<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
335
</numberChangedClasses>
<numberNewClasses>
574
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28302</classIRI>
<classLabel>Advanced Adult Hepatocellular Carcinoma</classLabel>
<deletedAxiom>&apos;Advanced Adult Hepatocellular Carcinoma&apos; EquivalentTo &apos;Advanced Carcinoma&apos; and &apos;Metastatic Hepatocellular Carcinoma&apos; and &apos;Adult Hepatocellular Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Adult Hepatocellular Carcinoma&apos; EquivalentTo &apos;Metastatic Hepatocellular Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156746 and &apos;Adult Hepatocellular Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C119676</classIRI>
<classLabel>D-Bifunctional Protein Deficiency</classLabel>
<newAxiom>&apos;D-Bifunctional Protein Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;HSD17B4 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C119677</classIRI>
<classLabel>Alpha-Methylacyl-CoA Racemase Deficiency</classLabel>
<newAxiom>&apos;Alpha-Methylacyl-CoA Racemase Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;AMACR Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C119678</classIRI>
<classLabel>Mitochondrial Neurogastrointestinal Encephalopathy</classLabel>
<newAxiom>&apos;Mitochondrial Neurogastrointestinal Encephalopathy&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;TYMP Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3335</classIRI>
<classLabel>Rothmund-Thomson Syndrome</classLabel>
<newAxiom>&apos;Rothmund-Thomson Syndrome&apos; SubClassOf &apos;Syndrome&apos;</newAxiom>
<newAxiom>&apos;Rothmund-Thomson Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;RECQL4 Gene&apos;</newAxiom>
<newAxiom>&apos;Rothmund-Thomson Syndrome&apos; SubClassOf &apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;RECQL4 Gene Mutation&apos;</newAxiom>
<newAxiom>&apos;Rothmund-Thomson Syndrome&apos; SubClassOf &apos;Genodermatosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C53669</classIRI>
<classLabel>NNI Project Component Areas</classLabel>
<deletedAxiom>&apos;NNI Project Component Areas&apos; SubClassOf &apos;NCI Administrative Concept&apos;</deletedAxiom>
<newAxiom>&apos;NNI Project Component Areas&apos; SubClassOf &apos;Component of the National Cancer Institute&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3161</classIRI>
<classLabel>Leukemia</classLabel>
<deletedAxiom>&apos;Leukemia&apos; EquivalentTo &apos;Hematopoietic and Lymphoid Cell Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Marrow&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Leukemic Cell&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Solid Growth Pattern&apos;)</deletedAxiom>
<newAxiom>&apos;Leukemia&apos; EquivalentTo &apos;Hematopoietic and Lymphoid Cell Neoplasm&apos; and &apos;Malignant Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Marrow&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Leukemic Cell&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Solid Growth Pattern&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3040</classIRI>
<classLabel>Fibrodysplasia Ossificans Progressiva</classLabel>
<deletedAxiom>&apos;Fibrodysplasia Ossificans Progressiva&apos; EquivalentTo &apos;Genetic Disorder&apos; and &apos;Rare Non-Neoplastic Disorder&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Ossification&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Hallux Valgus&apos;)</deletedAxiom>
<newAxiom>&apos;Fibrodysplasia Ossificans Progressiva&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ACVR1 Gene&apos;</newAxiom>
<newAxiom>&apos;Fibrodysplasia Ossificans Progressiva&apos; SubClassOf &apos;Disease_Has_Associated_Disease&apos; some &apos;Hallux Valgus&apos;</newAxiom>
<newAxiom>&apos;Fibrodysplasia Ossificans Progressiva&apos; SubClassOf &apos;Genetic Disorder&apos;</newAxiom>
<newAxiom>&apos;Fibrodysplasia Ossificans Progressiva&apos; SubClassOf &apos;Rare Non-Neoplastic Disorder&apos;</newAxiom>
<newAxiom>&apos;Fibrodysplasia Ossificans Progressiva&apos; SubClassOf &apos;Disease_Has_Finding&apos; some &apos;Ossification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3678</classIRI>
<classLabel>Salivary Gland Basal Cell Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Salivary Gland Basal Cell Adenocarcinoma&apos; EquivalentTo &apos;Malignant Basal Cell Neoplasm&apos; and &apos;Salivary Gland Adenocarcinoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Non-Cutaneous Basaloid Cell&apos;)</deletedAxiom>
<newAxiom>&apos;Salivary Gland Basal Cell Adenocarcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156767 and &apos;Salivary Gland Adenocarcinoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Non-Cutaneous Basaloid Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3674</classIRI>
<classLabel>Reproductive System Neoplasm</classLabel>
<deletedAxiom>&apos;Reproductive System Neoplasm&apos; EquivalentTo &apos;Neoplasm by Site&apos; and &apos;Reproductive System Disorder&apos;</deletedAxiom>
<newAxiom>&apos;Reproductive System Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156482 and &apos;Reproductive System Disorder&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3537</classIRI>
<classLabel>Malignant Retroperitoneal Neoplasm</classLabel>
<deletedAxiom>&apos;Malignant Retroperitoneal Neoplasm&apos; EquivalentTo &apos;Retroperitoneal Neoplasm&apos; and &apos;Malignant Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Malignant Retroperitoneal Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156711 and &apos;Retroperitoneal Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3538</classIRI>
<classLabel>Malignant Peritoneal Neoplasm</classLabel>
<deletedAxiom>&apos;Malignant Peritoneal Neoplasm&apos; EquivalentTo &apos;Peritoneal Neoplasm&apos; and &apos;Malignant Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Malignant Peritoneal Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156711 and &apos;Peritoneal Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3430</classIRI>
<classLabel>Urinary System Disorder</classLabel>
<deletedAxiom>&apos;Urinary System Disorder&apos; SubClassOf &apos;Disorder by Site&apos;</deletedAxiom>
<newAxiom>&apos;Urinary System Disorder&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156660</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3431</classIRI>
<classLabel>Urinary System Neoplasm</classLabel>
<deletedAxiom>&apos;Urinary System Neoplasm&apos; EquivalentTo &apos;Neoplasm by Site&apos; and &apos;Urinary System Disorder&apos;</deletedAxiom>
<newAxiom>&apos;Urinary System Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156482 and &apos;Urinary System Disorder&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48283</classIRI>
<classLabel>Parathyroid Gland Lipoadenoma</classLabel>
<deletedAxiom>&apos;Parathyroid Gland Lipoadenoma&apos; EquivalentTo &apos;Parathyroid Gland Adenoma&apos; and &apos;Lipoadenoma&apos; and (&apos;Disease_Excludes_Finding&apos; some &apos;Tumor Vascular Invasion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Capsular Invasion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Perineural Invasion&apos;)</deletedAxiom>
<newAxiom>&apos;Parathyroid Gland Lipoadenoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156757 and &apos;Lipoadenoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48320</classIRI>
<classLabel>Adrenal Gland Angiosarcoma</classLabel>
<deletedAxiom>&apos;Adrenal Gland Angiosarcoma&apos; EquivalentTo &apos;Soft Tissue Angiosarcoma&apos; and &apos;Malignant Adrenal Gland Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Adrenal Gland&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Adrenal Gland Tissue&apos;)</deletedAxiom>
<newAxiom>&apos;Adrenal Gland Angiosarcoma&apos; EquivalentTo &apos;Soft Tissue Angiosarcoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156956</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48319</classIRI>
<classLabel>Adrenal Gland Adenomatoid Tumor</classLabel>
<deletedAxiom>&apos;Adrenal Gland Adenomatoid Tumor&apos; EquivalentTo &apos;Benign Adrenal Gland Neoplasm&apos; and &apos;Adenomatoid Tumor&apos;</deletedAxiom>
<newAxiom>&apos;Adrenal Gland Adenomatoid Tumor&apos; EquivalentTo &apos;Adenomatoid Tumor&apos; and &apos;Benign Adrenal Cortex Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124845</classIRI>
<classLabel>Hyperglycerolemia</classLabel>
<newAxiom>&apos;Hyperglycerolemia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GK Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48449</classIRI>
<classLabel>Cortisol-Producing Adrenal Cortex Adenoma</classLabel>
<deletedAxiom>&apos;Cortisol-Producing Adrenal Cortex Adenoma&apos; EquivalentTo &apos;Adrenal Cortex Adenoma&apos; and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Cushing Syndrome&apos;)</deletedAxiom>
<newAxiom>&apos;Cortisol-Producing Adrenal Cortex Adenoma&apos; EquivalentTo &apos;Adrenal Cortex Adenoma&apos; and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Cushing Syndrome&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;PRKACA Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156938)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48451</classIRI>
<classLabel>Aldosterone-Producing Adrenal Cortex Adenoma</classLabel>
<deletedAxiom>&apos;Aldosterone-Producing Adrenal Cortex Adenoma&apos; EquivalentTo &apos;Adrenal Cortex Adenoma&apos; and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Conn Syndrome&apos;)</deletedAxiom>
<newAxiom>&apos;Aldosterone-Producing Adrenal Cortex Adenoma&apos; EquivalentTo &apos;Adrenal Cortex Adenoma&apos; and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Conn Syndrome&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;ATP1A1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;ATP2B3 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CACNA1D Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;KCNJ5 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156934) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156935) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156936) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156937)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48458</classIRI>
<classLabel>Non-Functioning Adrenal Cortex Adenoma</classLabel>
<deletedAxiom>&apos;Non-Functioning Adrenal Cortex Adenoma&apos; EquivalentTo &apos;Adrenal Cortex Adenoma&apos; and &apos;Non-Functioning Endocrine Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Absence of a Hormonal Syndrome&apos;)</deletedAxiom>
<newAxiom>&apos;Non-Functioning Adrenal Cortex Adenoma&apos; EquivalentTo &apos;Adrenal Cortex Adenoma&apos; and &apos;Non-Functioning Endocrine Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Absence of a Hormonal Syndrome&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CTNNB1 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CTNNB1 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3968</classIRI>
<classLabel>Xeroderma Pigmentosum, Complementation Group F</classLabel>
<newAxiom>&apos;Xeroderma Pigmentosum, Complementation Group F&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ERCC4 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3969</classIRI>
<classLabel>Xeroderma Pigmentosum, Complementation Group G</classLabel>
<newAxiom>&apos;Xeroderma Pigmentosum, Complementation Group G&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ERCC5 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3965</classIRI>
<classLabel>Xeroderma Pigmentosum, Complementation Group A</classLabel>
<newAxiom>&apos;Xeroderma Pigmentosum, Complementation Group A&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;XPA Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3966</classIRI>
<classLabel>Xeroderma Pigmentosum, Complementation Group B</classLabel>
<newAxiom>&apos;Xeroderma Pigmentosum, Complementation Group B&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ERCC3 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3967</classIRI>
<classLabel>Xeroderma Pigmentosum, Complementation Group D</classLabel>
<newAxiom>&apos;Xeroderma Pigmentosum, Complementation Group D&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ERCC2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3916</classIRI>
<classLabel>Parathyroid Gland Adenoma</classLabel>
<deletedAxiom>&apos;Parathyroid Gland Adenoma&apos; EquivalentTo &apos;Adenoma&apos; and &apos;Benign Parathyroid Gland Neoplasm&apos; and &apos;Benign Endocrine Neoplasm&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Parathyroid Gland Epithelial Tissue&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Parathyroid Gland Parenchymal Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Trabecular Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Acinar Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Encapsulated Mass&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Solid Growth Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Follicular Structures Present&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Primary Hyperparathyroidism&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CCND1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MEN1 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Aneuploidy&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;MEN1 Gene Inactivation&apos;)</deletedAxiom>
<newAxiom>&apos;Parathyroid Gland Adenoma&apos; EquivalentTo &apos;Adenoma&apos; and &apos;Parathyroid Gland Neoplasm&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Parathyroid Gland Epithelial Tissue&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Parathyroid Gland Parenchymal Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Trabecular Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Acinar Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Encapsulated Mass&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Solid Growth Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Follicular Structures Present&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Primary Hyperparathyroidism&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Tumor Vascular Invasion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Capsular Invasion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Perineural Invasion&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CCND1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MEN1 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Aneuploidy&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;MEN1 Gene Inactivation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3844</classIRI>
<classLabel>Gallbladder Carcinoma</classLabel>
<deletedAxiom>&apos;Gallbladder Carcinoma&apos; EquivalentTo &apos;Infrequent Neoplasm&apos; and &apos;Malignant Gallbladder Neoplasm&apos; and &apos;Digestive System Carcinoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Gallbladder&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Gallbladder Epithelium&apos;)</deletedAxiom>
<newAxiom>&apos;Gallbladder Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156781 and &apos;Infrequent Neoplasm&apos; and &apos;Malignant Gallbladder Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Gallbladder&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Gallbladder Epithelium&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3816</classIRI>
<classLabel>Type II Achondrogenesis</classLabel>
<newAxiom>&apos;Type II Achondrogenesis&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;COL2A1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125594</classIRI>
<classLabel>Kniest Dysplasia</classLabel>
<newAxiom>&apos;Kniest Dysplasia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;COL2A1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125592</classIRI>
<classLabel>Holt-Oram Syndrome</classLabel>
<newAxiom>&apos;Holt-Oram Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;TBX5 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150601</classIRI>
<classLabel>Citrullinemia Type I</classLabel>
<newAxiom>&apos;Citrullinemia Type I&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ASS1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150608</classIRI>
<classLabel>Minicore Myopathy with External Ophthalmoplegia</classLabel>
<newAxiom>&apos;Minicore Myopathy with External Ophthalmoplegia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;RYR1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125693</classIRI>
<classLabel>Atransferrinemia</classLabel>
<newAxiom>&apos;Atransferrinemia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;TF Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125385</classIRI>
<classLabel>Paroxysmal Extreme Pain Disorder</classLabel>
<newAxiom>&apos;Paroxysmal Extreme Pain Disorder&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SCN9A Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125386</classIRI>
<classLabel>Indifference to Pain, Congenital, Autosomal Recessive</classLabel>
<newAxiom>&apos;Indifference to Pain, Congenital, Autosomal Recessive&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SCN9A Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125383</classIRI>
<classLabel>Primary Erythromelalgia</classLabel>
<newAxiom>&apos;Primary Erythromelalgia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SCN9A Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34842</classIRI>
<classLabel>Alport Syndrome</classLabel>
<newAxiom>&apos;Alport Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;COL4A5 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C93185</classIRI>
<classLabel>Anatomist</classLabel>
<deletedAxiom>&apos;Anatomist&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Anatomist&apos; SubClassOf &apos;Medical Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34951</classIRI>
<classLabel>Progeria</classLabel>
<newAxiom>&apos;Progeria&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;LMNA Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C130983</classIRI>
<classLabel>Barakat Syndrome</classLabel>
<newAxiom>&apos;Barakat Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GATA3 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20987</classIRI>
<classLabel>CTNNB1 Gene</classLabel>
<newAxiom>&apos;CTNNB1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Non-Functioning Adrenal Cortex Adenoma&apos;</newAxiom>
<newAxiom>&apos;CTNNB1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Adrenal Cortex Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118434</classIRI>
<classLabel>Albright&apos;s Hereditary Osteodystrophy</classLabel>
<newAxiom>&apos;Albright&apos;s Hereditary Osteodystrophy&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GNAS Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118437</classIRI>
<classLabel>Glycogen Storage Disease Type VII</classLabel>
<newAxiom>&apos;Glycogen Storage Disease Type VII&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;PFKM Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29719</classIRI>
<classLabel>Tobacco Smoking History</classLabel>
<deletedAxiom>&apos;Tobacco Smoking History&apos; SubClassOf &apos;Personal Medical History&apos;</deletedAxiom>
<newAxiom>&apos;Tobacco Smoking History&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156825</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2041</classIRI>
<classLabel>Radicicol Derivative KF58333</classLabel>
<deletedAxiom>&apos;Radicicol Derivative KF58333&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Radicicol Derivative KF58333&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40553</classIRI>
<classLabel>Tooth and Nail Syndrome</classLabel>
<newAxiom>&apos;Tooth and Nail Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MSX1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74061</classIRI>
<classLabel>Crizotinib</classLabel>
<newAxiom>&apos;Crizotinib&apos; SubClassOf &apos;c-Met Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74040</classIRI>
<classLabel>Hsp90 Inhibitor SNX-5542 Mesylate</classLabel>
<deletedAxiom>&apos;Hsp90 Inhibitor SNX-5542 Mesylate&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Hsp90 Inhibitor SNX-5542 Mesylate&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15748</classIRI>
<classLabel>Total Nodal Irradiation</classLabel>
<deletedAxiom>&apos;Total Nodal Irradiation&apos; SubClassOf &apos;Prior Extensive Radiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15756</classIRI>
<classLabel>Single Agent Systemic Chemotherapy</classLabel>
<deletedAxiom>&apos;Single Agent Systemic Chemotherapy&apos; SubClassOf &apos;Prior Chemotherapy&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123813</classIRI>
<classLabel>Beare-Stevenson Cutis Gyrata Syndrome</classLabel>
<newAxiom>&apos;Beare-Stevenson Cutis Gyrata Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;FGFR2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123814</classIRI>
<classLabel>Jackson-Weiss Syndrome</classLabel>
<newAxiom>&apos;Jackson-Weiss Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;FGFR2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123815</classIRI>
<classLabel>Myhre Syndrome</classLabel>
<newAxiom>&apos;Myhre Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SMAD4 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40846</classIRI>
<classLabel>Negative Regulation of Lymphocyte Activation</classLabel>
<newAxiom>&apos;Negative Regulation of Lymphocyte Activation&apos; SubClassOf &apos;Negative Regulation of Immune Cell Activation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123667</classIRI>
<classLabel>Montreal Cognitive Assessment Functional Test</classLabel>
<newAxiom>&apos;Montreal Cognitive Assessment Functional Test&apos; SubClassOf &apos;Cognitive Assessment&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123437</classIRI>
<classLabel>Multicentric Osteolysis, Nodulosis, and Arthropathy</classLabel>
<newAxiom>&apos;Multicentric Osteolysis, Nodulosis, and Arthropathy&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MMP2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123417</classIRI>
<classLabel>Mandibuloacral Dysplasia with Type A Lipodystrophy</classLabel>
<newAxiom>&apos;Mandibuloacral Dysplasia with Type A Lipodystrophy&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;LMNA Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35139</classIRI>
<classLabel>Alagille Syndrome</classLabel>
<newAxiom>&apos;Alagille Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;JAG1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35257</classIRI>
<classLabel>Alper Syndrome</classLabel>
<newAxiom>&apos;Alper Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;POLG Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74912</classIRI>
<classLabel>Acid Urate Crystal Measurement</classLabel>
<deletedAxiom>&apos;Acid Urate Crystal Measurement&apos; SubClassOf &apos;Crystal Growth Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Acid Urate Crystal Measurement&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74986</classIRI>
<classLabel>Van der Woude Syndrome</classLabel>
<newAxiom>&apos;Van der Woude Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;IRF6 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74987</classIRI>
<classLabel>Feingold Syndrome</classLabel>
<newAxiom>&apos;Feingold Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MYCN Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C60312</classIRI>
<classLabel>Serum Prostate Specific Antigen Increased</classLabel>
<newAxiom>&apos;Serum Prostate Specific Antigen Increased&apos; SubClassOf &apos;PSA Progression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74995</classIRI>
<classLabel>Holoprosencephaly Type 2</classLabel>
<newAxiom>&apos;Holoprosencephaly Type 2&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SIX3 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74997</classIRI>
<classLabel>Joubert Syndrome Type 4</classLabel>
<newAxiom>&apos;Joubert Syndrome Type 4&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;NPHP1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74998</classIRI>
<classLabel>Familial Juvenile Nephronophthisis</classLabel>
<newAxiom>&apos;Familial Juvenile Nephronophthisis&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;NPHP1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74999</classIRI>
<classLabel>Mowat-Wilson Syndrome</classLabel>
<newAxiom>&apos;Mowat-Wilson Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ZEB2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2921</classIRI>
<classLabel>Skin Basal Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Skin Basal Cell Carcinoma&apos; EquivalentTo &apos;Skin Carcinoma&apos; and &apos;Malignant Basal Cell Neoplasm&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Basal Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Cutaneous Basaloid Cell&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;PTCH1 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PTCH Gene Inactivation&apos;)</deletedAxiom>
<newAxiom>&apos;Skin Basal Cell Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156767 and &apos;Skin Carcinoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Basal Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Cutaneous Basaloid Cell&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;PTCH1 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PTCH Gene Inactivation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C60783</classIRI>
<classLabel>Malignant Cutaneous Basaloid Cell</classLabel>
<deletedAxiom>&apos;Malignant Cutaneous Basaloid Cell&apos; SubClassOf &apos;Malignant Basaloid Cell&apos;</deletedAxiom>
<newAxiom>&apos;Malignant Cutaneous Basaloid Cell&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156768</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C69139</classIRI>
<classLabel>Hsp90 Antagonist KW-2478</classLabel>
<deletedAxiom>&apos;Hsp90 Antagonist KW-2478&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Hsp90 Antagonist KW-2478&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35875</classIRI>
<classLabel>Bronchogenic Carcinoma</classLabel>
<deletedAxiom>&apos;Bronchogenic Carcinoma&apos; EquivalentTo &apos;Lung Carcinoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bronchus&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Bronchial Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Bronchial Epithelial Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Dyspnea&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemoptysis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cough&apos;)</deletedAxiom>
<newAxiom>&apos;Bronchogenic Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156885 and &apos;Lung Carcinoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bronchus&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Bronchial Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Bronchial Epithelial Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Dyspnea&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemoptysis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cough&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118845</classIRI>
<classLabel>Otopalatodigital Syndrome Type 1</classLabel>
<newAxiom>&apos;Otopalatodigital Syndrome Type 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;FLNA Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118846</classIRI>
<classLabel>Miyoshi Muscular Dystrophy 1</classLabel>
<newAxiom>&apos;Miyoshi Muscular Dystrophy 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;DYSF Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118847</classIRI>
<classLabel>Spinal Muscular Atrophy Type 3</classLabel>
<newAxiom>&apos;Spinal Muscular Atrophy Type 3&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SMN1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80460</classIRI>
<classLabel>Biventricular Pacemaker</classLabel>
<deletedAxiom>&apos;Biventricular Pacemaker&apos; SubClassOf &apos;Medical Device&apos;</deletedAxiom>
<newAxiom>&apos;Biventricular Pacemaker&apos; SubClassOf &apos;Permanent Cardiac Pacemaker&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80458</classIRI>
<classLabel>Single Chamber Pacemaker</classLabel>
<deletedAxiom>&apos;Single Chamber Pacemaker&apos; SubClassOf &apos;Medical Device&apos;</deletedAxiom>
<newAxiom>&apos;Single Chamber Pacemaker&apos; SubClassOf &apos;Cardiac Pacemaker&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80459</classIRI>
