<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
102
</numberChangedClasses>
<numberNewClasses>
4
</numberNewClasses>
<numberDeletedClasses>
94
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043393</classIRI>
<classLabel>regulation of protein binding</classLabel>
<deletedAxiom>&apos;regulation of protein binding&apos; SubClassOf &apos;regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein binding&apos; SubClassOf &apos;regulates&apos; some &apos;protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;protein binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010469</classIRI>
<classLabel>regulation of signaling receptor activity</classLabel>
<deletedAxiom>&apos;regulation of signaling receptor activity&apos; SubClassOf &apos;regulates&apos; some &apos;signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of signaling receptor activity&apos; SubClassOf &apos;regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of signaling receptor activity&apos; SubClassOf &apos;regulation of signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of signaling receptor activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;signaling receptor activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008152</classIRI>
<classLabel>metabolic process</classLabel>
<deletedAxiom>&apos;metabolic process&apos; SubClassOf &apos;biological_process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044237</classIRI>
<classLabel>cellular metabolic process</classLabel>
<deletedAxiom>&apos;cellular metabolic process&apos; SubClassOf &apos;metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular metabolic process&apos; SubClassOf &apos;cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000040</classIRI>
<classLabel>material entity</classLabel>
<deletedAxiom>&apos;material entity&apos; DisjointWith &apos;part of&apos; some &apos;immaterial entity&apos;</deletedAxiom>
<deletedAxiom>&apos;material entity&apos; DisjointWith &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CARO_0000014</classIRI>
<classLabel>cell part</classLabel>
<deletedAxiom>&apos;cell part&apos; SubClassOf &apos;connected anatomical structure&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900120</classIRI>
<classLabel>regulation of receptor binding</classLabel>
<deletedAxiom>&apos;regulation of receptor binding&apos; SubClassOf &apos;regulates&apos; some &apos;signaling receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of receptor binding&apos; SubClassOf &apos;regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of receptor binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;signaling receptor binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900121</classIRI>
<classLabel>negative regulation of receptor binding</classLabel>
<deletedAxiom>&apos;negative regulation of receptor binding&apos; SubClassOf &apos;negative regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of receptor binding&apos; SubClassOf &apos;regulation of receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of receptor binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;signaling receptor binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of receptor binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;signaling receptor binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900122</classIRI>
<classLabel>positive regulation of receptor binding</classLabel>
<deletedAxiom>&apos;positive regulation of receptor binding&apos; SubClassOf &apos;positive regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of receptor binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;signaling receptor binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of receptor binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;signaling receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of receptor binding&apos; SubClassOf &apos;regulation of receptor binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005515</classIRI>
<classLabel>protein binding</classLabel>
<deletedAxiom>&apos;protein binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000273</classIRI>
<classLabel>positive regulation of signaling receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of signaling receptor activity&apos; SubClassOf &apos;positive regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signaling receptor activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;signaling receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signaling receptor activity&apos; SubClassOf &apos;regulation of signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signaling receptor activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000272</classIRI>
<classLabel>negative regulation of signaling receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of signaling receptor activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signaling receptor activity&apos; SubClassOf &apos;negative regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signaling receptor activity&apos; SubClassOf &apos;regulation of signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signaling receptor activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;signaling receptor activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006793</classIRI>
<classLabel>phosphorus metabolic process</classLabel>
<deletedAxiom>&apos;phosphorus metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/RO_0002577</classIRI>
<classLabel>system</classLabel>
<deletedAxiom>&apos;system&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006796</classIRI>
<classLabel>phosphate-containing compound metabolic process</classLabel>
<deletedAxiom>&apos;phosphate-containing compound metabolic process&apos; SubClassOf &apos;phosphorus metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051338</classIRI>
<classLabel>regulation of transferase activity</classLabel>
<deletedAxiom>&apos;regulation of transferase activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;transferase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of transferase activity&apos; SubClassOf &apos;regulation of catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transferase activity&apos; SubClassOf &apos;regulates&apos; some &apos;transferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005488</classIRI>
<classLabel>binding</classLabel>
<deletedAxiom>&apos;binding&apos; SubClassOf &apos;molecular_function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051348</classIRI>
<classLabel>negative regulation of transferase activity</classLabel>
<deletedAxiom>&apos;negative regulation of transferase activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;transferase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transferase activity&apos; SubClassOf &apos;regulation of transferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transferase activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;transferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transferase activity&apos; SubClassOf &apos;negative regulation of catalytic activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051347</classIRI>
<classLabel>positive regulation of transferase activity</classLabel>
<deletedAxiom>&apos;positive regulation of transferase activity&apos; SubClassOf &apos;positive regulation of catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transferase activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;transferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transferase activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;transferase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transferase activity&apos; SubClassOf &apos;regulation of transferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045936</classIRI>
<classLabel>negative regulation of phosphate metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of phosphate metabolic process&apos; SubClassOf &apos;negative regulation of phosphorus metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphate metabolic process&apos; SubClassOf &apos;regulation of phosphate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphate metabolic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;phosphate-containing compound metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphate metabolic process&apos; SubClassOf &apos;negatively regulates&apos; some &apos;phosphate-containing compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045937</classIRI>
<classLabel>positive regulation of phosphate metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of phosphate metabolic process&apos; SubClassOf &apos;positively regulates&apos; some &apos;phosphate-containing compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of phosphate metabolic process&apos; SubClassOf &apos;regulation of phosphate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of phosphate metabolic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;phosphate-containing compound metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of phosphate metabolic process&apos; SubClassOf &apos;positive regulation of phosphorus metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031324</classIRI>
<classLabel>negative regulation of cellular metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of cellular metabolic process&apos; SubClassOf &apos;negative regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular metabolic process&apos; SubClassOf &apos;negatively regulates&apos; some &apos;cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular metabolic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;cellular metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031323</classIRI>
<classLabel>regulation of cellular metabolic process</classLabel>
<deletedAxiom>&apos;regulation of cellular metabolic process&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular metabolic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;cellular metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular metabolic process&apos; SubClassOf &apos;regulates&apos; some &apos;cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031325</classIRI>
<classLabel>positive regulation of cellular metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of cellular metabolic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;cellular metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular metabolic process&apos; SubClassOf &apos;positively regulates&apos; some &apos;cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular metabolic process&apos; SubClassOf &apos;positive regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009892</classIRI>
<classLabel>negative regulation of metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of metabolic process&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of metabolic process&apos; SubClassOf &apos;negatively regulates&apos; some &apos;metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of metabolic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;metabolic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000141</classIRI>
