<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
244
</numberChangedClasses>
<numberNewClasses>
520
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C53270</classIRI>
<classLabel>Neutrophil Count 500</classLabel>
<deletedAxiom>&apos;Neutrophil Count 500&apos; SubClassOf &apos;Hematopoietic System Finding&apos;</deletedAxiom>
<newAxiom>&apos;Neutrophil Count 500&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158951</classIRI>
<classLabel>Ring Chromosome 12</classLabel>
<deletedAxiom>&apos;Ring Chromosome 12&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 21&apos;</deletedAxiom>
<newAxiom>&apos;Ring Chromosome 12&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 12&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3324</classIRI>
<classLabel>Peutz-Jeghers Syndrome</classLabel>
<deletedAxiom>&apos;Peutz-Jeghers Syndrome&apos; EquivalentTo &apos;Hereditary Neoplastic Syndrome&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;LKB1 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Pancreatic Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ovarian Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Small Intestinal Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Cervical Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Malignant Testicular Germ Cell Tumor&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Peutz-Jeghers Polyp&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;STK11 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Peutz-Jeghers Syndrome&apos; EquivalentTo &apos;Hereditary Neoplastic Syndrome&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;STK11 Gene Mutation&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162466) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Pancreatic Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ovarian Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Small Intestinal Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Cervical Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Malignant Testicular Germ Cell Tumor&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Peutz-Jeghers Polyp&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;STK11 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158781</classIRI>
<classLabel>Dedifferentiated Lesion</classLabel>
<deletedAxiom>&apos;Dedifferentiated Lesion&apos; SubClassOf &apos;Well Differentiated Lesion&apos;</deletedAxiom>
<newAxiom>&apos;Dedifferentiated Lesion&apos; SubClassOf &apos;Lesion by Morphology&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158729</classIRI>
<classLabel>GRPR Overexpression Positive</classLabel>
<newAxiom>&apos;GRPR Overexpression Positive&apos; SubClassOf &apos;Receptor Status&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158699</classIRI>
<classLabel>Per 10 High Powered Fields, or for GISTs</classLabel>
<deletedAxiom>&apos;Per 10 High Powered Fields, or for GISTs&apos; SubClassOf &apos;CPTAC Questions&apos;</deletedAxiom>
<newAxiom>&apos;Per 10 High Powered Fields, or for GISTs&apos; SubClassOf &apos;Per Visual Field&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3099</classIRI>
<classLabel>Hepatocellular Carcinoma</classLabel>
<deletedAxiom>&apos;Hepatocellular Carcinoma&apos; EquivalentTo &apos;Adenocarcinoma&apos; and &apos;Liver and Intrahepatic Bile Duct Carcinoma&apos; and &apos;Primary Carcinoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Liver&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Hepatic Tissue&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Hepatocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Adenocarcinoma Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 5q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 3&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 18&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 13q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 17p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 1p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 8p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 16q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome X&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 20&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 17&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 4q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 6&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 16&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 10&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Gamma-Glutamyltransferase Increased&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Aspartate Aminotransferase Increased&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Alanine Aminotransferase Increased&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Ascites&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Jaundice&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Alpha Fetoprotein Increased&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Mallory Bodies Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Monoclonal Hepatocyte Population Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Transforming Growth Factor-Beta Overexpression&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fibroblast Growth Factor 2 Overexpression&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fibroblast Growth Factor 1 Overexpression&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Malaise&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Intrahepatic Bile Duct&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CTNNB1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Aberrant DNA Methylation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PTEN Gene Inactivation&apos;)</deletedAxiom>
<newAxiom>&apos;Hepatocellular Carcinoma&apos; EquivalentTo &apos;Adenocarcinoma&apos; and &apos;Liver and Intrahepatic Bile Duct Carcinoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Liver&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Hepatic Tissue&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Hepatocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Adenocarcinoma Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 5q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 3&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 18&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 13q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 17p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 1p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 8p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 16q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome X&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 20&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 17&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 4q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 6&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 16&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 10&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Gamma-Glutamyltransferase Increased&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Aspartate Aminotransferase Increased&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Alanine Aminotransferase Increased&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Ascites&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Jaundice&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Alpha Fetoprotein Increased&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Mallory Bodies Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Monoclonal Hepatocyte Population Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Transforming Growth Factor-Beta Overexpression&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fibroblast Growth Factor 2 Overexpression&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fibroblast Growth Factor 1 Overexpression&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Malaise&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Intrahepatic Bile Duct&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CTNNB1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Aberrant DNA Methylation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PTEN Gene Inactivation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158819</classIRI>
<classLabel>Adenocarcinoma Solitary Lesion in situ of Lung</classLabel>
<deletedAxiom>&apos;Adenocarcinoma Solitary Lesion in situ of Lung&apos; SubClassOf &apos;Lesion&apos;</deletedAxiom>
<newAxiom>&apos;Adenocarcinoma Solitary Lesion in situ of Lung&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158867</classIRI>
<classLabel>Cell Source</classLabel>
<deletedAxiom>&apos;Cell Source&apos; SubClassOf &apos;Source&apos;</deletedAxiom>
<newAxiom>&apos;Cell Source&apos; SubClassOf &apos;CPTAC Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158847</classIRI>
<classLabel>Presence of Another Mutation</classLabel>
<deletedAxiom>&apos;Presence of Another Mutation&apos; SubClassOf &apos;CPTAC Questions&apos;</deletedAxiom>
<newAxiom>&apos;Presence of Another Mutation&apos; SubClassOf &apos;Were Molecular Abnormalities Detected&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158547</classIRI>
<classLabel>Clonal Hematopoiesis of Indeterminate Potential</classLabel>
<deletedAxiom>&apos;Clonal Hematopoiesis of Indeterminate Potential&apos; EquivalentTo &apos;Premalignant Hematologic Condition&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Somatic Mutation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Monoclonal Cellular Population Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Age-Related Clonal Hematopoiesis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cytopenia&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Malignant Cellular Infiltrate&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TET2 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;DNMT3A Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;ASXL1 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Clonal Hematopoiesis of Indeterminate Potential&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162188 and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Somatic Mutation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Age-Related Clonal Hematopoiesis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cytopenia&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Malignant Cellular Infiltrate&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TET2 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;DNMT3A Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;ASXL1 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3717</classIRI>
<classLabel>Melanotic Neuroectodermal Tumor</classLabel>
<deletedAxiom>&apos;Melanotic Neuroectodermal Tumor&apos; EquivalentTo &apos;Primitive Neuroectodermal Tumor&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Small Neuroepithelial Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Infantile Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Melanin-Forming Neuroepithelial Cells Present&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Neuroectodermal Small Cell&apos;)</deletedAxiom>
<newAxiom>&apos;Melanotic Neuroectodermal Tumor&apos; EquivalentTo &apos;Embryonal Neoplasm&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Neural Crest&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Small Neuroepithelial Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Infantile Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Melanin-Forming Neuroepithelial Cells Present&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Neuroectodermal Small Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158467</classIRI>
<classLabel>MUC1* Positive Cells Present</classLabel>
<newAxiom>&apos;MUC1* Positive Cells Present&apos; SubClassOf &apos;MUC1 Positive&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3861</classIRI>
<classLabel>Ependymal Tumor of Brain</classLabel>
<deletedAxiom>&apos;Ependymal Tumor of Brain&apos; EquivalentTo &apos;Primary Brain Neoplasm&apos; and &apos;Ependymal Tumor&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Ependyma&apos;)</deletedAxiom>
<newAxiom>&apos;Ependymal Tumor of Brain&apos; EquivalentTo &apos;Ependymal Tumor&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Ependyma&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150573</classIRI>
<classLabel>Primary Cerebral Neoplasm</classLabel>
<deletedAxiom>&apos;Primary Cerebral Neoplasm&apos; EquivalentTo &apos;Cerebral Neoplasm&apos; and &apos;Primary Brain Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cerebral Hemisphere&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Cerebral Neoplasm&apos; EquivalentTo &apos;Cerebral Neoplasm&apos; and &apos;Primary Brain Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cerebral Hemisphere&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150383</classIRI>
<classLabel>FGFR1/2/3 Inhibitor HMPL-453</classLabel>
<deletedAxiom>&apos;FGFR1/2/3 Inhibitor HMPL-453&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C93031</classIRI>
<classLabel>Paratesticular Soft Tissue</classLabel>
<newAxiom>&apos;Paratesticular Soft Tissue&apos; SubClassOf &apos;Anatomic_Structure_Is_Physical_Part_Of&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162491</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34850</classIRI>
<classLabel>Night Blindness</classLabel>
<newAxiom>&apos;Night Blindness&apos; SubClassOf &apos;Visual Manifestations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C139291</classIRI>
<classLabel>Advanced Head and Neck Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Advanced Head and Neck Squamous Cell Carcinoma&apos; EquivalentTo &apos;Advanced Head and Neck Carcinoma&apos; and &apos;Metastatic Head and Neck Squamous Cell Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Head and Neck Squamous Cell Carcinoma&apos; EquivalentTo &apos;Advanced Head and Neck Carcinoma&apos; and &apos;Metastatic Head and Neck Squamous Cell Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162653</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C139004</classIRI>
<classLabel>Pan-FGFR Inhibitor LY2874455</classLabel>
<deletedAxiom>&apos;Pan-FGFR Inhibitor LY2874455&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20917</classIRI>
<classLabel>Cell Cycle Gene</classLabel>
<newAxiom>&apos;Cell Cycle Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Cell Cycle Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40022</classIRI>
<classLabel>Primary Peritoneal Carcinoma</classLabel>
<deletedAxiom>&apos;Primary Peritoneal Carcinoma&apos; EquivalentTo &apos;Malignant Peritoneal Neoplasm&apos; and &apos;Primary Carcinoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Peritoneum&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Ovary&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Peritoneal Carcinoma&apos; EquivalentTo &apos;Carcinoma&apos; and &apos;Malignant Peritoneal Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Peritoneum&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Ovary&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143067</classIRI>
<classLabel>FGFR4 Antagonist INCB062079</classLabel>
<deletedAxiom>&apos;FGFR4 Antagonist INCB062079&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88272</classIRI>
<classLabel>FGFR Inhibitor AZD4547</classLabel>
<deletedAxiom>&apos;FGFR Inhibitor AZD4547&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143012</classIRI>
<classLabel>Recurrent Skin Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Recurrent Skin Squamous Cell Carcinoma&apos; EquivalentTo &apos;Skin Squamous Cell Carcinoma&apos; and &apos;Recurrent Skin Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Skin Squamous Cell Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162652 and &apos;Skin Squamous Cell Carcinoma&apos; and &apos;Recurrent Skin Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157438</classIRI>
<classLabel>First Degree Family History of Cancer</classLabel>
<deletedAxiom>&apos;First Degree Family History of Cancer&apos; SubClassOf &apos;Family Cancer History&apos;</deletedAxiom>
<newAxiom>&apos;First Degree Family History of Cancer&apos; SubClassOf &apos;CPTAC Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157440</classIRI>
<classLabel>First Degree Family History of Primary Brain Tumor</classLabel>
<deletedAxiom>&apos;First Degree Family History of Primary Brain Tumor&apos; SubClassOf &apos;Family Cancer History&apos;</deletedAxiom>
<newAxiom>&apos;First Degree Family History of Primary Brain Tumor&apos; SubClassOf &apos;CPTAC Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157441</classIRI>
<classLabel>Family History of Stomach Cancer</classLabel>
<deletedAxiom>&apos;Family History of Stomach Cancer&apos; SubClassOf &apos;Family Cancer History&apos;</deletedAxiom>
<newAxiom>&apos;Family History of Stomach Cancer&apos; SubClassOf &apos;CPTAC Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123826</classIRI>
<classLabel>FGFR4 Inhibitor BLU-554</classLabel>
<deletedAxiom>&apos;FGFR4 Inhibitor BLU-554&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157233</classIRI>
<classLabel>First Presenting Symptom Related to Disease</classLabel>
<deletedAxiom>&apos;First Presenting Symptom Related to Disease&apos; SubClassOf &apos;Form Directive&apos;</deletedAxiom>
<newAxiom>&apos;First Presenting Symptom Related to Disease&apos; SubClassOf &apos;CPTAC Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157162</classIRI>
<classLabel>Adjuvant I-131 Therapy</classLabel>
<deletedAxiom>&apos;Adjuvant I-131 Therapy&apos; SubClassOf &apos;Adjuvant Radiation Therapy&apos;</deletedAxiom>
<newAxiom>&apos;Adjuvant I-131 Therapy&apos; SubClassOf &apos;CPTAC Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157152</classIRI>
<classLabel>Radiation Exposure History</classLabel>
<deletedAxiom>&apos;Radiation Exposure History&apos; SubClassOf &apos;Chemical/Occupational Exposure History&apos;</deletedAxiom>
<newAxiom>&apos;Radiation Exposure History&apos; SubClassOf &apos;CPTAC Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157129</classIRI>
<classLabel>Locally Advanced Adrenal Gland Pheochromocytoma</classLabel>
<deletedAxiom>&apos;Locally Advanced Adrenal Gland Pheochromocytoma&apos; EquivalentTo &apos;Locally Advanced Paraganglioma&apos; and &apos;Regional Adrenal Gland Pheochromocytoma&apos; and &apos;Metastatic Adrenal Gland Pheochromocytoma&apos;</deletedAxiom>
<newAxiom>&apos;Locally Advanced Adrenal Gland Pheochromocytoma&apos; EquivalentTo &apos;Locally Advanced Paraganglioma&apos; and &apos;Metastatic Adrenal Gland Pheochromocytoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40996</classIRI>
<classLabel>CD14-Positive Neoplastic Cells Present</classLabel>
<newAxiom>&apos;CD14-Positive Neoplastic Cells Present&apos; SubClassOf &apos;CD14 Positive&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2194</classIRI>
<classLabel>Sorafenib Tosylate</classLabel>
<deletedAxiom>&apos;Sorafenib Tosylate&apos; SubClassOf &apos;Protein Kinase Inhibitor&apos;</deletedAxiom>
<deletedAxiom>&apos;Sorafenib Tosylate&apos; SubClassOf &apos;Angiogenesis Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Sorafenib Tosylate&apos; SubClassOf &apos;VEGFR Tyrosine Kinase Inhibitor&apos;</newAxiom>
<newAxiom>&apos;Sorafenib Tosylate&apos; SubClassOf &apos;PDGFR Inhibitor&apos;</newAxiom>
<newAxiom>&apos;Sorafenib Tosylate&apos; SubClassOf &apos;Raf Kinase Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124127</classIRI>
<classLabel>Protein Disulfide-Isomerase Family</classLabel>
<newAxiom>&apos;Protein Disulfide-Isomerase Family&apos; SubClassOf &apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Procollagen-Proline Dioxygenase&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C69080</classIRI>
<classLabel>CD5-Positive Neoplastic Cells Present</classLabel>
<newAxiom>&apos;CD5-Positive Neoplastic Cells Present&apos; SubClassOf &apos;CD5 Positive&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C69081</classIRI>
<classLabel>CD23-Positive Neoplastic Cells Present</classLabel>
<newAxiom>&apos;CD23-Positive Neoplastic Cells Present&apos; SubClassOf &apos;FCER2 Positive&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C60780</classIRI>
<classLabel>Brain Astrocytoma</classLabel>
<deletedAxiom>&apos;Brain Astrocytoma&apos; EquivalentTo &apos;Primary Brain Neoplasm&apos; and &apos;Astrocytoma&apos;</deletedAxiom>
<newAxiom>&apos;Brain Astrocytoma&apos; EquivalentTo &apos;Astrocytoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Brain&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C60707</classIRI>
<classLabel>Neuron-Specific Enolase Positive Neoplastic Cells Present</classLabel>
<newAxiom>&apos;Neuron-Specific Enolase Positive Neoplastic Cells Present&apos; SubClassOf &apos;NSE Positive&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138019</classIRI>
<classLabel>Recurrent Central Nervous System Lymphoma</classLabel>
<deletedAxiom>&apos;Recurrent Central Nervous System Lymphoma&apos; EquivalentTo &apos;Recurrent Primary Malignant Neoplasm&apos; and &apos;Recurrent Lymphoma&apos; and &apos;Recurrent Malignant Central Nervous System Neoplasm&apos; and &apos;Central Nervous System Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Central Nervous System Lymphoma&apos; EquivalentTo &apos;Recurrent Lymphoma&apos; and &apos;Recurrent Malignant Central Nervous System Neoplasm&apos; and &apos;Central Nervous System Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C94764</classIRI>
<classLabel>Diffuse Intrinsic Pontine Glioma</classLabel>
<deletedAxiom>&apos;Diffuse Intrinsic Pontine Glioma&apos; EquivalentTo &apos;Diffuse Midline Glioma, H3 K27M-Mutant&apos; and &apos;Malignant Brain Stem Neoplasm&apos; and &apos;Primary Malignant Brain Neoplasm&apos; and &apos;Malignant Childhood Central Nervous System Neoplasm&apos; and &apos;Childhood Brain Stem Glioma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Pons Varolii&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Unfavorable Clinical Outcome&apos;)</deletedAxiom>
<newAxiom>&apos;Diffuse Intrinsic Pontine Glioma&apos; EquivalentTo &apos;Diffuse Midline Glioma, H3 K27M-Mutant&apos; and &apos;Malignant Brain Stem Neoplasm&apos; and &apos;Malignant Childhood Central Nervous System Neoplasm&apos; and &apos;Childhood Brain Stem Glioma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Pons Varolii&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Unfavorable Clinical Outcome&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80699</classIRI>
<classLabel>MicroRNA Gene</classLabel>
<newAxiom>&apos;MicroRNA Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Gene Expression Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80824</classIRI>
<classLabel>Equine Thymocyte Immune Globulin</classLabel>
<newAxiom>&apos;Equine Thymocyte Immune Globulin&apos; SubClassOf &apos;Anti-Thymocyte Globulin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80833</classIRI>
<classLabel>Lapine T-Lymphocyte Immune Globulin</classLabel>
<newAxiom>&apos;Lapine T-Lymphocyte Immune Globulin&apos; SubClassOf &apos;Anti-Thymocyte Globulin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132889</classIRI>
<classLabel>MIR124-2 Pre-miRNA</classLabel>
<newAxiom>&apos;MIR124-2 Pre-miRNA&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;MIR124-2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5151</classIRI>
<classLabel>Cerebral Glioblastoma</classLabel>
<deletedAxiom>&apos;Cerebral Glioblastoma&apos; EquivalentTo &apos;Primary Cerebral Neoplasm&apos; and &apos;Malignant Cerebral Neoplasm&apos; and &apos;Supratentorial Glioblastoma&apos;</deletedAxiom>
<newAxiom>&apos;Cerebral Glioblastoma&apos; EquivalentTo &apos;Malignant Cerebral Neoplasm&apos; and &apos;Cerebral Neoplasm&apos; and &apos;Supratentorial Glioblastoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cerebral Hemisphere&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16687</classIRI>
<classLabel>Histone</classLabel>
<newAxiom>&apos;Histone&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Chromatin Structural Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36037</classIRI>
<classLabel>Non-Metastatic Neoplasm</classLabel>
<deletedAxiom>&apos;Non-Metastatic Neoplasm&apos; SubClassOf &apos;Neoplasm by Special Category&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Neoplasm&apos; EquivalentTo &apos;Neoplasm by Special Category&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C152972</classIRI>
<classLabel>CENPA Gene</classLabel>
<newAxiom>&apos;CENPA Gene&apos; SubClassOf &apos;Histone H3 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C152974</classIRI>
<classLabel>Histone H3-Like Centromeric Protein A</classLabel>
<deletedAxiom>&apos;Histone H3-Like Centromeric Protein A&apos; EquivalentTo &apos;Cell Cycle Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Aurora A Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Aurora B Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;FOXM1 Transcription Factor Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleosome&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cytosol&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Histone Fold&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cytokinesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Binding&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CENPA Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Histone H3-Like Centromeric Protein A&apos; EquivalentTo &apos;Histone H3&apos; and &apos;Cell Cycle Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Aurora A Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Aurora B Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;FOXM1 Transcription Factor Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Centromere&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleosome&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cytosol&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Histone Fold&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cytokinesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Binding&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CENPA Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95252</classIRI>
<classLabel>TET2 Gene</classLabel>
<deletedAxiom>&apos;TET2 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Oxidation/Reduction&apos;</deletedAxiom>
<newAxiom>&apos;TET2 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;DNA Methylation Regulation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95254</classIRI>
<classLabel>Methylcytosine Dioxygenase TET2</classLabel>
<deletedAxiom>&apos;Methylcytosine Dioxygenase TET2&apos; EquivalentTo &apos;Oxidoreductase&apos; and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Polycythemia Vera&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Proline-Rich Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Oxidation/Reduction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Nucleotide Metabolic Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Cycle Regulation Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Myelopoiesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Tumor Suppression&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TET2 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Methylcytosine Dioxygenase TET2&apos; EquivalentTo &apos;Oxidoreductase&apos; and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Polycythemia Vera&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Proline-Rich Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Oxidation/Reduction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Nucleotide Metabolic Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Cycle Regulation Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Myelopoiesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Tumor Suppression&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Methylation Regulation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TET2 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95423</classIRI>
<classLabel>TET1 Gene</classLabel>
<deletedAxiom>&apos;TET1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Oxidation/Reduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113232</classIRI>
<classLabel>MIR31 Pre-miRNA</classLabel>
<newAxiom>&apos;MIR31 Pre-miRNA&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;MIR31 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6430</classIRI>
<classLabel>Thymic Carcinoid Tumor</classLabel>
<deletedAxiom>&apos;Thymic Carcinoid Tumor&apos; EquivalentTo &apos;Foregut Carcinoid Tumor&apos; and &apos;Thymus Epithelial Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Thymus Gland&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Thymic Epithelial Tissue&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Thymic Epithelial Cell&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Cushing Syndrome&apos;)</deletedAxiom>
<newAxiom>&apos;Thymic Carcinoid Tumor&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162460 and &apos;Foregut Carcinoid Tumor&apos; and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Cushing Syndrome&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6384</classIRI>
<classLabel>Paratesticular Lipoma</classLabel>
<deletedAxiom>&apos;Paratesticular Lipoma&apos; EquivalentTo &apos;Lipoma&apos; and &apos;Benign Male Reproductive System Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Paratesticular Lipoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162492 and &apos;Lipoma&apos; and &apos;Benign Soft Tissue Neoplasm&apos; and &apos;Benign Male Reproductive System Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6382</classIRI>
<classLabel>Epididymal Adenomatoid Tumor</classLabel>
<deletedAxiom>&apos;Epididymal Adenomatoid Tumor&apos; EquivalentTo &apos;Benign Epididymal Neoplasm&apos; and &apos;Adenomatoid Tumor&apos;</deletedAxiom>
<newAxiom>&apos;Epididymal Adenomatoid Tumor&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162476 and &apos;Benign Epididymal Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6371</classIRI>
<classLabel>Giant Condyloma Acuminatum</classLabel>
<deletedAxiom>&apos;Giant Condyloma Acuminatum&apos; EquivalentTo &apos;Condyloma Acuminatum&apos; and &apos;Penile Neoplasm&apos; and &apos;Male Reproductive System Precancerous Condition&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Penis&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Slow Growing Mass&apos;)</deletedAxiom>
<newAxiom>&apos;Giant Condyloma Acuminatum&apos; EquivalentTo &apos;Condyloma Acuminatum&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Slow Growing Mass&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Cauliflower-Like Mass&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6360</classIRI>
<classLabel>Testicular Carcinoid Tumor</classLabel>
<deletedAxiom>&apos;Testicular Carcinoid Tumor&apos; EquivalentTo &apos;Carcinoid Tumor&apos; and &apos;Testicular Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Testis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Trabecular Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Organoid Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Rosette Formation&apos;)</deletedAxiom>
<newAxiom>&apos;Testicular Carcinoid Tumor&apos; EquivalentTo &apos;Carcinoid Tumor&apos; and &apos;Monodermal Testicular Teratoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Trabecular Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Organoid Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Rosette Formation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17286</classIRI>
<classLabel>cAMP Responsive Element Binding Protein</classLabel>
<deletedAxiom>&apos;cAMP Responsive Element Binding Protein&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Activation&apos;</deletedAxiom>
<newAxiom>&apos;cAMP Responsive Element Binding Protein&apos; SubClassOf &apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Sequence-Specific DNA Binding Protein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6252</classIRI>
<classLabel>Childhood Brain Anaplastic Astrocytoma</classLabel>
<deletedAxiom>&apos;Childhood Brain Anaplastic Astrocytoma&apos; EquivalentTo &apos;Primary Malignant Brain Neoplasm&apos; and &apos;Brain Astrocytoma&apos; and &apos;Childhood Anaplastic Astrocytoma&apos; and &apos;Childhood Brain Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Childhood Brain Anaplastic Astrocytoma&apos; EquivalentTo &apos;Malignant Brain Neoplasm&apos; and &apos;Brain Astrocytoma&apos; and &apos;Childhood Anaplastic Astrocytoma&apos; and &apos;Childhood Brain Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131574</classIRI>
<classLabel>Temporal Lobe Ependymal Tumor</classLabel>