<classLabel>Dual Chamber Pacemaker</classLabel>
<deletedAxiom>&apos;Dual Chamber Pacemaker&apos; SubClassOf &apos;Medical Device&apos;</deletedAxiom>
<newAxiom>&apos;Dual Chamber Pacemaker&apos; SubClassOf &apos;Cardiac Pacemaker&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118696</classIRI>
<classLabel>FGFR3 Chondrodysplasia</classLabel>
<newAxiom>&apos;FGFR3 Chondrodysplasia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;FGFR3 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118631</classIRI>
<classLabel>Alpha Thalassemia X-Linked Mental Retardation Syndrome</classLabel>
<newAxiom>&apos;Alpha Thalassemia X-Linked Mental Retardation Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ATRX Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118633</classIRI>
<classLabel>Congenital Insensitivity to Pain with Anhidrosis</classLabel>
<newAxiom>&apos;Congenital Insensitivity to Pain with Anhidrosis&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;NTRK1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118635</classIRI>
<classLabel>Pseudoachondroplasia</classLabel>
<newAxiom>&apos;Pseudoachondroplasia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;COMP Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118636</classIRI>
<classLabel>Stiff Skin Syndrome</classLabel>
<newAxiom>&apos;Stiff Skin Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;FBN1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16187</classIRI>
<classLabel>Whole-Brain Radiotherapy</classLabel>
<deletedAxiom>&apos;Whole-Brain Radiotherapy&apos; SubClassOf &apos;Prior Extensive Radiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16117</classIRI>
<classLabel>Craniospinal Axis Irradiation in Children</classLabel>
<deletedAxiom>&apos;Craniospinal Axis Irradiation in Children&apos; SubClassOf &apos;Prior Extensive Radiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132827</classIRI>
<classLabel>Autosomal Recessive Congenital Ichthyosis 2</classLabel>
<newAxiom>&apos;Autosomal Recessive Congenital Ichthyosis 2&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ALOX12B Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5264</classIRI>
<classLabel>Bronchial Mucosa-Associated Lymphoid Tissue Lymphoma</classLabel>
<deletedAxiom>&apos;Bronchial Mucosa-Associated Lymphoid Tissue Lymphoma&apos; EquivalentTo &apos;Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue&apos; and &apos;Lung Non-Hodgkin Lymphoma&apos; and &apos;Lung Mature B-Cell Neoplasm&apos; and ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(11;18)(q21;q21)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;API2-MLT Fusion Protein Expression&apos;)) and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bronchus&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Bronchus-Associated Lymphoid Tissue&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(1;14)(p22;q32)&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MALT1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BIRC3/MALT1 Fusion Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Bronchial Mucosa-Associated Lymphoid Tissue Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156885 and &apos;Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue&apos; and &apos;Lung Non-Hodgkin Lymphoma&apos; and &apos;Lung Mature B-Cell Neoplasm&apos; and ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(11;18)(q21;q21)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;API2-MLT Fusion Protein Expression&apos;)) and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bronchus&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Bronchus-Associated Lymphoid Tissue&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(1;14)(p22;q32)&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MALT1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BIRC3/MALT1 Fusion Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5171</classIRI>
<classLabel>Metastatic Breast Carcinoid Tumor</classLabel>
<deletedAxiom>&apos;Metastatic Breast Carcinoid Tumor&apos; EquivalentTo &apos;Breast Carcinoid Tumor&apos; and &apos;Metastatic Carcinoid Tumor&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Breast Carcinoid Tumor&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156493 and &apos;Breast Carcinoid Tumor&apos; and &apos;Metastatic Carcinoid Tumor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75020</classIRI>
<classLabel>Cleidocranial Dysplasia</classLabel>
<newAxiom>&apos;Cleidocranial Dysplasia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;RUNX2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75005</classIRI>
<classLabel>Synpolydactyly-1</classLabel>
<newAxiom>&apos;Synpolydactyly-1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;HOXD13 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75008</classIRI>
<classLabel>Waardenburg Syndrome Type 1</classLabel>
<newAxiom>&apos;Waardenburg Syndrome Type 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;PAX3 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75015</classIRI>
<classLabel>Rieger Syndrome Type 1</classLabel>
<newAxiom>&apos;Rieger Syndrome Type 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;PITX2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75018</classIRI>
<classLabel>Treacher Collins Syndrome</classLabel>
<newAxiom>&apos;Treacher Collins Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;TCOF1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75011</classIRI>
<classLabel>Waardenburg Syndrome Type 2A</classLabel>
<newAxiom>&apos;Waardenburg Syndrome Type 2A&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MITF Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75100</classIRI>
<classLabel>CHARGE Syndrome</classLabel>
<newAxiom>&apos;CHARGE Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;CHD7 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75119</classIRI>
<classLabel>Loeys-Dietz Syndrome Type 1</classLabel>
<newAxiom>&apos;Loeys-Dietz Syndrome Type 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;TGFBR1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75120</classIRI>
<classLabel>Nail-Patella Syndrome</classLabel>
<newAxiom>&apos;Nail-Patella Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;LMX1B Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C146709</classIRI>
<classLabel>Blasts 5-25 Percent of Bone Marrow Nucleated Cells</classLabel>
<deletedAxiom>&apos;Blasts 5-25 Percent of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blasts 30 Percent or Less of Bone Marrow Nucleated Cells&apos;</deletedAxiom>
<newAxiom>&apos;Blasts 5-25 Percent of Bone Marrow Nucleated Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156690</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132292</classIRI>
<classLabel>Presynaptic Congenital Myasthenic Syndrome 6</classLabel>
<newAxiom>&apos;Presynaptic Congenital Myasthenic Syndrome 6&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;CHAT Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132224</classIRI>
<classLabel>Ataxia-Telangiectasia-Like Disorder 1</classLabel>
<newAxiom>&apos;Ataxia-Telangiectasia-Like Disorder 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MRE11 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C146893</classIRI>
<classLabel>Metastatic Genitourinary Carcinoma</classLabel>
<deletedAxiom>&apos;Metastatic Genitourinary Carcinoma&apos; EquivalentTo &apos;Metastatic Carcinoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Genitourinary System&apos;)</deletedAxiom>
<newAxiom>&apos;Metastatic Genitourinary Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156484 and &apos;Metastatic Carcinoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Genitourinary System&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75460</classIRI>
<classLabel>Holoprosencephaly Type 5</classLabel>
<newAxiom>&apos;Holoprosencephaly Type 5&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ZIC1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75475</classIRI>
<classLabel>Holoprosencephaly Type 4</classLabel>
<newAxiom>&apos;Holoprosencephaly Type 4&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;TGIF1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75488</classIRI>
<classLabel>Rett Syndrome</classLabel>
<newAxiom>&apos;Rett Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MECP2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75481</classIRI>
<classLabel>Orofaciodigital Syndrome Type 1</classLabel>
<newAxiom>&apos;Orofaciodigital Syndrome Type 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;OFD1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75482</classIRI>
<classLabel>Duchenne Muscular Dystrophy</classLabel>
<newAxiom>&apos;Duchenne Muscular Dystrophy&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;DMD Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75485</classIRI>
<classLabel>X-Linked Cornelia De Lange Syndrome</classLabel>
<newAxiom>&apos;X-Linked Cornelia De Lange Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SMC1A Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75487</classIRI>
<classLabel>Pelizaeus-Merzbacher Disease</classLabel>
<newAxiom>&apos;Pelizaeus-Merzbacher Disease&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;PLP1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75486</classIRI>
<classLabel>Menkes Disease</classLabel>
<newAxiom>&apos;Menkes Disease&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ATP7A Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75559</classIRI>
<classLabel>Farmer</classLabel>
<deletedAxiom>&apos;Farmer&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Farmer&apos; SubClassOf &apos;Farming, Fishing, and Forestry Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36076</classIRI>
<classLabel>Malignant Reproductive System Neoplasm</classLabel>
<deletedAxiom>&apos;Malignant Reproductive System Neoplasm&apos; EquivalentTo &apos;Reproductive System Neoplasm&apos; and &apos;Malignant Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Malignant Reproductive System Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156484 and &apos;Reproductive System Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61268</classIRI>
<classLabel>Gaucher Disease</classLabel>
<newAxiom>&apos;Gaucher Disease&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GBA Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61251</classIRI>
<classLabel>Metachromatic Leukodystrophy</classLabel>
<newAxiom>&apos;Metachromatic Leukodystrophy&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ARSA Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61252</classIRI>
<classLabel>Adrenoleukodystrophy</classLabel>
<newAxiom>&apos;Adrenoleukodystrophy&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ABCD1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61255</classIRI>
<classLabel>Lesch-Nyhan Syndrome</classLabel>
<newAxiom>&apos;Lesch-Nyhan Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;HPRT1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61254</classIRI>
<classLabel>Krabbe Disease</classLabel>
<newAxiom>&apos;Krabbe Disease&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GALC Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61258</classIRI>
<classLabel>Neuronal Ceroid Lipofuscinosis Type 3</classLabel>
<newAxiom>&apos;Neuronal Ceroid Lipofuscinosis Type 3&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156970</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112831</classIRI>
<classLabel>Ichthyosis Acquisita</classLabel>
<deletedAxiom>&apos;Ichthyosis Acquisita&apos; SubClassOf &apos;Ichthyosis Vulgaris&apos;</deletedAxiom>
<newAxiom>&apos;Ichthyosis Acquisita&apos; SubClassOf &apos;Ichthyosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113769</classIRI>
<classLabel>CACNA1D Gene</classLabel>
<newAxiom>&apos;CACNA1D Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Aldosterone-Producing Adrenal Cortex Adenoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113762</classIRI>
<classLabel>ATP1A1 Gene</classLabel>
<newAxiom>&apos;ATP1A1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Aldosterone-Producing Adrenal Cortex Adenoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113765</classIRI>
<classLabel>ATP2B3 Gene</classLabel>
<newAxiom>&apos;ATP2B3 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Aldosterone-Producing Adrenal Cortex Adenoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95190</classIRI>
<classLabel>Rhodium</classLabel>
<deletedAxiom>&apos;Rhodium&apos; SubClassOf &apos;Metal&apos;</deletedAxiom>
<newAxiom>&apos;Rhodium&apos; SubClassOf &apos;Platinum-Group Metal&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95182</classIRI>
<classLabel>Osmium</classLabel>
<deletedAxiom>&apos;Osmium&apos; SubClassOf &apos;Metal&apos;</deletedAxiom>
<newAxiom>&apos;Osmium&apos; SubClassOf &apos;Platinum-Group Metal&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95184</classIRI>
<classLabel>Palladium</classLabel>
<deletedAxiom>&apos;Palladium&apos; SubClassOf &apos;Metal&apos;</deletedAxiom>
<newAxiom>&apos;Palladium&apos; SubClassOf &apos;Platinum-Group Metal&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95183</classIRI>
<classLabel>Iridium</classLabel>
<deletedAxiom>&apos;Iridium&apos; SubClassOf &apos;Metal&apos;</deletedAxiom>
<newAxiom>&apos;Iridium&apos; SubClassOf &apos;Platinum-Group Metal&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C147065</classIRI>
<classLabel>Metastatic Well Differentiated Neuroendocrine Neoplasm</classLabel>
<deletedAxiom>&apos;Metastatic Well Differentiated Neuroendocrine Neoplasm&apos; EquivalentTo &apos;Metastatic Malignant Neoplasm&apos; and &apos;Neuroendocrine Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Well Differentiated Neuroendocrine Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Metastatic Well Differentiated Neuroendocrine Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156485 and (&apos;Disease_Has_Finding&apos; some &apos;Well Differentiated Neuroendocrine Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113334</classIRI>
<classLabel>Histone-Lysine N-Methyltransferase EZH2 Inhibitor GSK2816126</classLabel>
<deletedAxiom>&apos;Histone-Lysine N-Methyltransferase EZH2 Inhibitor GSK2816126&apos; SubClassOf &apos;Enzyme Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Histone-Lysine N-Methyltransferase EZH2 Inhibitor GSK2816126&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156804</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95838</classIRI>
<classLabel>KCNJ5 Gene</classLabel>
<newAxiom>&apos;KCNJ5 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Adrenal Cortex Clear Cell Adenoma&apos;</newAxiom>
<newAxiom>&apos;KCNJ5 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Adrenal Cortex Compact Cell Adenoma&apos;</newAxiom>
<newAxiom>&apos;KCNJ5 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Aldosterone-Producing Adrenal Cortex Adenoma&apos;</newAxiom>
<newAxiom>&apos;KCNJ5 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Adrenal Cortex Mixed Cell Adenoma&apos;</newAxiom>
<newAxiom>&apos;KCNJ5 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Adrenal Cortex Glomerulosa Cell Adenoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6431</classIRI>
<classLabel>Metastatic Carcinoid Tumor</classLabel>
<deletedAxiom>&apos;Metastatic Carcinoid Tumor&apos; EquivalentTo &apos;Carcinoid Tumor&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Metastatic Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Trabecular Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Organoid Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Rosette Formation&apos;)</deletedAxiom>
<newAxiom>&apos;Metastatic Carcinoid Tumor&apos; EquivalentTo &apos;Metastatic Well Differentiated Neuroendocrine Neoplasm&apos; and &apos;Carcinoid Tumor&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Trabecular Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Organoid Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Rosette Formation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C152064</classIRI>
<classLabel>Revesz Syndrome</classLabel>
<newAxiom>&apos;Revesz Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;TINF2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81991</classIRI>
<classLabel>Thyroid Antimicrosomal Antibody Measurement</classLabel>
<deletedAxiom>&apos;Thyroid Antimicrosomal Antibody Measurement&apos; SubClassOf &apos;Immunology Test&apos;</deletedAxiom>
<newAxiom>&apos;Thyroid Antimicrosomal Antibody Measurement&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131422</classIRI>
<classLabel>Cholesterol Side-Chain Cleavage Deficiency</classLabel>
<newAxiom>&apos;Cholesterol Side-Chain Cleavage Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;CYP11A1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17599</classIRI>
<classLabel>Immunologist</classLabel>
<deletedAxiom>&apos;Immunologist&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Immunologist&apos; SubClassOf &apos;Medical Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4166</classIRI>
<classLabel>Adrenal Cortex Glomerulosa Cell Adenoma</classLabel>
<deletedAxiom>&apos;Adrenal Cortex Glomerulosa Cell Adenoma&apos; EquivalentTo &apos;Adrenal Cortex Adenoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Glomerulosa Cell&apos;)</deletedAxiom>
<newAxiom>&apos;Adrenal Cortex Glomerulosa Cell Adenoma&apos; EquivalentTo &apos;Adrenal Cortex Adenoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Glomerulosa Cell&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;KCNJ5 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156934)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4165</classIRI>
<classLabel>Adrenal Cortex Clear Cell Adenoma</classLabel>
<deletedAxiom>&apos;Adrenal Cortex Clear Cell Adenoma&apos; EquivalentTo &apos;Clear Cell Adenoma&apos; and &apos;Adrenal Cortex Adenoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Adrenal Cortical Clear Cell&apos;)</deletedAxiom>
<newAxiom>&apos;Adrenal Cortex Clear Cell Adenoma&apos; EquivalentTo &apos;Clear Cell Adenoma&apos; and &apos;Adrenal Cortex Adenoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Adrenal Cortical Clear Cell&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;KCNJ5 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156934)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4167</classIRI>
<classLabel>Adrenal Cortex Mixed Cell Adenoma</classLabel>
<deletedAxiom>&apos;Adrenal Cortex Mixed Cell Adenoma&apos; EquivalentTo &apos;Mixed Neoplasm&apos; and &apos;Adrenal Cortex Adenoma&apos;</deletedAxiom>
<newAxiom>&apos;Adrenal Cortex Mixed Cell Adenoma&apos; EquivalentTo &apos;Mixed Neoplasm&apos; and &apos;Adrenal Cortex Adenoma&apos; and (&apos;Disease_Mapped_To_Gene&apos; some &apos;KCNJ5 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156934)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4163</classIRI>
<classLabel>Adrenal Cortex Compact Cell Adenoma</classLabel>
<deletedAxiom>&apos;Adrenal Cortex Compact Cell Adenoma&apos; EquivalentTo &apos;Adrenal Cortex Adenoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Adrenal Cortical Compact Cell&apos;)</deletedAxiom>
<newAxiom>&apos;Adrenal Cortex Compact Cell Adenoma&apos; EquivalentTo &apos;Adrenal Cortex Adenoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Adrenal Cortical Compact Cell&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;KCNJ5 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156934)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4154</classIRI>
<classLabel>Parathyroid Gland Chief Cell Adenoma</classLabel>
<deletedAxiom>&apos;Parathyroid Gland Chief Cell Adenoma&apos; EquivalentTo &apos;Parathyroid Gland Adenoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Chief Cell&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Tumor Vascular Invasion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Capsular Invasion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Perineural Invasion&apos;)</deletedAxiom>
<newAxiom>&apos;Parathyroid Gland Chief Cell Adenoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156757 and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Chief Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131533</classIRI>
<classLabel>Bohring-Opitz Syndrome</classLabel>
<newAxiom>&apos;Bohring-Opitz Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ASXL1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4008</classIRI>
<classLabel>Recurrent Gallbladder Carcinoma</classLabel>
<deletedAxiom>&apos;Recurrent Gallbladder Carcinoma&apos; EquivalentTo &apos;Gallbladder Carcinoma&apos; and &apos;Recurrent Digestive System Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Gallbladder Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156782 and &apos;Gallbladder Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17815</classIRI>
<classLabel>Breast Cancer Type 1 Susceptibility Protein</classLabel>
<deletedAxiom>&apos;Breast Cancer Type 1 Susceptibility Protein&apos; EquivalentTo &apos;Regulatory Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ATM Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cancer Susceptibility Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;BARD1 Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Estrogen Receptor Regulation by CARM1 Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;G2/M Checkpoint Pathway&apos;) and (&apos;Gene_Product_Is_Biomarker_Type&apos; some &apos;Tumor Marker&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Prostate Carcinoma&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Colon Carcinoma&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Malignant Ovarian Neoplasm&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Hereditary Breast and Ovarian Cancer Syndrome&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;C2H2 Zinc Finger&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;BRCT Domain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Nuclear Localization Signal&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;SWI/SNF Family Complex&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Transcription Repressor/Corepressor&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Recombination Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Binding&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Cycle Checkpoint&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Regulation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Recombination Repair&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Double Strand Break Repair&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Chromatin Remodeling&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;BRCA1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Breast Cancer Type 1 Susceptibility Protein&apos; EquivalentTo &apos;Regulatory Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ATM Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cancer Susceptibility Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;BARD1 Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Estrogen Receptor Regulation by CARM1 Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;G2/M Checkpoint Pathway&apos;) and (&apos;Gene_Product_Is_Biomarker_Type&apos; some &apos;Tumor Marker&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Prostate Carcinoma&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Colon Carcinoma&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Malignant Ovarian Neoplasm&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Hereditary Breast and Ovarian Cancer Syndrome&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;C2H2 Zinc Finger&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;BRCT Domain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Nuclear Localization Signal&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Transcription Repressor/Corepressor&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Recombination Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Binding&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Cycle Checkpoint&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Regulation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Recombination Repair&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Double Strand Break Repair&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Chromatin Remodeling&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;BRCA1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131133</classIRI>
<classLabel>Sclerosteosis</classLabel>
<newAxiom>&apos;Sclerosteosis&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SOST Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4496</classIRI>
<classLabel>Common Blue Nevus</classLabel>
<deletedAxiom>&apos;Common Blue Nevus&apos; EquivalentTo &apos;Blue Nevus&apos; and (&apos;Disease_Excludes_Finding&apos; some &apos;Increased Cellularity Present&apos;)</deletedAxiom>
<newAxiom>&apos;Common Blue Nevus&apos; EquivalentTo &apos;Blue Nevus&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Spindle Melanocyte&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Increased Cellularity Present&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4447</classIRI>
<classLabel>Benign Retroperitoneal Neoplasm</classLabel>
<deletedAxiom>&apos;Benign Retroperitoneal Neoplasm&apos; EquivalentTo &apos;Retroperitoneal Neoplasm&apos; and &apos;Benign Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Retroperitoneum&apos;)</deletedAxiom>
<newAxiom>&apos;Benign Retroperitoneal Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156713 and &apos;Retroperitoneal Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Retroperitoneum&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C111814</classIRI>
<classLabel>Griscelli Syndrome Type 2</classLabel>
<newAxiom>&apos;Griscelli Syndrome Type 2&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;RAB27A Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4893</classIRI>
<classLabel>Benign Urinary System Neoplasm</classLabel>
<deletedAxiom>&apos;Benign Urinary System Neoplasm&apos; EquivalentTo &apos;Urinary System Neoplasm&apos; and &apos;Benign Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Urinary System&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Squamous Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Adenocarcinoma Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Transitional Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Neoplastic Lymphocyte&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Connective and Soft Tissue Cell&apos;)</deletedAxiom>
<newAxiom>&apos;Benign Urinary System Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156483 and &apos;Urinary System Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Urinary System&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Squamous Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Adenocarcinoma Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Transitional Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Neoplastic Lymphocyte&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Connective and Soft Tissue Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4875</classIRI>
<classLabel>Reproductive System Disorder</classLabel>
<deletedAxiom>&apos;Reproductive System Disorder&apos; SubClassOf &apos;Disorder by Site&apos;</deletedAxiom>
<newAxiom>&apos;Reproductive System Disorder&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156660</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4739</classIRI>
<classLabel>Acrosyringeal Nevus</classLabel>
<deletedAxiom>&apos;Acrosyringeal Nevus&apos; EquivalentTo &apos;Melanocytic Skin Neoplasm&apos; and &apos;Melanocytic Nevus&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Sweat Gland&apos;)</deletedAxiom>
<newAxiom>&apos;Acrosyringeal Nevus&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62517</classIRI>
<classLabel>Hsp90 Inhibitor BIIB021</classLabel>
<deletedAxiom>&apos;Hsp90 Inhibitor BIIB021&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Hsp90 Inhibitor BIIB021&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126866</classIRI>
<classLabel>Niemann-Pick Disease, Type B</classLabel>
