; SubClassOf &apos;protein&apos;</deletedAxiom>
<deletedAxiom>&apos;G-protein coupled receptor&apos; EquivalentTo &apos;protein&apos; and (&apos;capable of&apos; some &apos;G protein-coupled receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;G-protein coupled receptor&apos; SubClassOf &apos;capable of&apos; some &apos;G protein-coupled receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903959</classIRI>
<classLabel>regulation of anion transmembrane transport</classLabel>
<deletedAxiom>&apos;regulation of anion transmembrane transport&apos; SubClassOf &apos;regulates&apos; some &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of anion transmembrane transport&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;anion transmembrane transport&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of anion transmembrane transport&apos; SubClassOf &apos;regulation of ion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of anion transmembrane transport&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903961</classIRI>
<classLabel>positive regulation of anion transmembrane transport</classLabel>
<deletedAxiom>&apos;positive regulation of anion transmembrane transport&apos; SubClassOf &apos;positively regulates&apos; some &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of anion transmembrane transport&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;anion transmembrane transport&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of anion transmembrane transport&apos; SubClassOf &apos;positive regulation of ion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of anion transmembrane transport&apos; SubClassOf &apos;positive regulation of anion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of anion transmembrane transport&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903960</classIRI>
<classLabel>negative regulation of anion transmembrane transport</classLabel>
<deletedAxiom>&apos;negative regulation of anion transmembrane transport&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;anion transmembrane transport&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of anion transmembrane transport&apos; SubClassOf &apos;negative regulation of ion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of anion transmembrane transport&apos; SubClassOf &apos;negatively regulates&apos; some &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of anion transmembrane transport&apos; SubClassOf &apos;negative regulation of anion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of anion transmembrane transport&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001282</classIRI>
<classLabel>intralobular bile duct</classLabel>
<deletedAxiom>&apos;intralobular bile duct&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006873</classIRI>
<classLabel>cellular ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular ion homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;cellular ion homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monoatomic ion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006883</classIRI>
<classLabel>cellular sodium ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular sodium ion homeostasis&apos; SubClassOf &apos;cellular monovalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006885</classIRI>
<classLabel>regulation of pH</classLabel>
<deletedAxiom>&apos;regulation of pH&apos; SubClassOf &apos;monovalent inorganic cation homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of pH&apos; SubClassOf &apos;cation homeostasis&apos;</newAxiom>
<newAxiom>&apos;regulation of pH&apos; SubClassOf &apos;biological regulation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007475</classIRI>
<classLabel>matrix-based tissue</classLabel>
<deletedAxiom>&apos;matrix-based tissue&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007473</classIRI>
<classLabel>lumen of epithelial sac</classLabel>
<deletedAxiom>&apos;lumen of epithelial sac&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098962</classIRI>
<classLabel>regulation of postsynaptic neurotransmitter receptor activity</classLabel>
<deletedAxiom>&apos;regulation of postsynaptic neurotransmitter receptor activity&apos; EquivalentTo &apos;regulation of molecular function&apos; and (&apos;regulates&apos; some &apos;postsynaptic neurotransmitter receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of postsynaptic neurotransmitter receptor activity&apos; SubClassOf &apos;regulates&apos; some &apos;postsynaptic neurotransmitter receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of postsynaptic neurotransmitter receptor activity&apos; SubClassOf &apos;regulation of nervous system process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of postsynaptic neurotransmitter receptor activity&apos; SubClassOf &apos;modulation of chemical synaptic transmission&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of postsynaptic neurotransmitter receptor activity&apos; SubClassOf &apos;regulation of neurotransmitter receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098967</classIRI>
<classLabel>exocytic insertion of neurotransmitter receptor to postsynaptic membrane</classLabel>
<deletedAxiom>&apos;exocytic insertion of neurotransmitter receptor to postsynaptic membrane&apos; SubClassOf &apos;part of&apos; some &apos;neurotransmitter receptor transport to postsynaptic membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;exocytic insertion of neurotransmitter receptor to postsynaptic membrane&apos; EquivalentTo &apos;exocytosis&apos; and (&apos;part of&apos; some &apos;neurotransmitter receptor transport to postsynaptic membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;exocytic insertion of neurotransmitter receptor to postsynaptic membrane&apos; SubClassOf &apos;regulation of postsynaptic membrane neurotransmitter receptor levels&apos;</deletedAxiom>
<deletedAxiom>&apos;exocytic insertion of neurotransmitter receptor to postsynaptic membrane&apos; SubClassOf &apos;exocytosis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098969</classIRI>
<classLabel>neurotransmitter receptor transport to postsynaptic membrane</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor transport to postsynaptic membrane&apos; SubClassOf &apos;establishment of protein localization to postsynaptic membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor transport to postsynaptic membrane&apos; SubClassOf &apos;receptor localization to synapse&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor transport to postsynaptic membrane&apos; SubClassOf &apos;neurotransmitter receptor transport to plasma membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor transport to postsynaptic membrane&apos; EquivalentTo &apos;protein transport&apos; and (&apos;has target end location&apos; some &apos;postsynaptic membrane&apos;) and (&apos;has primary input&apos; some &apos;neurotransmitter receptor complex&apos;)</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor transport to postsynaptic membrane&apos; SubClassOf &apos;regulation of postsynaptic membrane neurotransmitter receptor levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098971</classIRI>
<classLabel>anterograde dendritic transport of neurotransmitter receptor complex</classLabel>
<deletedAxiom>&apos;anterograde dendritic transport of neurotransmitter receptor complex&apos; SubClassOf &apos;anterograde dendritic transport&apos;</deletedAxiom>
<deletedAxiom>&apos;anterograde dendritic transport of neurotransmitter receptor complex&apos; EquivalentTo &apos;transport&apos; and (&apos;occurs in&apos; some &apos;dendrite cytoplasm&apos;) and (&apos;has target end location&apos; some &apos;postsynapse&apos;) and (&apos;results in transport along&apos; some &apos;microtubule&apos;) and (&apos;has primary input&apos; some &apos;neurotransmitter receptor complex&apos;)</deletedAxiom>
<deletedAxiom>&apos;anterograde dendritic transport of neurotransmitter receptor complex&apos; SubClassOf &apos;has primary input&apos; some &apos;neurotransmitter receptor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;anterograde dendritic transport of neurotransmitter receptor complex&apos; SubClassOf &apos;receptor localization to synapse&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098988</classIRI>
<classLabel>G protein-coupled glutamate receptor activity</classLabel>
<deletedAxiom>&apos;G protein-coupled glutamate receptor activity&apos; SubClassOf &apos;G protein-coupled receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled glutamate receptor activity&apos; EquivalentTo &apos;G protein-coupled receptor activity&apos; and (&apos;has input&apos; some &apos;glutamate(1-)&apos;)</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled glutamate receptor activity&apos; SubClassOf &apos;glutamate receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030545</classIRI>
<classLabel>signaling receptor regulator activity</classLabel>
<deletedAxiom>&apos;signaling receptor regulator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;regulates&apos; some &apos;signaling receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;signaling receptor regulator activity&apos; SubClassOf &apos;molecular function regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;signaling receptor regulator activity&apos; SubClassOf &apos;regulates&apos; some &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030546</classIRI>
<classLabel>signaling receptor activator activity</classLabel>
<deletedAxiom>&apos;signaling receptor activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;signaling receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;signaling receptor activator activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;signaling receptor activator activity&apos; SubClassOf &apos;molecular function activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;signaling receptor activator activity&apos; SubClassOf &apos;signaling receptor regulator activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030547</classIRI>
<classLabel>signaling receptor inhibitor activity</classLabel>
<deletedAxiom>&apos;signaling receptor inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;negatively regulates&apos; some &apos;signaling receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;signaling receptor inhibitor activity&apos; SubClassOf &apos;part of&apos; some &apos;negative regulation of signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;signaling receptor inhibitor activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;signaling receptor inhibitor activity&apos; SubClassOf &apos;signaling receptor regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;signaling receptor inhibitor activity&apos; SubClassOf &apos;molecular function inhibitor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030548</classIRI>
<classLabel>acetylcholine receptor regulator activity</classLabel>
<deletedAxiom>&apos;acetylcholine receptor regulator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;regulates&apos; some &apos;acetylcholine receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor regulator activity&apos; SubClassOf &apos;neurotransmitter receptor regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor regulator activity&apos; SubClassOf &apos;regulates&apos; some &apos;acetylcholine receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030549</classIRI>
<classLabel>acetylcholine receptor activator activity</classLabel>
<deletedAxiom>&apos;acetylcholine receptor activator activity&apos; SubClassOf &apos;acetylcholine receptor regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor activator activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;acetylcholine receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor activator activity&apos; SubClassOf &apos;signaling receptor activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;acetylcholine receptor activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030550</classIRI>
<classLabel>acetylcholine receptor inhibitor activity</classLabel>
<deletedAxiom>&apos;acetylcholine receptor inhibitor activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;acetylcholine receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor inhibitor activity&apos; SubClassOf &apos;signaling receptor inhibitor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor inhibitor activity&apos; SubClassOf &apos;acetylcholine receptor regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;negatively regulates&apos; some &apos;acetylcholine receptor activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030573</classIRI>
<classLabel>bile acid catabolic process</classLabel>
<deletedAxiom>&apos;bile acid catabolic process&apos; SubClassOf &apos;catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;bile acid catabolic process&apos; SubClassOf &apos;monocarboxylic acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002616</classIRI>
<classLabel>regional part of brain</classLabel>
<deletedAxiom>&apos;regional part of brain&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030594</classIRI>
<classLabel>neurotransmitter receptor activity</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor activity&apos; SubClassOf &apos;signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor activity&apos; SubClassOf &apos;has_part&apos; some &apos;neurotransmitter binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042592</classIRI>
<classLabel>homeostatic process</classLabel>
<deletedAxiom>&apos;homeostatic process&apos; SubClassOf &apos;regulation of biological quality&apos;</deletedAxiom>
<newAxiom>&apos;homeostatic process&apos; SubClassOf &apos;biological_process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003902</classIRI>
<classLabel>retinal neural layer</classLabel>
<newAxiom>&apos;retinal neural layer&apos; SubClassOf &apos;ectoderm-derived structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050900</classIRI>
<classLabel>leukocyte migration</classLabel>
<newAxiom>&apos;leukocyte migration&apos; SubClassOf &apos;only in taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;leukocyte migration&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001941</classIRI>
<classLabel>postsynaptic membrane organization</classLabel>
<deletedAxiom>&apos;postsynaptic membrane organization&apos; SubClassOf &apos;results in organization of&apos; some &apos;postsynaptic membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic membrane organization&apos; SubClassOf &apos;membrane organization&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic membrane organization&apos; SubClassOf &apos;part of&apos; some &apos;postsynapse organization&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic membrane organization&apos; EquivalentTo &apos;cellular component organization&apos; and (&apos;results in organization of&apos; some &apos;postsynaptic membrane&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001933</classIRI>
<classLabel>negative regulation of protein phosphorylation</classLabel>
<deletedAxiom>&apos;negative regulation of protein phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;protein phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein phosphorylation&apos; SubClassOf &apos;regulation of protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein phosphorylation&apos; SubClassOf &apos;negative regulation of phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein phosphorylation&apos; SubClassOf &apos;negative regulation of protein modification process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein phosphorylation&apos; SubClassOf &apos;negatively regulates&apos; some &apos;protein phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001934</classIRI>
<classLabel>positive regulation of protein phosphorylation</classLabel>
<deletedAxiom>&apos;positive regulation of protein phosphorylation&apos; SubClassOf &apos;positively regulates&apos; some &apos;protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;protein phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein phosphorylation&apos; SubClassOf &apos;positive regulation of protein modification process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein phosphorylation&apos; SubClassOf &apos;regulation of protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein phosphorylation&apos; SubClassOf &apos;positive regulation of phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001932</classIRI>
<classLabel>regulation of protein phosphorylation</classLabel>
<deletedAxiom>&apos;regulation of protein phosphorylation&apos; SubClassOf &apos;regulation of protein modification process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein phosphorylation&apos; SubClassOf &apos;regulates&apos; some &apos;protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;protein phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of protein phosphorylation&apos; SubClassOf &apos;regulation of phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902706</classIRI>
<classLabel>hexose catabolic process to acetate</classLabel>
<deletedAxiom>&apos;hexose catabolic process to acetate&apos; SubClassOf &apos;acetate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to acetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some &apos;acetate&apos;) and (&apos;has primary input&apos; some &apos;hexose&apos;)</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to acetate&apos; SubClassOf &apos;hexose catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to acetate&apos; SubClassOf &apos;has primary output&apos; some &apos;acetate&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004220</classIRI>
<classLabel>large intestine smooth muscle</classLabel>
<deletedAxiom>&apos;large intestine smooth muscle&apos; SubClassOf &apos;overlaps&apos; some &apos;muscle layer of large intestine&apos;</deletedAxiom>
<newAxiom>&apos;large intestine smooth muscle&apos; SubClassOf &apos;overlaps&apos; some &apos;muscle layer of large intestine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004221</classIRI>
<classLabel>intestine smooth muscle</classLabel>
<deletedAxiom>&apos;intestine smooth muscle&apos; SubClassOf &apos;overlaps&apos; some &apos;muscle layer of intestine&apos;</deletedAxiom>
<newAxiom>&apos;intestine smooth muscle&apos; SubClassOf &apos;overlaps&apos; some &apos;muscle layer of intestine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004239</classIRI>
<classLabel>small intestine smooth muscle</classLabel>
<deletedAxiom>&apos;small intestine smooth muscle&apos; SubClassOf &apos;overlaps&apos; some &apos;muscle layer of small intestine&apos;</deletedAxiom>
<newAxiom>&apos;small intestine smooth muscle&apos; SubClassOf &apos;overlaps&apos; some &apos;muscle layer of small intestine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006812</classIRI>
<classLabel>cation transport</classLabel>
<deletedAxiom>&apos;cation transport&apos; SubClassOf &apos;has primary input&apos; some &apos;cation&apos;</deletedAxiom>
<deletedAxiom>&apos;cation transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has primary input&apos; some &apos;cation&apos;)</deletedAxiom>
<newAxiom>&apos;cation transport&apos; SubClassOf &apos;has primary input&apos; some &apos;monoatomic cation&apos;</newAxiom>
<newAxiom>&apos;cation transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006811</classIRI>
<classLabel>ion transport</classLabel>
<deletedAxiom>&apos;ion transport&apos; SubClassOf &apos;has primary input&apos; some &apos;ion&apos;</deletedAxiom>
<deletedAxiom>&apos;ion transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has primary input&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;ion transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
<newAxiom>&apos;ion transport&apos; SubClassOf &apos;has primary input&apos; some &apos;monoatomic ion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005564</classIRI>
<classLabel>gonad primordium</classLabel>
<deletedAxiom>&apos;gonad primordium&apos; SubClassOf &apos;primordium&apos;</deletedAxiom>
<newAxiom>&apos;gonad primordium&apos; SubClassOf &apos;primordium&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006820</classIRI>
<classLabel>anion transport</classLabel>
<deletedAxiom>&apos;anion transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has primary input&apos; some &apos;anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;anion transport&apos; SubClassOf &apos;has primary input&apos; some &apos;anion&apos;</deletedAxiom>
<deletedAxiom>&apos;anion transport&apos; SubClassOf &apos;ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098960</classIRI>
<classLabel>postsynaptic neurotransmitter receptor activity</classLabel>
<deletedAxiom>&apos;postsynaptic neurotransmitter receptor activity&apos; EquivalentTo &apos;neurotransmitter receptor activity&apos; and (&apos;part of&apos; some &apos;chemical synaptic transmission&apos;)</deletedAxiom>
<deletedAxiom>&apos;postsynaptic neurotransmitter receptor activity&apos; SubClassOf &apos;neurotransmitter receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic neurotransmitter receptor activity&apos; SubClassOf &apos;part of&apos; some &apos;chemical synaptic transmission, postsynaptic&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic neurotransmitter receptor activity&apos; SubClassOf &apos;occurs in&apos; some &apos;postsynaptic membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006833</classIRI>
<classLabel>lumen of trachea</classLabel>
<deletedAxiom>&apos;lumen of trachea&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006837</classIRI>
<classLabel>serotonin transport</classLabel>
<deletedAxiom>&apos;serotonin transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006846</classIRI>
<classLabel>surface groove</classLabel>
<deletedAxiom>&apos;surface groove&apos; SubClassOf &apos;surface structure&apos;</deletedAxiom>
<deletedAxiom>&apos;surface groove&apos; EquivalentTo &apos;surface structure&apos; and (&apos;has quality&apos; some &apos;grooved&apos;)</deletedAxiom>
<newAxiom>&apos;surface groove&apos; SubClassOf &apos;immaterial anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000273</classIRI>
<classLabel>positive regulation of signaling receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of signaling receptor activity&apos; SubClassOf &apos;positive regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signaling receptor activity&apos; SubClassOf &apos;regulation of signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signaling receptor activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;signaling receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signaling receptor activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000272</classIRI>
<classLabel>negative regulation of signaling receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of signaling receptor activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signaling receptor activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;signaling receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signaling receptor activity&apos; SubClassOf &apos;negative regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signaling receptor activity&apos; SubClassOf &apos;regulation of signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902683</classIRI>
<classLabel>regulation of receptor localization to synapse</classLabel>
<deletedAxiom>&apos;regulation of receptor localization to synapse&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;receptor localization to synapse&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of receptor localization to synapse&apos; SubClassOf &apos;regulates&apos; some &apos;receptor localization to synapse&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of receptor localization to synapse&apos; SubClassOf &apos;regulation of localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902685</classIRI>
<classLabel>positive regulation of receptor localization to synapse</classLabel>
<deletedAxiom>&apos;positive regulation of receptor localization to synapse&apos; SubClassOf &apos;regulation of receptor localization to synapse&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of receptor localization to synapse&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of receptor localization to synapse&apos; SubClassOf &apos;positively regulates&apos; some &apos;receptor localization to synapse&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of receptor localization to synapse&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;receptor localization to synapse&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902684</classIRI>
<classLabel>negative regulation of receptor localization to synapse</classLabel>
<deletedAxiom>&apos;negative regulation of receptor localization to synapse&apos; SubClassOf &apos;negatively regulates&apos; some &apos;receptor localization to synapse&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of receptor localization to synapse&apos; SubClassOf &apos;regulation of receptor localization to synapse&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of receptor localization to synapse&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;receptor localization to synapse&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of receptor localization to synapse&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060249</classIRI>
<classLabel>anatomical structure homeostasis</classLabel>
<deletedAxiom>&apos;anatomical structure homeostasis&apos; SubClassOf &apos;homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;anatomical structure homeostasis&apos; SubClassOf &apos;multicellular organismal homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042421</classIRI>
<classLabel>norepinephrine biosynthetic process</classLabel>
<deletedAxiom>&apos;norepinephrine biosynthetic process&apos; SubClassOf &apos;biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;norepinephrine biosynthetic process&apos; SubClassOf &apos;organic substance biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042420</classIRI>
<classLabel>dopamine catabolic process</classLabel>