<classLabel>immaterial entity</classLabel>
<deletedAxiom>&apos;immaterial entity&apos; SubClassOf &apos;independent continuant&apos;</deletedAxiom>
<deletedAxiom>&apos;immaterial entity&apos; DisjointWith &apos;has_part&apos; some &apos;material entity&apos;</deletedAxiom>
<deletedAxiom>&apos;material entity&apos; DisjointWith &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009893</classIRI>
<classLabel>positive regulation of metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of metabolic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of metabolic process&apos; SubClassOf &apos;positively regulates&apos; some &apos;metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of metabolic process&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019220</classIRI>
<classLabel>regulation of phosphate metabolic process</classLabel>
<deletedAxiom>&apos;regulation of phosphate metabolic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;phosphate-containing compound metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of phosphate metabolic process&apos; SubClassOf &apos;regulation of phosphorus metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of phosphate metabolic process&apos; SubClassOf &apos;regulates&apos; some &apos;phosphate-containing compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019222</classIRI>
<classLabel>regulation of metabolic process</classLabel>
<deletedAxiom>&apos;regulation of metabolic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of metabolic process&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of metabolic process&apos; SubClassOf &apos;regulates&apos; some &apos;metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0000973</classIRI>
<classLabel>porosity</classLabel>
<deletedAxiom>&apos;porosity&apos; SubClassOf &apos;permeability&apos;</deletedAxiom>
<newAxiom>&apos;porosity&apos; SubClassOf &apos;structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007165</classIRI>
<classLabel>signal transduction</classLabel>
<deletedAxiom>&apos;signal transduction&apos; SubClassOf &apos;part of&apos; some &apos;cellular response to stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;signal transduction&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;signal transduction&apos; SubClassOf &apos;part of&apos; some &apos;cell communication&apos;</deletedAxiom>
<deletedAxiom>&apos;signal transduction&apos; SubClassOf &apos;part of&apos; some &apos;signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;signal transduction&apos; SubClassOf &apos;cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048522</classIRI>
<classLabel>positive regulation of cellular process</classLabel>
<deletedAxiom>&apos;positive regulation of cellular process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;cellular process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular process&apos; SubClassOf &apos;positively regulates&apos; some &apos;cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular process&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular process&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048523</classIRI>
<classLabel>negative regulation of cellular process</classLabel>
<deletedAxiom>&apos;negative regulation of cellular process&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular process&apos; SubClassOf &apos;negatively regulates&apos; some &apos;cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular process&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;cellular process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048518</classIRI>
<classLabel>positive regulation of biological process</classLabel>
<deletedAxiom>&apos;positive regulation of biological process&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of biological process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;biological_process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of biological process&apos; SubClassOf &apos;positively regulates&apos; some &apos;biological_process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048519</classIRI>
<classLabel>negative regulation of biological process</classLabel>
<deletedAxiom>&apos;negative regulation of biological process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;biological_process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of biological process&apos; SubClassOf &apos;negatively regulates&apos; some &apos;biological_process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of biological process&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051716</classIRI>
<classLabel>cellular response to stimulus</classLabel>
<deletedAxiom>&apos;cellular response to stimulus&apos; SubClassOf &apos;response to stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular response to stimulus&apos; SubClassOf &apos;cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048585</classIRI>
<classLabel>negative regulation of response to stimulus</classLabel>
<deletedAxiom>&apos;negative regulation of response to stimulus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;response to stimulus&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of response to stimulus&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of response to stimulus&apos; SubClassOf &apos;negatively regulates&apos; some &apos;response to stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of response to stimulus&apos; SubClassOf &apos;regulation of response to stimulus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048583</classIRI>
<classLabel>regulation of response to stimulus</classLabel>
<deletedAxiom>&apos;regulation of response to stimulus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;response to stimulus&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of response to stimulus&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of response to stimulus&apos; SubClassOf &apos;regulates&apos; some &apos;response to stimulus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048584</classIRI>
<classLabel>positive regulation of response to stimulus</classLabel>
<deletedAxiom>&apos;positive regulation of response to stimulus&apos; SubClassOf &apos;regulation of response to stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of response to stimulus&apos; SubClassOf &apos;positively regulates&apos; some &apos;response to stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of response to stimulus&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of response to stimulus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;response to stimulus&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050896</classIRI>
<classLabel>response to stimulus</classLabel>
<deletedAxiom>&apos;response to stimulus&apos; SubClassOf &apos;biological_process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098772</classIRI>
<classLabel>molecular function regulator</classLabel>
<deletedAxiom>&apos;molecular function regulator&apos; SubClassOf &apos;molecular_function&apos;</deletedAxiom>
<deletedAxiom>&apos;molecular function regulator&apos; SubClassOf &apos;part of&apos; some &apos;regulation of molecular function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048018</classIRI>
<classLabel>receptor ligand activity</classLabel>
<deletedAxiom>&apos;receptor ligand activity&apos; SubClassOf &apos;signaling receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;receptor ligand activity&apos; SubClassOf &apos;part of&apos; some &apos;signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;receptor ligand activity&apos; SubClassOf &apos;signaling receptor activator activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016020</classIRI>
<classLabel>membrane</classLabel>
<deletedAxiom>&apos;membrane&apos; SubClassOf &apos;cell part&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000006</classIRI>
<classLabel>spatial region</classLabel>
<deletedAxiom>&apos;spatial region&apos; SubClassOf &apos;immaterial entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000004</classIRI>
<classLabel>independent continuant</classLabel>
<deletedAxiom>&apos;independent continuant&apos; DisjointWith &apos;generically dependent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000031</classIRI>
<classLabel>generically dependent continuant</classLabel>
<deletedAxiom>&apos;independent continuant&apos; DisjointWith &apos;generically dependent continuant&apos;</deletedAxiom>
<deletedAxiom>&apos;specifically dependent continuant&apos; DisjointWith &apos;generically dependent continuant&apos;</deletedAxiom>
<deletedAxiom>&apos;generically dependent continuant&apos; SubClassOf &apos;continuant&apos;</deletedAxiom>
<deletedAxiom>&apos;generically dependent continuant&apos; SubClassOf &apos;part of&apos; only &apos;generically dependent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000017</classIRI>
<classLabel>realizable entity</classLabel>
<deletedAxiom>&apos;realizable entity&apos; SubClassOf &apos;part of&apos; only &apos;realizable entity&apos;</deletedAxiom>
<deletedAxiom>&apos;realizable entity&apos; SubClassOf &apos;specifically dependent continuant&apos;</deletedAxiom>
<deletedAxiom>&apos;realizable entity&apos; DisjointWith &apos;quality&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000019</classIRI>
<classLabel>quality</classLabel>
<deletedAxiom>&apos;realizable entity&apos; DisjointWith &apos;quality&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000020</classIRI>
<classLabel>specifically dependent continuant</classLabel>
<deletedAxiom>&apos;specifically dependent continuant&apos; DisjointWith &apos;generically dependent continuant&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042327</classIRI>
<classLabel>positive regulation of phosphorylation</classLabel>
<deletedAxiom>&apos;positive regulation of phosphorylation&apos; SubClassOf &apos;positive regulation of phosphate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of phosphorylation&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of phosphorylation&apos; SubClassOf &apos;regulation of phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of phosphorylation&apos; SubClassOf &apos;positively regulates&apos; some &apos;phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042326</classIRI>
<classLabel>negative regulation of phosphorylation</classLabel>
<deletedAxiom>&apos;negative regulation of phosphorylation&apos; SubClassOf &apos;negative regulation of phosphate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphorylation&apos; SubClassOf &apos;negatively regulates&apos; some &apos;phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphorylation&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphorylation&apos; SubClassOf &apos;regulation of phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042325</classIRI>
<classLabel>regulation of phosphorylation</classLabel>