<deletedAxiom>&apos;Temporal Lobe Ependymal Tumor&apos; EquivalentTo &apos;Supratentorial Ependymal Tumor&apos; and &apos;Primary Cerebral Neoplasm&apos; and &apos;Ependymal Tumor of Brain&apos; and &apos;Temporal Lobe Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Temporal Lobe Ependymal Tumor&apos; EquivalentTo &apos;Supratentorial Ependymal Tumor&apos; and &apos;Ependymal Tumor of Brain&apos; and &apos;Cerebral Neoplasm&apos; and &apos;Temporal Lobe Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Temporal Lobe&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131573</classIRI>
<classLabel>Frontal Lobe Ependymal Tumor</classLabel>
<deletedAxiom>&apos;Frontal Lobe Ependymal Tumor&apos; EquivalentTo &apos;Supratentorial Ependymal Tumor&apos; and &apos;Primary Cerebral Neoplasm&apos; and &apos;Frontal Lobe Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Frontal Lobe Ependymal Tumor&apos; EquivalentTo &apos;Supratentorial Ependymal Tumor&apos; and &apos;Cerebral Neoplasm&apos; and &apos;Frontal Lobe Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Frontal Lobe&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131575</classIRI>
<classLabel>Parietal Lobe Ependymal Tumor</classLabel>
<deletedAxiom>&apos;Parietal Lobe Ependymal Tumor&apos; EquivalentTo &apos;Supratentorial Ependymal Tumor&apos; and &apos;Primary Cerebral Neoplasm&apos; and &apos;Parietal Lobe Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Parietal Lobe Ependymal Tumor&apos; EquivalentTo &apos;Supratentorial Ependymal Tumor&apos; and &apos;Cerebral Neoplasm&apos; and &apos;Parietal Lobe Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Parietal Lobe&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C106232</classIRI>
<classLabel>POLE Gene</classLabel>
<newAxiom>&apos;POLE Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162484</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C106224</classIRI>
<classLabel>POLD1 Gene</classLabel>
<newAxiom>&apos;POLD1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162484</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4642</classIRI>
<classLabel>Brain Glioblastoma</classLabel>
<deletedAxiom>&apos;Brain Glioblastoma&apos; EquivalentTo &apos;Glioblastoma&apos; and &apos;Primary Malignant Brain Neoplasm&apos; and (((&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EGFR Gene Amplification&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EGFR Protein Overexpression&apos;)) or ((&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PDGFRA Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PDGFRalpha Protein Overexpression&apos;))) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;MDM2 Gene Amplification&apos;)</deletedAxiom>
<newAxiom>&apos;Brain Glioblastoma&apos; EquivalentTo &apos;Glioblastoma&apos; and &apos;Malignant Brain Neoplasm&apos; and (((&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EGFR Gene Amplification&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EGFR Protein Overexpression&apos;)) or ((&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PDGFRA Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PDGFRalpha Protein Overexpression&apos;))) and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Brain&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;MDM2 Gene Amplification&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131080</classIRI>
<classLabel>Testicular Failure</classLabel>
<deletedAxiom>&apos;Testicular Failure&apos; SubClassOf &apos;Testicular Disorder&apos;</deletedAxiom>
<newAxiom>&apos;Testicular Failure&apos; SubClassOf &apos;Male Reproductive System Finding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4586</classIRI>
<classLabel>Metastatic Malignant Neoplasm in the Eye</classLabel>
<deletedAxiom>&apos;Metastatic Malignant Neoplasm in the Eye&apos; EquivalentTo &apos;Metastatic Malignant Neoplasm&apos; and &apos;Malignant Eye Neoplasm&apos; and (&apos;Disease_Has_Metastatic_Anatomic_Site&apos; some &apos;Eye&apos;)</deletedAxiom>
<newAxiom>&apos;Metastatic Malignant Neoplasm in the Eye&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162594 and &apos;Malignant Eye Neoplasm&apos; and (&apos;Disease_Has_Metastatic_Anatomic_Site&apos; some &apos;Eye&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159814</classIRI>
<classLabel>Outcome Measure of Success at Form Completion Unknown</classLabel>
<deletedAxiom>&apos;Outcome Measure of Success at Form Completion Unknown&apos; SubClassOf &apos;CPTAC Questions&apos;</deletedAxiom>
<newAxiom>&apos;Outcome Measure of Success at Form Completion Unknown&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C111988</classIRI>
<classLabel>FGFR Inhibitor Debio 1347</classLabel>
<deletedAxiom>&apos;FGFR Inhibitor Debio 1347&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159989</classIRI>
<classLabel>Antithymocyte Globulin Equine Regimen</classLabel>
<deletedAxiom>&apos;Antithymocyte Globulin Equine Regimen&apos; SubClassOf &apos;Chemotherapy_Regimen_Has_Component&apos; some &apos;Horse Anti-thymocyte Globulin&apos;</deletedAxiom>
<newAxiom>&apos;Antithymocyte Globulin Equine Regimen&apos; SubClassOf &apos;Chemotherapy_Regimen_Has_Component&apos; some &apos;Equine Thymocyte Immune Globulin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4970</classIRI>
<classLabel>Cerebral Embryonal Tumor, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Cerebral Embryonal Tumor, Not Otherwise Specified&apos; EquivalentTo &apos;Primary Cerebral Neoplasm&apos; and &apos;Malignant Cerebral Neoplasm&apos; and &apos;Primary Malignant Brain Neoplasm&apos; and &apos;Supratentorial Embryonal Tumor, Not Otherwise Specified&apos;</deletedAxiom>
<newAxiom>&apos;Cerebral Embryonal Tumor, Not Otherwise Specified&apos; EquivalentTo &apos;Malignant Cerebral Neoplasm&apos; and &apos;Cerebral Neoplasm&apos; and &apos;Supratentorial Embryonal Tumor, Not Otherwise Specified&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cerebral Hemisphere&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4951</classIRI>
<classLabel>Cerebral Astrocytoma</classLabel>
<deletedAxiom>&apos;Cerebral Astrocytoma&apos; EquivalentTo &apos;Primary Cerebral Neoplasm&apos; and &apos;Brain Astrocytoma&apos; and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Poorly Differentiated Neoplastic Astrocyte&apos;)</deletedAxiom>
<newAxiom>&apos;Cerebral Astrocytoma&apos; EquivalentTo &apos;Brain Astrocytoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cerebral Hemisphere&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Poorly Differentiated Neoplastic Astrocyte&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4952</classIRI>
<classLabel>Primary Brain Neoplasm</classLabel>
<deletedAxiom>&apos;Primary Brain Neoplasm&apos; EquivalentTo &apos;Brain Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Brain&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Brain Neoplasm&apos; EquivalentTo &apos;Brain Neoplasm&apos; and &apos;Non-Metastatic Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Brain&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4979</classIRI>
<classLabel>Primary Carcinoma Unspecified Site</classLabel>
<deletedAxiom>&apos;Primary Carcinoma Unspecified Site&apos; EquivalentTo &apos;Primary Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Site Unspecified&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Carcinoma Unspecified Site&apos; EquivalentTo &apos;Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Site Unspecified&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4975</classIRI>
<classLabel>Primary Brain Stem Neoplasm</classLabel>
<deletedAxiom>&apos;Primary Brain Stem Neoplasm&apos; EquivalentTo &apos;Brain Stem Neoplasm&apos; and &apos;Primary Brain Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Brain Stem&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Brain Stem Neoplasm&apos; EquivalentTo &apos;Brain Stem Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Brain Stem&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C37249</classIRI>
<classLabel>t(2;22)(q33;q12)</classLabel>
<newAxiom>&apos;t(2;22)(q33;q12)&apos; SubClassOf &apos;Molecular_Abnormality_Involves_Gene&apos; some &apos;CREB1 Gene&apos;</newAxiom>
<newAxiom>&apos;t(2;22)(q33;q12)&apos; SubClassOf &apos;Molecular_Abnormality_Involves_Gene&apos; some &apos;EWSR1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4807</classIRI>
<classLabel>Cerebral Meningioma</classLabel>
<deletedAxiom>&apos;Cerebral Meningioma&apos; EquivalentTo &apos;Primary Cerebral Neoplasm&apos; and &apos;Supratentorial Meningioma&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Cerebral Meninges&apos;)</deletedAxiom>
<newAxiom>&apos;Cerebral Meningioma&apos; EquivalentTo &apos;Cerebral Neoplasm&apos; and &apos;Supratentorial Meningioma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cerebral Hemisphere&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Cerebral Meninges&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4826</classIRI>
<classLabel>Central Nervous System Neuroblastoma</classLabel>
<deletedAxiom>&apos;Central Nervous System Neuroblastoma&apos; EquivalentTo &apos;Primary Cerebral Neoplasm&apos; and &apos;Neuroblastoma&apos; and &apos;Malignant Cerebral Neoplasm&apos; and &apos;Primary Malignant Brain Neoplasm&apos; and &apos;Central Nervous System Embryonal Neoplasm&apos; and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 17q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 1p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 11q ATM Gene Locus&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;MYC Gene Amplification&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NMYC Gene Amplification&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;C-KIT Tyrosine Kinase Protein Overexpression&apos;)</deletedAxiom>
<newAxiom>&apos;Central Nervous System Neuroblastoma&apos; EquivalentTo &apos;Neuroblastoma&apos; and &apos;Malignant Cerebral Neoplasm&apos; and &apos;Cerebral Neoplasm&apos; and &apos;Central Nervous System Embryonal Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cerebral Hemisphere&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 17q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 1p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 11q ATM Gene Locus&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;MYC Gene Amplification&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NMYC Gene Amplification&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;C-KIT Tyrosine Kinase Protein Overexpression&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4733</classIRI>
<classLabel>Peutz-Jeghers Polyp</classLabel>
<deletedAxiom>&apos;Peutz-Jeghers Polyp&apos; EquivalentTo &apos;Gastrointestinal Hamartoma&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;LKB1 Gene Inactivation&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Peutz-Jeghers Syndrome&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;STK11 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Peutz-Jeghers Polyp&apos; SubClassOf &apos;Disease_Has_Associated_Disease&apos; some &apos;Peutz-Jeghers Syndrome&apos;</newAxiom>
<newAxiom>&apos;Peutz-Jeghers Polyp&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;STK11 Gene&apos;</newAxiom>
<newAxiom>&apos;Peutz-Jeghers Polyp&apos; SubClassOf &apos;Gastrointestinal Hamartoma&apos;</newAxiom>
<newAxiom>&apos;Peutz-Jeghers Polyp&apos; SubClassOf &apos;Disease_Has_Molecular_Abnormality&apos; some &apos;STK11 Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159244</classIRI>
<classLabel>Non-Human Papillomavirus-Related Squamous Cell Carcinoma of the Penis</classLabel>
<deletedAxiom>&apos;Non-Human Papillomavirus-Related Squamous Cell Carcinoma of the Penis&apos; EquivalentTo &apos;Squamous Cell Carcinoma of the Penis&apos; and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Non-Human Papillomavirus-Related Squamous Cell Carcinoma of the Penis&apos; EquivalentTo &apos;Squamous Cell Carcinoma of the Penis&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Human Papillomavirus Negative&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159215</classIRI>
<classLabel>Cytogenetic Abnormality Positive by FISH</classLabel>
<deletedAxiom>&apos;Cytogenetic Abnormality Positive by FISH&apos; SubClassOf &apos;Other Finding&apos;</deletedAxiom>
<newAxiom>&apos;Cytogenetic Abnormality Positive by FISH&apos; SubClassOf &apos;Genetic Finding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159229</classIRI>
<classLabel>Cytogenetic Risk Group-CALGB Criteria for AML</classLabel>
<deletedAxiom>&apos;Cytogenetic Risk Group-CALGB Criteria for AML&apos; SubClassOf &apos;Hematopoietic System Finding&apos;</deletedAxiom>
<newAxiom>&apos;Cytogenetic Risk Group-CALGB Criteria for AML&apos; SubClassOf &apos;CPTAC Responses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C37997</classIRI>
<classLabel>Nyctalopia</classLabel>
<deletedAxiom>&apos;Nyctalopia&apos; SubClassOf &apos;Visual Manifestations&apos;</deletedAxiom>
<newAxiom>&apos;Nyctalopia&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C151979</classIRI>
<classLabel>Refractory High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements</classLabel>
<deletedAxiom>&apos;Refractory High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements&apos; EquivalentTo &apos;High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements&apos; and &apos;Refractory Mature B-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements&apos; EquivalentTo &apos;High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements&apos; and &apos;Refractory High-Grade B-Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C151980</classIRI>
<classLabel>Recurrent High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements</classLabel>
<deletedAxiom>&apos;Recurrent High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements&apos; EquivalentTo &apos;High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements&apos; and &apos;Recurrent B-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements&apos; EquivalentTo &apos;High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements&apos; and &apos;Recurrent High-Grade B-Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112205</classIRI>
<classLabel>Pan-FGFR Tyrosine Kinase Inhibitor BAY1163877</classLabel>
<deletedAxiom>&apos;Pan-FGFR Tyrosine Kinase Inhibitor BAY1163877&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82723</classIRI>
<classLabel>MIR29A Pre-miRNA</classLabel>
<newAxiom>&apos;MIR29A Pre-miRNA&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;MIR29A Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18253</classIRI>
<classLabel>STK11 Gene</classLabel>
<newAxiom>&apos;STK11 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162466</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82827</classIRI>
<classLabel>MIR376A1 Pre-miRNA</classLabel>
<newAxiom>&apos;MIR376A1 Pre-miRNA&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;MIR376A1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5123</classIRI>
<classLabel>Hemispheric Anaplastic Astrocytoma</classLabel>
<deletedAxiom>&apos;Hemispheric Anaplastic Astrocytoma&apos; EquivalentTo &apos;Primary Cerebral Neoplasm&apos; and &apos;Malignant Cerebral Neoplasm&apos; and &apos;Cerebral Astrocytoma&apos; and &apos;Primary Malignant Brain Neoplasm&apos; and &apos;Anaplastic Astrocytoma&apos;</deletedAxiom>
<newAxiom>&apos;Hemispheric Anaplastic Astrocytoma&apos; EquivalentTo &apos;Malignant Cerebral Neoplasm&apos; and &apos;Cerebral Neoplasm&apos; and &apos;Cerebral Astrocytoma&apos; and &apos;Anaplastic Astrocytoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cerebral Hemisphere&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5124</classIRI>
<classLabel>Anaplastic Diencephalic Astrocytoma</classLabel>
<deletedAxiom>&apos;Anaplastic Diencephalic Astrocytoma&apos; EquivalentTo &apos;Primary Malignant Brain Neoplasm&apos; and &apos;Malignant Diencephalic Neoplasm&apos; and &apos;Diencephalic Astrocytoma&apos; and &apos;Anaplastic Astrocytoma&apos;</deletedAxiom>
<newAxiom>&apos;Anaplastic Diencephalic Astrocytoma&apos; EquivalentTo &apos;Malignant Diencephalic Neoplasm&apos; and &apos;Diencephalic Astrocytoma&apos; and &apos;Anaplastic Astrocytoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5060</classIRI>
<classLabel>Non-Metastatic Fibrosarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Fibrosarcoma&apos; EquivalentTo &apos;Fibrosarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Fibrosarcoma&apos; EquivalentTo &apos;Fibrosarcoma&apos; and &apos;Non-Metastatic Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5014</classIRI>
<classLabel>Recurrent Lung Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Recurrent Lung Squamous Cell Carcinoma&apos; EquivalentTo &apos;Lung Squamous Cell Carcinoma&apos; and &apos;Recurrent Lung Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Dyspnea&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemoptysis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cough&apos;)</deletedAxiom>
<newAxiom>&apos;Recurrent Lung Squamous Cell Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162652 and &apos;Lung Squamous Cell Carcinoma&apos; and &apos;Recurrent Lung Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Dyspnea&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemoptysis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cough&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C154272</classIRI>
<classLabel>Ipilimumab/Nivolumab Regimen</classLabel>
<newAxiom>&apos;Ipilimumab/Nivolumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Colorectal Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7836</classIRI>
<classLabel>Regional Neuroblastoma</classLabel>
<deletedAxiom>&apos;Regional Neuroblastoma&apos; EquivalentTo &apos;Neuroblastoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Regional Disease&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 17q&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NMYC Gene Amplification&apos;)</deletedAxiom>
<newAxiom>&apos;Regional Neuroblastoma&apos; EquivalentTo &apos;Neuroblastoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Regional Disease&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 17q&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NMYC Gene Amplification&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7862</classIRI>
<classLabel>Regional Digestive System Neuroendocrine Tumor G1</classLabel>
<deletedAxiom>&apos;Regional Digestive System Neuroendocrine Tumor G1&apos; EquivalentTo &apos;Digestive System Neuroendocrine Tumor G1&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Regional Disease&apos;)</deletedAxiom>
<newAxiom>&apos;Regional Digestive System Neuroendocrine Tumor G1&apos; EquivalentTo &apos;Digestive System Neuroendocrine Tumor G1&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Regional Disease&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120102</classIRI>
<classLabel>FGFR4 Inhibitor FGF401</classLabel>
<deletedAxiom>&apos;FGFR4 Inhibitor FGF401&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120257</classIRI>
<classLabel>California Verbal Learning Test - Second Edition</classLabel>
<deletedAxiom>&apos;California Verbal Learning Test - Second Edition&apos; SubClassOf &apos;Clinical or Research Assessment Questionnaire&apos;</deletedAxiom>
<newAxiom>&apos;California Verbal Learning Test - Second Edition&apos; SubClassOf &apos;Research or Clinical Assessment Tool&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C149606</classIRI>
<classLabel>Intramammary Ointment Dosage Form</classLabel>
<newAxiom>&apos;Intramammary Ointment Dosage Form&apos; SubClassOf &apos;Ointment Dosage Form&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101666</classIRI>
<classLabel>MIR375 Pre-miRNA</classLabel>
<deletedAxiom>&apos;MIR375 Pre-miRNA&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;RNA Interference&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83080</classIRI>
<classLabel>Physical Examination Sponsor Defined Identifier</classLabel>
<deletedAxiom>&apos;Physical Examination Sponsor Defined Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Physical Examination Sponsor Defined Identifier&apos; SubClassOf &apos;Sponsor ID&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83084</classIRI>
<classLabel>Vital Signs Sponsor Defined Identifier</classLabel>
<deletedAxiom>&apos;Vital Signs Sponsor Defined Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Vital Signs Sponsor Defined Identifier&apos; SubClassOf &apos;Sponsor ID&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83077</classIRI>
<classLabel>Protocol Deviation Sponsor Defined Identifier</classLabel>
<deletedAxiom>&apos;Protocol Deviation Sponsor Defined Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Protocol Deviation Sponsor Defined Identifier&apos; SubClassOf &apos;Sponsor ID&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83074</classIRI>
<classLabel>Adverse Event Sponsor Defined Identifier</classLabel>
<deletedAxiom>&apos;Adverse Event Sponsor Defined Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Adverse Event Sponsor Defined Identifier&apos; SubClassOf &apos;Sponsor ID&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83075</classIRI>
<classLabel>Concomitant Medication Use Sponsor Defined Identifier</classLabel>
<deletedAxiom>&apos;Concomitant Medication Use Sponsor Defined Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Concomitant Medication Use Sponsor Defined Identifier&apos; SubClassOf &apos;Sponsor ID&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83079</classIRI>
<classLabel>Medical History Sponsor Defined Identifier</classLabel>
<deletedAxiom>&apos;Medical History Sponsor Defined Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Medical History Sponsor Defined Identifier&apos; SubClassOf &apos;Sponsor ID&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83250</classIRI>
<classLabel>Disposition Sponsor Defined Identifier</classLabel>
<deletedAxiom>&apos;Disposition Sponsor Defined Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Disposition Sponsor Defined Identifier&apos; SubClassOf &apos;Sponsor ID&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83287</classIRI>
<classLabel>Exposure Sponsor Defined Identifier</classLabel>
<deletedAxiom>&apos;Exposure Sponsor Defined Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Exposure Sponsor Defined Identifier&apos; SubClassOf &apos;Sponsor ID&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83316</classIRI>
<classLabel>Laboratory Test Sponsor Defined Identifier</classLabel>
<deletedAxiom>&apos;Laboratory Test Sponsor Defined Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Laboratory Test Sponsor Defined Identifier&apos; SubClassOf &apos;Sponsor ID&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83300</classIRI>
<classLabel>Inclusion Exclusion Criterion Sponsor Defined Identifier</classLabel>
<deletedAxiom>&apos;Inclusion Exclusion Criterion Sponsor Defined Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Inclusion Exclusion Criterion Sponsor Defined Identifier&apos; SubClassOf &apos;Sponsor ID&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83380</classIRI>
<classLabel>Questionnaire Sponsor Defined Identifier</classLabel>
<deletedAxiom>&apos;Questionnaire Sponsor Defined Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Questionnaire Sponsor Defined Identifier&apos; SubClassOf &apos;Sponsor ID&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83404</classIRI>
<classLabel>Subject Characteristics Sponsor Defined Identifier</classLabel>
<deletedAxiom>&apos;Subject Characteristics Sponsor Defined Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Subject Characteristics Sponsor Defined Identifier&apos; SubClassOf &apos;Sponsor ID&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83429</classIRI>
<classLabel>Substance Use Sponsor Defined Identifier</classLabel>
<deletedAxiom>&apos;Substance Use Sponsor Defined Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Substance Use Sponsor Defined Identifier&apos; SubClassOf &apos;Sponsor ID&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8167</classIRI>
<classLabel>Localized Urothelial Carcinoma of the Renal Pelvis and Ureter</classLabel>
<deletedAxiom>&apos;Localized Urothelial Carcinoma of the Renal Pelvis and Ureter&apos; EquivalentTo &apos;Localized Carcinoma&apos; and &apos;Renal Pelvis and Ureter Urothelial Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Flank Pain&apos;)</deletedAxiom>
<newAxiom>&apos;Localized Urothelial Carcinoma of the Renal Pelvis and Ureter&apos; EquivalentTo &apos;Localized Carcinoma&apos; and &apos;Regional Urothelial Carcinoma of the Renal Pelvis and Ureter&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Flank Pain&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8168</classIRI>
<classLabel>Regional Urothelial Carcinoma of the Renal Pelvis and Ureter</classLabel>
<deletedAxiom>&apos;Regional Urothelial Carcinoma of the Renal Pelvis and Ureter&apos; EquivalentTo &apos;Renal Pelvis and Ureter Urothelial Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Regional Disease&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Flank Pain&apos;)</deletedAxiom>
<newAxiom>&apos;Regional Urothelial Carcinoma of the Renal Pelvis and Ureter&apos; EquivalentTo &apos;Renal Pelvis and Ureter Urothelial Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Regional Disease&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Flank Pain&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101244</classIRI>
<classLabel>Tobacco Cessation Counseling</classLabel>
<newAxiom>&apos;Tobacco Cessation Counseling&apos; SubClassOf &apos;Smoking Cessation Intervention&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8045</classIRI>
<classLabel>Regional Adrenal Gland Pheochromocytoma</classLabel>
<deletedAxiom>&apos;Regional Adrenal Gland Pheochromocytoma&apos; EquivalentTo &apos;Adrenal Gland Pheochromocytoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Regional Disease&apos;)</deletedAxiom>
<newAxiom>&apos;Regional Adrenal Gland Pheochromocytoma&apos; EquivalentTo &apos;Adrenal Gland Pheochromocytoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Regional Disease&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8067</classIRI>
<classLabel>Recurrent Childhood Soft Tissue Sarcoma</classLabel>
<deletedAxiom>&apos;Recurrent Childhood Soft Tissue Sarcoma&apos; EquivalentTo &apos;Recurrent Primary Malignant Neoplasm&apos; and &apos;Recurrent Soft Tissue Sarcoma&apos; and &apos;Primary Childhood Soft Tissue Sarcoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Childhood Soft Tissue Sarcoma&apos; EquivalentTo &apos;Recurrent Soft Tissue Sarcoma&apos; and &apos;Childhood Soft Tissue Sarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8065</classIRI>
<classLabel>Primary Childhood Soft Tissue Sarcoma</classLabel>
<deletedAxiom>&apos;Primary Childhood Soft Tissue Sarcoma&apos; EquivalentTo &apos;Childhood Soft Tissue Sarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Childhood Soft Tissue Sarcoma&apos; EquivalentTo &apos;Non-Metastatic Childhood Soft Tissue Sarcoma&apos; and &apos;Childhood Rhabdomyosarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8633</classIRI>
<classLabel>Recurrent Esophageal Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Recurrent Esophageal Squamous Cell Carcinoma&apos; EquivalentTo &apos;Recurrent Esophageal Carcinoma&apos; and &apos;Esophageal Squamous Cell Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Esophageal Squamous Cell Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162652 and &apos;Recurrent Esophageal Carcinoma&apos; and &apos;Esophageal Squamous Cell Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8528</classIRI>
<classLabel>Metastatic Malignant Neoplasm in the Neck</classLabel>
<deletedAxiom>&apos;Metastatic Malignant Neoplasm in the Neck&apos; EquivalentTo &apos;Metastatic Malignant Neoplasm&apos; and &apos;Malignant Neck Neoplasm&apos; and (&apos;Disease_Has_Metastatic_Anatomic_Site&apos; some &apos;Neck&apos;)</deletedAxiom>
<newAxiom>&apos;Metastatic Malignant Neoplasm in the Neck&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162594 and &apos;Malignant Neck Neoplasm&apos; and (&apos;Disease_Has_Metastatic_Anatomic_Site&apos; some &apos;Neck&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8548</classIRI>
<classLabel>Benign Cerebral Neoplasm</classLabel>
<deletedAxiom>&apos;Benign Cerebral Neoplasm&apos; EquivalentTo &apos;Primary Cerebral Neoplasm&apos; and &apos;Benign Supratentorial Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Benign Cerebral Neoplasm&apos; EquivalentTo &apos;Benign Supratentorial Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cerebral Hemisphere&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8556</classIRI>
<classLabel>Metastatic Malignant Neoplasm in the Orbit</classLabel>
<deletedAxiom>&apos;Metastatic Malignant Neoplasm in the Orbit&apos; EquivalentTo &apos;Malignant Orbit Neoplasm&apos; and &apos;Metastatic Malignant Neoplasm&apos; and (&apos;Disease_Has_Metastatic_Anatomic_Site&apos; some &apos;Orbit&apos;)</deletedAxiom>
<newAxiom>&apos;Metastatic Malignant Neoplasm in the Orbit&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162594 and &apos;Malignant Orbit Neoplasm&apos; and (&apos;Disease_Has_Metastatic_Anatomic_Site&apos; some &apos;Orbit&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8542</classIRI>
<classLabel>Metastatic Malignant Neoplasm in the Lip</classLabel>
<deletedAxiom>&apos;Metastatic Malignant Neoplasm in the Lip&apos; EquivalentTo &apos;Metastatic Malignant Neoplasm&apos; and &apos;Malignant Lip Neoplasm&apos; and (&apos;Disease_Has_Metastatic_Anatomic_Site&apos; some &apos;Lip&apos;)</deletedAxiom>
<newAxiom>&apos;Metastatic Malignant Neoplasm in the Lip&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162594 and &apos;Malignant Lip Neoplasm&apos; and (&apos;Disease_Has_Metastatic_Anatomic_Site&apos; some &apos;Lip&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8374</classIRI>
<classLabel>Bowenoid Papulosis</classLabel>
<deletedAxiom>&apos;Bowenoid Papulosis&apos; EquivalentTo &apos;Pre-Malignant Skin Epithelial Lesion&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Multifocal Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Severe Dysplasia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Papular Lesion&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Human Papillomavirus Infection&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;TP53 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Bowenoid Papulosis&apos; EquivalentTo &apos;Pre-Malignant Skin Epithelial Lesion&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Multifocal Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Papular Lesion&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Human Papillomavirus Infection&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;TP53 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129820</classIRI>
<classLabel>Antineoplastic Immunomodulating Agent</classLabel>
<newAxiom>&apos;Antineoplastic Immunomodulating Agent&apos; SubClassOf &apos;Antineoplastic Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129821</classIRI>
<classLabel>Antineoplastic Biological Agent</classLabel>
<newAxiom>&apos;Antineoplastic Biological Agent&apos; SubClassOf &apos;Antineoplastic Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115292</classIRI>
<classLabel>Non-Metastatic Childhood Soft Tissue Sarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Childhood Soft Tissue Sarcoma&apos; EquivalentTo &apos;Childhood Soft Tissue Sarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;No Evidence of Metastatic Disease&apos;)</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Childhood Soft Tissue Sarcoma&apos; EquivalentTo &apos;Non-Metastatic Neoplasm&apos; and &apos;Childhood Soft Tissue Sarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8943</classIRI>
<classLabel>Metastatic Endometrioid Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Metastatic Endometrioid Adenocarcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and &apos;Endometrioid Adenocarcinoma&apos; and &apos;Metastatic Adenocarcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Endometrioid Adenocarcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162254 and &apos;Endometrioid Adenocarcinoma&apos; and &apos;Metastatic Adenocarcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8902</classIRI>
<classLabel>Recurrent Bladder Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Recurrent Bladder Squamous Cell Carcinoma&apos; EquivalentTo &apos;Bladder Squamous Cell Carcinoma&apos; and &apos;Recurrent Bladder Carcinoma&apos; and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 1q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 13q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 3p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 9p&apos;)</deletedAxiom>