<deletedAxiom>&apos;dopamine catabolic process&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary input&apos; some &apos;dopaminium(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;dopamine catabolic process&apos; SubClassOf &apos;dopamine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine catabolic process&apos; SubClassOf &apos;catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine catabolic process&apos; SubClassOf &apos;has primary input&apos; some &apos;dopaminium(1+)&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042417</classIRI>
<classLabel>dopamine metabolic process</classLabel>
<deletedAxiom>&apos;dopamine metabolic process&apos; SubClassOf &apos;nitrogen compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some &apos;dopaminium(1+)&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some &apos;dopaminium(1+)&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042416</classIRI>
<classLabel>dopamine biosynthetic process</classLabel>
<deletedAxiom>&apos;dopamine biosynthetic process&apos; SubClassOf &apos;has primary output&apos; some &apos;dopaminium(1+)&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine biosynthetic process&apos; SubClassOf &apos;biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine biosynthetic process&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some &apos;dopaminium(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;dopamine biosynthetic process&apos; SubClassOf &apos;dopamine metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042415</classIRI>
<classLabel>norepinephrine metabolic process</classLabel>
<deletedAxiom>&apos;norepinephrine metabolic process&apos; SubClassOf &apos;metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;norepinephrine metabolic process&apos; SubClassOf &apos;organic substance metabolic process&apos;</newAxiom>
<newAxiom>&apos;norepinephrine metabolic process&apos; SubClassOf &apos;nitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098877</classIRI>
<classLabel>neurotransmitter receptor transport to plasma membrane</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor transport to plasma membrane&apos; SubClassOf &apos;neurotransmitter receptor transport&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor transport to plasma membrane&apos; SubClassOf &apos;protein localization to cell periphery&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor transport to plasma membrane&apos; EquivalentTo &apos;protein transport&apos; and (&apos;has target end location&apos; some &apos;plasma membrane&apos;) and (&apos;has primary input&apos; some &apos;neurotransmitter receptor complex&apos;)</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor transport to plasma membrane&apos; SubClassOf &apos;establishment of protein localization to membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor transport to plasma membrane&apos; SubClassOf &apos;vesicle-mediated transport to the plasma membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098878</classIRI>
<classLabel>neurotransmitter receptor complex</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor complex&apos; SubClassOf &apos;plasma membrane signaling receptor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;neurotransmitter receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor complex&apos; SubClassOf &apos;capable of&apos; some &apos;neurotransmitter receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004288</classIRI>
<classLabel>skeleton</classLabel>
<deletedAxiom>&apos;skeleton&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042422</classIRI>
<classLabel>norepinephrine catabolic process</classLabel>
<deletedAxiom>&apos;norepinephrine catabolic process&apos; SubClassOf &apos;catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;norepinephrine catabolic process&apos; SubClassOf &apos;organic substance catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0011234</classIRI>
<classLabel>fibrous membrane of synovial tendon sheath</classLabel>
<deletedAxiom>&apos;fibrous membrane of synovial tendon sheath&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050801</classIRI>
<classLabel>ion homeostasis</classLabel>
<deletedAxiom>&apos;ion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;ion&apos;</deletedAxiom>
<deletedAxiom>&apos;ion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;ion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monoatomic ion&apos;)</newAxiom>
<newAxiom>&apos;ion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;monoatomic ion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050803</classIRI>
<classLabel>regulation of synapse structure or activity</classLabel>
<newAxiom>&apos;regulation of synapse structure or activity&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;regulation of synapse structure or activity&apos; SubClassOf &apos;only in taxon&apos; some &apos;Eumetazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050865</classIRI>
<classLabel>regulation of cell activation</classLabel>
<newAxiom>&apos;regulation of cell activation&apos; SubClassOf &apos;regulation of multicellular organismal process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050866</classIRI>
<classLabel>negative regulation of cell activation</classLabel>
<newAxiom>&apos;negative regulation of cell activation&apos; SubClassOf &apos;negative regulation of multicellular organismal process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098802</classIRI>
<classLabel>plasma membrane signaling receptor complex</classLabel>
<deletedAxiom>&apos;plasma membrane signaling receptor complex&apos; SubClassOf &apos;receptor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;plasma membrane signaling receptor complex&apos; SubClassOf &apos;plasma membrane protein complex&apos;</deletedAxiom>
<deletedAxiom>&apos;plasma membrane signaling receptor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;part of&apos; some &apos;plasma membrane&apos;) and (&apos;capable of&apos; some &apos;signaling receptor activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050867</classIRI>
<classLabel>positive regulation of cell activation</classLabel>
<newAxiom>&apos;positive regulation of cell activation&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005427</classIRI>
<classLabel>corneal primordium</classLabel>
<deletedAxiom>&apos;corneal primordium&apos; SubClassOf &apos;primordium&apos;</deletedAxiom>
<newAxiom>&apos;corneal primordium&apos; SubClassOf &apos;primordium&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005423</classIRI>
<classLabel>developing anatomical structure</classLabel>
<deletedAxiom>&apos;developing anatomical structure&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098813</classIRI>
<classLabel>nuclear chromosome segregation</classLabel>
<deletedAxiom>&apos;nuclear chromosome segregation&apos; SubClassOf &apos;cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035240</classIRI>
<classLabel>dopamine binding</classLabel>
<deletedAxiom>&apos;dopamine binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;dopaminium(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;dopamine binding&apos; SubClassOf &apos;cation binding&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine binding&apos; SubClassOf &apos;has input&apos; some &apos;dopaminium(1+)&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098771</classIRI>
<classLabel>inorganic ion homeostasis</classLabel>
<deletedAxiom>&apos;inorganic ion homeostasis&apos; SubClassOf &apos;ion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;inorganic ion homeostasis&apos; SubClassOf &apos;chemical homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030320</classIRI>
<classLabel>cellular monovalent inorganic anion homeostasis</classLabel>
<deletedAxiom>&apos;cellular monovalent inorganic anion homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular monovalent inorganic anion homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monovalent inorganic anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;cellular monovalent inorganic anion homeostasis&apos; SubClassOf &apos;monovalent inorganic anion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001981</classIRI>
<classLabel>blood vessel</classLabel>
<deletedAxiom>&apos;blood vessel&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0065008</classIRI>
<classLabel>regulation of biological quality</classLabel>
<deletedAxiom>&apos;regulation of biological quality&apos; SubClassOf &apos;biological regulation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001873</classIRI>
<classLabel>polysaccharide immune receptor activity</classLabel>
<deletedAxiom>&apos;polysaccharide immune receptor activity&apos; SubClassOf &apos;has input&apos; some &apos;polysaccharide&apos;</deletedAxiom>
<deletedAxiom>&apos;polysaccharide immune receptor activity&apos; SubClassOf &apos;has_part&apos; some &apos;polysaccharide binding&apos;</deletedAxiom>
<deletedAxiom>&apos;polysaccharide immune receptor activity&apos; SubClassOf &apos;pattern recognition receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;polysaccharide immune receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some &apos;polysaccharide&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030292</classIRI>
<classLabel>protein tyrosine kinase inhibitor activity</classLabel>
<deletedAxiom>&apos;protein tyrosine kinase inhibitor activity&apos; SubClassOf &apos;part of&apos; some &apos;negative regulation of protein tyrosine kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein tyrosine kinase inhibitor activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;protein tyrosine kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein tyrosine kinase inhibitor activity&apos; SubClassOf &apos;protein kinase inhibitor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein tyrosine kinase inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;negatively regulates&apos; some &apos;protein tyrosine kinase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030293</classIRI>
<classLabel>transmembrane receptor protein tyrosine kinase inhibitor activity</classLabel>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase inhibitor activity&apos; SubClassOf &apos;protein tyrosine kinase inhibitor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase inhibitor activity&apos; SubClassOf &apos;signaling receptor inhibitor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase inhibitor activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;transmembrane receptor protein tyrosine kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;negatively regulates&apos; some &apos;transmembrane receptor protein tyrosine kinase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030295</classIRI>
<classLabel>protein kinase activator activity</classLabel>
<deletedAxiom>&apos;protein kinase activator activity&apos; SubClassOf &apos;kinase activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein kinase activator activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein kinase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;protein kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;protein kinase activator activity&apos; SubClassOf &apos;protein kinase regulator activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030296</classIRI>
<classLabel>protein tyrosine kinase activator activity</classLabel>
<deletedAxiom>&apos;protein tyrosine kinase activator activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;protein tyrosine kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein tyrosine kinase activator activity&apos; SubClassOf &apos;protein kinase activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein tyrosine kinase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;protein tyrosine kinase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030297</classIRI>
<classLabel>transmembrane receptor protein tyrosine kinase activator activity</classLabel>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase activator activity&apos; SubClassOf &apos;signaling receptor activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;transmembrane receptor protein tyrosine kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase activator activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;transmembrane receptor protein tyrosine kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase activator activity&apos; SubClassOf &apos;protein tyrosine kinase activator activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902911</classIRI>
<classLabel>protein kinase complex</classLabel>
<deletedAxiom>&apos;protein kinase complex&apos; SubClassOf &apos;capable of&apos; some &apos;protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein kinase complex&apos; SubClassOf &apos;transferase complex, transferring phosphorus-containing groups&apos;</deletedAxiom>
<deletedAxiom>&apos;protein kinase complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;protein kinase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0035118</classIRI>
<classLabel>material entity in digestive tract</classLabel>
<deletedAxiom>&apos;material entity in digestive tract&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000456</classIRI>
<classLabel>secretion of exocrine gland</classLabel>
<deletedAxiom>&apos;secretion of exocrine gland&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000467</classIRI>
<classLabel>anatomical system</classLabel>
<deletedAxiom>&apos;anatomical system&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901626</classIRI>
<classLabel>regulation of postsynaptic membrane organization</classLabel>
<deletedAxiom>&apos;regulation of postsynaptic membrane organization&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;postsynaptic membrane organization&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of postsynaptic membrane organization&apos; SubClassOf &apos;regulates&apos; some &apos;postsynaptic membrane organization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of postsynaptic membrane organization&apos; SubClassOf &apos;regulation of cellular component organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901627</classIRI>
<classLabel>negative regulation of postsynaptic membrane organization</classLabel>
<deletedAxiom>&apos;negative regulation of postsynaptic membrane organization&apos; SubClassOf &apos;regulation of postsynaptic membrane organization&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of postsynaptic membrane organization&apos; SubClassOf &apos;negative regulation of synapse organization&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of postsynaptic membrane organization&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;postsynaptic membrane organization&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of postsynaptic membrane organization&apos; SubClassOf &apos;negatively regulates&apos; some &apos;postsynaptic membrane organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000466</classIRI>
<classLabel>immaterial anatomical entity</classLabel>
<newAxiom>&apos;material anatomical entity&apos; DisjointWith &apos;immaterial anatomical entity&apos;</newAxiom>
<newAxiom>&apos;immaterial anatomical entity&apos; SubClassOf &apos;immaterial entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901628</classIRI>
<classLabel>positive regulation of postsynaptic membrane organization</classLabel>
<deletedAxiom>&apos;positive regulation of postsynaptic membrane organization&apos; SubClassOf &apos;regulation of postsynaptic membrane organization&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of postsynaptic membrane organization&apos; SubClassOf &apos;positively regulates&apos; some &apos;postsynaptic membrane organization&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of postsynaptic membrane organization&apos; SubClassOf &apos;positive regulation of cellular component organization&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of postsynaptic membrane organization&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;postsynaptic membrane organization&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000465</classIRI>
<classLabel>material anatomical entity</classLabel>
<newAxiom>&apos;material anatomical entity&apos; DisjointWith &apos;immaterial anatomical entity&apos;</newAxiom>
<newAxiom>&apos;material anatomical entity&apos; SubClassOf &apos;material entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000464</classIRI>
<classLabel>anatomical space</classLabel>
<deletedAxiom>&apos;anatomical space&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000463</classIRI>
<classLabel>organism substance</classLabel>
<deletedAxiom>&apos;organism substance&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0012463</classIRI>
<classLabel>cloacal lumen</classLabel>
<deletedAxiom>&apos;cloacal lumen&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0012465</classIRI>
<classLabel>lumen of terminal part of digestive tract</classLabel>
<deletedAxiom>&apos;lumen of terminal part of digestive tract&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000477</classIRI>
<classLabel>anatomical cluster</classLabel>
<deletedAxiom>&apos;anatomical cluster&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
<newAxiom>&apos;anatomical cluster&apos; SubClassOf http://purl.obolibrary.org/obo/UBERON_0034923</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000483</classIRI>
<classLabel>epithelium</classLabel>
<deletedAxiom>&apos;epithelium&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050731</classIRI>
<classLabel>positive regulation of peptidyl-tyrosine phosphorylation</classLabel>
<deletedAxiom>&apos;positive regulation of peptidyl-tyrosine phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;peptidyl-tyrosine phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of peptidyl-tyrosine phosphorylation&apos; SubClassOf &apos;positive regulation of protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of peptidyl-tyrosine phosphorylation&apos; SubClassOf &apos;positively regulates&apos; some &apos;peptidyl-tyrosine phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of peptidyl-tyrosine phosphorylation&apos; SubClassOf &apos;regulation of peptidyl-tyrosine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050732</classIRI>
<classLabel>negative regulation of peptidyl-tyrosine phosphorylation</classLabel>
<deletedAxiom>&apos;negative regulation of peptidyl-tyrosine phosphorylation&apos; SubClassOf &apos;regulation of peptidyl-tyrosine phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of peptidyl-tyrosine phosphorylation&apos; SubClassOf &apos;negative regulation of protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of peptidyl-tyrosine phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;peptidyl-tyrosine phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of peptidyl-tyrosine phosphorylation&apos; SubClassOf &apos;negatively regulates&apos; some &apos;peptidyl-tyrosine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050730</classIRI>
<classLabel>regulation of peptidyl-tyrosine phosphorylation</classLabel>
<deletedAxiom>&apos;regulation of peptidyl-tyrosine phosphorylation&apos; SubClassOf &apos;regulation of protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of peptidyl-tyrosine phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;peptidyl-tyrosine phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of peptidyl-tyrosine phosphorylation&apos; SubClassOf &apos;regulates&apos; some &apos;peptidyl-tyrosine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019900</classIRI>
<classLabel>kinase binding</classLabel>
<deletedAxiom>&apos;kinase binding&apos; SubClassOf &apos;enzyme binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019901</classIRI>
<classLabel>protein kinase binding</classLabel>
<deletedAxiom>&apos;protein kinase binding&apos; SubClassOf &apos;kinase binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0035159</classIRI>
<classLabel>entire surface of organism</classLabel>
<deletedAxiom>&apos;entire surface of organism&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005388</classIRI>
<classLabel>photoreceptor array</classLabel>
<deletedAxiom>&apos;photoreceptor array&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098655</classIRI>
<classLabel>cation transmembrane transport</classLabel>
<deletedAxiom>&apos;cation transmembrane transport&apos; EquivalentTo &apos;transport&apos; and (&apos;results in transport across&apos; some &apos;membrane&apos;) and (&apos;has primary input&apos; some &apos;cation&apos;)</deletedAxiom>
<newAxiom>&apos;cation transmembrane transport&apos; EquivalentTo &apos;transport&apos; and (&apos;results in transport across&apos; some &apos;membrane&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098656</classIRI>
<classLabel>anion transmembrane transport</classLabel>
<deletedAxiom>&apos;anion transmembrane transport&apos; SubClassOf &apos;ion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;anion transmembrane transport&apos; EquivalentTo &apos;transport&apos; and (&apos;results in transport across&apos; some &apos;membrane&apos;) and (&apos;has primary input&apos; some &apos;anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;anion transmembrane transport&apos; SubClassOf &apos;anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004064</classIRI>
<classLabel>neural tube basal plate</classLabel>
<deletedAxiom>&apos;neural tube basal plate&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098660</classIRI>
<classLabel>inorganic ion transmembrane transport</classLabel>
<deletedAxiom>&apos;inorganic ion transmembrane transport&apos; SubClassOf &apos;ion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;inorganic ion transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098661</classIRI>
<classLabel>inorganic anion transmembrane transport</classLabel>
<deletedAxiom>&apos;inorganic anion transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098662</classIRI>
<classLabel>inorganic cation transmembrane transport</classLabel>
<deletedAxiom>&apos;inorganic cation transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098664</classIRI>
<classLabel>G protein-coupled serotonin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;G protein-coupled serotonin receptor signaling pathway&apos; SubClassOf &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled serotonin receptor signaling pathway&apos; SubClassOf &apos;starts with&apos; some &apos;G protein-coupled serotonin receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled serotonin receptor signaling pathway&apos; EquivalentTo &apos;signal transduction&apos; and (&apos;starts with&apos; some &apos;G protein-coupled serotonin receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled serotonin receptor signaling pathway&apos; SubClassOf &apos;serotonin receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098665</classIRI>
<classLabel>serotonin receptor complex</classLabel>
<deletedAxiom>&apos;serotonin receptor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;serotonin receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;serotonin receptor complex&apos; SubClassOf &apos;receptor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;serotonin receptor complex&apos; SubClassOf &apos;capable of&apos; some &apos;serotonin receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098666</classIRI>
<classLabel>G protein-coupled serotonin receptor complex</classLabel>
<deletedAxiom>&apos;G protein-coupled serotonin receptor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;G protein-coupled serotonin receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled serotonin receptor complex&apos; SubClassOf &apos;serotonin receptor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled serotonin receptor complex&apos; SubClassOf &apos;capable of&apos; some &apos;G protein-coupled serotonin receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled serotonin receptor complex&apos; SubClassOf &apos;capable of part of&apos; some &apos;G protein-coupled serotonin receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004015</classIRI>
<classLabel>embryonic-extraembryonic boundary</classLabel>
<deletedAxiom>&apos;embryonic-extraembryonic boundary&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019887</classIRI>
<classLabel>protein kinase regulator activity</classLabel>
<deletedAxiom>&apos;protein kinase regulator activity&apos; SubClassOf &apos;has_part&apos; some &apos;protein kinase binding&apos;</deletedAxiom>
<deletedAxiom>&apos;protein kinase regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;regulates&apos; some &apos;protein kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;protein kinase regulator activity&apos; SubClassOf &apos;kinase regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein kinase regulator activity&apos; SubClassOf &apos;regulates&apos; some &apos;protein kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019899</classIRI>
<classLabel>enzyme binding</classLabel>
<deletedAxiom>&apos;enzyme binding&apos; SubClassOf &apos;protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032870</classIRI>
<classLabel>cellular response to hormone stimulus</classLabel>
<deletedAxiom>&apos;cellular response to hormone stimulus&apos; SubClassOf &apos;cellular response to endogenous stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular response to hormone stimulus&apos; SubClassOf &apos;cellular response to organic substance&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060089</classIRI>
<classLabel>molecular transducer activity</classLabel>
<deletedAxiom>&apos;molecular transducer activity&apos; SubClassOf &apos;molecular_function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001896</classIRI>
<classLabel>medulla oblongata</classLabel>
<deletedAxiom>&apos;medulla oblongata&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001775</classIRI>
<classLabel>cell activation</classLabel>
<newAxiom>&apos;cell activation&apos; SubClassOf &apos;multicellular organismal process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001776</classIRI>
<classLabel>leukocyte homeostasis</classLabel>
<newAxiom>&apos;leukocyte homeostasis&apos; SubClassOf &apos;only in taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;leukocyte homeostasis&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001833</classIRI>
<classLabel>lip</classLabel>
<deletedAxiom>&apos;lip&apos; SubClassOf &apos;part of&apos; some &apos;mouth&apos;</deletedAxiom>