<deletedAxiom>&apos;regulation of phosphorylation&apos; SubClassOf &apos;regulation of phosphate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of phosphorylation&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of phosphorylation&apos; SubClassOf &apos;regulates&apos; some &apos;phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0065009</classIRI>
<classLabel>regulation of molecular function</classLabel>
<deletedAxiom>&apos;regulation of molecular function&apos; SubClassOf &apos;regulates&apos; some &apos;molecular_function&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of molecular function&apos; SubClassOf &apos;biological regulation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of molecular function&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;molecular_function&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0065007</classIRI>
<classLabel>biological regulation</classLabel>
<deletedAxiom>&apos;biological regulation&apos; SubClassOf &apos;biological_process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007154</classIRI>
<classLabel>cell communication</classLabel>
<deletedAxiom>&apos;cell communication&apos; SubClassOf &apos;cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044464</classIRI>
<classLabel>cell part</classLabel>
<classLabel>obsolete cell part</classLabel>
<deletedAxiom>&apos;cell part&apos; SubClassOf &apos;cell part&apos;</deletedAxiom>
<newAxiom>&apos;cell part&apos; SubClassOf &apos;connected anatomical structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035556</classIRI>
<classLabel>intracellular signal transduction</classLabel>
<deletedAxiom>&apos;intracellular signal transduction&apos; SubClassOf &apos;occurs in&apos; some &apos;intracellular&apos;</deletedAxiom>
<deletedAxiom>&apos;intracellular signal transduction&apos; EquivalentTo &apos;signal transduction&apos; and (&apos;occurs in&apos; some &apos;intracellular&apos;)</deletedAxiom>
<deletedAxiom>&apos;intracellular signal transduction&apos; SubClassOf &apos;signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0002539</classIRI>
<classLabel>ring shaped</classLabel>
<deletedAxiom>&apos;ring shaped&apos; SubClassOf &apos;shape&apos;</deletedAxiom>
<newAxiom>&apos;ring shaped&apos; SubClassOf &apos;elliptic&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032091</classIRI>
<classLabel>negative regulation of protein binding</classLabel>
<deletedAxiom>&apos;negative regulation of protein binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;protein binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein binding&apos; SubClassOf &apos;negative regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein binding&apos; SubClassOf &apos;regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032092</classIRI>
<classLabel>positive regulation of protein binding</classLabel>
<deletedAxiom>&apos;positive regulation of protein binding&apos; SubClassOf &apos;regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein binding&apos; SubClassOf &apos;positive regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;protein binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050789</classIRI>
<classLabel>regulation of biological process</classLabel>
<deletedAxiom>&apos;regulation of biological process&apos; SubClassOf &apos;biological regulation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of biological process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;biological_process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of biological process&apos; SubClassOf &apos;regulates&apos; some &apos;biological_process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050790</classIRI>
<classLabel>regulation of catalytic activity</classLabel>
<deletedAxiom>&apos;regulation of catalytic activity&apos; SubClassOf &apos;regulates&apos; some &apos;catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of catalytic activity&apos; SubClassOf &apos;regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of catalytic activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;catalytic activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050794</classIRI>
<classLabel>regulation of cellular process</classLabel>
<deletedAxiom>&apos;regulation of cellular process&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;cellular process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular process&apos; SubClassOf &apos;regulates&apos; some &apos;cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044092</classIRI>
<classLabel>negative regulation of molecular function</classLabel>
<deletedAxiom>&apos;negative regulation of molecular function&apos; SubClassOf &apos;negatively regulates&apos; some &apos;molecular_function&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of molecular function&apos; SubClassOf &apos;regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of molecular function&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;molecular_function&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044093</classIRI>
<classLabel>positive regulation of molecular function</classLabel>
<deletedAxiom>&apos;positive regulation of molecular function&apos; SubClassOf &apos;positively regulates&apos; some &apos;molecular_function&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of molecular function&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;molecular_function&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of molecular function&apos; SubClassOf &apos;regulation of molecular function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902531</classIRI>
<classLabel>regulation of intracellular signal transduction</classLabel>
<deletedAxiom>&apos;regulation of intracellular signal transduction&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;intracellular signal transduction&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of intracellular signal transduction&apos; SubClassOf &apos;regulates&apos; some &apos;intracellular signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of intracellular signal transduction&apos; SubClassOf &apos;regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902533</classIRI>
<classLabel>positive regulation of intracellular signal transduction</classLabel>
<deletedAxiom>&apos;positive regulation of intracellular signal transduction&apos; SubClassOf &apos;regulation of intracellular signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of intracellular signal transduction&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;intracellular signal transduction&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of intracellular signal transduction&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of intracellular signal transduction&apos; SubClassOf &apos;positively regulates&apos; some &apos;intracellular signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902532</classIRI>
<classLabel>negative regulation of intracellular signal transduction</classLabel>
<deletedAxiom>&apos;negative regulation of intracellular signal transduction&apos; SubClassOf &apos;negatively regulates&apos; some &apos;intracellular signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of intracellular signal transduction&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;intracellular signal transduction&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of intracellular signal transduction&apos; SubClassOf &apos;regulation of intracellular signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of intracellular signal transduction&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016310</classIRI>
<classLabel>phosphorylation</classLabel>
<deletedAxiom>&apos;phosphorylation&apos; SubClassOf &apos;phosphate-containing compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/ENVO_01000254</classIRI>
<classLabel>environmental system</classLabel>
<deletedAxiom>&apos;environmental system&apos; SubClassOf &apos;system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051100</classIRI>
<classLabel>negative regulation of binding</classLabel>
<deletedAxiom>&apos;negative regulation of binding&apos; SubClassOf &apos;regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of binding&apos; SubClassOf &apos;negative regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051174</classIRI>
<classLabel>regulation of phosphorus metabolic process</classLabel>
<deletedAxiom>&apos;regulation of phosphorus metabolic process&apos; SubClassOf &apos;regulates&apos; some &apos;phosphorus metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of phosphorus metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of phosphorus metabolic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;phosphorus metabolic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060089</classIRI>
<classLabel>molecular transducer activity</classLabel>
<deletedAxiom>&apos;molecular transducer activity&apos; SubClassOf &apos;molecular_function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043549</classIRI>
<classLabel>regulation of kinase activity</classLabel>
<deletedAxiom>&apos;regulation of kinase activity&apos; SubClassOf &apos;regulation of phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of kinase activity&apos; SubClassOf &apos;regulates&apos; some &apos;kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of kinase activity&apos; SubClassOf &apos;regulation of transferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of kinase activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;kinase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010647</classIRI>
<classLabel>positive regulation of cell communication</classLabel>
<deletedAxiom>&apos;positive regulation of cell communication&apos; SubClassOf &apos;positive regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cell communication&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;cell communication&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cell communication&apos; SubClassOf &apos;positively regulates&apos; some &apos;cell communication&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cell communication&apos; SubClassOf &apos;regulation of cell communication&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010648</classIRI>
<classLabel>negative regulation of cell communication</classLabel>
<deletedAxiom>&apos;negative regulation of cell communication&apos; SubClassOf &apos;regulation of cell communication&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cell communication&apos; SubClassOf &apos;negatively regulates&apos; some &apos;cell communication&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cell communication&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;cell communication&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cell communication&apos; SubClassOf &apos;negative regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010646</classIRI>
<classLabel>regulation of cell communication</classLabel>
<deletedAxiom>&apos;regulation of cell communication&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;cell communication&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cell communication&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cell communication&apos; SubClassOf &apos;regulates&apos; some &apos;cell communication&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CARO_0001010</classIRI>