<newAxiom>&apos;Niemann-Pick Disease, Type B&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SMPD1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126876</classIRI>
<classLabel>Langer Mesomelic Dysplasia</classLabel>
<newAxiom>&apos;Langer Mesomelic Dysplasia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SHOX Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C151995</classIRI>
<classLabel>Resectable Pancreatic Ductal Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Resectable Pancreatic Ductal Adenocarcinoma&apos; EquivalentTo &apos;Resectable Pancreatic Carcinoma&apos; and &apos;Pancreatic Ductal Adenocarcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Resectable Pancreatic Ductal Adenocarcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156906 and &apos;Pancreatic Ductal Adenocarcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C151981</classIRI>
<classLabel>Pelvic Rhabdomyosarcoma</classLabel>
<deletedAxiom>&apos;Pelvic Rhabdomyosarcoma&apos; EquivalentTo &apos;Rhabdomyosarcoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Pelvis&apos;)</deletedAxiom>
<newAxiom>&apos;Pelvic Rhabdomyosarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156715 and &apos;Rhabdomyosarcoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Pelvis&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C151984</classIRI>
<classLabel>Pelvic Undifferentiated High Grade Pleomorphic Sarcoma</classLabel>
<deletedAxiom>&apos;Pelvic Undifferentiated High Grade Pleomorphic Sarcoma&apos; EquivalentTo &apos;Undifferentiated High Grade Pleomorphic Sarcoma of Bone&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Pelvis&apos;)</deletedAxiom>
<newAxiom>&apos;Pelvic Undifferentiated High Grade Pleomorphic Sarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156715 and &apos;Undifferentiated High Grade Pleomorphic Sarcoma of Bone&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Pelvis&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C151948</classIRI>
<classLabel>CD16/IL15/CD33 Trispecific Killer Cell Engager</classLabel>
<deletedAxiom>&apos;CD16/IL15/CD33 Trispecific Killer Cell Engager&apos; SubClassOf &apos;Gene Therapy Agent&apos;</deletedAxiom>
<deletedAxiom>&apos;CD16/IL15/CD33 Trispecific Killer Cell Engager&apos; SubClassOf &apos;Gene Transfer or Gene Delivery Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126561</classIRI>
<classLabel>Niemann-Pick Disease, Type A</classLabel>
<newAxiom>&apos;Niemann-Pick Disease, Type A&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SMPD1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126560</classIRI>
<classLabel>Leri-Weill Dyschondrosteosis</classLabel>
<newAxiom>&apos;Leri-Weill Dyschondrosteosis&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SHOX Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126558</classIRI>
<classLabel>Combined Lipase Deficiency</classLabel>
<newAxiom>&apos;Combined Lipase Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;LMF1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82387</classIRI>
<classLabel>Hsp90 Inhibitor HSP990</classLabel>
<deletedAxiom>&apos;Hsp90 Inhibitor HSP990&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Hsp90 Inhibitor HSP990&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82419</classIRI>
<classLabel>Doxorubicin-Eluting Beads</classLabel>
<deletedAxiom>&apos;Doxorubicin-Eluting Beads&apos; SubClassOf &apos;Anthracycline Antineoplastic Antibiotic&apos;</deletedAxiom>
<newAxiom>&apos;Doxorubicin-Eluting Beads&apos; SubClassOf &apos;Doxorubicin Preparation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126352</classIRI>
<classLabel>X-Linked Dyskeratosis Congenita</classLabel>
<newAxiom>&apos;X-Linked Dyskeratosis Congenita&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;DKC1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82691</classIRI>
<classLabel>Hsp90 Inhibitor AB-010</classLabel>
<deletedAxiom>&apos;Hsp90 Inhibitor AB-010&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Hsp90 Inhibitor AB-010&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5099</classIRI>
<classLabel>Resectable Pancreatic Carcinoma</classLabel>
<deletedAxiom>&apos;Resectable Pancreatic Carcinoma&apos; EquivalentTo &apos;Resectable Carcinoma&apos; and &apos;Pancreatic Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Resectable Pancreatic Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156909 and &apos;Pancreatic Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131650</classIRI>
<classLabel>Sebastian Syndrome</classLabel>
<newAxiom>&apos;Sebastian Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MYH9 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131646</classIRI>
<classLabel>May-Hegglin Anomaly</classLabel>
<newAxiom>&apos;May-Hegglin Anomaly&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MYH9 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131642</classIRI>
<classLabel>Fechtner Syndrome</classLabel>
<newAxiom>&apos;Fechtner Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MYH9 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131639</classIRI>
<classLabel>Epstein Syndrome</classLabel>
<newAxiom>&apos;Epstein Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MYH9 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7993</classIRI>
<classLabel>Parathyroid Gland Clear Cell Adenoma</classLabel>
<deletedAxiom>&apos;Parathyroid Gland Clear Cell Adenoma&apos; EquivalentTo &apos;Parathyroid Gland Adenoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Clear Cell&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Tumor Vascular Invasion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Capsular Invasion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Perineural Invasion&apos;)</deletedAxiom>
<newAxiom>&apos;Parathyroid Gland Clear Cell Adenoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156757 and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Clear Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7994</classIRI>
<classLabel>Parathyroid Gland Mixed Cell Type Adenoma</classLabel>
<deletedAxiom>&apos;Parathyroid Gland Mixed Cell Type Adenoma&apos; EquivalentTo &apos;Parathyroid Gland Adenoma&apos; and &apos;Mixed Cell Adenoma&apos; and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Chief Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Oncocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Clear Cell&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Tumor Vascular Invasion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Capsular Invasion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Perineural Invasion&apos;)</deletedAxiom>
<newAxiom>&apos;Parathyroid Gland Mixed Cell Type Adenoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156757 and &apos;Mixed Cell Adenoma&apos; and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Chief Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Oncocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Clear Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129022</classIRI>
<classLabel>Deafness, Autosomal Recessive 1A</classLabel>
<newAxiom>&apos;Deafness, Autosomal Recessive 1A&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GJB2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7877</classIRI>
<classLabel>Localized Resectable Adult Liver Carcinoma</classLabel>
<deletedAxiom>&apos;Localized Resectable Adult Liver Carcinoma&apos; EquivalentTo &apos;Resectable Carcinoma&apos; and &apos;Localized Carcinoma&apos; and &apos;Resectable Malignant Liver Neoplasm&apos; and &apos;Adult Liver Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Localized Resectable Adult Liver Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156909 and &apos;Localized Carcinoma&apos; and &apos;Resectable Malignant Liver Neoplasm&apos; and &apos;Adult Liver Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129074</classIRI>
<classLabel>Immunodeficiency with Hyper-IgM Type 2</classLabel>
<newAxiom>&apos;Immunodeficiency with Hyper-IgM Type 2&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;AICDA Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120113</classIRI>
<classLabel>Short Stature Homeobox Deficiency</classLabel>
<newAxiom>&apos;Short Stature Homeobox Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SHOX Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77872</classIRI>
<classLabel>Ganetespib</classLabel>
<deletedAxiom>&apos;Ganetespib&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Ganetespib&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C134509</classIRI>
<classLabel>Deleterious PPP2R2A Gene Mutation</classLabel>
<newAxiom>&apos;Deleterious PPP2R2A Gene Mutation&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156750</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38409</classIRI>
<classLabel>PRKACA Gene</classLabel>
<newAxiom>&apos;PRKACA Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Cortisol-Producing Adrenal Cortex Adenoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C134448</classIRI>
<classLabel>HSP90alpha/beta Inhibitor TAS-116</classLabel>
<deletedAxiom>&apos;HSP90alpha/beta Inhibitor TAS-116&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;HSP90alpha/beta Inhibitor TAS-116&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C135088</classIRI>
<classLabel>Spondyloperipheral Dysplasia</classLabel>
<newAxiom>&apos;Spondyloperipheral Dysplasia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;COL2A1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101227</classIRI>
<classLabel>Hsp90 Inhibitor PU-H71</classLabel>
<deletedAxiom>&apos;Hsp90 Inhibitor PU-H71&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Hsp90 Inhibitor PU-H71&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101215</classIRI>
<classLabel>Mullerian Inhibiting Factor Deficiency</classLabel>
<newAxiom>&apos;Mullerian Inhibiting Factor Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;AMH Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8612</classIRI>
<classLabel>Benign Peritoneal Neoplasm</classLabel>
<deletedAxiom>&apos;Benign Peritoneal Neoplasm&apos; EquivalentTo &apos;Peritoneal Neoplasm&apos; and &apos;Benign Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Peritoneum&apos;)</deletedAxiom>
<newAxiom>&apos;Benign Peritoneal Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156713 and &apos;Peritoneal Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Peritoneum&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8615</classIRI>
<classLabel>Metastatic Malignant Neoplasm in the Abdominal Cavity</classLabel>
<deletedAxiom>&apos;Metastatic Malignant Neoplasm in the Abdominal Cavity&apos; EquivalentTo &apos;Metastatic Malignant Neoplasm&apos; and (&apos;Disease_Has_Metastatic_Anatomic_Site&apos; some &apos;Abdomen&apos;)</deletedAxiom>
<newAxiom>&apos;Metastatic Malignant Neoplasm in the Abdominal Cavity&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156714 and &apos;Metastatic Malignant Neoplasm&apos; and (&apos;Disease_Has_Metastatic_Anatomic_Site&apos; some &apos;Abdomen&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129930</classIRI>
<classLabel>MASA Syndrome</classLabel>
<newAxiom>&apos;MASA Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;L1CAM Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129931</classIRI>
<classLabel>Mental Retardation, X-linked 102</classLabel>
<newAxiom>&apos;Mental Retardation, X-linked 102&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;DDX3X Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129978</classIRI>
<classLabel>Mucolipidosis Type III Gamma</classLabel>
<deletedAxiom>&apos;Mucolipidosis Type III Gamma&apos; SubClassOf &apos;Rare Non-Neoplastic Disorder&apos;</deletedAxiom>
<newAxiom>&apos;Mucolipidosis Type III Gamma&apos; SubClassOf &apos;Mucolipidosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129976</classIRI>
<classLabel>Kleefstra Syndrome</classLabel>
<newAxiom>&apos;Kleefstra Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;EHMT1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129977</classIRI>
<classLabel>Mitochondrial DNA Depletion Syndrome 12</classLabel>
<newAxiom>&apos;Mitochondrial DNA Depletion Syndrome 12&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SLC25A4 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19447</classIRI>
<classLabel>Environmental and Occupational Exposure</classLabel>
<deletedAxiom>&apos;Environmental and Occupational Exposure&apos; SubClassOf &apos;Exposure&apos;</deletedAxiom>
<newAxiom>&apos;Environmental and Occupational Exposure&apos; SubClassOf &apos;Finding by Cause&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129727</classIRI>
<classLabel>Autoimmune Polyglandular Syndrome Type 1</classLabel>
<newAxiom>&apos;Autoimmune Polyglandular Syndrome Type 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;AIRE Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C140252</classIRI>
<classLabel>HRAS NM_005343.3:c.35_36delGCinsTA</classLabel>
<newAxiom>&apos;HRAS NM_005343.3:c.35_36delGCinsTA&apos; SubClassOf &apos;Gene_Mutant_Encodes_Gene_Product_Sequence_Variation&apos; some &apos;HRAS NP_005334.1:p.G12V&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C140253</classIRI>
<classLabel>HRAS NP_005334.1:p.G12V</classLabel>
<deletedAxiom>&apos;HRAS NP_005334.1:p.G12V&apos; SubClassOf &apos;HRAS Protein Variant&apos;</deletedAxiom>
<newAxiom>&apos;HRAS NP_005334.1:p.G12V&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156884</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C140250</classIRI>
<classLabel>HRAS NM_005343.3:c.35GT</classLabel>
<newAxiom>&apos;HRAS NM_005343.3:c.35GT&apos; SubClassOf &apos;Gene_Mutant_Encodes_Gene_Product_Sequence_Variation&apos; some &apos;HRAS NP_005334.1:p.G12V&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115207</classIRI>
<classLabel>Congenital Amegakaryocytic Thrombocytopenia</classLabel>
<newAxiom>&apos;Congenital Amegakaryocytic Thrombocytopenia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MPL Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129874</classIRI>
<classLabel>Deafness, Autosomal Recessive 39</classLabel>
<newAxiom>&apos;Deafness, Autosomal Recessive 39&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;HGF Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115245</classIRI>
<classLabel>Metastatic Digestive System Neuroendocrine Tumor G1</classLabel>
<deletedAxiom>&apos;Metastatic Digestive System Neuroendocrine Tumor G1&apos; EquivalentTo &apos;Metastatic Carcinoid Tumor&apos; and &apos;Digestive System Neuroendocrine Tumor G1&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Digestive System Neuroendocrine Tumor G1&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156492 and &apos;Metastatic Carcinoid Tumor&apos; and &apos;Digestive System Neuroendocrine Tumor G1&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C154621</classIRI>
<classLabel>Advanced Well Differentiated Neuroendocrine Neoplasm</classLabel>
<deletedAxiom>&apos;Advanced Well Differentiated Neuroendocrine Neoplasm&apos; EquivalentTo &apos;Metastatic Well Differentiated Neuroendocrine Neoplasm&apos; and &apos;Advanced Malignant Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Well Differentiated Neuroendocrine Neoplasm&apos; EquivalentTo &apos;Metastatic Well Differentiated Neuroendocrine Neoplasm&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156486</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19837</classIRI>
<classLabel>hSWI/SNF</classLabel>
<newAxiom>&apos;hSWI/SNF&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Chromatin Remodeling&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19871</classIRI>
<classLabel>E-RC1</classLabel>
<deletedAxiom>&apos;E-RC1&apos; SubClassOf &apos;Protein or Riboprotein Complex&apos;</deletedAxiom>
<deletedAxiom>&apos;E-RC1&apos; SubClassOf &apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;hSWI/SNF&apos;</deletedAxiom>
<newAxiom>&apos;E-RC1&apos; SubClassOf &apos;hSWI/SNF&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129303</classIRI>
<classLabel>Congenital Bilateral Aplasia of the Vas Deferens</classLabel>
<newAxiom>&apos;Congenital Bilateral Aplasia of the Vas Deferens&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;CFTR Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129308</classIRI>
<classLabel>Schinzel-Giedion Midface-Retraction Syndrome</classLabel>
<newAxiom>&apos;Schinzel-Giedion Midface-Retraction Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SETBP1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129425</classIRI>
<classLabel>Onalespib Lactate</classLabel>
<deletedAxiom>&apos;Onalespib Lactate&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Onalespib Lactate&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8639</classIRI>
<classLabel>Resectable Small Intestinal Carcinoma</classLabel>
<deletedAxiom>&apos;Resectable Small Intestinal Carcinoma&apos; EquivalentTo &apos;Resectable Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Resectable Small Intestinal Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156909 and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8640</classIRI>
<classLabel>Resectable Extrahepatic Bile Duct Carcinoma</classLabel>
<deletedAxiom>&apos;Resectable Extrahepatic Bile Duct Carcinoma&apos; EquivalentTo &apos;Resectable Carcinoma&apos; and &apos;Extrahepatic Bile Duct Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Resectable Extrahepatic Bile Duct Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156909 and &apos;Extrahepatic Bile Duct Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78846</classIRI>
<classLabel>Hsp90 Inhibitor BIIB028</classLabel>
<deletedAxiom>&apos;Hsp90 Inhibitor BIIB028&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Hsp90 Inhibitor BIIB028&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78843</classIRI>
<classLabel>Oral Hsp90 Inhibitor IPI-493</classLabel>
<deletedAxiom>&apos;Oral Hsp90 Inhibitor IPI-493&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Oral Hsp90 Inhibitor IPI-493&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133725</classIRI>
<classLabel>Familial Hypertrophic Cardiomyopathy Type 4</classLabel>
<newAxiom>&apos;Familial Hypertrophic Cardiomyopathy Type 4&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MYBPC3 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133712</classIRI>
<classLabel>Metastatic Paraganglioma</classLabel>
<deletedAxiom>&apos;Metastatic Paraganglioma&apos; EquivalentTo &apos;Metastatic Malignant Neoplasm&apos; and &apos;Malignant Paraganglioma&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Paraganglioma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156485 and &apos;Malignant Paraganglioma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133743</classIRI>
<classLabel>Cortical Dysplasia-Focal Epilepsy Syndrome</classLabel>
<newAxiom>&apos;Cortical Dysplasia-Focal Epilepsy Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;CNTNAP2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133417</classIRI>
<classLabel>Pathologic Stage IC Esophageal Adenocarcinoma AJCC v8</classLabel>
<deletedAxiom>&apos;Pathologic Stage IC Esophageal Adenocarcinoma AJCC v8&apos; SubClassOf &apos;Pathologic Stage I Esophageal Adenocarcinoma AJCC v8&apos;</deletedAxiom>
<newAxiom>&apos;Pathologic Stage IC Esophageal Adenocarcinoma AJCC v8&apos; EquivalentTo &apos;Pathologic Stage I Esophageal Adenocarcinoma AJCC v8&apos; and (&apos;Disease_Is_Stage&apos; some &apos;Stage IC&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39902</classIRI>
<classLabel>Prostate Basal Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Prostate Basal Cell Carcinoma&apos; EquivalentTo &apos;Invasive Prostate Carcinoma&apos; and &apos;Malignant Basal Cell Neoplasm&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Non-Cutaneous Basaloid Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Urinary Retention&apos;)</deletedAxiom>
<newAxiom>&apos;Prostate Basal Cell Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156767 and &apos;Invasive Prostate Carcinoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Non-Cutaneous Basaloid Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Urinary Retention&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98573</classIRI>
<classLabel>Factor V Leiden</classLabel>
<newAxiom>&apos;Factor V Leiden&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;F5 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98699</classIRI>
<classLabel>5 Alpha Steroid Reductase 2 Deficiency</classLabel>
<newAxiom>&apos;5 Alpha Steroid Reductase 2 Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SRD5A2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98670</classIRI>
<classLabel>Werdnig-Hoffmann Disease</classLabel>
<newAxiom>&apos;Werdnig-Hoffmann Disease&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SMN1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98815</classIRI>
<classLabel>Antithrombin III Deficiency</classLabel>
<newAxiom>&apos;Antithrombin III Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SERPINC1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98946</classIRI>
<classLabel>High Molecular Weight Kininogen Deficiency</classLabel>
<newAxiom>&apos;High Molecular Weight Kininogen Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;KNG1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98933</classIRI>
<classLabel>Glucose-6-Phosphate Dehydrogenase Deficiency</classLabel>
<newAxiom>&apos;Glucose-6-Phosphate Dehydrogenase Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;G6PD Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84397</classIRI>
<classLabel>Alpha-1 Antitrypsin Deficiency</classLabel>
<newAxiom>&apos;Alpha-1 Antitrypsin Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SERPINA1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148369</classIRI>
<classLabel>Muscular Dystrophy Congenital, LMNA-Related</classLabel>
<newAxiom>&apos;Muscular Dystrophy Congenital, LMNA-Related&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;LMNA Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84545</classIRI>
<classLabel>Alexander Disease</classLabel>
<newAxiom>&apos;Alexander Disease&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GFAP Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84538</classIRI>
<classLabel>Medium-Chain Acyl-CoA Dehydrogenase Deficiency</classLabel>
<newAxiom>&apos;Medium-Chain Acyl-CoA Dehydrogenase Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ACADM Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84526</classIRI>
<classLabel>Acatalasemia</classLabel>
<newAxiom>&apos;Acatalasemia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;CAT Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84524</classIRI>
<classLabel>5&apos; 10&apos; Methylenetetrahydrofolate Reductase Deficiency</classLabel>
<newAxiom>&apos;5&apos; 10&apos; Methylenetetrahydrofolate Reductase Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MTHFR Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84628</classIRI>
<classLabel>Cerebrotendinous Xanthomatosis</classLabel>
<newAxiom>&apos;Cerebrotendinous Xanthomatosis&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;CYP27A1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84610</classIRI>
<classLabel>Camurati-Engelmann Syndrome</classLabel>
<newAxiom>&apos;Camurati-Engelmann Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;TGFB1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84609</classIRI>
<classLabel>Campomelic Dysplasia</classLabel>
<newAxiom>&apos;Campomelic Dysplasia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SOX9 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84606</classIRI>
<classLabel>CADASIL Syndrome</classLabel>
<newAxiom>&apos;CADASIL Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;NOTCH3 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84666</classIRI>
<classLabel>De Sanctis-Cacchione Syndrome</classLabel>
<newAxiom>&apos;De Sanctis-Cacchione Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ERCC6 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84665</classIRI>
<classLabel>Darier Disease</classLabel>
<newAxiom>&apos;Darier Disease&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ATP2A2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84650</classIRI>
<classLabel>Connexin 26 Gene Anomaly</classLabel>
<newAxiom>&apos;Connexin 26 Gene Anomaly&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GJB2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84657</classIRI>
<classLabel>Cryopyrin-Associated Periodic Syndrome</classLabel>
<newAxiom>&apos;Cryopyrin-Associated Periodic Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;NLRP3 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84656</classIRI>
<classLabel>Crigler-Najjar Syndrome</classLabel>
<newAxiom>&apos;Crigler-Najjar Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;UGT1A1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84653</classIRI>
<classLabel>Craniofacial Dysostosis</classLabel>
<newAxiom>&apos;Craniofacial Dysostosis&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;FGFR2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84691</classIRI>
<classLabel>Epidermolysis Bullosa Dystrophica</classLabel>
<newAxiom>&apos;Epidermolysis Bullosa Dystrophica&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;COL7A1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84676</classIRI>
<classLabel>Donohue Syndrome</classLabel>
<newAxiom>&apos;Donohue Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;INSR Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84745</classIRI>
<classLabel>Hajdu-Cheney Syndrome</classLabel>
<newAxiom>&apos;Hajdu-Cheney Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;NOTCH2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84739</classIRI>
<classLabel>GM1 Gangliosidosis</classLabel>
<newAxiom>&apos;GM1 Gangliosidosis&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GLB1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84729</classIRI>
<classLabel>Gilbert Syndrome</classLabel>
<newAxiom>&apos;Gilbert Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;UGT1A1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84728</classIRI>
<classLabel>Giant Axonal Neuropathy</classLabel>
<newAxiom>&apos;Giant Axonal Neuropathy&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GAN Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84710</classIRI>
<classLabel>Farber Lipogranulomatosis</classLabel>
<newAxiom>&apos;Farber Lipogranulomatosis&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ASAH1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84711</classIRI>
<classLabel>Fatal Familial Insomnia</classLabel>
<newAxiom>&apos;Fatal Familial Insomnia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;PRNP Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84717</classIRI>
<classLabel>Fragile X Syndrome</classLabel>
<newAxiom>&apos;Fragile X Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;FMR1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84715</classIRI>
<classLabel>Focal Dermal Hypoplasia</classLabel>
<newAxiom>&apos;Focal Dermal Hypoplasia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;PORCN Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84787</classIRI>
<classLabel>Incontinentia Pigmenti</classLabel>
<newAxiom>&apos;Incontinentia Pigmenti&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;IKBKG Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84778</classIRI>
<classLabel>Ichthyosis Vulgaris</classLabel>
<newAxiom>&apos;Ichthyosis Vulgaris&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;FLG Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84779</classIRI>
<classLabel>X-Linked Ichthyosis</classLabel>
<newAxiom>&apos;X-Linked Ichthyosis&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;STS Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84764</classIRI>
<classLabel>HFE-Associated Hereditary Hemochromatosis</classLabel>
<newAxiom>&apos;HFE-Associated Hereditary Hemochromatosis&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;HFE Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84862</classIRI>
<classLabel>Glasdegib</classLabel>
<deletedAxiom>&apos;Glasdegib&apos; SubClassOf &apos;Signal Transduction Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Glasdegib&apos; SubClassOf &apos;Smoothened Antagonist&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84869</classIRI>