<newAxiom>&apos;lip&apos; SubClassOf &apos;part of&apos; some &apos;mouth&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0013686</classIRI>
<classLabel>anatomical conduit space</classLabel>
<deletedAxiom>&apos;anatomical conduit space&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000383</classIRI>
<classLabel>musculature of body</classLabel>
<deletedAxiom>&apos;musculature of body&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0012375</classIRI>
<classLabel>subserosa</classLabel>
<deletedAxiom>&apos;subserosa&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000332</classIRI>
<classLabel>yellow bone marrow</classLabel>
<deletedAxiom>&apos;yellow bone marrow&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000353</classIRI>
<classLabel>parenchyma</classLabel>
<deletedAxiom>&apos;parenchyma&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000361</classIRI>
<classLabel>red bone marrow</classLabel>
<deletedAxiom>&apos;red bone marrow&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900449</classIRI>
<classLabel>regulation of glutamate receptor signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of glutamate receptor signaling pathway&apos; SubClassOf &apos;regulates&apos; some &apos;glutamate receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of glutamate receptor signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;glutamate receptor signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of glutamate receptor signaling pathway&apos; SubClassOf &apos;regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900450</classIRI>
<classLabel>negative regulation of glutamate receptor signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of glutamate receptor signaling pathway&apos; SubClassOf &apos;negatively regulates&apos; some &apos;glutamate receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of glutamate receptor signaling pathway&apos; SubClassOf &apos;regulation of glutamate receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of glutamate receptor signaling pathway&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of glutamate receptor signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;glutamate receptor signaling pathway&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900451</classIRI>
<classLabel>positive regulation of glutamate receptor signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of glutamate receptor signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;glutamate receptor signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of glutamate receptor signaling pathway&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of glutamate receptor signaling pathway&apos; SubClassOf &apos;regulation of glutamate receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of glutamate receptor signaling pathway&apos; SubClassOf &apos;positively regulates&apos; some &apos;glutamate receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006538</classIRI>
<classLabel>respiratory system fluid/secretion</classLabel>
<deletedAxiom>&apos;respiratory system fluid/secretion&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006535</classIRI>
<classLabel>skin secretion</classLabel>
<deletedAxiom>&apos;skin secretion&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_48560</classIRI>
<classLabel>dopaminergic agent</classLabel>
<deletedAxiom>&apos;dopaminergic agent&apos; SubClassOf &apos;neurotransmitter agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_48540</classIRI>
<classLabel>beta-adrenergic drug</classLabel>
<deletedAxiom>&apos;beta-adrenergic drug&apos; SubClassOf &apos;adrenergic agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051985</classIRI>
<classLabel>negative regulation of chromosome segregation</classLabel>
<deletedAxiom>&apos;negative regulation of chromosome segregation&apos; SubClassOf &apos;negative regulation of cellular process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of chromosome segregation&apos; SubClassOf &apos;negative regulation of cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051984</classIRI>
<classLabel>positive regulation of chromosome segregation</classLabel>
<deletedAxiom>&apos;positive regulation of chromosome segregation&apos; SubClassOf &apos;positive regulation of cellular process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of chromosome segregation&apos; SubClassOf &apos;positive regulation of cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051983</classIRI>
<classLabel>regulation of chromosome segregation</classLabel>
<deletedAxiom>&apos;regulation of chromosome segregation&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of chromosome segregation&apos; SubClassOf &apos;regulation of cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0018543</classIRI>
<classLabel>lumen of intestine</classLabel>
<deletedAxiom>&apos;lumen of intestine&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031401</classIRI>
<classLabel>positive regulation of protein modification process</classLabel>
<deletedAxiom>&apos;positive regulation of protein modification process&apos; SubClassOf &apos;positive regulation of protein metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein modification process&apos; SubClassOf &apos;positively regulates&apos; some &apos;protein modification process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein modification process&apos; SubClassOf &apos;regulation of protein modification process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein modification process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;protein modification process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031400</classIRI>
<classLabel>negative regulation of protein modification process</classLabel>
<deletedAxiom>&apos;negative regulation of protein modification process&apos; SubClassOf &apos;negative regulation of protein metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein modification process&apos; SubClassOf &apos;negatively regulates&apos; some &apos;protein modification process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein modification process&apos; SubClassOf &apos;regulation of protein modification process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein modification process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;protein modification process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006469</classIRI>
<classLabel>negative regulation of protein kinase activity</classLabel>
<deletedAxiom>&apos;negative regulation of protein kinase activity&apos; SubClassOf &apos;negative regulation of protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein kinase activity&apos; SubClassOf &apos;negative regulation of kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein kinase activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;protein kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein kinase activity&apos; SubClassOf &apos;regulation of protein kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006468</classIRI>
<classLabel>protein phosphorylation</classLabel>
<deletedAxiom>&apos;protein phosphorylation&apos; SubClassOf &apos;protein modification process&apos;</deletedAxiom>
<deletedAxiom>&apos;protein phosphorylation&apos; SubClassOf &apos;phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043401</classIRI>
<classLabel>steroid hormone mediated signaling pathway</classLabel>
<deletedAxiom>&apos;steroid hormone mediated signaling pathway&apos; SubClassOf &apos;part of&apos; some &apos;cellular response to steroid hormone stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;steroid hormone mediated signaling pathway&apos; SubClassOf &apos;hormone-mediated signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001759</classIRI>
<classLabel>vagus nerve</classLabel>
<deletedAxiom>&apos;vagus nerve&apos; SubClassOf &apos;has developmental contribution from&apos; some &apos;neural crest&apos;</deletedAxiom>
<newAxiom>&apos;vagus nerve&apos; SubClassOf &apos;structure with developmental contribution from neural crest&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0013727</classIRI>
<classLabel>notochordal fluid</classLabel>
<deletedAxiom>&apos;notochordal fluid&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001768</classIRI>
<classLabel>uvea</classLabel>
<deletedAxiom>&apos;uvea&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032782</classIRI>
<classLabel>bile acid secretion</classLabel>
<newAxiom>&apos;bile acid secretion&apos; SubClassOf &apos;monocarboxylic acid transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043412</classIRI>
<classLabel>macromolecule modification</classLabel>
<deletedAxiom>&apos;macromolecule modification&apos; SubClassOf &apos;macromolecule metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001774</classIRI>
<classLabel>skeletal muscle of trunk</classLabel>
<deletedAxiom>&apos;skeletal muscle of trunk&apos; SubClassOf &apos;part of&apos; some &apos;musculature of trunk&apos;</deletedAxiom>
<newAxiom>&apos;skeletal muscle of trunk&apos; SubClassOf &apos;part of&apos; some &apos;musculature of trunk&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001775</classIRI>
<classLabel>ciliary body</classLabel>
<deletedAxiom>&apos;ciliary body&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001653</classIRI>
<classLabel>peptide receptor activity</classLabel>
<deletedAxiom>&apos;peptide receptor activity&apos; SubClassOf &apos;signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some &apos;peptide&apos;)</deletedAxiom>
<deletedAxiom>&apos;peptide receptor activity&apos; SubClassOf &apos;has input&apos; some &apos;peptide&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide receptor activity&apos; SubClassOf &apos;has_part&apos; some &apos;peptide binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001708</classIRI>
<classLabel>jaw skeleton</classLabel>
<deletedAxiom>&apos;jaw skeleton&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001727</classIRI>
<classLabel>taste bud</classLabel>
<deletedAxiom>&apos;taste bud&apos; SubClassOf &apos;has_part&apos; some &apos;taste receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;taste bud&apos; SubClassOf &apos;part of&apos; some &apos;gustatory epithelium&apos;</deletedAxiom>
<newAxiom>&apos;taste bud&apos; SubClassOf &apos;part of&apos; some &apos;gustatory epithelium&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001723</classIRI>
<classLabel>tongue</classLabel>
<deletedAxiom>&apos;tongue&apos; SubClassOf &apos;part of&apos; some &apos;mouth&apos;</deletedAxiom>
<newAxiom>&apos;tongue&apos; SubClassOf &apos;part of&apos; some &apos;mouth&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097272</classIRI>
<classLabel>ammonium homeostasis</classLabel>
<deletedAxiom>&apos;ammonium homeostasis&apos; SubClassOf &apos;monovalent inorganic cation homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;ammonium homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001731</classIRI>
<classLabel>cavity of pharynx</classLabel>
<deletedAxiom>&apos;cavity of pharynx&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097275</classIRI>
<classLabel>cellular ammonium homeostasis</classLabel>
<deletedAxiom>&apos;cellular ammonium homeostasis&apos; SubClassOf &apos;cellular monovalent inorganic cation homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;cellular ammonium homeostasis&apos; SubClassOf &apos;cellular chemical homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031399</classIRI>
<classLabel>regulation of protein modification process</classLabel>
<deletedAxiom>&apos;regulation of protein modification process&apos; SubClassOf &apos;regulation of protein metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein modification process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;protein modification process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of protein modification process&apos; SubClassOf &apos;regulates&apos; some &apos;protein modification process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904065</classIRI>
<classLabel>G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission</classLabel>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission&apos; SubClassOf &apos;G protein-coupled acetylcholine receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission&apos; EquivalentTo &apos;G protein-coupled acetylcholine receptor signaling pathway&apos; and (&apos;part of&apos; some &apos;positive regulation of acetylcholine secretion, neurotransmission&apos;)</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission&apos; SubClassOf &apos;part of&apos; some &apos;positive regulation of acetylcholine secretion, neurotransmission&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004647</classIRI>
<classLabel>liver lobule</classLabel>
<deletedAxiom>&apos;liver lobule&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042053</classIRI>
<classLabel>regulation of dopamine metabolic process</classLabel>
<deletedAxiom>&apos;regulation of dopamine metabolic process&apos; SubClassOf &apos;regulation of nitrogen compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of dopamine metabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;dopamine metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of dopamine metabolic process&apos; SubClassOf &apos;regulates&apos; some &apos;dopamine metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005913</classIRI>
<classLabel>zone of bone organ</classLabel>
<deletedAxiom>&apos;zone of bone organ&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002049</classIRI>
<classLabel>vasculature</classLabel>
<deletedAxiom>&apos;vasculature&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036211</classIRI>
<classLabel>protein modification process</classLabel>
<deletedAxiom>&apos;protein modification process&apos; SubClassOf &apos;protein metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;protein modification process&apos; SubClassOf &apos;macromolecule modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002067</classIRI>
<classLabel>dermis</classLabel>
<deletedAxiom>&apos;dermis&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002025</classIRI>
<classLabel>stratum basale of epidermis</classLabel>
<deletedAxiom>&apos;stratum basale of epidermis&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0035804</classIRI>
<classLabel>future mouth</classLabel>
<deletedAxiom>&apos;future mouth&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0035809</classIRI>
<classLabel>serous cavity</classLabel>
<deletedAxiom>&apos;serous cavity&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0011823</classIRI>
<classLabel>dense connective tissue</classLabel>
<deletedAxiom>&apos;dense connective tissue&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0035819</classIRI>
<classLabel>abdominopelvic cavity</classLabel>
<deletedAxiom>&apos;abdominopelvic cavity&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097104</classIRI>
<classLabel>postsynaptic membrane assembly</classLabel>
<deletedAxiom>&apos;postsynaptic membrane assembly&apos; EquivalentTo &apos;cellular process&apos; and (&apos;results in assembly of&apos; some &apos;postsynaptic membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;postsynaptic membrane assembly&apos; SubClassOf &apos;membrane assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic membrane assembly&apos; SubClassOf &apos;part of&apos; some &apos;postsynapse assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic membrane assembly&apos; SubClassOf &apos;results in assembly of&apos; some &apos;postsynaptic membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic membrane assembly&apos; SubClassOf &apos;postsynaptic membrane organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008203</classIRI>
<classLabel>pelvic cavity</classLabel>
<deletedAxiom>&apos;pelvic cavity&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002072</classIRI>
<classLabel>hypodermis</classLabel>
<deletedAxiom>&apos;hypodermis&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005009</classIRI>
<classLabel>insulin receptor activity</classLabel>
<deletedAxiom>&apos;insulin receptor activity&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor activity&apos; SubClassOf &apos;has_part&apos; some &apos;insulin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor activity&apos; SubClassOf &apos;protein-hormone receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some &apos;insulin gene translation product&apos;)</deletedAxiom>
<deletedAxiom>&apos;insulin receptor activity&apos; SubClassOf &apos;part of&apos; some &apos;insulin receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor activity&apos; SubClassOf &apos;only in taxon&apos; some &apos;Eumetazoa&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor activity&apos; SubClassOf &apos;transmembrane receptor protein tyrosine kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor activity&apos; SubClassOf &apos;has input&apos; some &apos;insulin gene translation product&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_57887</classIRI>
<classLabel>tryptaminium</classLabel>
<deletedAxiom>&apos;tryptaminium&apos; SubClassOf &apos;ammonium ion derivative&apos;</deletedAxiom>
<newAxiom>&apos;tryptaminium&apos; SubClassOf &apos;primary ammonium ion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030002</classIRI>
<classLabel>cellular anion homeostasis</classLabel>
<deletedAxiom>&apos;cellular anion homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;cellular anion homeostasis&apos; SubClassOf &apos;cellular ion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular anion homeostasis&apos; SubClassOf &apos;anion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045964</classIRI>
<classLabel>positive regulation of dopamine metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of dopamine metabolic process&apos; SubClassOf &apos;positive regulation of nitrogen compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dopamine metabolic process&apos; SubClassOf &apos;regulation of dopamine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dopamine metabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;dopamine metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dopamine metabolic process&apos; SubClassOf &apos;positively regulates&apos; some &apos;dopamine metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045963</classIRI>
<classLabel>negative regulation of dopamine metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of dopamine metabolic process&apos; SubClassOf &apos;negatively regulates&apos; some &apos;dopamine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dopamine metabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;dopamine metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dopamine metabolic process&apos; SubClassOf &apos;regulation of dopamine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dopamine metabolic process&apos; SubClassOf &apos;negative regulation of nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097120</classIRI>
<classLabel>receptor localization to synapse</classLabel>
<deletedAxiom>&apos;receptor localization to synapse&apos; SubClassOf &apos;has primary input&apos; some &apos;plasma membrane signaling receptor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;receptor localization to synapse&apos; SubClassOf &apos;protein-containing complex localization&apos;</deletedAxiom>
<deletedAxiom>&apos;receptor localization to synapse&apos; SubClassOf &apos;has target end location&apos; some &apos;synapse&apos;</deletedAxiom>
<deletedAxiom>&apos;receptor localization to synapse&apos; EquivalentTo &apos;localization&apos; and (&apos;has target end location&apos; some &apos;synapse&apos;) and (&apos;has primary input&apos; some &apos;plasma membrane signaling receptor complex&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030003</classIRI>
<classLabel>cellular cation homeostasis</classLabel>
<deletedAxiom>&apos;cellular cation homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;cation&apos;)</deletedAxiom>
<newAxiom>&apos;cellular cation homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030004</classIRI>
<classLabel>cellular monovalent inorganic cation homeostasis</classLabel>
<deletedAxiom>&apos;cellular monovalent inorganic cation homeostasis&apos; SubClassOf &apos;monovalent inorganic cation homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular monovalent inorganic cation homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monovalent inorganic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;cellular monovalent inorganic cation homeostasis&apos; SubClassOf &apos;cellular cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0011860</classIRI>
<classLabel>collection of collagen fibrils</classLabel>
<deletedAxiom>&apos;collection of collagen fibrils&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0011892</classIRI>
<classLabel>anterior uvea</classLabel>
<deletedAxiom>&apos;anterior uvea&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_18243</classIRI>
<classLabel>dopamine</classLabel>
<deletedAxiom>&apos;dopamine&apos; SubClassOf &apos;has role&apos; some &apos;Escherichia coli metabolite&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine&apos; SubClassOf &apos;has role&apos; some &apos;mouse metabolite&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine&apos; SubClassOf &apos;has role&apos; some &apos;cardiotonic drug&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine&apos; SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of some &apos;dopaminium(1+)&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine&apos; SubClassOf &apos;catecholamine&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine&apos; SubClassOf &apos;has role&apos; some &apos;human metabolite&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine&apos; SubClassOf &apos;has role&apos; some &apos;sympathomimetic agent&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine&apos; SubClassOf &apos;has role&apos; some &apos;beta-adrenergic agonist&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine&apos; SubClassOf &apos;has role&apos; some &apos;dopaminergic agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099637</classIRI>
<classLabel>neurotransmitter receptor transport</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor transport&apos; SubClassOf &apos;has primary input&apos; some &apos;neurotransmitter receptor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor transport&apos; SubClassOf &apos;protein transport&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor transport&apos; SubClassOf &apos;protein-containing complex localization&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor transport&apos; EquivalentTo &apos;protein transport&apos; and (&apos;has primary input&apos; some &apos;neurotransmitter receptor complex&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099601</classIRI>
<classLabel>regulation of neurotransmitter receptor activity</classLabel>
<deletedAxiom>&apos;regulation of neurotransmitter receptor activity&apos; SubClassOf &apos;regulation of signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of neurotransmitter receptor activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;neurotransmitter receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of neurotransmitter receptor activity&apos; SubClassOf &apos;regulates&apos; some &apos;neurotransmitter receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099602</classIRI>
<classLabel>neurotransmitter receptor regulator activity</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor regulator activity&apos; SubClassOf &apos;regulates&apos; some &apos;neurotransmitter receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor regulator activity&apos; SubClassOf &apos;signaling receptor regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor regulator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;regulates&apos; some &apos;neurotransmitter receptor activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018212</classIRI>
<classLabel>peptidyl-tyrosine modification</classLabel>
<deletedAxiom>&apos;peptidyl-tyrosine modification&apos; SubClassOf &apos;peptidyl-amino acid modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0035763</classIRI>
<classLabel>cavity of cardiac chamber</classLabel>
<deletedAxiom>&apos;cavity of cardiac chamber&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061099</classIRI>
<classLabel>negative regulation of protein tyrosine kinase activity</classLabel>
<deletedAxiom>&apos;negative regulation of protein tyrosine kinase activity&apos; SubClassOf &apos;regulation of protein tyrosine kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein tyrosine kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;protein tyrosine kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein tyrosine kinase activity&apos; SubClassOf &apos;negative regulation of protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein tyrosine kinase activity&apos; SubClassOf &apos;negative regulation of peptidyl-tyrosine phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein tyrosine kinase activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;protein tyrosine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061098</classIRI>
<classLabel>positive regulation of protein tyrosine kinase activity</classLabel>
<deletedAxiom>&apos;positive regulation of protein tyrosine kinase activity&apos; SubClassOf &apos;positive regulation of protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein tyrosine kinase activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;protein tyrosine kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein tyrosine kinase activity&apos; SubClassOf &apos;positive regulation of peptidyl-tyrosine phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein tyrosine kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;protein tyrosine kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein tyrosine kinase activity&apos; SubClassOf &apos;regulation of protein tyrosine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061097</classIRI>
<classLabel>regulation of protein tyrosine kinase activity</classLabel>