<classLabel>organism or virus or viroid</classLabel>
<deletedAxiom>&apos;organism or virus or viroid&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043085</classIRI>
<classLabel>positive regulation of catalytic activity</classLabel>
<deletedAxiom>&apos;positive regulation of catalytic activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;catalytic activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of catalytic activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of catalytic activity&apos; SubClassOf &apos;positive regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of catalytic activity&apos; SubClassOf &apos;regulation of catalytic activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043086</classIRI>
<classLabel>negative regulation of catalytic activity</classLabel>
<deletedAxiom>&apos;negative regulation of catalytic activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;catalytic activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of catalytic activity&apos; SubClassOf &apos;regulation of catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of catalytic activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of catalytic activity&apos; SubClassOf &apos;negative regulation of molecular function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005623</classIRI>
<classLabel>cell</classLabel>
<deletedAxiom>&apos;cell&apos; SubClassOf &apos;cellular_component&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0023057</classIRI>
<classLabel>negative regulation of signaling</classLabel>
<deletedAxiom>&apos;negative regulation of signaling&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signaling&apos; SubClassOf &apos;regulation of signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signaling&apos; SubClassOf &apos;negatively regulates&apos; some &apos;signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signaling&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;signaling&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0023056</classIRI>
<classLabel>positive regulation of signaling</classLabel>
<deletedAxiom>&apos;positive regulation of signaling&apos; SubClassOf &apos;regulation of signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signaling&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;signaling&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signaling&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signaling&apos; SubClassOf &apos;positively regulates&apos; some &apos;signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0023052</classIRI>
<classLabel>signaling</classLabel>
<deletedAxiom>&apos;signaling&apos; SubClassOf &apos;biological_process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0023051</classIRI>
<classLabel>regulation of signaling</classLabel>
<deletedAxiom>&apos;regulation of signaling&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;signaling&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of signaling&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of signaling&apos; SubClassOf &apos;regulates&apos; some &apos;signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016301</classIRI>
<classLabel>kinase activity</classLabel>
<deletedAxiom>&apos;kinase activity&apos; SubClassOf &apos;part of&apos; some &apos;phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042995</classIRI>
<classLabel>cell projection</classLabel>
<deletedAxiom>&apos;cell projection&apos; SubClassOf &apos;cell part&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005102</classIRI>
<classLabel>signaling receptor binding</classLabel>
<deletedAxiom>&apos;signaling receptor binding&apos; SubClassOf &apos;protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038023</classIRI>
<classLabel>signaling receptor activity</classLabel>
<deletedAxiom>&apos;signaling receptor activity&apos; SubClassOf &apos;molecular transducer activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009966</classIRI>
<classLabel>regulation of signal transduction</classLabel>
<deletedAxiom>&apos;regulation of signal transduction&apos; SubClassOf &apos;regulates&apos; some &apos;signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of signal transduction&apos; SubClassOf &apos;regulation of cell communication&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of signal transduction&apos; SubClassOf &apos;regulation of response to stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of signal transduction&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;signal transduction&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of signal transduction&apos; SubClassOf &apos;regulation of signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009967</classIRI>
<classLabel>positive regulation of signal transduction</classLabel>
<deletedAxiom>&apos;positive regulation of signal transduction&apos; SubClassOf &apos;positively regulates&apos; some &apos;signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signal transduction&apos; SubClassOf &apos;regulation of signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signal transduction&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;signal transduction&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signal transduction&apos; SubClassOf &apos;positive regulation of signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signal transduction&apos; SubClassOf &apos;positive regulation of response to stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signal transduction&apos; SubClassOf &apos;positive regulation of cell communication&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009968</classIRI>
<classLabel>negative regulation of signal transduction</classLabel>
<deletedAxiom>&apos;negative regulation of signal transduction&apos; SubClassOf &apos;negative regulation of cell communication&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signal transduction&apos; SubClassOf &apos;negative regulation of signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signal transduction&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;signal transduction&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signal transduction&apos; SubClassOf &apos;negatively regulates&apos; some &apos;signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signal transduction&apos; SubClassOf &apos;regulation of signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of signal transduction&apos; SubClassOf &apos;negative regulation of response to stimulus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030545</classIRI>
<classLabel>receptor regulator activity</classLabel>
<deletedAxiom>&apos;receptor regulator activity&apos; SubClassOf &apos;molecular function regulator&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030546</classIRI>
<classLabel>signaling receptor activator activity</classLabel>
<deletedAxiom>&apos;signaling receptor activator activity&apos; SubClassOf &apos;receptor regulator activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009987</classIRI>
<classLabel>cellular process</classLabel>
<deletedAxiom>&apos;cellular process&apos; SubClassOf &apos;biological_process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051098</classIRI>
<classLabel>regulation of binding</classLabel>
<deletedAxiom>&apos;regulation of binding&apos; SubClassOf &apos;regulates&apos; some &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of binding&apos; SubClassOf &apos;regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051099</classIRI>
<classLabel>positive regulation of binding</classLabel>
<deletedAxiom>&apos;positive regulation of binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of binding&apos; SubClassOf &apos;regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of binding&apos; SubClassOf &apos;positive regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0040001</classIRI>
<classLabel>ring-shaped</classLabel>
<deletedAxiom>&apos;ring-shaped&apos; SubClassOf &apos;elliptic&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033673</classIRI>
<classLabel>negative regulation of kinase activity</classLabel>
<deletedAxiom>&apos;negative regulation of kinase activity&apos; SubClassOf &apos;negative regulation of phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of kinase activity&apos; SubClassOf &apos;regulation of kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of kinase activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of kinase activity&apos; SubClassOf &apos;negative regulation of transferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of kinase activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;kinase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033674</classIRI>
<classLabel>positive regulation of kinase activity</classLabel>
<deletedAxiom>&apos;positive regulation of kinase activity&apos; SubClassOf &apos;positive regulation of phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of kinase activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of kinase activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of kinase activity&apos; SubClassOf &apos;positive regulation of transferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of kinase activity&apos; SubClassOf &apos;regulation of kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010562</classIRI>
<classLabel>positive regulation of phosphorus metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of phosphorus metabolic process&apos; SubClassOf &apos;positively regulates&apos; some &apos;phosphorus metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of phosphorus metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of phosphorus metabolic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;phosphorus metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of phosphorus metabolic process&apos; SubClassOf &apos;regulation of phosphorus metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010563</classIRI>
<classLabel>negative regulation of phosphorus metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of phosphorus metabolic process&apos; SubClassOf &apos;negatively regulates&apos; some &apos;phosphorus metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphorus metabolic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;phosphorus metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphorus metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphorus metabolic process&apos; SubClassOf &apos;regulation of phosphorus metabolic process&apos;</deletedAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0040030</classIRI>
<classLabel>decreased width and length</classLabel>
<newAxiom>'decreased width and length' SubClassOf 'decreased length'</newAxiom>
<newAxiom>'decreased width and length' SubClassOf 'decreased width'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0040033</classIRI>