<classLabel>Malignant Hyperthermia Syndrome</classLabel>
<newAxiom>&apos;Malignant Hyperthermia Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;RYR1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84836</classIRI>
<classLabel>Hsp90 Inhibitor MPC-3100</classLabel>
<deletedAxiom>&apos;Hsp90 Inhibitor MPC-3100&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Hsp90 Inhibitor MPC-3100&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84806</classIRI>
<classLabel>Landau-Kleffner Syndrome</classLabel>
<newAxiom>&apos;Landau-Kleffner Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GRIN2A Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84987</classIRI>
<classLabel>Pallister-Hall Syndrome</classLabel>
<newAxiom>&apos;Pallister-Hall Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GLI3 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84957</classIRI>
<classLabel>Ornithine Carbamoyltransferase Deficiency Disease</classLabel>
<newAxiom>&apos;Ornithine Carbamoyltransferase Deficiency Disease&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;OTC Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84908</classIRI>
<classLabel>Multiple Sulfatase Deficiency Disease</classLabel>
<newAxiom>&apos;Multiple Sulfatase Deficiency Disease&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SUMF1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84903</classIRI>
<classLabel>Sly Syndrome</classLabel>
<newAxiom>&apos;Sly Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GUSB Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84904</classIRI>
<classLabel>Muenke Syndrome</classLabel>
<newAxiom>&apos;Muenke Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;FGFR3 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84902</classIRI>
<classLabel>Mucopolysaccharidosis Type IVB</classLabel>
<newAxiom>&apos;Mucopolysaccharidosis Type IVB&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GLB1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84927</classIRI>
<classLabel>Infantile Neuroaxonal Dystrophy</classLabel>
<newAxiom>&apos;Infantile Neuroaxonal Dystrophy&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;PLA2G6 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128802</classIRI>
<classLabel>Acrodermatitis Enteropathica</classLabel>
<newAxiom>&apos;Acrodermatitis Enteropathica&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SLC39A4 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C70912</classIRI>
<classLabel>Positive Air Pressure Device</classLabel>
<deletedAxiom>&apos;Positive Air Pressure Device&apos; SubClassOf &apos;Device&apos;</deletedAxiom>
<newAxiom>&apos;Positive Air Pressure Device&apos; SubClassOf &apos;Medical Device&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128555</classIRI>
<classLabel>Frameless Fractionated Stereotactic Radiation Therapy</classLabel>
<deletedAxiom>&apos;Frameless Fractionated Stereotactic Radiation Therapy&apos; SubClassOf &apos;Stereotactic Radiosurgery&apos;</deletedAxiom>
<newAxiom>&apos;Frameless Fractionated Stereotactic Radiation Therapy&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156862</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7691</classIRI>
<classLabel>Resectable Hepatocellular Carcinoma</classLabel>
<deletedAxiom>&apos;Resectable Hepatocellular Carcinoma&apos; EquivalentTo &apos;Resectable Carcinoma&apos; and &apos;Hepatocellular Carcinoma&apos; and &apos;Resectable Malignant Liver Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Resectable Hepatocellular Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156909 and &apos;Hepatocellular Carcinoma&apos; and &apos;Resectable Malignant Liver Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153360</classIRI>
<classLabel>Recurrent Bile Duct Carcinoma</classLabel>
<deletedAxiom>&apos;Recurrent Bile Duct Carcinoma&apos; EquivalentTo &apos;Bile Duct Carcinoma&apos; and &apos;Recurrent Digestive System Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Bile Duct Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156782 and &apos;Bile Duct Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7617</classIRI>
<classLabel>Benign Reproductive System Neoplasm</classLabel>
<deletedAxiom>&apos;Benign Reproductive System Neoplasm&apos; EquivalentTo &apos;Reproductive System Neoplasm&apos; and &apos;Benign Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Reproductive System&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Serous Adenocarcinoma Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Adenocarcinoma Cell with Intracytoplasmic Mucin&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Stromal Cell&apos;)</deletedAxiom>
<newAxiom>&apos;Benign Reproductive System Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156483 and &apos;Reproductive System Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Reproductive System&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Serous Adenocarcinoma Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Adenocarcinoma Cell with Intracytoplasmic Mucin&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Stromal Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153317</classIRI>
<classLabel>Advanced Unresectable Gastric Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Advanced Unresectable Gastric Adenocarcinoma&apos; EquivalentTo &apos;Advanced Carcinoma&apos; and &apos;Metastatic Unresectable Gastric Adenocarcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Unresectable Gastric Adenocarcinoma&apos; EquivalentTo &apos;Metastatic Unresectable Gastric Adenocarcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156746</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128115</classIRI>
<classLabel>Marshall Syndrome</classLabel>
<newAxiom>&apos;Marshall Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;COL11A1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7335</classIRI>
<classLabel>Reproductive Endocrine Neoplasm</classLabel>
<deletedAxiom>&apos;Reproductive Endocrine Neoplasm&apos; EquivalentTo &apos;Gonadal Disorder&apos; and &apos;Endocrine Neoplasm&apos; and &apos;Reproductive System Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Gonad&apos;) and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Reproductive System&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Sex Cord-Stromal Cell&apos;)</deletedAxiom>
<newAxiom>&apos;Reproductive Endocrine Neoplasm&apos; EquivalentTo &apos;Gonadal Disorder&apos; and &apos;Endocrine Neoplasm&apos; and &apos;Reproductive System Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Reproductive System&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Sex Cord-Stromal Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142173</classIRI>
<classLabel>Homocystinuria-Megaloblastic Anemia, cblE Complementation Type</classLabel>
<newAxiom>&apos;Homocystinuria-Megaloblastic Anemia, cblE Complementation Type&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MTRR Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C79835</classIRI>
<classLabel>Hsp90 Inhibitor XL888</classLabel>
<deletedAxiom>&apos;Hsp90 Inhibitor XL888&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Hsp90 Inhibitor XL888&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142085</classIRI>
<classLabel>Aromatic L-Amino-Acid Decarboxylase Deficiency</classLabel>
<newAxiom>&apos;Aromatic L-Amino-Acid Decarboxylase Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;DDC Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142084</classIRI>
<classLabel>Bleeding Disorder, Platelet-Type 17</classLabel>
<newAxiom>&apos;Bleeding Disorder, Platelet-Type 17&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GFI1B Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156360</classIRI>
<classLabel>Neuropathy, Hereditary Sensory and Autonomic, Type V</classLabel>
<newAxiom>&apos;Neuropathy, Hereditary Sensory and Autonomic, Type V&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;NGF Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156309</classIRI>
<classLabel>Mental Retardation, Autosomal Dominant 39</classLabel>
<newAxiom>&apos;Mental Retardation, Autosomal Dominant 39&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MYT1L Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156310</classIRI>
<classLabel>Spinal Muscular Atrophy Type 2</classLabel>
<newAxiom>&apos;Spinal Muscular Atrophy Type 2&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SMN1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99099</classIRI>
<classLabel>Type I Acrocephalosyndactyly</classLabel>
<newAxiom>&apos;Type I Acrocephalosyndactyly&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;FGFR2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99081</classIRI>
<classLabel>Arakawa Syndrome II</classLabel>
<newAxiom>&apos;Arakawa Syndrome II&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MTR Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99011</classIRI>
<classLabel>Pentalogy of Cantrell</classLabel>
<newAxiom>&apos;Pentalogy of Cantrell&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;PORCN Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156446</classIRI>
<classLabel>Epidermolysis Bullosa Dystrophica, Autosomal Recessive</classLabel>
<newAxiom>&apos;Epidermolysis Bullosa Dystrophica, Autosomal Recessive&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;COL7A1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156424</classIRI>
<classLabel>Hereditary Folate Malabsorption</classLabel>
<newAxiom>&apos;Hereditary Folate Malabsorption&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SLC46A1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156430</classIRI>
<classLabel>Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome 1</classLabel>
<newAxiom>&apos;Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;DNMT3B Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156433</classIRI>
<classLabel>Trichothiodystrophy 1, Photosensitive</classLabel>
<newAxiom>&apos;Trichothiodystrophy 1, Photosensitive&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ERCC2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156033</classIRI>
<classLabel>Rothmund Thomson Syndrome</classLabel>
<deletedAxiom>&apos;Rothmund Thomson Syndrome&apos; SubClassOf &apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;RECQL4 Gene Mutation&apos;</deletedAxiom>
<deletedAxiom>&apos;Rothmund Thomson Syndrome&apos; SubClassOf &apos;Syndrome&apos;</deletedAxiom>
<deletedAxiom>&apos;Rothmund Thomson Syndrome&apos; SubClassOf &apos;Genodermatosis&apos;</deletedAxiom>
<newAxiom>&apos;Rothmund Thomson Syndrome&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122657</classIRI>
<classLabel>LIG4 Syndrome</classLabel>
<newAxiom>&apos;LIG4 Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;LIG4 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122656</classIRI>
<classLabel>Cleft Lip/Palate-Ectodermal Dysplasia Syndrome</classLabel>
<newAxiom>&apos;Cleft Lip/Palate-Ectodermal Dysplasia Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;NECTIN1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C85036</classIRI>
<classLabel>Pseudoxanthoma Elasticum</classLabel>
<newAxiom>&apos;Pseudoxanthoma Elasticum&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ABCC6 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C85009</classIRI>
<classLabel>Piebaldism</classLabel>
<newAxiom>&apos;Piebaldism&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;KIT Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26798</classIRI>
<classLabel>Hypophosphatasia</classLabel>
<newAxiom>&apos;Hypophosphatasia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ALPL Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122436</classIRI>
<classLabel>Construction Trades Workers</classLabel>
<deletedAxiom>&apos;Construction Trades Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Construction Trades Workers&apos; SubClassOf &apos;Construction and Extraction Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122450</classIRI>
<classLabel>Extraction Workers</classLabel>
<deletedAxiom>&apos;Extraction Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Extraction Workers&apos; SubClassOf &apos;Construction and Extraction Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122462</classIRI>
<classLabel>Forest, Conservation, and Logging Workers</classLabel>
<deletedAxiom>&apos;Forest, Conservation, and Logging Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Forest, Conservation, and Logging Workers&apos; SubClassOf &apos;Farming, Fishing, and Forestry Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122459</classIRI>
<classLabel>Fishing and Hunting Workers</classLabel>
<deletedAxiom>&apos;Fishing and Hunting Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Fishing and Hunting Workers&apos; SubClassOf &apos;Farming, Fishing, and Forestry Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C85187</classIRI>
<classLabel>Thanatophoric Dysplasia</classLabel>
<newAxiom>&apos;Thanatophoric Dysplasia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;FGFR3 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C85182</classIRI>
<classLabel>Tangier Disease</classLabel>
<newAxiom>&apos;Tangier Disease&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ABCA1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C85233</classIRI>
<classLabel>Spinal and Bulbar Muscular Atrophy, X-linked 1</classLabel>
<newAxiom>&apos;Spinal and Bulbar Muscular Atrophy, X-linked 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;AR Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1462</classIRI>
<classLabel>Radicicol</classLabel>
<deletedAxiom>&apos;Radicicol&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Radicicol&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136464</classIRI>
<classLabel>Acrodysostosis 1</classLabel>
<newAxiom>&apos;Acrodysostosis 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;PRKAR1A Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C85454</classIRI>
<classLabel>Onalespib</classLabel>
<deletedAxiom>&apos;Onalespib&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Onalespib&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C756</classIRI>
<classLabel>Platinum</classLabel>
<deletedAxiom>&apos;Platinum&apos; SubClassOf &apos;Metal&apos;</deletedAxiom>
<newAxiom>&apos;Platinum&apos; SubClassOf &apos;Platinum-Group Metal&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1836</classIRI>
<classLabel>Radicicol 6-oxime</classLabel>
<deletedAxiom>&apos;Radicicol 6-oxime&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Radicicol 6-oxime&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C71467</classIRI>
<classLabel>Hsp90 Inhibitor AUY922</classLabel>
<deletedAxiom>&apos;Hsp90 Inhibitor AUY922&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Hsp90 Inhibitor AUY922&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142870</classIRI>
<classLabel>Advanced Bile Duct Carcinoma</classLabel>
<deletedAxiom>&apos;Advanced Bile Duct Carcinoma&apos; EquivalentTo &apos;Metastatic Bile Duct Carcinoma&apos; and &apos;Advanced Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Bile Duct Carcinoma&apos; EquivalentTo &apos;Metastatic Bile Duct Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156746</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142868</classIRI>
<classLabel>Advanced Microsatellite Stable Colorectal Carcinoma</classLabel>
<deletedAxiom>&apos;Advanced Microsatellite Stable Colorectal Carcinoma&apos; EquivalentTo &apos;Metastatic Microsatellite Stable Colorectal Carcinoma&apos; and &apos;Advanced Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Microsatellite Stable Colorectal Carcinoma&apos; EquivalentTo &apos;Metastatic Microsatellite Stable Colorectal Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156746</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142892</classIRI>
<classLabel>Familial Hypertrophic Cardiomyopathy Type 2</classLabel>
<newAxiom>&apos;Familial Hypertrophic Cardiomyopathy Type 2&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;TNNT2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91068</classIRI>
<classLabel>Hsp90 Inhibitor SNX-5422 Mesylate</classLabel>
<deletedAxiom>&apos;Hsp90 Inhibitor SNX-5422 Mesylate&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Hsp90 Inhibitor SNX-5422 Mesylate&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121945</classIRI>
<classLabel>Heritable Pulmonary Arterial Hypertension</classLabel>
<newAxiom>&apos;Heritable Pulmonary Arterial Hypertension&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;BMPR2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121639</classIRI>
<classLabel>EZH2 Inhibitor CPI-1205</classLabel>
<deletedAxiom>&apos;EZH2 Inhibitor CPI-1205&apos; SubClassOf &apos;Enzyme Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;EZH2 Inhibitor CPI-1205&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156804</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27393</classIRI>
<classLabel>Parathyroid Gland Oncocytic Adenoma</classLabel>
<deletedAxiom>&apos;Parathyroid Gland Oncocytic Adenoma&apos; EquivalentTo &apos;Oncocytic Adenoma&apos; and &apos;Parathyroid Gland Adenoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Oncocyte&apos;)</deletedAxiom>
<newAxiom>&apos;Parathyroid Gland Oncocytic Adenoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156757 and &apos;Oncocytic Adenoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Parathyroid Gland Oncocyte&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27326</classIRI>
<classLabel>Resectable Cholangiocarcinoma</classLabel>
<deletedAxiom>&apos;Resectable Cholangiocarcinoma&apos; EquivalentTo &apos;Resectable Carcinoma&apos; and &apos;Cholangiocarcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Resectable Cholangiocarcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156910 and &apos;Cholangiocarcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27599</classIRI>
<classLabel>Non-Neoplastic Urinary System Disorder</classLabel>
<deletedAxiom>&apos;Non-Neoplastic Urinary System Disorder&apos; SubClassOf &apos;Non-Neoplastic Disorder by Site&apos;</deletedAxiom>
<newAxiom>&apos;Non-Neoplastic Urinary System Disorder&apos; SubClassOf &apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Urinary System&apos;</newAxiom>
<newAxiom>&apos;Non-Neoplastic Urinary System Disorder&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156664</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27600</classIRI>
<classLabel>Non-Neoplastic Kidney Disorder</classLabel>
<newAxiom>&apos;Non-Neoplastic Kidney Disorder&apos; SubClassOf &apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Kidney&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27603</classIRI>
<classLabel>Non-Neoplastic Ureter Disorder</classLabel>
<newAxiom>&apos;Non-Neoplastic Ureter Disorder&apos; SubClassOf &apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Ureter&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27602</classIRI>
<classLabel>Non-Neoplastic Urethra Disorder</classLabel>
<newAxiom>&apos;Non-Neoplastic Urethra Disorder&apos; SubClassOf &apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Urethra&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27601</classIRI>
<classLabel>Non-Neoplastic Bladder Disorder</classLabel>
<newAxiom>&apos;Non-Neoplastic Bladder Disorder&apos; SubClassOf &apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bladder&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121564</classIRI>
<classLabel>Adenine Phosphoribosyltransferase Deficiency</classLabel>
<newAxiom>&apos;Adenine Phosphoribosyltransferase Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;APRT Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27611</classIRI>
<classLabel>Male Non-Neoplastic Reproductive System Disorder</classLabel>
<newAxiom>&apos;Male Non-Neoplastic Reproductive System Disorder&apos; SubClassOf &apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Male Reproductive System&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121563</classIRI>
<classLabel>Lysinuric Protein Intolerance</classLabel>
<newAxiom>&apos;Lysinuric Protein Intolerance&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SLC7A7 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27613</classIRI>
<classLabel>Non-Neoplastic Reproductive System Disorder</classLabel>
<deletedAxiom>&apos;Non-Neoplastic Reproductive System Disorder&apos; SubClassOf &apos;Non-Neoplastic Disorder by Site&apos;</deletedAxiom>
<newAxiom>&apos;Non-Neoplastic Reproductive System Disorder&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156664</newAxiom>
<newAxiom>&apos;Non-Neoplastic Reproductive System Disorder&apos; SubClassOf &apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Reproductive System&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27612</classIRI>
<classLabel>Female Non-Neoplastic Reproductive System Disorder</classLabel>
<newAxiom>&apos;Female Non-Neoplastic Reproductive System Disorder&apos; SubClassOf &apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Female Reproductive System&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27666</classIRI>
<classLabel>Non-Neoplastic Peritoneal Disorder</classLabel>
<newAxiom>&apos;Non-Neoplastic Peritoneal Disorder&apos; SubClassOf &apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Peritoneum&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27665</classIRI>
<classLabel>Non-Neoplastic Peritoneal and Retroperitoneal Disorder</classLabel>
<newAxiom>&apos;Non-Neoplastic Peritoneal and Retroperitoneal Disorder&apos; SubClassOf &apos;Disease_Has_Primary_Anatomic_Site&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156712</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27664</classIRI>
<classLabel>Peritoneal and Retroperitoneal Disorder</classLabel>
<deletedAxiom>&apos;Peritoneal and Retroperitoneal Disorder&apos; SubClassOf &apos;Disease_Has_Associated_Anatomic_Site&apos; some &apos;Abdomen&apos;</deletedAxiom>
<newAxiom>&apos;Peritoneal and Retroperitoneal Disorder&apos; SubClassOf &apos;Disease_Has_Associated_Anatomic_Site&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156712</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27668</classIRI>
<classLabel>Non-Neoplastic Retroperitoneal Disorder</classLabel>
<newAxiom>&apos;Non-Neoplastic Retroperitoneal Disorder&apos; SubClassOf &apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Retroperitoneum&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27814</classIRI>
<classLabel>Bile Duct Carcinoma</classLabel>
<deletedAxiom>&apos;Bile Duct Carcinoma&apos; EquivalentTo &apos;Bile Duct Neoplasm&apos; and &apos;Malignant Hepatobiliary Neoplasm&apos; and &apos;Digestive System Carcinoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bile Duct&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Bile Duct Epithelium&apos;)</deletedAxiom>
<newAxiom>&apos;Bile Duct Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156781 and &apos;Bile Duct Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bile Duct&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Bile Duct Epithelium&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102522</classIRI>
<classLabel>AT-Rich Interactive Domain-Containing Protein 1B</classLabel>
<deletedAxiom>&apos;AT-Rich Interactive Domain-Containing Protein 1B&apos; EquivalentTo &apos;Transcription Regulatory Protein&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;ARID Domain&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;hSWI/SNF&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Chromatin Remodeling Factor&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Regulation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Chromatin Remodeling&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ARID1B Gene&apos;)</deletedAxiom>
<newAxiom>&apos;AT-Rich Interactive Domain-Containing Protein 1B&apos; EquivalentTo &apos;Transcription Regulatory Protein&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;ARID Domain&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Chromatin Remodeling Factor&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Regulation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Chromatin Remodeling&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ARID1B Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9325</classIRI>
<classLabel>Adrenal Cortex Carcinoma</classLabel>
<deletedAxiom>&apos;Adrenal Cortex Carcinoma&apos; EquivalentTo &apos;Adenocarcinoma&apos; and &apos;Malignant Endocrine Neoplasm&apos; and &apos;Infrequent Neoplasm&apos; and &apos;Malignant Adrenal Cortex Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Adrenal Gland&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Adrenal Cortex&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Adrenal Cortical Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Adrenal Cortical Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Flank Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tumor Vascular Invasion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Capsular Invasion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abnormal Virilization&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Cushing Syndrome&apos;)</deletedAxiom>
<newAxiom>&apos;Adrenal Cortex Carcinoma&apos; EquivalentTo &apos;Adenocarcinoma&apos; and &apos;Malignant Endocrine Neoplasm&apos; and &apos;Infrequent Neoplasm&apos; and &apos;Malignant Adrenal Cortex Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Adrenal Gland&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Adrenal Cortex&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Adrenal Cortical Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Adrenal Cortical Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Flank Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tumor Vascular Invasion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Capsular Invasion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abnormal Virilization&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Cushing Syndrome&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CTNNB1 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CTNNB1 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9297</classIRI>
<classLabel>Malignant Urinary System Neoplasm</classLabel>
<deletedAxiom>&apos;Malignant Urinary System Neoplasm&apos; EquivalentTo &apos;Urinary System Neoplasm&apos; and &apos;Malignant Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Malignant Urinary System Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156484 and &apos;Urinary System Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116851</classIRI>
<classLabel>Hsp90 Inhibitor DS-2248</classLabel>
<deletedAxiom>&apos;Hsp90 Inhibitor DS-2248&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Hsp90 Inhibitor DS-2248&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116794</classIRI>
<classLabel>Blau Syndrome</classLabel>
<newAxiom>&apos;Blau Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;NOD2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C155870</classIRI>
<classLabel>Advanced Neuroendocrine Carcinoma</classLabel>
<deletedAxiom>&apos;Advanced Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Advanced Carcinoma&apos; and &apos;Metastatic Neuroendocrine Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Advanced Carcinoma&apos; and &apos;Metastatic Neuroendocrine Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156486</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C155856</classIRI>
<classLabel>MyPatientPal</classLabel>
<deletedAxiom>&apos;MyPatientPal&apos; SubClassOf &apos;Computer Program&apos;</deletedAxiom>
<newAxiom>&apos;MyPatientPal&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156877</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C155869</classIRI>
<classLabel>Metastatic Neuroendocrine Carcinoma</classLabel>
<deletedAxiom>&apos;Metastatic Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Metastatic Carcinoma&apos; and &apos;Neuroendocrine Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Neuroendocrine Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156485 and &apos;Metastatic Carcinoma&apos; and &apos;Neuroendocrine Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C155823</classIRI>
<classLabel>Kegel Nation App</classLabel>
