<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
3
</numberChangedClasses>
<numberNewClasses>
46
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C154221</classIRI>
<classLabel>Unresectable Gastric Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Unresectable Gastric Adenocarcinoma&apos; EquivalentTo &apos;Unresectable Digestive System Adenocarcinoma&apos; and &apos;Gastric Adenocarcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Unresectable Gastric Adenocarcinoma&apos; EquivalentTo &apos;Unresectable Digestive System Adenocarcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159775 and &apos;Gastric Adenocarcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148085</classIRI>
<classLabel>BRCA2 Gene Mutation Negative</classLabel>
<deletedAxiom>&apos;BRCA2 Gene Mutation Negative&apos; SubClassOf &apos;Negative Test Result&apos;</deletedAxiom>
<deletedAxiom>&apos;BRCA2 Gene Mutation Negative&apos; SubClassOf &apos;Genetic Finding&apos;</deletedAxiom>
<newAxiom>&apos;BRCA2 Gene Mutation Negative&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159778</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148084</classIRI>
<classLabel>BRCA1 Gene Mutation Negative</classLabel>
<deletedAxiom>&apos;BRCA1 Gene Mutation Negative&apos; SubClassOf &apos;Negative Test Result&apos;</deletedAxiom>
<deletedAxiom>&apos;BRCA1 Gene Mutation Negative&apos; SubClassOf &apos;Genetic Finding&apos;</deletedAxiom>
<newAxiom>&apos;BRCA1 Gene Mutation Negative&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159778</newAxiom>
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<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159806</classIRI>
<classLabel>IMWG Complete Response</classLabel>
<newAxiom>'IMWG Complete Response' SubClassOf 'International Myeloma Working Group Standard Response Criteria'</newAxiom>
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<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159805</classIRI>
<classLabel>IMWG Stringent Complete Response</classLabel>
<newAxiom>'IMWG Stringent Complete Response' SubClassOf 'International Myeloma Working Group Standard Response Criteria'</newAxiom>
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<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159808</classIRI>
<classLabel>IMWG Partial Response</classLabel>
<newAxiom>'IMWG Partial Response' SubClassOf 'International Myeloma Working Group Standard Response Criteria'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159807</classIRI>
<classLabel>IMWG Very Good Partial Response</classLabel>
<newAxiom>'IMWG Very Good Partial Response' SubClassOf 'International Myeloma Working Group Standard Response Criteria'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159809</classIRI>
<classLabel>IMWG Minimal Response</classLabel>
<newAxiom>'IMWG Minimal Response' SubClassOf 'International Myeloma Working Group Standard Response Criteria'</newAxiom>
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<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159800</classIRI>
<classLabel>IMWG Sustained MRD-negative</classLabel>
<newAxiom>'IMWG Sustained MRD-negative' SubClassOf 'International Myeloma Working Group Minimal Residual Disease Criteria'</newAxiom>
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<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159802</classIRI>
<classLabel>IMWG Sequencing MRD-negative</classLabel>
<newAxiom>'IMWG Sequencing MRD-negative' SubClassOf 'International Myeloma Working Group Minimal Residual Disease Criteria'</newAxiom>
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<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159801</classIRI>
<classLabel>IMWG Flow MRD-negative</classLabel>
<newAxiom>'IMWG Flow MRD-negative' SubClassOf 'International Myeloma Working Group Minimal Residual Disease Criteria'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159804</classIRI>
<classLabel>International Myeloma Working Group Standard Response Criteria</classLabel>
<newAxiom>'International Myeloma Working Group Standard Response Criteria' SubClassOf 'Tumor Response Criterion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159803</classIRI>
<classLabel>IMWG Imaging plus MRD-negative</classLabel>
<newAxiom>'IMWG Imaging plus MRD-negative' SubClassOf 'International Myeloma Working Group Minimal Residual Disease Criteria'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159817</classIRI>
<classLabel>TGFbeta Receptor Ectodomain-IgG Fc Fusion Protein AVID200</classLabel>
<newAxiom>'TGFbeta Receptor Ectodomain-IgG Fc Fusion Protein AVID200' SubClassOf 'Antineoplastic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159816</classIRI>
<classLabel>Performance Status Scale Timing Not Applicable</classLabel>
<newAxiom>'Performance Status Scale Timing Not Applicable' SubClassOf 'CPTAC Questions'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159819</classIRI>
<classLabel>HPV-None</classLabel>
<newAxiom>'HPV-None' SubClassOf 'CPTAC Questions'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159818</classIRI>
<classLabel>HPV-Other Type</classLabel>
<newAxiom>'HPV-Other Type' SubClassOf 'CPTAC Questions'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159811</classIRI>