<classLabel>decreased linear velocity</classLabel>
<newAxiom>'decreased linear velocity' SubClassOf 'decreased process quality'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0040031</classIRI>
<classLabel>increased width and length</classLabel>
<newAxiom>'increased width and length' SubClassOf 'increased length'</newAxiom>
<newAxiom>'increased width and length' SubClassOf 'increased width'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0040032</classIRI>
<classLabel>increased linear velocity</classLabel>
<newAxiom>'increased linear velocity' SubClassOf 'increased process quality'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043393</classIRI>
<classLabel>regulation of protein binding</classLabel>
<newAxiom>'regulation of protein binding' SubClassOf 'regulation of binding'</newAxiom>
<newAxiom>'regulation of protein binding' SubClassOf 'regulates' some 'protein binding'</newAxiom>
<newAxiom>'regulation of protein binding' EquivalentTo 'biological_process' and ('regulates' some 'protein binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010469</classIRI>
<classLabel>regulation of signaling receptor activity</classLabel>
<newAxiom>'regulation of signaling receptor activity' SubClassOf 'regulates' some 'signaling receptor activity'</newAxiom>
<newAxiom>'regulation of signaling receptor activity' SubClassOf 'regulation of molecular function'</newAxiom>
<newAxiom>'regulation of signaling receptor activity' SubClassOf 'regulation of signal transduction'</newAxiom>
<newAxiom>'regulation of signaling receptor activity' EquivalentTo 'biological_process' and ('regulates' some 'signaling receptor activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008152</classIRI>
<classLabel>metabolic process</classLabel>
<newAxiom>'metabolic process' SubClassOf 'biological_process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044237</classIRI>
<classLabel>cellular metabolic process</classLabel>
<newAxiom>'cellular metabolic process' SubClassOf 'metabolic process'</newAxiom>
<newAxiom>'cellular metabolic process' SubClassOf 'cellular process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/CARO_0000014</classIRI>
<classLabel>cell part</classLabel>
<newAxiom>'cell part' SubClassOf 'connected anatomical structure'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900120</classIRI>
<classLabel>regulation of receptor binding</classLabel>
<newAxiom>'regulation of receptor binding' SubClassOf 'regulates' some 'signaling receptor binding'</newAxiom>
<newAxiom>'regulation of receptor binding' SubClassOf 'regulation of protein binding'</newAxiom>
<newAxiom>'regulation of receptor binding' EquivalentTo 'biological_process' and ('regulates' some 'signaling receptor binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900121</classIRI>
<classLabel>negative regulation of receptor binding</classLabel>
<newAxiom>'negative regulation of receptor binding' SubClassOf 'negative regulation of protein binding'</newAxiom>
<newAxiom>'negative regulation of receptor binding' SubClassOf 'regulation of receptor binding'</newAxiom>
<newAxiom>'negative regulation of receptor binding' EquivalentTo 'biological_process' and ('negatively regulates' some 'signaling receptor binding')</newAxiom>
<newAxiom>'negative regulation of receptor binding' SubClassOf 'negatively regulates' some 'signaling receptor binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900122</classIRI>
<classLabel>positive regulation of receptor binding</classLabel>
<newAxiom>'positive regulation of receptor binding' SubClassOf 'positive regulation of protein binding'</newAxiom>
<newAxiom>'positive regulation of receptor binding' EquivalentTo 'biological_process' and ('positively regulates' some 'signaling receptor binding')</newAxiom>
<newAxiom>'positive regulation of receptor binding' SubClassOf 'positively regulates' some 'signaling receptor binding'</newAxiom>
<newAxiom>'positive regulation of receptor binding' SubClassOf 'regulation of receptor binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005515</classIRI>
<classLabel>protein binding</classLabel>
<newAxiom>'protein binding' SubClassOf 'binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000273</classIRI>
<classLabel>positive regulation of signaling receptor activity</classLabel>
<newAxiom>'positive regulation of signaling receptor activity' SubClassOf 'positive regulation of molecular function'</newAxiom>
<newAxiom>'positive regulation of signaling receptor activity' EquivalentTo 'biological_process' and ('positively regulates' some 'signaling receptor activity')</newAxiom>
<newAxiom>'positive regulation of signaling receptor activity' SubClassOf 'regulation of signaling receptor activity'</newAxiom>
<newAxiom>'positive regulation of signaling receptor activity' SubClassOf 'positively regulates' some 'signaling receptor activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000272</classIRI>
<classLabel>negative regulation of signaling receptor activity</classLabel>
<newAxiom>'negative regulation of signaling receptor activity' SubClassOf 'negatively regulates' some 'signaling receptor activity'</newAxiom>
<newAxiom>'negative regulation of signaling receptor activity' SubClassOf 'negative regulation of molecular function'</newAxiom>
<newAxiom>'negative regulation of signaling receptor activity' SubClassOf 'regulation of signaling receptor activity'</newAxiom>
<newAxiom>'negative regulation of signaling receptor activity' EquivalentTo 'biological_process' and ('negatively regulates' some 'signaling receptor activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006793</classIRI>
<classLabel>phosphorus metabolic process</classLabel>
<newAxiom>'phosphorus metabolic process' SubClassOf 'cellular metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/RO_0002577</classIRI>
<classLabel>system</classLabel>
<newAxiom>'system' SubClassOf 'material entity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006796</classIRI>
<classLabel>phosphate-containing compound metabolic process</classLabel>
<newAxiom>'phosphate-containing compound metabolic process' SubClassOf 'phosphorus metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051338</classIRI>
<classLabel>regulation of transferase activity</classLabel>
<newAxiom>'regulation of transferase activity' EquivalentTo 'biological_process' and ('regulates' some 'transferase activity')</newAxiom>
<newAxiom>'regulation of transferase activity' SubClassOf 'regulation of catalytic activity'</newAxiom>
<newAxiom>'regulation of transferase activity' SubClassOf 'regulates' some 'transferase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005488</classIRI>
<classLabel>binding</classLabel>
<newAxiom>'binding' SubClassOf 'molecular_function'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051348</classIRI>
<classLabel>negative regulation of transferase activity</classLabel>
<newAxiom>'negative regulation of transferase activity' EquivalentTo 'biological_process' and ('negatively regulates' some 'transferase activity')</newAxiom>
<newAxiom>'negative regulation of transferase activity' SubClassOf 'regulation of transferase activity'</newAxiom>
<newAxiom>'negative regulation of transferase activity' SubClassOf 'negatively regulates' some 'transferase activity'</newAxiom>
<newAxiom>'negative regulation of transferase activity' SubClassOf 'negative regulation of catalytic activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051347</classIRI>
<classLabel>positive regulation of transferase activity</classLabel>
<newAxiom>'positive regulation of transferase activity' SubClassOf 'positive regulation of catalytic activity'</newAxiom>
<newAxiom>'positive regulation of transferase activity' SubClassOf 'positively regulates' some 'transferase activity'</newAxiom>
<newAxiom>'positive regulation of transferase activity' EquivalentTo 'biological_process' and ('positively regulates' some 'transferase activity')</newAxiom>
<newAxiom>'positive regulation of transferase activity' SubClassOf 'regulation of transferase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045936</classIRI>
<classLabel>negative regulation of phosphate metabolic process</classLabel>
<newAxiom>'negative regulation of phosphate metabolic process' SubClassOf 'negative regulation of phosphorus metabolic process'</newAxiom>
<newAxiom>'negative regulation of phosphate metabolic process' SubClassOf 'regulation of phosphate metabolic process'</newAxiom>
<newAxiom>'negative regulation of phosphate metabolic process' EquivalentTo 'biological_process' and ('negatively regulates' some 'phosphate-containing compound metabolic process')</newAxiom>
<newAxiom>'negative regulation of phosphate metabolic process' SubClassOf 'negatively regulates' some 'phosphate-containing compound metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045937</classIRI>
<classLabel>positive regulation of phosphate metabolic process</classLabel>
<newAxiom>'positive regulation of phosphate metabolic process' SubClassOf 'positively regulates' some 'phosphate-containing compound metabolic process'</newAxiom>
<newAxiom>'positive regulation of phosphate metabolic process' SubClassOf 'regulation of phosphate metabolic process'</newAxiom>
<newAxiom>'positive regulation of phosphate metabolic process' EquivalentTo 'biological_process' and ('positively regulates' some 'phosphate-containing compound metabolic process')</newAxiom>
<newAxiom>'positive regulation of phosphate metabolic process' SubClassOf 'positive regulation of phosphorus metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031324</classIRI>
<classLabel>negative regulation of cellular metabolic process</classLabel>
<newAxiom>'negative regulation of cellular metabolic process' SubClassOf 'negative regulation of cellular process'</newAxiom>
<newAxiom>'negative regulation of cellular metabolic process' SubClassOf 'regulation of cellular metabolic process'</newAxiom>
<newAxiom>'negative regulation of cellular metabolic process' SubClassOf 'negatively regulates' some 'cellular metabolic process'</newAxiom>
<newAxiom>'negative regulation of cellular metabolic process' EquivalentTo 'biological_process' and ('negatively regulates' some 'cellular metabolic process')</newAxiom>
<newAxiom>'negative regulation of cellular metabolic process' SubClassOf 'negative regulation of metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031323</classIRI>
<classLabel>regulation of cellular metabolic process</classLabel>
<newAxiom>'regulation of cellular metabolic process' SubClassOf 'regulation of cellular process'</newAxiom>
<newAxiom>'regulation of cellular metabolic process' EquivalentTo 'biological_process' and ('regulates' some 'cellular metabolic process')</newAxiom>
<newAxiom>'regulation of cellular metabolic process' SubClassOf 'regulation of metabolic process'</newAxiom>
<newAxiom>'regulation of cellular metabolic process' SubClassOf 'regulates' some 'cellular metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031325</classIRI>
<classLabel>positive regulation of cellular metabolic process</classLabel>