<deletedAxiom>&apos;regulation of protein tyrosine kinase activity&apos; SubClassOf &apos;regulation of peptidyl-tyrosine phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein tyrosine kinase activity&apos; SubClassOf &apos;regulation of protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein tyrosine kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;protein tyrosine kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of protein tyrosine kinase activity&apos; SubClassOf &apos;regulates&apos; some &apos;protein tyrosine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045860</classIRI>
<classLabel>positive regulation of protein kinase activity</classLabel>
<deletedAxiom>&apos;positive regulation of protein kinase activity&apos; SubClassOf &apos;positive regulation of protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;protein kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein kinase activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein kinase activity&apos; SubClassOf &apos;positive regulation of kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein kinase activity&apos; SubClassOf &apos;regulation of protein kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045859</classIRI>
<classLabel>regulation of protein kinase activity</classLabel>
<deletedAxiom>&apos;regulation of protein kinase activity&apos; SubClassOf &apos;regulation of kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein kinase activity&apos; SubClassOf &apos;regulation of protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;protein kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of protein kinase activity&apos; SubClassOf &apos;regulates&apos; some &apos;protein kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043235</classIRI>
<classLabel>receptor complex</classLabel>
<deletedAxiom>&apos;receptor complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<deletedAxiom>&apos;receptor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;signaling receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;receptor complex&apos; SubClassOf &apos;capable of&apos; some &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0011772</classIRI>
<classLabel>lower jaw opening</classLabel>
<deletedAxiom>&apos;lower jaw opening&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043129</classIRI>
<classLabel>surfactant homeostasis</classLabel>
<deletedAxiom>&apos;surfactant homeostasis&apos; SubClassOf &apos;chemical homeostasis within a tissue&apos;</deletedAxiom>
<newAxiom>&apos;surfactant homeostasis&apos; SubClassOf &apos;multicellular organismal homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045780</classIRI>
<classLabel>positive regulation of bone resorption</classLabel>
<deletedAxiom>&apos;positive regulation of bone resorption&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of bone resorption&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018193</classIRI>
<classLabel>peptidyl-amino acid modification</classLabel>
<deletedAxiom>&apos;peptidyl-amino acid modification&apos; SubClassOf &apos;has input&apos; some &apos;amino-acid residue&apos;</deletedAxiom>
<deletedAxiom>&apos;peptidyl-amino acid modification&apos; SubClassOf &apos;protein modification process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0022293</classIRI>
<classLabel>reproductive gland secretion</classLabel>
<deletedAxiom>&apos;reproductive gland secretion&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0011595</classIRI>
<classLabel>jaw region</classLabel>
<deletedAxiom>&apos;jaw region&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003126</classIRI>
<classLabel>trachea</classLabel>
<deletedAxiom>&apos;trachea&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080144</classIRI>
<classLabel>amino acid homeostasis</classLabel>
<deletedAxiom>&apos;amino acid homeostasis&apos; SubClassOf &apos;chemical homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;amino acid homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;amino acid&apos;)</deletedAxiom>
<newAxiom>&apos;amino acid homeostasis&apos; EquivalentTo &apos;cellular chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;amino acid&apos;)</newAxiom>
<newAxiom>&apos;amino acid homeostasis&apos; SubClassOf &apos;cellular chemical homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051633</classIRI>
<classLabel>positive regulation of acetylcholine uptake</classLabel>
<deletedAxiom>&apos;positive regulation of acetylcholine uptake&apos; SubClassOf &apos;positive regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051632</classIRI>
<classLabel>negative regulation of acetylcholine uptake</classLabel>
<deletedAxiom>&apos;negative regulation of acetylcholine uptake&apos; SubClassOf &apos;negative regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051631</classIRI>
<classLabel>regulation of acetylcholine uptake</classLabel>
<deletedAxiom>&apos;regulation of acetylcholine uptake&apos; SubClassOf &apos;regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005742</classIRI>
<classLabel>adventitia</classLabel>
<deletedAxiom>&apos;adventitia&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_36235</classIRI>
<newAxiom>http://purl.obolibrary.org/obo/CHEBI_36235 SubClassOf &apos;steroid acid anion&apos;</newAxiom>
<newAxiom>http://purl.obolibrary.org/obo/CHEBI_36235 SubClassOf &apos;monocarboxylic acid anion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003104</classIRI>
<classLabel>mesenchyme</classLabel>
<deletedAxiom>&apos;mesenchyme&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005764</classIRI>
<classLabel>acellular membrane</classLabel>
<deletedAxiom>&apos;acellular membrane&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000949</classIRI>
<classLabel>endocrine system</classLabel>
<deletedAxiom>&apos;endocrine system&apos; EquivalentTo &apos;anatomical system&apos; and (&apos;capable of&apos; some &apos;endocrine process&apos;)</deletedAxiom>
<deletedAxiom>&apos;endocrine system&apos; SubClassOf &apos;anatomical system&apos;</deletedAxiom>
<newAxiom>&apos;endocrine system&apos; SubClassOf http://purl.obolibrary.org/obo/UBERON_0015204</newAxiom>
<newAxiom>&apos;endocrine system&apos; EquivalentTo http://purl.obolibrary.org/obo/UBERON_0015203 and (&apos;capable of&apos; some &apos;endocrine process&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099528</classIRI>
<classLabel>G protein-coupled neurotransmitter receptor activity</classLabel>
<deletedAxiom>&apos;G protein-coupled neurotransmitter receptor activity&apos; SubClassOf &apos;G protein-coupled receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled neurotransmitter receptor activity&apos; SubClassOf &apos;neurotransmitter receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099529</classIRI>
<classLabel>neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential&apos; EquivalentTo &apos;neurotransmitter receptor activity&apos; and (&apos;part of&apos; some &apos;regulation of postsynaptic membrane potential&apos;)</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential&apos; SubClassOf &apos;postsynaptic neurotransmitter receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential&apos; SubClassOf &apos;part of&apos; some &apos;regulation of postsynaptic membrane potential&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099530</classIRI>
<classLabel>G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential</classLabel>
<deletedAxiom>&apos;G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential&apos; EquivalentTo &apos;G protein-coupled receptor activity&apos; and (&apos;part of&apos; some &apos;regulation of postsynaptic membrane potential&apos;)</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential&apos; SubClassOf &apos;part of&apos; some &apos;regulation of postsynaptic membrane potential&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential&apos; SubClassOf &apos;G protein-coupled receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential&apos; SubClassOf &apos;occurs in&apos; some &apos;postsynaptic membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140231</classIRI>
<classLabel>anterograde axonal transport of neurotransmitter receptor complex</classLabel>
<deletedAxiom>&apos;anterograde axonal transport of neurotransmitter receptor complex&apos; SubClassOf &apos;neurotransmitter receptor transport&apos;</deletedAxiom>
<deletedAxiom>&apos;anterograde axonal transport of neurotransmitter receptor complex&apos; EquivalentTo &apos;transport&apos; and (&apos;occurs in&apos; some &apos;axon cytoplasm&apos;) and (&apos;has target end location&apos; some &apos;presynapse&apos;) and (&apos;results in transport along&apos; some &apos;microtubule&apos;) and (&apos;has primary input&apos; some &apos;neurotransmitter receptor complex&apos;)</deletedAxiom>
<deletedAxiom>&apos;anterograde axonal transport of neurotransmitter receptor complex&apos; SubClassOf &apos;receptor localization to synapse&apos;</deletedAxiom>
<deletedAxiom>&apos;anterograde axonal transport of neurotransmitter receptor complex&apos; SubClassOf &apos;anterograde axonal protein transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099579</classIRI>
<classLabel>G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential</classLabel>
<deletedAxiom>&apos;G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential&apos; SubClassOf &apos;neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential&apos; EquivalentTo &apos;G protein-coupled neurotransmitter receptor activity&apos; and (&apos;part of&apos; some &apos;regulation of postsynaptic membrane potential&apos;)</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential&apos; SubClassOf &apos;G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential&apos; SubClassOf &apos;G protein-coupled neurotransmitter receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099589</classIRI>
<classLabel>serotonin receptor activity</classLabel>
<deletedAxiom>&apos;serotonin receptor activity&apos; SubClassOf &apos;has input&apos; some &apos;serotonin(1+)&apos;</deletedAxiom>
<deletedAxiom>&apos;serotonin receptor activity&apos; SubClassOf &apos;transmembrane signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;serotonin receptor activity&apos; EquivalentTo &apos;transmembrane signaling receptor activity&apos; and (&apos;has input&apos; some &apos;serotonin(1+)&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018108</classIRI>
<classLabel>peptidyl-tyrosine phosphorylation</classLabel>
<deletedAxiom>&apos;peptidyl-tyrosine phosphorylation&apos; SubClassOf &apos;protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;peptidyl-tyrosine phosphorylation&apos; SubClassOf &apos;peptidyl-tyrosine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032412</classIRI>
<classLabel>regulation of ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;regulation of ion transmembrane transporter activity&apos; SubClassOf &apos;regulation of ion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010362</classIRI>
<classLabel>endoskeleton</classLabel>
<deletedAxiom>&apos;endoskeleton&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0035639</classIRI>
<classLabel>ocular adnexa</classLabel>
<deletedAxiom>&apos;ocular adnexa&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045745</classIRI>
<classLabel>positive regulation of G protein-coupled receptor signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of G protein-coupled receptor signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;G protein-coupled receptor signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;positively regulates&apos; some &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;regulation of G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045744</classIRI>
<classLabel>negative regulation of G protein-coupled receptor signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;regulation of G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of G protein-coupled receptor signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;G protein-coupled receptor signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;negatively regulates&apos; some &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070634</classIRI>
<classLabel>transepithelial ammonium transport</classLabel>
<deletedAxiom>&apos;transepithelial ammonium transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032364</classIRI>
<classLabel>oxygen homeostasis</classLabel>
<deletedAxiom>&apos;oxygen homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;dioxygen&apos;)</deletedAxiom>
<deletedAxiom>&apos;oxygen homeostasis&apos; SubClassOf &apos;gas homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;oxygen homeostasis&apos; SubClassOf &apos;cellular chemical homeostasis&apos;</newAxiom>
<newAxiom>&apos;oxygen homeostasis&apos; EquivalentTo &apos;cellular chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;dioxygen&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009142</classIRI>
<classLabel>entire embryonic mesenchyme</classLabel>
<deletedAxiom>&apos;entire embryonic mesenchyme&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070661</classIRI>
<classLabel>leukocyte proliferation</classLabel>
<newAxiom>&apos;leukocyte proliferation&apos; SubClassOf &apos;only in taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;leukocyte proliferation&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010161</classIRI>
<classLabel>lumen of blood vessel</classLabel>
<deletedAxiom>&apos;lumen of blood vessel&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006909</classIRI>
<classLabel>lumen of digestive tract</classLabel>
<deletedAxiom>&apos;lumen of digestive tract&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055083</classIRI>
<classLabel>monovalent inorganic anion homeostasis</classLabel>
<deletedAxiom>&apos;monovalent inorganic anion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;monovalent inorganic anion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;monovalent inorganic anion&apos;</deletedAxiom>
<deletedAxiom>&apos;monovalent inorganic anion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monovalent inorganic anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;monovalent inorganic anion homeostasis&apos; SubClassOf &apos;anion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055081</classIRI>
<classLabel>anion homeostasis</classLabel>
<deletedAxiom>&apos;anion homeostasis&apos; SubClassOf &apos;ion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;anion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;anion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;anion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055080</classIRI>
<classLabel>cation homeostasis</classLabel>
<deletedAxiom>&apos;cation homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;cation homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;cation&apos;</deletedAxiom>
<newAxiom>&apos;cation homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monoatomic cation&apos;)</newAxiom>
<newAxiom>&apos;cation homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;monoatomic cation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015874</classIRI>
<classLabel>norepinephrine transport</classLabel>
<newAxiom>&apos;norepinephrine transport&apos; SubClassOf &apos;organic cation transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015872</classIRI>
<classLabel>dopamine transport</classLabel>
<deletedAxiom>&apos;dopamine transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has primary input&apos; some &apos;dopaminium(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;dopamine transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine transport&apos; SubClassOf &apos;has primary input&apos; some &apos;dopaminium(1+)&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055063</classIRI>
<classLabel>sulfate ion homeostasis</classLabel>
<deletedAxiom>&apos;sulfate ion homeostasis&apos; SubClassOf &apos;divalent inorganic anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;sulfate ion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055062</classIRI>
<classLabel>phosphate ion homeostasis</classLabel>
<deletedAxiom>&apos;phosphate ion homeostasis&apos; SubClassOf &apos;trivalent inorganic anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;phosphate ion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005688</classIRI>
<classLabel>lens vesicle cavity</classLabel>
<deletedAxiom>&apos;lens vesicle cavity&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055067</classIRI>
<classLabel>monovalent inorganic cation homeostasis</classLabel>
<deletedAxiom>&apos;monovalent inorganic cation homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;monovalent inorganic cation&apos;</deletedAxiom>
<deletedAxiom>&apos;monovalent inorganic cation homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monovalent inorganic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;monovalent inorganic cation homeostasis&apos; SubClassOf &apos;cation homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;monovalent inorganic cation homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003023</classIRI>
<classLabel>pontine tegmentum</classLabel>
<deletedAxiom>&apos;pontine tegmentum&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055078</classIRI>
<classLabel>sodium ion homeostasis</classLabel>
<deletedAxiom>&apos;sodium ion homeostasis&apos; SubClassOf &apos;monovalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003084</classIRI>
<classLabel>heart primordium</classLabel>
<deletedAxiom>&apos;heart primordium&apos; SubClassOf &apos;primordium&apos;</deletedAxiom>
<newAxiom>&apos;heart primordium&apos; SubClassOf &apos;primordium&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003083</classIRI>
<classLabel>trunk neural crest</classLabel>
<deletedAxiom>&apos;trunk neural crest&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003099</classIRI>
<classLabel>cranial neural crest</classLabel>
<deletedAxiom>&apos;cranial neural crest&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010966</classIRI>
<classLabel>regulation of phosphate transport</classLabel>
<deletedAxiom>&apos;regulation of phosphate transport&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of phosphate transport&apos; SubClassOf &apos;regulation of transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033602</classIRI>
<classLabel>negative regulation of dopamine secretion</classLabel>
<deletedAxiom>&apos;negative regulation of dopamine secretion&apos; SubClassOf &apos;negative regulation of ion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dopamine secretion&apos; SubClassOf &apos;negatively regulates&apos; some &apos;dopamine secretion&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dopamine secretion&apos; SubClassOf &apos;regulation of dopamine secretion&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dopamine secretion&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;dopamine secretion&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dopamine secretion&apos; SubClassOf &apos;negative regulation of secretion by cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033603</classIRI>
<classLabel>positive regulation of dopamine secretion</classLabel>
<deletedAxiom>&apos;positive regulation of dopamine secretion&apos; SubClassOf &apos;positive regulation of secretion by cell&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dopamine secretion&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;dopamine secretion&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dopamine secretion&apos; SubClassOf &apos;positive regulation of ion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dopamine secretion&apos; SubClassOf &apos;positively regulates&apos; some &apos;dopamine secretion&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dopamine secretion&apos; SubClassOf &apos;regulation of dopamine secretion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0086103</classIRI>
<classLabel>G protein-coupled receptor signaling pathway involved in heart process</classLabel>
<deletedAxiom>&apos;G protein-coupled receptor signaling pathway involved in heart process&apos; SubClassOf &apos;part of&apos; some &apos;heart process&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled receptor signaling pathway involved in heart process&apos; SubClassOf &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;G protein-coupled receptor signaling pathway involved in heart process&apos; EquivalentTo &apos;G protein-coupled receptor signaling pathway&apos; and (&apos;part of&apos; some &apos;heart process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0011566</classIRI>
<classLabel>lumen of esophagus</classLabel>
<deletedAxiom>&apos;lumen of esophagus&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0034923</classIRI>
<classLabel>disconnected anatomical group</classLabel>
<newAxiom>'disconnected anatomical group' SubClassOf 'material anatomical entity'</newAxiom>
<newAxiom>'disconnected anatomical group' SubClassOf 'composed primarily of' some 'anatomical structure'</newAxiom>
<newAxiom>'disconnected anatomical group' SubClassOf 'has component' min 2 'anatomical structure'</newAxiom>
<newAxiom>'disconnected anatomical group' SubClassOf 'has quality' some 'disconnected'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_33569</classIRI>
<classLabel>noradrenaline</classLabel>
<newAxiom>'noradrenaline' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of some 'noradrenaline(1+)'</newAxiom>
<newAxiom>'noradrenaline' SubClassOf 'catecholamine'</newAxiom>
<newAxiom>'noradrenaline' SubClassOf 'has role' some 'human xenobiotic metabolite'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_33571</classIRI>
<classLabel>(S)-noradrenaline</classLabel>
<newAxiom>'(S)-noradrenaline' SubClassOf 'noradrenaline'</newAxiom>
<newAxiom>'(S)-noradrenaline' SubClassOf http://purl.obolibrary.org/obo/chebi#is_enantiomer_of some '(R)-noradrenaline'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_35569</classIRI>
<classLabel>alpha-adrenergic agonist</classLabel>
<newAxiom>'alpha-adrenergic agonist' SubClassOf 'adrenergic agonist'</newAxiom>
<newAxiom>'alpha-adrenergic agonist' SubClassOf 'alpha-adrenergic drug'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_76206</classIRI>
<classLabel>xenobiotic metabolite</classLabel>
<newAxiom>'xenobiotic metabolite' SubClassOf 'metabolite'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0003001</classIRI>
<classLabel>bistratified retinal ganglion cell</classLabel>
<newAxiom>'bistratified retinal ganglion cell' SubClassOf 'bistratified cell'</newAxiom>
<newAxiom>'bistratified retinal ganglion cell' SubClassOf 'retinal ganglion cell'</newAxiom>
<newAxiom>'bistratified retinal ganglion cell' EquivalentTo 'retinal ganglion cell' and ('bearer of' some 'bistratified dendrite cell morphology')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010009</classIRI>
<classLabel>aggregate regional part of brain</classLabel>
<newAxiom>'aggregate regional part of brain' EquivalentTo 'disconnected anatomical group' and ('part of' some 'brain') and ('has member' some 'regional part of brain')</newAxiom>
<newAxiom>'aggregate regional part of brain' SubClassOf 'part of' some 'brain'</newAxiom>
<newAxiom>'aggregate regional part of brain' SubClassOf 'has member' some 'regional part of brain'</newAxiom>
<newAxiom>'aggregate regional part of brain' SubClassOf 'disconnected anatomical group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_4030029</classIRI>
<classLabel>blood lymphocyte</classLabel>
<newAxiom>'blood lymphocyte' SubClassOf 'peripheral blood mononuclear cell'</newAxiom>
<newAxiom>'blood lymphocyte' EquivalentTo 'lymphocyte' and ('part of' some 'blood')</newAxiom>
<newAxiom>'blood lymphocyte' SubClassOf 'lymphocyte'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_166902</classIRI>
<classLabel>noradrenaline(1+)</classLabel>
<newAxiom>'noradrenaline(1+)' SubClassOf 'ammonium ion derivative'</newAxiom>
<newAxiom>'noradrenaline(1+)' SubClassOf 'organic cation'</newAxiom>
<newAxiom>'noradrenaline(1+)' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of some 'noradrenaline'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_48539</classIRI>
<classLabel>alpha-adrenergic drug</classLabel>
<newAxiom>'alpha-adrenergic drug' SubClassOf 'adrenergic agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_76967</classIRI>
<classLabel>human xenobiotic metabolite</classLabel>
<newAxiom>'human xenobiotic metabolite' SubClassOf 'human metabolite'</newAxiom>
<newAxiom>'human xenobiotic metabolite' SubClassOf 'xenobiotic metabolite'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0015203</classIRI>
<classLabel>non-connected functional system</classLabel>
<newAxiom>'non-connected functional system' SubClassOf 'disconnected anatomical group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0015204</classIRI>
<classLabel>glandular system</classLabel>
<newAxiom>'glandular system' EquivalentTo 'non-connected functional system' and ('composed primarily of' some 'gland')</newAxiom>
<newAxiom>'glandular system' SubClassOf 'composed primarily of' some 'gland'</newAxiom>
<newAxiom>'glandular system' SubClassOf 'non-connected functional system'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_8480026</classIRI>
<classLabel>skin of iliac crest region</classLabel>
<newAxiom>'skin of iliac crest region' SubClassOf 'part of' some 'pelvic girdle bone/zone'</newAxiom>
<newAxiom>'skin of iliac crest region' EquivalentTo 'zone of skin' and ('part of' some 'pelvic girdle bone/zone')</newAxiom>
<newAxiom>'skin of iliac crest region' SubClassOf 'skin of pelvis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_8480025</classIRI>
<classLabel>skin of clavicle region</classLabel>
<newAxiom>'skin of clavicle region' EquivalentTo 'zone of skin' and ('part of' some 'pectoral girdle region')</newAxiom>
<newAxiom>'skin of clavicle region' SubClassOf 'zone of skin'</newAxiom>
<newAxiom>'skin of clavicle region' SubClassOf 'part of' some 'pectoral girdle region'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_8480029</classIRI>
<classLabel>skin of external genitalia</classLabel>
<newAxiom>'skin of external genitalia' SubClassOf 'zone of skin'</newAxiom>
<newAxiom>'skin of external genitalia' SubClassOf 'part of' some 'external genitalia'</newAxiom>
<newAxiom>'skin of external genitalia' SubClassOf 'reproductive structure'</newAxiom>