<deletedAxiom>&apos;Kegel Nation App&apos; SubClassOf &apos;Applet&apos;</deletedAxiom>
<newAxiom>&apos;Kegel Nation App&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156877</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C141367</classIRI>
<classLabel>Xeroderma Pigmentosum Variant Type</classLabel>
<newAxiom>&apos;Xeroderma Pigmentosum Variant Type&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;POLH Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67493</classIRI>
<classLabel>Biliary Intraepithelial Neoplasia-3</classLabel>
<deletedAxiom>&apos;Biliary Intraepithelial Neoplasia-3&apos; EquivalentTo &apos;Digestive System Carcinoma In Situ&apos; and &apos;Biliary Intraepithelial Neoplasia&apos; and &apos;Grade III Glandular Intraepithelial Neoplasia&apos; and &apos;Malignant Hepatobiliary Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Biliary Intraepithelial Neoplasia-3&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156781 and &apos;Digestive System Carcinoma In Situ&apos; and &apos;Biliary Intraepithelial Neoplasia&apos; and &apos;Grade III Glandular Intraepithelial Neoplasia&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C155936</classIRI>
<classLabel>Metastatic Digestive System Neuroendocrine Carcinoma</classLabel>
<deletedAxiom>&apos;Metastatic Digestive System Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Metastatic Digestive System Carcinoma&apos; and &apos;Metastatic Neuroendocrine Carcinoma&apos; and &apos;Digestive System Neuroendocrine Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Digestive System Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Metastatic Digestive System Carcinoma&apos; and &apos;Metastatic Neuroendocrine Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156492 and &apos;Digestive System Neuroendocrine Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C92572</classIRI>
<classLabel>Hsp90 Inhibitor Debio 0932</classLabel>
<deletedAxiom>&apos;Hsp90 Inhibitor Debio 0932&apos; SubClassOf &apos;Heat Shock Protein Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Hsp90 Inhibitor Debio 0932&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157058</classIRI>
<classLabel>Anti-PD-L1/TIM-3 Bispecific Antibody LY3415244</classLabel>
<newAxiom>'Anti-PD-L1/TIM-3 Bispecific Antibody LY3415244' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157059</classIRI>
<classLabel>Germline APC Gene Mutation</classLabel>
<newAxiom>'Germline APC Gene Mutation' SubClassOf 'Germline Mutation'</newAxiom>
<newAxiom>'Germline APC Gene Mutation' SubClassOf 'APC Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157061</classIRI>
<classLabel>Anti-S15 Monoclonal Antibody NC318</classLabel>
<newAxiom>'Anti-S15 Monoclonal Antibody NC318' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-S15 Monoclonal Antibody NC318' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157062</classIRI>
<classLabel>Anti-DR5 Agonistic Monoclonal Antibody INBRX-109</classLabel>
<newAxiom>'Anti-DR5 Agonistic Monoclonal Antibody INBRX-109' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157060</classIRI>
<classLabel>Suspicion of Metastasis</classLabel>
<newAxiom>'Suspicion of Metastasis' SubClassOf 'Suspicion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157036</classIRI>
<classLabel>Zero to Ten Seconds Walking</classLabel>
<newAxiom>'Zero to Ten Seconds Walking' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157037</classIRI>
<classLabel>Eleven to Twenty Seconds Walking</classLabel>
<newAxiom>'Eleven to Twenty Seconds Walking' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157038</classIRI>
<classLabel>Greater Than Twenty Seconds Walking, or Patient Unwilling, or Requires Assistance Walking</classLabel>
<newAxiom>'Greater Than Twenty Seconds Walking, or Patient Unwilling, or Requires Assistance Walking' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157039</classIRI>
<classLabel>PK-R Allosteric Activator AG-348</classLabel>
<newAxiom>'PK-R Allosteric Activator AG-348' SubClassOf 'Agent Affecting Blood or Body Fluid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157040</classIRI>
<classLabel>GSR Gene</classLabel>
<newAxiom>'GSR Gene' SubClassOf 'Oxidoreductase Gene'</newAxiom>
<newAxiom>'GSR Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Homeostatic Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157041</classIRI>
<classLabel>GSR wt Allele</classLabel>
<newAxiom>'GSR wt Allele' EquivalentTo 'GSR Gene' and ('Gene_Is_Element_In_Pathway' some 'Glutathione Metabolism Pathway') and ('Gene_Is_Element_In_Pathway' some 'Free Radical Induced Apoptosis Pathway') and ('Gene_In_Chromosomal_Location' some '8p12')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157042</classIRI>
<classLabel>Glutathione Reductase, Mitochondrial</classLabel>
<newAxiom>'Glutathione Reductase, Mitochondrial' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'GSR Gene'</newAxiom>
<newAxiom>'Glutathione Reductase, Mitochondrial' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Mitochondrion'</newAxiom>
<newAxiom>'Glutathione Reductase, Mitochondrial' SubClassOf 'Gene_Product_Is_Element_In_Pathway' some 'Free Radical Induced Apoptosis Pathway'</newAxiom>
<newAxiom>'Glutathione Reductase, Mitochondrial' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Homeostatic Process'</newAxiom>
<newAxiom>'Glutathione Reductase, Mitochondrial' SubClassOf 'Gene_Product_Is_Element_In_Pathway' some 'Glutathione Metabolism Pathway'</newAxiom>
<newAxiom>'Glutathione Reductase, Mitochondrial' SubClassOf 'Oxidoreductase'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157043</classIRI>
<classLabel>SRXN1 Gene</classLabel>
<newAxiom>'SRXN1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cellular Stress Response'</newAxiom>
<newAxiom>'SRXN1 Gene' SubClassOf 'Oxidoreductase Gene'</newAxiom>
<newAxiom>'SRXN1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Oxidative Stress'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157044</classIRI>
<classLabel>SRXN1 wt Allele</classLabel>
<newAxiom>'SRXN1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '20p13'</newAxiom>
<newAxiom>'SRXN1 wt Allele' SubClassOf 'SRXN1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157045</classIRI>
<classLabel>Sulfiredoxin-1</classLabel>
<newAxiom>'Sulfiredoxin-1' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'SRXN1 Gene'</newAxiom>
<newAxiom>'Sulfiredoxin-1' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Oxidative Stress'</newAxiom>
<newAxiom>'Sulfiredoxin-1' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Cellular Stress Response'</newAxiom>
<newAxiom>'Sulfiredoxin-1' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Cytoplasm'</newAxiom>
<newAxiom>'Sulfiredoxin-1' SubClassOf 'Oxidoreductase'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157046</classIRI>
<classLabel>GPAT3 Gene</classLabel>
<newAxiom>'GPAT3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Phospholipid Metabolism'</newAxiom>
<newAxiom>'GPAT3 Gene' SubClassOf 'Transferase Gene'</newAxiom>
<newAxiom>'GPAT3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Triglyceride Metabolism'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157047</classIRI>
<classLabel>GPAT3 wt Allele</classLabel>
<newAxiom>'GPAT3 wt Allele' SubClassOf 'GPAT3 Gene'</newAxiom>
<newAxiom>'GPAT3 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Glycerophospholipid Metabolism Pathway'</newAxiom>
<newAxiom>'GPAT3 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Glycerolipid Metabolism Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157048</classIRI>
<classLabel>Glycerol-3-Phosphate Acyltransferase 3</classLabel>
<newAxiom>'Glycerol-3-Phosphate Acyltransferase 3' EquivalentTo 'Acyltransferase' and ('Gene_Product_Is_Element_In_Pathway' some 'Glycerolipid Metabolism Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Glycerophospholipid Metabolism Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Rough Endoplasmic Reticulum') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Smooth Endoplasmic Reticulum') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Phospholipid Metabolism') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Triglyceride Metabolism') and ('Gene_Product_Encoded_By_Gene' some 'GPAT3 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157049</classIRI>
<classLabel>Pen Device</classLabel>
<newAxiom>'Pen Device' SubClassOf 'Medical Device'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157051</classIRI>
<classLabel>Ipilimumab/Talimogene Laherparepvec Regimen</classLabel>
<newAxiom>'Ipilimumab/Talimogene Laherparepvec Regimen' SubClassOf 'Chemotherapy Regimen Used to Treat Melanoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157052</classIRI>
<classLabel>LUM Imaging System</classLabel>
<newAxiom>'LUM Imaging System' SubClassOf 'Imaging System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157053</classIRI>
<classLabel>LUM Imaging Device</classLabel>
<newAxiom>'LUM Imaging Device' SubClassOf 'Imaging Device'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157054</classIRI>
<classLabel>Incisional Vacuum-Assisted Closure Therapy</classLabel>
<newAxiom>'Incisional Vacuum-Assisted Closure Therapy' SubClassOf 'Post-operative Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157055</classIRI>
<classLabel>Hormone Receptor Positive</classLabel>
<newAxiom>'Hormone Receptor Positive' SubClassOf 'Hormone Receptor/HER2 Positive'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157056</classIRI>
<classLabel>Hormone Receptor Positive Breast Carcinoma</classLabel>
<newAxiom>'Hormone Receptor Positive Breast Carcinoma' EquivalentTo 'Breast Carcinoma' and ('Disease_Has_Finding' some 'Hormone Receptor Positive')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157057</classIRI>
<classLabel>Refractory Hormone Receptor Positive Breast Carcinoma</classLabel>
<newAxiom>'Refractory Hormone Receptor Positive Breast Carcinoma' EquivalentTo 'Refractory Breast Carcinoma' and 'Hormone Receptor Positive Breast Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157014</classIRI>
<classLabel>Activities that Require Help</classLabel>
<newAxiom>'Activities that Require Help' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157015</classIRI>
<classLabel>When Help is Needed Can Count on Someone Willing and Able to Meet Needs</classLabel>
<newAxiom>'When Help is Needed Can Count on Someone Willing and Able to Meet Needs' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157016</classIRI>
<classLabel>Use Five or More Different Prescription Medications Regularly</classLabel>
<newAxiom>'Use Five or More Different Prescription Medications Regularly' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157017</classIRI>
<classLabel>Sometimes Forget to Take Prescription Medications</classLabel>
<newAxiom>'Sometimes Forget to Take Prescription Medications' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157018</classIRI>
<classLabel>Have Recently Lost Weight and Clothing Has Become Looser</classLabel>
<newAxiom>'Have Recently Lost Weight and Clothing Has Become Looser' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157019</classIRI>
<classLabel>Often Feel Sad or Depressed</classLabel>
<newAxiom>'Often Feel Sad or Depressed' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157020</classIRI>
<classLabel>Have Urinary Incontinence</classLabel>
<newAxiom>'Have Urinary Incontinence' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157021</classIRI>
<classLabel>Timed Get Up and Go Test</classLabel>
<newAxiom>'Timed Get Up and Go Test' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157022</classIRI>
<classLabel>Final Score Equals Sum of Column Totals</classLabel>
<newAxiom>'Final Score Equals Sum of Column Totals' SubClassOf 'Score'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157023</classIRI>
<classLabel>No Spacing Errors</classLabel>
<newAxiom>'No Spacing Errors' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157025</classIRI>
<classLabel>L-lysine/L-arginine-containing Amino Acid</classLabel>
<newAxiom>'L-lysine/L-arginine-containing Amino Acid' SubClassOf 'Nephroprotective Agent'</newAxiom>
<newAxiom>'L-lysine/L-arginine-containing Amino Acid' SubClassOf 'Radioprotective Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157026</classIRI>
<classLabel>Other Errors</classLabel>
<newAxiom>'Other Errors' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157027</classIRI>
<classLabel>No Hospital Admission</classLabel>
<newAxiom>'No Hospital Admission' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157028</classIRI>
<classLabel>One or Two Hospital Admissions</classLabel>
<newAxiom>'One or Two Hospital Admissions' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157029</classIRI>
<classLabel>Two or More Hospital Admissions</classLabel>
<newAxiom>'Two or More Hospital Admissions' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157030</classIRI>
<classLabel>Excellent, Very Good, or Good Health</classLabel>
<newAxiom>'Excellent, Very Good, or Good Health' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157031</classIRI>
<classLabel>Fair Health</classLabel>
<newAxiom>'Fair Health' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157032</classIRI>
<classLabel>Poor Health</classLabel>
<newAxiom>'Poor Health' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157033</classIRI>
<classLabel>Zero or One Activity Required Help</classLabel>
<newAxiom>'Zero or One Activity Required Help' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157034</classIRI>
<classLabel>Two to Four Activities Required Help</classLabel>
<newAxiom>'Two to Four Activities Required Help' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157035</classIRI>
<classLabel>Five to Eight Activities Required Help</classLabel>
<newAxiom>'Five to Eight Activities Required Help' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157000</classIRI>
<classLabel>Do Aerobics or Aerobic Dancing</classLabel>
<newAxiom>'Do Aerobics or Aerobic Dancing' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157001</classIRI>
<classLabel>Do Moderate to Heavy Strength Training</classLabel>
<newAxiom>'Do Moderate to Heavy Strength Training' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157002</classIRI>
<classLabel>Do Light Strength Training</classLabel>
<newAxiom>'Do Light Strength Training' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157003</classIRI>
<classLabel>Do General Conditioning Exercises</classLabel>
<newAxiom>'Do General Conditioning Exercises' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157004</classIRI>
<classLabel>Play Basketball, Soccer, or Racquetball</classLabel>
<newAxiom>'Play Basketball, Soccer, or Racquetball' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157005</classIRI>
<classLabel>Do Other Physical Activity</classLabel>
<newAxiom>'Do Other Physical Activity' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157006</classIRI>
<classLabel>Other Physical Activity</classLabel>
<newAxiom>'Other Physical Activity' SubClassOf 'Physical Activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157007</classIRI>
<classLabel>Activity Hours per Week</classLabel>
<newAxiom>'Activity Hours per Week' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157008</classIRI>
<classLabel>Coke Oven Emission Exposure</classLabel>
<newAxiom>'Coke Oven Emission Exposure' SubClassOf 'Occupational Exposure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157009</classIRI>
<classLabel>Heavy Metal Mining</classLabel>
<newAxiom>'Heavy Metal Mining' SubClassOf 'Hard Rock Mining'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157010</classIRI>
<classLabel>Paint</classLabel>
<newAxiom>'Paint' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157011</classIRI>
<classLabel>Edmonton Frail Scale</classLabel>
<newAxiom>'Edmonton Frail Scale' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157012</classIRI>
<classLabel>Cognition Clock Test</classLabel>
<newAxiom>'Cognition Clock Test' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157013</classIRI>
<classLabel>Times Admitted to a Hospital</classLabel>
<newAxiom>'Times Admitted to a Hospital' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156768</classIRI>
<classLabel>Malignant Basal Cell</classLabel>
<newAxiom>'Malignant Basal Cell' SubClassOf 'Malignant Basaloid Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156767</classIRI>
<classLabel>Basal Cell Carcinoma</classLabel>
<newAxiom>'Basal Cell Carcinoma' EquivalentTo 'Carcinoma' and 'Malignant Basal Cell Neoplasm' and ('Disease_Has_Abnormal_Cell' some 'Malignant Basal Cell')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156766</classIRI>
<classLabel>Meclinertant</classLabel>
<newAxiom>'Meclinertant' SubClassOf 'Agent Affecting Nervous System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156765</classIRI>
<classLabel>Static Imaging</classLabel>
<newAxiom>'Static Imaging' SubClassOf 'Imaging Technique'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156764</classIRI>
<classLabel>HER2/Neu Low Expression</classLabel>
<newAxiom>'HER2/Neu Low Expression' SubClassOf 'HER2/Neu Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156763</classIRI>
<classLabel>MDM4 Gene Amplification</classLabel>
<newAxiom>'MDM4 Gene Amplification' SubClassOf 'Gene Amplification Abnormality'</newAxiom>
<newAxiom>'MDM4 Gene Amplification' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'MDM4 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156762</classIRI>
<classLabel>PPM1D Gene Amplification</classLabel>
<newAxiom>'PPM1D Gene Amplification' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'PPM1D Gene'</newAxiom>
<newAxiom>'PPM1D Gene Amplification' SubClassOf 'Gene Amplification Abnormality'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156761</classIRI>
<classLabel>Activating PPM1D Gene Mutation</classLabel>
<newAxiom>'Activating PPM1D Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'PPM1D Gene'</newAxiom>
<newAxiom>'Activating PPM1D Gene Mutation' SubClassOf 'PPM1D Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156769</classIRI>
<classLabel>Metastatic Basal Cell Carcinoma</classLabel>
<newAxiom>'Metastatic Basal Cell Carcinoma' EquivalentTo 'Basal Cell Carcinoma' and 'Metastatic Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156771</classIRI>
<classLabel>Biochemically Recurrent Prostate Carcinoma</classLabel>
<newAxiom>'Biochemically Recurrent Prostate Carcinoma' EquivalentTo 'Recurrent Prostate Carcinoma' and ('Disease_Has_Finding' some 'PSA Failure')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156770</classIRI>
<classLabel>Locally Advanced Basal Cell Carcinoma</classLabel>
<newAxiom>'Locally Advanced Basal Cell Carcinoma' EquivalentTo 'Locally Advanced Carcinoma' and 'Metastatic Basal Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156779</classIRI>
<classLabel>Entity With Role in Clinical Study</classLabel>
<newAxiom>'Entity With Role in Clinical Study' SubClassOf 'Person'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156778</classIRI>
<classLabel>Vision Assessment</classLabel>
<newAxiom>'Vision Assessment' SubClassOf 'Eye Examination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156777</classIRI>
<classLabel>Dihydroorotate Dehydrogenase Inhibitor ASLAN003</classLabel>
<newAxiom>'Dihydroorotate Dehydrogenase Inhibitor ASLAN003' SubClassOf 'Immunosuppressant'</newAxiom>
<newAxiom>'Dihydroorotate Dehydrogenase Inhibitor ASLAN003' SubClassOf 'Dihydroorotate Dehydrogenase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156776</classIRI>
<classLabel>Cognitive Electrophysiology Assessment</classLabel>
<newAxiom>'Cognitive Electrophysiology Assessment' SubClassOf 'Cognitive Assessment'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156775</classIRI>
<classLabel>Neurocognitive Assessment</classLabel>
<newAxiom>'Neurocognitive Assessment' SubClassOf 'Cognitive Assessment'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156774</classIRI>
<classLabel>JAK1 Inhibitor AZD4205</classLabel>
<newAxiom>'JAK1 Inhibitor AZD4205' SubClassOf 'Tyrosine Kinase Inhibitor'</newAxiom>
<newAxiom>'JAK1 Inhibitor AZD4205' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156773</classIRI>
<classLabel>EGFR Mutant-specific Inhibitor D-0316</classLabel>
<newAxiom>'EGFR Mutant-specific Inhibitor D-0316' SubClassOf 'Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor'</newAxiom>
<newAxiom>'EGFR Mutant-specific Inhibitor D-0316' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156772</classIRI>
<classLabel>Copper Cu 64-CB-TE1A1P-PEG4-LLP2A</classLabel>
<newAxiom>'Copper Cu 64-CB-TE1A1P-PEG4-LLP2A' SubClassOf 'Radioconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156782</classIRI>
<classLabel>Recurrent Biliary Tract Carcinoma</classLabel>
<newAxiom>'Recurrent Biliary Tract Carcinoma' EquivalentTo 'Biliary Tract Carcinoma' and 'Recurrent Digestive System Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156781</classIRI>
<classLabel>Biliary Tract Carcinoma</classLabel>
<newAxiom>'Biliary Tract Carcinoma' EquivalentTo 'Malignant Hepatobiliary Neoplasm' and 'Digestive System Carcinoma' and ('Disease_Has_Primary_Anatomic_Site' some 'Biliary Tract')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156746</classIRI>
<classLabel>Advanced Digestive System Carcinoma</classLabel>
<newAxiom>'Advanced Digestive System Carcinoma' EquivalentTo 'Metastatic Digestive System Carcinoma' and 'Advanced Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156745</classIRI>
<classLabel>Locally Advanced Microsatellite Stable Colorectal Carcinoma</classLabel>
<newAxiom>'Locally Advanced Microsatellite Stable Colorectal Carcinoma' EquivalentTo 'Metastatic Microsatellite Stable Colorectal Carcinoma' and 'Locally Advanced Digestive System Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156744</classIRI>
<classLabel>CYP11A1 inhibitor ODM-208</classLabel>
<newAxiom>'CYP11A1 inhibitor ODM-208' SubClassOf 'Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156743</classIRI>
<classLabel>EZH2 Inhibitor PF-06821497</classLabel>
<newAxiom>'EZH2 Inhibitor PF-06821497' SubClassOf 'EZH2 Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156742</classIRI>
<classLabel>Carbon C 11-osimertinib</classLabel>
<newAxiom>'Carbon C 11-osimertinib' SubClassOf 'Radioconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156741</classIRI>
<classLabel>Anti-PD-L1 Monoclonal Antibody BCD-135</classLabel>
<newAxiom>'Anti-PD-L1 Monoclonal Antibody BCD-135' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-PD-L1 Monoclonal Antibody BCD-135' SubClassOf 'Anti-PD-L1 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156740</classIRI>
<classLabel>MCL-1 inhibitor AMG 397</classLabel>
<newAxiom>'MCL-1 inhibitor AMG 397' SubClassOf 'Mcl-1 Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156749</classIRI>
<classLabel>Melanoma Risk Factor</classLabel>
<newAxiom>'Melanoma Risk Factor' SubClassOf 'Risk Factor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156748</classIRI>
<classLabel>Millimeter-Wave Holographic Imaging</classLabel>
<newAxiom>'Millimeter-Wave Holographic Imaging' SubClassOf 'Imaging Technique'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156747</classIRI>
<classLabel>AssureMDx</classLabel>
<newAxiom>'AssureMDx' SubClassOf 'Molecular Analysis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156757</classIRI>
<classLabel>Benign Parathyroid Gland Adenoma</classLabel>
<newAxiom>'Benign Parathyroid Gland Adenoma' EquivalentTo 'Benign Parathyroid Gland Neoplasm' and 'Parathyroid Gland Adenoma' and 'Benign Endocrine Neoplasm' and ('Disease_Excludes_Finding' some 'Mitotic Activity') and ('Disease_Excludes_Finding' some 'Hemosiderin Deposition') and ('Disease_Excludes_Finding' some 'Broad Fibrous Bands Formation')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156756</classIRI>
<classLabel>bRaf/cRaf Dimer</classLabel>
<newAxiom>'bRaf/cRaf Dimer' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156755</classIRI>
<classLabel>Raf/KSR/Mek1 Trimer</classLabel>
<newAxiom>'Raf/KSR/Mek1 Trimer' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156754</classIRI>
<classLabel>Proximity Ligation Assay</classLabel>
<newAxiom>'Proximity Ligation Assay' SubClassOf 'Protein Analysis'</newAxiom>
<newAxiom>'Proximity Ligation Assay' SubClassOf 'In Vitro Assay'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156753</classIRI>
<classLabel>Neoplastic Plasma Cells 10-59 Percent of Bone Marrow Nucleated Cells</classLabel>
<newAxiom>'Neoplastic Plasma Cells 10-59 Percent of Bone Marrow Nucleated Cells' SubClassOf 'Neoplastic Plasma Cells 10-60 Percent of Bone Marrow Nucleated Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156752</classIRI>
<classLabel>SDHB Negative</classLabel>
<newAxiom>'SDHB Negative' SubClassOf 'Negative Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156751</classIRI>
<classLabel>TNFAIP3 Gene Mutation</classLabel>
<newAxiom>'TNFAIP3 Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'TNFAIP3 Gene'</newAxiom>
<newAxiom>'TNFAIP3 Gene Mutation' SubClassOf 'Gene Mutant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156750</classIRI>
<classLabel>PPP2R2A Gene Mutation</classLabel>
<newAxiom>'PPP2R2A Gene Mutation' SubClassOf 'Gene Mutant'</newAxiom>
<newAxiom>'PPP2R2A Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'PPP2R2A Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156759</classIRI>
<classLabel>PRMT1 Inhibitor GSK3368715</classLabel>
<newAxiom>'PRMT1 Inhibitor GSK3368715' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156758</classIRI>
<classLabel>RELA Fusion Positive</classLabel>
<newAxiom>'RELA Fusion Positive' SubClassOf 'Positive Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156760</classIRI>
<classLabel>PPM1D Gene Mutation</classLabel>
<newAxiom>'PPM1D Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'PPM1D Gene'</newAxiom>
<newAxiom>'PPM1D Gene Mutation' SubClassOf 'Gene Mutant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156724</classIRI>
<classLabel>Acute Myeloid Leukemia with Multilineage Dysplasia in Remission</classLabel>
<newAxiom>'Acute Myeloid Leukemia with Multilineage Dysplasia in Remission' SubClassOf 'Acute Myeloid Leukemia in Remission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156723</classIRI>
<classLabel>Recurrent Acute Erythroid Leukemia</classLabel>
<newAxiom>'Recurrent Acute Erythroid Leukemia' EquivalentTo 'Recurrent Acute Myeloid Leukemia Not Otherwise Specified' and 'Acute Erythroid Leukemia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156722</classIRI>
<classLabel>Recurrent Acute Monoblastic and Monocytic Leukemia</classLabel>
<newAxiom>'Recurrent Acute Monoblastic and Monocytic Leukemia' EquivalentTo 'Recurrent Acute Myeloid Leukemia Not Otherwise Specified' and 'Acute Monoblastic and Monocytic Leukemia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156721</classIRI>
<classLabel>Total Lymphoid Irradiation</classLabel>
<newAxiom>'Total Lymphoid Irradiation' SubClassOf 'Extensive Radiation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156720</classIRI>
<classLabel>Recurrent Acute Myeloid Leukemia with Multilineage Dysplasia</classLabel>
<newAxiom>'Recurrent Acute Myeloid Leukemia with Multilineage Dysplasia' EquivalentTo 'Recurrent Acute Myeloid Leukemia with Myelodysplasia-Related Changes' and 'Acute Myeloid Leukemia with Multilineage Dysplasia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156729</classIRI>
<classLabel>ALK-2 Inhibitor TP-0184</classLabel>
<newAxiom>'ALK-2 Inhibitor TP-0184' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'ALK-2 Inhibitor TP-0184' SubClassOf 'Serine/Threonine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156728</classIRI>
<classLabel>Sodium-Potassium Adenosine Triphosphatase Inhibitor RX108</classLabel>
<newAxiom>'Sodium-Potassium Adenosine Triphosphatase Inhibitor RX108' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'Sodium-Potassium Adenosine Triphosphatase Inhibitor RX108' SubClassOf 'Antineoplastic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156726</classIRI>
<classLabel>Anti-PD-1 Monoclonal Antibody CS1003</classLabel>
<newAxiom>'Anti-PD-1 Monoclonal Antibody CS1003' SubClassOf 'Anti-PD1 Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-PD-1 Monoclonal Antibody CS1003' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156725</classIRI>
<classLabel>Acute Monoblastic and Monocytic Leukemia in Remission</classLabel>