<newAxiom>'positive regulation of cellular metabolic process' EquivalentTo 'biological_process' and ('positively regulates' some 'cellular metabolic process')</newAxiom>
<newAxiom>'positive regulation of cellular metabolic process' SubClassOf 'positively regulates' some 'cellular metabolic process'</newAxiom>
<newAxiom>'positive regulation of cellular metabolic process' SubClassOf 'regulation of cellular metabolic process'</newAxiom>
<newAxiom>'positive regulation of cellular metabolic process' SubClassOf 'positive regulation of metabolic process'</newAxiom>
<newAxiom>'positive regulation of cellular metabolic process' SubClassOf 'positive regulation of cellular process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009892</classIRI>
<classLabel>negative regulation of metabolic process</classLabel>
<newAxiom>'negative regulation of metabolic process' SubClassOf 'regulation of metabolic process'</newAxiom>
<newAxiom>'negative regulation of metabolic process' SubClassOf 'negative regulation of biological process'</newAxiom>
<newAxiom>'negative regulation of metabolic process' SubClassOf 'negatively regulates' some 'metabolic process'</newAxiom>
<newAxiom>'negative regulation of metabolic process' EquivalentTo 'biological_process' and ('negatively regulates' some 'metabolic process')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000141</classIRI>
<classLabel>immaterial entity</classLabel>
<newAxiom>'immaterial entity' SubClassOf 'independent continuant'</newAxiom>
<newAxiom>'immaterial entity' DisjointWith 'has_part' some 'material entity'</newAxiom>
<newAxiom>'material entity' DisjointWith 'immaterial entity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009893</classIRI>
<classLabel>positive regulation of metabolic process</classLabel>
<newAxiom>'positive regulation of metabolic process' EquivalentTo 'biological_process' and ('positively regulates' some 'metabolic process')</newAxiom>
<newAxiom>'positive regulation of metabolic process' SubClassOf 'positively regulates' some 'metabolic process'</newAxiom>
<newAxiom>'positive regulation of metabolic process' SubClassOf 'positive regulation of biological process'</newAxiom>
<newAxiom>'positive regulation of metabolic process' SubClassOf 'regulation of metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019220</classIRI>
<classLabel>regulation of phosphate metabolic process</classLabel>
<newAxiom>'regulation of phosphate metabolic process' EquivalentTo 'biological_process' and ('regulates' some 'phosphate-containing compound metabolic process')</newAxiom>
<newAxiom>'regulation of phosphate metabolic process' SubClassOf 'regulation of phosphorus metabolic process'</newAxiom>
<newAxiom>'regulation of phosphate metabolic process' SubClassOf 'regulates' some 'phosphate-containing compound metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019222</classIRI>
<classLabel>regulation of metabolic process</classLabel>
<newAxiom>'regulation of metabolic process' EquivalentTo 'biological_process' and ('regulates' some 'metabolic process')</newAxiom>
<newAxiom>'regulation of metabolic process' SubClassOf 'regulation of biological process'</newAxiom>
<newAxiom>'regulation of metabolic process' SubClassOf 'regulates' some 'metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007165</classIRI>
<classLabel>signal transduction</classLabel>
<newAxiom>'signal transduction' SubClassOf 'part of' some 'cellular response to stimulus'</newAxiom>
<newAxiom>'signal transduction' SubClassOf 'regulation of cellular process'</newAxiom>
<newAxiom>'signal transduction' SubClassOf 'part of' some 'cell communication'</newAxiom>
<newAxiom>'signal transduction' SubClassOf 'part of' some 'signaling'</newAxiom>
<newAxiom>'signal transduction' SubClassOf 'cellular process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048522</classIRI>
<classLabel>positive regulation of cellular process</classLabel>
<newAxiom>'positive regulation of cellular process' EquivalentTo 'biological regulation' and ('positively regulates' some 'cellular process')</newAxiom>
<newAxiom>'positive regulation of cellular process' SubClassOf 'positively regulates' some 'cellular process'</newAxiom>
<newAxiom>'positive regulation of cellular process' SubClassOf 'positive regulation of biological process'</newAxiom>
<newAxiom>'positive regulation of cellular process' SubClassOf 'regulation of cellular process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048523</classIRI>
<classLabel>negative regulation of cellular process</classLabel>
<newAxiom>'negative regulation of cellular process' SubClassOf 'regulation of cellular process'</newAxiom>
<newAxiom>'negative regulation of cellular process' SubClassOf 'negatively regulates' some 'cellular process'</newAxiom>
<newAxiom>'negative regulation of cellular process' SubClassOf 'negative regulation of biological process'</newAxiom>
<newAxiom>'negative regulation of cellular process' EquivalentTo 'biological_process' and ('negatively regulates' some 'cellular process')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048518</classIRI>
<classLabel>positive regulation of biological process</classLabel>
<newAxiom>'positive regulation of biological process' SubClassOf 'regulation of biological process'</newAxiom>
<newAxiom>'positive regulation of biological process' EquivalentTo 'biological_process' and ('positively regulates' some 'biological_process')</newAxiom>
<newAxiom>'positive regulation of biological process' SubClassOf 'positively regulates' some 'biological_process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048519</classIRI>
<classLabel>negative regulation of biological process</classLabel>
<newAxiom>'negative regulation of biological process' EquivalentTo 'biological_process' and ('negatively regulates' some 'biological_process')</newAxiom>
<newAxiom>'negative regulation of biological process' SubClassOf 'negatively regulates' some 'biological_process'</newAxiom>
<newAxiom>'negative regulation of biological process' SubClassOf 'regulation of biological process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051716</classIRI>
<classLabel>cellular response to stimulus</classLabel>
<newAxiom>'cellular response to stimulus' SubClassOf 'response to stimulus'</newAxiom>
<newAxiom>'cellular response to stimulus' SubClassOf 'cellular process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048585</classIRI>
<classLabel>negative regulation of response to stimulus</classLabel>
<newAxiom>'negative regulation of response to stimulus' EquivalentTo 'biological_process' and ('negatively regulates' some 'response to stimulus')</newAxiom>
<newAxiom>'negative regulation of response to stimulus' SubClassOf 'negative regulation of biological process'</newAxiom>
<newAxiom>'negative regulation of response to stimulus' SubClassOf 'negatively regulates' some 'response to stimulus'</newAxiom>
<newAxiom>'negative regulation of response to stimulus' SubClassOf 'regulation of response to stimulus'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048583</classIRI>
<classLabel>regulation of response to stimulus</classLabel>
<newAxiom>'regulation of response to stimulus' EquivalentTo 'biological_process' and ('regulates' some 'response to stimulus')</newAxiom>
<newAxiom>'regulation of response to stimulus' SubClassOf 'regulation of biological process'</newAxiom>
<newAxiom>'regulation of response to stimulus' SubClassOf 'regulates' some 'response to stimulus'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048584</classIRI>
<classLabel>positive regulation of response to stimulus</classLabel>
<newAxiom>'positive regulation of response to stimulus' SubClassOf 'regulation of response to stimulus'</newAxiom>
<newAxiom>'positive regulation of response to stimulus' SubClassOf 'positively regulates' some 'response to stimulus'</newAxiom>
<newAxiom>'positive regulation of response to stimulus' SubClassOf 'positive regulation of biological process'</newAxiom>
<newAxiom>'positive regulation of response to stimulus' EquivalentTo 'biological_process' and ('positively regulates' some 'response to stimulus')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050896</classIRI>
<classLabel>response to stimulus</classLabel>
<newAxiom>'response to stimulus' SubClassOf 'biological_process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098772</classIRI>
<classLabel>molecular function regulator</classLabel>
<newAxiom>'molecular function regulator' SubClassOf 'molecular_function'</newAxiom>
<newAxiom>'molecular function regulator' SubClassOf 'part of' some 'regulation of molecular function'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048018</classIRI>
<classLabel>receptor ligand activity</classLabel>
<newAxiom>'receptor ligand activity' SubClassOf 'signaling receptor binding'</newAxiom>
<newAxiom>'receptor ligand activity' SubClassOf 'part of' some 'signal transduction'</newAxiom>
<newAxiom>'receptor ligand activity' SubClassOf 'signaling receptor activator activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000006</classIRI>
<classLabel>spatial region</classLabel>
<newAxiom>'spatial region' SubClassOf 'immaterial entity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000031</classIRI>
<classLabel>generically dependent continuant</classLabel>
<newAxiom>'independent continuant' DisjointWith 'generically dependent continuant'</newAxiom>
<newAxiom>'specifically dependent continuant' DisjointWith 'generically dependent continuant'</newAxiom>
<newAxiom>'generically dependent continuant' SubClassOf 'continuant'</newAxiom>
<newAxiom>'generically dependent continuant' SubClassOf 'part of' only 'generically dependent continuant'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000017</classIRI>
<classLabel>realizable entity</classLabel>
<newAxiom>'realizable entity' SubClassOf 'part of' only 'realizable entity'</newAxiom>
<newAxiom>'realizable entity' SubClassOf 'specifically dependent continuant'</newAxiom>
<newAxiom>'realizable entity' DisjointWith 'quality'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042327</classIRI>
<classLabel>positive regulation of phosphorylation</classLabel>
<newAxiom>'positive regulation of phosphorylation' SubClassOf 'positive regulation of phosphate metabolic process'</newAxiom>
<newAxiom>'positive regulation of phosphorylation' EquivalentTo 'biological_process' and ('positively regulates' some 'phosphorylation')</newAxiom>
<newAxiom>'positive regulation of phosphorylation' SubClassOf 'regulation of phosphorylation'</newAxiom>
<newAxiom>'positive regulation of phosphorylation' SubClassOf 'positively regulates' some 'phosphorylation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042326</classIRI>
<classLabel>negative regulation of phosphorylation</classLabel>
<newAxiom>'negative regulation of phosphorylation' SubClassOf 'negative regulation of phosphate metabolic process'</newAxiom>
<newAxiom>'negative regulation of phosphorylation' SubClassOf 'negatively regulates' some 'phosphorylation'</newAxiom>
<newAxiom>'negative regulation of phosphorylation' EquivalentTo 'biological_process' and ('negatively regulates' some 'phosphorylation')</newAxiom>