<newAxiom>&apos;Recurrent Bladder Squamous Cell Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162652 and &apos;Bladder Squamous Cell Carcinoma&apos; and &apos;Recurrent Bladder Carcinoma&apos; and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 1q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 13q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 3p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 9p&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8809</classIRI>
<classLabel>Non-Metastatic Extraskeletal Osteosarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Extraskeletal Osteosarcoma&apos; EquivalentTo &apos;Extraskeletal Osteosarcoma&apos; and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Extraskeletal Osteosarcoma&apos; EquivalentTo &apos;Non-Metastatic Neoplasm&apos; and &apos;Extraskeletal Osteosarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8802</classIRI>
<classLabel>Non-Metastatic Extraskeletal Ewing Sarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Extraskeletal Ewing Sarcoma&apos; EquivalentTo &apos;Extraskeletal Ewing Sarcoma&apos; and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Extraskeletal Ewing Sarcoma&apos; EquivalentTo &apos;Non-Metastatic Neoplasm&apos; and &apos;Extraskeletal Ewing Sarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8800</classIRI>
<classLabel>Primary Epithelioid Sarcoma</classLabel>
<deletedAxiom>&apos;Primary Epithelioid Sarcoma&apos; EquivalentTo &apos;Epithelioid Sarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Epithelioid Sarcoma&apos; EquivalentTo &apos;Non-Metastatic Neoplasm&apos; and &apos;Epithelioid Sarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8826</classIRI>
<classLabel>Primary Synovial Sarcoma</classLabel>
<deletedAxiom>&apos;Primary Synovial Sarcoma&apos; EquivalentTo &apos;Synovial Sarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Synovial Sarcoma&apos; EquivalentTo &apos;Synovial Sarcoma&apos; and &apos;Non-Metastatic Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8817</classIRI>
<classLabel>Primary Liposarcoma</classLabel>
<deletedAxiom>&apos;Primary Liposarcoma&apos; EquivalentTo &apos;Liposarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Liposarcoma&apos; EquivalentTo &apos;Liposarcoma&apos; and &apos;Non-Metastatic Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8814</classIRI>
<classLabel>Primary Leiomyosarcoma</classLabel>
<deletedAxiom>&apos;Primary Leiomyosarcoma&apos; EquivalentTo &apos;Leiomyosarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Leiomyosarcoma&apos; EquivalentTo &apos;Leiomyosarcoma&apos; and &apos;Non-Metastatic Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8797</classIRI>
<classLabel>Primary Alveolar Soft Part Sarcoma</classLabel>
<deletedAxiom>&apos;Primary Alveolar Soft Part Sarcoma&apos; EquivalentTo &apos;Alveolar Soft Part Sarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Alveolar Soft Part Sarcoma&apos; EquivalentTo &apos;Non-Metastatic Neoplasm&apos; and &apos;Alveolar Soft Part Sarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8716</classIRI>
<classLabel>Regional Malignant Ureter Neoplasm</classLabel>
<deletedAxiom>&apos;Regional Malignant Ureter Neoplasm&apos; EquivalentTo &apos;Malignant Ureter Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Ureter&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Regional Disease&apos;)</deletedAxiom>
<newAxiom>&apos;Regional Malignant Ureter Neoplasm&apos; EquivalentTo &apos;Malignant Ureter Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Ureter&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Regional Disease&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129427</classIRI>
<classLabel>Multinodular and Vacuolated Tumor of the Cerebrum</classLabel>
<deletedAxiom>&apos;Multinodular and Vacuolated Tumor of the Cerebrum&apos; EquivalentTo &apos;Primary Brain Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cerebral Hemisphere&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Multinodular and Vacuolated Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Low Grade Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Glial Differentiation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Neuronal Differentiation&apos;)</deletedAxiom>
<newAxiom>&apos;Multinodular and Vacuolated Tumor of the Cerebrum&apos; EquivalentTo &apos;Cerebral Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cerebral Hemisphere&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Multinodular and Vacuolated Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Low Grade Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Glial Differentiation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Neuronal Differentiation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133839</classIRI>
<classLabel>Metastatic Digestive System Carcinoma</classLabel>
<deletedAxiom>&apos;Metastatic Digestive System Carcinoma&apos; EquivalentTo &apos;Metastatic Carcinoma&apos; and &apos;Digestive System Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Digestive System Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162255 and &apos;Metastatic Carcinoma&apos; and &apos;Digestive System Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6460</classIRI>
<classLabel>Thymic Small Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Thymic Small Cell Carcinoma&apos; EquivalentTo &apos;Extrapulmonary Small Cell Carcinoma&apos; and &apos;Thymic Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Thymic Small Cell Carcinoma&apos; EquivalentTo &apos;Extrapulmonary Small Cell Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162460 and &apos;Thymic Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6461</classIRI>
<classLabel>Thymic Large Cell Neuroendocrine Carcinoma</classLabel>
<deletedAxiom>&apos;Thymic Large Cell Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Large Cell Neuroendocrine Carcinoma&apos; and &apos;Thymic Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Thymic Large Cell Neuroendocrine Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162460 and &apos;Large Cell Neuroendocrine Carcinoma&apos; and &apos;Thymic Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133709</classIRI>
<classLabel>Recurrent Head and Neck Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Recurrent Head and Neck Squamous Cell Carcinoma&apos; EquivalentTo &apos;Head and Neck Squamous Cell Carcinoma&apos; and &apos;Recurrent Head and Neck Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Head and Neck Squamous Cell Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162652 and &apos;Head and Neck Squamous Cell Carcinoma&apos; and &apos;Recurrent Head and Neck Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39788</classIRI>
<classLabel>MET Gene Mutation</classLabel>
<newAxiom>&apos;MET Gene Mutation&apos; SubClassOf &apos;Gene_Mutant_Encodes_Gene_Product_Sequence_Variation&apos; some &apos;MET Protein Variant&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C147924</classIRI>
<classLabel>Advanced Lung Non-Squamous Non-Small Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Advanced Lung Non-Squamous Non-Small Cell Carcinoma&apos; EquivalentTo &apos;Metastatic Lung Non-Squamous Non-Small Cell Carcinoma&apos; and &apos;Advanced Lung Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Lung Non-Squamous Non-Small Cell Carcinoma&apos; EquivalentTo &apos;Metastatic Lung Non-Squamous Non-Small Cell Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162158</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39921</classIRI>
<classLabel>Testicular Spermatocytic Seminoma</classLabel>
<deletedAxiom>&apos;Testicular Spermatocytic Seminoma&apos; EquivalentTo &apos;Testicular Seminoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Giant Germ Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Small Germ Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Round Germ Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Edematous Stroma Formation&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;i(12p)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 12p&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Painless Testicular Mass&apos;)</deletedAxiom>
<newAxiom>&apos;Testicular Spermatocytic Seminoma&apos; EquivalentTo &apos;Malignant Testicular Germ Cell Tumor&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Giant Germ Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Small Germ Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Round Germ Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Edematous Stroma Formation&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 9&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 22&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 1&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 20&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Painless Testicular Mass&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;FGFR3 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;HRAS Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39955</classIRI>
<classLabel>Rete Testis Neoplasm</classLabel>
<deletedAxiom>&apos;Rete Testis Neoplasm&apos; EquivalentTo &apos;Male Reproductive System Neoplasm&apos; and (&apos;Disease_Has_Associated_Anatomic_Site&apos; some &apos;Rete Testis&apos;)</deletedAxiom>
<newAxiom>&apos;Rete Testis Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162485 and (&apos;Disease_Has_Associated_Anatomic_Site&apos; some &apos;Rete Testis&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39958</classIRI>
<classLabel>Epididymal Neoplasm</classLabel>
<deletedAxiom>&apos;Epididymal Neoplasm&apos; EquivalentTo &apos;Male Reproductive System Neoplasm&apos; and (&apos;Disease_Has_Associated_Anatomic_Site&apos; some &apos;Epididymis&apos;)</deletedAxiom>
<newAxiom>&apos;Epididymal Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162485 and (&apos;Disease_Has_Associated_Anatomic_Site&apos; some &apos;Epididymis&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39944</classIRI>
<classLabel>Testicular Large Cell Calcifying Sertoli Cell Tumor</classLabel>
<deletedAxiom>&apos;Testicular Large Cell Calcifying Sertoli Cell Tumor&apos; EquivalentTo &apos;Benign Testicular Sertoli Cell Tumor&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Large Polygonal Sertoli Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Calcification&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Gynecomastia&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Carney Complex&apos;)</deletedAxiom>
<newAxiom>&apos;Testicular Large Cell Calcifying Sertoli Cell Tumor&apos; EquivalentTo &apos;Testicular Sertoli Cell Tumor&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Large Polygonal Sertoli Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Calcification&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Gynecomastia&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Carney Complex&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39963</classIRI>
<classLabel>Penile Bowenoid Papulosis</classLabel>
<deletedAxiom>&apos;Penile Bowenoid Papulosis&apos; EquivalentTo &apos;Penile Neoplasm&apos; and &apos;Male Reproductive System Precancerous Condition&apos; and &apos;Bowenoid Papulosis&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Penis&apos;)</deletedAxiom>
<newAxiom>&apos;Penile Bowenoid Papulosis&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162541 and &apos;Bowenoid Papulosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39908</classIRI>
<classLabel>Seminal Vesicle Neoplasm</classLabel>
<deletedAxiom>&apos;Seminal Vesicle Neoplasm&apos; EquivalentTo &apos;Male Reproductive System Neoplasm&apos; and (&apos;Disease_Has_Associated_Anatomic_Site&apos; some &apos;Seminal Vesicle&apos;)</deletedAxiom>
<newAxiom>&apos;Seminal Vesicle Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162485 and (&apos;Disease_Has_Associated_Anatomic_Site&apos; some &apos;Seminal Vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25968</classIRI>
<classLabel>Pre-miRNA</classLabel>
<newAxiom>&apos;Pre-miRNA&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Gene Expression Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25966</classIRI>
<classLabel>MicroRNA</classLabel>
<newAxiom>&apos;MicroRNA&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Gene Expression Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C114774</classIRI>
<classLabel>Childhood Supratentorial Embryonal Tumor, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Childhood Supratentorial Embryonal Tumor, Not Otherwise Specified&apos; EquivalentTo &apos;Primary Malignant Brain Neoplasm&apos; and &apos;Childhood Supratentorial Neoplasm&apos; and &apos;Childhood Central Nervous System Embryonal Tumor, Not Otherwise Specified&apos; and &apos;Supratentorial Embryonal Tumor, Not Otherwise Specified&apos;</deletedAxiom>
<newAxiom>&apos;Childhood Supratentorial Embryonal Tumor, Not Otherwise Specified&apos; EquivalentTo &apos;Malignant Brain Neoplasm&apos; and &apos;Childhood Supratentorial Neoplasm&apos; and &apos;Childhood Central Nervous System Embryonal Tumor, Not Otherwise Specified&apos; and &apos;Supratentorial Embryonal Tumor, Not Otherwise Specified&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45381</classIRI>
<classLabel>CD15-Positive Neoplastic Cells Present</classLabel>
<newAxiom>&apos;CD15-Positive Neoplastic Cells Present&apos; SubClassOf &apos;CD15 Positive&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128862</classIRI>
<classLabel>FGFR4 Inhibitor H3B-6527</classLabel>
<deletedAxiom>&apos;FGFR4 Inhibitor H3B-6527&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C114283</classIRI>
<classLabel>FGFR Inhibitor TAS-120</classLabel>
<deletedAxiom>&apos;FGFR Inhibitor TAS-120&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7713</classIRI>
<classLabel>Squamous Cell Carcinoma Metastatic in the Neck with Occult Primary</classLabel>
<deletedAxiom>&apos;Squamous Cell Carcinoma Metastatic in the Neck with Occult Primary&apos; EquivalentTo &apos;Squamous Cell Carcinoma of Unknown Primary&apos; and &apos;Metastatic Malignant Neoplasm in the Neck&apos;</deletedAxiom>
<newAxiom>&apos;Squamous Cell Carcinoma Metastatic in the Neck with Occult Primary&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162595 and &apos;Squamous Cell Carcinoma of Unknown Primary&apos; and &apos;Metastatic Malignant Neoplasm in the Neck&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7711</classIRI>
<classLabel>Adult Liver Carcinoma</classLabel>
<deletedAxiom>&apos;Adult Liver Carcinoma&apos; EquivalentTo &apos;Liver and Intrahepatic Bile Duct Carcinoma&apos; and &apos;Primary Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Adulthood Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Adult Liver Carcinoma&apos; EquivalentTo &apos;Carcinoma&apos; and &apos;Liver and Intrahepatic Bile Duct Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Adulthood Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7705</classIRI>
<classLabel>Childhood Rhabdomyosarcoma</classLabel>
<deletedAxiom>&apos;Childhood Rhabdomyosarcoma&apos; EquivalentTo &apos;Rhabdomyosarcoma&apos; and &apos;Primary Childhood Soft Tissue Sarcoma&apos; and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;FGFR4 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Childhood Rhabdomyosarcoma&apos; EquivalentTo &apos;Rhabdomyosarcoma&apos; and &apos;Childhood Soft Tissue Sarcoma&apos; and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;FGFR4 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153201</classIRI>
<classLabel>Advanced Lung Non-Small Cell Squamous Carcinoma</classLabel>
<deletedAxiom>&apos;Advanced Lung Non-Small Cell Squamous Carcinoma&apos; EquivalentTo &apos;Advanced Lung Carcinoma&apos; and &apos;Metastatic Lung Non-Small Cell Squamous Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Lung Non-Small Cell Squamous Carcinoma&apos; EquivalentTo &apos;Metastatic Lung Non-Small Cell Squamous Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162158 and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162653</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7730</classIRI>
<classLabel>Penile Sarcoma</classLabel>
<deletedAxiom>&apos;Penile Sarcoma&apos; EquivalentTo &apos;Malignant Penile Neoplasm&apos; and &apos;Soft Tissue Sarcoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Penis&apos;)</deletedAxiom>
<newAxiom>&apos;Penile Sarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162574 and &apos;Malignant Penile Neoplasm&apos; and &apos;Soft Tissue Sarcoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Penis&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7639</classIRI>
<classLabel>Regional Malignant Urethral Neoplasm</classLabel>
<deletedAxiom>&apos;Regional Malignant Urethral Neoplasm&apos; EquivalentTo &apos;Malignant Urethral Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Urethra&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Regional Disease&apos;)</deletedAxiom>
<newAxiom>&apos;Regional Malignant Urethral Neoplasm&apos; EquivalentTo &apos;Malignant Urethral Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Urethra&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Regional Disease&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153387</classIRI>
<classLabel>Metastatic Cervical Carcinoma</classLabel>
<deletedAxiom>&apos;Metastatic Cervical Carcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and &apos;Cervical Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Cervical Carcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162254 and &apos;Cervical Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153311</classIRI>
<classLabel>Horse Anti-thymocyte Globulin</classLabel>
<deletedAxiom>&apos;Horse Anti-thymocyte Globulin&apos; SubClassOf &apos;Anti-Thymocyte Globulin&apos;</deletedAxiom>
<newAxiom>&apos;Horse Anti-thymocyte Globulin&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7611</classIRI>
<classLabel>Cerebral Lymphoma</classLabel>
<deletedAxiom>&apos;Cerebral Lymphoma&apos; EquivalentTo &apos;Primary Cerebral Neoplasm&apos; and &apos;Malignant Cerebral Neoplasm&apos; and &apos;Primary Malignant Brain Neoplasm&apos; and &apos;Central Nervous System Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Cerebral Lymphoma&apos; EquivalentTo &apos;Malignant Cerebral Neoplasm&apos; and &apos;Cerebral Neoplasm&apos; and &apos;Central Nervous System Lymphoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cerebral Hemisphere&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7446</classIRI>
<classLabel>Anaplastic Brain Stem Glioma</classLabel>
<deletedAxiom>&apos;Anaplastic Brain Stem Glioma&apos; EquivalentTo &apos;WHO Grade III Glioma&apos; and &apos;Malignant Brain Stem Neoplasm&apos; and &apos;Anaplastic Malignant Neoplasm&apos; and &apos;Primary Malignant Brain Neoplasm&apos; and &apos;Brain Stem Glioma&apos;</deletedAxiom>
<newAxiom>&apos;Anaplastic Brain Stem Glioma&apos; EquivalentTo &apos;WHO Grade III Glioma&apos; and &apos;Malignant Brain Neoplasm&apos; and &apos;Malignant Brain Stem Neoplasm&apos; and &apos;Anaplastic Malignant Neoplasm&apos; and &apos;Brain Stem Glioma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153136</classIRI>
<classLabel>Rabbit Anti-Thymocyte Globulin</classLabel>
<deletedAxiom>&apos;Rabbit Anti-Thymocyte Globulin&apos; SubClassOf &apos;Anti-Thymocyte Globulin&apos;</deletedAxiom>
<newAxiom>&apos;Rabbit Anti-Thymocyte Globulin&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153184</classIRI>
<classLabel>Advanced Synovial Sarcoma</classLabel>
<deletedAxiom>&apos;Advanced Synovial Sarcoma&apos; EquivalentTo &apos;Advanced Sarcoma&apos; and &apos;Metastatic Synovial Sarcoma&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Synovial Sarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162194 and &apos;Metastatic Synovial Sarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7335</classIRI>
<classLabel>Reproductive Endocrine Neoplasm</classLabel>
<deletedAxiom>&apos;Reproductive Endocrine Neoplasm&apos; EquivalentTo &apos;Gonadal Disorder&apos; and &apos;Endocrine Neoplasm&apos; and &apos;Reproductive System Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Reproductive System&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Cell&apos;)</deletedAxiom>
<newAxiom>&apos;Reproductive Endocrine Neoplasm&apos; EquivalentTo &apos;Gonadal Disorder&apos; and &apos;Endocrine Neoplasm&apos; and &apos;Reproductive System Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Reproductive System&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Neuroendocrine Differentiation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156759</classIRI>
<classLabel>PRMT1 Inhibitor GSK3368715</classLabel>
<deletedAxiom>&apos;PRMT1 Inhibitor GSK3368715&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142195</classIRI>
<classLabel>ATP-Binding Cassette Sub-Family D Member 1</classLabel>
<deletedAxiom>&apos;ATP-Binding Cassette Sub-Family D Member 1&apos; EquivalentTo &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Peroxisome Biogenesis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Peroxisome&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intracellular Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transmembrane Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Lipid Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Fatty Acid Metabolism&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ABCD1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;ATP-Binding Cassette Sub-Family D Member 1&apos; EquivalentTo &apos;Translocase&apos; and &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Peroxisome Biogenesis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Peroxisome&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intracellular Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transmembrane Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Lipid Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Fatty Acid Metabolism&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ABCD1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142193</classIRI>
<classLabel>ABCD1 Gene</classLabel>
<newAxiom>&apos;ABCD1 Gene&apos; SubClassOf &apos;Translocase Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156492</classIRI>
<classLabel>Metastatic Digestive System Neuroendocrine Neoplasm</classLabel>
<deletedAxiom>&apos;Metastatic Digestive System Neuroendocrine Neoplasm&apos; EquivalentTo &apos;Metastatic Neuroendocrine Neoplasm&apos; and &apos;Digestive System Neuroendocrine Neoplasm&apos; and &apos;Malignant Digestive System Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Digestive System Neuroendocrine Neoplasm&apos; EquivalentTo &apos;Metastatic Neuroendocrine Neoplasm&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162255 and &apos;Digestive System Neuroendocrine Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156476</classIRI>
<classLabel>Advanced Kaposi Sarcoma</classLabel>
<deletedAxiom>&apos;Advanced Kaposi Sarcoma&apos; EquivalentTo &apos;Advanced Sarcoma&apos; and &apos;Metastatic Kaposi Sarcoma&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Kaposi Sarcoma&apos; EquivalentTo &apos;Metastatic Kaposi Sarcoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162194</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156463</classIRI>
<classLabel>Loss of Immunohistochemical Expression of Succinate Dehydrogenase (SDH) B</classLabel>
<newAxiom>&apos;Loss of Immunohistochemical Expression of Succinate Dehydrogenase (SDH) B&apos; SubClassOf &apos;SDHB Negative&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122719</classIRI>
<classLabel>FGFR Inhibitor ASP5878</classLabel>
<deletedAxiom>&apos;FGFR Inhibitor ASP5878&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156068</classIRI>
<classLabel>Metastatic Endometrial Carcinoma</classLabel>
<deletedAxiom>&apos;Metastatic Endometrial Carcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and &apos;Endometrial Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Endometrial Carcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162254 and &apos;Endometrial Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156066</classIRI>
<classLabel>Metastatic Vulvar Carcinoma</classLabel>
<deletedAxiom>&apos;Metastatic Vulvar Carcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and &apos;Vulvar Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Vulvar Carcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162254 and &apos;Vulvar Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156065</classIRI>
<classLabel>Metastatic Vaginal Carcinoma</classLabel>
<deletedAxiom>&apos;Metastatic Vaginal Carcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and &apos;Vaginal Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Vaginal Carcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162254 and &apos;Vaginal Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156064</classIRI>
<classLabel>Metastatic Ovarian Carcinoma</classLabel>
<deletedAxiom>&apos;Metastatic Ovarian Carcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and &apos;Ovarian Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Ovarian Carcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162254 and &apos;Ovarian Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156063</classIRI>
<classLabel>Metastatic Fallopian Tube Carcinoma</classLabel>
<deletedAxiom>&apos;Metastatic Fallopian Tube Carcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and &apos;Fallopian Tube Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Fallopian Tube Carcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162254 and &apos;Fallopian Tube Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156006</classIRI>
<classLabel>Absolute Neutrophil Count Greater than or Equal to 500/mm3</classLabel>
<newAxiom>&apos;Absolute Neutrophil Count Greater than or Equal to 500/mm3&apos; SubClassOf &apos;Hematopoietic System Finding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12075</classIRI>
<classLabel>Bevacizumab/Interferon Alfa</classLabel>
<deletedAxiom>&apos;Bevacizumab/Interferon Alfa&apos; SubClassOf &apos;Agent Combination Indexed in Open Clinical Trials&apos;</deletedAxiom>
<newAxiom>&apos;Bevacizumab/Interferon Alfa&apos; SubClassOf &apos;Regimen Used to Treat Malignant Renal Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C161639</classIRI>
<classLabel>Seminal Vesicle Schwannoma</classLabel>
<deletedAxiom>&apos;Seminal Vesicle Schwannoma&apos; EquivalentTo &apos;Seminal Vesicle Soft Tissue Neoplasm&apos; and &apos;Benign Seminal Vesicle Neoplasm&apos; and &apos;Peripheral Nerve Schwannoma&apos;</deletedAxiom>
<newAxiom>&apos;Seminal Vesicle Schwannoma&apos; EquivalentTo &apos;Seminal Vesicle Soft Tissue Neoplasm&apos; and &apos;Benign Seminal Vesicle Neoplasm&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162502</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C161634</classIRI>
<classLabel>Seminal Vesicle Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Seminal Vesicle Squamous Cell Carcinoma&apos; EquivalentTo &apos;Malignant Seminal Vesicle Neoplasm&apos; and &apos;Squamous Cell Carcinoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Seminal Vesicle&apos;)</deletedAxiom>
<newAxiom>&apos;Seminal Vesicle Squamous Cell Carcinoma&apos; EquivalentTo &apos;Malignant Seminal Vesicle Neoplasm&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162486 and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Seminal Vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C161638</classIRI>
<classLabel>Seminal Vesicle Leiomyoma</classLabel>
<deletedAxiom>&apos;Seminal Vesicle Leiomyoma&apos; EquivalentTo &apos;Seminal Vesicle Soft Tissue Neoplasm&apos; and &apos;Benign Seminal Vesicle Neoplasm&apos; and &apos;Leiomyoma&apos;</deletedAxiom>
<newAxiom>&apos;Seminal Vesicle Leiomyoma&apos; EquivalentTo &apos;Seminal Vesicle Soft Tissue Neoplasm&apos; and &apos;Benign Seminal Vesicle Neoplasm&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162494</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C161637</classIRI>
<classLabel>Seminal Vesicle Soft Tissue Neoplasm</classLabel>
<deletedAxiom>&apos;Seminal Vesicle Soft Tissue Neoplasm&apos; EquivalentTo &apos;Soft Tissue Neoplasm&apos; and &apos;Seminal Vesicle Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Seminal Vesicle&apos;)</deletedAxiom>
<newAxiom>&apos;Seminal Vesicle Soft Tissue Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162492 and &apos;Seminal Vesicle Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Seminal Vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C161641</classIRI>
<classLabel>Seminal Vesicle Leiomyosarcoma</classLabel>
<deletedAxiom>&apos;Seminal Vesicle Leiomyosarcoma&apos; EquivalentTo &apos;Seminal Vesicle Soft Tissue Neoplasm&apos; and &apos;Malignant Seminal Vesicle Neoplasm&apos; and &apos;Leiomyosarcoma&apos; and &apos;Soft Tissue Sarcoma&apos;</deletedAxiom>
<newAxiom>&apos;Seminal Vesicle Leiomyosarcoma&apos; EquivalentTo &apos;Seminal Vesicle Soft Tissue Neoplasm&apos; and &apos;Malignant Seminal Vesicle Neoplasm&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162495</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C161640</classIRI>
<classLabel>Seminal Vesicle Mammary-Type Myofibroblastoma</classLabel>
<deletedAxiom>&apos;Seminal Vesicle Mammary-Type Myofibroblastoma&apos; EquivalentTo &apos;Mammary-Type Myofibroblastoma&apos; and &apos;Seminal Vesicle Soft Tissue Neoplasm&apos; and &apos;Benign Seminal Vesicle Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Seminal Vesicle Mammary-Type Myofibroblastoma&apos; EquivalentTo &apos;Seminal Vesicle Soft Tissue Neoplasm&apos; and &apos;Benign Seminal Vesicle Neoplasm&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162500</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136486</classIRI>
<classLabel>Lung Adenocarcinoma In Situ</classLabel>
<newAxiom>&apos;Lung Adenocarcinoma In Situ&apos; SubClassOf &apos;Lesion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C161607</classIRI>
<classLabel>Prostate Wilms Tumor</classLabel>
<deletedAxiom>&apos;Prostate Wilms Tumor&apos; EquivalentTo &apos;Wilms Tumor&apos; and &apos;Malignant Prostate Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Prostate Wilms Tumor&apos; EquivalentTo &apos;Wilms Tumor&apos; and &apos;Malignant Prostate Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Prostate Gland&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136649</classIRI>
<classLabel>Recurrent Cervical Squamous Cell Carcinoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Recurrent Cervical Squamous Cell Carcinoma, Not Otherwise Specified&apos; EquivalentTo &apos;Cervical Squamous Cell Carcinoma, Not Otherwise Specified&apos; and &apos;Recurrent Cervical Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Cervical Squamous Cell Carcinoma, Not Otherwise Specified&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162652 and &apos;Cervical Squamous Cell Carcinoma, Not Otherwise Specified&apos; and &apos;Recurrent Cervical Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C161586</classIRI>
<classLabel>Advanced Clear Cell Sarcoma of Soft Tissue</classLabel>
<deletedAxiom>&apos;Advanced Clear Cell Sarcoma of Soft Tissue&apos; EquivalentTo &apos;Advanced Sarcoma&apos; and &apos;Metastatic Clear Cell Sarcoma of Soft Tissue&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Clear Cell Sarcoma of Soft Tissue&apos; EquivalentTo &apos;Metastatic Clear Cell Sarcoma of Soft Tissue&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162194</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162117</classIRI>
<classLabel>Unresectable Rectal Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Unresectable Rectal Adenocarcinoma&apos; EquivalentTo &apos;Unresectable Digestive System Adenocarcinoma&apos; and &apos;Rectal Adenocarcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Unresectable Rectal Adenocarcinoma&apos; EquivalentTo &apos;Unresectable Digestive System Adenocarcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162600 and &apos;Rectal Adenocarcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162116</classIRI>
<classLabel>Unresectable Colon Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Unresectable Colon Adenocarcinoma&apos; EquivalentTo &apos;Unresectable Digestive System Adenocarcinoma&apos; and &apos;Colon Adenocarcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Unresectable Colon Adenocarcinoma&apos; EquivalentTo &apos;Unresectable Digestive System Adenocarcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162600 and &apos;Colon Adenocarcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C71616</classIRI>
<classLabel>CD13-Positive Neoplastic Cells Present</classLabel>
<newAxiom>&apos;CD13-Positive Neoplastic Cells Present&apos; SubClassOf &apos;CD13 Positive&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162050</classIRI>
<classLabel>Was Another CD Antigen Tested</classLabel>
<deletedAxiom>&apos;Was Another CD Antigen Tested&apos; SubClassOf &apos;CPTAC Questions&apos;</deletedAxiom>