<newAxiom>'skin of external genitalia' EquivalentTo 'zone of skin' and ('part of' some 'external genitalia')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_8480037</classIRI>
<classLabel>subserosa of uterine tube</classLabel>
<newAxiom>'subserosa of uterine tube' SubClassOf 'reproductive structure'</newAxiom>
<newAxiom>'subserosa of uterine tube' EquivalentTo 'subserosa' and ('part of' some 'fallopian tube')</newAxiom>
<newAxiom>'subserosa of uterine tube' SubClassOf 'subserosa'</newAxiom>
<newAxiom>'subserosa of uterine tube' SubClassOf 'part of' some 'fallopian tube'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_50514</classIRI>
<classLabel>vasoconstrictor agent</classLabel>
<newAxiom>'vasoconstrictor agent' SubClassOf 'cardiovascular drug'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0004247</classIRI>
<classLabel>bistratified cell</classLabel>
<newAxiom>'bistratified cell' SubClassOf 'neuron'</newAxiom>
<newAxiom>'bistratified cell' SubClassOf 'bearer of' some 'bistratified dendrite cell morphology'</newAxiom>
<newAxiom>'bistratified cell' EquivalentTo 'neuron' and ('bearer of' some 'bistratified dendrite cell morphology')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0004246</classIRI>
<classLabel>monostratified cell</classLabel>
<newAxiom>'monostratified cell' SubClassOf 'central nervous system neuron'</newAxiom>
<newAxiom>'monostratified cell' SubClassOf 'bearer of' some 'monostratified dendrite cell morphology'</newAxiom>
<newAxiom>'monostratified cell' EquivalentTo 'neuron' and ('bearer of' some 'monostratified dendrite cell morphology') and ('has soma location' some 'central nervous system')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_18357</classIRI>
<classLabel>(R)-noradrenaline</classLabel>
<newAxiom>'(R)-noradrenaline' SubClassOf 'has role' some 'vasoconstrictor agent'</newAxiom>
<newAxiom>'(R)-noradrenaline' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of some '(R)-noradrenaline(1+)'</newAxiom>
<newAxiom>'(R)-noradrenaline' SubClassOf 'has role' some 'sympathomimetic agent'</newAxiom>
<newAxiom>'(R)-noradrenaline' SubClassOf 'has role' some 'alpha-adrenergic agonist'</newAxiom>
<newAxiom>'(R)-noradrenaline' SubClassOf 'has role' some 'neurotransmitter'</newAxiom>
<newAxiom>'(R)-noradrenaline' SubClassOf 'has role' some 'mouse metabolite'</newAxiom>
<newAxiom>'(R)-noradrenaline' SubClassOf http://purl.obolibrary.org/obo/chebi#is_enantiomer_of some '(S)-noradrenaline'</newAxiom>
<newAxiom>'(R)-noradrenaline' SubClassOf 'noradrenaline'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0086093</classIRI>
<classLabel>G protein-coupled acetylcholine receptor signaling pathway involved in heart process</classLabel>
<newAxiom>'G protein-coupled acetylcholine receptor signaling pathway involved in heart process' SubClassOf 'G protein-coupled receptor signaling pathway involved in heart process'</newAxiom>
<newAxiom>'G protein-coupled acetylcholine receptor signaling pathway involved in heart process' EquivalentTo 'G protein-coupled acetylcholine receptor signaling pathway' and ('part of' some 'heart process')</newAxiom>
<newAxiom>'G protein-coupled acetylcholine receptor signaling pathway involved in heart process' SubClassOf 'G protein-coupled acetylcholine receptor signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008509</classIRI>
<classLabel>anion transmembrane transporter activity</classLabel>
<newAxiom>'anion transmembrane transporter activity' SubClassOf 'has primary input' some 'anion'</newAxiom>
<newAxiom>'anion transmembrane transporter activity' SubClassOf 'part of' some 'anion transmembrane transport'</newAxiom>
<newAxiom>'anion transmembrane transporter activity' EquivalentTo 'transmembrane transporter activity' and ('has primary input' some 'anion')</newAxiom>
<newAxiom>'anion transmembrane transporter activity' SubClassOf 'ion transmembrane transporter activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008528</classIRI>
<classLabel>G protein-coupled peptide receptor activity</classLabel>
<newAxiom>'G protein-coupled peptide receptor activity' SubClassOf 'G protein-coupled receptor activity'</newAxiom>
<newAxiom>'G protein-coupled peptide receptor activity' SubClassOf 'peptide receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008527</classIRI>
<classLabel>taste receptor activity</classLabel>
<newAxiom>'taste receptor activity' SubClassOf 'transmembrane signaling receptor activity'</newAxiom>
<newAxiom>'taste receptor activity' SubClassOf 'part of' some 'detection of chemical stimulus involved in sensory perception of taste'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007210</classIRI>
<classLabel>serotonin receptor signaling pathway</classLabel>
<newAxiom>'serotonin receptor signaling pathway' SubClassOf 'signal transduction'</newAxiom>
<newAxiom>'serotonin receptor signaling pathway' EquivalentTo 'signal transduction' and ('starts with' some 'serotonin receptor activity')</newAxiom>
<newAxiom>'serotonin receptor signaling pathway' SubClassOf 'part of' some 'cellular response to dopamine'</newAxiom>
<newAxiom>'serotonin receptor signaling pathway' SubClassOf 'starts with' some 'serotonin receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007213</classIRI>
<classLabel>G protein-coupled acetylcholine receptor signaling pathway</classLabel>
<newAxiom>'G protein-coupled acetylcholine receptor signaling pathway' EquivalentTo 'signal transduction' and ('starts with' some 'G protein-coupled acetylcholine receptor activity')</newAxiom>
<newAxiom>'G protein-coupled acetylcholine receptor signaling pathway' SubClassOf 'acetylcholine receptor signaling pathway'</newAxiom>
<newAxiom>'G protein-coupled acetylcholine receptor signaling pathway' SubClassOf 'starts with' some 'G protein-coupled acetylcholine receptor activity'</newAxiom>
<newAxiom>'G protein-coupled acetylcholine receptor signaling pathway' SubClassOf 'G protein-coupled receptor signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007215</classIRI>
<classLabel>glutamate receptor signaling pathway</classLabel>
<newAxiom>'glutamate receptor signaling pathway' EquivalentTo 'signal transduction' and ('starts with' some 'glutamate receptor activity')</newAxiom>
<newAxiom>'glutamate receptor signaling pathway' SubClassOf 'cell surface receptor signaling pathway'</newAxiom>
<newAxiom>'glutamate receptor signaling pathway' SubClassOf 'starts with' some 'glutamate receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007216</classIRI>
<classLabel>G protein-coupled glutamate receptor signaling pathway</classLabel>
<newAxiom>'G protein-coupled glutamate receptor signaling pathway' SubClassOf 'G protein-coupled receptor signaling pathway'</newAxiom>
<newAxiom>'G protein-coupled glutamate receptor signaling pathway' SubClassOf 'starts with' some 'G protein-coupled glutamate receptor activity'</newAxiom>
<newAxiom>'G protein-coupled glutamate receptor signaling pathway' EquivalentTo 'signal transduction' and ('starts with' some 'G protein-coupled glutamate receptor activity')</newAxiom>
<newAxiom>'G protein-coupled glutamate receptor signaling pathway' SubClassOf 'glutamate receptor signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007218</classIRI>
<classLabel>neuropeptide signaling pathway</classLabel>
<newAxiom>'neuropeptide signaling pathway' SubClassOf not ('in taxon' some 'Fungi')</newAxiom>
<newAxiom>'neuropeptide signaling pathway' SubClassOf 'in taxon' some (not ('Fungi'))</newAxiom>
<newAxiom>'neuropeptide signaling pathway' SubClassOf 'G protein-coupled receptor signaling pathway'</newAxiom>
<newAxiom>'neuropeptide signaling pathway' DisjointWith 'in taxon' some 'Fungi'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003707</classIRI>
<classLabel>nuclear steroid receptor activity</classLabel>
<newAxiom>'nuclear steroid receptor activity' SubClassOf 'part of' some 'steroid hormone mediated signaling pathway'</newAxiom>
<newAxiom>'nuclear steroid receptor activity' SubClassOf 'signaling receptor activity'</newAxiom>
<newAxiom>'nuclear steroid receptor activity' EquivalentTo 'signaling receptor activity' and ('has input' some 'steroid hormone')</newAxiom>
<newAxiom>'nuclear steroid receptor activity' SubClassOf 'has input' some 'steroid hormone'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903179</classIRI>
<classLabel>regulation of dopamine biosynthetic process</classLabel>
<newAxiom>'regulation of dopamine biosynthetic process' SubClassOf 'regulates' some 'dopamine biosynthetic process'</newAxiom>
<newAxiom>'regulation of dopamine biosynthetic process' EquivalentTo 'biological regulation' and ('regulates' some 'dopamine biosynthetic process')</newAxiom>
<newAxiom>'regulation of dopamine biosynthetic process' SubClassOf 'regulation of biosynthetic process'</newAxiom>
<newAxiom>'regulation of dopamine biosynthetic process' SubClassOf 'regulation of dopamine metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903181</classIRI>
<classLabel>positive regulation of dopamine biosynthetic process</classLabel>
<newAxiom>'positive regulation of dopamine biosynthetic process' SubClassOf 'positive regulation of biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of dopamine biosynthetic process' SubClassOf 'positively regulates' some 'dopamine biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of dopamine biosynthetic process' SubClassOf 'positive regulation of dopamine metabolic process'</newAxiom>
<newAxiom>'positive regulation of dopamine biosynthetic process' SubClassOf 'regulation of dopamine biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of dopamine biosynthetic process' EquivalentTo 'biological regulation' and ('positively regulates' some 'dopamine biosynthetic process')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903180</classIRI>
<classLabel>negative regulation of dopamine biosynthetic process</classLabel>
<newAxiom>'negative regulation of dopamine biosynthetic process' SubClassOf 'regulation of dopamine biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of dopamine biosynthetic process' SubClassOf 'negative regulation of dopamine metabolic process'</newAxiom>
<newAxiom>'negative regulation of dopamine biosynthetic process' SubClassOf 'negative regulation of biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of dopamine biosynthetic process' SubClassOf 'negatively regulates' some 'dopamine biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of dopamine biosynthetic process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'dopamine biosynthetic process')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007167</classIRI>
<classLabel>enzyme-linked receptor protein signaling pathway</classLabel>
<newAxiom>'enzyme-linked receptor protein signaling pathway' SubClassOf 'cell surface receptor signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007169</classIRI>
<classLabel>transmembrane receptor protein tyrosine kinase signaling pathway</classLabel>
<newAxiom>'transmembrane receptor protein tyrosine kinase signaling pathway' SubClassOf 'enzyme-linked receptor protein signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_38147</classIRI>
<classLabel>cardiotonic drug</classLabel>
<newAxiom>'cardiotonic drug' SubClassOf 'cardiovascular drug'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007186</classIRI>
<classLabel>G protein-coupled receptor signaling pathway</classLabel>
<newAxiom>'G protein-coupled receptor signaling pathway' EquivalentTo 'signal transduction' and ('starts with' some 'G protein-coupled receptor activity')</newAxiom>
<newAxiom>'G protein-coupled receptor signaling pathway' SubClassOf 'signal transduction'</newAxiom>
<newAxiom>'G protein-coupled receptor signaling pathway' SubClassOf 'starts with' some 'G protein-coupled receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016907</classIRI>
<classLabel>G protein-coupled acetylcholine receptor activity</classLabel>
<newAxiom>'G protein-coupled acetylcholine receptor activity' SubClassOf 'acetylcholine receptor activity'</newAxiom>
<newAxiom>'G protein-coupled acetylcholine receptor activity' SubClassOf 'G protein-coupled amine receptor activity'</newAxiom>
<newAxiom>'G protein-coupled acetylcholine receptor activity' EquivalentTo 'G protein-coupled receptor activity' and ('has input' some 'acetylcholine')</newAxiom>
<newAxiom>'G protein-coupled acetylcholine receptor activity' SubClassOf 'G protein-coupled neurotransmitter receptor activity'</newAxiom>
<newAxiom>'G protein-coupled acetylcholine receptor activity' SubClassOf 'part of' some 'G protein-coupled acetylcholine receptor signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004930</classIRI>
<classLabel>G protein-coupled receptor activity</classLabel>
<newAxiom>'G protein-coupled receptor activity' SubClassOf 'transmembrane signaling receptor activity'</newAxiom>
<newAxiom>'G protein-coupled receptor activity' SubClassOf 'part of' some 'G protein-coupled receptor signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019199</classIRI>
<classLabel>transmembrane receptor protein kinase activity</classLabel>
<newAxiom>'transmembrane receptor protein kinase activity' SubClassOf 'protein kinase activity'</newAxiom>
<newAxiom>'transmembrane receptor protein kinase activity' SubClassOf 'transmembrane signaling receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033483</classIRI>
<classLabel>gas homeostasis</classLabel>
<newAxiom>'gas homeostasis' SubClassOf 'chemical homeostasis'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004967</classIRI>
<classLabel>glucagon receptor activity</classLabel>
<newAxiom>'glucagon receptor activity' SubClassOf 'part of' some 'cellular response to glucagon stimulus'</newAxiom>
<newAxiom>'glucagon receptor activity' SubClassOf 'has input' some 'glucagon'</newAxiom>
<newAxiom>'glucagon receptor activity' EquivalentTo 'signaling receptor activity' and ('has input' some 'glucagon')</newAxiom>
<newAxiom>'glucagon receptor activity' SubClassOf 'G protein-coupled peptide receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004993</classIRI>
<classLabel>G protein-coupled serotonin receptor activity</classLabel>
<newAxiom>'G protein-coupled serotonin receptor activity' SubClassOf 'serotonin receptor activity'</newAxiom>
<newAxiom>'G protein-coupled serotonin receptor activity' EquivalentTo 'G protein-coupled amine receptor activity' and ('has input' some 'serotonin(1+)')</newAxiom>
<newAxiom>'G protein-coupled serotonin receptor activity' SubClassOf 'G protein-coupled amine receptor activity'</newAxiom>
<newAxiom>'G protein-coupled serotonin receptor activity' SubClassOf 'part of' some 'G protein-coupled serotonin receptor signaling pathway'</newAxiom>
<newAxiom>'G protein-coupled serotonin receptor activity' SubClassOf 'has_part' some 'serotonin binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004994</classIRI>
<classLabel>somatostatin receptor activity</classLabel>
<newAxiom>'somatostatin receptor activity' SubClassOf 'has input' some 'somatostatin'</newAxiom>
<newAxiom>'somatostatin receptor activity' EquivalentTo 'signaling receptor activity' and ('has input' some 'somatostatin')</newAxiom>
<newAxiom>'somatostatin receptor activity' SubClassOf 'part of' some 'somatostatin signaling pathway'</newAxiom>
<newAxiom>'somatostatin receptor activity' SubClassOf 'neuropeptide receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009755</classIRI>
<classLabel>hormone-mediated signaling pathway</classLabel>
<newAxiom>'hormone-mediated signaling pathway' SubClassOf 'part of' some 'cellular response to hormone stimulus'</newAxiom>
<newAxiom>'hormone-mediated signaling pathway' SubClassOf 'signal transduction'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_59905</classIRI>
<classLabel>dopaminium(1+)</classLabel>
<newAxiom>'dopaminium(1+)' SubClassOf 'has role' some 'human metabolite'</newAxiom>
<newAxiom>'dopaminium(1+)' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of some 'dopamine'</newAxiom>
<newAxiom>'dopaminium(1+)' SubClassOf 'ammonium ion derivative'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046627</classIRI>
<classLabel>negative regulation of insulin receptor signaling pathway</classLabel>
<newAxiom>'negative regulation of insulin receptor signaling pathway' SubClassOf 'regulation of insulin receptor signaling pathway'</newAxiom>
<newAxiom>'negative regulation of insulin receptor signaling pathway' SubClassOf 'negative regulation of signal transduction'</newAxiom>
<newAxiom>'negative regulation of insulin receptor signaling pathway' SubClassOf 'negative regulation of cellular response to insulin stimulus'</newAxiom>
<newAxiom>'negative regulation of insulin receptor signaling pathway' EquivalentTo 'biological regulation' and ('negatively regulates' some 'insulin receptor signaling pathway')</newAxiom>
<newAxiom>'negative regulation of insulin receptor signaling pathway' SubClassOf 'negatively regulates' some 'insulin receptor signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046626</classIRI>
<classLabel>regulation of insulin receptor signaling pathway</classLabel>
<newAxiom>'regulation of insulin receptor signaling pathway' SubClassOf 'regulation of signal transduction'</newAxiom>
<newAxiom>'regulation of insulin receptor signaling pathway' SubClassOf 'regulates' some 'insulin receptor signaling pathway'</newAxiom>
<newAxiom>'regulation of insulin receptor signaling pathway' EquivalentTo 'biological regulation' and ('regulates' some 'insulin receptor signaling pathway')</newAxiom>
<newAxiom>'regulation of insulin receptor signaling pathway' SubClassOf 'in taxon' only 'Eumetazoa'</newAxiom>
<newAxiom>'regulation of insulin receptor signaling pathway' SubClassOf 'only in taxon' some 'Eumetazoa'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046628</classIRI>
<classLabel>positive regulation of insulin receptor signaling pathway</classLabel>
<newAxiom>'positive regulation of insulin receptor signaling pathway' SubClassOf 'regulation of insulin receptor signaling pathway'</newAxiom>
<newAxiom>'positive regulation of insulin receptor signaling pathway' SubClassOf 'positively regulates' some 'insulin receptor signaling pathway'</newAxiom>
<newAxiom>'positive regulation of insulin receptor signaling pathway' SubClassOf 'positive regulation of cellular response to insulin stimulus'</newAxiom>
<newAxiom>'positive regulation of insulin receptor signaling pathway' EquivalentTo 'biological regulation' and ('positively regulates' some 'insulin receptor signaling pathway')</newAxiom>
<newAxiom>'positive regulation of insulin receptor signaling pathway' SubClassOf 'positive regulation of signal transduction'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099145</classIRI>
<classLabel>regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane</classLabel>
<newAxiom>'regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane' SubClassOf 'regulation of receptor localization to synapse'</newAxiom>
<newAxiom>'regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane' EquivalentTo 'biological regulation' and ('regulates' some 'exocytic insertion of neurotransmitter receptor to postsynaptic membrane')</newAxiom>
<newAxiom>'regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane' SubClassOf 'regulation of protein transport'</newAxiom>
<newAxiom>'regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane' SubClassOf 'regulation of protein localization to membrane'</newAxiom>
<newAxiom>'regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane' SubClassOf 'regulation of protein localization to cell periphery'</newAxiom>
<newAxiom>'regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane' SubClassOf 'regulates' some 'exocytic insertion of neurotransmitter receptor to postsynaptic membrane'</newAxiom>
<newAxiom>'regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane' SubClassOf 'regulation of exocytosis'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004860</classIRI>
<classLabel>protein kinase inhibitor activity</classLabel>
<newAxiom>'protein kinase inhibitor activity' SubClassOf 'negatively regulates' some 'protein kinase activity'</newAxiom>
<newAxiom>'protein kinase inhibitor activity' SubClassOf 'kinase inhibitor activity'</newAxiom>
<newAxiom>'protein kinase inhibitor activity' EquivalentTo 'molecular function inhibitor activity' and ('negatively regulates' some 'protein kinase activity')</newAxiom>
<newAxiom>'protein kinase inhibitor activity' SubClassOf 'protein kinase regulator activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044070</classIRI>
<classLabel>regulation of anion transport</classLabel>
<newAxiom>'regulation of anion transport' SubClassOf 'regulation of ion transport'</newAxiom>
<newAxiom>'regulation of anion transport' SubClassOf 'regulates' some 'anion transport'</newAxiom>
<newAxiom>'regulation of anion transport' EquivalentTo 'biological regulation' and ('regulates' some 'anion transport')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004888</classIRI>
<classLabel>transmembrane signaling receptor activity</classLabel>
<newAxiom>'transmembrane signaling receptor activity' SubClassOf 'signaling receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015464</classIRI>
<classLabel>acetylcholine receptor activity</classLabel>
<newAxiom>'acetylcholine receptor activity' EquivalentTo 'signaling receptor activity' and ('has input' some 'acetylcholine')</newAxiom>
<newAxiom>'acetylcholine receptor activity' SubClassOf 'part of' some 'synaptic transmission, cholinergic'</newAxiom>
<newAxiom>'acetylcholine receptor activity' SubClassOf 'postsynaptic neurotransmitter receptor activity'</newAxiom>
<newAxiom>'acetylcholine receptor activity' SubClassOf 'transmembrane signaling receptor activity'</newAxiom>
<newAxiom>'acetylcholine receptor activity' SubClassOf 'has_part' some 'acetylcholine binding'</newAxiom>
<newAxiom>'acetylcholine receptor activity' SubClassOf 'has input' some 'acetylcholine'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903350</classIRI>
<classLabel>response to dopamine</classLabel>
<newAxiom>'response to dopamine' SubClassOf 'response to nitrogen compound'</newAxiom>
<newAxiom>'response to dopamine' SubClassOf 'has input' some 'dopaminium(1+)'</newAxiom>
<newAxiom>'response to dopamine' EquivalentTo 'response to stimulus' and ('has input' some 'dopaminium(1+)')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903351</classIRI>
<classLabel>cellular response to dopamine</classLabel>
<newAxiom>'cellular response to dopamine' SubClassOf 'cellular response to nitrogen compound'</newAxiom>
<newAxiom>'cellular response to dopamine' EquivalentTo 'cellular response to chemical stimulus' and ('has input' some 'dopaminium(1+)')</newAxiom>
<newAxiom>'cellular response to dopamine' SubClassOf 'response to dopamine'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038169</classIRI>
<classLabel>somatostatin receptor signaling pathway</classLabel>
<newAxiom>'somatostatin receptor signaling pathway' SubClassOf 'G protein-coupled receptor signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038187</classIRI>
<classLabel>pattern recognition receptor activity</classLabel>
<newAxiom>'pattern recognition receptor activity' SubClassOf 'signaling receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038170</classIRI>
<classLabel>somatostatin signaling pathway</classLabel>
<newAxiom>'somatostatin signaling pathway' SubClassOf 'has input' some 'somatostatin'</newAxiom>
<newAxiom>'somatostatin signaling pathway' SubClassOf 'somatostatin receptor signaling pathway'</newAxiom>
<newAxiom>'somatostatin signaling pathway' SubClassOf 'hormone-mediated signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099124</classIRI>
<classLabel>axonal dopamine secretion</classLabel>
<newAxiom>'axonal dopamine secretion' SubClassOf 'dopamine secretion'</newAxiom>
<newAxiom>'axonal dopamine secretion' SubClassOf 'occurs in' some 'axon'</newAxiom>
<newAxiom>'axonal dopamine secretion' EquivalentTo 'dopamine secretion' and ('occurs in' some 'axon')</newAxiom>
<newAxiom>'axonal dopamine secretion' SubClassOf 'establishment of localization in cell'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099123</classIRI>
<classLabel>somato-dendritic dopamine secretion</classLabel>
<newAxiom>'somato-dendritic dopamine secretion' SubClassOf 'dopamine secretion'</newAxiom>
<newAxiom>'somato-dendritic dopamine secretion' SubClassOf 'occurs in' some 'somatodendritic compartment'</newAxiom>
<newAxiom>'somato-dendritic dopamine secretion' SubClassOf 'establishment of localization in cell'</newAxiom>
<newAxiom>'somato-dendritic dopamine secretion' EquivalentTo 'dopamine secretion' and ('occurs in' some 'somatodendritic compartment')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099072</classIRI>
<classLabel>regulation of postsynaptic membrane neurotransmitter receptor levels</classLabel>
<newAxiom>'regulation of postsynaptic membrane neurotransmitter receptor levels' SubClassOf 'regulation of biological quality'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045211</classIRI>
<classLabel>postsynaptic membrane</classLabel>
<newAxiom>'postsynaptic membrane' SubClassOf 'part of' some 'postsynapse'</newAxiom>
<newAxiom>'postsynaptic membrane' SubClassOf 'synaptic membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008277</classIRI>
<classLabel>regulation of G protein-coupled receptor signaling pathway</classLabel>
<newAxiom>'regulation of G protein-coupled receptor signaling pathway' SubClassOf 'regulates' some 'G protein-coupled receptor signaling pathway'</newAxiom>
<newAxiom>'regulation of G protein-coupled receptor signaling pathway' SubClassOf 'regulation of signal transduction'</newAxiom>
<newAxiom>'regulation of G protein-coupled receptor signaling pathway' EquivalentTo 'biological regulation' and ('regulates' some 'G protein-coupled receptor signaling pathway')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008286</classIRI>
<classLabel>insulin receptor signaling pathway</classLabel>
<newAxiom>'insulin receptor signaling pathway' SubClassOf 'part of' some 'cellular response to insulin stimulus'</newAxiom>
<newAxiom>'insulin receptor signaling pathway' SubClassOf 'only in taxon' some 'Eumetazoa'</newAxiom>
<newAxiom>'insulin receptor signaling pathway' SubClassOf 'transmembrane receptor protein tyrosine kinase signaling pathway'</newAxiom>
<newAxiom>'insulin receptor signaling pathway' SubClassOf 'in taxon' only 'Eumetazoa'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004713</classIRI>