<newAxiom>'negative regulation of phosphorylation' SubClassOf 'regulation of phosphorylation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042325</classIRI>
<classLabel>regulation of phosphorylation</classLabel>
<newAxiom>'regulation of phosphorylation' SubClassOf 'regulation of phosphate metabolic process'</newAxiom>
<newAxiom>'regulation of phosphorylation' EquivalentTo 'biological_process' and ('regulates' some 'phosphorylation')</newAxiom>
<newAxiom>'regulation of phosphorylation' SubClassOf 'regulates' some 'phosphorylation'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0065009</classIRI>
<classLabel>regulation of molecular function</classLabel>
<newAxiom>'regulation of molecular function' SubClassOf 'regulates' some 'molecular_function'</newAxiom>
<newAxiom>'regulation of molecular function' SubClassOf 'biological regulation'</newAxiom>
<newAxiom>'regulation of molecular function' EquivalentTo 'biological_process' and ('regulates' some 'molecular_function')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0065007</classIRI>
<classLabel>biological regulation</classLabel>
<newAxiom>'biological regulation' SubClassOf 'biological_process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007154</classIRI>
<classLabel>cell communication</classLabel>
<newAxiom>'cell communication' SubClassOf 'cellular process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://www.w3.org/2002/07/owl#Nothing</classIRI>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035556</classIRI>
<classLabel>intracellular signal transduction</classLabel>
<newAxiom>'intracellular signal transduction' SubClassOf 'occurs in' some 'intracellular'</newAxiom>
<newAxiom>'intracellular signal transduction' EquivalentTo 'signal transduction' and ('occurs in' some 'intracellular')</newAxiom>
<newAxiom>'intracellular signal transduction' SubClassOf 'signal transduction'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004872</classIRI>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032091</classIRI>
<classLabel>negative regulation of protein binding</classLabel>
<newAxiom>'negative regulation of protein binding' EquivalentTo 'biological_process' and ('negatively regulates' some 'protein binding')</newAxiom>
<newAxiom>'negative regulation of protein binding' SubClassOf 'negative regulation of binding'</newAxiom>
<newAxiom>'negative regulation of protein binding' SubClassOf 'regulation of protein binding'</newAxiom>
<newAxiom>'negative regulation of protein binding' SubClassOf 'negatively regulates' some 'protein binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032092</classIRI>
<classLabel>positive regulation of protein binding</classLabel>
<newAxiom>'positive regulation of protein binding' SubClassOf 'regulation of protein binding'</newAxiom>
<newAxiom>'positive regulation of protein binding' SubClassOf 'positive regulation of binding'</newAxiom>
<newAxiom>'positive regulation of protein binding' SubClassOf 'positively regulates' some 'protein binding'</newAxiom>
<newAxiom>'positive regulation of protein binding' EquivalentTo 'biological_process' and ('positively regulates' some 'protein binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050789</classIRI>
<classLabel>regulation of biological process</classLabel>
<newAxiom>'regulation of biological process' SubClassOf 'biological regulation'</newAxiom>
<newAxiom>'regulation of biological process' EquivalentTo 'biological_process' and ('regulates' some 'biological_process')</newAxiom>
<newAxiom>'regulation of biological process' SubClassOf 'regulates' some 'biological_process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050790</classIRI>
<classLabel>regulation of catalytic activity</classLabel>
<newAxiom>'regulation of catalytic activity' SubClassOf 'regulates' some 'catalytic activity'</newAxiom>
<newAxiom>'regulation of catalytic activity' SubClassOf 'regulation of molecular function'</newAxiom>
<newAxiom>'regulation of catalytic activity' EquivalentTo 'biological_process' and ('regulates' some 'catalytic activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050794</classIRI>
<classLabel>regulation of cellular process</classLabel>
<newAxiom>'regulation of cellular process' SubClassOf 'regulation of biological process'</newAxiom>
<newAxiom>'regulation of cellular process' EquivalentTo 'biological regulation' and ('regulates' some 'cellular process')</newAxiom>
<newAxiom>'regulation of cellular process' SubClassOf 'regulates' some 'cellular process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044092</classIRI>
<classLabel>negative regulation of molecular function</classLabel>
<newAxiom>'negative regulation of molecular function' SubClassOf 'negatively regulates' some 'molecular_function'</newAxiom>
<newAxiom>'negative regulation of molecular function' SubClassOf 'regulation of molecular function'</newAxiom>
<newAxiom>'negative regulation of molecular function' EquivalentTo 'biological_process' and ('negatively regulates' some 'molecular_function')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044093</classIRI>
<classLabel>positive regulation of molecular function</classLabel>
<newAxiom>'positive regulation of molecular function' SubClassOf 'positively regulates' some 'molecular_function'</newAxiom>
<newAxiom>'positive regulation of molecular function' EquivalentTo 'biological_process' and ('positively regulates' some 'molecular_function')</newAxiom>
<newAxiom>'positive regulation of molecular function' SubClassOf 'regulation of molecular function'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902531</classIRI>
<classLabel>regulation of intracellular signal transduction</classLabel>
<newAxiom>'regulation of intracellular signal transduction' EquivalentTo 'biological_process' and ('regulates' some 'intracellular signal transduction')</newAxiom>
<newAxiom>'regulation of intracellular signal transduction' SubClassOf 'regulates' some 'intracellular signal transduction'</newAxiom>
<newAxiom>'regulation of intracellular signal transduction' SubClassOf 'regulation of signal transduction'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902533</classIRI>
<classLabel>positive regulation of intracellular signal transduction</classLabel>
<newAxiom>'positive regulation of intracellular signal transduction' SubClassOf 'regulation of intracellular signal transduction'</newAxiom>
<newAxiom>'positive regulation of intracellular signal transduction' EquivalentTo 'biological_process' and ('positively regulates' some 'intracellular signal transduction')</newAxiom>
<newAxiom>'positive regulation of intracellular signal transduction' SubClassOf 'positive regulation of signal transduction'</newAxiom>
<newAxiom>'positive regulation of intracellular signal transduction' SubClassOf 'positively regulates' some 'intracellular signal transduction'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902532</classIRI>
<classLabel>negative regulation of intracellular signal transduction</classLabel>
<newAxiom>'negative regulation of intracellular signal transduction' SubClassOf 'negatively regulates' some 'intracellular signal transduction'</newAxiom>
<newAxiom>'negative regulation of intracellular signal transduction' EquivalentTo 'biological_process' and ('negatively regulates' some 'intracellular signal transduction')</newAxiom>
<newAxiom>'negative regulation of intracellular signal transduction' SubClassOf 'regulation of intracellular signal transduction'</newAxiom>
<newAxiom>'negative regulation of intracellular signal transduction' SubClassOf 'negative regulation of signal transduction'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016310</classIRI>
<classLabel>phosphorylation</classLabel>
<newAxiom>'phosphorylation' SubClassOf 'phosphate-containing compound metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/ENVO_01000254</classIRI>
<classLabel>environmental system</classLabel>
<newAxiom>'environmental system' SubClassOf 'system'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051100</classIRI>
<classLabel>negative regulation of binding</classLabel>
<newAxiom>'negative regulation of binding' SubClassOf 'regulation of binding'</newAxiom>
<newAxiom>'negative regulation of binding' SubClassOf 'negatively regulates' some 'binding'</newAxiom>
<newAxiom>'negative regulation of binding' SubClassOf 'negative regulation of molecular function'</newAxiom>
<newAxiom>'negative regulation of binding' EquivalentTo 'biological_process' and ('negatively regulates' some 'binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051174</classIRI>
<classLabel>regulation of phosphorus metabolic process</classLabel>
<newAxiom>'regulation of phosphorus metabolic process' SubClassOf 'regulates' some 'phosphorus metabolic process'</newAxiom>
<newAxiom>'regulation of phosphorus metabolic process' SubClassOf 'regulation of cellular metabolic process'</newAxiom>
<newAxiom>'regulation of phosphorus metabolic process' EquivalentTo 'biological_process' and ('regulates' some 'phosphorus metabolic process')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060089</classIRI>
<classLabel>molecular transducer activity</classLabel>
<newAxiom>'molecular transducer activity' SubClassOf 'molecular_function'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043549</classIRI>
<classLabel>regulation of kinase activity</classLabel>
<newAxiom>'regulation of kinase activity' SubClassOf 'regulation of phosphorylation'</newAxiom>
<newAxiom>'regulation of kinase activity' SubClassOf 'regulates' some 'kinase activity'</newAxiom>
<newAxiom>'regulation of kinase activity' SubClassOf 'regulation of transferase activity'</newAxiom>
<newAxiom>'regulation of kinase activity' EquivalentTo 'biological_process' and ('regulates' some 'kinase activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010647</classIRI>
<classLabel>positive regulation of cell communication</classLabel>
<newAxiom>'positive regulation of cell communication' SubClassOf 'positive regulation of cellular process'</newAxiom>
<newAxiom>'positive regulation of cell communication' EquivalentTo 'biological_process' and ('positively regulates' some 'cell communication')</newAxiom>
<newAxiom>'positive regulation of cell communication' SubClassOf 'positively regulates' some 'cell communication'</newAxiom>
<newAxiom>'positive regulation of cell communication' SubClassOf 'regulation of cell communication'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010648</classIRI>
<classLabel>negative regulation of cell communication</classLabel>
<newAxiom>'negative regulation of cell communication' SubClassOf 'regulation of cell communication'</newAxiom>
<newAxiom>'negative regulation of cell communication' SubClassOf 'negatively regulates' some 'cell communication'</newAxiom>
<newAxiom>'negative regulation of cell communication' EquivalentTo 'biological_process' and ('negatively regulates' some 'cell communication')</newAxiom>
<newAxiom>'negative regulation of cell communication' SubClassOf 'negative regulation of cellular process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010646</classIRI>