<newAxiom>&apos;Was Another CD Antigen Tested&apos; SubClassOf &apos;Was Additional Testing Performed&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C71720</classIRI>
<classLabel>Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System</classLabel>
<deletedAxiom>&apos;Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System&apos; EquivalentTo &apos;Central Nervous System B-Cell Non-Hodgkin Lymphoma&apos; and &apos;Diffuse Large B-Cell Lymphoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System&apos; EquivalentTo &apos;Central Nervous System B-Cell Non-Hodgkin Lymphoma&apos; and &apos;Diffuse Large B-Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142868</classIRI>
<classLabel>Advanced Microsatellite Stable Colorectal Carcinoma</classLabel>
<deletedAxiom>&apos;Advanced Microsatellite Stable Colorectal Carcinoma&apos; EquivalentTo &apos;Metastatic Microsatellite Stable Colorectal Carcinoma&apos; and &apos;Advanced Digestive System Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Microsatellite Stable Colorectal Carcinoma&apos; EquivalentTo &apos;Metastatic Microsatellite Stable Colorectal Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162475</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66748</classIRI>
<classLabel>Testicular Sex Cord-Gonadal Stromal Tumor, Incompletely Differentiated</classLabel>
<deletedAxiom>&apos;Testicular Sex Cord-Gonadal Stromal Tumor, Incompletely Differentiated&apos; SubClassOf &apos;Testicular Sex Cord-Stromal Tumor&apos;</deletedAxiom>
<newAxiom>&apos;Testicular Sex Cord-Gonadal Stromal Tumor, Incompletely Differentiated&apos; EquivalentTo &apos;Testicular Sex Cord-Stromal Tumor&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Tissue Differentiation Uncertain&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66991</classIRI>
<classLabel>Testicular Sex Cord-Gonadal Stromal Tumor, Mixed Forms</classLabel>
<deletedAxiom>&apos;Testicular Sex Cord-Gonadal Stromal Tumor, Mixed Forms&apos; SubClassOf &apos;Testicular Sex Cord-Stromal Tumor&apos;</deletedAxiom>
<newAxiom>&apos;Testicular Sex Cord-Gonadal Stromal Tumor, Mixed Forms&apos; EquivalentTo &apos;Testicular Sex Cord-Stromal Tumor&apos; and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Granulosa Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Sertoli Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Leydig Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C52589</classIRI>
<classLabel>Buccal Surface</classLabel>
<newAxiom>&apos;Buccal Surface&apos; SubClassOf &apos;Tooth Part&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C52591</classIRI>
<classLabel>Occlusal Surface</classLabel>
<newAxiom>&apos;Occlusal Surface&apos; SubClassOf &apos;Tooth Part&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C52590</classIRI>
<classLabel>Mesial Surface</classLabel>
<newAxiom>&apos;Mesial Surface&apos; SubClassOf &apos;Tooth Part&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27718</classIRI>
<classLabel>Human Papillomavirus-Related Malignant Neoplasm</classLabel>
<deletedAxiom>&apos;Human Papillomavirus-Related Malignant Neoplasm&apos; EquivalentTo &apos;Virus-Related Malignant Neoplasm&apos; and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Human Papillomavirus Infection&apos;)</deletedAxiom>
<newAxiom>&apos;Human Papillomavirus-Related Malignant Neoplasm&apos; EquivalentTo &apos;Virus-Related Malignant Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Human Papillomavirus Positive&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Human Papillomavirus Infection&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160562</classIRI>
<classLabel>Equine Anti-thymocyte Globulin/Prednisone/Tacrolimus Regimen</classLabel>
<deletedAxiom>&apos;Equine Anti-thymocyte Globulin/Prednisone/Tacrolimus Regimen&apos; SubClassOf &apos;Chemotherapy_Regimen_Has_Component&apos; some &apos;Horse Anti-thymocyte Globulin&apos;</deletedAxiom>
<newAxiom>&apos;Equine Anti-thymocyte Globulin/Prednisone/Tacrolimus Regimen&apos; SubClassOf &apos;Chemotherapy_Regimen_Has_Component&apos; some &apos;Equine Thymocyte Immune Globulin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160559</classIRI>
<classLabel>Rabbit Anti-thymocyte Globulin/Prednisone/Tacrolimus Regimen</classLabel>
<deletedAxiom>&apos;Rabbit Anti-thymocyte Globulin/Prednisone/Tacrolimus Regimen&apos; SubClassOf &apos;Chemotherapy_Regimen_Has_Component&apos; some &apos;Rabbit Anti-Thymocyte Globulin&apos;</deletedAxiom>
<newAxiom>&apos;Rabbit Anti-thymocyte Globulin/Prednisone/Tacrolimus Regimen&apos; SubClassOf &apos;Chemotherapy_Regimen_Has_Component&apos; some &apos;Lapine T-Lymphocyte Immune Globulin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160744</classIRI>
<classLabel>DREAM Complex</classLabel>
<newAxiom>&apos;DREAM Complex&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Regulation&apos;</newAxiom>
<newAxiom>&apos;DREAM Complex&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Cycle Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160505</classIRI>
<classLabel>Antithymocyte Globulin Rabbit/Tacrolimus Regimen</classLabel>
<deletedAxiom>&apos;Antithymocyte Globulin Rabbit/Tacrolimus Regimen&apos; SubClassOf &apos;Chemotherapy_Regimen_Has_Component&apos; some &apos;Rabbit Anti-Thymocyte Globulin&apos;</deletedAxiom>
<newAxiom>&apos;Antithymocyte Globulin Rabbit/Tacrolimus Regimen&apos; SubClassOf &apos;Chemotherapy_Regimen_Has_Component&apos; some &apos;Lapine T-Lymphocyte Immune Globulin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160511</classIRI>
<classLabel>Horse Antithymocyte Globulin/Tacrolimus Regimen</classLabel>
<deletedAxiom>&apos;Horse Antithymocyte Globulin/Tacrolimus Regimen&apos; SubClassOf &apos;Chemotherapy_Regimen_Has_Component&apos; some &apos;Horse Anti-thymocyte Globulin&apos;</deletedAxiom>
<newAxiom>&apos;Horse Antithymocyte Globulin/Tacrolimus Regimen&apos; SubClassOf &apos;Chemotherapy_Regimen_Has_Component&apos; some &apos;Equine Thymocyte Immune Globulin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160423</classIRI>
<classLabel>Peritoneal Surface</classLabel>
<deletedAxiom>&apos;Peritoneal Surface&apos; SubClassOf &apos;Biospecimen&apos;</deletedAxiom>
<newAxiom>&apos;Peritoneal Surface&apos; SubClassOf &apos;Anatomic Surface&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160174</classIRI>
<classLabel>Was an ATRX Mutation Identified</classLabel>
<deletedAxiom>&apos;Was an ATRX Mutation Identified&apos; SubClassOf &apos;CPTAC Questions&apos;</deletedAxiom>
<newAxiom>&apos;Was an ATRX Mutation Identified&apos; SubClassOf &apos;Were Molecular Abnormalities Detected&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160172</classIRI>
<classLabel>Was an IDH Family Mutation Identified</classLabel>
<deletedAxiom>&apos;Was an IDH Family Mutation Identified&apos; SubClassOf &apos;CPTAC Questions&apos;</deletedAxiom>
<newAxiom>&apos;Was an IDH Family Mutation Identified&apos; SubClassOf &apos;Were Molecular Abnormalities Detected&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160171</classIRI>
<classLabel>Was a BRAF Mutation Identified</classLabel>
<deletedAxiom>&apos;Was a BRAF Mutation Identified&apos; SubClassOf &apos;CPTAC Questions&apos;</deletedAxiom>
<newAxiom>&apos;Was a BRAF Mutation Identified&apos; SubClassOf &apos;Were Molecular Abnormalities Detected&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160177</classIRI>
<classLabel>Was a TP53 Mutation Identified</classLabel>
<deletedAxiom>&apos;Was a TP53 Mutation Identified&apos; SubClassOf &apos;CPTAC Questions&apos;</deletedAxiom>
<newAxiom>&apos;Was a TP53 Mutation Identified&apos; SubClassOf &apos;Were Molecular Abnormalities Detected&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160176</classIRI>
<classLabel>Was a PTEN Mutation Identified</classLabel>
<deletedAxiom>&apos;Was a PTEN Mutation Identified&apos; SubClassOf &apos;CPTAC Questions&apos;</deletedAxiom>
<newAxiom>&apos;Was a PTEN Mutation Identified&apos; SubClassOf &apos;Were Molecular Abnormalities Detected&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160175</classIRI>
<classLabel>Was an EGFR Amplification Identified</classLabel>
<deletedAxiom>&apos;Was an EGFR Amplification Identified&apos; SubClassOf &apos;CPTAC Questions&apos;</deletedAxiom>
<newAxiom>&apos;Was an EGFR Amplification Identified&apos; SubClassOf &apos;Were Molecular Abnormalities Detected&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160283</classIRI>
<classLabel>Follow-Up Form Outcome Measure of Success Unknown</classLabel>
<deletedAxiom>&apos;Follow-Up Form Outcome Measure of Success Unknown&apos; SubClassOf &apos;CPTAC Responses&apos;</deletedAxiom>
<newAxiom>&apos;Follow-Up Form Outcome Measure of Success Unknown&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136411</classIRI>
<classLabel>Blasts 5 Percent or More of Bone Marrow Nucleated Cells</classLabel>
<deletedAxiom>&apos;Blasts 5 Percent or More of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blasts 0.1 Percent or More of Bone Marrow Nucleated Cells&apos;</deletedAxiom>
<newAxiom>&apos;Blasts 5 Percent or More of Bone Marrow Nucleated Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162512</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C72561</classIRI>
<classLabel>CD45-Positive Neoplastic Cells Present</classLabel>
<newAxiom>&apos;CD45-Positive Neoplastic Cells Present&apos; SubClassOf &apos;PTPRC Positive&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C161010</classIRI>
<classLabel>Pathologic T Category</classLabel>
<deletedAxiom>&apos;Pathologic T Category&apos; SubClassOf &apos;Pathologic Primary Tumor TNM Finding&apos;</deletedAxiom>
<newAxiom>&apos;Pathologic T Category&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9481</classIRI>
<classLabel>Primary Carcinoma</classLabel>
<deletedAxiom>&apos;Primary Carcinoma&apos; EquivalentTo &apos;Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Carcinoma&apos; EquivalentTo &apos;Carcinoma&apos; and &apos;Non-Metastatic Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9373</classIRI>
<classLabel>Adult Brain Medulloblastoma</classLabel>
<deletedAxiom>&apos;Adult Brain Medulloblastoma&apos; EquivalentTo &apos;Adult Medulloblastoma&apos; and &apos;Primary Malignant Brain Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Brain&apos;)</deletedAxiom>
<newAxiom>&apos;Adult Brain Medulloblastoma&apos; EquivalentTo &apos;Malignant Brain Neoplasm&apos; and &apos;Adult Medulloblastoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Brain&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9301</classIRI>
<classLabel>Central Nervous System Lymphoma</classLabel>
<deletedAxiom>&apos;Central Nervous System Lymphoma&apos; EquivalentTo &apos;Malignant Central Nervous System Neoplasm&apos; and &apos;Central Nervous System Hematopoietic Neoplasm&apos; and &apos;Lymphoma by Site&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Central Nervous System&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Central Nervous System Lymphoma&apos; EquivalentTo &apos;Malignant Central Nervous System Neoplasm&apos; and &apos;Central Nervous System Hematopoietic Neoplasm&apos; and &apos;Lymphoma by Site&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Central Nervous System&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116894</classIRI>
<classLabel>FGFR/VEGFR/PDGFR/FLT3/SRC Inhibitor XL999</classLabel>
<deletedAxiom>&apos;FGFR/VEGFR/PDGFR/FLT3/SRC Inhibitor XL999&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;FGFR/VEGFR/PDGFR/FLT3/SRC Inhibitor XL999&apos; SubClassOf &apos;FLT3 Inhibitor&apos;</newAxiom>
<newAxiom>&apos;FGFR/VEGFR/PDGFR/FLT3/SRC Inhibitor XL999&apos; SubClassOf &apos;PDGFR Inhibitor&apos;</newAxiom>
<newAxiom>&apos;FGFR/VEGFR/PDGFR/FLT3/SRC Inhibitor XL999&apos; SubClassOf &apos;VEGFR Tyrosine Kinase Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9275</classIRI>
<classLabel>Primary Angiosarcoma</classLabel>
<deletedAxiom>&apos;Primary Angiosarcoma&apos; EquivalentTo &apos;Angiosarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Angiosarcoma&apos; EquivalentTo &apos;Angiosarcoma&apos; and &apos;Non-Metastatic Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9176</classIRI>
<classLabel>Non-Metastatic Gestational Trophoblastic Tumor</classLabel>
<deletedAxiom>&apos;Non-Metastatic Gestational Trophoblastic Tumor&apos; EquivalentTo &apos;Gestational Trophoblastic Tumor&apos; and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Cytotrophoblastic Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Syncytiotrophoblastic Giant Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Intermediate Type Trophoblastic Cell&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Gestational Trophoblastic Tumor&apos; EquivalentTo &apos;Non-Metastatic Neoplasm&apos; and &apos;Gestational Trophoblastic Tumor&apos; and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Cytotrophoblastic Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Syncytiotrophoblastic Giant Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Intermediate Type Trophoblastic Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9117</classIRI>
<classLabel>Recurrent Metastatic Squamous Cell Carcinoma in the Neck with Occult Primary</classLabel>
<deletedAxiom>&apos;Recurrent Metastatic Squamous Cell Carcinoma in the Neck with Occult Primary&apos; EquivalentTo &apos;Recurrent Malignant Head and Neck Neoplasm&apos; and &apos;Squamous Cell Carcinoma Metastatic in the Neck with Occult Primary&apos; and &apos;Recurrent Carcinoma of Unknown Primary&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Metastatic Squamous Cell Carcinoma in the Neck with Occult Primary&apos; EquivalentTo &apos;Recurrent Malignant Head and Neck Neoplasm&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162652 and &apos;Squamous Cell Carcinoma Metastatic in the Neck with Occult Primary&apos; and &apos;Recurrent Carcinoma of Unknown Primary&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116408</classIRI>
<classLabel>ABCA1 Gene</classLabel>
<newAxiom>&apos;ABCA1 Gene&apos; SubClassOf &apos;Translocase Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116410</classIRI>
<classLabel>ATP-Binding Cassette Sub-Family A Member 1</classLabel>
<deletedAxiom>&apos;ATP-Binding Cassette Sub-Family A Member 1&apos; EquivalentTo &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;RXR and RAR Heterodimerization with Other Nuclear Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Endosome&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intracellular Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Lipid Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cholesterol Homeostasis&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ABCA1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;ATP-Binding Cassette Sub-Family A Member 1&apos; EquivalentTo &apos;Translocase&apos; and &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;RXR and RAR Heterodimerization with Other Nuclear Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Endosome&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intracellular Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Lipid Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cholesterol Homeostasis&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ABCA1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67260</classIRI>
<classLabel>Ten Million Cells per Kilogram</classLabel>
<deletedAxiom>&apos;Ten Million Cells per Kilogram&apos; SubClassOf &apos;Unit of Cell Concentration&apos;</deletedAxiom>
<newAxiom>&apos;Ten Million Cells per Kilogram&apos; SubClassOf &apos;Cells per Kilogram&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67259</classIRI>
<classLabel>Million Cells per Kilogram</classLabel>
<deletedAxiom>&apos;Million Cells per Kilogram&apos; SubClassOf &apos;Unit of Cell Concentration&apos;</deletedAxiom>
<newAxiom>&apos;Million Cells per Kilogram&apos; SubClassOf &apos;Cells per Kilogram&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67258</classIRI>
<classLabel>Hundred Thousand Cells per Kilogram</classLabel>
<deletedAxiom>&apos;Hundred Thousand Cells per Kilogram&apos; SubClassOf &apos;Unit of Cell Concentration&apos;</deletedAxiom>
<newAxiom>&apos;Hundred Thousand Cells per Kilogram&apos; SubClassOf &apos;Cells per Kilogram&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67257</classIRI>
<classLabel>Ten Thousand Cells per Kilogram</classLabel>
<deletedAxiom>&apos;Ten Thousand Cells per Kilogram&apos; SubClassOf &apos;Unit of Cell Concentration&apos;</deletedAxiom>
<newAxiom>&apos;Ten Thousand Cells per Kilogram&apos; SubClassOf &apos;Cells per Kilogram&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116524</classIRI>
<classLabel>Computer-Assisted Smoking Cessation Intervention</classLabel>
<deletedAxiom>&apos;Computer-Assisted Smoking Cessation Intervention&apos; SubClassOf &apos;Smoking Cessation&apos;</deletedAxiom>
<newAxiom>&apos;Computer-Assisted Smoking Cessation Intervention&apos; SubClassOf &apos;Smoking Cessation Intervention&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67383</classIRI>
<classLabel>Epidermolysis Bullosa</classLabel>
<newAxiom>&apos;Epidermolysis Bullosa&apos; SubClassOf &apos;Rare Non-Neoplastic Disorder&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C155821</classIRI>
<classLabel>Age-Related Clonal Hematopoiesis</classLabel>
<deletedAxiom>&apos;Age-Related Clonal Hematopoiesis&apos; SubClassOf &apos;Other Finding&apos;</deletedAxiom>
<newAxiom>&apos;Age-Related Clonal Hematopoiesis&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162188 and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162191)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67495</classIRI>
<classLabel>FLT3 Tyrosine Kinase Domain Point Mutation</classLabel>
<deletedAxiom>&apos;FLT3 Tyrosine Kinase Domain Point Mutation&apos; SubClassOf &apos;FLT3 Gene Mutation&apos;</deletedAxiom>
<newAxiom>&apos;FLT3 Tyrosine Kinase Domain Point Mutation&apos; SubClassOf &apos;Point Mutation&apos;</newAxiom>
<newAxiom>&apos;FLT3 Tyrosine Kinase Domain Point Mutation&apos; SubClassOf &apos;FLT3 Activation Loop Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C155953</classIRI>
<classLabel>Epididymal Papillary Cystadenoma</classLabel>
<deletedAxiom>&apos;Epididymal Papillary Cystadenoma&apos; EquivalentTo &apos;Papillary Cystadenoma&apos; and &apos;Benign Epididymal Neoplasm&apos; and &apos;Benign Epithelial Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Epididymal Papillary Cystadenoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162483 and &apos;Papillary Cystadenoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C92629</classIRI>
<classLabel>Central Nervous System Ganglioneuroblastoma</classLabel>
<deletedAxiom>&apos;Central Nervous System Ganglioneuroblastoma&apos; EquivalentTo &apos;Primary Cerebral Neoplasm&apos; and &apos;Ganglioneuroblastoma&apos; and &apos;Malignant Cerebral Neoplasm&apos; and &apos;Primary Malignant Brain Neoplasm&apos; and &apos;Central Nervous System Embryonal Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Central Nervous System Ganglioneuroblastoma&apos; EquivalentTo &apos;Ganglioneuroblastoma&apos; and &apos;Malignant Cerebral Neoplasm&apos; and &apos;Cerebral Neoplasm&apos; and &apos;Central Nervous System Embryonal Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cerebral Hemisphere&apos;)</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162521</classIRI>
<classLabel>Anti-ICOS Monoclonal Antibody KY1044</classLabel>
<newAxiom>'Anti-ICOS Monoclonal Antibody KY1044' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-ICOS Monoclonal Antibody KY1044' SubClassOf 'Anti-ICOS Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162520</classIRI>
<classLabel>PLOD2 wt Allele</classLabel>
<newAxiom>'PLOD2 wt Allele' EquivalentTo 'PLOD2 Gene' and ('Gene_Is_Element_In_Pathway' some 'Lysine Degradation Pathway') and ('Gene_In_Chromosomal_Location' some '3q24')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162525</classIRI>
<classLabel>Tubulin Polymerization Inhibitor AEZS 112</classLabel>
<newAxiom>'Tubulin Polymerization Inhibitor AEZS 112' SubClassOf 'Tubulin Binding Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162524</classIRI>
<classLabel>Recombinant Human Plasminogen Kringle 5 Domain ABT 828</classLabel>
<newAxiom>'Recombinant Human Plasminogen Kringle 5 Domain ABT 828' SubClassOf 'Angiogenesis Inhibitor'</newAxiom>
<newAxiom>'Recombinant Human Plasminogen Kringle 5 Domain ABT 828' SubClassOf 'Antineoplastic Biological Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162523</classIRI>
<classLabel>COL7A1 Exon 73 Mutation</classLabel>
<newAxiom>'COL7A1 Exon 73 Mutation' SubClassOf 'COL7A1 Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162522</classIRI>
<classLabel>Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 2</classLabel>
<newAxiom>'Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 2' EquivalentTo 'Oxidoreductase' and ('Gene_Product_Is_Element_In_Pathway' some 'Lysine Degradation Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Rough Endoplasmic Reticulum') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Oxidation/Reduction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Post-Translational Modification') and ('Gene_Product_Encoded_By_Gene' some 'PLOD2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162529</classIRI>
<classLabel>Colon Polyp Observed During Examination</classLabel>
<newAxiom>'Colon Polyp Observed During Examination' SubClassOf 'Abnormal Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162528</classIRI>
<classLabel>Anti-BCMA Antibody-drug Conjugate AMG 224</classLabel>
<newAxiom>'Anti-BCMA Antibody-drug Conjugate AMG 224' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
<newAxiom>'Anti-BCMA Antibody-drug Conjugate AMG 224' SubClassOf 'Immunotoxin'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162527</classIRI>
<classLabel>Tubulin Inhibitor ALB-109564</classLabel>
<newAxiom>'Tubulin Inhibitor ALB-109564' SubClassOf 'Tubulin Binding Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162526</classIRI>
<classLabel>30 Day Prior Medications</classLabel>
<newAxiom>'30 Day Prior Medications' SubClassOf 'CPTAC Questions'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162532</classIRI>
<classLabel>Aurora kinase A/B inhibitor TT-00420</classLabel>
<newAxiom>'Aurora kinase A/B inhibitor TT-00420' SubClassOf 'Chemical_Or_Drug_Affects_Gene_Product' some 'Aurora Kinase A'</newAxiom>
<newAxiom>'Aurora kinase A/B inhibitor TT-00420' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Inhibition of Cell Proliferation'</newAxiom>
<newAxiom>'Aurora kinase A/B inhibitor TT-00420' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Enzyme Inhibition'</newAxiom>
<newAxiom>'Aurora kinase A/B inhibitor TT-00420' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Signal Transduction Inhibition'</newAxiom>
<newAxiom>'Aurora kinase A/B inhibitor TT-00420' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'Aurora kinase A/B inhibitor TT-00420' SubClassOf 'Aurora Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162531</classIRI>
<classLabel>Invasive Adenocarcinoma in Adenomatous Polyp</classLabel>
<newAxiom>'Invasive Adenocarcinoma in Adenomatous Polyp' EquivalentTo 'Adenocarcinoma in Adenomatous Polyp' and 'Invasive Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162530</classIRI>
<classLabel>cobas MPX Test</classLabel>
<newAxiom>'cobas MPX Test' SubClassOf 'Polymerase Chain Reaction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162536</classIRI>
<classLabel>Non-Human Papillomavirus-Related Penile Intraepithelial Neoplasia</classLabel>
<newAxiom>'Non-Human Papillomavirus-Related Penile Intraepithelial Neoplasia' EquivalentTo 'Penile Intraepithelial Neoplasia' and ('Disease_Has_Finding' some 'Human Papillomavirus Negative')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162535</classIRI>
<classLabel>IAP Inhibitor APG-1387</classLabel>
<newAxiom>'IAP Inhibitor APG-1387' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'IAP Inhibitor APG-1387' SubClassOf 'VEGFR Tyrosine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162534</classIRI>
<classLabel>Abdominal Surgery Patient</classLabel>
<newAxiom>'Abdominal Surgery Patient' SubClassOf 'Surgery Patient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162533</classIRI>
<classLabel>Src Kinase Inhibitor AP 23846</classLabel>
<newAxiom>'Src Kinase Inhibitor AP 23846' SubClassOf 'Tyrosine Kinase Inhibitor'</newAxiom>
<newAxiom>'Src Kinase Inhibitor AP 23846' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162539</classIRI>
<classLabel>Differentiated (Simplex) Penile Intraepithelial Neoplasia</classLabel>
<newAxiom>'Differentiated (Simplex) Penile Intraepithelial Neoplasia' EquivalentTo 'Non-Human Papillomavirus-Related Penile Intraepithelial Neoplasia' and ('Disease_May_Have_Associated_Disease' some 'Balanitis Xerotica Obliterans') and ('Disease_Excludes_Finding' some 'Severe Dysplasia')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162538</classIRI>
<classLabel>Refractory Gastroesophageal Junction Adenocarcinoma</classLabel>
<newAxiom>'Refractory Gastroesophageal Junction Adenocarcinoma' EquivalentTo 'Refractory Digestive System Carcinoma' and 'Refractory Adenocarcinoma' and 'Gastroesophageal Junction Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162537</classIRI>
<classLabel>Lorukafusp alfa</classLabel>
<newAxiom>'Lorukafusp alfa' SubClassOf 'Chemical_Or_Drug_Has_Mechanism_Of_Action' some 'Receptor Activation Process'</newAxiom>
<newAxiom>'Lorukafusp alfa' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'T-Cell Activation'</newAxiom>
<newAxiom>'Lorukafusp alfa' SubClassOf 'Immunoconjugate'</newAxiom>
<newAxiom>'Lorukafusp alfa' SubClassOf 'Chemical_Or_Drug_Has_Mechanism_Of_Action' some 'Antigen Binding'</newAxiom>
<newAxiom>'Lorukafusp alfa' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Immunopotentiation'</newAxiom>
<newAxiom>'Lorukafusp alfa' SubClassOf 'Chemical_Or_Drug_Affects_Cell_Type_Or_Tissue' some 'Cytotoxic T-Lymphocyte'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162509</classIRI>
<classLabel>Glucocorticoid Receptor Antagonist ORIC-101</classLabel>
<newAxiom>'Glucocorticoid Receptor Antagonist ORIC-101' SubClassOf 'Antineoplastic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162508</classIRI>
<classLabel>Pegylated Deoxycytidine Analogue DFP-14927</classLabel>
<newAxiom>'Pegylated Deoxycytidine Analogue DFP-14927' SubClassOf 'Pyrimidine Antagonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162503</classIRI>
<classLabel>Paratesticular Hemangioma</classLabel>
<newAxiom>'Paratesticular Hemangioma' EquivalentTo 'Paratesticular Soft Tissue Neoplasm' and 'Hemangioma' and 'Benign Soft Tissue Neoplasm' and 'Benign Male Reproductive System Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162502</classIRI>
<classLabel>Paratesticular Schwannoma</classLabel>
<newAxiom>'Paratesticular Schwannoma' EquivalentTo 'Paratesticular Soft Tissue Neoplasm' and 'Peripheral Nerve Schwannoma' and 'Benign Male Reproductive System Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162501</classIRI>
<classLabel>Paratesticular Deep "Aggressive" Angiomyxoma</classLabel>
<newAxiom>'Paratesticular Deep "Aggressive" Angiomyxoma' EquivalentTo 'Paratesticular Soft Tissue Neoplasm' and 'Benign Male Reproductive System Neoplasm' and 'Deep "Aggressive" Angiomyxoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162500</classIRI>
<classLabel>Paratesticular Mammary-Type Myofibroblastoma</classLabel>
<newAxiom>'Paratesticular Mammary-Type Myofibroblastoma' EquivalentTo 'Mammary-Type Myofibroblastoma' and 'Paratesticular Soft Tissue Neoplasm' and 'Benign Male Reproductive System Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162507</classIRI>
<classLabel>Abemaciclib Mesylate</classLabel>
<newAxiom>'Abemaciclib Mesylate' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'Abemaciclib Mesylate' SubClassOf 'Cyclin-Dependent Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162506</classIRI>
<classLabel>Autologous BCMA-targeted CAR T Cells LCAR-B4822M</classLabel>
<newAxiom>'Autologous BCMA-targeted CAR T Cells LCAR-B4822M' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Autologous BCMA-targeted CAR T Cells LCAR-B4822M' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous BCMA-targeted CAR T Cells LCAR-B4822M' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162505</classIRI>
<classLabel>Anti-CTLA-4 Monoclonal Antibody ADU-1604</classLabel>
<newAxiom>'Anti-CTLA-4 Monoclonal Antibody ADU-1604' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-CTLA-4 Monoclonal Antibody ADU-1604' SubClassOf 'Anti-CTLA-4 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162504</classIRI>
<classLabel>Anti-PD-L1 Monoclonal Antibody ZKAB001</classLabel>
<newAxiom>'Anti-PD-L1 Monoclonal Antibody ZKAB001' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-PD-L1 Monoclonal Antibody ZKAB001' SubClassOf 'Anti-PD-L1 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162519</classIRI>
<classLabel>PLOD2 Gene</classLabel>
<newAxiom>'PLOD2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Oxidation/Reduction'</newAxiom>
<newAxiom>'PLOD2 Gene' SubClassOf 'Oxidoreductase Gene'</newAxiom>
<newAxiom>'PLOD2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Post-Translational Modification'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162510</classIRI>
<classLabel>MYCN Negative</classLabel>
<newAxiom>'MYCN Negative' SubClassOf 'Negative Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162514</classIRI>
<classLabel>Deleterious GNA11 Gene Mutation</classLabel>
<newAxiom>'Deleterious GNA11 Gene Mutation' SubClassOf 'Deleterious Mutation'</newAxiom>
<newAxiom>'Deleterious GNA11 Gene Mutation' SubClassOf 'GNA11 Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162513</classIRI>
<classLabel>KMT2A Gene Mutation</classLabel>
<newAxiom>'KMT2A Gene Mutation' SubClassOf 'Gene Mutant'</newAxiom>
<newAxiom>'KMT2A Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'KMT2A Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162512</classIRI>
<classLabel>Blasts 1 Percent or More of Bone Marrow Nucleated Cells</classLabel>
<newAxiom>'Blasts 1 Percent or More of Bone Marrow Nucleated Cells' SubClassOf 'Blasts 0.1 Percent or More of Bone Marrow Nucleated Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162511</classIRI>
<classLabel>MYC Negative</classLabel>
<newAxiom>'MYC Negative' SubClassOf 'Negative Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162518</classIRI>
<classLabel>Nicotine Metabolite Ratio Measurement</classLabel>
<newAxiom>'Nicotine Metabolite Ratio Measurement' SubClassOf 'Chemistry Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162517</classIRI>
<classLabel>Alpha-Fetoprotein Positive</classLabel>
<newAxiom>'Alpha-Fetoprotein Positive' SubClassOf 'AFP Level Finding'</newAxiom>
<newAxiom>'Alpha-Fetoprotein Positive' SubClassOf 'Positive Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162516</classIRI>
<classLabel>Somatic Hypermutation</classLabel>
<newAxiom>'Somatic Hypermutation' SubClassOf 'Hypermutation Phenotype'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162515</classIRI>
<classLabel>Loss of MSH2 Expression</classLabel>
<newAxiom>'Loss of MSH2 Expression' SubClassOf 'Protein Deregulation'</newAxiom>
<newAxiom>'Loss of MSH2 Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'MSH2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162590</classIRI>
<classLabel>Penile Myointimoma</classLabel>
<newAxiom>'Penile Myointimoma' EquivalentTo 'Penile Soft Tissue Neoplasm' and 'Benign Penile Neoplasm' and 'Benign Soft Tissue Neoplasm' and ('Disease_Has_Abnormal_Cell' some 'Neoplastic Spindle-Shaped Myofibroblast') and ('Disease_Has_Finding' some 'Intravascular Myofibroblastic Proliferation')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162583</classIRI>
<classLabel>Penile Leiomyoma</classLabel>
<newAxiom>'Penile Leiomyoma' EquivalentTo 'Penile Soft Tissue Neoplasm' and 'Leiomyoma' and 'Benign Penile Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162582</classIRI>
<classLabel>Penile Glomus Tumor</classLabel>
<newAxiom>'Penile Glomus Tumor' EquivalentTo 'Penile Soft Tissue Neoplasm' and 'Glomus Tumor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162581</classIRI>
<classLabel>Penile Epithelioid Hemangioendothelioma</classLabel>
<newAxiom>'Penile Epithelioid Hemangioendothelioma' EquivalentTo 'Penile Soft Tissue Neoplasm' and 'Penile Vascular Disorder' and 'Epithelioid Hemangioendothelioma' and 'Malignant Soft Tissue Neoplasm' and 'Malignant Penile Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162580</classIRI>
<classLabel>Penile Epithelioid Hemangioma</classLabel>
<newAxiom>'Penile Epithelioid Hemangioma' EquivalentTo 'Penile Hemangioma' and 'Skin Epithelioid Hemangioma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162587</classIRI>
<classLabel>Penile Neurofibroma</classLabel>
<newAxiom>'Penile Neurofibroma' EquivalentTo 'Neurofibroma' and 'Benign Penile Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162586</classIRI>