<newAxiom>'Acute Monoblastic and Monocytic Leukemia in Remission' SubClassOf 'Acute Myeloid Leukemia in Remission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156735</classIRI>
<classLabel>SERD D-0502</classLabel>
<newAxiom>'SERD D-0502' SubClassOf 'Selective Estrogen Receptor Down Regulator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156734</classIRI>
<classLabel>Anti-CTLA-4 Monoclonal Antibody BCD-145</classLabel>
<newAxiom>'Anti-CTLA-4 Monoclonal Antibody BCD-145' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-CTLA-4 Monoclonal Antibody BCD-145' SubClassOf 'Anti-CTLA-4 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156733</classIRI>
<classLabel>MARCKS Protein Inhibitor BIO-11006</classLabel>
<newAxiom>'MARCKS Protein Inhibitor BIO-11006' SubClassOf 'Antineoplastic Biological Agent'</newAxiom>
<newAxiom>'MARCKS Protein Inhibitor BIO-11006' SubClassOf 'Antineoplastic Protein Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156732</classIRI>
<classLabel>EGFR Antisense DNA BB-401</classLabel>
<newAxiom>'EGFR Antisense DNA BB-401' SubClassOf 'Antisense Oligonucleotides'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156731</classIRI>
<classLabel>Recurrent Acute Megakaryoblastic Leukemia</classLabel>
<newAxiom>'Recurrent Acute Megakaryoblastic Leukemia' EquivalentTo 'Recurrent Acute Myeloid Leukemia Not Otherwise Specified' and 'Acute Megakaryoblastic Leukemia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156730</classIRI>
<classLabel>Navarixin</classLabel>
<newAxiom>'Navarixin' SubClassOf 'Chemokine Receptor Antagonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156739</classIRI>
<classLabel>Zirconium Zr 89-DFO-cRGDY PEG-Cy5-C' Dots</classLabel>
<newAxiom>'Zirconium Zr 89-DFO-cRGDY PEG-Cy5-C' Dots' SubClassOf 'Radioimmunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156738</classIRI>
<classLabel>Anti-PD-1 Monoclonal Antibody HLX10</classLabel>
<newAxiom>'Anti-PD-1 Monoclonal Antibody HLX10' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-PD-1 Monoclonal Antibody HLX10' SubClassOf 'Anti-PD1 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156737</classIRI>
<classLabel>RIPK1 Inhibitor GSK3145095</classLabel>
<newAxiom>'RIPK1 Inhibitor GSK3145095' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156736</classIRI>
<classLabel>Fermented Prebiotic Dietary Supplement AferBio</classLabel>
<newAxiom>'Fermented Prebiotic Dietary Supplement AferBio' SubClassOf 'Dietary Supplement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156702</classIRI>
<classLabel>Para-toluenesulfonamide</classLabel>
<newAxiom>'Para-toluenesulfonamide' SubClassOf 'Apoptotic Pathway-targeting Antineoplastic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156701</classIRI>
<classLabel>Porcupine Inhibitor RXC004</classLabel>
<newAxiom>'Porcupine Inhibitor RXC004' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156700</classIRI>
<classLabel>Glumetinib</classLabel>
<newAxiom>'Glumetinib' SubClassOf 'c-Met Inhibitor'</newAxiom>
<newAxiom>'Glumetinib' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156709</classIRI>
<classLabel>MDM2 Inhibitor BI 907828</classLabel>
<newAxiom>'MDM2 Inhibitor BI 907828' SubClassOf 'Apoptotic Pathway-targeting Antineoplastic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156708</classIRI>
<classLabel>eHealth for Sedentary Behavior</classLabel>
<newAxiom>'eHealth for Sedentary Behavior' SubClassOf 'Behavioral, Psychological or Informational Intervention'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156707</classIRI>
<classLabel>Anti-GCC Antibody-Drug Conjugate TAK-164</classLabel>
<newAxiom>'Anti-GCC Antibody-Drug Conjugate TAK-164' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
<newAxiom>'Anti-GCC Antibody-Drug Conjugate TAK-164' SubClassOf 'Immunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156706</classIRI>
<classLabel>Autologous Anti-BCMA-CAR-mRNA-transfected CD8+ T-lymphocytes</classLabel>
<newAxiom>'Autologous Anti-BCMA-CAR-mRNA-transfected CD8+ T-lymphocytes' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous Anti-BCMA-CAR-mRNA-transfected CD8+ T-lymphocytes' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous Anti-BCMA-CAR-mRNA-transfected CD8+ T-lymphocytes' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156705</classIRI>
<classLabel>Anti-HER2/Anti-CD3 Bispecific Monoclonal Antibody BTRC 4017A</classLabel>
<newAxiom>'Anti-HER2/Anti-CD3 Bispecific Monoclonal Antibody BTRC 4017A' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-HER2/Anti-CD3 Bispecific Monoclonal Antibody BTRC 4017A' SubClassOf 'Anti-HER2 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156703</classIRI>
<classLabel>Fine Motor Skills</classLabel>
<newAxiom>'Fine Motor Skills' SubClassOf 'Personal Attribute'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156713</classIRI>
<classLabel>Benign Peritoneal and Retroperitoneal Neoplasm</classLabel>
<newAxiom>'Benign Peritoneal and Retroperitoneal Neoplasm' EquivalentTo 'Benign Neoplasm' and 'Peritoneal and Retroperitoneal Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Peritoneum and Retroperitoneum')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156712</classIRI>
<classLabel>Peritoneum and Retroperitoneum</classLabel>
<newAxiom>'Peritoneum and Retroperitoneum' SubClassOf 'Other Anatomic Concept'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156711</classIRI>
<classLabel>Malignant Peritoneal and Retroperitoneal Neoplasm</classLabel>
<newAxiom>'Malignant Peritoneal and Retroperitoneal Neoplasm' EquivalentTo 'Peritoneal and Retroperitoneal Neoplasm' and 'Malignant Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156710</classIRI>
<classLabel>Goserelin Acetate Extended-release Microspheres LY01005</classLabel>
<newAxiom>'Goserelin Acetate Extended-release Microspheres LY01005' SubClassOf 'Gonadotropin-releasing Hormone Analog'</newAxiom>
<newAxiom>'Goserelin Acetate Extended-release Microspheres LY01005' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Androgen Activity Inhibition'</newAxiom>
<newAxiom>'Goserelin Acetate Extended-release Microspheres LY01005' SubClassOf 'Chemical_Or_Drug_Has_Mechanism_Of_Action' some 'Receptor Activation Process'</newAxiom>
<newAxiom>'Goserelin Acetate Extended-release Microspheres LY01005' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Endocrine Secretory Inhibition'</newAxiom>
<newAxiom>'Goserelin Acetate Extended-release Microspheres LY01005' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Estrogen Activity Inhibition'</newAxiom>
<newAxiom>'Goserelin Acetate Extended-release Microspheres LY01005' SubClassOf 'Chemical_Or_Drug_Affects_Gene_Product' some 'Gonadotropin-Releasing Hormone Receptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156719</classIRI>
<classLabel>Recurrent Acute Myeloid Leukemia with t (9;11) (p21.3; q23.3); MLLT3-KMT2A</classLabel>
<newAxiom>'Recurrent Acute Myeloid Leukemia with t (9;11) (p21.3; q23.3); MLLT3-KMT2A' EquivalentTo 'Recurrent Acute Myeloid Leukemia with Recurrent Genetic Abnormalities' and 'Acute Myeloid Leukemia with t(9;11)(p21.3;q23.3); MLLT3-KMT2A'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156718</classIRI>
<classLabel>Recurrent Acute Myeloid Leukemia with Recurrent Genetic Abnormalities</classLabel>
<newAxiom>'Recurrent Acute Myeloid Leukemia with Recurrent Genetic Abnormalities' EquivalentTo 'Recurrent Acute Myeloid Leukemia' and 'Acute Myeloid Leukemia with Recurrent Genetic Abnormalities'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156717</classIRI>
<classLabel>Recurrent Acute Myelomonocytic Leukemia</classLabel>
<newAxiom>'Recurrent Acute Myelomonocytic Leukemia' EquivalentTo 'Recurrent Acute Myeloid Leukemia Not Otherwise Specified' and 'Acute Myelomonocytic Leukemia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156716</classIRI>
<classLabel>Recurrent Acute Myeloid Leukemia Not Otherwise Specified</classLabel>
<newAxiom>'Recurrent Acute Myeloid Leukemia Not Otherwise Specified' EquivalentTo 'Recurrent Acute Myeloid Leukemia' and 'Acute Myeloid Leukemia Not Otherwise Specified'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156715</classIRI>
<classLabel>Malignant Pelvic Neoplasm</classLabel>
<newAxiom>'Malignant Pelvic Neoplasm' EquivalentTo 'Malignant Neoplasm' and ('Disease_Has_Associated_Anatomic_Site' some 'Pelvis')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156714</classIRI>
<classLabel>Malignant Abdominal Neoplasm</classLabel>
<newAxiom>'Malignant Abdominal Neoplasm' EquivalentTo 'Malignant Neoplasm' and ('Disease_Has_Associated_Anatomic_Site' some 'Abdomen')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156789</classIRI>
<classLabel>Locally Advanced Unresectable Basal Cell Carcinoma</classLabel>
<newAxiom>'Locally Advanced Unresectable Basal Cell Carcinoma' EquivalentTo 'Locally Advanced Unresectable Carcinoma' and 'Locally Advanced Basal Cell Carcinoma' and 'Metastatic Unresectable Basal Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156788</classIRI>
<classLabel>Metastatic Unresectable Basal Cell Carcinoma</classLabel>
<newAxiom>'Metastatic Unresectable Basal Cell Carcinoma' EquivalentTo 'Metastatic Unresectable Carcinoma' and 'Metastatic Basal Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156787</classIRI>
<classLabel>Bone Age</classLabel>
<newAxiom>'Bone Age' SubClassOf 'Other Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156786</classIRI>
<classLabel>Skeletally Immature</classLabel>
<newAxiom>'Skeletally Immature' SubClassOf 'Anatomy Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156785</classIRI>
<classLabel>Skeletally Mature</classLabel>
<newAxiom>'Skeletally Mature' SubClassOf 'Anatomy Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156784</classIRI>
<classLabel>Mature</classLabel>
<newAxiom>'Mature' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156783</classIRI>
<classLabel>Laryngeal Mask Airway</classLabel>
<newAxiom>'Laryngeal Mask Airway' SubClassOf 'Medical Device'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156793</classIRI>
<classLabel>Metastatic Human Papillomavirus-Related Malignant Neoplasm</classLabel>
<newAxiom>'Metastatic Human Papillomavirus-Related Malignant Neoplasm' EquivalentTo 'Human Papillomavirus-Related Malignant Neoplasm' and 'Metastatic Malignant Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156792</classIRI>
<classLabel>GSK-3 Inhibitor 9-ING-41</classLabel>
<newAxiom>'GSK-3 Inhibitor 9-ING-41' SubClassOf 'Protein Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156791</classIRI>
<classLabel>Anti-PVRIG Monoclonal Antibody COM701</classLabel>
<newAxiom>'Anti-PVRIG Monoclonal Antibody COM701' SubClassOf 'Immune Checkpoint Modulator'</newAxiom>
<newAxiom>'Anti-PVRIG Monoclonal Antibody COM701' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156790</classIRI>
<classLabel>Maternally Derived Graft Versus Host Disease</classLabel>
<newAxiom>'Maternally Derived Graft Versus Host Disease' SubClassOf 'Graft Versus Host Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156799</classIRI>
<classLabel>PVRIG wt Allele</classLabel>
<newAxiom>'PVRIG wt Allele' SubClassOf 'PVRIG Gene'</newAxiom>
<newAxiom>'PVRIG wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '7q22.1'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156798</classIRI>
<classLabel>PVRIG Gene</classLabel>
<newAxiom>'PVRIG Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Negative Regulation of Lymphocyte Activation'</newAxiom>
<newAxiom>'PVRIG Gene' SubClassOf 'Receptor Gene'</newAxiom>
<newAxiom>'PVRIG Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immunosuppressive Effect'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156797</classIRI>
<classLabel>Prior Systemic Therapy for Current Cancer</classLabel>
<newAxiom>'Prior Systemic Therapy for Current Cancer' SubClassOf 'Prior Treatment of Current Cancer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156796</classIRI>
<classLabel>Prior Systemic Chemotherapy for Current Cancer</classLabel>
<newAxiom>'Prior Systemic Chemotherapy for Current Cancer' SubClassOf 'Prior Systemic Therapy for Current Cancer'</newAxiom>
<newAxiom>'Prior Systemic Chemotherapy for Current Cancer' SubClassOf 'Prior Chemotherapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156795</classIRI>
<classLabel>Prior Radiation Therapy of Affected Breast</classLabel>
<newAxiom>'Prior Radiation Therapy of Affected Breast' SubClassOf 'Prior Radiation Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156794</classIRI>
<classLabel>ITK Inhibitor</classLabel>
<newAxiom>'ITK Inhibitor' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'ITK Inhibitor' SubClassOf 'Tyrosine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156889</classIRI>
<classLabel>Anti-K-RAS G12D mTCR-transduced Autologous Peripheral Blood Lymphocytes</classLabel>
<newAxiom>'Anti-K-RAS G12D mTCR-transduced Autologous Peripheral Blood Lymphocytes' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Anti-K-RAS G12D mTCR-transduced Autologous Peripheral Blood Lymphocytes' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Anti-K-RAS G12D mTCR-transduced Autologous Peripheral Blood Lymphocytes' SubClassOf 'T-cell Receptor-engineered T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156888</classIRI>
<classLabel>HRAS NP_005334.1:p.G12D</classLabel>
<newAxiom>'HRAS NP_005334.1:p.G12D' SubClassOf ('Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'HRAS NM_005343.3:c.35GA') or ('Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'HRAS NM_005343.3:c.35_36delGCinsAT')</newAxiom>
<newAxiom>'HRAS NP_005334.1:p.G12D' SubClassOf 'HRAS NP_005334.1:p.G12X'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156887</classIRI>
<classLabel>HRAS NM_005343.3:c.35_36delGCinsAT</classLabel>
<newAxiom>'HRAS NM_005343.3:c.35_36delGCinsAT' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'HRAS NP_005334.1:p.G12D'</newAxiom>
<newAxiom>'HRAS NM_005343.3:c.35_36delGCinsAT' SubClassOf 'HRAS Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156886</classIRI>
<classLabel>HRAS NM_005343.3:c.35GA</classLabel>
<newAxiom>'HRAS NM_005343.3:c.35GA' SubClassOf 'HRAS Gene Mutation'</newAxiom>
<newAxiom>'HRAS NM_005343.3:c.35GA' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'HRAS NP_005334.1:p.G12D'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156885</classIRI>
<classLabel>Malignant Bronchial Neoplasm</classLabel>
<newAxiom>'Malignant Bronchial Neoplasm' EquivalentTo 'Malignant Respiratory Tract Neoplasm' and ('Disease_Has_Associated_Anatomic_Site' some 'Bronchus')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156884</classIRI>
<classLabel>HRAS NP_005334.1:p.G12X</classLabel>
<newAxiom>'HRAS NP_005334.1:p.G12X' SubClassOf 'HRAS Protein Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156883</classIRI>
<classLabel>Autologous CD4+/CD8+ EGFR806 Specific 4-1BB-CD3zeta-EGFRt-expressing CAR T Cells</classLabel>
<newAxiom>'Autologous CD4+/CD8+ EGFR806 Specific 4-1BB-CD3zeta-EGFRt-expressing CAR T Cells' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous CD4+/CD8+ EGFR806 Specific 4-1BB-CD3zeta-EGFRt-expressing CAR T Cells' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous CD4+/CD8+ EGFR806 Specific 4-1BB-CD3zeta-EGFRt-expressing CAR T Cells' SubClassOf 'T-cell Receptor-engineered T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156882</classIRI>
<classLabel>Anti-CD22 ADC TRPH-222</classLabel>
<newAxiom>'Anti-CD22 ADC TRPH-222' SubClassOf 'Anti-CD22 Antibody-drug Conjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156892</classIRI>
<classLabel>HER2/Neu Status by Validated Dual-probe in Situ Hybridization</classLabel>
<newAxiom>'HER2/Neu Status by Validated Dual-probe in Situ Hybridization' SubClassOf 'In Situ Hybridization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156891</classIRI>
<classLabel>HER2/Neu Status by Validated Single-probe in Situ Hybridization</classLabel>
<newAxiom>'HER2/Neu Status by Validated Single-probe in Situ Hybridization' SubClassOf 'In Situ Hybridization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156890</classIRI>
<classLabel>HER2/Neu Expression by Validated Immunohistochemistry</classLabel>
<newAxiom>'HER2/Neu Expression by Validated Immunohistochemistry' SubClassOf 'Immunohistochemical Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156899</classIRI>
<classLabel>Hemoglobin S/O-Arab Heterozygote</classLabel>
<newAxiom>'Hemoglobin S/O-Arab Heterozygote' SubClassOf 'Abnormal Blood Chemistry and Hematology Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156898</classIRI>
<classLabel>Exercise Log</classLabel>
<newAxiom>'Exercise Log' SubClassOf 'Log'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156897</classIRI>
<classLabel>Activity Monitor</classLabel>
<newAxiom>'Activity Monitor' SubClassOf 'Diagnostic, Therapeutic, or Research Equipment'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156896</classIRI>
<classLabel>APPSPIRE</classLabel>
<newAxiom>'APPSPIRE' SubClassOf 'Smartphone Application'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156895</classIRI>
<classLabel>Larotrectinib Sulfate</classLabel>
<newAxiom>'Larotrectinib Sulfate' SubClassOf 'Tyrosine Kinase Inhibitor'</newAxiom>
<newAxiom>'Larotrectinib Sulfate' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156894</classIRI>
<classLabel>Glasdegib Maleate</classLabel>
<newAxiom>'Glasdegib Maleate' SubClassOf 'Smoothened Antagonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156893</classIRI>
<classLabel>PD-1 Ligand Inhibitor</classLabel>
<newAxiom>'PD-1 Ligand Inhibitor' SubClassOf 'Immune Checkpoint Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156867</classIRI>
<classLabel>Flour, Feed, or Grain Milling</classLabel>
<newAxiom>'Flour, Feed, or Grain Milling' SubClassOf 'Manufacturer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156866</classIRI>
<classLabel>Hard Rock Mining</classLabel>
<newAxiom>'Hard Rock Mining' SubClassOf 'Construction and Extraction Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156865</classIRI>
<classLabel>Coal Mining</classLabel>
<newAxiom>'Coal Mining' SubClassOf 'Construction and Extraction Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156864</classIRI>
<classLabel>Steel Milling and Casting</classLabel>
<newAxiom>'Steel Milling and Casting' SubClassOf 'Metal Workers and Plastic Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156863</classIRI>
<classLabel>Aluminum Milling</classLabel>
<newAxiom>'Aluminum Milling' SubClassOf 'Metal Workers and Plastic Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156862</classIRI>
<classLabel>Fractionated Stereotactic Radiation Therapy</classLabel>
<newAxiom>'Fractionated Stereotactic Radiation Therapy' SubClassOf 'Stereotactic Radiosurgery'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156861</classIRI>
<classLabel>Human Papillomavirus mRNA</classLabel>
<newAxiom>'Human Papillomavirus mRNA' SubClassOf 'Messenger RNA'</newAxiom>
<newAxiom>'Human Papillomavirus mRNA' SubClassOf 'Gene_Product_Has_Organism_Source' some 'Human Papillomavirus'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156860</classIRI>
<classLabel>Number of Days from Date of Initial Cancer Diagnosis to Date of Additional Surgery for New Tumor Event</classLabel>
<newAxiom>'Number of Days from Date of Initial Cancer Diagnosis to Date of Additional Surgery for New Tumor Event' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156869</classIRI>
<classLabel>Sand Blasting</classLabel>
<newAxiom>'Sand Blasting' SubClassOf 'Miscellaneous Occupation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156868</classIRI>
<classLabel>Mineral Cutting</classLabel>
<newAxiom>'Mineral Cutting' SubClassOf 'Miscellaneous Occupation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156878</classIRI>
<classLabel>Quit2Heal</classLabel>
<newAxiom>'Quit2Heal' SubClassOf 'Smartphone Application'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156877</classIRI>
<classLabel>Smartphone Application</classLabel>
<newAxiom>'Smartphone Application' SubClassOf 'Computer Application'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156876</classIRI>
<classLabel>Cancer Model Development Center</classLabel>
<newAxiom>'Cancer Model Development Center' SubClassOf 'Professional Organization or Group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156875</classIRI>
<classLabel>Other Investigational Agent</classLabel>
<newAxiom>'Other Investigational Agent' SubClassOf 'Protocol Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156874</classIRI>
<classLabel>Natural Gas</classLabel>
<newAxiom>'Natural Gas' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156873</classIRI>
<classLabel>Creosote</classLabel>
<newAxiom>'Creosote' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156872</classIRI>
<classLabel>Cotton or Jute Dust Exposure</classLabel>
<newAxiom>'Cotton or Jute Dust Exposure' SubClassOf 'Environmental Exposure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156871</classIRI>
<classLabel>Solder Fume Exposure</classLabel>
<newAxiom>'Solder Fume Exposure' SubClassOf 'Environmental Exposure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156879</classIRI>
<classLabel>QuitGuide</classLabel>
<newAxiom>'QuitGuide' SubClassOf 'Smartphone Application'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156880</classIRI>
<classLabel>HSP90 Inhibitor</classLabel>
<newAxiom>'HSP90 Inhibitor' SubClassOf 'Heat Shock Protein Inhibitor'</newAxiom>
<newAxiom>'HSP90 Inhibitor' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Positive Regulation of Apoptosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156845</classIRI>
<classLabel>48 Months</classLabel>
<newAxiom>'48 Months' SubClassOf 'Period'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156844</classIRI>
<classLabel>36 Months</classLabel>
<newAxiom>'36 Months' SubClassOf 'Period'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156843</classIRI>
<classLabel>24 Months</classLabel>
<newAxiom>'24 Months' SubClassOf 'Period'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156842</classIRI>
<classLabel>12 Months</classLabel>
<newAxiom>'12 Months' SubClassOf 'Period'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156841</classIRI>
<classLabel>Follow-up Period</classLabel>
<newAxiom>'Follow-up Period' SubClassOf 'Period'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156840</classIRI>
<classLabel>Organ of Origin</classLabel>
<newAxiom>'Organ of Origin' SubClassOf 'Other Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156849</classIRI>
<classLabel>With Tumor</classLabel>
<newAxiom>'With Tumor' SubClassOf 'Tumor Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156848</classIRI>
<classLabel>Tumor Free</classLabel>
<newAxiom>'Tumor Free' SubClassOf 'Tumor Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156847</classIRI>
<classLabel>Outcome after Follow-up</classLabel>
<newAxiom>'Outcome after Follow-up' SubClassOf 'Follow-up Information'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156846</classIRI>
<classLabel>Follow-up Information</classLabel>
<newAxiom>'Follow-up Information' SubClassOf 'Information'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156856</classIRI>
<classLabel>Number of Days from Date of Initial Cancer Diagnosis to Date of New Tumor Event after Initial Treatment</classLabel>
<newAxiom>'Number of Days from Date of Initial Cancer Diagnosis to Date of New Tumor Event after Initial Treatment' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156855</classIRI>
<classLabel>Date of New Tumor Event</classLabel>
<newAxiom>'Date of New Tumor Event' SubClassOf 'Tumor Event Information'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156854</classIRI>
<classLabel>Specify other Site of New Tumor Event</classLabel>
<newAxiom>'Specify other Site of New Tumor Event' SubClassOf 'Tumor Event Information'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156853</classIRI>
<classLabel>Site of New Tumor Event</classLabel>
<newAxiom>'Site of New Tumor Event' SubClassOf 'Tumor Event Information'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156852</classIRI>
<classLabel>Type of New Tumor Event</classLabel>
<newAxiom>'Type of New Tumor Event' SubClassOf 'Tumor Event Information'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156851</classIRI>
<classLabel>New Tumor Event</classLabel>
<newAxiom>'New Tumor Event' SubClassOf 'Tumor Event Information'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156850</classIRI>
<classLabel>New Tumor Event After Initial Treatment</classLabel>
<newAxiom>'New Tumor Event After Initial Treatment' SubClassOf 'Tumor Event Information'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156859</classIRI>
<classLabel>Date of Additional Surgery for New Tumor Event</classLabel>
<newAxiom>'Date of Additional Surgery for New Tumor Event' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156858</classIRI>
<classLabel>Additional Surgery for New Tumor Event</classLabel>
<newAxiom>'Additional Surgery for New Tumor Event' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156857</classIRI>
<classLabel>Number of Days from Date of Initial Pathologic Diagnosis to Date of Additional Surgery for New Tumor Event</classLabel>
<newAxiom>'Number of Days from Date of Initial Pathologic Diagnosis to Date of Additional Surgery for New Tumor Event' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156823</classIRI>
<classLabel>Alcohol Use History Not Available</classLabel>
<newAxiom>'Alcohol Use History Not Available' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156822</classIRI>
<classLabel>Consumed alcohol in the past, but currently a non-drinker</classLabel>
<newAxiom>'Consumed alcohol in the past, but currently a non-drinker' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156821</classIRI>
<classLabel>Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women</classLabel>
<newAxiom>'Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156820</classIRI>
<classLabel>Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women</classLabel>
<newAxiom>'Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156829</classIRI>
<classLabel>Current Reformed Smoker Within Past 15 Years</classLabel>
<newAxiom>'Current Reformed Smoker Within Past 15 Years' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156828</classIRI>
<classLabel>Current Reformed Smoker, More than 15 Years</classLabel>
<newAxiom>'Current Reformed Smoker, More than 15 Years' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156827</classIRI>
<classLabel>Current Smoker Includes Daily and Non-daily Smokers</classLabel>
<newAxiom>'Current Smoker Includes Daily and Non-daily Smokers' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156826</classIRI>
<classLabel>Lifelong non-smoker Less than 100 cigarettes smoked in lifetime</classLabel>
<newAxiom>'Lifelong non-smoker Less than 100 cigarettes smoked in lifetime' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156825</classIRI>
<classLabel>Smoking History</classLabel>
<newAxiom>'Smoking History' SubClassOf 'Personal Medical History'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156824</classIRI>
<classLabel>Number of years Participant has consumed more than 2 drinks per day for men and more than 1 drink per day for women</classLabel>
<newAxiom>'Number of years Participant has consumed more than 2 drinks per day for men and more than 1 drink per day for women' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156834</classIRI>
<classLabel>Number of Pack Years Smoked</classLabel>
<newAxiom>'Number of Pack Years Smoked' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156833</classIRI>
<classLabel>When Participant Smoked, How many Cigarettes Smoked</classLabel>
<newAxiom>'When Participant Smoked, How many Cigarettes Smoked' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156832</classIRI>
<classLabel>Age Which Participant Stopped Smoking</classLabel>
<newAxiom>'Age Which Participant Stopped Smoking' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156831</classIRI>
<classLabel>Smoking History Not Available</classLabel>
<newAxiom>'Smoking History Not Available' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156830</classIRI>
<classLabel>Current Reformed Smoker, Years Unknown</classLabel>
<newAxiom>'Current Reformed Smoker, Years Unknown' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156839</classIRI>