<classLabel>IMWG Progressive Disease</classLabel>
<newAxiom>'IMWG Progressive Disease' SubClassOf 'International Myeloma Working Group Standard Response Criteria'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159810</classIRI>
<classLabel>IMWG Stable Disease</classLabel>
<newAxiom>'IMWG Stable Disease' SubClassOf 'International Myeloma Working Group Standard Response Criteria'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159813</classIRI>
<classLabel>Outcome Measure of Success of Outcome at Form Completion Not Applicable</classLabel>
<newAxiom>'Outcome Measure of Success of Outcome at Form Completion Not Applicable' SubClassOf 'CPTAC Questions'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159812</classIRI>
<classLabel>Outcome Measure of Success at Completion of Initial Treatment Course Not Applicable</classLabel>
<newAxiom>'Outcome Measure of Success at Completion of Initial Treatment Course Not Applicable' SubClassOf 'CPTAC Questions'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159815</classIRI>
<classLabel>Performance Status Scale Timing Unknown</classLabel>
<newAxiom>'Performance Status Scale Timing Unknown' SubClassOf 'CPTAC Questions'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159814</classIRI>
<classLabel>Outcome Measure of Success at Form Completion Unknown</classLabel>
<newAxiom>'Outcome Measure of Success at Form Completion Unknown' SubClassOf 'CPTAC Questions'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159820</classIRI>
<classLabel>Other HPV Typing Method</classLabel>
<newAxiom>'Other HPV Typing Method' SubClassOf 'CPTAC Questions'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159821</classIRI>
<classLabel>Healthcare Device Direct Feed Reporting</classLabel>
<newAxiom>'Healthcare Device Direct Feed Reporting' SubClassOf 'Reporting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159798</classIRI>
<classLabel>Tasadenoturev-infected Allogeneic Bone Marrow-derived Mesenchymal Stem Cells</classLabel>
<newAxiom>'Tasadenoturev-infected Allogeneic Bone Marrow-derived Mesenchymal Stem Cells' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
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<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159799</classIRI>
<classLabel>International Myeloma Working Group Minimal Residual Disease Criteria</classLabel>
<newAxiom>'International Myeloma Working Group Minimal Residual Disease Criteria' SubClassOf 'Tumor Response Criterion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159776</classIRI>
<classLabel>Continuous Glucose Monitoring System</classLabel>
<newAxiom>'Continuous Glucose Monitoring System' SubClassOf 'Diagnostic, Therapeutic, or Research Equipment'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159775</classIRI>
<classLabel>Unresectable Gastric Carcinoma</classLabel>
<newAxiom>'Unresectable Gastric Carcinoma' EquivalentTo 'Unresectable Digestive System Carcinoma' and 'Gastric Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159778</classIRI>
<classLabel>Fanconi Anemia Complementation Group Gene Mutation Negative</classLabel>
<newAxiom>'Fanconi Anemia Complementation Group Gene Mutation Negative' SubClassOf 'Genetic Finding'</newAxiom>
<newAxiom>'Fanconi Anemia Complementation Group Gene Mutation Negative' SubClassOf 'Negative Test Result'</newAxiom>
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<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159777</classIRI>
<classLabel>PSA Level Twenty to One Hundred Fifty</classLabel>
<newAxiom>'PSA Level Twenty to One Hundred Fifty' SubClassOf 'PSA Level Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159779</classIRI>
<classLabel>PALB2 Gene Mutation Negative</classLabel>
<newAxiom>'PALB2 Gene Mutation Negative' SubClassOf 'Fanconi Anemia Complementation Group Gene Mutation Negative'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159781</classIRI>
<classLabel>FANCL Gene Mutation Negative</classLabel>
<newAxiom>'FANCL Gene Mutation Negative' SubClassOf 'Fanconi Anemia Complementation Group Gene Mutation Negative'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159780</classIRI>
<classLabel>BRIP1 Gene Mutation Negative</classLabel>
<newAxiom>'BRIP1 Gene Mutation Negative' SubClassOf 'Fanconi Anemia Complementation Group Gene Mutation Negative'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159783</classIRI>
<classLabel>ATM Gene Mutation Negative</classLabel>
<newAxiom>'ATM Gene Mutation Negative' SubClassOf 'Genetic Finding'</newAxiom>
<newAxiom>'ATM Gene Mutation Negative' SubClassOf 'Negative Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159782</classIRI>
<classLabel>RAD51 Gene Mutation Negative</classLabel>
<newAxiom>'RAD51 Gene Mutation Negative' SubClassOf 'Fanconi Anemia Complementation Group Gene Mutation Negative'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159785</classIRI>
<classLabel>CST1 wt Allele</classLabel>
<newAxiom>'CST1 wt Allele' SubClassOf 'CST1 Gene'</newAxiom>
<newAxiom>'CST1 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Salivary Secretion Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159784</classIRI>
<classLabel>CST1 Gene</classLabel>
<newAxiom>'CST1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Gustation'</newAxiom>