<classLabel>Penile Schwannoma</classLabel>
<newAxiom>'Penile Schwannoma' EquivalentTo 'Benign Penile Neoplasm' and 'Peripheral Nerve Schwannoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162585</classIRI>
<classLabel>Penile Leiomyosarcoma</classLabel>
<newAxiom>'Penile Leiomyosarcoma' EquivalentTo 'Leiomyosarcoma' and 'Penile Sarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162584</classIRI>
<classLabel>Penile Malignant Peripheral Nerve Sheath Tumor</classLabel>
<newAxiom>'Penile Malignant Peripheral Nerve Sheath Tumor' EquivalentTo 'Malignant Peripheral Nerve Sheath Tumor' and 'Penile Sarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162589</classIRI>
<classLabel>Penile Undifferentiated Pleomorphic Sarcoma</classLabel>
<newAxiom>'Penile Undifferentiated Pleomorphic Sarcoma' EquivalentTo 'Undifferentiated Pleomorphic Sarcoma' and 'Penile Sarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162588</classIRI>
<classLabel>Penile Rhabdomyosarcoma</classLabel>
<newAxiom>'Penile Rhabdomyosarcoma' EquivalentTo 'Rhabdomyosarcoma' and 'Penile Sarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162594</classIRI>
<classLabel>Metastatic Malignant Neoplasm in the Head and Neck</classLabel>
<newAxiom>'Metastatic Malignant Neoplasm in the Head and Neck' EquivalentTo 'Metastatic Malignant Neoplasm' and 'Malignant Head and Neck Neoplasm' and ('Disease_Has_Metastatic_Anatomic_Site' some 'Head and Neck')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162592</classIRI>
<classLabel>Penile Lymphangioma</classLabel>
<newAxiom>'Penile Lymphangioma' EquivalentTo 'Penile Soft Tissue Neoplasm' and 'Skin Lymphangioma' and 'Benign Penile Neoplasm' and 'Penile Vascular Disorder' and 'Benign Soft Tissue Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162591</classIRI>
<classLabel>Intravascular Myofibroblastic Proliferation</classLabel>
<newAxiom>'Intravascular Myofibroblastic Proliferation' SubClassOf 'Vascular Morphologic Change'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162598</classIRI>
<classLabel>Additional Surgery for new Loco-Regional Tumor Event Not Evaluated</classLabel>
<newAxiom>'Additional Surgery for new Loco-Regional Tumor Event Not Evaluated' SubClassOf 'CPTAC Responses'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162597</classIRI>
<classLabel>Protein Expression Analysis by Immunohistochemistry</classLabel>
<newAxiom>'Protein Expression Analysis by Immunohistochemistry' SubClassOf 'Protein Expression Analysis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162596</classIRI>
<classLabel>Was In Situ Hybridization Performed</classLabel>
<newAxiom>'Was In Situ Hybridization Performed' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162595</classIRI>
<classLabel>Head and Neck Carcinoma of Unknown Primary</classLabel>
<newAxiom>'Head and Neck Carcinoma of Unknown Primary' EquivalentTo 'Metastatic Malignant Neoplasm in the Head and Neck' and 'Carcinoma of Unknown Primary'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162599</classIRI>
<classLabel>Was RT-PCR Performed</classLabel>
<newAxiom>'Was RT-PCR Performed' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162565</classIRI>
<classLabel>Lutetium Lu 177 Lilotomab-satetraxetan</classLabel>
<newAxiom>'Lutetium Lu 177 Lilotomab-satetraxetan' SubClassOf 'Immunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162564</classIRI>
<classLabel>Primary Peritoneal Transitional Cell Carcinoma</classLabel>
<newAxiom>'Primary Peritoneal Transitional Cell Carcinoma' EquivalentTo 'Transitional Cell Carcinoma' and 'Primary Peritoneal Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162563</classIRI>
<classLabel>Lutetium Lu-177 Rituximab</classLabel>
<newAxiom>'Lutetium Lu-177 Rituximab' SubClassOf 'Antineoplastic Radiopharmaceutical Agent'</newAxiom>
<newAxiom>'Lutetium Lu-177 Rituximab' SubClassOf 'Radioconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162562</classIRI>
<classLabel>Primary Peritoneal Undifferentiated Carcinoma</classLabel>
<newAxiom>'Primary Peritoneal Undifferentiated Carcinoma' EquivalentTo 'Undifferentiated Carcinoma' and 'Primary Peritoneal Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162569</classIRI>
<classLabel>Non-Metastatic Head and Neck Carcinoma</classLabel>
<newAxiom>'Non-Metastatic Head and Neck Carcinoma' EquivalentTo 'Head and Neck Carcinoma' and 'Non-Metastatic Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162568</classIRI>
<classLabel>Infigratinib Mesylate</classLabel>
<newAxiom>'Infigratinib Mesylate' SubClassOf 'Angiogenesis Inhibitor'</newAxiom>
<newAxiom>'Infigratinib Mesylate' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'Infigratinib Mesylate' SubClassOf 'Tyrosine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162567</classIRI>
<classLabel>Luminespib Mesylate</classLabel>
<newAxiom>'Luminespib Mesylate' SubClassOf 'HSP90 Inhibitor'</newAxiom>
<newAxiom>'Luminespib Mesylate' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Positive Regulation of Apoptosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162566</classIRI>
<classLabel>Primary Peritoneal Clear Cell Carcinoma</classLabel>
<newAxiom>'Primary Peritoneal Clear Cell Carcinoma' EquivalentTo 'Clear Cell Adenocarcinoma' and 'Primary Peritoneal Carcinoma' and ('Disease_Has_Abnormal_Cell' some 'Malignant Hobnail Cell')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162572</classIRI>
<classLabel>Metastatic Merkel Cell Carcinoma</classLabel>
<newAxiom>'Metastatic Merkel Cell Carcinoma' EquivalentTo 'Metastatic Neuroendocrine Carcinoma' and 'Merkel Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162570</classIRI>
<classLabel>Non-Metastatic Lung Carcinoma</classLabel>
<newAxiom>'Non-Metastatic Lung Carcinoma' EquivalentTo 'Lung Carcinoma' and 'Non-Metastatic Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162576</classIRI>
<classLabel>ProMark Proteomic Prognostic Test</classLabel>
<newAxiom>'ProMark Proteomic Prognostic Test' SubClassOf 'Molecular Profiling'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162575</classIRI>
<classLabel>99mTc Bone Scintography</classLabel>
<newAxiom>'99mTc Bone Scintography' SubClassOf 'Bone Scan'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162574</classIRI>
<classLabel>Penile Soft Tissue Neoplasm</classLabel>
<newAxiom>'Penile Soft Tissue Neoplasm' EquivalentTo 'Penile Neoplasm' and 'Soft Tissue Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Penis')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162573</classIRI>
<classLabel>Pan-FLT3/Pan-BTK Multi-kinase Inhibitor CG-806</classLabel>
<newAxiom>'Pan-FLT3/Pan-BTK Multi-kinase Inhibitor CG-806' SubClassOf 'BTK Inhibitor'</newAxiom>
<newAxiom>'Pan-FLT3/Pan-BTK Multi-kinase Inhibitor CG-806' SubClassOf 'FLT3 Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162579</classIRI>
<classLabel>Penile Hemangioma</classLabel>
<newAxiom>'Penile Hemangioma' EquivalentTo 'Penile Soft Tissue Neoplasm' and 'Benign Penile Neoplasm' and 'Penile Vascular Disorder' and 'Benign Soft Tissue Neoplasm' and 'Skin Hemangioma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162578</classIRI>
<classLabel>Penile Angiosarcoma</classLabel>
<newAxiom>'Penile Angiosarcoma' EquivalentTo 'Soft Tissue Angiosarcoma' and 'Penile Vascular Disorder' and 'Penile Sarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162577</classIRI>
<classLabel>Anti-HER-2 Bispecific Antibody KN026</classLabel>
<newAxiom>'Anti-HER-2 Bispecific Antibody KN026' SubClassOf 'Anti-HER2 Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-HER-2 Bispecific Antibody KN026' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162543</classIRI>
<classLabel>Warty (Bowenoid) Penile Intraepithelial Neoplasia</classLabel>
<newAxiom>'Warty (Bowenoid) Penile Intraepithelial Neoplasia' EquivalentTo 'Human Papillomavirus-Related Penile Intraepithelial Neoplasia' and ('Disease_Has_Finding' some 'Squamous Papillomatosis') and ('Disease_Excludes_Finding' some 'Severe Dysplasia')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162542</classIRI>
<classLabel>Basaloid (Undifferentiated) Penile Intraepithelial Neoplasia</classLabel>
<newAxiom>'Basaloid (Undifferentiated) Penile Intraepithelial Neoplasia' EquivalentTo 'Human Papillomavirus-Related Penile Intraepithelial Neoplasia' and ('Disease_Has_Finding' some 'Severe Dysplasia') and ('Disease_Excludes_Finding' some 'Squamous Papillomatosis')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162541</classIRI>
<classLabel>Human Papillomavirus-Related Penile Intraepithelial Neoplasia</classLabel>
<newAxiom>'Human Papillomavirus-Related Penile Intraepithelial Neoplasia' EquivalentTo 'Penile Intraepithelial Neoplasia' and ('Disease_Has_Finding' some 'Human Papillomavirus Positive') and ('Disease_Has_Associated_Disease' some 'Human Papillomavirus Infection')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162540</classIRI>
<classLabel>Aranose</classLabel>
<newAxiom>'Aranose' SubClassOf 'Nitrosourea Compound'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162547</classIRI>
<classLabel>Penile Melanoma</classLabel>
<newAxiom>'Penile Melanoma' EquivalentTo 'Melanoma' and 'Malignant Penile Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Penis')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162546</classIRI>
<classLabel>Warty-Basaloid Penile Intraepithelial Neoplasia</classLabel>
<newAxiom>'Warty-Basaloid Penile Intraepithelial Neoplasia' EquivalentTo 'Human Papillomavirus-Related Penile Intraepithelial Neoplasia' and ('Disease_Has_Finding' some 'Severe Dysplasia') and ('Disease_Has_Finding' some 'Squamous Papillomatosis')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162545</classIRI>
<classLabel>Uroacitides</classLabel>
<newAxiom>'Uroacitides' SubClassOf 'Telomerase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162544</classIRI>
<classLabel>Zinostatin Stimalamer</classLabel>
<newAxiom>'Zinostatin Stimalamer' SubClassOf 'Immunotoxin'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162549</classIRI>
<classLabel>Metastatic Malignant Neoplasm in the Penis</classLabel>
<newAxiom>'Metastatic Malignant Neoplasm in the Penis' EquivalentTo 'Metastatic Malignant Neoplasm' and 'Malignant Penile Neoplasm' and ('Disease_Has_Metastatic_Anatomic_Site' some 'Penis')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162548</classIRI>
<classLabel>Penile Lymphoma</classLabel>
<newAxiom>'Penile Lymphoma' EquivalentTo 'Lymphoma by Site' and 'Malignant Penile Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162554</classIRI>
<classLabel>Pyrotinib Dimaleate</classLabel>
<newAxiom>'Pyrotinib Dimaleate' SubClassOf 'Tyrosine Kinase Inhibitor'</newAxiom>
<newAxiom>'Pyrotinib Dimaleate' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'Pyrotinib Dimaleate' SubClassOf 'Angiogenesis Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162553</classIRI>
<classLabel>Sitimagene Ceradenovec</classLabel>
<newAxiom>'Sitimagene Ceradenovec' SubClassOf 'Gene Therapy Agent'</newAxiom>
<newAxiom>'Sitimagene Ceradenovec' SubClassOf 'Gene Transfer or Gene Delivery Agent'</newAxiom>
<newAxiom>'Sitimagene Ceradenovec' SubClassOf 'Antineoplastic Biological Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162552</classIRI>
<classLabel>Theliatinib</classLabel>
<newAxiom>'Theliatinib' SubClassOf 'Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor'</newAxiom>
<newAxiom>'Theliatinib' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162551</classIRI>
<classLabel>Post-Operative Therapy Rounds Section</classLabel>
<newAxiom>'Post-Operative Therapy Rounds Section' SubClassOf 'Form Directive'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162558</classIRI>
<classLabel>B-Mode Ultrasound Imaging</classLabel>
<newAxiom>'B-Mode Ultrasound Imaging' SubClassOf 'Ultrasonography'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162557</classIRI>
<classLabel>Endobronchial Cryotherapy</classLabel>
<newAxiom>'Endobronchial Cryotherapy' SubClassOf 'Cryosurgery'</newAxiom>
<newAxiom>'Endobronchial Cryotherapy' SubClassOf 'Cryotherapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162556</classIRI>
<classLabel>Puquitinib Mesylate</classLabel>
<newAxiom>'Puquitinib Mesylate' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'Puquitinib Mesylate' SubClassOf 'Phosphatidylinositide 3-Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162555</classIRI>
<classLabel>Puquitinib</classLabel>
<newAxiom>'Puquitinib' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'Puquitinib' SubClassOf 'Phosphatidylinositide 3-Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162559</classIRI>
<classLabel>Acoustic Angiography</classLabel>
<newAxiom>'Acoustic Angiography' SubClassOf 'Ultrasonography'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162642</classIRI>
<classLabel>Unresectable Lung Non-Squamous Non-Small Cell Carcinoma</classLabel>
<newAxiom>'Unresectable Lung Non-Squamous Non-Small Cell Carcinoma' EquivalentTo 'Lung Non-Squamous Non-Small Cell Carcinoma' and 'Unresectable Lung Non-Small Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162641</classIRI>
<classLabel>Indium In 111-Autologous CMV-pp65-LAMP mRNA Loaded Dendritic Cells</classLabel>
<newAxiom>'Indium In 111-Autologous CMV-pp65-LAMP mRNA Loaded Dendritic Cells' SubClassOf 'Radioimmunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162640</classIRI>
<classLabel>Paraneoplastic Antibody</classLabel>
<newAxiom>'Paraneoplastic Antibody' SubClassOf 'Autoantibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162646</classIRI>
<classLabel>7 Tesla Magnetic Resonance Imaging</classLabel>
<newAxiom>'7 Tesla Magnetic Resonance Imaging' SubClassOf 'Magnetic Resonance Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162645</classIRI>
<classLabel>Pegylated Recombinant Interleukin-2 THOR-707</classLabel>
<newAxiom>'Pegylated Recombinant Interleukin-2 THOR-707' SubClassOf 'Recombinant Interleukin-2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162644</classIRI>
<classLabel>MR Fingerprinting</classLabel>
<newAxiom>'MR Fingerprinting' SubClassOf 'Magnetic Resonance Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162649</classIRI>
<classLabel>Engineered Toxin Body Targeting HER2 MT-5111</classLabel>
<newAxiom>'Engineered Toxin Body Targeting HER2 MT-5111' SubClassOf 'Immunotoxin'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162648</classIRI>
<classLabel>Advanced Breast Carcinoma</classLabel>
<newAxiom>'Advanced Breast Carcinoma' EquivalentTo 'Advanced Carcinoma' and 'Metastatic Breast Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162647</classIRI>
<classLabel>Behavioral Activation Intervention to Smoking Cessation and to Post-Cessation Weight Gain</classLabel>
<newAxiom>'Behavioral Activation Intervention to Smoking Cessation and to Post-Cessation Weight Gain' SubClassOf 'Smoking Cessation Intervention'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162653</classIRI>
<classLabel>Advanced Squamous Cell Carcinoma</classLabel>
<newAxiom>'Advanced Squamous Cell Carcinoma' EquivalentTo 'Advanced Carcinoma' and 'Metastatic Squamous Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162652</classIRI>
<classLabel>Recurrent Squamous Cell Carcinoma</classLabel>
<newAxiom>'Recurrent Squamous Cell Carcinoma' EquivalentTo 'Squamous Cell Carcinoma' and 'Recurrent Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162651</classIRI>
<classLabel>Widespread Metastasis</classLabel>
<newAxiom>'Widespread Metastasis' SubClassOf 'Widespread Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162650</classIRI>
<classLabel>Localized Metastasis</classLabel>
<newAxiom>'Localized Metastasis' SubClassOf 'Localized Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162657</classIRI>
<classLabel>ISUP Grade Pattern 4</classLabel>
<newAxiom>'ISUP Grade Pattern 4' SubClassOf 'International Society of Urological Pathology Gleason Grade Group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162656</classIRI>
<classLabel>ISUP Grade Pattern 3</classLabel>
<newAxiom>'ISUP Grade Pattern 3' SubClassOf 'International Society of Urological Pathology Gleason Grade Group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162655</classIRI>
<classLabel>ISUP Grade Pattern 2</classLabel>
<newAxiom>'ISUP Grade Pattern 2' SubClassOf 'International Society of Urological Pathology Gleason Grade Group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162654</classIRI>
<classLabel>ISUP Grade Pattern 1</classLabel>
<newAxiom>'ISUP Grade Pattern 1' SubClassOf 'International Society of Urological Pathology Gleason Grade Group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162658</classIRI>
<classLabel>ISUP Grade Pattern 5</classLabel>
<newAxiom>'ISUP Grade Pattern 5' SubClassOf 'International Society of Urological Pathology Gleason Grade Group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162629</classIRI>
<classLabel>Sacubitril/Valsartan</classLabel>
<newAxiom>'Sacubitril/Valsartan' SubClassOf 'Antihypertensive Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162620</classIRI>
<classLabel>Autologous Anti-CD19/CD22 CAR T-cells AUTO3</classLabel>
<newAxiom>'Autologous Anti-CD19/CD22 CAR T-cells AUTO3' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous Anti-CD19/CD22 CAR T-cells AUTO3' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous Anti-CD19/CD22 CAR T-cells AUTO3' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162624</classIRI>
<classLabel>Patient-derived WT1/PRAME/Survivin-specific Cytotoxic T-lymphocytes</classLabel>
<newAxiom>'Patient-derived WT1/PRAME/Survivin-specific Cytotoxic T-lymphocytes' SubClassOf 'Genetically-engineered Immune Cell'</newAxiom>
<newAxiom>'Patient-derived WT1/PRAME/Survivin-specific Cytotoxic T-lymphocytes' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Patient-derived WT1/PRAME/Survivin-specific Cytotoxic T-lymphocytes' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162623</classIRI>
<classLabel>Normal Tissue Segment</classLabel>
<newAxiom>'Normal Tissue Segment' SubClassOf 'Tissue Sample'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162622</classIRI>
<classLabel>Tumor Segment</classLabel>
<newAxiom>'Tumor Segment' SubClassOf 'Tumor Tissue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162621</classIRI>
<classLabel>QC Slide Review</classLabel>
<newAxiom>'QC Slide Review' SubClassOf 'Review'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162628</classIRI>
<classLabel>Whole Abdominopelvic Intensity-Modulated Radiotherapy</classLabel>
<newAxiom>'Whole Abdominopelvic Intensity-Modulated Radiotherapy' SubClassOf 'Intensity-Modulated Radiation Therapy'</newAxiom>
<newAxiom>'Whole Abdominopelvic Intensity-Modulated Radiotherapy' SubClassOf 'Extensive Radiation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162627</classIRI>
<classLabel>Autologous LMP1/LMP2/EBNA1-specific HLA-A02:01/24:02/11:01-restricted TCR-expressing T-lymphocytes YT-E001</classLabel>
<newAxiom>'Autologous LMP1/LMP2/EBNA1-specific HLA-A02:01/24:02/11:01-restricted TCR-expressing T-lymphocytes YT-E001' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous LMP1/LMP2/EBNA1-specific HLA-A02:01/24:02/11:01-restricted TCR-expressing T-lymphocytes YT-E001' SubClassOf 'T-cell Receptor-engineered T-cells'</newAxiom>
<newAxiom>'Autologous LMP1/LMP2/EBNA1-specific HLA-A02:01/24:02/11:01-restricted TCR-expressing T-lymphocytes YT-E001' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162626</classIRI>
<classLabel>Autologous Anti-gp100CAR-CD3zeta-4-1BB-IL-15-PD1-expressing Tri-functional T-lymphocytes</classLabel>
<newAxiom>'Autologous Anti-gp100CAR-CD3zeta-4-1BB-IL-15-PD1-expressing Tri-functional T-lymphocytes' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous Anti-gp100CAR-CD3zeta-4-1BB-IL-15-PD1-expressing Tri-functional T-lymphocytes' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous Anti-gp100CAR-CD3zeta-4-1BB-IL-15-PD1-expressing Tri-functional T-lymphocytes' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162625</classIRI>
<classLabel>Anti-TIM-3 Monoclonal Antibody INCAGN02390</classLabel>
<newAxiom>'Anti-TIM-3 Monoclonal Antibody INCAGN02390' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
<newAxiom>'Anti-TIM-3 Monoclonal Antibody INCAGN02390' SubClassOf 'Anti-TIM-3 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162631</classIRI>
<classLabel>HOXB1 wt Allele</classLabel>
<newAxiom>'HOXB1 wt Allele' SubClassOf 'HOXB1 Gene'</newAxiom>
<newAxiom>'HOXB1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '17q21.32'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162630</classIRI>
<classLabel>HOXB1 Gene</classLabel>
<newAxiom>'HOXB1 Gene' SubClassOf 'HOXB Gene Family'</newAxiom>
<newAxiom>'HOXB1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Pattern Formation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162635</classIRI>
<classLabel>Oncolytic HSV-1 C134</classLabel>
<newAxiom>'Oncolytic HSV-1 C134' SubClassOf 'Oncolytic Virus'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162634</classIRI>
<classLabel>Adenoviral Vector Encoding VEGF-C LX-1101</classLabel>
<newAxiom>'Adenoviral Vector Encoding VEGF-C LX-1101' SubClassOf 'Gene Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162633</classIRI>
<classLabel>Personalized Neoantigen Peptide Vaccine iNeo-Vac-P01</classLabel>
<newAxiom>'Personalized Neoantigen Peptide Vaccine iNeo-Vac-P01' SubClassOf 'Peptide Vaccine'</newAxiom>
<newAxiom>'Personalized Neoantigen Peptide Vaccine iNeo-Vac-P01' SubClassOf 'Antineoplastic Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162632</classIRI>
<classLabel>Homeobox Protein Hox-B1</classLabel>
<newAxiom>'Homeobox Protein Hox-B1' EquivalentTo 'Transcription Factor' and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleus') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Homeo Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Sequence-Specific DNA Binding Protein') and ('Gene_Product_Has_Biochemical_Function' some 'Homeobox Family Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Regulation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Pattern Formation') and ('Gene_Product_Encoded_By_Gene' some 'HOXB1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162639</classIRI>
<classLabel>Paraneoplastic Antibody Positive</classLabel>
<newAxiom>'Paraneoplastic Antibody Positive' SubClassOf 'Positive Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162638</classIRI>
<classLabel>Non-Metastatic Prostate Carcinoma</classLabel>
<newAxiom>'Non-Metastatic Prostate Carcinoma' EquivalentTo 'Prostate Carcinoma' and 'Non-Metastatic Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162637</classIRI>
<classLabel>Chimeric Costimulatory Converting Receptor-modified NK-92 Cells</classLabel>
<newAxiom>'Chimeric Costimulatory Converting Receptor-modified NK-92 Cells' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162636</classIRI>
<classLabel>Anti-PD-1 Monoclonal Antibody F520</classLabel>
<newAxiom>'Anti-PD-1 Monoclonal Antibody F520' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-PD-1 Monoclonal Antibody F520' SubClassOf 'Anti-PD1 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162609</classIRI>
<classLabel>Clinical Regional Lymph Nodes TNM Finding</classLabel>
<newAxiom>'Clinical Regional Lymph Nodes TNM Finding' SubClassOf 'Clinical TNM Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162608</classIRI>
<classLabel>Navigated Transcranial Magnetic Stimulation</classLabel>
<newAxiom>'Navigated Transcranial Magnetic Stimulation' SubClassOf 'Transcranial Magnetic Stimulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162607</classIRI>
<classLabel>Tumor Infiltrating Lymphocyte is Present</classLabel>
<newAxiom>'Tumor Infiltrating Lymphocyte is Present' SubClassOf 'CPTAC Responses'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162602</classIRI>
<classLabel>Unresectable Fibrolamellar Carcinoma</classLabel>
<newAxiom>'Unresectable Fibrolamellar Carcinoma' EquivalentTo 'Unresectable Hepatocellular Carcinoma' and 'Fibrolamellar Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162601</classIRI>
<classLabel>Bone Marrow Differential Count within 24 Hours of Banking</classLabel>
<newAxiom>'Bone Marrow Differential Count within 24 Hours of Banking' SubClassOf 'Form Directive'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162600</classIRI>
<classLabel>Unresectable Colorectal Carcinoma</classLabel>
<newAxiom>'Unresectable Colorectal Carcinoma' EquivalentTo 'Unresectable Digestive System Carcinoma' and 'Colorectal Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162606</classIRI>
<classLabel>Tumor Cell Necrosis is Present</classLabel>
<newAxiom>'Tumor Cell Necrosis is Present' SubClassOf 'CPTAC Responses'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162605</classIRI>
<classLabel>Lymphatic Invasion is Present</classLabel>
<newAxiom>'Lymphatic Invasion is Present' SubClassOf 'CPTAC Responses'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162604</classIRI>
<classLabel>Paraneoplastic Syndrome is Present</classLabel>
<newAxiom>'Paraneoplastic Syndrome is Present' SubClassOf 'CPTAC Responses'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162603</classIRI>
<classLabel>Additional Surgery for New Tumor Event Not Evaluated</classLabel>
<newAxiom>'Additional Surgery for New Tumor Event Not Evaluated' SubClassOf 'CPTAC Responses'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162619</classIRI>
<classLabel>Locally Advanced Urethral Urothelial Carcinoma</classLabel>
<newAxiom>'Locally Advanced Urethral Urothelial Carcinoma' EquivalentTo 'Metastatic Urethral Urothelial Carcinoma' and 'Locally Advanced Urothelial Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162618</classIRI>
<classLabel>Locally Advanced Bladder Urothelial Carcinoma</classLabel>
<newAxiom>'Locally Advanced Bladder Urothelial Carcinoma' EquivalentTo 'Metastatic Bladder Urothelial Carcinoma' and 'Locally Advanced Urothelial Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162613</classIRI>
<classLabel>Hand Function Test</classLabel>
<newAxiom>'Hand Function Test' SubClassOf 'Diagnostic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162612</classIRI>
<classLabel>Recurrent Adamantinomatous Craniopharyngioma</classLabel>
<newAxiom>'Recurrent Adamantinomatous Craniopharyngioma' EquivalentTo 'Recurrent Craniopharyngioma' and 'Adamantinomatous Craniopharyngioma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162611</classIRI>
<classLabel>Warm Antibody Autoimmune Hemolytic Anemia</classLabel>
<newAxiom>'Warm Antibody Autoimmune Hemolytic Anemia' SubClassOf 'Autoimmune Hemolytic Anemia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162610</classIRI>
<classLabel>Clinical Distant Metastasis TNM Finding</classLabel>
<newAxiom>'Clinical Distant Metastasis TNM Finding' SubClassOf 'Clinical TNM Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162617</classIRI>
<classLabel>Locally Advanced Renal Pelvis Urothelial Carcinoma</classLabel>
<newAxiom>'Locally Advanced Renal Pelvis Urothelial Carcinoma' EquivalentTo 'Metastatic Renal Pelvis Urothelial Carcinoma' and 'Locally Advanced Urothelial Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162616</classIRI>
<classLabel>Locally Advanced Ureter Urothelial Carcinoma</classLabel>
<newAxiom>'Locally Advanced Ureter Urothelial Carcinoma' EquivalentTo 'Metastatic Ureter Urothelial Carcinoma' and 'Locally Advanced Urothelial Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162615</classIRI>
<classLabel>Tumor Laterality Unknown</classLabel>
<newAxiom>'Tumor Laterality Unknown' SubClassOf 'CPTAC Responses'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162614</classIRI>
<classLabel>Tumor Laterality Midline</classLabel>
<newAxiom>'Tumor Laterality Midline' SubClassOf 'CPTAC Responses'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162392</classIRI>
<classLabel>KLF3 Gene</classLabel>
<newAxiom>'KLF3 Gene' SubClassOf 'Transcription Factor Gene'</newAxiom>
<newAxiom>'KLF3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Activation'</newAxiom>
<newAxiom>'KLF3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Erythropoiesis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162391</classIRI>
<classLabel>Krueppel-Like Factor 2</classLabel>
<newAxiom>'Krueppel-Like Factor 2' EquivalentTo 'Transcription Factor' and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'C2H2 Zinc Finger') and ('Gene_Product_Has_Biochemical_Function' some 'Sequence-Specific DNA Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Binding') and ('Gene_Product_Encoded_By_Gene' some 'KLF2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162390</classIRI>
<classLabel>KLF2 wt Allele</classLabel>
<newAxiom>'KLF2 wt Allele' SubClassOf 'KLF2 Gene'</newAxiom>
<newAxiom>'KLF2 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '19p13.11'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162385</classIRI>
<classLabel>MIR30C2 wt Allele</classLabel>
<newAxiom>'MIR30C2 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '6q13'</newAxiom>
<newAxiom>'MIR30C2 wt Allele' SubClassOf 'MIR30C2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162384</classIRI>
<classLabel>MIR30C1 wt Allele</classLabel>
<newAxiom>'MIR30C1 wt Allele' SubClassOf 'MIR30C1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162383</classIRI>
<classLabel>MIR30C2 Gene</classLabel>
<newAxiom>'MIR30C2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Angiogenic Process'</newAxiom>
<newAxiom>'MIR30C2 Gene' SubClassOf 'MicroRNA Gene'</newAxiom>
<newAxiom>'MIR30C2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Wound Repair'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162382</classIRI>
<classLabel>MIR30C1 Gene</classLabel>
<newAxiom>'MIR30C1 Gene' SubClassOf 'MicroRNA Gene'</newAxiom>
<newAxiom>'MIR30C1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Wound Repair'</newAxiom>
<newAxiom>'MIR30C1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Angiogenic Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162389</classIRI>
<classLabel>KLF2 Gene</classLabel>
<newAxiom>'KLF2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Activation'</newAxiom>
<newAxiom>'KLF2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'DNA Binding'</newAxiom>
<newAxiom>'KLF2 Gene' SubClassOf 'Transcription Factor Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162388</classIRI>
<classLabel>MicroRNA 30c</classLabel>
<newAxiom>'MicroRNA 30c' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Angiogenic Process'</newAxiom>
<newAxiom>'MicroRNA 30c' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'MIR30C2 Gene'</newAxiom>
<newAxiom>'MicroRNA 30c' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Wound Repair'</newAxiom>
<newAxiom>'MicroRNA 30c' SubClassOf 'MicroRNA'</newAxiom>
<newAxiom>'MicroRNA 30c' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'MIR30C1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162387</classIRI>
<classLabel>MIR30C2 Pre-miRNA</classLabel>
<newAxiom>'MIR30C2 Pre-miRNA' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Angiogenic Process'</newAxiom>
<newAxiom>'MIR30C2 Pre-miRNA' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'MIR30C2 Gene'</newAxiom>
<newAxiom>'MIR30C2 Pre-miRNA' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Wound Repair'</newAxiom>
<newAxiom>'MIR30C2 Pre-miRNA' SubClassOf 'Pre-miRNA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162386</classIRI>
<classLabel>MIR30C1 Pre-miRNA</classLabel>
<newAxiom>'MIR30C1 Pre-miRNA' SubClassOf 'Pre-miRNA'</newAxiom>
<newAxiom>'MIR30C1 Pre-miRNA' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Wound Repair'</newAxiom>
<newAxiom>'MIR30C1 Pre-miRNA' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'MIR30C1 Gene'</newAxiom>
<newAxiom>'MIR30C1 Pre-miRNA' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Angiogenic Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162396</classIRI>
<classLabel>TP53 NP_000537.3:p.R181H</classLabel>
<newAxiom>'TP53 NP_000537.3:p.R181H' SubClassOf 'TP53 Protein Variant'</newAxiom>
<newAxiom>'TP53 NP_000537.3:p.R181H' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'TP53 NM_000546.5:c.542GA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162395</classIRI>
<classLabel>TP53 NM_000546.5:c.542GA</classLabel>
<newAxiom>'TP53 NM_000546.5:c.542GA' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'TP53 NP_000537.3:p.R181H'</newAxiom>
<newAxiom>'TP53 NM_000546.5:c.542GA' SubClassOf 'TP53 Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162394</classIRI>
<classLabel>Krueppel-Like Factor 3</classLabel>
<newAxiom>'Krueppel-Like Factor 3' EquivalentTo 'Transcription Factor' and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'C2H2 Zinc Finger') and ('Gene_Product_Has_Biochemical_Function' some 'Sequence-Specific DNA Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Erythropoiesis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Binding') and ('Gene_Product_Encoded_By_Gene' some 'KLF3 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162393</classIRI>
<classLabel>KLF3 wt Allele</classLabel>