<classLabel>protein tyrosine kinase activity</classLabel>
<newAxiom>'protein tyrosine kinase activity' SubClassOf 'protein kinase activity'</newAxiom>
<newAxiom>'protein tyrosine kinase activity' SubClassOf 'part of' some 'peptidyl-tyrosine phosphorylation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004714</classIRI>
<classLabel>transmembrane receptor protein tyrosine kinase activity</classLabel>
<newAxiom>'transmembrane receptor protein tyrosine kinase activity' SubClassOf 'transmembrane receptor protein kinase activity'</newAxiom>
<newAxiom>'transmembrane receptor protein tyrosine kinase activity' SubClassOf 'protein tyrosine kinase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0095500</classIRI>
<classLabel>acetylcholine receptor signaling pathway</classLabel>
<newAxiom>'acetylcholine receptor signaling pathway' SubClassOf 'postsynaptic signal transduction'</newAxiom>
<newAxiom>'acetylcholine receptor signaling pathway' SubClassOf 'starts with' some 'acetylcholine receptor activity'</newAxiom>
<newAxiom>'acetylcholine receptor signaling pathway' SubClassOf 'part of' some 'cellular response to acetylcholine'</newAxiom>
<newAxiom>'acetylcholine receptor signaling pathway' EquivalentTo 'signal transduction' and ('starts with' some 'acetylcholine receptor activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016773</classIRI>
<classLabel>phosphotransferase activity, alcohol group as acceptor</classLabel>
<newAxiom>'phosphotransferase activity, alcohol group as acceptor' SubClassOf 'transferase activity, transferring phosphorus-containing groups'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014046</classIRI>
<classLabel>dopamine secretion</classLabel>
<newAxiom>'dopamine secretion' SubClassOf 'dopamine transport'</newAxiom>
<newAxiom>'dopamine secretion' EquivalentTo 'secretion' and ('has primary input' some 'dopaminium(1+)')</newAxiom>
<newAxiom>'dopamine secretion' SubClassOf 'signal release'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014059</classIRI>
<classLabel>regulation of dopamine secretion</classLabel>
<newAxiom>'regulation of dopamine secretion' SubClassOf 'regulates' some 'dopamine secretion'</newAxiom>
<newAxiom>'regulation of dopamine secretion' SubClassOf 'regulation of secretion by cell'</newAxiom>
<newAxiom>'regulation of dopamine secretion' SubClassOf 'regulation of ion transport'</newAxiom>
<newAxiom>'regulation of dopamine secretion' EquivalentTo 'biological regulation' and ('regulates' some 'dopamine secretion')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038023</classIRI>
<classLabel>signaling receptor activity</classLabel>
<newAxiom>'signaling receptor activity' SubClassOf 'molecular transducer activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008227</classIRI>
<classLabel>G protein-coupled amine receptor activity</classLabel>
<newAxiom>'G protein-coupled amine receptor activity' SubClassOf 'has input' some 'amine'</newAxiom>
<newAxiom>'G protein-coupled amine receptor activity' EquivalentTo 'G protein-coupled receptor activity' and ('has input' some 'amine')</newAxiom>
<newAxiom>'G protein-coupled amine receptor activity' SubClassOf 'G protein-coupled receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010469</classIRI>
<classLabel>regulation of signaling receptor activity</classLabel>
<newAxiom>'regulation of signaling receptor activity' SubClassOf 'regulates' some 'signaling receptor activity'</newAxiom>
<newAxiom>'regulation of signaling receptor activity' SubClassOf 'regulation of molecular function'</newAxiom>
<newAxiom>'regulation of signaling receptor activity' EquivalentTo 'biological regulation' and ('regulates' some 'signaling receptor activity')</newAxiom>
<newAxiom>'regulation of signaling receptor activity' SubClassOf 'regulation of signal transduction'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008188</classIRI>
<classLabel>neuropeptide receptor activity</classLabel>
<newAxiom>'neuropeptide receptor activity' SubClassOf 'part of' some 'neuropeptide signaling pathway'</newAxiom>
<newAxiom>'neuropeptide receptor activity' SubClassOf 'has_part' some 'neuropeptide binding'</newAxiom>
<newAxiom>'neuropeptide receptor activity' SubClassOf not ('in taxon' some 'Fungi')</newAxiom>
<newAxiom>'neuropeptide receptor activity' DisjointWith 'in taxon' some 'Fungi'</newAxiom>
<newAxiom>'neuropeptide receptor activity' SubClassOf 'in taxon' some (not ('Fungi'))</newAxiom>
<newAxiom>'neuropeptide receptor activity' SubClassOf 'G protein-coupled peptide receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004672</classIRI>
<classLabel>protein kinase activity</classLabel>
<newAxiom>'protein kinase activity' SubClassOf 'phosphotransferase activity, alcohol group as acceptor'</newAxiom>
<newAxiom>'protein kinase activity' SubClassOf 'catalytic activity, acting on a protein'</newAxiom>
<newAxiom>'protein kinase activity' SubClassOf 'kinase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042923</classIRI>
<classLabel>neuropeptide binding</classLabel>
<newAxiom>'neuropeptide binding' SubClassOf 'peptide binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903539</classIRI>
<classLabel>protein localization to postsynaptic membrane</classLabel>
<newAxiom>'protein localization to postsynaptic membrane' SubClassOf 'protein localization to membrane'</newAxiom>
<newAxiom>'protein localization to postsynaptic membrane' SubClassOf 'protein localization to cell periphery'</newAxiom>
<newAxiom>'protein localization to postsynaptic membrane' SubClassOf 'protein localization to postsynapse'</newAxiom>
<newAxiom>'protein localization to postsynaptic membrane' EquivalentTo 'protein localization' and ('has target end location' some 'postsynaptic membrane')</newAxiom>
<newAxiom>'protein localization to postsynaptic membrane' SubClassOf 'has target end location' some 'postsynaptic membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903540</classIRI>
<classLabel>establishment of protein localization to postsynaptic membrane</classLabel>
<newAxiom>'establishment of protein localization to postsynaptic membrane' SubClassOf 'establishment of protein localization to membrane'</newAxiom>
<newAxiom>'establishment of protein localization to postsynaptic membrane' SubClassOf 'protein localization to postsynaptic membrane'</newAxiom>
<newAxiom>'establishment of protein localization to postsynaptic membrane' EquivalentTo 'establishment of protein localization' and ('has target end location' some 'postsynaptic membrane')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008066</classIRI>
<classLabel>glutamate receptor activity</classLabel>
<newAxiom>'glutamate receptor activity' EquivalentTo 'signaling receptor activity' and ('has input' some 'glutamate(1-)')</newAxiom>
<newAxiom>'glutamate receptor activity' SubClassOf 'transmembrane signaling receptor activity'</newAxiom>
<newAxiom>'glutamate receptor activity' SubClassOf 'has input' some 'glutamate(1-)'</newAxiom>
<newAxiom>'glutamate receptor activity' SubClassOf 'has_part' some 'glutamate binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090494</classIRI>
<classLabel>dopamine uptake</classLabel>
<newAxiom>'dopamine uptake' EquivalentTo 'transport' and ('has target start location' some 'extracellular region') and ('has target end location' some 'intracellular anatomical structure') and ('has primary input' some 'dopaminium(1+)')</newAxiom>
<newAxiom>'dopamine uptake' SubClassOf 'import into cell'</newAxiom>
<newAxiom>'dopamine uptake' SubClassOf 'dopamine transport'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016500</classIRI>
<classLabel>protein-hormone receptor activity</classLabel>
<newAxiom>'protein-hormone receptor activity' SubClassOf 'signaling receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903768</classIRI>
<classLabel>taste receptor complex</classLabel>
<newAxiom>'taste receptor complex' SubClassOf 'capable of' some 'taste receptor activity'</newAxiom>
<newAxiom>'taste receptor complex' SubClassOf 'receptor complex'</newAxiom>
<newAxiom>'taste receptor complex' EquivalentTo 'protein-containing complex' and ('capable of' some 'taste receptor activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005899</classIRI>
<classLabel>insulin receptor complex</classLabel>
<newAxiom>'insulin receptor complex' SubClassOf 'only in taxon' some 'Eumetazoa'</newAxiom>
<newAxiom>'insulin receptor complex' SubClassOf 'in taxon' only 'Eumetazoa'</newAxiom>
<newAxiom>'insulin receptor complex' SubClassOf 'plasma membrane signaling receptor complex'</newAxiom>
<newAxiom>'insulin receptor complex' EquivalentTo 'protein-containing complex' and ('capable of' some 'insulin receptor activity')</newAxiom>
<newAxiom>'insulin receptor complex' SubClassOf 'capable of' some 'insulin receptor activity'</newAxiom>
<newAxiom>'insulin receptor complex' SubClassOf 'protein kinase complex'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_35522</classIRI>
<classLabel>beta-adrenergic agonist</classLabel>
<newAxiom>'beta-adrenergic agonist' SubClassOf 'beta-adrenergic drug'</newAxiom>
<newAxiom>'beta-adrenergic agonist' SubClassOf 'adrenergic agonist'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048875</classIRI>
<classLabel>chemical homeostasis within a tissue</classLabel>
<newAxiom>'chemical homeostasis within a tissue' SubClassOf 'chemical homeostasis'</newAxiom>
<newAxiom>'chemical homeostasis within a tissue' SubClassOf 'tissue homeostasis'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072501</classIRI>
<classLabel>cellular divalent inorganic anion homeostasis</classLabel>
<newAxiom>'cellular divalent inorganic anion homeostasis' SubClassOf 'divalent inorganic anion homeostasis'</newAxiom>
<newAxiom>'cellular divalent inorganic anion homeostasis' SubClassOf 'cellular anion homeostasis'</newAxiom>
<newAxiom>'cellular divalent inorganic anion homeostasis' EquivalentTo 'cellular homeostasis' and ('regulates levels of' some 'divalent inorganic anion')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072502</classIRI>
<classLabel>cellular trivalent inorganic anion homeostasis</classLabel>
<newAxiom>'cellular trivalent inorganic anion homeostasis' SubClassOf 'cellular anion homeostasis'</newAxiom>
<newAxiom>'cellular trivalent inorganic anion homeostasis' SubClassOf 'trivalent inorganic anion homeostasis'</newAxiom>
<newAxiom>'cellular trivalent inorganic anion homeostasis' EquivalentTo 'cellular homeostasis' and ('regulates levels of' some 'trivalent inorganic anion')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072505</classIRI>
<classLabel>divalent inorganic anion homeostasis</classLabel>
<newAxiom>'divalent inorganic anion homeostasis' EquivalentTo 'chemical homeostasis' and ('regulates levels of' some 'divalent inorganic anion')</newAxiom>
<newAxiom>'divalent inorganic anion homeostasis' SubClassOf 'anion homeostasis'</newAxiom>
<newAxiom>'divalent inorganic anion homeostasis' SubClassOf 'inorganic ion homeostasis'</newAxiom>
<newAxiom>'divalent inorganic anion homeostasis' SubClassOf 'regulates levels of' some 'divalent inorganic anion'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072506</classIRI>
<classLabel>trivalent inorganic anion homeostasis</classLabel>
<newAxiom>'trivalent inorganic anion homeostasis' SubClassOf 'inorganic ion homeostasis'</newAxiom>
<newAxiom>'trivalent inorganic anion homeostasis' EquivalentTo 'chemical homeostasis' and ('regulates levels of' some 'trivalent inorganic anion')</newAxiom>
<newAxiom>'trivalent inorganic anion homeostasis' SubClassOf 'regulates levels of' some 'trivalent inorganic anion'</newAxiom>
<newAxiom>'trivalent inorganic anion homeostasis' SubClassOf 'anion homeostasis'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903792</classIRI>
<classLabel>negative regulation of anion transport</classLabel>
<newAxiom>'negative regulation of anion transport' SubClassOf 'negatively regulates' some 'anion transport'</newAxiom>
<newAxiom>'negative regulation of anion transport' EquivalentTo 'biological regulation' and ('negatively regulates' some 'anion transport')</newAxiom>
<newAxiom>'negative regulation of anion transport' SubClassOf 'negative regulation of ion transport'</newAxiom>
<newAxiom>'negative regulation of anion transport' SubClassOf 'regulation of anion transport'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903793</classIRI>
<classLabel>positive regulation of anion transport</classLabel>
<newAxiom>'positive regulation of anion transport' SubClassOf 'positive regulation of ion transport'</newAxiom>
<newAxiom>'positive regulation of anion transport' SubClassOf 'positively regulates' some 'anion transport'</newAxiom>
<newAxiom>'positive regulation of anion transport' SubClassOf 'regulation of anion transport'</newAxiom>
<newAxiom>'positive regulation of anion transport' EquivalentTo 'biological regulation' and ('positively regulates' some 'anion transport')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/PR_000030035</classIRI>
<classLabel>G-protein coupled receptor</classLabel>
<newAxiom>'G-protein coupled receptor' SubClassOf 'protein'</newAxiom>
<newAxiom>'G-protein coupled receptor' EquivalentTo 'protein' and ('capable of' some 'G protein-coupled receptor activity')</newAxiom>
<newAxiom>'G-protein coupled receptor' SubClassOf 'capable of' some 'G protein-coupled receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903959</classIRI>
<classLabel>regulation of anion transmembrane transport</classLabel>
<newAxiom>'regulation of anion transmembrane transport' SubClassOf 'regulates' some 'anion transmembrane transport'</newAxiom>
<newAxiom>'regulation of anion transmembrane transport' EquivalentTo 'biological regulation' and ('regulates' some 'anion transmembrane transport')</newAxiom>
<newAxiom>'regulation of anion transmembrane transport' SubClassOf 'regulation of ion transmembrane transport'</newAxiom>
<newAxiom>'regulation of anion transmembrane transport' SubClassOf 'regulation of anion transport'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903961</classIRI>
<classLabel>positive regulation of anion transmembrane transport</classLabel>
<newAxiom>'positive regulation of anion transmembrane transport' SubClassOf 'positively regulates' some 'anion transmembrane transport'</newAxiom>
<newAxiom>'positive regulation of anion transmembrane transport' EquivalentTo 'biological regulation' and ('positively regulates' some 'anion transmembrane transport')</newAxiom>
<newAxiom>'positive regulation of anion transmembrane transport' SubClassOf 'positive regulation of ion transmembrane transport'</newAxiom>
<newAxiom>'positive regulation of anion transmembrane transport' SubClassOf 'positive regulation of anion transport'</newAxiom>
<newAxiom>'positive regulation of anion transmembrane transport' SubClassOf 'regulation of anion transmembrane transport'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903960</classIRI>
<classLabel>negative regulation of anion transmembrane transport</classLabel>
<newAxiom>'negative regulation of anion transmembrane transport' EquivalentTo 'biological regulation' and ('negatively regulates' some 'anion transmembrane transport')</newAxiom>
<newAxiom>'negative regulation of anion transmembrane transport' SubClassOf 'negative regulation of ion transmembrane transport'</newAxiom>
<newAxiom>'negative regulation of anion transmembrane transport' SubClassOf 'negatively regulates' some 'anion transmembrane transport'</newAxiom>
<newAxiom>'negative regulation of anion transmembrane transport' SubClassOf 'negative regulation of anion transport'</newAxiom>
<newAxiom>'negative regulation of anion transmembrane transport' SubClassOf 'regulation of anion transmembrane transport'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098962</classIRI>
<classLabel>regulation of postsynaptic neurotransmitter receptor activity</classLabel>
<newAxiom>'regulation of postsynaptic neurotransmitter receptor activity' EquivalentTo 'regulation of molecular function' and ('regulates' some 'postsynaptic neurotransmitter receptor activity')</newAxiom>
<newAxiom>'regulation of postsynaptic neurotransmitter receptor activity' SubClassOf 'regulates' some 'postsynaptic neurotransmitter receptor activity'</newAxiom>
<newAxiom>'regulation of postsynaptic neurotransmitter receptor activity' SubClassOf 'regulation of nervous system process'</newAxiom>
<newAxiom>'regulation of postsynaptic neurotransmitter receptor activity' SubClassOf 'modulation of chemical synaptic transmission'</newAxiom>
<newAxiom>'regulation of postsynaptic neurotransmitter receptor activity' SubClassOf 'regulation of neurotransmitter receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098967</classIRI>
<classLabel>exocytic insertion of neurotransmitter receptor to postsynaptic membrane</classLabel>
<newAxiom>'exocytic insertion of neurotransmitter receptor to postsynaptic membrane' SubClassOf 'part of' some 'neurotransmitter receptor transport to postsynaptic membrane'</newAxiom>
<newAxiom>'exocytic insertion of neurotransmitter receptor to postsynaptic membrane' EquivalentTo 'exocytosis' and ('part of' some 'neurotransmitter receptor transport to postsynaptic membrane')</newAxiom>
<newAxiom>'exocytic insertion of neurotransmitter receptor to postsynaptic membrane' SubClassOf 'regulation of postsynaptic membrane neurotransmitter receptor levels'</newAxiom>
<newAxiom>'exocytic insertion of neurotransmitter receptor to postsynaptic membrane' SubClassOf 'exocytosis'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098969</classIRI>
<classLabel>neurotransmitter receptor transport to postsynaptic membrane</classLabel>
<newAxiom>'neurotransmitter receptor transport to postsynaptic membrane' SubClassOf 'establishment of protein localization to postsynaptic membrane'</newAxiom>
<newAxiom>'neurotransmitter receptor transport to postsynaptic membrane' SubClassOf 'receptor localization to synapse'</newAxiom>
<newAxiom>'neurotransmitter receptor transport to postsynaptic membrane' SubClassOf 'neurotransmitter receptor transport to plasma membrane'</newAxiom>
<newAxiom>'neurotransmitter receptor transport to postsynaptic membrane' EquivalentTo 'protein transport' and ('has target end location' some 'postsynaptic membrane') and ('has primary input' some 'neurotransmitter receptor complex')</newAxiom>
<newAxiom>'neurotransmitter receptor transport to postsynaptic membrane' SubClassOf 'regulation of postsynaptic membrane neurotransmitter receptor levels'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098971</classIRI>
<classLabel>anterograde dendritic transport of neurotransmitter receptor complex</classLabel>
<newAxiom>'anterograde dendritic transport of neurotransmitter receptor complex' SubClassOf 'anterograde dendritic transport'</newAxiom>
<newAxiom>'anterograde dendritic transport of neurotransmitter receptor complex' EquivalentTo 'transport' and ('occurs in' some 'dendrite cytoplasm') and ('has target end location' some 'postsynapse') and ('results in transport along' some 'microtubule') and ('has primary input' some 'neurotransmitter receptor complex')</newAxiom>
<newAxiom>'anterograde dendritic transport of neurotransmitter receptor complex' SubClassOf 'has primary input' some 'neurotransmitter receptor complex'</newAxiom>
<newAxiom>'anterograde dendritic transport of neurotransmitter receptor complex' SubClassOf 'receptor localization to synapse'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098988</classIRI>
<classLabel>G protein-coupled glutamate receptor activity</classLabel>
<newAxiom>'G protein-coupled glutamate receptor activity' SubClassOf 'G protein-coupled receptor activity'</newAxiom>
<newAxiom>'G protein-coupled glutamate receptor activity' EquivalentTo 'G protein-coupled receptor activity' and ('has input' some 'glutamate(1-)')</newAxiom>
<newAxiom>'G protein-coupled glutamate receptor activity' SubClassOf 'glutamate receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030545</classIRI>
<classLabel>signaling receptor regulator activity</classLabel>
<newAxiom>'signaling receptor regulator activity' EquivalentTo 'molecular function regulator activity' and ('regulates' some 'signaling receptor activity')</newAxiom>
<newAxiom>'signaling receptor regulator activity' SubClassOf 'molecular function regulator activity'</newAxiom>
<newAxiom>'signaling receptor regulator activity' SubClassOf 'regulates' some 'signaling receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030546</classIRI>
<classLabel>signaling receptor activator activity</classLabel>
<newAxiom>'signaling receptor activator activity' EquivalentTo 'molecular function activator activity' and ('positively regulates' some 'signaling receptor activity')</newAxiom>
<newAxiom>'signaling receptor activator activity' SubClassOf 'positively regulates' some 'signaling receptor activity'</newAxiom>
<newAxiom>'signaling receptor activator activity' SubClassOf 'molecular function activator activity'</newAxiom>
<newAxiom>'signaling receptor activator activity' SubClassOf 'signaling receptor regulator activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030547</classIRI>
<classLabel>signaling receptor inhibitor activity</classLabel>
<newAxiom>'signaling receptor inhibitor activity' EquivalentTo 'molecular function regulator activity' and ('negatively regulates' some 'signaling receptor activity')</newAxiom>
<newAxiom>'signaling receptor inhibitor activity' SubClassOf 'part of' some 'negative regulation of signaling receptor activity'</newAxiom>
<newAxiom>'signaling receptor inhibitor activity' SubClassOf 'negatively regulates' some 'signaling receptor activity'</newAxiom>
<newAxiom>'signaling receptor inhibitor activity' SubClassOf 'signaling receptor regulator activity'</newAxiom>
<newAxiom>'signaling receptor inhibitor activity' SubClassOf 'molecular function inhibitor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030548</classIRI>
<classLabel>acetylcholine receptor regulator activity</classLabel>
<newAxiom>'acetylcholine receptor regulator activity' EquivalentTo 'molecular function regulator activity' and ('regulates' some 'acetylcholine receptor activity')</newAxiom>
<newAxiom>'acetylcholine receptor regulator activity' SubClassOf 'neurotransmitter receptor regulator activity'</newAxiom>
<newAxiom>'acetylcholine receptor regulator activity' SubClassOf 'regulates' some 'acetylcholine receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030549</classIRI>
<classLabel>acetylcholine receptor activator activity</classLabel>
<newAxiom>'acetylcholine receptor activator activity' SubClassOf 'acetylcholine receptor regulator activity'</newAxiom>
<newAxiom>'acetylcholine receptor activator activity' SubClassOf 'positively regulates' some 'acetylcholine receptor activity'</newAxiom>
<newAxiom>'acetylcholine receptor activator activity' SubClassOf 'signaling receptor activator activity'</newAxiom>
<newAxiom>'acetylcholine receptor activator activity' EquivalentTo 'molecular function activator activity' and ('positively regulates' some 'acetylcholine receptor activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030550</classIRI>
<classLabel>acetylcholine receptor inhibitor activity</classLabel>
<newAxiom>'acetylcholine receptor inhibitor activity' SubClassOf 'negatively regulates' some 'acetylcholine receptor activity'</newAxiom>
<newAxiom>'acetylcholine receptor inhibitor activity' SubClassOf 'signaling receptor inhibitor activity'</newAxiom>
<newAxiom>'acetylcholine receptor inhibitor activity' SubClassOf 'acetylcholine receptor regulator activity'</newAxiom>
<newAxiom>'acetylcholine receptor inhibitor activity' EquivalentTo 'molecular function regulator activity' and ('negatively regulates' some 'acetylcholine receptor activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030594</classIRI>
<classLabel>neurotransmitter receptor activity</classLabel>
<newAxiom>'neurotransmitter receptor activity' SubClassOf 'signaling receptor activity'</newAxiom>
<newAxiom>'neurotransmitter receptor activity' SubClassOf 'has_part' some 'neurotransmitter binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001941</classIRI>
<classLabel>postsynaptic membrane organization</classLabel>
<newAxiom>'postsynaptic membrane organization' SubClassOf 'results in organization of' some 'postsynaptic membrane'</newAxiom>
<newAxiom>'postsynaptic membrane organization' SubClassOf 'membrane organization'</newAxiom>
<newAxiom>'postsynaptic membrane organization' SubClassOf 'part of' some 'postsynapse organization'</newAxiom>
<newAxiom>'postsynaptic membrane organization' EquivalentTo 'cellular component organization' and ('results in organization of' some 'postsynaptic membrane')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001933</classIRI>
<classLabel>negative regulation of protein phosphorylation</classLabel>
<newAxiom>'negative regulation of protein phosphorylation' EquivalentTo 'biological regulation' and ('negatively regulates' some 'protein phosphorylation')</newAxiom>
<newAxiom>'negative regulation of protein phosphorylation' SubClassOf 'regulation of protein phosphorylation'</newAxiom>
<newAxiom>'negative regulation of protein phosphorylation' SubClassOf 'negative regulation of phosphorylation'</newAxiom>
<newAxiom>'negative regulation of protein phosphorylation' SubClassOf 'negative regulation of protein modification process'</newAxiom>
<newAxiom>'negative regulation of protein phosphorylation' SubClassOf 'negatively regulates' some 'protein phosphorylation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001934</classIRI>
<classLabel>positive regulation of protein phosphorylation</classLabel>
<newAxiom>'positive regulation of protein phosphorylation' SubClassOf 'positively regulates' some 'protein phosphorylation'</newAxiom>
<newAxiom>'positive regulation of protein phosphorylation' EquivalentTo 'biological regulation' and ('positively regulates' some 'protein phosphorylation')</newAxiom>
<newAxiom>'positive regulation of protein phosphorylation' SubClassOf 'positive regulation of protein modification process'</newAxiom>
<newAxiom>'positive regulation of protein phosphorylation' SubClassOf 'regulation of protein phosphorylation'</newAxiom>
<newAxiom>'positive regulation of protein phosphorylation' SubClassOf 'positive regulation of phosphorylation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001932</classIRI>
<classLabel>regulation of protein phosphorylation</classLabel>