<classLabel>Secondhand Smoke Exposure History Not Available</classLabel>
<newAxiom>'Secondhand Smoke Exposure History Not Available' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156838</classIRI>
<classLabel>Secondhand Smoke Exposure in Current Household</classLabel>
<newAxiom>'Secondhand Smoke Exposure in Current Household' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156837</classIRI>
<classLabel>Secondhand Smoke Exposure in Household during Childhood</classLabel>
<newAxiom>'Secondhand Smoke Exposure in Household during Childhood' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156836</classIRI>
<classLabel>No/Minimal Secondhand Smoke Exposure</classLabel>
<newAxiom>'No/Minimal Secondhand Smoke Exposure' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156835</classIRI>
<classLabel>Participant Exposed to Secondhand Smoke</classLabel>
<newAxiom>'Participant Exposed to Secondhand Smoke' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156801</classIRI>
<classLabel>Treatment-sensitive HIV Infection</classLabel>
<newAxiom>'Treatment-sensitive HIV Infection' SubClassOf 'HIV Infection'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156800</classIRI>
<classLabel>Prior Treatment of Current Cancer</classLabel>
<newAxiom>'Prior Treatment of Current Cancer' SubClassOf 'Prior Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156809</classIRI>
<classLabel>Medical Condition</classLabel>
<newAxiom>'Medical Condition' SubClassOf 'Condition'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156808</classIRI>
<classLabel>Tissue Source Site Identifier</classLabel>
<newAxiom>'Tissue Source Site Identifier' SubClassOf 'Identifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156807</classIRI>
<classLabel>CPTAC Case Identifier</classLabel>
<newAxiom>'CPTAC Case Identifier' SubClassOf 'Identifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156806</classIRI>
<classLabel>New Primary Tumor</classLabel>
<newAxiom>'New Primary Tumor' SubClassOf 'Primary Lesion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156805</classIRI>
<classLabel>Tumor Event Information</classLabel>
<newAxiom>'Tumor Event Information' SubClassOf 'Information'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156804</classIRI>
<classLabel>EZH2 Inhibitor</classLabel>
<newAxiom>'EZH2 Inhibitor' SubClassOf 'Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156803</classIRI>
<classLabel>Transmembrane Protein PVRIG</classLabel>
<newAxiom>'Transmembrane Protein PVRIG' EquivalentTo 'Receptor' and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Expressed_In_Tissue' some 'Natural Killer Cell') and ('Gene_Product_Expressed_In_Tissue' some 'CD8-Positive T-Lymphocyte') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Cell Surface Receptor') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Negative Regulation of Lymphocyte Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immunosuppressive Effect') and ('Gene_Product_Encoded_By_Gene' some 'PVRIG Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156802</classIRI>
<classLabel>Radiation to Greater than 25 Percent of Bone Marrow</classLabel>
<newAxiom>'Radiation to Greater than 25 Percent of Bone Marrow' SubClassOf 'Bone Marrow Ablation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156812</classIRI>
<classLabel>Medical History Source</classLabel>
<newAxiom>'Medical History Source' SubClassOf 'Source'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156811</classIRI>
<classLabel>Treatment History</classLabel>
<newAxiom>'Treatment History' SubClassOf 'Personal Medical History'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156810</classIRI>
<classLabel>New Tumor Event Information</classLabel>
<newAxiom>'New Tumor Event Information' SubClassOf 'Tumor Event Information'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156819</classIRI>
<classLabel>Date of Last Administration</classLabel>
<newAxiom>'Date of Last Administration' SubClassOf 'Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156818</classIRI>
<classLabel>Current Medication</classLabel>
<newAxiom>'Current Medication' SubClassOf 'Pharmacologic Management'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156817</classIRI>
<classLabel>Medical Record Documentation about this History of Cancer Treatment</classLabel>
<newAxiom>'Medical Record Documentation about this History of Cancer Treatment' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156816</classIRI>
<classLabel>Month-Day-Year</classLabel>
<newAxiom>'Month-Day-Year' SubClassOf 'Month'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156815</classIRI>
<classLabel>Date of Last Chemotherapy Treatment</classLabel>
<newAxiom>'Date of Last Chemotherapy Treatment' SubClassOf 'Date of Therapeutic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156814</classIRI>
<classLabel>Date of Last Radiation Treatment</classLabel>
<newAxiom>'Date of Last Radiation Treatment' SubClassOf 'Date of Therapeutic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156813</classIRI>
<classLabel>Initial Diagnosis</classLabel>
<newAxiom>'Initial Diagnosis' SubClassOf 'Diagnosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156526</classIRI>
<classLabel>Soluble TNF Superfamily Member 12 Measurement</classLabel>
<newAxiom>'Soluble TNF Superfamily Member 12 Measurement' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156525</classIRI>
<classLabel>TNF Superfamily Member 12 Excretion Rate</classLabel>
<newAxiom>'TNF Superfamily Member 12 Excretion Rate' SubClassOf 'Excretion Rate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156524</classIRI>
<classLabel>Pyocytes Measurement</classLabel>
<newAxiom>'Pyocytes Measurement' SubClassOf 'Cell Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156523</classIRI>
<classLabel>Pro-gastrin Releasing Peptide Measurement</classLabel>
<newAxiom>'Pro-gastrin Releasing Peptide Measurement' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156522</classIRI>
<classLabel>Phosphorylated STAT3 to STAT3 Ratio Measurement</classLabel>
<newAxiom>'Phosphorylated STAT3 to STAT3 Ratio Measurement' SubClassOf 'STAT3 Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156521</classIRI>
<classLabel>Phosphorylated STAT3 Measurement</classLabel>
<newAxiom>'Phosphorylated STAT3 Measurement' SubClassOf 'STAT3 Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156520</classIRI>
<classLabel>Chemokine (C-C Motif) Ligand 2 Excretion Rate</classLabel>
<newAxiom>'Chemokine (C-C Motif) Ligand 2 Excretion Rate' SubClassOf 'Excretion Rate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156529</classIRI>
<classLabel>25-Hydroxyvitamin D3 Measurement</classLabel>
<newAxiom>'25-Hydroxyvitamin D3 Measurement' SubClassOf 'Vitamin D3 Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156528</classIRI>
<classLabel>25-Hydroxyvitamin D2 Measurement</classLabel>
<newAxiom>'25-Hydroxyvitamin D2 Measurement' SubClassOf 'Vitamin D2 Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156527</classIRI>
<classLabel>Vascular Endothelial Growth Factor Receptor 2 Measurement</classLabel>
<newAxiom>'Vascular Endothelial Growth Factor Receptor 2 Measurement' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156537</classIRI>
<classLabel>Delta Aminolevulinate Measurement</classLabel>
<newAxiom>'Delta Aminolevulinate Measurement' SubClassOf 'Amino Acid Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156536</classIRI>
<classLabel>Decanoylcarnitine Measurement</classLabel>
<newAxiom>'Decanoylcarnitine Measurement' SubClassOf 'Lipid Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156535</classIRI>
<classLabel>Acylcarnitine Measurement</classLabel>
<newAxiom>'Acylcarnitine Measurement' SubClassOf 'Amino Acid Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156534</classIRI>
<classLabel>Acylglycine Measurement</classLabel>
<newAxiom>'Acylglycine Measurement' SubClassOf 'Amino Acid Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156533</classIRI>
<classLabel>Drug Crystal Measurement</classLabel>
<newAxiom>'Drug Crystal Measurement' SubClassOf 'Crystal Growth Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156532</classIRI>
<classLabel>Pyruvate Kinase Isozyme M1 Measurement</classLabel>
<newAxiom>'Pyruvate Kinase Isozyme M1 Measurement' SubClassOf 'Pyruvate Kinase Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156531</classIRI>
<classLabel>Pyruvate Kinase Isozyme M2 Measurement</classLabel>
<newAxiom>'Pyruvate Kinase Isozyme M2 Measurement' SubClassOf 'Pyruvate Kinase Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156530</classIRI>
<classLabel>Pyruvate Kinase Muscle Isozyme Measurement</classLabel>
<newAxiom>'Pyruvate Kinase Muscle Isozyme Measurement' SubClassOf 'Pyruvate Kinase Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156539</classIRI>
<classLabel>Porphobilinogen Measurement</classLabel>
<newAxiom>'Porphobilinogen Measurement' SubClassOf 'Urine Protein Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156538</classIRI>
<classLabel>Delta Aminolevulinate to Creatinine Ratio Measurement</classLabel>
<newAxiom>'Delta Aminolevulinate to Creatinine Ratio Measurement' SubClassOf 'Urine Protein Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156540</classIRI>
<classLabel>Porphobilinogen to Creatinine Ratio Measurement</classLabel>
<newAxiom>'Porphobilinogen to Creatinine Ratio Measurement' SubClassOf 'Urine Protein Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156504</classIRI>
<classLabel>Bowel Perforation Indicator</classLabel>
<newAxiom>'Bowel Perforation Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156503</classIRI>
<classLabel>Bowel Obstruction Indicator</classLabel>
<newAxiom>'Bowel Obstruction Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156502</classIRI>
<classLabel>Thrice</classLabel>
<newAxiom>'Thrice' SubClassOf 'Schedule Frequency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156501</classIRI>
<classLabel>STEAM Pulse Sequence Mixing Time</classLabel>
<newAxiom>'STEAM Pulse Sequence Mixing Time' SubClassOf 'Elapsed Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156500</classIRI>
<classLabel>Voxel Orientation</classLabel>
<newAxiom>'Voxel Orientation' SubClassOf 'Spatial Orientation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156509</classIRI>
<classLabel>Nuclear Matrix Protein 22 Measurement</classLabel>
<newAxiom>'Nuclear Matrix Protein 22 Measurement' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156508</classIRI>
<classLabel>Monoclonal Protein Spike to Total Protein Ratio Measurement</classLabel>
<newAxiom>'Monoclonal Protein Spike to Total Protein Ratio Measurement' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156507</classIRI>
<classLabel>Subarachnoid Space</classLabel>
<newAxiom>'Subarachnoid Space' SubClassOf 'Central Nervous System Part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156506</classIRI>
<classLabel>Tibiotarsal Joint</classLabel>
<newAxiom>'Tibiotarsal Joint' SubClassOf 'Joint by Site'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156505</classIRI>
<classLabel>Lymphovascular Invasion Indicator</classLabel>
<newAxiom>'Lymphovascular Invasion Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156515</classIRI>
<classLabel>Hemoglobin Cast Measurement</classLabel>
<newAxiom>'Hemoglobin Cast Measurement' SubClassOf 'Urine Sediment Analysis Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156514</classIRI>
<classLabel>4-Beta-Hydroxycholesterol Measurement</classLabel>
<newAxiom>'4-Beta-Hydroxycholesterol Measurement' SubClassOf 'Cholesterol Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156513</classIRI>
<classLabel>HDL Phospholipid Measurement</classLabel>
<newAxiom>'HDL Phospholipid Measurement' SubClassOf 'Phospholipid Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156512</classIRI>
<classLabel>Aspartate Aminotransferase to Platelet Ratio Index</classLabel>
<newAxiom>'Aspartate Aminotransferase to Platelet Ratio Index' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156511</classIRI>
<classLabel>24,25-Dihydroxyvitamin D Measurement</classLabel>
<newAxiom>'24,25-Dihydroxyvitamin D Measurement' SubClassOf 'Vitamin D Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156510</classIRI>
<classLabel>Cocaethylene Measurement</classLabel>
<newAxiom>'Cocaethylene Measurement' SubClassOf 'CNS Stimulant Drug Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156519</classIRI>
<classLabel>Interleukin 18 Excretion Rate</classLabel>
<newAxiom>'Interleukin 18 Excretion Rate' SubClassOf 'Excretion Rate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156518</classIRI>
<classLabel>Interleukin 1 Excretion Rate</classLabel>
<newAxiom>'Interleukin 1 Excretion Rate' SubClassOf 'Excretion Rate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156517</classIRI>
<classLabel>Free Immunoglobulin Light Chain Measurement</classLabel>
<newAxiom>'Free Immunoglobulin Light Chain Measurement' SubClassOf 'Immunoglobulin Light Chain Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156516</classIRI>
<classLabel>Fatty Liver Index</classLabel>
<newAxiom>'Fatty Liver Index' SubClassOf 'Liver Function Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156589</classIRI>
<classLabel>Live Birth Indicator</classLabel>
<newAxiom>'Live Birth Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156588</classIRI>
<classLabel>Induced Abortion Indicator</classLabel>
<newAxiom>'Induced Abortion Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156587</classIRI>
<classLabel>Menstrual Cycle Regularity</classLabel>
<newAxiom>'Menstrual Cycle Regularity' SubClassOf 'Female Reproductive System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156586</classIRI>
<classLabel>Menses Duration</classLabel>
<newAxiom>'Menses Duration' SubClassOf 'Female Reproductive System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156585</classIRI>
<classLabel>Menses Flow Rate Description</classLabel>
<newAxiom>'Menses Flow Rate Description' SubClassOf 'Female Reproductive System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156595</classIRI>
<classLabel>Induction Clinical Trial Setting</classLabel>
<newAxiom>'Induction Clinical Trial Setting' SubClassOf 'Treatment Setting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156594</classIRI>
<classLabel>Further Enlargement from Nadir</classLabel>
<newAxiom>'Further Enlargement from Nadir' SubClassOf 'Further Enlargement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156593</classIRI>
<classLabel>Enlargement from Nadir</classLabel>
<newAxiom>'Enlargement from Nadir' SubClassOf 'Enlargement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156592</classIRI>
<classLabel>Open Label for Treatment And Double Blind to Dose</classLabel>
<newAxiom>'Open Label for Treatment And Double Blind to Dose' SubClassOf 'Trial Blinding Schema'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156591</classIRI>
<classLabel>Bone Marrow Mononuclear Cell</classLabel>
<newAxiom>'Bone Marrow Mononuclear Cell' SubClassOf 'Bone Marrow-Derived Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156590</classIRI>
<classLabel>Intramandibular Route of Administration</classLabel>
<newAxiom>'Intramandibular Route of Administration' SubClassOf 'Route of Administration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156599</classIRI>
<classLabel>Consolidation Clinical Trial Setting</classLabel>
<newAxiom>'Consolidation Clinical Trial Setting' SubClassOf 'Treatment Setting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156598</classIRI>
<classLabel>Maintenance Clinical Trial Setting</classLabel>
<newAxiom>'Maintenance Clinical Trial Setting' SubClassOf 'Treatment Setting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156597</classIRI>
<classLabel>Conditioning Clinical Trial Setting</classLabel>
<newAxiom>'Conditioning Clinical Trial Setting' SubClassOf 'Treatment Setting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156596</classIRI>
<classLabel>Mobilization Clinical Trial Setting</classLabel>
<newAxiom>'Mobilization Clinical Trial Setting' SubClassOf 'Treatment Setting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156569</classIRI>
<classLabel>Metabolite Ratio for Maximum Concentration</classLabel>
<newAxiom>'Metabolite Ratio for Maximum Concentration' SubClassOf 'Cmax'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156568</classIRI>
<classLabel>Metabolite Ratio for AUC Dosing Interval</classLabel>
<newAxiom>'Metabolite Ratio for AUC Dosing Interval' SubClassOf 'Area Under the Curve Over Dosing Interval'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156567</classIRI>
<classLabel>Metabolite Ratio AUC Last Nonzero Concentration</classLabel>
<newAxiom>'Metabolite Ratio AUC Last Nonzero Concentration' SubClassOf 'Area Under the Curve From Dosing to Last Concentration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156566</classIRI>
<classLabel>Metabolite Ratio for AUC Infinity Predicted</classLabel>
<newAxiom>'Metabolite Ratio for AUC Infinity Predicted' SubClassOf 'Predicted Area Under the Curve Infinity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156565</classIRI>
<classLabel>Metabolite Ratio for AUC Infinity Observed</classLabel>
<newAxiom>'Metabolite Ratio for AUC Infinity Observed' SubClassOf 'Observed Area Under the Curve Infinity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156564</classIRI>
<classLabel>Anatomic Response</classLabel>
<newAxiom>'Anatomic Response' SubClassOf 'Disease Response'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156563</classIRI>
<classLabel>Glutamate and Glutamine Measurement</classLabel>
<newAxiom>'Glutamate and Glutamine Measurement' SubClassOf 'Amino Acid Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156573</classIRI>
<classLabel>Volume of Distribution Steady State Predicted by Unbound Drug</classLabel>
<newAxiom>'Volume of Distribution Steady State Predicted by Unbound Drug' SubClassOf 'Predicted Steady State Volume of Distribution'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156572</classIRI>
<classLabel>Volume of Distribution Steady State Observed by Unbound Drug</classLabel>
<newAxiom>'Volume of Distribution Steady State Observed by Unbound Drug' SubClassOf 'Area Under the First Moment Curve Over Dosing Interval'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156571</classIRI>
<classLabel>Volume of Distribution Steady State Predicted by Fraction of Dose Absorbed</classLabel>
<newAxiom>'Volume of Distribution Steady State Predicted by Fraction of Dose Absorbed' SubClassOf 'Predicted Steady State Volume of Distribution'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156570</classIRI>
<classLabel>Volume of Distribution Steady State Observed by Fraction of Dose Absorbed</classLabel>
<newAxiom>'Volume of Distribution Steady State Observed by Fraction of Dose Absorbed' SubClassOf 'Area Under the First Moment Curve Over Dosing Interval'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156579</classIRI>
<classLabel>Cmax to Cmax Ratio Measurement</classLabel>
<newAxiom>'Cmax to Cmax Ratio Measurement' SubClassOf 'Cmax'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156578</classIRI>
<classLabel>Area Under the Curve Ratio Infinity Observed</classLabel>
<newAxiom>'Area Under the Curve Ratio Infinity Observed' SubClassOf 'Area Under the Curve Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156577</classIRI>
<classLabel>Area Under the Curve Ratio Infinity Predicted</classLabel>
<newAxiom>'Area Under the Curve Ratio Infinity Predicted' SubClassOf 'Area Under the Curve Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156576</classIRI>
<classLabel>Fractional Excretion from T1 to T2</classLabel>
<newAxiom>'Fractional Excretion from T1 to T2' SubClassOf 'Excretion Rate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156575</classIRI>
<classLabel>Volume of Distribution Steady State Predicted by Bound Drug</classLabel>
<newAxiom>'Volume of Distribution Steady State Predicted by Bound Drug' SubClassOf 'Predicted Steady State Volume of Distribution'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156574</classIRI>
<classLabel>Volume of Distribution Steady State Observed by Bound Drug</classLabel>
<newAxiom>'Volume of Distribution Steady State Observed by Bound Drug' SubClassOf 'Area Under the First Moment Curve Over Dosing Interval'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156584</classIRI>
<classLabel>Alveolar Volume</classLabel>
<newAxiom>'Alveolar Volume' SubClassOf 'Pulmonary Function Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156583</classIRI>
<classLabel>Southern African Coloured</classLabel>
<newAxiom>'Southern African Coloured' SubClassOf 'Multiracial'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156582</classIRI>
<classLabel>Local Immunotherapy Procedure</classLabel>
<newAxiom>'Local Immunotherapy Procedure' SubClassOf 'Immunotherapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156581</classIRI>
<classLabel>Observed Volume of Distribution of Absorbed Fraction for Unbound Drug</classLabel>
<newAxiom>'Observed Volume of Distribution of Absorbed Fraction for Unbound Drug' SubClassOf 'Observed Volume of Distribution of Absorbed Fraction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156580</classIRI>
<classLabel>Cmax to Cmin Ratio Measurement</classLabel>
<newAxiom>'Cmax to Cmin Ratio Measurement' SubClassOf 'Pharmaceutical Product Characteristics'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156548</classIRI>
<classLabel>Positive Cell Count</classLabel>
<newAxiom>'Positive Cell Count' SubClassOf 'Cell Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156547</classIRI>
<classLabel>Intact Epithelial Reticular Basement Membrane Length to Total Epithelial Reticular Basement Membrane Length Ratio Measurement</classLabel>
<newAxiom>'Intact Epithelial Reticular Basement Membrane Length to Total Epithelial Reticular Basement Membrane Length Ratio Measurement' SubClassOf 'Basement Membrane Coverage Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156546</classIRI>
<classLabel>Beta-defensin 1 Measurement</classLabel>
<newAxiom>'Beta-defensin 1 Measurement' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156545</classIRI>
<classLabel>Blood Vessel Density</classLabel>
<newAxiom>'Blood Vessel Density' SubClassOf 'Histopathologic Examination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156544</classIRI>
<classLabel>CD68 Expressing Cell Count</classLabel>
<newAxiom>'CD68 Expressing Cell Count' SubClassOf 'Cell Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156543</classIRI>
<classLabel>Mycoplasma pneumoniae Measurement</classLabel>
<newAxiom>'Mycoplasma pneumoniae Measurement' SubClassOf 'Microbiology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156542</classIRI>
<classLabel>Human Parvovirus B19 Measurement</classLabel>
<newAxiom>'Human Parvovirus B19 Measurement' SubClassOf 'Microbiology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156541</classIRI>
<classLabel>Separated</classLabel>
<newAxiom>'Separated' SubClassOf 'Marital Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156549</classIRI>
<classLabel>Injection Needle Reuse</classLabel>
<newAxiom>'Injection Needle Reuse' SubClassOf 'Reuse of Single Use Device'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156551</classIRI>
<classLabel>No Longer Clinically Benefiting</classLabel>
<newAxiom>'No Longer Clinically Benefiting' SubClassOf 'Treatment Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156550</classIRI>
<classLabel>Susceptibility Score Mutations Indicator</classLabel>
<newAxiom>'Susceptibility Score Mutations Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156559</classIRI>
<classLabel>Peak Response Amplitude</classLabel>
<newAxiom>'Peak Response Amplitude' SubClassOf 'Amplitude'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156558</classIRI>
<classLabel>REM to Total Sleep Time Ratio Measurement</classLabel>
<newAxiom>'REM to Total Sleep Time Ratio Measurement' SubClassOf 'Sleep Study'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156557</classIRI>
<classLabel>N3 Sleep to Total Sleep Time Ratio Measurement</classLabel>
<newAxiom>'N3 Sleep to Total Sleep Time Ratio Measurement' SubClassOf 'Sleep Study'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156556</classIRI>
<classLabel>N2 Sleep to Total Sleep Time Ratio Measurement</classLabel>
<newAxiom>'N2 Sleep to Total Sleep Time Ratio Measurement' SubClassOf 'Sleep Study'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156555</classIRI>
<classLabel>N1 Sleep to Total Sleep Time Ratio Measurement</classLabel>
<newAxiom>'N1 Sleep to Total Sleep Time Ratio Measurement' SubClassOf 'Sleep Study'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156554</classIRI>
<classLabel>Wake After Sleep Onset</classLabel>
<newAxiom>'Wake After Sleep Onset' SubClassOf 'Sleep Study'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156553</classIRI>
<classLabel>Sleep Efficiency</classLabel>
<newAxiom>'Sleep Efficiency' SubClassOf 'Sleep Study'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156552</classIRI>
<classLabel>Total Sleep Time</classLabel>
<newAxiom>'Total Sleep Time' SubClassOf 'Sleep Study'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156562</classIRI>
<classLabel>Myo-Inositol Measurement</classLabel>
<newAxiom>'Myo-Inositol Measurement' SubClassOf 'Chemistry Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156561</classIRI>
<classLabel>N-Acetyl Aspartate Measurement</classLabel>
<newAxiom>'N-Acetyl Aspartate Measurement' SubClassOf 'Amino Acid Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156560</classIRI>
<classLabel>Peak Response Amplitude Latency</classLabel>
<newAxiom>'Peak Response Amplitude Latency' SubClassOf 'Elapsed Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156647</classIRI>
<classLabel>Consolidated Health Informatics</classLabel>
<newAxiom>'Consolidated Health Informatics' SubClassOf 'Research Activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156646</classIRI>
<classLabel>American Health Information Community</classLabel>
<newAxiom>'American Health Information Community' SubClassOf 'Professional Organization or Group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156645</classIRI>
<classLabel>ADROIT Electronically Generated Information Service</classLabel>
<newAxiom>'ADROIT Electronically Generated Information Service' SubClassOf 'Software Service'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156644</classIRI>
<classLabel>Biosimilar</classLabel>
<newAxiom>'Biosimilar' SubClassOf 'Biological Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156643</classIRI>
<classLabel>Medicinal Product Classification</classLabel>
<newAxiom>'Medicinal Product Classification' SubClassOf 'Classification'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156642</classIRI>
<classLabel>Marketing Authorization</classLabel>
<newAxiom>'Marketing Authorization' SubClassOf 'Authorization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156641</classIRI>
<classLabel>Reference Member State</classLabel>
<newAxiom>'Reference Member State' SubClassOf 'State'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156640</classIRI>
<classLabel>Concerned Member State</classLabel>
<newAxiom>'Concerned Member State' SubClassOf 'State'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156649</classIRI>
<classLabel>Electronic Document Room</classLabel>
<newAxiom>'Electronic Document Room' SubClassOf 'Digital Data Repository'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156648</classIRI>
<classLabel>Development International Birth Date</classLabel>
<newAxiom>'Development International Birth Date' SubClassOf 'Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156650</classIRI>
<classLabel>Health Information Exchange</classLabel>
<newAxiom>'Health Information Exchange' SubClassOf 'Healthcare Activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156658</classIRI>
<classLabel>Regional Health Information Organization</classLabel>
<newAxiom>'Regional Health Information Organization' SubClassOf 'Retired Concept Current Year'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156657</classIRI>
<classLabel>No Observable Effect Level</classLabel>
<newAxiom>'No Observable Effect Level' SubClassOf 'Retired Concept Current Year'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156656</classIRI>
<classLabel>Health Information Exchange</classLabel>