<newAxiom>'KLF3 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '4p14'</newAxiom>
<newAxiom>'KLF3 wt Allele' SubClassOf 'KLF3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162399</classIRI>
<classLabel>Cone-Rod Dystrophy 2</classLabel>
<newAxiom>'Cone-Rod Dystrophy 2' SubClassOf 'Hereditary Retinal Dystrophy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162398</classIRI>
<classLabel>Glycogen Storage Disease Type Ia</classLabel>
<newAxiom>'Glycogen Storage Disease Type Ia' SubClassOf 'Glycogen Storage Disease Type I'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162370</classIRI>
<classLabel>CASS4 wt Allele</classLabel>
<newAxiom>'CASS4 wt Allele' SubClassOf 'CASS4 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162363</classIRI>
<classLabel>SLC24A4 wt Allele</classLabel>
<newAxiom>'SLC24A4 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Olfactory Transduction Pathway'</newAxiom>
<newAxiom>'SLC24A4 wt Allele' SubClassOf 'SLC24A4 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162362</classIRI>
<classLabel>SLC24A4 Gene</classLabel>
<newAxiom>'SLC24A4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Ion Transport Process'</newAxiom>
<newAxiom>'SLC24A4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transmembrane Transport'</newAxiom>
<newAxiom>'SLC24A4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Olfaction'</newAxiom>
<newAxiom>'SLC24A4 Gene' SubClassOf 'Transport Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162361</classIRI>
<classLabel>Enoyl-CoA Hydratase Domain-Containing Protein 3, Mitochondrial</classLabel>
<newAxiom>'Enoyl-CoA Hydratase Domain-Containing Protein 3, Mitochondrial' SubClassOf 'Isomerase'</newAxiom>
<newAxiom>'Enoyl-CoA Hydratase Domain-Containing Protein 3, Mitochondrial' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Mitochondrion'</newAxiom>
<newAxiom>'Enoyl-CoA Hydratase Domain-Containing Protein 3, Mitochondrial' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'ECHDC3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162360</classIRI>
<classLabel>ECHDC3 wt Allele</classLabel>
<newAxiom>'ECHDC3 wt Allele' SubClassOf 'ECHDC3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162367</classIRI>
<classLabel>Phospholipid-Transporting ATPase ABCA7</classLabel>
<newAxiom>'Phospholipid-Transporting ATPase ABCA7' EquivalentTo 'Translocase' and 'ABC Transporter' and ('Gene_Product_Is_Element_In_Pathway' some 'ABC Transporter Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Endosome') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Golgi Apparatus') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Rough Endoplasmic Reticulum') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Smooth Endoplasmic Reticulum') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transmembrane Transport') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Lipid Transport') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Phagocytosis') and ('Gene_Product_Encoded_By_Gene' some 'ABCA7 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162366</classIRI>
<classLabel>ABCA7 wt Allele</classLabel>
<newAxiom>'ABCA7 wt Allele' EquivalentTo 'ABCA7 Gene' and ('Gene_Is_Element_In_Pathway' some 'ABC Transporter Pathway') and ('Gene_In_Chromosomal_Location' some '19p13.3')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162365</classIRI>
<classLabel>ABCA7 Gene</classLabel>
<newAxiom>'ABCA7 Gene' SubClassOf 'Translocase Gene'</newAxiom>
<newAxiom>'ABCA7 Gene' SubClassOf 'Transport Protein Gene'</newAxiom>
<newAxiom>'ABCA7 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Lipid Transport'</newAxiom>
<newAxiom>'ABCA7 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transmembrane Transport'</newAxiom>
<newAxiom>'ABCA7 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Phagocytosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162364</classIRI>
<classLabel>Sodium/Potassium/Calcium Exchanger 4</classLabel>
<newAxiom>'Sodium/Potassium/Calcium Exchanger 4' EquivalentTo 'Transport Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Olfactory Transduction Pathway') and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Solute Carrier Family') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Olfaction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transmembrane Transport') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Ion Transport Process') and ('Gene_Product_Encoded_By_Gene' some 'SLC24A4 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162369</classIRI>
<classLabel>CASS4 Gene</classLabel>
<newAxiom>'CASS4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell Motility'</newAxiom>
<newAxiom>'CASS4 Gene' SubClassOf 'Adaptor Signaling Protein Gene'</newAxiom>
<newAxiom>'CASS4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell Adhesion Process'</newAxiom>
<newAxiom>'CASS4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cytoskeletal Modeling'</newAxiom>
<newAxiom>'CASS4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Signal Transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162368</classIRI>
<classLabel>Fagotti Score</classLabel>
<newAxiom>'Fagotti Score' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162381</classIRI>
<classLabel>Methylcytosine Dioxygenase TET3</classLabel>
<newAxiom>'Methylcytosine Dioxygenase TET3' EquivalentTo 'Oxidoreductase' and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Zinc-Binding, DNA-Binding Motif') and ('Gene_Product_Has_Biochemical_Function' some 'Chromatin Remodeling Factor') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Nucleotide Metabolic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Chromatin Remodeling') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Methylation Regulation') and ('Gene_Product_Encoded_By_Gene' some 'TET3 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162380</classIRI>
<classLabel>TET3 wt Allele</classLabel>
<newAxiom>'TET3 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '2p13.1'</newAxiom>
<newAxiom>'TET3 wt Allele' SubClassOf 'TET3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162374</classIRI>
<classLabel>Grainyhead-Like Protein 2 Homolog</classLabel>
<newAxiom>'Grainyhead-Like Protein 2 Homolog' EquivalentTo 'Transcription Factor' and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleus') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transcriptional Activation Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Sequence-Specific DNA Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Embryogenesis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Morphogenesis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Organogenesis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Histogenic Process') and ('Gene_Product_Encoded_By_Gene' some 'GRHL2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162373</classIRI>
<classLabel>GRHL2 wt Allele</classLabel>
<newAxiom>'GRHL2 wt Allele' SubClassOf 'GRHL2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162372</classIRI>
<classLabel>GRHL2 Gene</classLabel>
<newAxiom>'GRHL2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Organogenesis'</newAxiom>
<newAxiom>'GRHL2 Gene' SubClassOf 'Transcription Factor Gene'</newAxiom>
<newAxiom>'GRHL2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Embryogenesis'</newAxiom>
<newAxiom>'GRHL2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Histogenic Process'</newAxiom>
<newAxiom>'GRHL2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Morphogenesis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162371</classIRI>
<classLabel>Cas Scaffolding Protein Family Member 4</classLabel>
<newAxiom>'Cas Scaffolding Protein Family Member 4' EquivalentTo 'Adaptor Signaling Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoskeleton') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'SH3 Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Proline-Rich Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Scaffolding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Motility') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Signal Transduction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cytoskeletal Modeling') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Adhesion Process') and ('Gene_Product_Encoded_By_Gene' some 'CASS4 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162378</classIRI>
<classLabel>C-Type Lectin Domain Family 12 Member A</classLabel>
<newAxiom>'C-Type Lectin Domain Family 12 Member A' EquivalentTo 'Receptor' and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Expressed_In_Tissue' some 'Myeloid Cell') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'ITIM') and ('Gene_Product_Has_Biochemical_Function' some 'Lectin') and ('Gene_Product_Has_Biochemical_Function' some 'Cell Surface Receptor') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cellular Secretion') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Signal Transduction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Receptor Signaling') and ('Gene_Product_Encoded_By_Gene' some 'CLEC12A Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162377</classIRI>
<classLabel>CLEC12A wt Allele</classLabel>
<newAxiom>'CLEC12A wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '12p13.31'</newAxiom>
<newAxiom>'CLEC12A wt Allele' SubClassOf 'CLEC12A Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162376</classIRI>
<classLabel>CLEC12A Gene</classLabel>
<newAxiom>'CLEC12A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Receptor Signaling'</newAxiom>
<newAxiom>'CLEC12A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cellular Secretion'</newAxiom>
<newAxiom>'CLEC12A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Signal Transduction'</newAxiom>
<newAxiom>'CLEC12A Gene' SubClassOf 'Receptor Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162375</classIRI>
<classLabel>PLK1 Inhibitor CYC140</classLabel>
<newAxiom>'PLK1 Inhibitor CYC140' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'PLK1 Inhibitor CYC140' SubClassOf 'Serine/Threonine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162379</classIRI>
<classLabel>TET3 Gene</classLabel>
<newAxiom>'TET3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Nucleotide Metabolic Process'</newAxiom>
<newAxiom>'TET3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'DNA Methylation Regulation'</newAxiom>
<newAxiom>'TET3 Gene' SubClassOf 'Oxidoreductase Gene'</newAxiom>
<newAxiom>'TET3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Chromatin Remodeling'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162341</classIRI>
<classLabel>Berbamine</classLabel>
<newAxiom>'Berbamine' SubClassOf 'Signal Transduction Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162340</classIRI>
<classLabel>Berbamine Dihydrochloride</classLabel>
<newAxiom>'Berbamine Dihydrochloride' SubClassOf 'Signal Transduction Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162345</classIRI>
<classLabel>TRPM8 Agonist D-3263</classLabel>
<newAxiom>'TRPM8 Agonist D-3263' SubClassOf 'Antineoplastic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162344</classIRI>
<classLabel>Combretastatin A-1</classLabel>
<newAxiom>'Combretastatin A-1' SubClassOf 'Colchicine-Site Binding Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162343</classIRI>
<classLabel>Vascular Disrupting Agent BNC105</classLabel>
<newAxiom>'Vascular Disrupting Agent BNC105' SubClassOf 'Tubulin Binding Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162342</classIRI>
<classLabel>FGFR4 Inhibitor BLU 9931</classLabel>
<newAxiom>'FGFR4 Inhibitor BLU 9931' SubClassOf 'FGFR Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162349</classIRI>
<classLabel>Ophthalmic Examinations Normal or Reference Range Indicator</classLabel>
<newAxiom>'Ophthalmic Examinations Normal or Reference Range Indicator' SubClassOf 'Normal Range Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162348</classIRI>
<classLabel>Exatecan Mesylate Anhydrous</classLabel>
<newAxiom>'Exatecan Mesylate Anhydrous' SubClassOf 'Camptothecin Analogue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162347</classIRI>
<classLabel>Detumomab</classLabel>
<newAxiom>'Detumomab' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162346</classIRI>
<classLabel>Dactolisib Tosylate</classLabel>
<newAxiom>'Dactolisib Tosylate' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'Dactolisib Tosylate' SubClassOf 'Phosphatidylinositide 3-Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162352</classIRI>
<classLabel>Urinary System Findings Specimen Type</classLabel>
<newAxiom>'Urinary System Findings Specimen Type' SubClassOf 'Biospecimen Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162351</classIRI>
<classLabel>Microbiology Susceptibility Specimen Type</classLabel>
<newAxiom>'Microbiology Susceptibility Specimen Type' SubClassOf 'Biospecimen Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162350</classIRI>
<classLabel>Microbiology Susceptibility Normal or Reference Range Indicator</classLabel>
<newAxiom>'Microbiology Susceptibility Normal or Reference Range Indicator' SubClassOf 'Normal Range Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162356</classIRI>
<classLabel>IQCK Gene</classLabel>
<newAxiom>'IQCK Gene' SubClassOf 'Ligand Binding Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162355</classIRI>
<classLabel>Dexamethasone/Selinexor Regimen</classLabel>
<newAxiom>'Dexamethasone/Selinexor Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Dexamethasone Sodium Phosphate'</newAxiom>
<newAxiom>'Dexamethasone/Selinexor Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Pomalidomide'</newAxiom>
<newAxiom>'Dexamethasone/Selinexor Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Elotuzumab'</newAxiom>
<newAxiom>'Dexamethasone/Selinexor Regimen' SubClassOf 'Regimen Used to Treat Plasma Cell Myeloma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162354</classIRI>
<classLabel>Microbiology Susceptibility Agent Concentration Unit</classLabel>
<newAxiom>'Microbiology Susceptibility Agent Concentration Unit' SubClassOf 'Miscellaneous Concentration Unit'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162353</classIRI>
<classLabel>Procedure Agent Yes No Indicator</classLabel>
<newAxiom>'Procedure Agent Yes No Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162359</classIRI>
<classLabel>ECHDC3 Gene</classLabel>
<newAxiom>'ECHDC3 Gene' SubClassOf 'Isomerase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162358</classIRI>
<classLabel>IQ Domain-Containing Protein K</classLabel>
<newAxiom>'IQ Domain-Containing Protein K' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'IQCK Gene'</newAxiom>
<newAxiom>'IQ Domain-Containing Protein K' SubClassOf 'Ligand Binding Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162357</classIRI>
<classLabel>IQCK wt Allele</classLabel>
<newAxiom>'IQCK wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '16p12.3'</newAxiom>
<newAxiom>'IQCK wt Allele' SubClassOf 'IQCK Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162323</classIRI>
<classLabel>Healthcare Encounter Previous Occurrence</classLabel>
<newAxiom>'Healthcare Encounter Previous Occurrence' SubClassOf 'Event Occurrence Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162322</classIRI>
<classLabel>Functional Tests Previous Occurrence</classLabel>
<newAxiom>'Functional Tests Previous Occurrence' SubClassOf 'Event Occurrence Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162321</classIRI>
<classLabel>Disease Response or Clinical Classification Previous Occurrence</classLabel>
<newAxiom>'Disease Response or Clinical Classification Previous Occurrence' SubClassOf 'Event Occurrence Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162320</classIRI>
<classLabel>Clinical Event Previous Occurrence</classLabel>
<newAxiom>'Clinical Event Previous Occurrence' SubClassOf 'Event Occurrence Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162327</classIRI>
<classLabel>Disease Response or Clinical Classification Ongoing</classLabel>
<newAxiom>'Disease Response or Clinical Classification Ongoing' SubClassOf 'Event Occurrence Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162326</classIRI>
<classLabel>Substance Use Previous Occurrence</classLabel>
<newAxiom>'Substance Use Previous Occurrence' SubClassOf 'Event Occurrence Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162325</classIRI>
<classLabel>Agent Previous Occurrence</classLabel>
<newAxiom>'Agent Previous Occurrence' SubClassOf 'Event Occurrence Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162324</classIRI>
<classLabel>Microbiology Susceptibility Previous Occurrence</classLabel>
<newAxiom>'Microbiology Susceptibility Previous Occurrence' SubClassOf 'Event Occurrence Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162329</classIRI>
<classLabel>Ongoing Procedure Agents</classLabel>
<newAxiom>'Ongoing Procedure Agents' SubClassOf 'Event Occurrence Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162328</classIRI>
<classLabel>Ongoing Microbiology Susceptibility</classLabel>
<newAxiom>'Ongoing Microbiology Susceptibility' SubClassOf 'Event Occurrence Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162330</classIRI>
<classLabel>Ongoing Substance Use</classLabel>
<newAxiom>'Ongoing Substance Use' SubClassOf 'Event Occurrence Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162334</classIRI>
<classLabel>Nervous System Findings Completion Status</classLabel>
<newAxiom>'Nervous System Findings Completion Status' SubClassOf 'Completion Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162333</classIRI>
<classLabel>Musculoskeletal Findings, Connective and Soft Tissue Findings Completion Status</classLabel>
<newAxiom>'Musculoskeletal Findings, Connective and Soft Tissue Findings Completion Status' SubClassOf 'Completion Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162332</classIRI>
<classLabel>Meal Data Completion Status</classLabel>
<newAxiom>'Meal Data Completion Status' SubClassOf 'Completion Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162331</classIRI>
<classLabel>Functional Tests Completion Status</classLabel>
<newAxiom>'Functional Tests Completion Status' SubClassOf 'Completion Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162338</classIRI>
<classLabel>Urinary System Findings Completion Status</classLabel>
<newAxiom>'Urinary System Findings Completion Status' SubClassOf 'Completion Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162337</classIRI>
<classLabel>Substance Use Completion Status</classLabel>
<newAxiom>'Substance Use Completion Status' SubClassOf 'Completion Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162336</classIRI>
<classLabel>Procedure Agents Completion Status</classLabel>
<newAxiom>'Procedure Agents Completion Status' SubClassOf 'Completion Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162335</classIRI>
<classLabel>Ophthalmic Examinations Completion Status</classLabel>
<newAxiom>'Ophthalmic Examinations Completion Status' SubClassOf 'Completion Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162339</classIRI>
<classLabel>Src Kinase Inhibitor M475271</classLabel>
<newAxiom>'Src Kinase Inhibitor M475271' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'Src Kinase Inhibitor M475271' SubClassOf 'Tyrosine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162301</classIRI>
<classLabel>MET NP_000236.2:p.V504L</classLabel>
<newAxiom>'MET NP_000236.2:p.V504L' SubClassOf 'MET Protein Variant'</newAxiom>
<newAxiom>'MET NP_000236.2:p.V504L' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MET NM_000245.3:c.1510GC'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162300</classIRI>
<classLabel>MET NM_000245.3:c.1510GC</classLabel>
<newAxiom>'MET NM_000245.3:c.1510GC' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'MET NP_000236.2:p.V504L'</newAxiom>
<newAxiom>'MET NM_000245.3:c.1510GC' SubClassOf 'MET Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162305</classIRI>
<classLabel>EBV-Related Sarcoma</classLabel>
<newAxiom>'EBV-Related Sarcoma' EquivalentTo 'EBV-Related Malignant Neoplasm' and 'Sarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162304</classIRI>
<classLabel>EBV-Related Gastric Carcinoma</classLabel>
<newAxiom>'EBV-Related Gastric Carcinoma' EquivalentTo 'EBV-Related Carcinoma' and 'Gastric Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162303</classIRI>
<classLabel>MET NP_000236.2:p.I639L</classLabel>
<newAxiom>'MET NP_000236.2:p.I639L' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MET NM_000245.3:c.1915AC'</newAxiom>
<newAxiom>'MET NP_000236.2:p.I639L' SubClassOf 'MET Protein Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162302</classIRI>
<classLabel>MET NM_000245.3:c.1915AC</classLabel>
<newAxiom>'MET NM_000245.3:c.1915AC' SubClassOf 'MET Gene Mutation'</newAxiom>
<newAxiom>'MET NM_000245.3:c.1915AC' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'MET NP_000236.2:p.I639L'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162309</classIRI>
<classLabel>MSH6 Negative</classLabel>
<newAxiom>'MSH6 Negative' SubClassOf 'Negative Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162308</classIRI>
<classLabel>MSH2 Negative</classLabel>
<newAxiom>'MSH2 Negative' SubClassOf 'Negative Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162307</classIRI>
<classLabel>MLH1 Negative</classLabel>
<newAxiom>'MLH1 Negative' SubClassOf 'Negative Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162306</classIRI>
<classLabel>EBV-Related Leiomyosarcoma</classLabel>
<newAxiom>'EBV-Related Leiomyosarcoma' EquivalentTo 'EBV-Related Sarcoma' and 'Leiomyosarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162312</classIRI>
<classLabel>Urethral Ointment Dosage Form</classLabel>
<newAxiom>'Urethral Ointment Dosage Form' SubClassOf 'Ointment Dosage Form'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162311</classIRI>
<classLabel>Inosinic Acid</classLabel>
<newAxiom>'Inosinic Acid' SubClassOf 'Nucleotide'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162310</classIRI>
<classLabel>PMS2 Negative</classLabel>
<newAxiom>'PMS2 Negative' SubClassOf 'Negative Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162316</classIRI>
<classLabel>Proton Multiple Quantum Coherence Magnetic Resonance Spectroscopic Imaging</classLabel>
<newAxiom>'Proton Multiple Quantum Coherence Magnetic Resonance Spectroscopic Imaging' SubClassOf 'Magnetic Resonance Spectroscopic Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162315</classIRI>
<classLabel>Nasal Powder in Single-Dose Container</classLabel>
<newAxiom>'Nasal Powder in Single-Dose Container' SubClassOf 'Dosage Form and Package Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162314</classIRI>
<classLabel>Powder and Solution for Suspension for Injection</classLabel>
<newAxiom>'Powder and Solution for Suspension for Injection' SubClassOf 'Combined Dosage Form'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162313</classIRI>
<classLabel>Solution for Infusion in Cartridge</classLabel>
<newAxiom>'Solution for Infusion in Cartridge' SubClassOf 'Dosage Form and Package Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162319</classIRI>
<classLabel>Adverse Event Previous Occurrence</classLabel>
<newAxiom>'Adverse Event Previous Occurrence' SubClassOf 'Event Occurrence Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162318</classIRI>
<classLabel>Urinary System Findings Time Point Reference</classLabel>
<newAxiom>'Urinary System Findings Time Point Reference' SubClassOf 'Reference Time Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162317</classIRI>
<classLabel>Ophthalmic Examinations External File Path</classLabel>
<newAxiom>'Ophthalmic Examinations External File Path' SubClassOf 'Pathname'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162409</classIRI>
<classLabel>ASNS Gene</classLabel>
<newAxiom>'ASNS Gene' SubClassOf 'Ligase Gene'</newAxiom>
<newAxiom>'ASNS Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Amino Acid Biosynthesis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162400</classIRI>
<classLabel>KHDRBS3 Gene</classLabel>
<newAxiom>'KHDRBS3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Binding'</newAxiom>
<newAxiom>'KHDRBS3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Alternate Splicing'</newAxiom>
<newAxiom>'KHDRBS3 Gene' SubClassOf 'Ligand Binding Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162404</classIRI>
<classLabel>CREM wt Allele</classLabel>
<newAxiom>'CREM wt Allele' EquivalentTo 'CREM Gene' and ('Gene_Is_Element_In_Pathway' some 'Spermatogenesis Regulation Pathway') and ('Gene_Is_Element_In_Pathway' some 'Pain Repression Pathway') and ('Gene_Is_Element_In_Pathway' some 'Calcium Signaling in the CD4+ TCR Pathway') and ('Gene_In_Chromosomal_Location' some '10p11.21')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162403</classIRI>
<classLabel>CREM Gene</classLabel>
<newAxiom>'CREM Gene' SubClassOf 'CREB Family Gene'</newAxiom>
<newAxiom>'CREM Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'DNA Binding'</newAxiom>
<newAxiom>'CREM Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Regulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162402</classIRI>
<classLabel>KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 3</classLabel>
<newAxiom>'KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 3' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'KH Domain'</newAxiom>
<newAxiom>'KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 3' SubClassOf 'RNA Binding Protein'</newAxiom>
<newAxiom>'KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 3' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Nucleus'</newAxiom>
<newAxiom>'KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 3' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Binding'</newAxiom>
<newAxiom>'KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 3' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Alternate Splicing'</newAxiom>
<newAxiom>'KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 3' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'KHDRBS3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162401</classIRI>
<classLabel>KHDRBS3 wt Allele</classLabel>
<newAxiom>'KHDRBS3 wt Allele' SubClassOf 'KHDRBS3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162408</classIRI>
<classLabel>Tomoregulin-2</classLabel>
<newAxiom>'Tomoregulin-2' EquivalentTo 'Regulatory Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'EGF-Like Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Nerve Cell Survival') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Migration Inhibition Process') and ('Gene_Product_Encoded_By_Gene' some 'TMEFF2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162407</classIRI>
<classLabel>TMEFF2 wt Allele</classLabel>
<newAxiom>'TMEFF2 wt Allele' SubClassOf 'TMEFF2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162406</classIRI>
<classLabel>TMEFF2 Gene</classLabel>
<newAxiom>'TMEFF2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Nerve Cell Survival'</newAxiom>
<newAxiom>'TMEFF2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell Migration Inhibition Process'</newAxiom>
<newAxiom>'TMEFF2 Gene' SubClassOf 'Regulatory Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162405</classIRI>
<classLabel>cAMP-Responsive Element Modulator</classLabel>
<newAxiom>'cAMP-Responsive Element Modulator' EquivalentTo 'cAMP Responsive Element Binding Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Spermatogenesis Regulation Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Pain Repression Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Calcium Signaling in the CD4+ TCR Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Spermatid') and ('Gene_Product_Expressed_In_Tissue' some 'Testis') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'bZIP Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Regulation') and ('Gene_Product_Encoded_By_Gene' some 'CREM Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162411</classIRI>
<classLabel>Asparagine Synthetase [Glutamine-Hydrolyzing]</classLabel>
<newAxiom>'Asparagine Synthetase [Glutamine-Hydrolyzing]' EquivalentTo 'Ligase' and ('Gene_Product_Is_Element_In_Pathway' some 'Nitrogen Metabolism Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Alanine, Aspartate and Glutamate Metabolism Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytosol') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Amino Acid Biosynthesis') and ('Gene_Product_Encoded_By_Gene' some 'ASNS Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162410</classIRI>
<classLabel>ASNS wt Allele</classLabel>
<newAxiom>'ASNS wt Allele' EquivalentTo 'ASNS Gene' and ('Gene_Is_Element_In_Pathway' some 'Nitrogen Metabolism Pathway') and ('Gene_Is_Element_In_Pathway' some 'Alanine, Aspartate and Glutamate Metabolism Pathway') and ('Gene_In_Chromosomal_Location' some '7q21.3')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162415</classIRI>
<classLabel>LIN37 Gene</classLabel>
<newAxiom>'LIN37 Gene' SubClassOf 'Cell Cycle Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162414</classIRI>
<classLabel>Transcription Factor E2F5</classLabel>
<newAxiom>'Transcription Factor E2F5' EquivalentTo 'Transcription Factor' and ('Gene_Product_Is_Element_In_Pathway' some 'Cell Cycle Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'TGF-beta Signaling Pathway KEGG') and ('Gene_Product_Is_Element_In_Pathway' some 'E2F Transcription Factor Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Regulation of Nuclear SMAD2/3 Signaling Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleus') and ('Gene_Product_Is_Physical_Part_Of' some 'DREAM Complex') and ('Gene_Product_Has_Biochemical_Function' some 'E2F Transcription Factor Family') and ('Gene_Product_Has_Biochemical_Function' some 'Sequence-Specific DNA Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Microtubule Polymerization Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Cycle Regulation Process') and ('Gene_Product_Encoded_By_Gene' some 'E2F5 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162413</classIRI>
<classLabel>E2F5 wt Allele</classLabel>
<newAxiom>'E2F5 wt Allele' EquivalentTo 'E2F5 Gene' and ('Gene_Is_Element_In_Pathway' some 'Cell Cycle Pathway') and ('Gene_Is_Element_In_Pathway' some 'TGF-beta Signaling Pathway KEGG') and ('Gene_Is_Element_In_Pathway' some 'E2F Transcription Factor Pathway') and ('Gene_Is_Element_In_Pathway' some 'Regulation of Nuclear SMAD2/3 Signaling Pathway')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162412</classIRI>
<classLabel>E2F5 Gene</classLabel>
<newAxiom>'E2F5 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Microtubule Polymerization Process'</newAxiom>
<newAxiom>'E2F5 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell Cycle Regulation Process'</newAxiom>
<newAxiom>'E2F5 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Activation'</newAxiom>
<newAxiom>'E2F5 Gene' SubClassOf 'Transcription Factor Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162419</classIRI>
<classLabel>LIN52 wt Allele</classLabel>
<newAxiom>'LIN52 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '14q24.3'</newAxiom>
<newAxiom>'LIN52 wt Allele' SubClassOf 'LIN52 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162418</classIRI>
<classLabel>LIN52 Gene</classLabel>
<newAxiom>'LIN52 Gene' SubClassOf 'Cell Cycle Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162417</classIRI>
<classLabel>Protein Lin-37 Homolog</classLabel>
<newAxiom>'Protein Lin-37 Homolog' SubClassOf 'Cell Cycle Protein'</newAxiom>
<newAxiom>'Protein Lin-37 Homolog' SubClassOf 'Gene_Product_Is_Physical_Part_Of' some 'DREAM Complex'</newAxiom>
<newAxiom>'Protein Lin-37 Homolog' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'LIN37 Gene'</newAxiom>
<newAxiom>'Protein Lin-37 Homolog' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Nucleus'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162416</classIRI>
<classLabel>LIN37 wt Allele</classLabel>
<newAxiom>'LIN37 wt Allele' SubClassOf 'LIN37 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162491</classIRI>
<classLabel>Paratesticular Region</classLabel>
<newAxiom>'Paratesticular Region' SubClassOf 'Body Region'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162490</classIRI>
<classLabel>Paratesticular Paraganglioma</classLabel>
<newAxiom>'Paratesticular Paraganglioma' EquivalentTo 'Paratesticular Neoplasm' and 'Extra-Adrenal Paraganglioma' and ('Disease_Has_Primary_Anatomic_Site' some 'Paratesticular Region')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162484</classIRI>
<classLabel>Polymerase Proofreading Associated Polyposis</classLabel>
<newAxiom>'Polymerase Proofreading Associated Polyposis' EquivalentTo 'Hereditary Neoplastic Syndrome' and 'Multiple Adenomatous Polyps' and 'Colorectal Adenomatous Polyp' and ('Disease_Mapped_To_Gene' some 'POLD1 Gene') and ('Disease_Mapped_To_Gene' some 'POLE Gene') and ('Disease_May_Have_Molecular_Abnormality' some 'POLE Gene Mutation') and ('Disease_May_Have_Molecular_Abnormality' some 'POLD1 Gene Mutation')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162483</classIRI>