<newAxiom>'regulation of protein phosphorylation' SubClassOf 'regulation of protein modification process'</newAxiom>
<newAxiom>'regulation of protein phosphorylation' SubClassOf 'regulates' some 'protein phosphorylation'</newAxiom>
<newAxiom>'regulation of protein phosphorylation' EquivalentTo 'biological regulation' and ('regulates' some 'protein phosphorylation')</newAxiom>
<newAxiom>'regulation of protein phosphorylation' SubClassOf 'regulation of phosphorylation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902706</classIRI>
<classLabel>hexose catabolic process to acetate</classLabel>
<newAxiom>'hexose catabolic process to acetate' SubClassOf 'acetate metabolic process'</newAxiom>
<newAxiom>'hexose catabolic process to acetate' EquivalentTo 'catabolic process' and ('has primary output' some 'acetate') and ('has primary input' some 'hexose')</newAxiom>
<newAxiom>'hexose catabolic process to acetate' SubClassOf 'hexose catabolic process'</newAxiom>
<newAxiom>'hexose catabolic process to acetate' SubClassOf 'has primary output' some 'acetate'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006820</classIRI>
<classLabel>anion transport</classLabel>
<newAxiom>'anion transport' EquivalentTo 'transport' and ('has primary input' some 'anion')</newAxiom>
<newAxiom>'anion transport' SubClassOf 'has primary input' some 'anion'</newAxiom>
<newAxiom>'anion transport' SubClassOf 'ion transport'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098960</classIRI>
<classLabel>postsynaptic neurotransmitter receptor activity</classLabel>
<newAxiom>'postsynaptic neurotransmitter receptor activity' EquivalentTo 'neurotransmitter receptor activity' and ('part of' some 'chemical synaptic transmission')</newAxiom>
<newAxiom>'postsynaptic neurotransmitter receptor activity' SubClassOf 'neurotransmitter receptor activity'</newAxiom>
<newAxiom>'postsynaptic neurotransmitter receptor activity' SubClassOf 'part of' some 'chemical synaptic transmission, postsynaptic'</newAxiom>
<newAxiom>'postsynaptic neurotransmitter receptor activity' SubClassOf 'occurs in' some 'postsynaptic membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000273</classIRI>
<classLabel>positive regulation of signaling receptor activity</classLabel>
<newAxiom>'positive regulation of signaling receptor activity' SubClassOf 'positive regulation of molecular function'</newAxiom>
<newAxiom>'positive regulation of signaling receptor activity' SubClassOf 'regulation of signaling receptor activity'</newAxiom>
<newAxiom>'positive regulation of signaling receptor activity' EquivalentTo 'biological regulation' and ('positively regulates' some 'signaling receptor activity')</newAxiom>
<newAxiom>'positive regulation of signaling receptor activity' SubClassOf 'positively regulates' some 'signaling receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000272</classIRI>
<classLabel>negative regulation of signaling receptor activity</classLabel>
<newAxiom>'negative regulation of signaling receptor activity' SubClassOf 'negatively regulates' some 'signaling receptor activity'</newAxiom>
<newAxiom>'negative regulation of signaling receptor activity' EquivalentTo 'biological regulation' and ('negatively regulates' some 'signaling receptor activity')</newAxiom>
<newAxiom>'negative regulation of signaling receptor activity' SubClassOf 'negative regulation of molecular function'</newAxiom>
<newAxiom>'negative regulation of signaling receptor activity' SubClassOf 'regulation of signaling receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902683</classIRI>
<classLabel>regulation of receptor localization to synapse</classLabel>
<newAxiom>'regulation of receptor localization to synapse' EquivalentTo 'biological regulation' and ('regulates' some 'receptor localization to synapse')</newAxiom>
<newAxiom>'regulation of receptor localization to synapse' SubClassOf 'regulates' some 'receptor localization to synapse'</newAxiom>
<newAxiom>'regulation of receptor localization to synapse' SubClassOf 'regulation of localization'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902685</classIRI>
<classLabel>positive regulation of receptor localization to synapse</classLabel>
<newAxiom>'positive regulation of receptor localization to synapse' SubClassOf 'regulation of receptor localization to synapse'</newAxiom>
<newAxiom>'positive regulation of receptor localization to synapse' SubClassOf 'positive regulation of biological process'</newAxiom>
<newAxiom>'positive regulation of receptor localization to synapse' SubClassOf 'positively regulates' some 'receptor localization to synapse'</newAxiom>
<newAxiom>'positive regulation of receptor localization to synapse' EquivalentTo 'biological regulation' and ('positively regulates' some 'receptor localization to synapse')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902684</classIRI>
<classLabel>negative regulation of receptor localization to synapse</classLabel>
<newAxiom>'negative regulation of receptor localization to synapse' SubClassOf 'negatively regulates' some 'receptor localization to synapse'</newAxiom>
<newAxiom>'negative regulation of receptor localization to synapse' SubClassOf 'regulation of receptor localization to synapse'</newAxiom>
<newAxiom>'negative regulation of receptor localization to synapse' EquivalentTo 'biological regulation' and ('negatively regulates' some 'receptor localization to synapse')</newAxiom>
<newAxiom>'negative regulation of receptor localization to synapse' SubClassOf 'negative regulation of biological process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042420</classIRI>
<classLabel>dopamine catabolic process</classLabel>
<newAxiom>'dopamine catabolic process' EquivalentTo 'catabolic process' and ('has primary input' some 'dopaminium(1+)')</newAxiom>
<newAxiom>'dopamine catabolic process' SubClassOf 'dopamine metabolic process'</newAxiom>
<newAxiom>'dopamine catabolic process' SubClassOf 'catabolic process'</newAxiom>
<newAxiom>'dopamine catabolic process' SubClassOf 'has primary input' some 'dopaminium(1+)'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042417</classIRI>
<classLabel>dopamine metabolic process</classLabel>
<newAxiom>'dopamine metabolic process' SubClassOf 'nitrogen compound metabolic process'</newAxiom>
<newAxiom>'dopamine metabolic process' SubClassOf 'has primary input or output' some 'dopaminium(1+)'</newAxiom>
<newAxiom>'dopamine metabolic process' EquivalentTo 'metabolic process' and ('has primary input or output' some 'dopaminium(1+)')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042416</classIRI>
<classLabel>dopamine biosynthetic process</classLabel>
<newAxiom>'dopamine biosynthetic process' SubClassOf 'has primary output' some 'dopaminium(1+)'</newAxiom>
<newAxiom>'dopamine biosynthetic process' SubClassOf 'biosynthetic process'</newAxiom>
<newAxiom>'dopamine biosynthetic process' EquivalentTo 'biosynthetic process' and ('has primary output' some 'dopaminium(1+)')</newAxiom>
<newAxiom>'dopamine biosynthetic process' SubClassOf 'dopamine metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098877</classIRI>
<classLabel>neurotransmitter receptor transport to plasma membrane</classLabel>
<newAxiom>'neurotransmitter receptor transport to plasma membrane' SubClassOf 'neurotransmitter receptor transport'</newAxiom>
<newAxiom>'neurotransmitter receptor transport to plasma membrane' SubClassOf 'protein localization to cell periphery'</newAxiom>
<newAxiom>'neurotransmitter receptor transport to plasma membrane' EquivalentTo 'protein transport' and ('has target end location' some 'plasma membrane') and ('has primary input' some 'neurotransmitter receptor complex')</newAxiom>
<newAxiom>'neurotransmitter receptor transport to plasma membrane' SubClassOf 'establishment of protein localization to membrane'</newAxiom>
<newAxiom>'neurotransmitter receptor transport to plasma membrane' SubClassOf 'vesicle-mediated transport to the plasma membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098878</classIRI>
<classLabel>neurotransmitter receptor complex</classLabel>
<newAxiom>'neurotransmitter receptor complex' SubClassOf 'plasma membrane signaling receptor complex'</newAxiom>
<newAxiom>'neurotransmitter receptor complex' EquivalentTo 'protein-containing complex' and ('capable of' some 'neurotransmitter receptor activity')</newAxiom>
<newAxiom>'neurotransmitter receptor complex' SubClassOf 'capable of' some 'neurotransmitter receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098802</classIRI>
<classLabel>plasma membrane signaling receptor complex</classLabel>
<newAxiom>'plasma membrane signaling receptor complex' SubClassOf 'receptor complex'</newAxiom>
<newAxiom>'plasma membrane signaling receptor complex' SubClassOf 'plasma membrane protein complex'</newAxiom>
<newAxiom>'plasma membrane signaling receptor complex' EquivalentTo 'protein-containing complex' and ('part of' some 'plasma membrane') and ('capable of' some 'signaling receptor activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035240</classIRI>
<classLabel>dopamine binding</classLabel>
<newAxiom>'dopamine binding' EquivalentTo 'binding' and ('has input' some 'dopaminium(1+)')</newAxiom>
<newAxiom>'dopamine binding' SubClassOf 'cation binding'</newAxiom>
<newAxiom>'dopamine binding' SubClassOf 'has input' some 'dopaminium(1+)'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030320</classIRI>
<classLabel>cellular monovalent inorganic anion homeostasis</classLabel>
<newAxiom>'cellular monovalent inorganic anion homeostasis' SubClassOf 'cellular anion homeostasis'</newAxiom>
<newAxiom>'cellular monovalent inorganic anion homeostasis' EquivalentTo 'cellular homeostasis' and ('regulates levels of' some 'monovalent inorganic anion')</newAxiom>
<newAxiom>'cellular monovalent inorganic anion homeostasis' SubClassOf 'monovalent inorganic anion homeostasis'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0065008</classIRI>
<classLabel>regulation of biological quality</classLabel>
<newAxiom>'regulation of biological quality' SubClassOf 'biological regulation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001873</classIRI>
<classLabel>polysaccharide immune receptor activity</classLabel>
<newAxiom>'polysaccharide immune receptor activity' SubClassOf 'has input' some 'polysaccharide'</newAxiom>
<newAxiom>'polysaccharide immune receptor activity' SubClassOf 'has_part' some 'polysaccharide binding'</newAxiom>
<newAxiom>'polysaccharide immune receptor activity' SubClassOf 'pattern recognition receptor activity'</newAxiom>
<newAxiom>'polysaccharide immune receptor activity' EquivalentTo 'signaling receptor activity' and ('has input' some 'polysaccharide')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030292</classIRI>
<classLabel>protein tyrosine kinase inhibitor activity</classLabel>
<newAxiom>'protein tyrosine kinase inhibitor activity' SubClassOf 'part of' some 'negative regulation of protein tyrosine kinase activity'</newAxiom>
<newAxiom>'protein tyrosine kinase inhibitor activity' SubClassOf 'negatively regulates' some 'protein tyrosine kinase activity'</newAxiom>
<newAxiom>'protein tyrosine kinase inhibitor activity' SubClassOf 'protein kinase inhibitor activity'</newAxiom>
<newAxiom>'protein tyrosine kinase inhibitor activity' EquivalentTo 'molecular function regulator activity' and ('negatively regulates' some 'protein tyrosine kinase activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030293</classIRI>
<classLabel>transmembrane receptor protein tyrosine kinase inhibitor activity</classLabel>
<newAxiom>'transmembrane receptor protein tyrosine kinase inhibitor activity' SubClassOf 'protein tyrosine kinase inhibitor activity'</newAxiom>
<newAxiom>'transmembrane receptor protein tyrosine kinase inhibitor activity' SubClassOf 'signaling receptor inhibitor activity'</newAxiom>
<newAxiom>'transmembrane receptor protein tyrosine kinase inhibitor activity' SubClassOf 'negatively regulates' some 'transmembrane receptor protein tyrosine kinase activity'</newAxiom>
<newAxiom>'transmembrane receptor protein tyrosine kinase inhibitor activity' EquivalentTo 'molecular function regulator activity' and ('negatively regulates' some 'transmembrane receptor protein tyrosine kinase activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030295</classIRI>
<classLabel>protein kinase activator activity</classLabel>
<newAxiom>'protein kinase activator activity' SubClassOf 'kinase activator activity'</newAxiom>
<newAxiom>'protein kinase activator activity' SubClassOf 'positively regulates' some 'protein kinase activity'</newAxiom>
<newAxiom>'protein kinase activator activity' EquivalentTo 'molecular function activator activity' and ('positively regulates' some 'protein kinase activity')</newAxiom>
<newAxiom>'protein kinase activator activity' SubClassOf 'protein kinase regulator activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030296</classIRI>
<classLabel>protein tyrosine kinase activator activity</classLabel>
<newAxiom>'protein tyrosine kinase activator activity' SubClassOf 'positively regulates' some 'protein tyrosine kinase activity'</newAxiom>
<newAxiom>'protein tyrosine kinase activator activity' SubClassOf 'protein kinase activator activity'</newAxiom>
<newAxiom>'protein tyrosine kinase activator activity' EquivalentTo 'molecular function activator activity' and ('positively regulates' some 'protein tyrosine kinase activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030297</classIRI>
<classLabel>transmembrane receptor protein tyrosine kinase activator activity</classLabel>
<newAxiom>'transmembrane receptor protein tyrosine kinase activator activity' SubClassOf 'signaling receptor activator activity'</newAxiom>
<newAxiom>'transmembrane receptor protein tyrosine kinase activator activity' EquivalentTo 'molecular function activator activity' and ('positively regulates' some 'transmembrane receptor protein tyrosine kinase activity')</newAxiom>
<newAxiom>'transmembrane receptor protein tyrosine kinase activator activity' SubClassOf 'positively regulates' some 'transmembrane receptor protein tyrosine kinase activity'</newAxiom>
<newAxiom>'transmembrane receptor protein tyrosine kinase activator activity' SubClassOf 'protein tyrosine kinase activator activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902911</classIRI>
<classLabel>protein kinase complex</classLabel>
<newAxiom>'protein kinase complex' SubClassOf 'capable of' some 'protein kinase activity'</newAxiom>
<newAxiom>'protein kinase complex' SubClassOf 'transferase complex, transferring phosphorus-containing groups'</newAxiom>
<newAxiom>'protein kinase complex' EquivalentTo 'protein-containing complex' and ('capable of' some 'protein kinase activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901626</classIRI>
<classLabel>regulation of postsynaptic membrane organization</classLabel>
<newAxiom>'regulation of postsynaptic membrane organization' EquivalentTo 'biological regulation' and ('regulates' some 'postsynaptic membrane organization')</newAxiom>
<newAxiom>'regulation of postsynaptic membrane organization' SubClassOf 'regulates' some 'postsynaptic membrane organization'</newAxiom>
<newAxiom>'regulation of postsynaptic membrane organization' SubClassOf 'regulation of cellular component organization'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901627</classIRI>
<classLabel>negative regulation of postsynaptic membrane organization</classLabel>
<newAxiom>'negative regulation of postsynaptic membrane organization' SubClassOf 'regulation of postsynaptic membrane organization'</newAxiom>
<newAxiom>'negative regulation of postsynaptic membrane organization' SubClassOf 'negative regulation of synapse organization'</newAxiom>
<newAxiom>'negative regulation of postsynaptic membrane organization' EquivalentTo 'biological regulation' and ('negatively regulates' some 'postsynaptic membrane organization')</newAxiom>
<newAxiom>'negative regulation of postsynaptic membrane organization' SubClassOf 'negatively regulates' some 'postsynaptic membrane organization'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901628</classIRI>
<classLabel>positive regulation of postsynaptic membrane organization</classLabel>
<newAxiom>'positive regulation of postsynaptic membrane organization' SubClassOf 'regulation of postsynaptic membrane organization'</newAxiom>
<newAxiom>'positive regulation of postsynaptic membrane organization' SubClassOf 'positively regulates' some 'postsynaptic membrane organization'</newAxiom>
<newAxiom>'positive regulation of postsynaptic membrane organization' SubClassOf 'positive regulation of cellular component organization'</newAxiom>
<newAxiom>'positive regulation of postsynaptic membrane organization' EquivalentTo 'biological regulation' and ('positively regulates' some 'postsynaptic membrane organization')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050731</classIRI>
<classLabel>positive regulation of peptidyl-tyrosine phosphorylation</classLabel>
<newAxiom>'positive regulation of peptidyl-tyrosine phosphorylation' EquivalentTo 'biological regulation' and ('positively regulates' some 'peptidyl-tyrosine phosphorylation')</newAxiom>
<newAxiom>'positive regulation of peptidyl-tyrosine phosphorylation' SubClassOf 'positive regulation of protein phosphorylation'</newAxiom>
<newAxiom>'positive regulation of peptidyl-tyrosine phosphorylation' SubClassOf 'positively regulates' some 'peptidyl-tyrosine phosphorylation'</newAxiom>
<newAxiom>'positive regulation of peptidyl-tyrosine phosphorylation' SubClassOf 'regulation of peptidyl-tyrosine phosphorylation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050732</classIRI>
<classLabel>negative regulation of peptidyl-tyrosine phosphorylation</classLabel>
<newAxiom>'negative regulation of peptidyl-tyrosine phosphorylation' SubClassOf 'regulation of peptidyl-tyrosine phosphorylation'</newAxiom>
<newAxiom>'negative regulation of peptidyl-tyrosine phosphorylation' SubClassOf 'negative regulation of protein phosphorylation'</newAxiom>
<newAxiom>'negative regulation of peptidyl-tyrosine phosphorylation' EquivalentTo 'biological regulation' and ('negatively regulates' some 'peptidyl-tyrosine phosphorylation')</newAxiom>
<newAxiom>'negative regulation of peptidyl-tyrosine phosphorylation' SubClassOf 'negatively regulates' some 'peptidyl-tyrosine phosphorylation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050730</classIRI>
<classLabel>regulation of peptidyl-tyrosine phosphorylation</classLabel>
<newAxiom>'regulation of peptidyl-tyrosine phosphorylation' SubClassOf 'regulation of protein phosphorylation'</newAxiom>
<newAxiom>'regulation of peptidyl-tyrosine phosphorylation' EquivalentTo 'biological regulation' and ('regulates' some 'peptidyl-tyrosine phosphorylation')</newAxiom>
<newAxiom>'regulation of peptidyl-tyrosine phosphorylation' SubClassOf 'regulates' some 'peptidyl-tyrosine phosphorylation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019900</classIRI>
<classLabel>kinase binding</classLabel>
<newAxiom>'kinase binding' SubClassOf 'enzyme binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019901</classIRI>
<classLabel>protein kinase binding</classLabel>
<newAxiom>'protein kinase binding' SubClassOf 'kinase binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098656</classIRI>
<classLabel>anion transmembrane transport</classLabel>
<newAxiom>'anion transmembrane transport' SubClassOf 'ion transmembrane transport'</newAxiom>
<newAxiom>'anion transmembrane transport' EquivalentTo 'transport' and ('results in transport across' some 'membrane') and ('has primary input' some 'anion')</newAxiom>
<newAxiom>'anion transmembrane transport' SubClassOf 'anion transport'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098664</classIRI>
<classLabel>G protein-coupled serotonin receptor signaling pathway</classLabel>
<newAxiom>'G protein-coupled serotonin receptor signaling pathway' SubClassOf 'G protein-coupled receptor signaling pathway'</newAxiom>
<newAxiom>'G protein-coupled serotonin receptor signaling pathway' SubClassOf 'starts with' some 'G protein-coupled serotonin receptor activity'</newAxiom>
<newAxiom>'G protein-coupled serotonin receptor signaling pathway' EquivalentTo 'signal transduction' and ('starts with' some 'G protein-coupled serotonin receptor activity')</newAxiom>
<newAxiom>'G protein-coupled serotonin receptor signaling pathway' SubClassOf 'serotonin receptor signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098665</classIRI>
<classLabel>serotonin receptor complex</classLabel>
<newAxiom>'serotonin receptor complex' EquivalentTo 'protein-containing complex' and ('capable of' some 'serotonin receptor activity')</newAxiom>
<newAxiom>'serotonin receptor complex' SubClassOf 'receptor complex'</newAxiom>
<newAxiom>'serotonin receptor complex' SubClassOf 'capable of' some 'serotonin receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098666</classIRI>
<classLabel>G protein-coupled serotonin receptor complex</classLabel>
<newAxiom>'G protein-coupled serotonin receptor complex' EquivalentTo 'protein-containing complex' and ('capable of' some 'G protein-coupled serotonin receptor activity')</newAxiom>
<newAxiom>'G protein-coupled serotonin receptor complex' SubClassOf 'serotonin receptor complex'</newAxiom>
<newAxiom>'G protein-coupled serotonin receptor complex' SubClassOf 'capable of' some 'G protein-coupled serotonin receptor activity'</newAxiom>
<newAxiom>'G protein-coupled serotonin receptor complex' SubClassOf 'capable of part of' some 'G protein-coupled serotonin receptor signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019887</classIRI>
<classLabel>protein kinase regulator activity</classLabel>
<newAxiom>'protein kinase regulator activity' SubClassOf 'has_part' some 'protein kinase binding'</newAxiom>
<newAxiom>'protein kinase regulator activity' EquivalentTo 'molecular_function' and ('regulates' some 'protein kinase activity')</newAxiom>
<newAxiom>'protein kinase regulator activity' SubClassOf 'kinase regulator activity'</newAxiom>
<newAxiom>'protein kinase regulator activity' SubClassOf 'regulates' some 'protein kinase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019899</classIRI>
<classLabel>enzyme binding</classLabel>
<newAxiom>'enzyme binding' SubClassOf 'protein binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032870</classIRI>
<classLabel>cellular response to hormone stimulus</classLabel>
<newAxiom>'cellular response to hormone stimulus' SubClassOf 'cellular response to endogenous stimulus'</newAxiom>
<newAxiom>'cellular response to hormone stimulus' SubClassOf 'cellular response to organic substance'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060089</classIRI>
<classLabel>molecular transducer activity</classLabel>
<newAxiom>'molecular transducer activity' SubClassOf 'molecular_function'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900449</classIRI>
<classLabel>regulation of glutamate receptor signaling pathway</classLabel>
<newAxiom>'regulation of glutamate receptor signaling pathway' SubClassOf 'regulates' some 'glutamate receptor signaling pathway'</newAxiom>
<newAxiom>'regulation of glutamate receptor signaling pathway' EquivalentTo 'biological regulation' and ('regulates' some 'glutamate receptor signaling pathway')</newAxiom>
<newAxiom>'regulation of glutamate receptor signaling pathway' SubClassOf 'regulation of signal transduction'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900450</classIRI>
<classLabel>negative regulation of glutamate receptor signaling pathway</classLabel>
<newAxiom>'negative regulation of glutamate receptor signaling pathway' SubClassOf 'negatively regulates' some 'glutamate receptor signaling pathway'</newAxiom>
<newAxiom>'negative regulation of glutamate receptor signaling pathway' SubClassOf 'regulation of glutamate receptor signaling pathway'</newAxiom>
<newAxiom>'negative regulation of glutamate receptor signaling pathway' SubClassOf 'negative regulation of signal transduction'</newAxiom>
<newAxiom>'negative regulation of glutamate receptor signaling pathway' EquivalentTo 'biological regulation' and ('negatively regulates' some 'glutamate receptor signaling pathway')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900451</classIRI>
<classLabel>positive regulation of glutamate receptor signaling pathway</classLabel>
<newAxiom>'positive regulation of glutamate receptor signaling pathway' EquivalentTo 'biological regulation' and ('positively regulates' some 'glutamate receptor signaling pathway')</newAxiom>
<newAxiom>'positive regulation of glutamate receptor signaling pathway' SubClassOf 'positive regulation of signal transduction'</newAxiom>
<newAxiom>'positive regulation of glutamate receptor signaling pathway' SubClassOf 'regulation of glutamate receptor signaling pathway'</newAxiom>
<newAxiom>'positive regulation of glutamate receptor signaling pathway' SubClassOf 'positively regulates' some 'glutamate receptor signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_48560</classIRI>
<classLabel>dopaminergic agent</classLabel>
<newAxiom>'dopaminergic agent' SubClassOf 'neurotransmitter agent'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_48540</classIRI>
<classLabel>beta-adrenergic drug</classLabel>
<newAxiom>'beta-adrenergic drug' SubClassOf 'adrenergic agent'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031401</classIRI>
<classLabel>positive regulation of protein modification process</classLabel>
<newAxiom>'positive regulation of protein modification process' SubClassOf 'positive regulation of protein metabolic process'</newAxiom>
<newAxiom>'positive regulation of protein modification process' SubClassOf 'positively regulates' some 'protein modification process'</newAxiom>
<newAxiom>'positive regulation of protein modification process' SubClassOf 'regulation of protein modification process'</newAxiom>
<newAxiom>'positive regulation of protein modification process' EquivalentTo 'biological regulation' and ('positively regulates' some 'protein modification process')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031400</classIRI>
<classLabel>negative regulation of protein modification process</classLabel>
<newAxiom>'negative regulation of protein modification process' SubClassOf 'negative regulation of protein metabolic process'</newAxiom>
<newAxiom>'negative regulation of protein modification process' SubClassOf 'negatively regulates' some 'protein modification process'</newAxiom>