<newAxiom>'CST1 Gene' SubClassOf 'Cystatin Family Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159787</classIRI>
<classLabel>Checkpoint Inhibitor Relapsed Tumor</classLabel>
<newAxiom>'Checkpoint Inhibitor Relapsed Tumor' SubClassOf 'Relapse of Prior Malignancy'</newAxiom>
</newClass>
<newClass>
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<classLabel>Cystatin-SN</classLabel>
<newAxiom>'Cystatin-SN' EquivalentTo 'Enzyme Inhibitor Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Salivary Secretion Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Saliva') and ('Gene_Product_Has_Associated_Anatomy' some 'Urine') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Associated_Anatomy' some 'Seminal Fluid') and ('Gene_Product_Has_Associated_Anatomy' some 'Tear') and ('Gene_Product_Expressed_In_Tissue' some 'Submandibular Gland') and ('Gene_Product_Expressed_In_Tissue' some 'Sublingual Salivary Gland') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Regulation of Proteolysis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Gustation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Enzyme Inhibition') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Degradation Inhibition') and ('Gene_Product_Encoded_By_Gene' some 'CST1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159789</classIRI>
<classLabel>CST2 wt Allele</classLabel>
<newAxiom>'CST2 wt Allele' SubClassOf 'CST2 Gene'</newAxiom>
<newAxiom>'CST2 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Salivary Secretion Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159788</classIRI>
<classLabel>CST2 Gene</classLabel>
<newAxiom>'CST2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Gustation'</newAxiom>
<newAxiom>'CST2 Gene' SubClassOf 'Cystatin Family Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159790</classIRI>
<classLabel>Cystatin-SA</classLabel>
<newAxiom>'Cystatin-SA' EquivalentTo 'Enzyme Inhibitor Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Salivary Secretion Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Saliva') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Expressed_In_Tissue' some 'Submandibular Gland') and ('Gene_Product_Expressed_In_Tissue' some 'Parotid Gland') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Regulation of Proteolysis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Gustation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Enzyme Inhibition') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Degradation Inhibition') and ('Gene_Product_Encoded_By_Gene' some 'CST2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159792</classIRI>
<classLabel>CST4 wt Allele</classLabel>
<newAxiom>'CST4 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Salivary Secretion Pathway'</newAxiom>
<newAxiom>'CST4 wt Allele' SubClassOf 'CST4 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159791</classIRI>
<classLabel>CST4 Gene</classLabel>
<newAxiom>'CST4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Gustation'</newAxiom>
<newAxiom>'CST4 Gene' SubClassOf 'Cystatin Family Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159794</classIRI>
<classLabel>CST5 Gene</classLabel>
<newAxiom>'CST5 Gene' SubClassOf 'Cystatin Family Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159793</classIRI>
<classLabel>Cystatin-S</classLabel>
<newAxiom>'Cystatin-S' EquivalentTo 'Enzyme Inhibitor Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Salivary Secretion Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Saliva') and ('Gene_Product_Has_Associated_Anatomy' some 'Urine') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Associated_Anatomy' some 'Seminal Fluid') and ('Gene_Product_Has_Associated_Anatomy' some 'Tear') and ('Gene_Product_Expressed_In_Tissue' some 'Submandibular Gland') and ('Gene_Product_Expressed_In_Tissue' some 'Sublingual Salivary Gland') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Regulation of Proteolysis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Gustation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Enzyme Inhibition') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Degradation Inhibition') and ('Gene_Product_Encoded_By_Gene' some 'CST4 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159796</classIRI>
<classLabel>Cystatin-D</classLabel>
<newAxiom>'Cystatin-D' EquivalentTo 'Enzyme Inhibitor Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Salivary Secretion Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Saliva') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Expressed_In_Tissue' some 'Submandibular Gland') and ('Gene_Product_Expressed_In_Tissue' some 'Sublingual Salivary Gland') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Regulation of Proteolysis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Enzyme Inhibition') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Degradation Inhibition') and ('Gene_Product_Encoded_By_Gene' some 'CST5 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159795</classIRI>
<classLabel>CST5 wt Allele</classLabel>
<newAxiom>'CST5 wt Allele' SubClassOf 'CST5 Gene'</newAxiom>
<newAxiom>'CST5 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Salivary Secretion Pathway'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>