<classLabel>Epididymal Cystadenoma</classLabel>
<newAxiom>'Epididymal Cystadenoma' EquivalentTo 'Cystadenoma' and 'Benign Epididymal Neoplasm' and 'Benign Epithelial Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162482</classIRI>
<classLabel>Autologous CD138-specific CAR T-cells</classLabel>
<newAxiom>'Autologous CD138-specific CAR T-cells' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous CD138-specific CAR T-cells' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Autologous CD138-specific CAR T-cells' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162481</classIRI>
<classLabel>Autologous c-Met/PD-L1-specific CAR T-cells</classLabel>
<newAxiom>'Autologous c-Met/PD-L1-specific CAR T-cells' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Autologous c-Met/PD-L1-specific CAR T-cells' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous c-Met/PD-L1-specific CAR T-cells' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162488</classIRI>
<classLabel>Epididymal Melanotic Neuroectodermal Tumor</classLabel>
<newAxiom>'Epididymal Melanotic Neuroectodermal Tumor' EquivalentTo 'Paratesticular Melanotic Neuroectodermal Tumor' and 'Epididymal Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Epididymis')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162487</classIRI>
<classLabel>Paratesticular Melanotic Neuroectodermal Tumor</classLabel>
<newAxiom>'Paratesticular Melanotic Neuroectodermal Tumor' EquivalentTo 'Paratesticular Neoplasm' and 'Melanotic Neuroectodermal Tumor' and ('Disease_Has_Primary_Anatomic_Site' some 'Paratesticular Region')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162486</classIRI>
<classLabel>Paratesticular Squamous Cell Carcinoma</classLabel>
<newAxiom>'Paratesticular Squamous Cell Carcinoma' EquivalentTo 'Paratesticular Neoplasm' and 'Squamous Cell Carcinoma' and 'Malignant Male Reproductive System Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Paratesticular Region')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162485</classIRI>
<classLabel>Paratesticular Neoplasm</classLabel>
<newAxiom>'Paratesticular Neoplasm' EquivalentTo 'Male Reproductive System Neoplasm' and ('Disease_Has_Associated_Anatomic_Site' some 'Paratesticular Region')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162489</classIRI>
<classLabel>Paratesticular Wilms Tumor</classLabel>
<newAxiom>'Paratesticular Wilms Tumor' EquivalentTo 'Paratesticular Neoplasm' and 'Wilms Tumor' and 'Malignant Male Reproductive System Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Paratesticular Region')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162495</classIRI>
<classLabel>Paratesticular Leiomyosarcoma</classLabel>
<newAxiom>'Paratesticular Leiomyosarcoma' EquivalentTo 'Paratesticular Soft Tissue Neoplasm' and 'Leiomyosarcoma' and 'Malignant Male Reproductive System Neoplasm' and 'Soft Tissue Sarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162494</classIRI>
<classLabel>Paratesticular Leiomyoma</classLabel>
<newAxiom>'Paratesticular Leiomyoma' EquivalentTo 'Paratesticular Soft Tissue Neoplasm' and 'Leiomyoma' and 'Benign Male Reproductive System Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162493</classIRI>
<classLabel>Paratesticular Liposarcoma</classLabel>
<newAxiom>'Paratesticular Liposarcoma' EquivalentTo 'Paratesticular Soft Tissue Neoplasm' and 'Liposarcoma' and 'Malignant Male Reproductive System Neoplasm' and 'Soft Tissue Sarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162492</classIRI>
<classLabel>Paratesticular Soft Tissue Neoplasm</classLabel>
<newAxiom>'Paratesticular Soft Tissue Neoplasm' EquivalentTo 'Paratesticular Neoplasm' and 'Soft Tissue Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Paratesticular Region') and ('Disease_Has_Normal_Tissue_Origin' some 'Paratesticular Soft Tissue')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162498</classIRI>
<classLabel>Paratesticular Cellular Angiofibroma</classLabel>
<newAxiom>'Paratesticular Cellular Angiofibroma' EquivalentTo 'Paratesticular Soft Tissue Neoplasm' and 'Cellular Angiofibroma' and 'Benign Male Reproductive System Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162497</classIRI>
<classLabel>Paratesticular Rhabdomyosarcoma</classLabel>
<newAxiom>'Paratesticular Rhabdomyosarcoma' EquivalentTo 'Paratesticular Soft Tissue Neoplasm' and 'Rhabdomyosarcoma' and 'Malignant Male Reproductive System Neoplasm' and 'Soft Tissue Sarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162496</classIRI>
<classLabel>Paratesticular Rhabdomyoma</classLabel>
<newAxiom>'Paratesticular Rhabdomyoma' EquivalentTo 'Paratesticular Soft Tissue Neoplasm' and 'Benign Male Reproductive System Neoplasm' and 'Extracardiac Rhabdomyoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162462</classIRI>
<classLabel>Anti-MAGE-A4 T-cell Receptor/Anti-CD3 scFv Fusion Protein IMC-C103C</classLabel>
<newAxiom>'Anti-MAGE-A4 T-cell Receptor/Anti-CD3 scFv Fusion Protein IMC-C103C' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162461</classIRI>
<classLabel>Metastatic Thymic Neuroendocrine Neoplasm</classLabel>
<newAxiom>'Metastatic Thymic Neuroendocrine Neoplasm' EquivalentTo 'Metastatic Neuroendocrine Neoplasm' and 'Thymic Neuroendocrine Neoplasm' and 'Malignant Thymus Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162460</classIRI>
<classLabel>Thymic Neuroendocrine Neoplasm</classLabel>
<newAxiom>'Thymic Neuroendocrine Neoplasm' EquivalentTo 'Neuroendocrine Neoplasm' and 'Thymic Epithelial Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Thymus Gland') and ('Disease_Has_Normal_Tissue_Origin' some 'Thymic Epithelial Tissue') and ('Disease_Has_Normal_Cell_Origin' some 'Thymic Epithelial Cell')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162466</classIRI>
<classLabel>Intratubular Large Cell Hyalinizing Sertoli Cell Neoplasia</classLabel>
<newAxiom>'Intratubular Large Cell Hyalinizing Sertoli Cell Neoplasia' EquivalentTo 'Testicular Sex Cord-Stromal Tumor' and ('Disease_Has_Abnormal_Cell' some 'Neoplastic Large Polygonal Sertoli Cell') and ('Disease_Has_Molecular_Abnormality' some 'STK11 Gene Mutation') and ('Disease_Has_Finding' some 'Dense Eosinophilic Basement Membrane Deposit') and ('Disease_May_Have_Associated_Disease' some 'Peutz-Jeghers Syndrome') and ('Disease_Mapped_To_Gene' some 'STK11 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162465</classIRI>
<classLabel>Fundus Autofluorescence Imaging</classLabel>
<newAxiom>'Fundus Autofluorescence Imaging' SubClassOf 'Eye Examination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162464</classIRI>
<classLabel>Spectral Domain-Optical Coherence Tomography</classLabel>
<newAxiom>'Spectral Domain-Optical Coherence Tomography' SubClassOf 'Optical Coherence Tomography'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162463</classIRI>
<classLabel>10-2 Visual Field Testing</classLabel>
<newAxiom>'10-2 Visual Field Testing' SubClassOf 'Eye Examination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162469</classIRI>
<classLabel>Testicular Myeloid Sarcoma</classLabel>
<newAxiom>'Testicular Myeloid Sarcoma' EquivalentTo 'Myeloid Sarcoma' and 'Malignant Testicular Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Testis')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162468</classIRI>
<classLabel>Testicular Nasal Type Extranodal NK/T-Cell Lymphoma</classLabel>
<newAxiom>'Testicular Nasal Type Extranodal NK/T-Cell Lymphoma' EquivalentTo 'Nasal Type Extranodal NK/T-Cell Lymphoma' and 'Testicular Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162467</classIRI>
<classLabel>Testicular Diffuse Large B-Cell Lymphoma</classLabel>
<newAxiom>'Testicular Diffuse Large B-Cell Lymphoma' EquivalentTo 'Testicular Lymphoma' and 'Diffuse Large B-Cell Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162480</classIRI>
<classLabel>MetAP2 Inhibitor APL-1202</classLabel>
<newAxiom>'MetAP2 Inhibitor APL-1202' SubClassOf 'Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162473</classIRI>
<classLabel>Canine Transmissible Venereal Tumor</classLabel>
<newAxiom>'Canine Transmissible Venereal Tumor' SubClassOf 'Canine Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162472</classIRI>
<classLabel>Early Infantile Epileptic Encephalopathy 4</classLabel>
<newAxiom>'Early Infantile Epileptic Encephalopathy 4' SubClassOf 'Early Infantile Epileptic Encephalopathy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162471</classIRI>
<classLabel>Specify Other HPV Typing Method</classLabel>
<newAxiom>'Specify Other HPV Typing Method' SubClassOf 'Specify Other'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162470</classIRI>
<classLabel>Testicular Plasmacytoma</classLabel>
<newAxiom>'Testicular Plasmacytoma' EquivalentTo 'Extraosseous Plasmacytoma' and 'Malignant Testicular Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Testis')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162477</classIRI>
<classLabel>Paratesticular Malignant Mesothelioma</classLabel>
<newAxiom>'Paratesticular Malignant Mesothelioma' EquivalentTo 'Paratesticular Neoplasm' and 'Malignant Mesothelioma' and 'Malignant Male Reproductive System Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Tunica Vaginalis')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162476</classIRI>
<classLabel>Paratesticular Adenomatoid Tumor</classLabel>
<newAxiom>'Paratesticular Adenomatoid Tumor' EquivalentTo 'Paratesticular Neoplasm' and 'Adenomatoid Tumor' and 'Benign Male Reproductive System Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Paratesticular Region')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162475</classIRI>
<classLabel>Advanced Colorectal Carcinoma</classLabel>
<newAxiom>'Advanced Colorectal Carcinoma' EquivalentTo 'Metastatic Colorectal Carcinoma' and 'Advanced Digestive System Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162474</classIRI>
<classLabel>Epidermolysis Bullosa, Junctional, with Pyloric Atresia</classLabel>
<newAxiom>'Epidermolysis Bullosa, Junctional, with Pyloric Atresia' SubClassOf 'Junctional Epidermolysis Bullosa'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162479</classIRI>
<classLabel>BTK inhibitor TG-1701</classLabel>
<newAxiom>'BTK inhibitor TG-1701' SubClassOf 'BTK Inhibitor'</newAxiom>
<newAxiom>'BTK inhibitor TG-1701' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162478</classIRI>
<classLabel>EMSY Gene Mutation</classLabel>
<newAxiom>'EMSY Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'EMSY Gene'</newAxiom>
<newAxiom>'EMSY Gene Mutation' SubClassOf 'Gene Mutant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162440</classIRI>
<classLabel>Protein Fem-1 Homolog C</classLabel>
<newAxiom>'Protein Fem-1 Homolog C' EquivalentTo 'Ubiquitination Regulation Protein' and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Ankyrin Repeat') and ('Gene_Product_Is_Physical_Part_Of' some 'Ubiquitin Protein Ligase') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Ubiquitination') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Ubiquitinated Protein Degradation') and ('Gene_Product_Encoded_By_Gene' some 'FEM1C Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162444</classIRI>
<classLabel>TXK Gene</classLabel>
<newAxiom>'TXK Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Tyrosine Phosphorylation'</newAxiom>
<newAxiom>'TXK Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Signal Transduction'</newAxiom>
<newAxiom>'TXK Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Host Defense Mechanism'</newAxiom>
<newAxiom>'TXK Gene' SubClassOf 'Non-Receptor Tyrosine Kinase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162443</classIRI>
<classLabel>Recurrent Rectal Adenocarcinoma</classLabel>
<newAxiom>'Recurrent Rectal Adenocarcinoma' EquivalentTo 'Recurrent Colorectal Adenocarcinoma' and 'Recurrent Rectal Carcinoma' and 'Rectal Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162442</classIRI>
<classLabel>Recurrent Colon Adenocarcinoma</classLabel>
<newAxiom>'Recurrent Colon Adenocarcinoma' EquivalentTo 'Recurrent Colorectal Adenocarcinoma' and 'Recurrent Colon Carcinoma' and 'Colon Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162441</classIRI>
<classLabel>Recurrent Colorectal Adenocarcinoma</classLabel>
<newAxiom>'Recurrent Colorectal Adenocarcinoma' EquivalentTo 'Recurrent Adenocarcinoma' and 'Colorectal Adenocarcinoma' and 'Recurrent Colorectal Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162448</classIRI>
<classLabel>COL7A1 Gene Mutation</classLabel>
<newAxiom>'COL7A1 Gene Mutation' SubClassOf 'Gene Mutant'</newAxiom>
<newAxiom>'COL7A1 Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'COL7A1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162447</classIRI>
<classLabel>Tyrosine-Protein Kinase TXK</classLabel>
<newAxiom>'Tyrosine-Protein Kinase TXK' EquivalentTo 'Protein Tyrosine Kinase' and 'Signaling Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Leukocyte Transendothelial Migration Pathway') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'SH2 Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'SH3 Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Nuclear Localization Signal') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Signal Transduction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Tyrosine Phosphorylation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Host Defense Mechanism') and ('Gene_Product_Encoded_By_Gene' some 'TXK Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162445</classIRI>
<classLabel>TXK wt Allele</classLabel>
<newAxiom>'TXK wt Allele' SubClassOf 'TXK Gene'</newAxiom>
<newAxiom>'TXK wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '4p12'</newAxiom>
<newAxiom>'TXK wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Leukocyte Transendothelial Migration Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162449</classIRI>
<classLabel>Peptide Receptor Radionuclide Therapy</classLabel>
<newAxiom>'Peptide Receptor Radionuclide Therapy' SubClassOf 'Isotope Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162451</classIRI>
<classLabel>Recurrent High Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements</classLabel>
<newAxiom>'Recurrent High Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements' EquivalentTo 'High Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements' and 'Recurrent High Grade B-Cell Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162450</classIRI>
<classLabel>Refractory Hepatocellular Carcinoma</classLabel>
<newAxiom>'Refractory Hepatocellular Carcinoma' EquivalentTo 'Refractory Liver Carcinoma' and 'Refractory Adenocarcinoma' and 'Hepatocellular Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162455</classIRI>
<classLabel>Dupilumab</classLabel>
<newAxiom>'Dupilumab' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162454</classIRI>
<classLabel>Protein Arginine Methyltransferase 5 Inhibitor PRT543</classLabel>
<newAxiom>'Protein Arginine Methyltransferase 5 Inhibitor PRT543' SubClassOf 'Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162453</classIRI>
<classLabel>Refractory High Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements</classLabel>
<newAxiom>'Refractory High Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements' EquivalentTo 'High Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements' and 'Refractory High Grade B-Cell Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162452</classIRI>
<classLabel>Antisense Oligonucleotide QR-313</classLabel>
<newAxiom>'Antisense Oligonucleotide QR-313' SubClassOf 'Antisense Oligonucleotides'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162459</classIRI>
<classLabel>HPV16 E7-specific HLA-A*02:01-restricted IgG1-Fc Fusion Protein CUE-101</classLabel>
<newAxiom>'HPV16 E7-specific HLA-A*02:01-restricted IgG1-Fc Fusion Protein CUE-101' SubClassOf 'Immunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162458</classIRI>
<classLabel>Refractory Intermediate Risk Acute Myeloid Leukemia</classLabel>
<newAxiom>'Refractory Intermediate Risk Acute Myeloid Leukemia' SubClassOf 'Intermediate Risk Acute Myeloid Leukemia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162457</classIRI>
<classLabel>Refractory High Risk Acute Myeloid Leukemia</classLabel>
<newAxiom>'Refractory High Risk Acute Myeloid Leukemia' SubClassOf 'High Risk Acute Myeloid Leukemia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162456</classIRI>
<classLabel>Intermediate Risk Acute Myeloid Leukemia</classLabel>
<newAxiom>'Intermediate Risk Acute Myeloid Leukemia' SubClassOf 'Hematopoietic System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162422</classIRI>
<classLabel>Protein Lin-54 Homolog</classLabel>
<newAxiom>'Protein Lin-54 Homolog' EquivalentTo 'Transcription Factor' and 'Cell Cycle Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleus') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'DNA Binding Domain') and ('Gene_Product_Is_Physical_Part_Of' some 'DREAM Complex') and ('Gene_Product_Has_Biochemical_Function' some 'Sequence-Specific DNA Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Regulation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Cycle Regulation Process') and ('Gene_Product_Encoded_By_Gene' some 'LIN54 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162421</classIRI>
<classLabel>LIN54 Gene</classLabel>
<newAxiom>'LIN54 Gene' SubClassOf 'Cell Cycle Gene'</newAxiom>
<newAxiom>'LIN54 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'DNA Binding'</newAxiom>
<newAxiom>'LIN54 Gene' SubClassOf 'Transcription Factor Gene'</newAxiom>
<newAxiom>'LIN54 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell Cycle Regulation Process'</newAxiom>
<newAxiom>'LIN54 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Regulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162420</classIRI>
<classLabel>Protein Lin-52 Homolog</classLabel>
<newAxiom>'Protein Lin-52 Homolog' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'LIN52 Gene'</newAxiom>
<newAxiom>'Protein Lin-52 Homolog' SubClassOf 'Gene_Product_Is_Physical_Part_Of' some 'DREAM Complex'</newAxiom>
<newAxiom>'Protein Lin-52 Homolog' SubClassOf 'Cell Cycle Protein'</newAxiom>
<newAxiom>'Protein Lin-52 Homolog' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Nucleus'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162426</classIRI>
<classLabel>RAB44 Gene</classLabel>
<newAxiom>'RAB44 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Neutrophil Activation'</newAxiom>
<newAxiom>'RAB44 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Signal Transduction'</newAxiom>
<newAxiom>'RAB44 Gene' SubClassOf 'RAS Family Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162425</classIRI>
<classLabel>Refractory Myelofibrosis</classLabel>
<newAxiom>'Refractory Myelofibrosis' SubClassOf 'Myelofibrosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162424</classIRI>
<classLabel>Recurrent Myelofibrosis</classLabel>
<newAxiom>'Recurrent Myelofibrosis' SubClassOf 'Myelofibrosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162423</classIRI>
<classLabel>LIN54 wt Allele</classLabel>
<newAxiom>'LIN54 wt Allele' SubClassOf 'LIN54 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162429</classIRI>
<classLabel>KLHL33 Gene</classLabel>
<newAxiom>'KLHL33 Gene' SubClassOf 'Regulatory Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162428</classIRI>
<classLabel>Ras-Related Protein Rab-44</classLabel>
<newAxiom>'Ras-Related Protein Rab-44' EquivalentTo 'RAS Superfamily Protein' and ('Gene_Product_Has_Chemical_Classification' some 'Membrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'EF-Hand Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Coiled-Coil Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Proline-Rich Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Signal Transduction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Neutrophil Activation') and ('Gene_Product_Encoded_By_Gene' some 'RAB44 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162427</classIRI>
<classLabel>RAB44 wt Allele</classLabel>
<newAxiom>'RAB44 wt Allele' SubClassOf 'RAB44 Gene'</newAxiom>
<newAxiom>'RAB44 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '6p21.2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162433</classIRI>
<classLabel>NCSTN wt Allele</classLabel>
<newAxiom>'NCSTN wt Allele' EquivalentTo 'NCSTN Gene' and ('Gene_Is_Element_In_Pathway' some 'Alzheimer's Disease Pathway KEGG') and ('Gene_Is_Element_In_Pathway' some 'Notch Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Nerve Growth Factor Receptor Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Presenilin Action in Notch and Wnt Signaling Pathways') and ('Gene_Is_Element_In_Pathway' some 'Syndecan-3-Mediated Signaling Pathway') and ('Gene_In_Chromosomal_Location' some '1q23.2')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162432</classIRI>
<classLabel>NCSTN Gene</classLabel>
<newAxiom>'NCSTN Gene' SubClassOf 'Regulatory Gene'</newAxiom>
<newAxiom>'NCSTN Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Regulated Intramembrane Proteolysis'</newAxiom>
<newAxiom>'NCSTN Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Intercellular Communication Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162431</classIRI>
<classLabel>Kelch-Like Protein 33</classLabel>
<newAxiom>'Kelch-Like Protein 33' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'BTB/POZ Domain'</newAxiom>
<newAxiom>'Kelch-Like Protein 33' SubClassOf 'Regulatory Protein'</newAxiom>
<newAxiom>'Kelch-Like Protein 33' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'KLHL33 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162430</classIRI>
<classLabel>KLHL33 wt Allele</classLabel>
<newAxiom>'KLHL33 wt Allele' SubClassOf 'KLHL33 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162437</classIRI>
<classLabel>Syntaxin-7</classLabel>
<newAxiom>'Syntaxin-7' EquivalentTo 'Transport Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'SNARE Proteins Vesicular Transport Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Phagocytosis Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Early Endosome') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Endosome') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Coiled-Coil Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Endocytotic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Subcellular Protein Targeting') and ('Gene_Product_Encoded_By_Gene' some 'STX7 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162436</classIRI>
<classLabel>STX7 wt Allele</classLabel>
<newAxiom>'STX7 wt Allele' SubClassOf 'STX7 Gene'</newAxiom>
<newAxiom>'STX7 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Phagocytosis Pathway'</newAxiom>
<newAxiom>'STX7 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'SNARE Proteins Vesicular Transport Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162435</classIRI>
<classLabel>STX7 Gene</classLabel>
<newAxiom>'STX7 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Subcellular Protein Targeting'</newAxiom>
<newAxiom>'STX7 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Endocytotic Process'</newAxiom>
<newAxiom>'STX7 Gene' SubClassOf 'Trafficking Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162434</classIRI>
<classLabel>Nicastrin</classLabel>
<newAxiom>'Nicastrin' EquivalentTo 'Regulatory Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Alzheimer's Disease Pathway KEGG') and ('Gene_Product_Is_Element_In_Pathway' some 'Notch Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Nerve Growth Factor Receptor Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Presenilin Action in Notch and Wnt Signaling Pathways') and ('Gene_Product_Is_Element_In_Pathway' some 'Syndecan-3-Mediated Signaling Pathway') and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Cellular Membrane') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Is_Physical_Part_Of' some 'Gamma Secretase') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Intercellular Communication Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Regulated Intramembrane Proteolysis') and ('Gene_Product_Encoded_By_Gene' some 'NCSTN Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162439</classIRI>
<classLabel>FEM1C wt Allele</classLabel>
<newAxiom>'FEM1C wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '5q22.3'</newAxiom>
<newAxiom>'FEM1C wt Allele' SubClassOf 'FEM1C Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162438</classIRI>
<classLabel>FEM1C Gene</classLabel>
<newAxiom>'FEM1C Gene' SubClassOf 'Regulatory Gene'</newAxiom>
<newAxiom>'FEM1C Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Degradation Process'</newAxiom>
<newAxiom>'FEM1C Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Ubiquitination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162194</classIRI>
<classLabel>Advanced Soft Tissue Sarcoma</classLabel>
<newAxiom>'Advanced Soft Tissue Sarcoma' EquivalentTo 'Metastatic Soft Tissue Sarcoma' and 'Advanced Sarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162193</classIRI>
<classLabel>Pollen Extract PCC-100</classLabel>
<newAxiom>'Pollen Extract PCC-100' SubClassOf 'Plant or Plant Part Extract'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162192</classIRI>
<classLabel>Furosemide/Digoxin Topical Gel CLS003</classLabel>
<newAxiom>'Furosemide/Digoxin Topical Gel CLS003' SubClassOf 'Antiviral Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162191</classIRI>
<classLabel>Monoclonal Hematopoietic Stem and Progenitor Cells Present</classLabel>
<newAxiom>'Monoclonal Hematopoietic Stem and Progenitor Cells Present' SubClassOf 'Monoclonal Cellular Population Present'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162187</classIRI>
<classLabel>Microbial Ecosystem Therapeutics-4</classLabel>
<newAxiom>'Microbial Ecosystem Therapeutics-4' SubClassOf 'Dietary Supplement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162186</classIRI>
<classLabel>mRNA-derived KRAS-targeted Vaccine V941</classLabel>
<newAxiom>'mRNA-derived KRAS-targeted Vaccine V941' SubClassOf 'Antineoplastic Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162185</classIRI>
<classLabel>Ibrexafungerp</classLabel>
<newAxiom>'Ibrexafungerp' SubClassOf 'Antifungal Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162184</classIRI>
<classLabel>Somatic BRCA1 Gene Mutation</classLabel>
<newAxiom>'Somatic BRCA1 Gene Mutation' SubClassOf 'BRCA1 Gene Mutation'</newAxiom>
<newAxiom>'Somatic BRCA1 Gene Mutation' SubClassOf 'Somatic Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162188</classIRI>
<classLabel>Clonal Hematopoiesis</classLabel>
<newAxiom>'Clonal Hematopoiesis' EquivalentTo 'Premalignant Hematologic Condition' and ('Disease_Has_Finding' some 'Monoclonal Cellular Population Present')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162198</classIRI>
<classLabel>Musculoskeletal Findings, Connective and Soft Tissue Findings Sponsor-Defined Identifier</classLabel>
<newAxiom>'Musculoskeletal Findings, Connective and Soft Tissue Findings Sponsor-Defined Identifier' SubClassOf 'Sponsor ID'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162197</classIRI>
<classLabel>Respiratory System Findings Sponsor-Defined Identifier</classLabel>
<newAxiom>'Respiratory System Findings Sponsor-Defined Identifier' SubClassOf 'Sponsor ID'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162196</classIRI>
<classLabel>Sponsor-Defined Identifier</classLabel>
<newAxiom>'Sponsor-Defined Identifier' SubClassOf 'Retired Concept Current Year'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162195</classIRI>
<classLabel>Focus of Study-Specific Interest</classLabel>
<newAxiom>'Focus of Study-Specific Interest' SubClassOf 'Identification'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162199</classIRI>
<classLabel>Nervous System Sponsor-Defined Identifier</classLabel>
<newAxiom>'Nervous System Sponsor-Defined Identifier' SubClassOf 'Sponsor ID'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162172</classIRI>
<classLabel>Participation End Date</classLabel>
<newAxiom>'Participation End Date' SubClassOf 'End Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162171</classIRI>
<classLabel>Informed Consent Time</classLabel>
<newAxiom>'Informed Consent Time' SubClassOf 'Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162170</classIRI>
<classLabel>Last Study Treatment Time</classLabel>
<newAxiom>'Last Study Treatment Time' SubClassOf 'Time of Therapeutic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162165</classIRI>
<classLabel>First Study Treatment Date</classLabel>
<newAxiom>'First Study Treatment Date' SubClassOf 'Date of Therapeutic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162164</classIRI>
<classLabel>Cholic Acid-24-13C</classLabel>
<newAxiom>'Cholic Acid-24-13C' SubClassOf 'Radioconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162163</classIRI>
<classLabel>Cholic-2,2,4,4-D4 Acid</classLabel>
<newAxiom>'Cholic-2,2,4,4-D4 Acid' SubClassOf 'Radioconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162162</classIRI>
<classLabel>Cholate Clearance Test</classLabel>
<newAxiom>'Cholate Clearance Test' SubClassOf 'Liver Function Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162169</classIRI>
<classLabel>First Study Treatment Time</classLabel>
<newAxiom>'First Study Treatment Time' SubClassOf 'Time of Therapeutic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162168</classIRI>
<classLabel>Time of Therapeutic Procedure</classLabel>
<newAxiom>'Time of Therapeutic Procedure' SubClassOf 'Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162167</classIRI>
<classLabel>Last Study Treatment Date</classLabel>
<newAxiom>'Last Study Treatment Date' SubClassOf 'Date of Therapeutic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162166</classIRI>
<classLabel>MOv19 CAR-CD3zeta-4-1BB-expressing Allogeneic T-lymphocytes</classLabel>
<newAxiom>'MOv19 CAR-CD3zeta-4-1BB-expressing Allogeneic T-lymphocytes' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'MOv19 CAR-CD3zeta-4-1BB-expressing Allogeneic T-lymphocytes' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'MOv19 CAR-CD3zeta-4-1BB-expressing Allogeneic T-lymphocytes' SubClassOf 'Therapeutic Allogeneic Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162183</classIRI>
<classLabel>Somatic BRCA2 Gene Mutation</classLabel>
<newAxiom>'Somatic BRCA2 Gene Mutation' SubClassOf 'Somatic Mutation'</newAxiom>
<newAxiom>'Somatic BRCA2 Gene Mutation' SubClassOf 'BRCA2 Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162182</classIRI>
<classLabel>Locally Advanced Unresectable Breast Carcinoma</classLabel>
<newAxiom>'Locally Advanced Unresectable Breast Carcinoma' EquivalentTo 'Locally Advanced Unresectable Carcinoma' and 'Unresectable Breast Carcinoma' and 'Locally Advanced Breast Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162181</classIRI>
<classLabel>Tumor Results Measurement Time</classLabel>
<newAxiom>'Tumor Results Measurement Time' SubClassOf 'Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162180</classIRI>
<classLabel>Tumor Results Measurement Date</classLabel>
<newAxiom>'Tumor Results Measurement Date' SubClassOf 'Assessment Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162176</classIRI>
<classLabel>Study Subject Assessment Date</classLabel>
<newAxiom>'Study Subject Assessment Date' SubClassOf 'Assessment Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162175</classIRI>
<classLabel>Disease Response Assessment Time</classLabel>
<newAxiom>'Disease Response Assessment Time' SubClassOf 'Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162174</classIRI>
<classLabel>Disease Response Assessment Date</classLabel>
<newAxiom>'Disease Response Assessment Date' SubClassOf 'Assessment Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162173</classIRI>
<classLabel>Participation End Time</classLabel>
<newAxiom>'Participation End Time' SubClassOf 'End Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162179</classIRI>
<classLabel>Tumor Identification Time</classLabel>
<newAxiom>'Tumor Identification Time' SubClassOf 'Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162178</classIRI>
<classLabel>Tumor Identification Date</classLabel>
<newAxiom>'Tumor Identification Date' SubClassOf 'Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162177</classIRI>
<classLabel>Study Subject Assessment Time</classLabel>
<newAxiom>'Study Subject Assessment Time' SubClassOf 'Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162150</classIRI>
<classLabel>Microbiology Susceptibility Analysis Method</classLabel>
<newAxiom>'Microbiology Susceptibility Analysis Method' SubClassOf 'Analysis Method'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162143</classIRI>
<classLabel>Microbiology Specimen Focus of Study-Specific Interest</classLabel>
<newAxiom>'Microbiology Specimen Focus of Study-Specific Interest' SubClassOf 'Focus of Study-Specific Interest'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162142</classIRI>