<classLabel>regulation of cell communication</classLabel>
<newAxiom>'regulation of cell communication' EquivalentTo 'biological_process' and ('regulates' some 'cell communication')</newAxiom>
<newAxiom>'regulation of cell communication' SubClassOf 'regulation of cellular process'</newAxiom>
<newAxiom>'regulation of cell communication' SubClassOf 'regulates' some 'cell communication'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044424</classIRI>
<classLabel>obsolete intracellular part</classLabel>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/CARO_0001010</classIRI>
<classLabel>organism or virus or viroid</classLabel>
<newAxiom>'organism or virus or viroid' SubClassOf 'material entity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043085</classIRI>
<classLabel>positive regulation of catalytic activity</classLabel>
<newAxiom>'positive regulation of catalytic activity' EquivalentTo 'biological_process' and ('positively regulates' some 'catalytic activity')</newAxiom>
<newAxiom>'positive regulation of catalytic activity' SubClassOf 'positively regulates' some 'catalytic activity'</newAxiom>
<newAxiom>'positive regulation of catalytic activity' SubClassOf 'positive regulation of molecular function'</newAxiom>
<newAxiom>'positive regulation of catalytic activity' SubClassOf 'regulation of catalytic activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043086</classIRI>
<classLabel>negative regulation of catalytic activity</classLabel>
<newAxiom>'negative regulation of catalytic activity' EquivalentTo 'biological_process' and ('negatively regulates' some 'catalytic activity')</newAxiom>
<newAxiom>'negative regulation of catalytic activity' SubClassOf 'regulation of catalytic activity'</newAxiom>
<newAxiom>'negative regulation of catalytic activity' SubClassOf 'negatively regulates' some 'catalytic activity'</newAxiom>
<newAxiom>'negative regulation of catalytic activity' SubClassOf 'negative regulation of molecular function'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005623</classIRI>
<classLabel>cell</classLabel>
<newAxiom>'cell' SubClassOf 'cellular_component'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0023057</classIRI>
<classLabel>negative regulation of signaling</classLabel>
<newAxiom>'negative regulation of signaling' SubClassOf 'negative regulation of biological process'</newAxiom>
<newAxiom>'negative regulation of signaling' SubClassOf 'regulation of signaling'</newAxiom>
<newAxiom>'negative regulation of signaling' SubClassOf 'negatively regulates' some 'signaling'</newAxiom>
<newAxiom>'negative regulation of signaling' EquivalentTo 'biological_process' and ('negatively regulates' some 'signaling')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0023056</classIRI>
<classLabel>positive regulation of signaling</classLabel>
<newAxiom>'positive regulation of signaling' SubClassOf 'regulation of signaling'</newAxiom>
<newAxiom>'positive regulation of signaling' EquivalentTo 'biological_process' and ('positively regulates' some 'signaling')</newAxiom>
<newAxiom>'positive regulation of signaling' SubClassOf 'positive regulation of biological process'</newAxiom>
<newAxiom>'positive regulation of signaling' SubClassOf 'positively regulates' some 'signaling'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0023052</classIRI>
<classLabel>signaling</classLabel>
<newAxiom>'signaling' SubClassOf 'biological_process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0023051</classIRI>
<classLabel>regulation of signaling</classLabel>
<newAxiom>'regulation of signaling' EquivalentTo 'biological_process' and ('regulates' some 'signaling')</newAxiom>
<newAxiom>'regulation of signaling' SubClassOf 'regulation of biological process'</newAxiom>
<newAxiom>'regulation of signaling' SubClassOf 'regulates' some 'signaling'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005102</classIRI>
<classLabel>signaling receptor binding</classLabel>
<newAxiom>'signaling receptor binding' SubClassOf 'protein binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038023</classIRI>
<classLabel>signaling receptor activity</classLabel>
<newAxiom>'signaling receptor activity' SubClassOf 'molecular transducer activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009966</classIRI>
<classLabel>regulation of signal transduction</classLabel>
<newAxiom>'regulation of signal transduction' SubClassOf 'regulates' some 'signal transduction'</newAxiom>
<newAxiom>'regulation of signal transduction' SubClassOf 'regulation of cell communication'</newAxiom>
<newAxiom>'regulation of signal transduction' SubClassOf 'regulation of response to stimulus'</newAxiom>
<newAxiom>'regulation of signal transduction' EquivalentTo 'biological_process' and ('regulates' some 'signal transduction')</newAxiom>
<newAxiom>'regulation of signal transduction' SubClassOf 'regulation of signaling'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009967</classIRI>
<classLabel>positive regulation of signal transduction</classLabel>
<newAxiom>'positive regulation of signal transduction' SubClassOf 'positively regulates' some 'signal transduction'</newAxiom>
<newAxiom>'positive regulation of signal transduction' SubClassOf 'regulation of signal transduction'</newAxiom>
<newAxiom>'positive regulation of signal transduction' EquivalentTo 'biological_process' and ('positively regulates' some 'signal transduction')</newAxiom>
<newAxiom>'positive regulation of signal transduction' SubClassOf 'positive regulation of signaling'</newAxiom>
<newAxiom>'positive regulation of signal transduction' SubClassOf 'positive regulation of response to stimulus'</newAxiom>
<newAxiom>'positive regulation of signal transduction' SubClassOf 'positive regulation of cell communication'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009968</classIRI>
<classLabel>negative regulation of signal transduction</classLabel>
<newAxiom>'negative regulation of signal transduction' SubClassOf 'negative regulation of cell communication'</newAxiom>
<newAxiom>'negative regulation of signal transduction' SubClassOf 'negative regulation of signaling'</newAxiom>
<newAxiom>'negative regulation of signal transduction' EquivalentTo 'biological_process' and ('negatively regulates' some 'signal transduction')</newAxiom>
<newAxiom>'negative regulation of signal transduction' SubClassOf 'negatively regulates' some 'signal transduction'</newAxiom>
<newAxiom>'negative regulation of signal transduction' SubClassOf 'regulation of signal transduction'</newAxiom>
<newAxiom>'negative regulation of signal transduction' SubClassOf 'negative regulation of response to stimulus'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030545</classIRI>
<classLabel>receptor regulator activity</classLabel>
<newAxiom>'receptor regulator activity' SubClassOf 'molecular function regulator'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030546</classIRI>
<classLabel>signaling receptor activator activity</classLabel>
<newAxiom>'signaling receptor activator activity' SubClassOf 'receptor regulator activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009987</classIRI>
<classLabel>cellular process</classLabel>
<newAxiom>'cellular process' SubClassOf 'biological_process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051098</classIRI>
<classLabel>regulation of binding</classLabel>
<newAxiom>'regulation of binding' SubClassOf 'regulates' some 'binding'</newAxiom>
<newAxiom>'regulation of binding' SubClassOf 'regulation of molecular function'</newAxiom>
<newAxiom>'regulation of binding' EquivalentTo 'biological_process' and ('regulates' some 'binding')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051099</classIRI>
<classLabel>positive regulation of binding</classLabel>
<newAxiom>'positive regulation of binding' EquivalentTo 'biological_process' and ('positively regulates' some 'binding')</newAxiom>
<newAxiom>'positive regulation of binding' SubClassOf 'regulation of binding'</newAxiom>
<newAxiom>'positive regulation of binding' SubClassOf 'positive regulation of molecular function'</newAxiom>
<newAxiom>'positive regulation of binding' SubClassOf 'positively regulates' some 'binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033673</classIRI>
<classLabel>negative regulation of kinase activity</classLabel>
<newAxiom>'negative regulation of kinase activity' SubClassOf 'negative regulation of phosphorylation'</newAxiom>
<newAxiom>'negative regulation of kinase activity' SubClassOf 'regulation of kinase activity'</newAxiom>
<newAxiom>'negative regulation of kinase activity' SubClassOf 'negatively regulates' some 'kinase activity'</newAxiom>
<newAxiom>'negative regulation of kinase activity' SubClassOf 'negative regulation of transferase activity'</newAxiom>
<newAxiom>'negative regulation of kinase activity' EquivalentTo 'biological_process' and ('negatively regulates' some 'kinase activity')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033674</classIRI>
<classLabel>positive regulation of kinase activity</classLabel>
<newAxiom>'positive regulation of kinase activity' SubClassOf 'positive regulation of phosphorylation'</newAxiom>
<newAxiom>'positive regulation of kinase activity' EquivalentTo 'biological_process' and ('positively regulates' some 'kinase activity')</newAxiom>
<newAxiom>'positive regulation of kinase activity' SubClassOf 'positively regulates' some 'kinase activity'</newAxiom>
<newAxiom>'positive regulation of kinase activity' SubClassOf 'positive regulation of transferase activity'</newAxiom>
<newAxiom>'positive regulation of kinase activity' SubClassOf 'regulation of kinase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010562</classIRI>
<classLabel>positive regulation of phosphorus metabolic process</classLabel>
<newAxiom>'positive regulation of phosphorus metabolic process' SubClassOf 'positively regulates' some 'phosphorus metabolic process'</newAxiom>
<newAxiom>'positive regulation of phosphorus metabolic process' SubClassOf 'positive regulation of cellular metabolic process'</newAxiom>
<newAxiom>'positive regulation of phosphorus metabolic process' EquivalentTo 'biological_process' and ('positively regulates' some 'phosphorus metabolic process')</newAxiom>
<newAxiom>'positive regulation of phosphorus metabolic process' SubClassOf 'regulation of phosphorus metabolic process'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010563</classIRI>
<classLabel>negative regulation of phosphorus metabolic process</classLabel>
<newAxiom>'negative regulation of phosphorus metabolic process' SubClassOf 'negatively regulates' some 'phosphorus metabolic process'</newAxiom>
<newAxiom>'negative regulation of phosphorus metabolic process' EquivalentTo 'biological_process' and ('negatively regulates' some 'phosphorus metabolic process')</newAxiom>
<newAxiom>'negative regulation of phosphorus metabolic process' SubClassOf 'negative regulation of cellular metabolic process'</newAxiom>
<newAxiom>'negative regulation of phosphorus metabolic process' SubClassOf 'regulation of phosphorus metabolic process'</newAxiom>
</deletedClass>
</deletedClasses>
</diffReport>