<newAxiom>'negative regulation of protein modification process' SubClassOf 'regulation of protein modification process'</newAxiom>
<newAxiom>'negative regulation of protein modification process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'protein modification process')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006469</classIRI>
<classLabel>negative regulation of protein kinase activity</classLabel>
<newAxiom>'negative regulation of protein kinase activity' SubClassOf 'negative regulation of protein phosphorylation'</newAxiom>
<newAxiom>'negative regulation of protein kinase activity' SubClassOf 'negative regulation of kinase activity'</newAxiom>
<newAxiom>'negative regulation of protein kinase activity' SubClassOf 'negatively regulates' some 'protein kinase activity'</newAxiom>
<newAxiom>'negative regulation of protein kinase activity' EquivalentTo 'biological regulation' and ('negatively regulates' some 'protein kinase activity')</newAxiom>
<newAxiom>'negative regulation of protein kinase activity' SubClassOf 'regulation of protein kinase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006468</classIRI>
<classLabel>protein phosphorylation</classLabel>
<newAxiom>'protein phosphorylation' SubClassOf 'protein modification process'</newAxiom>
<newAxiom>'protein phosphorylation' SubClassOf 'phosphorylation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043401</classIRI>
<classLabel>steroid hormone mediated signaling pathway</classLabel>
<newAxiom>'steroid hormone mediated signaling pathway' SubClassOf 'part of' some 'cellular response to steroid hormone stimulus'</newAxiom>
<newAxiom>'steroid hormone mediated signaling pathway' SubClassOf 'hormone-mediated signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043412</classIRI>
<classLabel>macromolecule modification</classLabel>
<newAxiom>'macromolecule modification' SubClassOf 'macromolecule metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001653</classIRI>
<classLabel>peptide receptor activity</classLabel>
<newAxiom>'peptide receptor activity' SubClassOf 'signaling receptor activity'</newAxiom>
<newAxiom>'peptide receptor activity' EquivalentTo 'signaling receptor activity' and ('has input' some 'peptide')</newAxiom>
<newAxiom>'peptide receptor activity' SubClassOf 'has input' some 'peptide'</newAxiom>
<newAxiom>'peptide receptor activity' SubClassOf 'has_part' some 'peptide binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031399</classIRI>
<classLabel>regulation of protein modification process</classLabel>
<newAxiom>'regulation of protein modification process' SubClassOf 'regulation of protein metabolic process'</newAxiom>
<newAxiom>'regulation of protein modification process' EquivalentTo 'biological regulation' and ('regulates' some 'protein modification process')</newAxiom>
<newAxiom>'regulation of protein modification process' SubClassOf 'regulates' some 'protein modification process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904065</classIRI>
<classLabel>G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission</classLabel>
<newAxiom>'G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission' SubClassOf 'G protein-coupled acetylcholine receptor signaling pathway'</newAxiom>
<newAxiom>'G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission' EquivalentTo 'G protein-coupled acetylcholine receptor signaling pathway' and ('part of' some 'positive regulation of acetylcholine secretion, neurotransmission')</newAxiom>
<newAxiom>'G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission' SubClassOf 'part of' some 'positive regulation of acetylcholine secretion, neurotransmission'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042053</classIRI>
<classLabel>regulation of dopamine metabolic process</classLabel>
<newAxiom>'regulation of dopamine metabolic process' SubClassOf 'regulation of nitrogen compound metabolic process'</newAxiom>
<newAxiom>'regulation of dopamine metabolic process' EquivalentTo 'biological regulation' and ('regulates' some 'dopamine metabolic process')</newAxiom>
<newAxiom>'regulation of dopamine metabolic process' SubClassOf 'regulates' some 'dopamine metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036211</classIRI>
<classLabel>protein modification process</classLabel>
<newAxiom>'protein modification process' SubClassOf 'protein metabolic process'</newAxiom>
<newAxiom>'protein modification process' SubClassOf 'macromolecule modification'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097104</classIRI>
<classLabel>postsynaptic membrane assembly</classLabel>
<newAxiom>'postsynaptic membrane assembly' EquivalentTo 'cellular process' and ('results in assembly of' some 'postsynaptic membrane')</newAxiom>
<newAxiom>'postsynaptic membrane assembly' SubClassOf 'membrane assembly'</newAxiom>
<newAxiom>'postsynaptic membrane assembly' SubClassOf 'part of' some 'postsynapse assembly'</newAxiom>
<newAxiom>'postsynaptic membrane assembly' SubClassOf 'results in assembly of' some 'postsynaptic membrane'</newAxiom>
<newAxiom>'postsynaptic membrane assembly' SubClassOf 'postsynaptic membrane organization'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005009</classIRI>
<classLabel>insulin receptor activity</classLabel>
<newAxiom>'insulin receptor activity' SubClassOf 'in taxon' only 'Eumetazoa'</newAxiom>
<newAxiom>'insulin receptor activity' SubClassOf 'has_part' some 'insulin binding'</newAxiom>
<newAxiom>'insulin receptor activity' SubClassOf 'protein-hormone receptor activity'</newAxiom>
<newAxiom>'insulin receptor activity' EquivalentTo 'signaling receptor activity' and ('has input' some 'insulin gene translation product')</newAxiom>
<newAxiom>'insulin receptor activity' SubClassOf 'part of' some 'insulin receptor signaling pathway'</newAxiom>
<newAxiom>'insulin receptor activity' SubClassOf 'only in taxon' some 'Eumetazoa'</newAxiom>
<newAxiom>'insulin receptor activity' SubClassOf 'transmembrane receptor protein tyrosine kinase activity'</newAxiom>
<newAxiom>'insulin receptor activity' SubClassOf 'has input' some 'insulin gene translation product'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030002</classIRI>
<classLabel>cellular anion homeostasis</classLabel>
<newAxiom>'cellular anion homeostasis' EquivalentTo 'cellular homeostasis' and ('regulates levels of' some 'anion')</newAxiom>
<newAxiom>'cellular anion homeostasis' SubClassOf 'cellular ion homeostasis'</newAxiom>
<newAxiom>'cellular anion homeostasis' SubClassOf 'anion homeostasis'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045964</classIRI>
<classLabel>positive regulation of dopamine metabolic process</classLabel>
<newAxiom>'positive regulation of dopamine metabolic process' SubClassOf 'positive regulation of nitrogen compound metabolic process'</newAxiom>
<newAxiom>'positive regulation of dopamine metabolic process' SubClassOf 'regulation of dopamine metabolic process'</newAxiom>
<newAxiom>'positive regulation of dopamine metabolic process' EquivalentTo 'biological regulation' and ('positively regulates' some 'dopamine metabolic process')</newAxiom>
<newAxiom>'positive regulation of dopamine metabolic process' SubClassOf 'positively regulates' some 'dopamine metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045963</classIRI>
<classLabel>negative regulation of dopamine metabolic process</classLabel>
<newAxiom>'negative regulation of dopamine metabolic process' SubClassOf 'negatively regulates' some 'dopamine metabolic process'</newAxiom>
<newAxiom>'negative regulation of dopamine metabolic process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'dopamine metabolic process')</newAxiom>
<newAxiom>'negative regulation of dopamine metabolic process' SubClassOf 'regulation of dopamine metabolic process'</newAxiom>
<newAxiom>'negative regulation of dopamine metabolic process' SubClassOf 'negative regulation of nitrogen compound metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097120</classIRI>
<classLabel>receptor localization to synapse</classLabel>
<newAxiom>'receptor localization to synapse' SubClassOf 'has primary input' some 'plasma membrane signaling receptor complex'</newAxiom>
<newAxiom>'receptor localization to synapse' SubClassOf 'protein-containing complex localization'</newAxiom>
<newAxiom>'receptor localization to synapse' SubClassOf 'has target end location' some 'synapse'</newAxiom>
<newAxiom>'receptor localization to synapse' EquivalentTo 'localization' and ('has target end location' some 'synapse') and ('has primary input' some 'plasma membrane signaling receptor complex')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030004</classIRI>
<classLabel>cellular monovalent inorganic cation homeostasis</classLabel>
<newAxiom>'cellular monovalent inorganic cation homeostasis' SubClassOf 'monovalent inorganic cation homeostasis'</newAxiom>
<newAxiom>'cellular monovalent inorganic cation homeostasis' EquivalentTo 'cellular homeostasis' and ('regulates levels of' some 'monovalent inorganic cation')</newAxiom>
<newAxiom>'cellular monovalent inorganic cation homeostasis' SubClassOf 'cellular cation homeostasis'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_18243</classIRI>
<classLabel>dopamine</classLabel>
<newAxiom>'dopamine' SubClassOf 'has role' some 'Escherichia coli metabolite'</newAxiom>
<newAxiom>'dopamine' SubClassOf 'has role' some 'mouse metabolite'</newAxiom>
<newAxiom>'dopamine' SubClassOf 'has role' some 'cardiotonic drug'</newAxiom>
<newAxiom>'dopamine' SubClassOf http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of some 'dopaminium(1+)'</newAxiom>
<newAxiom>'dopamine' SubClassOf 'catecholamine'</newAxiom>
<newAxiom>'dopamine' SubClassOf 'has role' some 'human metabolite'</newAxiom>
<newAxiom>'dopamine' SubClassOf 'has role' some 'sympathomimetic agent'</newAxiom>
<newAxiom>'dopamine' SubClassOf 'has role' some 'beta-adrenergic agonist'</newAxiom>
<newAxiom>'dopamine' SubClassOf 'has role' some 'dopaminergic agent'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099637</classIRI>
<classLabel>neurotransmitter receptor transport</classLabel>
<newAxiom>'neurotransmitter receptor transport' SubClassOf 'has primary input' some 'neurotransmitter receptor complex'</newAxiom>
<newAxiom>'neurotransmitter receptor transport' SubClassOf 'protein transport'</newAxiom>
<newAxiom>'neurotransmitter receptor transport' SubClassOf 'protein-containing complex localization'</newAxiom>
<newAxiom>'neurotransmitter receptor transport' EquivalentTo 'protein transport' and ('has primary input' some 'neurotransmitter receptor complex')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099601</classIRI>
<classLabel>regulation of neurotransmitter receptor activity</classLabel>
<newAxiom>'regulation of neurotransmitter receptor activity' SubClassOf 'regulation of signaling receptor activity'</newAxiom>
<newAxiom>'regulation of neurotransmitter receptor activity' EquivalentTo 'biological regulation' and ('regulates' some 'neurotransmitter receptor activity')</newAxiom>
<newAxiom>'regulation of neurotransmitter receptor activity' SubClassOf 'regulates' some 'neurotransmitter receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099602</classIRI>
<classLabel>neurotransmitter receptor regulator activity</classLabel>
<newAxiom>'neurotransmitter receptor regulator activity' SubClassOf 'regulates' some 'neurotransmitter receptor activity'</newAxiom>
<newAxiom>'neurotransmitter receptor regulator activity' SubClassOf 'signaling receptor regulator activity'</newAxiom>
<newAxiom>'neurotransmitter receptor regulator activity' EquivalentTo 'molecular function regulator activity' and ('regulates' some 'neurotransmitter receptor activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018212</classIRI>
<classLabel>peptidyl-tyrosine modification</classLabel>
<newAxiom>'peptidyl-tyrosine modification' SubClassOf 'peptidyl-amino acid modification'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061099</classIRI>
<classLabel>negative regulation of protein tyrosine kinase activity</classLabel>
<newAxiom>'negative regulation of protein tyrosine kinase activity' SubClassOf 'regulation of protein tyrosine kinase activity'</newAxiom>
<newAxiom>'negative regulation of protein tyrosine kinase activity' EquivalentTo 'biological regulation' and ('negatively regulates' some 'protein tyrosine kinase activity')</newAxiom>
<newAxiom>'negative regulation of protein tyrosine kinase activity' SubClassOf 'negative regulation of protein kinase activity'</newAxiom>
<newAxiom>'negative regulation of protein tyrosine kinase activity' SubClassOf 'negative regulation of peptidyl-tyrosine phosphorylation'</newAxiom>
<newAxiom>'negative regulation of protein tyrosine kinase activity' SubClassOf 'negatively regulates' some 'protein tyrosine kinase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061098</classIRI>
<classLabel>positive regulation of protein tyrosine kinase activity</classLabel>
<newAxiom>'positive regulation of protein tyrosine kinase activity' SubClassOf 'positive regulation of protein kinase activity'</newAxiom>
<newAxiom>'positive regulation of protein tyrosine kinase activity' SubClassOf 'positively regulates' some 'protein tyrosine kinase activity'</newAxiom>
<newAxiom>'positive regulation of protein tyrosine kinase activity' SubClassOf 'positive regulation of peptidyl-tyrosine phosphorylation'</newAxiom>
<newAxiom>'positive regulation of protein tyrosine kinase activity' EquivalentTo 'biological regulation' and ('positively regulates' some 'protein tyrosine kinase activity')</newAxiom>
<newAxiom>'positive regulation of protein tyrosine kinase activity' SubClassOf 'regulation of protein tyrosine kinase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061097</classIRI>
<classLabel>regulation of protein tyrosine kinase activity</classLabel>
<newAxiom>'regulation of protein tyrosine kinase activity' SubClassOf 'regulation of peptidyl-tyrosine phosphorylation'</newAxiom>
<newAxiom>'regulation of protein tyrosine kinase activity' SubClassOf 'regulation of protein kinase activity'</newAxiom>
<newAxiom>'regulation of protein tyrosine kinase activity' EquivalentTo 'biological regulation' and ('regulates' some 'protein tyrosine kinase activity')</newAxiom>
<newAxiom>'regulation of protein tyrosine kinase activity' SubClassOf 'regulates' some 'protein tyrosine kinase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045860</classIRI>
<classLabel>positive regulation of protein kinase activity</classLabel>
<newAxiom>'positive regulation of protein kinase activity' SubClassOf 'positive regulation of protein phosphorylation'</newAxiom>
<newAxiom>'positive regulation of protein kinase activity' EquivalentTo 'biological regulation' and ('positively regulates' some 'protein kinase activity')</newAxiom>
<newAxiom>'positive regulation of protein kinase activity' SubClassOf 'positively regulates' some 'protein kinase activity'</newAxiom>
<newAxiom>'positive regulation of protein kinase activity' SubClassOf 'positive regulation of kinase activity'</newAxiom>
<newAxiom>'positive regulation of protein kinase activity' SubClassOf 'regulation of protein kinase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045859</classIRI>
<classLabel>regulation of protein kinase activity</classLabel>
<newAxiom>'regulation of protein kinase activity' SubClassOf 'regulation of kinase activity'</newAxiom>
<newAxiom>'regulation of protein kinase activity' SubClassOf 'regulation of protein phosphorylation'</newAxiom>
<newAxiom>'regulation of protein kinase activity' EquivalentTo 'biological regulation' and ('regulates' some 'protein kinase activity')</newAxiom>
<newAxiom>'regulation of protein kinase activity' SubClassOf 'regulates' some 'protein kinase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043235</classIRI>
<classLabel>receptor complex</classLabel>
<newAxiom>'receptor complex' SubClassOf 'protein-containing complex'</newAxiom>
<newAxiom>'receptor complex' EquivalentTo 'protein-containing complex' and ('capable of' some 'signaling receptor activity')</newAxiom>
<newAxiom>'receptor complex' SubClassOf 'capable of' some 'signaling receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018193</classIRI>
<classLabel>peptidyl-amino acid modification</classLabel>
<newAxiom>'peptidyl-amino acid modification' SubClassOf 'has input' some 'amino-acid residue'</newAxiom>
<newAxiom>'peptidyl-amino acid modification' SubClassOf 'protein modification process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099528</classIRI>
<classLabel>G protein-coupled neurotransmitter receptor activity</classLabel>
<newAxiom>'G protein-coupled neurotransmitter receptor activity' SubClassOf 'G protein-coupled receptor activity'</newAxiom>
<newAxiom>'G protein-coupled neurotransmitter receptor activity' SubClassOf 'neurotransmitter receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099529</classIRI>
<classLabel>neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential</classLabel>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' EquivalentTo 'neurotransmitter receptor activity' and ('part of' some 'regulation of postsynaptic membrane potential')</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf 'postsynaptic neurotransmitter receptor activity'</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf 'part of' some 'regulation of postsynaptic membrane potential'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099530</classIRI>
<classLabel>G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential</classLabel>
<newAxiom>'G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential' EquivalentTo 'G protein-coupled receptor activity' and ('part of' some 'regulation of postsynaptic membrane potential')</newAxiom>
<newAxiom>'G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf 'part of' some 'regulation of postsynaptic membrane potential'</newAxiom>
<newAxiom>'G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf 'G protein-coupled receptor activity'</newAxiom>
<newAxiom>'G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf 'occurs in' some 'postsynaptic membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140231</classIRI>
<classLabel>anterograde axonal transport of neurotransmitter receptor complex</classLabel>
<newAxiom>'anterograde axonal transport of neurotransmitter receptor complex' SubClassOf 'neurotransmitter receptor transport'</newAxiom>
<newAxiom>'anterograde axonal transport of neurotransmitter receptor complex' EquivalentTo 'transport' and ('occurs in' some 'axon cytoplasm') and ('has target end location' some 'presynapse') and ('results in transport along' some 'microtubule') and ('has primary input' some 'neurotransmitter receptor complex')</newAxiom>
<newAxiom>'anterograde axonal transport of neurotransmitter receptor complex' SubClassOf 'receptor localization to synapse'</newAxiom>
<newAxiom>'anterograde axonal transport of neurotransmitter receptor complex' SubClassOf 'anterograde axonal protein transport'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099579</classIRI>
<classLabel>G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential</classLabel>
<newAxiom>'G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf 'neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential'</newAxiom>
<newAxiom>'G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' EquivalentTo 'G protein-coupled neurotransmitter receptor activity' and ('part of' some 'regulation of postsynaptic membrane potential')</newAxiom>
<newAxiom>'G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf 'G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential'</newAxiom>
<newAxiom>'G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf 'G protein-coupled neurotransmitter receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099589</classIRI>
<classLabel>serotonin receptor activity</classLabel>
<newAxiom>'serotonin receptor activity' SubClassOf 'has input' some 'serotonin(1+)'</newAxiom>
<newAxiom>'serotonin receptor activity' SubClassOf 'transmembrane signaling receptor activity'</newAxiom>
<newAxiom>'serotonin receptor activity' EquivalentTo 'transmembrane signaling receptor activity' and ('has input' some 'serotonin(1+)')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018108</classIRI>
<classLabel>peptidyl-tyrosine phosphorylation</classLabel>
<newAxiom>'peptidyl-tyrosine phosphorylation' SubClassOf 'protein phosphorylation'</newAxiom>
<newAxiom>'peptidyl-tyrosine phosphorylation' SubClassOf 'peptidyl-tyrosine modification'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045745</classIRI>
<classLabel>positive regulation of G protein-coupled receptor signaling pathway</classLabel>
<newAxiom>'positive regulation of G protein-coupled receptor signaling pathway' EquivalentTo 'biological regulation' and ('positively regulates' some 'G protein-coupled receptor signaling pathway')</newAxiom>
<newAxiom>'positive regulation of G protein-coupled receptor signaling pathway' SubClassOf 'positively regulates' some 'G protein-coupled receptor signaling pathway'</newAxiom>
<newAxiom>'positive regulation of G protein-coupled receptor signaling pathway' SubClassOf 'positive regulation of signal transduction'</newAxiom>
<newAxiom>'positive regulation of G protein-coupled receptor signaling pathway' SubClassOf 'regulation of G protein-coupled receptor signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045744</classIRI>
<classLabel>negative regulation of G protein-coupled receptor signaling pathway</classLabel>
<newAxiom>'negative regulation of G protein-coupled receptor signaling pathway' SubClassOf 'negative regulation of signal transduction'</newAxiom>
<newAxiom>'negative regulation of G protein-coupled receptor signaling pathway' SubClassOf 'regulation of G protein-coupled receptor signaling pathway'</newAxiom>
<newAxiom>'negative regulation of G protein-coupled receptor signaling pathway' EquivalentTo 'biological regulation' and ('negatively regulates' some 'G protein-coupled receptor signaling pathway')</newAxiom>
<newAxiom>'negative regulation of G protein-coupled receptor signaling pathway' SubClassOf 'negatively regulates' some 'G protein-coupled receptor signaling pathway'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055083</classIRI>
<classLabel>monovalent inorganic anion homeostasis</classLabel>
<newAxiom>'monovalent inorganic anion homeostasis' SubClassOf 'inorganic ion homeostasis'</newAxiom>
<newAxiom>'monovalent inorganic anion homeostasis' SubClassOf 'regulates levels of' some 'monovalent inorganic anion'</newAxiom>
<newAxiom>'monovalent inorganic anion homeostasis' EquivalentTo 'chemical homeostasis' and ('regulates levels of' some 'monovalent inorganic anion')</newAxiom>
<newAxiom>'monovalent inorganic anion homeostasis' SubClassOf 'anion homeostasis'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055081</classIRI>
<classLabel>anion homeostasis</classLabel>
<newAxiom>'anion homeostasis' SubClassOf 'ion homeostasis'</newAxiom>
<newAxiom>'anion homeostasis' EquivalentTo 'chemical homeostasis' and ('regulates levels of' some 'anion')</newAxiom>
<newAxiom>'anion homeostasis' SubClassOf 'regulates levels of' some 'anion'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015872</classIRI>
<classLabel>dopamine transport</classLabel>
<newAxiom>'dopamine transport' EquivalentTo 'transport' and ('has primary input' some 'dopaminium(1+)')</newAxiom>
<newAxiom>'dopamine transport' SubClassOf 'nitrogen compound transport'</newAxiom>
<newAxiom>'dopamine transport' SubClassOf 'has primary input' some 'dopaminium(1+)'</newAxiom>
<newAxiom>'dopamine transport' SubClassOf 'cation transport'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055067</classIRI>
<classLabel>monovalent inorganic cation homeostasis</classLabel>
<newAxiom>'monovalent inorganic cation homeostasis' SubClassOf 'regulates levels of' some 'monovalent inorganic cation'</newAxiom>
<newAxiom>'monovalent inorganic cation homeostasis' EquivalentTo 'chemical homeostasis' and ('regulates levels of' some 'monovalent inorganic cation')</newAxiom>
<newAxiom>'monovalent inorganic cation homeostasis' SubClassOf 'cation homeostasis'</newAxiom>
<newAxiom>'monovalent inorganic cation homeostasis' SubClassOf 'inorganic ion homeostasis'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033602</classIRI>
<classLabel>negative regulation of dopamine secretion</classLabel>
<newAxiom>'negative regulation of dopamine secretion' SubClassOf 'negative regulation of ion transport'</newAxiom>
<newAxiom>'negative regulation of dopamine secretion' SubClassOf 'negatively regulates' some 'dopamine secretion'</newAxiom>
<newAxiom>'negative regulation of dopamine secretion' SubClassOf 'regulation of dopamine secretion'</newAxiom>
<newAxiom>'negative regulation of dopamine secretion' EquivalentTo 'biological regulation' and ('negatively regulates' some 'dopamine secretion')</newAxiom>
<newAxiom>'negative regulation of dopamine secretion' SubClassOf 'negative regulation of secretion by cell'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033603</classIRI>
<classLabel>positive regulation of dopamine secretion</classLabel>
<newAxiom>'positive regulation of dopamine secretion' SubClassOf 'positive regulation of secretion by cell'</newAxiom>
<newAxiom>'positive regulation of dopamine secretion' EquivalentTo 'biological regulation' and ('positively regulates' some 'dopamine secretion')</newAxiom>
<newAxiom>'positive regulation of dopamine secretion' SubClassOf 'positive regulation of ion transport'</newAxiom>
<newAxiom>'positive regulation of dopamine secretion' SubClassOf 'positively regulates' some 'dopamine secretion'</newAxiom>
<newAxiom>'positive regulation of dopamine secretion' SubClassOf 'regulation of dopamine secretion'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0086103</classIRI>
<classLabel>G protein-coupled receptor signaling pathway involved in heart process</classLabel>
<newAxiom>'G protein-coupled receptor signaling pathway involved in heart process' SubClassOf 'part of' some 'heart process'</newAxiom>
<newAxiom>'G protein-coupled receptor signaling pathway involved in heart process' SubClassOf 'G protein-coupled receptor signaling pathway'</newAxiom>
<newAxiom>'G protein-coupled receptor signaling pathway involved in heart process' EquivalentTo 'G protein-coupled receptor signaling pathway' and ('part of' some 'heart process')</newAxiom>
</deletedClass>
</deletedClasses>
</diffReport>