<classLabel>HLA-C*08 Positive Cells Present</classLabel>
<newAxiom>'HLA-C*08 Positive Cells Present' SubClassOf 'Positive Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162141</classIRI>
<classLabel>Invasive Pulmonary Aspergillosis</classLabel>
<newAxiom>'Invasive Pulmonary Aspergillosis' SubClassOf 'Aspergillosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162140</classIRI>
<classLabel>Meal Data Name</classLabel>
<newAxiom>'Meal Data Name' SubClassOf 'Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162147</classIRI>
<classLabel>Microbiology Susceptibility Agent Name</classLabel>
<newAxiom>'Microbiology Susceptibility Agent Name' SubClassOf 'Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162146</classIRI>
<classLabel>Microbiology Susceptibility Measurement, Test or Examination Detail</classLabel>
<newAxiom>'Microbiology Susceptibility Measurement, Test or Examination Detail' SubClassOf 'Measurement, Test or Examination Detail'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162145</classIRI>
<classLabel>Microbiology Susceptibility Non-host Organism Identifier</classLabel>
<newAxiom>'Microbiology Susceptibility Non-host Organism Identifier' SubClassOf 'Identifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162144</classIRI>
<classLabel>Microbiology Specimen Measurement, Test or Examination Detail</classLabel>
<newAxiom>'Microbiology Specimen Measurement, Test or Examination Detail' SubClassOf 'Measurement, Test or Examination Detail'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162149</classIRI>
<classLabel>Microbiology Susceptibility External File Path</classLabel>
<newAxiom>'Microbiology Susceptibility External File Path' SubClassOf 'Pathname'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162148</classIRI>
<classLabel>Microbiology Susceptibility Modified Reported Name</classLabel>
<newAxiom>'Microbiology Susceptibility Modified Reported Name' SubClassOf 'Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162161</classIRI>
<classLabel>Liver-directed Therapy</classLabel>
<newAxiom>'Liver-directed Therapy' SubClassOf 'Local Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162160</classIRI>
<classLabel>Community Health Advisor</classLabel>
<newAxiom>'Community Health Advisor' SubClassOf 'Personnel'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162154</classIRI>
<classLabel>Refractory Colorectal Adenocarcinoma</classLabel>
<newAxiom>'Refractory Colorectal Adenocarcinoma' EquivalentTo 'Refractory Colorectal Carcinoma' and 'Refractory Adenocarcinoma' and 'Colorectal Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162153</classIRI>
<classLabel>Advanced Pancreatic Adenocarcinoma</classLabel>
<newAxiom>'Advanced Pancreatic Adenocarcinoma' EquivalentTo 'Advanced Digestive System Carcinoma' and 'Advanced Adenocarcinoma' and 'Metastatic Pancreatic Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162152</classIRI>
<classLabel>Advanced Colon Adenocarcinoma</classLabel>
<newAxiom>'Advanced Colon Adenocarcinoma' EquivalentTo 'Advanced Adenocarcinoma' and 'Metastatic Colon Adenocarcinoma' and 'Advanced Colorectal Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162151</classIRI>
<classLabel>Microbiology Susceptibility Collected Duration</classLabel>
<newAxiom>'Microbiology Susceptibility Collected Duration' SubClassOf 'Duration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162158</classIRI>
<classLabel>Advanced Lung Non-Small Cell Carcinoma</classLabel>
<newAxiom>'Advanced Lung Non-Small Cell Carcinoma' EquivalentTo 'Advanced Lung Carcinoma' and 'Metastatic Lung Non-Small Cell Carcinoma' and 'Lung Non-Small Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162157</classIRI>
<classLabel>Refractory Rectal Adenocarcinoma</classLabel>
<newAxiom>'Refractory Rectal Adenocarcinoma' EquivalentTo 'Refractory Colorectal Adenocarcinoma' and 'Refractory Rectal Carcinoma' and 'Rectal Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162156</classIRI>
<classLabel>Refractory Rectal Carcinoma</classLabel>
<newAxiom>'Refractory Rectal Carcinoma' EquivalentTo 'Refractory Colorectal Carcinoma' and 'Rectal Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162155</classIRI>
<classLabel>Refractory Colon Adenocarcinoma</classLabel>
<newAxiom>'Refractory Colon Adenocarcinoma' EquivalentTo 'Refractory Colon Carcinoma' and 'Refractory Colorectal Adenocarcinoma' and 'Colon Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162159</classIRI>
<classLabel>Stereotactic Accelerated Partial Breast Irradiation</classLabel>
<newAxiom>'Stereotactic Accelerated Partial Breast Irradiation' SubClassOf 'Accelerated Partial Breast Irradiation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162129</classIRI>
<classLabel>Disease Response Elapsed Time</classLabel>
<newAxiom>'Disease Response Elapsed Time' SubClassOf 'Elapsed Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162128</classIRI>
<classLabel>Description of Unplanned Actual Arm</classLabel>
<newAxiom>'Description of Unplanned Actual Arm' SubClassOf 'Description of Actual Arm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162127</classIRI>
<classLabel>Cardiovascular System Findings Reference Identifier</classLabel>
<newAxiom>'Cardiovascular System Findings Reference Identifier' SubClassOf 'Reference ID'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162132</classIRI>
<classLabel>Functional Tests Sponsor-Defined Identifier</classLabel>
<newAxiom>'Functional Tests Sponsor-Defined Identifier' SubClassOf 'Identifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162131</classIRI>
<classLabel>Functional Tests Reference Identifier</classLabel>
<newAxiom>'Functional Tests Reference Identifier' SubClassOf 'Reference ID'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162130</classIRI>
<classLabel>Disease Response Time Point Reference</classLabel>
<newAxiom>'Disease Response Time Point Reference' SubClassOf 'Reference Time Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162136</classIRI>
<classLabel>Functional Tests Elapsed Time</classLabel>
<newAxiom>'Functional Tests Elapsed Time' SubClassOf 'Elapsed Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162135</classIRI>
<classLabel>Functional Tests Vendor Name</classLabel>
<newAxiom>'Functional Tests Vendor Name' SubClassOf 'Vendor Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162134</classIRI>
<classLabel>Functional Tests External File Path</classLabel>
<newAxiom>'Functional Tests External File Path' SubClassOf 'Pathname'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162133</classIRI>
<classLabel>Functional Tests Result or Finding in Original Units</classLabel>
<newAxiom>'Functional Tests Result or Finding in Original Units' SubClassOf 'Original Result Unit'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162139</classIRI>
<classLabel>Regressed Testicular Germ Cell Tumor</classLabel>
<newAxiom>'Regressed Testicular Germ Cell Tumor' EquivalentTo 'Testicular Germ Cell Tumor' and ('Disease_Has_Finding' some 'Regression') and ('Disease_Has_Finding' some 'Scar')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162138</classIRI>
<classLabel>Meal Data Sponsor-Defined Identifier</classLabel>
<newAxiom>'Meal Data Sponsor-Defined Identifier' SubClassOf 'Identifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162137</classIRI>
<classLabel>Functional Tests Time Point Reference</classLabel>
<newAxiom>'Functional Tests Time Point Reference' SubClassOf 'Reference Time Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162293</classIRI>
<classLabel>MET NM_000245.3:c.3208GA</classLabel>
<newAxiom>'MET NM_000245.3:c.3208GA' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'MET NP_000236.2:p.V1070M'</newAxiom>
<newAxiom>'MET NM_000245.3:c.3208GA' SubClassOf 'MET Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162292</classIRI>
<classLabel>MET NP_000236.2:p.V1092I</classLabel>
<newAxiom>'MET NP_000236.2:p.V1092I' SubClassOf 'MET Protein Variant'</newAxiom>
<newAxiom>'MET NP_000236.2:p.V1092I' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MET NM_000245.3:c.3274GA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162291</classIRI>
<classLabel>MET NM_000245.3:c.3274GA</classLabel>
<newAxiom>'MET NM_000245.3:c.3274GA' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'MET NP_000236.2:p.V1092I'</newAxiom>
<newAxiom>'MET NM_000245.3:c.3274GA' SubClassOf 'MET Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162290</classIRI>
<classLabel>MET NP_000236.2:p.H1094Y</classLabel>
<newAxiom>'MET NP_000236.2:p.H1094Y' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MET NM_000245.3:c.3280CT'</newAxiom>
<newAxiom>'MET NP_000236.2:p.H1094Y' SubClassOf 'MET Protein Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162286</classIRI>
<classLabel>MET NP_000236.2:p.L1205V</classLabel>
<newAxiom>'MET NP_000236.2:p.L1205V' SubClassOf 'MET Protein Variant'</newAxiom>
<newAxiom>'MET NP_000236.2:p.L1205V' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MET NM_000245.3:c.3613TG'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162285</classIRI>
<classLabel>MET NM_000245.3:c.3613TG</classLabel>
<newAxiom>'MET NM_000245.3:c.3613TG' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'MET NP_000236.2:p.L1205V'</newAxiom>
<newAxiom>'MET NM_000245.3:c.3613TG' SubClassOf 'MET Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162284</classIRI>
<classLabel>MET NP_000236.2:p.D1228N</classLabel>
<newAxiom>'MET NP_000236.2:p.D1228N' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MET NM_000245.3:c.3682GA'</newAxiom>
<newAxiom>'MET NP_000236.2:p.D1228N' SubClassOf 'MET Protein Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162283</classIRI>
<classLabel>MET NM_000245.3:c.3682GA</classLabel>
<newAxiom>'MET NM_000245.3:c.3682GA' SubClassOf 'MET Gene Mutation'</newAxiom>
<newAxiom>'MET NM_000245.3:c.3682GA' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'MET NP_000236.2:p.D1228N'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162289</classIRI>
<classLabel>MET NM_000245.3:c.3280CT</classLabel>
<newAxiom>'MET NM_000245.3:c.3280CT' SubClassOf 'MET Gene Mutation'</newAxiom>
<newAxiom>'MET NM_000245.3:c.3280CT' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'MET NP_000236.2:p.H1094Y'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162288</classIRI>
<classLabel>MET NP_000236.2:p.F1200I</classLabel>
<newAxiom>'MET NP_000236.2:p.F1200I' SubClassOf 'MET Protein Variant'</newAxiom>
<newAxiom>'MET NP_000236.2:p.F1200I' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MET NM_000245.3:c.3598TA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162287</classIRI>
<classLabel>MET NM_000245.3:c.3598TA</classLabel>
<newAxiom>'MET NM_000245.3:c.3598TA' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'MET NP_000236.2:p.F1200I'</newAxiom>
<newAxiom>'MET NM_000245.3:c.3598TA' SubClassOf 'MET Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162297</classIRI>
<classLabel>MET NP_000236.2:p.V1070G</classLabel>
<newAxiom>'MET NP_000236.2:p.V1070G' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MET NM_000245.3:c.3209TG'</newAxiom>
<newAxiom>'MET NP_000236.2:p.V1070G' SubClassOf 'MET Protein Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162296</classIRI>
<classLabel>Anti-CD33/CD3 Bispecific Antibody JNJ-67571244</classLabel>
<newAxiom>'Anti-CD33/CD3 Bispecific Antibody JNJ-67571244' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-CD33/CD3 Bispecific Antibody JNJ-67571244' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162295</classIRI>
<classLabel>MET NM_000245.3:c.3209TG</classLabel>
<newAxiom>'MET NM_000245.3:c.3209TG' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'MET NP_000236.2:p.V1070G'</newAxiom>
<newAxiom>'MET NM_000245.3:c.3209TG' SubClassOf 'MET Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162294</classIRI>
<classLabel>MET NP_000236.2:p.V1070M</classLabel>
<newAxiom>'MET NP_000236.2:p.V1070M' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MET NM_000245.3:c.3208GA'</newAxiom>
<newAxiom>'MET NP_000236.2:p.V1070M' SubClassOf 'MET Protein Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162299</classIRI>
<classLabel>MET NP_000236.2:p.V1070E</classLabel>
<newAxiom>'MET NP_000236.2:p.V1070E' SubClassOf 'MET Protein Variant'</newAxiom>
<newAxiom>'MET NP_000236.2:p.V1070E' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MET NM_000245.3:c.3209TA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162298</classIRI>
<classLabel>MET NM_000245.3:c.3209TA</classLabel>
<newAxiom>'MET NM_000245.3:c.3209TA' SubClassOf 'MET Gene Mutation'</newAxiom>
<newAxiom>'MET NM_000245.3:c.3209TA' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'MET NP_000236.2:p.V1070E'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162271</classIRI>
<classLabel>Locally Advanced Unresectable Colon Adenocarcinoma</classLabel>
<newAxiom>'Locally Advanced Unresectable Colon Adenocarcinoma' EquivalentTo 'Metastatic Colon Adenocarcinoma' and 'Unresectable Colon Adenocarcinoma' and 'Locally Advanced Unresectable Colorectal Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162270</classIRI>
<classLabel>Locally Advanced Unresectable Colorectal Adenocarcinoma</classLabel>
<newAxiom>'Locally Advanced Unresectable Colorectal Adenocarcinoma' EquivalentTo 'Unresectable Digestive System Adenocarcinoma' and 'Locally Advanced Digestive System Carcinoma' and 'Locally Advanced Unresectable Carcinoma' and 'Metastatic Colorectal Adenocarcinoma' and 'Unresectable Colorectal Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162264</classIRI>
<classLabel>Meal Data Time Point Reference</classLabel>
<newAxiom>'Meal Data Time Point Reference' SubClassOf 'Reference Time Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162263</classIRI>
<classLabel>Meal Data Elapsed Time</classLabel>
<newAxiom>'Meal Data Elapsed Time' SubClassOf 'Elapsed Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162262</classIRI>
<classLabel>HLA-B*07 Positive Cells Present</classLabel>
<newAxiom>'HLA-B*07 Positive Cells Present' SubClassOf 'Positive Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162261</classIRI>
<classLabel>Platinum Doublet</classLabel>
<newAxiom>'Platinum Doublet' SubClassOf 'Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162268</classIRI>
<classLabel>Disease Milestone Instance Time</classLabel>
<newAxiom>'Disease Milestone Instance Time' SubClassOf 'Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162267</classIRI>
<classLabel>Disease Milestone Instance Date</classLabel>
<newAxiom>'Disease Milestone Instance Date' SubClassOf 'Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162266</classIRI>
<classLabel>Temporal Relation to Milestone Instance</classLabel>
<newAxiom>'Temporal Relation to Milestone Instance' SubClassOf 'Relationship'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162265</classIRI>
<classLabel>Disease Milestone Instance Name</classLabel>
<newAxiom>'Disease Milestone Instance Name' SubClassOf 'Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162269</classIRI>
<classLabel>Autologous mDC3/8-KRAS Vaccine</classLabel>
<newAxiom>'Autologous mDC3/8-KRAS Vaccine' SubClassOf 'Dendritic Cell Tumor Peptide Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162282</classIRI>
<classLabel>MET NP_000236.2:p.Y1230C</classLabel>
<newAxiom>'MET NP_000236.2:p.Y1230C' SubClassOf 'MET Protein Variant'</newAxiom>
<newAxiom>'MET NP_000236.2:p.Y1230C' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MET NM_000245.3:c.3689AG'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162281</classIRI>
<classLabel>MET NM_000245.3:c.3689AG</classLabel>
<newAxiom>'MET NM_000245.3:c.3689AG' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'MET NP_000236.2:p.Y1230C'</newAxiom>
<newAxiom>'MET NM_000245.3:c.3689AG' SubClassOf 'MET Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162280</classIRI>
<classLabel>MET NP_000236.2:p.Y1230H</classLabel>
<newAxiom>'MET NP_000236.2:p.Y1230H' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MET NM_000245.3:c.3688TC'</newAxiom>
<newAxiom>'MET NP_000236.2:p.Y1230H' SubClassOf 'MET Protein Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162275</classIRI>
<classLabel>Metastatic Appendix Carcinoma</classLabel>
<newAxiom>'Metastatic Appendix Carcinoma' EquivalentTo 'Metastatic Digestive System Carcinoma' and 'Appendix Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162274</classIRI>
<classLabel>Metastatic Appendix Mucinous Adenocarcinoma</classLabel>
<newAxiom>'Metastatic Appendix Mucinous Adenocarcinoma' EquivalentTo 'Metastatic Appendix Carcinoma' and 'Metastatic Adenocarcinoma' and 'Appendix Mucinous Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162273</classIRI>
<classLabel>Metastatic Colorectal Mucinous Adenocarcinoma</classLabel>
<newAxiom>'Metastatic Colorectal Mucinous Adenocarcinoma' EquivalentTo 'Metastatic Colorectal Adenocarcinoma' and 'Colorectal Mucinous Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162272</classIRI>
<classLabel>Locally Advanced Unresectable Rectal Adenocarcinoma</classLabel>
<newAxiom>'Locally Advanced Unresectable Rectal Adenocarcinoma' EquivalentTo 'Metastatic Rectal Adenocarcinoma' and 'Unresectable Rectal Adenocarcinoma' and 'Locally Advanced Unresectable Colorectal Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162279</classIRI>
<classLabel>MET NM_000245.3:c.3688TC</classLabel>
<newAxiom>'MET NM_000245.3:c.3688TC' SubClassOf 'MET Gene Mutation'</newAxiom>
<newAxiom>'MET NM_000245.3:c.3688TC' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'MET NP_000236.2:p.Y1230H'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162278</classIRI>
<classLabel>MET NP_000236.2:p.S1236R</classLabel>
<newAxiom>'MET NP_000236.2:p.S1236R' SubClassOf 'MET Protein Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162277</classIRI>
<classLabel>MET NP_000236.2:p.M1250T</classLabel>
<newAxiom>'MET NP_000236.2:p.M1250T' SubClassOf 'MET Protein Variant'</newAxiom>
<newAxiom>'MET NP_000236.2:p.M1250T' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MET NM_000245.3:c.3749TC'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162276</classIRI>
<classLabel>MET NM_000245.3:c.3749TC</classLabel>
<newAxiom>'MET NM_000245.3:c.3749TC' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'MET NP_000236.2:p.M1250T'</newAxiom>
<newAxiom>'MET NM_000245.3:c.3749TC' SubClassOf 'MET Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162242</classIRI>
<classLabel>Stage IIIC Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IIIC Cervical Cancer FIGO 2018' EquivalentTo 'Stage III Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IIIC')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162241</classIRI>
<classLabel>Stage IIIB Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IIIB Cervical Cancer FIGO 2018' EquivalentTo 'Stage III Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IIIB')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162240</classIRI>
<classLabel>Stage IIIA Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IIIA Cervical Cancer FIGO 2018' EquivalentTo 'Stage III Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IIIA')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162246</classIRI>
<classLabel>Stage IVA Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IVA Cervical Cancer FIGO 2018' EquivalentTo 'Stage IV Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IVA')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162245</classIRI>
<classLabel>Stage IV Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IV Cervical Cancer FIGO 2018' EquivalentTo 'Cervical Cancer by FIGO Stage 2018' and ('Disease_Is_Stage' some 'FIGO Stage IV')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162244</classIRI>
<classLabel>Stage IIIC2 Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IIIC2 Cervical Cancer FIGO 2018' EquivalentTo 'Stage IIIC Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IIIC2')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162243</classIRI>
<classLabel>Stage IIIC1 Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IIIC1 Cervical Cancer FIGO 2018' EquivalentTo 'Stage IIIC Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IIIC1')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162249</classIRI>
<classLabel>Thousand Cells per Kilogram</classLabel>
<newAxiom>'Thousand Cells per Kilogram' SubClassOf 'Cells per Kilogram'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162248</classIRI>
<classLabel>Engineered Human Umbilical Vein Endothelial Cells AB-205</classLabel>
<newAxiom>'Engineered Human Umbilical Vein Endothelial Cells AB-205' SubClassOf 'Adoptive Cell Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162247</classIRI>
<classLabel>Stage IVB Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IVB Cervical Cancer FIGO 2018' EquivalentTo 'Stage IV Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IVB')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162260</classIRI>
<classLabel>Autologous Anti-HLA-A*02/AFP TCRm-expressing T-cells ET140202</classLabel>
<newAxiom>'Autologous Anti-HLA-A*02/AFP TCRm-expressing T-cells ET140202' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous Anti-HLA-A*02/AFP TCRm-expressing T-cells ET140202' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous Anti-HLA-A*02/AFP TCRm-expressing T-cells ET140202' SubClassOf 'T-cell Receptor-engineered T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162253</classIRI>
<classLabel>Recognition Hits</classLabel>
<newAxiom>'Recognition Hits' SubClassOf 'Entity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162252</classIRI>
<classLabel>Learning Slope</classLabel>
<newAxiom>'Learning Slope' SubClassOf 'Slope'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162251</classIRI>
<classLabel>Semantic Clustering</classLabel>
<newAxiom>'Semantic Clustering' SubClassOf 'Mental Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162250</classIRI>
<classLabel>Autologous mDC3 Vaccine</classLabel>
<newAxiom>'Autologous mDC3 Vaccine' SubClassOf 'Dendritic Cell Tumor Peptide Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162257</classIRI>
<classLabel>Resectable Colorectal Carcinoma</classLabel>
<newAxiom>'Resectable Colorectal Carcinoma' EquivalentTo 'Resectable Digestive System Carcinoma' and 'Colorectal Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162256</classIRI>
<classLabel>Hypermutated Colorectal Carcinoma</classLabel>
<newAxiom>'Hypermutated Colorectal Carcinoma' EquivalentTo 'Colorectal Carcinoma' and ('Disease_Has_Finding' some 'Hypermutated Sample') and ('Disease_May_Have_Molecular_Abnormality' some 'POLE Gene Mutation') and ('Disease_May_Have_Molecular_Abnormality' some 'POLD1 Gene Mutation') and ('Disease_May_Have_Molecular_Abnormality' some 'Mismatch Repair Gene Mutation')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162255</classIRI>
<classLabel>Metastatic Malignant Digestive System Neoplasm</classLabel>
<newAxiom>'Metastatic Malignant Digestive System Neoplasm' EquivalentTo 'Metastatic Malignant Neoplasm' and 'Malignant Digestive System Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Digestive System')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162254</classIRI>
<classLabel>Metastatic Malignant Female Reproductive System Neoplasm</classLabel>
<newAxiom>'Metastatic Malignant Female Reproductive System Neoplasm' EquivalentTo 'Metastatic Malignant Genitourinary System Neoplasm' and 'Malignant Female Reproductive System Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Female Reproductive System')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162259</classIRI>
<classLabel>Extraprostatic Extension</classLabel>
<newAxiom>'Extraprostatic Extension' SubClassOf 'Male Reproductive System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162258</classIRI>
<classLabel>Hypermutated Sample</classLabel>
<newAxiom>'Hypermutated Sample' SubClassOf 'Genetic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162220</classIRI>
<classLabel>Axitinib/Pembrolizumab Regimen</classLabel>
<newAxiom>'Axitinib/Pembrolizumab Regimen' SubClassOf 'Regimen Used to Treat Malignant Renal Neoplasm'</newAxiom>
<newAxiom>'Axitinib/Pembrolizumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Axitinib'</newAxiom>
<newAxiom>'Axitinib/Pembrolizumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Pembrolizumab'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162224</classIRI>
<classLabel>FIGO Stage IIA2</classLabel>
<newAxiom>'FIGO Stage IIA2' SubClassOf 'FIGO Stage IIA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162223</classIRI>
<classLabel>FIGO Stage IIA1</classLabel>
<newAxiom>'FIGO Stage IIA1' SubClassOf 'FIGO Stage IIA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162222</classIRI>
<classLabel>FIGO Stage IB3</classLabel>
<newAxiom>'FIGO Stage IB3' SubClassOf 'FIGO Stage IB'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162221</classIRI>
<classLabel>Metastatic Diagnosis</classLabel>
<newAxiom>'Metastatic Diagnosis' SubClassOf 'Other Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162228</classIRI>
<classLabel>Stage IA1 Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IA1 Cervical Cancer FIGO 2018' EquivalentTo 'Stage IA Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IA1')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162227</classIRI>
<classLabel>Stage IA Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IA Cervical Cancer FIGO 2018' EquivalentTo 'Stage I Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IA')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162226</classIRI>
<classLabel>Stage I Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage I Cervical Cancer FIGO 2018' EquivalentTo 'Cervical Cancer by FIGO Stage 2018' and ('Disease_Is_Stage' some 'FIGO Stage I')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162225</classIRI>
<classLabel>Cervical Cancer by FIGO Stage 2018</classLabel>
<newAxiom>'Cervical Cancer by FIGO Stage 2018' EquivalentTo 'Cervical Carcinoma' and ('Disease_Is_Stage' some 'FIGO Stage')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162229</classIRI>
<classLabel>Stage IA2 Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IA2 Cervical Cancer FIGO 2018' EquivalentTo 'Stage IA Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IA2')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162231</classIRI>
<classLabel>Stage IB1 Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IB1 Cervical Cancer FIGO 2018' EquivalentTo 'Stage IB Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IB1')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162230</classIRI>
<classLabel>Stage IB Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IB Cervical Cancer FIGO 2018' EquivalentTo 'Stage I Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IB')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162235</classIRI>
<classLabel>Stage IIA Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IIA Cervical Cancer FIGO 2018' EquivalentTo 'Stage II Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IIA')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162234</classIRI>
<classLabel>Stage II Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage II Cervical Cancer FIGO 2018' EquivalentTo 'Cervical Cancer by FIGO Stage 2018' and ('Disease_Is_Stage' some 'FIGO Stage II')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162233</classIRI>
<classLabel>Stage IB3 Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IB3 Cervical Cancer FIGO 2018' EquivalentTo 'Stage IB Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IB3')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162232</classIRI>
<classLabel>Stage IB2 Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IB2 Cervical Cancer FIGO 2018' EquivalentTo 'Stage IB Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IB2')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162239</classIRI>
<classLabel>Stage III Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage III Cervical Cancer FIGO 2018' EquivalentTo 'Cervical Cancer by FIGO Stage 2018' and ('Disease_Is_Stage' some 'FIGO Stage III')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162238</classIRI>
<classLabel>Stage IIB Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IIB Cervical Cancer FIGO 2018' EquivalentTo 'Stage II Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IIB')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162237</classIRI>
<classLabel>Stage IIA2 Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IIA2 Cervical Cancer FIGO 2018' EquivalentTo 'Stage IIA Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IIA2')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162236</classIRI>
<classLabel>Stage IIA1 Cervical Cancer FIGO 2018</classLabel>
<newAxiom>'Stage IIA1 Cervical Cancer FIGO 2018' EquivalentTo 'Stage IIA Cervical Cancer FIGO 2018' and ('Disease_Is_Stage' some 'FIGO Stage IIA1')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162202</classIRI>
<classLabel>Nervous System Elapsed Time</classLabel>
<newAxiom>'Nervous System Elapsed Time' SubClassOf 'Elapsed Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162201</classIRI>
<classLabel>Musculoskeletal Findings, Connective and Soft Tissue Findings Elapsed Time</classLabel>
<newAxiom>'Musculoskeletal Findings, Connective and Soft Tissue Findings Elapsed Time' SubClassOf 'Elapsed Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162200</classIRI>
<classLabel>Urinary System Findings Sponsor-Defined Identifier</classLabel>
<newAxiom>'Urinary System Findings Sponsor-Defined Identifier' SubClassOf 'Sponsor ID'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162206</classIRI>
<classLabel>Musculoskeletal Findings, Connective and Soft Tissue Findings Reference Identifier</classLabel>
<newAxiom>'Musculoskeletal Findings, Connective and Soft Tissue Findings Reference Identifier' SubClassOf 'Reference ID'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162205</classIRI>
<classLabel>Urinary System Findings Elapsed Time</classLabel>
<newAxiom>'Urinary System Findings Elapsed Time' SubClassOf 'Elapsed Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162204</classIRI>
<classLabel>Reproductive System Findings Elapsed Time</classLabel>
<newAxiom>'Reproductive System Findings Elapsed Time' SubClassOf 'Elapsed Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162203</classIRI>
<classLabel>Ophthalmic Examinations Elapsed Time</classLabel>
<newAxiom>'Ophthalmic Examinations Elapsed Time' SubClassOf 'Elapsed Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162209</classIRI>
<classLabel>Urinary System Findings Reference Identifier</classLabel>
<newAxiom>'Urinary System Findings Reference Identifier' SubClassOf 'Reference ID'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162208</classIRI>
<classLabel>Respiratory System Findings Reference Identifier</classLabel>
<newAxiom>'Respiratory System Findings Reference Identifier' SubClassOf 'Reference ID'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162207</classIRI>
<classLabel>Nervous System Reference Identifier</classLabel>
<newAxiom>'Nervous System Reference Identifier' SubClassOf 'Reference ID'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162213</classIRI>
<classLabel>Reproductive System Findings Time Point Reference</classLabel>
<newAxiom>'Reproductive System Findings Time Point Reference' SubClassOf 'Reference Time Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162212</classIRI>
<classLabel>Ophthalmic Examinations Time Point Reference</classLabel>
<newAxiom>'Ophthalmic Examinations Time Point Reference' SubClassOf 'Reference Time Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162211</classIRI>
<classLabel>Nervous System Time Point Reference</classLabel>
<newAxiom>'Nervous System Time Point Reference' SubClassOf 'Reference Time Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162210</classIRI>
<classLabel>Musculoskeletal Findings, Connective and Soft Tissue Findings Time Point Reference</classLabel>
<newAxiom>'Musculoskeletal Findings, Connective and Soft Tissue Findings Time Point Reference' SubClassOf 'Reference Time Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162217</classIRI>
<classLabel>Renal Parenchyma</classLabel>
<newAxiom>'Renal Parenchyma' SubClassOf 'Kidney Part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162216</classIRI>
<classLabel>Renal Calyx and Pelvis</classLabel>
<newAxiom>'Renal Calyx and Pelvis' SubClassOf 'Kidney Part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162214</classIRI>
<classLabel>Respiratory System Findings Reference Result in Original Units</classLabel>
<newAxiom>'Respiratory System Findings Reference Result in Original Units' SubClassOf 'Original Result Unit'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162219</classIRI>
<classLabel>Renal Sinus</classLabel>
<newAxiom>'Renal Sinus' SubClassOf 'Kidney Part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162218</classIRI>
<classLabel>Perinephric Fat</classLabel>
<newAxiom>'Perinephric Fat' SubClassOf 'Other Anatomic Concept'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>