<newAxiom>'Health Information Exchange' SubClassOf 'Retired Concept Current Year'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156655</classIRI>
<classLabel>Electronic Document Room</classLabel>
<newAxiom>'Electronic Document Room' SubClassOf 'Retired Concept Current Year'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156654</classIRI>
<classLabel>Development International Birth Date</classLabel>
<newAxiom>'Development International Birth Date' SubClassOf 'Retired Concept Current Year'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156653</classIRI>
<classLabel>Standard for the Exchange of Nonclinical Data</classLabel>
<newAxiom>'Standard for the Exchange of Nonclinical Data' SubClassOf 'CDISC Standard'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156652</classIRI>
<classLabel>Regional Health Information Organization</classLabel>
<newAxiom>'Regional Health Information Organization' SubClassOf 'Professional Organization or Group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156651</classIRI>
<classLabel>No Observable Effect Level</classLabel>
<newAxiom>'No Observable Effect Level' SubClassOf 'Quantity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156659</classIRI>
<classLabel>Standard for the Exchange of Nonclinical Data</classLabel>
<newAxiom>'Standard for the Exchange of Nonclinical Data' SubClassOf 'Retired Concept Current Year'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156661</classIRI>
<classLabel>Water Signal Suppression Method</classLabel>
<newAxiom>'Water Signal Suppression Method' SubClassOf 'Medical Device Attribute'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156660</classIRI>
<classLabel>Genitourinary System Disorder</classLabel>
<newAxiom>'Genitourinary System Disorder' SubClassOf 'Disorder by Site'</newAxiom>
<newAxiom>'Genitourinary System Disorder' SubClassOf 'Disease_Has_Associated_Anatomic_Site' some 'Genitourinary System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156625</classIRI>
<classLabel>Device Manufacture</classLabel>
<newAxiom>'Device Manufacture' SubClassOf 'Manufacturer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156624</classIRI>
<classLabel>Extent of Exposure</classLabel>
<newAxiom>'Extent of Exposure' SubClassOf 'Extent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156623</classIRI>
<classLabel>Individual Exposure</classLabel>
<newAxiom>'Individual Exposure' SubClassOf 'Exposure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156622</classIRI>
<classLabel>Attributable, Legible, Contemporaneous, Original, Accurate Plus</classLabel>
<newAxiom>'Attributable, Legible, Contemporaneous, Original, Accurate Plus' SubClassOf 'Guideline'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156621</classIRI>
<classLabel>Attributable, Legible, Contemporaneous, Original, Accurate</classLabel>
<newAxiom>'Attributable, Legible, Contemporaneous, Original, Accurate' SubClassOf 'Guideline'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156620</classIRI>
<classLabel>Clinical Trial Results Registry</classLabel>
<newAxiom>'Clinical Trial Results Registry' SubClassOf 'Clinical Trial Registry'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156629</classIRI>
<classLabel>Anticipated Adverse Event</classLabel>
<newAxiom>'Anticipated Adverse Event' SubClassOf 'Adverse Event'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156628</classIRI>
<classLabel>Device Use Error</classLabel>
<newAxiom>'Device Use Error' SubClassOf 'Error'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156627</classIRI>
<classLabel>Medication Error</classLabel>
<newAxiom>'Medication Error' SubClassOf 'Error'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156626</classIRI>
<classLabel>Drug Manufacturer</classLabel>
<newAxiom>'Drug Manufacturer' SubClassOf 'Manufacturer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156636</classIRI>
<classLabel>Serious Breach</classLabel>
<newAxiom>'Serious Breach' SubClassOf 'Protocol Deviation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156635</classIRI>
<classLabel>Mutual Recognition Procedure</classLabel>
<newAxiom>'Mutual Recognition Procedure' SubClassOf 'Marketing Authorization Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156634</classIRI>
<classLabel>Clinical Outcome Assessment Criterion Validation</classLabel>
<newAxiom>'Clinical Outcome Assessment Criterion Validation' SubClassOf 'Criterion Validity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156633</classIRI>
<classLabel>Clinical Outcome Assessment Construct Validation</classLabel>
<newAxiom>'Clinical Outcome Assessment Construct Validation' SubClassOf 'Construct Validity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156632</classIRI>
<classLabel>Clinical Outcome Assessment Content Validation</classLabel>
<newAxiom>'Clinical Outcome Assessment Content Validation' SubClassOf 'Content Validity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156631</classIRI>
<classLabel>Clinical Trial Suspension</classLabel>
<newAxiom>'Clinical Trial Suspension' SubClassOf 'Clinical Study Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156630</classIRI>
<classLabel>Clinical Trial Temporary Halt</classLabel>
<newAxiom>'Clinical Trial Temporary Halt' SubClassOf 'Clinical Study Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156639</classIRI>
<classLabel>Subject Monitoring</classLabel>
<newAxiom>'Subject Monitoring' SubClassOf 'Study Activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156638</classIRI>
<classLabel>Accelerated Approval</classLabel>
<newAxiom>'Accelerated Approval' SubClassOf 'Approval'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156637</classIRI>
<classLabel>Privacy Breach</classLabel>
<newAxiom>'Privacy Breach' SubClassOf 'Disclosure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156603</classIRI>
<classLabel>FDA Technical Specification Name and Version</classLabel>
<newAxiom>'FDA Technical Specification Name and Version' SubClassOf 'Name and Version'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156602</classIRI>
<classLabel>CDISC Therapeutic Area User Guide Name and Version</classLabel>
<newAxiom>'CDISC Therapeutic Area User Guide Name and Version' SubClassOf 'Name and Version'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156601</classIRI>
<classLabel>Additional Outcome Measure</classLabel>
<newAxiom>'Additional Outcome Measure' SubClassOf 'Component of Study Protocol'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156600</classIRI>
<classLabel>Salvage Clinical Trial Setting</classLabel>
<newAxiom>'Salvage Clinical Trial Setting' SubClassOf 'Treatment Setting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156609</classIRI>
<classLabel>Experimental Organism Ductal Cell Adenocarcinoma</classLabel>
<newAxiom>'Experimental Organism Ductal Cell Adenocarcinoma' SubClassOf 'Experimental Organism Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156608</classIRI>
<classLabel>Experimental Organism Intramural Schwannoma</classLabel>
<newAxiom>'Experimental Organism Intramural Schwannoma' SubClassOf 'Experimental Organism Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156607</classIRI>
<classLabel>Experimental Organism Endocardial Schwannoma</classLabel>
<newAxiom>'Experimental Organism Endocardial Schwannoma' SubClassOf 'Experimental Organism Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156606</classIRI>
<classLabel>Chest Circumference</classLabel>
<newAxiom>'Chest Circumference' SubClassOf 'Circumference'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156605</classIRI>
<classLabel>Study Data Tabulation Model Version</classLabel>
<newAxiom>'Study Data Tabulation Model Version' SubClassOf 'Version'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156604</classIRI>
<classLabel>Study Data Tabulation Model Implementation Guide Version</classLabel>
<newAxiom>'Study Data Tabulation Model Implementation Guide Version' SubClassOf 'Version'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156614</classIRI>
<classLabel>Irreversible Inhibitor</classLabel>
<newAxiom>'Irreversible Inhibitor' SubClassOf 'Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156613</classIRI>
<classLabel>Experimental Organism Malignant Thecoma</classLabel>
<newAxiom>'Experimental Organism Malignant Thecoma' SubClassOf 'Experimental Organism Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156612</classIRI>
<classLabel>Experimental Organism Benign Thecoma</classLabel>
<newAxiom>'Experimental Organism Benign Thecoma' SubClassOf 'Experimental Organism Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156611</classIRI>
<classLabel>Experimental Organism Brunner's Gland Carcinoma</classLabel>
<newAxiom>'Experimental Organism Brunner's Gland Carcinoma' SubClassOf 'Experimental Organism Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156610</classIRI>
<classLabel>Experimental Organism Ductal Cell Adenoma</classLabel>
<newAxiom>'Experimental Organism Ductal Cell Adenoma' SubClassOf 'Experimental Organism Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156618</classIRI>
<classLabel>Authorized Auxiliary Medicinal Product</classLabel>
<newAxiom>'Authorized Auxiliary Medicinal Product' SubClassOf 'Auxiliary Medicinal Product'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156617</classIRI>
<classLabel>Authorized Investigational Medicinal Product</classLabel>
<newAxiom>'Authorized Investigational Medicinal Product' SubClassOf 'Medicinal Product'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156616</classIRI>
<classLabel>SEND Developmental and Reproductive Toxicology Implementation Guide Version 1.1</classLabel>
<newAxiom>'SEND Developmental and Reproductive Toxicology Implementation Guide Version 1.1' SubClassOf 'Version'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156615</classIRI>
<classLabel>Physiologic Antagonist</classLabel>
<newAxiom>'Physiologic Antagonist' SubClassOf 'Antagonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156689</classIRI>
<classLabel>Advanced Small Intestinal Large Cell Neuroendocrine Carcinoma</classLabel>
<newAxiom>'Advanced Small Intestinal Large Cell Neuroendocrine Carcinoma' EquivalentTo 'Advanced Small Intestinal Neuroendocrine Carcinoma' and 'Small Intestinal Large Cell Neuroendocrine Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156688</classIRI>
<classLabel>Advanced Small Intestinal Small Cell Neuroendocrine Carcinoma</classLabel>
<newAxiom>'Advanced Small Intestinal Small Cell Neuroendocrine Carcinoma' EquivalentTo 'Advanced Small Intestinal Neuroendocrine Carcinoma' and 'Small Intestinal Small Cell Neuroendocrine Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156687</classIRI>
<classLabel>Advanced Small Intestinal Neuroendocrine Carcinoma</classLabel>
<newAxiom>'Advanced Small Intestinal Neuroendocrine Carcinoma' EquivalentTo 'Advanced Neuroendocrine Carcinoma' and 'Metastatic Small Intestinal Neuroendocrine Carcinoma' and 'Advanced Digestive System Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156686</classIRI>
<classLabel>Metastatic Small Intestinal Neuroendocrine Carcinoma</classLabel>
<newAxiom>'Metastatic Small Intestinal Neuroendocrine Carcinoma' EquivalentTo 'Metastatic Digestive System Neuroendocrine Carcinoma' and 'Metastatic Small Intestinal Carcinoma' and 'Small Intestinal Neuroendocrine Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156685</classIRI>
<classLabel>Advanced Gastric Small Cell Neuroendocrine Carcinoma</classLabel>
<newAxiom>'Advanced Gastric Small Cell Neuroendocrine Carcinoma' EquivalentTo 'Advanced Gastric Neuroendocrine Carcinoma' and 'Gastric Small Cell Neuroendocrine Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156684</classIRI>
<classLabel>Advanced Gastric Large Cell Neuroendocrine Carcinoma</classLabel>
<newAxiom>'Advanced Gastric Large Cell Neuroendocrine Carcinoma' EquivalentTo 'Advanced Gastric Neuroendocrine Carcinoma' and 'Gastric Large Cell Neuroendocrine Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156694</classIRI>
<classLabel>Antitumor B Key Active Component-alpha</classLabel>
<newAxiom>'Antitumor B Key Active Component-alpha' SubClassOf 'Dietary Supplement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156693</classIRI>
<classLabel>ECT-001 Expanded Cord Blood</classLabel>
<newAxiom>'ECT-001 Expanded Cord Blood' SubClassOf 'Adoptive Cell Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156692</classIRI>
<classLabel>Anti-PD-L1 Monoclonal Antibody CBT-502</classLabel>
<newAxiom>'Anti-PD-L1 Monoclonal Antibody CBT-502' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-PD-L1 Monoclonal Antibody CBT-502' SubClassOf 'Anti-PD-L1 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156691</classIRI>
<classLabel>Factor B Inhibitor LNP023</classLabel>
<newAxiom>'Factor B Inhibitor LNP023' SubClassOf 'Immunotherapeutic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156690</classIRI>
<classLabel>Blasts 25 Percent or Less of Bone Marrow Nucleated Cells</classLabel>
<newAxiom>'Blasts 25 Percent or Less of Bone Marrow Nucleated Cells' SubClassOf 'Blasts 30 Percent or Less of Bone Marrow Nucleated Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156699</classIRI>
<classLabel>Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma</classLabel>
<newAxiom>'Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma' EquivalentTo 'Transformed Non-Hodgkin Lymphoma' and 'Mature B-Cell Non-Hodgkin Lymphoma' and ('Disease_Has_Normal_Tissue_Origin' some 'Marginal Zone') and ('Disease_Has_Abnormal_Cell' some 'Neoplastic Large B-Lymphocyte')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156698</classIRI>
<classLabel>Rhenium Re-188 Etidronate</classLabel>
<newAxiom>'Rhenium Re-188 Etidronate' SubClassOf 'Antineoplastic Radiopharmaceutical Agent'</newAxiom>
<newAxiom>'Rhenium Re-188 Etidronate' SubClassOf 'Radioconjugate'</newAxiom>
<newAxiom>'Rhenium Re-188 Etidronate' SubClassOf 'Adjuvant Analgesic'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156697</classIRI>
<classLabel>Halichondrin Analogue E7130</classLabel>
<newAxiom>'Halichondrin Analogue E7130' SubClassOf 'Vinca-Domain Binding Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156696</classIRI>
<classLabel>Recurrent T-Cell/Histiocyte-Rich Large B-Cell Lymphoma</classLabel>
<newAxiom>'Recurrent T-Cell/Histiocyte-Rich Large B-Cell Lymphoma' EquivalentTo 'Recurrent Diffuse Large B-Cell Lymphoma' and 'T-Cell/Histiocyte-Rich Large B-Cell Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156695</classIRI>
<classLabel>SHP-1 Agonist SC-43</classLabel>
<newAxiom>'SHP-1 Agonist SC-43' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156669</classIRI>
<classLabel>Immunoglobulin-Like Domain-Containing Receptor 2</classLabel>
<newAxiom>'Immunoglobulin-Like Domain-Containing Receptor 2' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'Immunoglobulin-Like V-Type Domain'</newAxiom>
<newAxiom>'Immunoglobulin-Like Domain-Containing Receptor 2' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Cellular Membrane'</newAxiom>
<newAxiom>'Immunoglobulin-Like Domain-Containing Receptor 2' SubClassOf 'Receptor'</newAxiom>
<newAxiom>'Immunoglobulin-Like Domain-Containing Receptor 2' SubClassOf 'Gene_Product_Has_Biochemical_Function' some 'Transmembrane Protein'</newAxiom>
<newAxiom>'Immunoglobulin-Like Domain-Containing Receptor 2' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'ILDR2 Gene'</newAxiom>
<newAxiom>'Immunoglobulin-Like Domain-Containing Receptor 2' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156668</classIRI>
<classLabel>ILDR2 wt Allele</classLabel>
<newAxiom>'ILDR2 wt Allele' SubClassOf 'ILDR2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156667</classIRI>
<classLabel>ILDR2 Gene</classLabel>
<newAxiom>'ILDR2 Gene' SubClassOf 'Receptor Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156666</classIRI>
<classLabel>Microneedle Drug Delivery System</classLabel>
<newAxiom>'Microneedle Drug Delivery System' SubClassOf 'Drug Delivery System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156665</classIRI>
<classLabel>Micro Needle Array-Doxorubicin</classLabel>
<newAxiom>'Micro Needle Array-Doxorubicin' SubClassOf 'Doxorubicin Preparation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156664</classIRI>
<classLabel>Non-Neoplastic Genitourinary System Disorder</classLabel>
<newAxiom>'Non-Neoplastic Genitourinary System Disorder' SubClassOf 'Disease_Has_Primary_Anatomic_Site' some 'Genitourinary System'</newAxiom>
<newAxiom>'Non-Neoplastic Genitourinary System Disorder' SubClassOf 'Genitourinary System Disorder'</newAxiom>
<newAxiom>'Non-Neoplastic Genitourinary System Disorder' SubClassOf 'Non-Neoplastic Disorder by Site'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156663</classIRI>
<classLabel>Minor Person</classLabel>
<newAxiom>'Minor Person' SubClassOf 'Person'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156662</classIRI>
<classLabel>Small for Gestational Age Indicator</classLabel>
<newAxiom>'Small for Gestational Age Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156672</classIRI>
<classLabel>CDISC Clinical Classification COVI Test Name Terminology</classLabel>
<newAxiom>'CDISC Clinical Classification COVI Test Name Terminology' SubClassOf 'CDISC Clinical Classification Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156671</classIRI>
<classLabel>Steroid-Refractory Pneumonitis</classLabel>
<newAxiom>'Steroid-Refractory Pneumonitis' SubClassOf 'Pneumonitis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156670</classIRI>
<classLabel>Blasts More than 15 Percent of Bone Marrow Nucleated Cells</classLabel>
<newAxiom>'Blasts More than 15 Percent of Bone Marrow Nucleated Cells' SubClassOf 'Blasts 10 Percent or More of Bone Marrow Nucleated Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156679</classIRI>
<classLabel>COVI - Total Score</classLabel>
<newAxiom>'COVI - Total Score' SubClassOf 'COVI Clinical Classification Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156678</classIRI>
<classLabel>COVI - Somatic Symptoms of Anxiety</classLabel>
<newAxiom>'COVI - Somatic Symptoms of Anxiety' SubClassOf 'COVI Clinical Classification Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156677</classIRI>
<classLabel>COVI - Behavior</classLabel>
<newAxiom>'COVI - Behavior' SubClassOf 'COVI Clinical Classification Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156676</classIRI>
<classLabel>COVI - Verbal Report</classLabel>
<newAxiom>'COVI - Verbal Report' SubClassOf 'COVI Clinical Classification Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156675</classIRI>
<classLabel>Covi Anxiety Scale Clinical Classification</classLabel>
<newAxiom>'Covi Anxiety Scale Clinical Classification' SubClassOf 'Clinical Classification'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156674</classIRI>
<classLabel>COVI Clinical Classification Question</classLabel>
<newAxiom>'COVI Clinical Classification Question' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156673</classIRI>
<classLabel>CDISC Clinical Classification COVI Test Code Terminology</classLabel>
<newAxiom>'CDISC Clinical Classification COVI Test Code Terminology' SubClassOf 'CDISC Clinical Classification Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156683</classIRI>
<classLabel>Advanced Gastric Neuroendocrine Carcinoma</classLabel>
<newAxiom>'Advanced Gastric Neuroendocrine Carcinoma' EquivalentTo 'Advanced Neuroendocrine Carcinoma' and 'Metastatic Gastric Neuroendocrine Carcinoma' and 'Advanced Digestive System Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156682</classIRI>
<classLabel>Metastatic Gastric Neuroendocrine Carcinoma</classLabel>
<newAxiom>'Metastatic Gastric Neuroendocrine Carcinoma' EquivalentTo 'Metastatic Gastric Carcinoma' and 'Metastatic Digestive System Neuroendocrine Carcinoma' and 'Gastric Neuroendocrine Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156681</classIRI>
<classLabel>PSMA/CD3 Tri-specific T-cell Activating Construct HPN424</classLabel>
<newAxiom>'PSMA/CD3 Tri-specific T-cell Activating Construct HPN424' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156680</classIRI>
<classLabel>Nucleotide Analog Prodrug NUC-3373</classLabel>
<newAxiom>'Nucleotide Analog Prodrug NUC-3373' SubClassOf 'Thymidylate Synthase Inhibitor'</newAxiom>
<newAxiom>'Nucleotide Analog Prodrug NUC-3373' SubClassOf 'Pyrimidine Antagonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156489</classIRI>
<classLabel>Advanced Pancreatic Neuroendocrine Tumor</classLabel>
<newAxiom>'Advanced Pancreatic Neuroendocrine Tumor' EquivalentTo 'Advanced Well Differentiated Neuroendocrine Neoplasm' and 'Metastatic Pancreatic Neuroendocrine Tumor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156488</classIRI>
<classLabel>Metastatic Pancreatic Neuroendocrine Tumor</classLabel>
<newAxiom>'Metastatic Pancreatic Neuroendocrine Tumor' EquivalentTo 'Metastatic Well Differentiated Neuroendocrine Neoplasm' and 'Metastatic Malignant Pancreatic Neoplasm' and 'Metastatic Digestive System Neuroendocrine Neoplasm' and 'Pancreatic Neuroendocrine Tumor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156487</classIRI>
<classLabel>Advanced Carcinoid Tumor</classLabel>
<newAxiom>'Advanced Carcinoid Tumor' EquivalentTo 'Advanced Well Differentiated Neuroendocrine Neoplasm' and 'Metastatic Carcinoid Tumor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156486</classIRI>
<classLabel>Advanced Neuroendocrine Neoplasm</classLabel>
<newAxiom>'Advanced Neuroendocrine Neoplasm' EquivalentTo 'Metastatic Neuroendocrine Neoplasm' and 'Advanced Malignant Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156496</classIRI>
<classLabel>Spectral Width</classLabel>
<newAxiom>'Spectral Width' SubClassOf 'Width'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156495</classIRI>
<classLabel>Number of Unsuppressed Water Averages</classLabel>
<newAxiom>'Number of Unsuppressed Water Averages' SubClassOf 'Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156494</classIRI>
<classLabel>Magnetic Field Strength</classLabel>
<newAxiom>'Magnetic Field Strength' SubClassOf 'Medical Device Attribute'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156493</classIRI>
<classLabel>Metastatic Breast Neuroendocrine Neoplasm</classLabel>
<newAxiom>'Metastatic Breast Neuroendocrine Neoplasm' EquivalentTo 'Metastatic Neuroendocrine Neoplasm' and 'Breast Neuroendocrine Neoplasm' and 'Malignant Breast Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156492</classIRI>
<classLabel>Metastatic Digestive System Neuroendocrine Neoplasm</classLabel>
<newAxiom>'Metastatic Digestive System Neuroendocrine Neoplasm' EquivalentTo 'Metastatic Neuroendocrine Neoplasm' and 'Digestive System Neuroendocrine Neoplasm' and 'Malignant Digestive System Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156490</classIRI>
<classLabel>Anti-ILDR2 Monoclonal Antibody BAY 1905254</classLabel>
<newAxiom>'Anti-ILDR2 Monoclonal Antibody BAY 1905254' SubClassOf 'Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-ILDR2 Monoclonal Antibody BAY 1905254' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156499</classIRI>
<classLabel>Z-Axis Voxel Dimension</classLabel>
<newAxiom>'Z-Axis Voxel Dimension' SubClassOf 'Voxel Size'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156498</classIRI>
<classLabel>Y-Axis Voxel Dimension</classLabel>
<newAxiom>'Y-Axis Voxel Dimension' SubClassOf 'Voxel Size'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156497</classIRI>
<classLabel>X-Axis Voxel Dimension</classLabel>
<newAxiom>'X-Axis Voxel Dimension' SubClassOf 'Voxel Size'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156479</classIRI>
<classLabel>Autologous iC9-deltaNGFR-CD19CAR-CD3zeta-4-1BB-expressing T-lymphocytes</classLabel>
<newAxiom>'Autologous iC9-deltaNGFR-CD19CAR-CD3zeta-4-1BB-expressing T-lymphocytes' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous iC9-deltaNGFR-CD19CAR-CD3zeta-4-1BB-expressing T-lymphocytes' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Autologous iC9-deltaNGFR-CD19CAR-CD3zeta-4-1BB-expressing T-lymphocytes' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156485</classIRI>
<classLabel>Metastatic Neuroendocrine Neoplasm</classLabel>
<newAxiom>'Metastatic Neuroendocrine Neoplasm' EquivalentTo 'Metastatic Malignant Neoplasm' and 'Neuroendocrine Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156484</classIRI>
<classLabel>Malignant Genitourinary System Neoplasm</classLabel>
<newAxiom>'Malignant Genitourinary System Neoplasm' EquivalentTo 'Genitourinary System Neoplasm' and 'Malignant Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156483</classIRI>
<classLabel>Benign Genitourinary System Neoplasm</classLabel>
<newAxiom>'Benign Genitourinary System Neoplasm' EquivalentTo 'Genitourinary System Neoplasm' and 'Benign Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Genitourinary System')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156482</classIRI>
<classLabel>Genitourinary System Neoplasm</classLabel>
<newAxiom>'Genitourinary System Neoplasm' EquivalentTo 'Genitourinary System Disorder' and 'Neoplasm by Site'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156481</classIRI>
<classLabel>Young Autologous Tumor-infiltrating Lymphocytes</classLabel>
<newAxiom>'Young Autologous Tumor-infiltrating Lymphocytes' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Young Autologous Tumor-infiltrating Lymphocytes' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156480</classIRI>
<classLabel>Anti-HER2 Antibody-drug Conjugate A166</classLabel>
<newAxiom>'Anti-HER2 Antibody-drug Conjugate A166' SubClassOf 'Anti-HER2 Antibody-drug Conjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156988</classIRI>
<classLabel>Go Jogging or Running</classLabel>
<newAxiom>'Go Jogging or Running' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156987</classIRI>
<classLabel>Work on Car, Truck, Lawn Mower, or Other Machinery</classLabel>
<newAxiom>'Work on Car, Truck, Lawn Mower, or Other Machinery' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156986</classIRI>
<classLabel>Do Light Gardening</classLabel>
<newAxiom>'Do Light Gardening' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156985</classIRI>
<classLabel>Do Heavy Gardening</classLabel>
<newAxiom>'Do Heavy Gardening' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156984</classIRI>
<classLabel>Do Light Work Around the House</classLabel>
<newAxiom>'Do Light Work Around the House' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156983</classIRI>
<classLabel>Do Heavy Work Around the House</classLabel>
<newAxiom>'Do Heavy Work Around the House' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156982</classIRI>
<classLabel>Do Reading</classLabel>
<newAxiom>'Do Reading' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156981</classIRI>
<classLabel>Play a Musical Instrument</classLabel>
<newAxiom>'Play a Musical Instrument' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156989</classIRI>
<classLabel>Walk or Hike Uphill</classLabel>
<newAxiom>'Walk or Hike Uphill' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156991</classIRI>
<classLabel>Walk to Do Errands</classLabel>
<newAxiom>'Walk to Do Errands' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156990</classIRI>
<classLabel>Walk Fast or Briskly for Exercise</classLabel>
<newAxiom>'Walk Fast or Briskly for Exercise' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156999</classIRI>
<classLabel>Do Yoga or Tai-chi</classLabel>
<newAxiom>'Do Yoga or Tai-chi' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156998</classIRI>
<classLabel>Do Stretching or Flexibility Exercises</classLabel>
<newAxiom>'Do Stretching or Flexibility Exercises' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156997</classIRI>
<classLabel>Swim Gently</classLabel>
<newAxiom>'Swim Gently' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156996</classIRI>
<classLabel>Swim Moderately or Fast</classLabel>
<newAxiom>'Swim Moderately or Fast' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156995</classIRI>
<classLabel>Do Water Exercises Other than Swimming</classLabel>
<newAxiom>'Do Water Exercises Other than Swimming' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156994</classIRI>
<classLabel>Use Other Aerobic Equipment</classLabel>
<newAxiom>'Use Other Aerobic Equipment' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156993</classIRI>
<classLabel>Ride a Bicycle or Stationary Bike</classLabel>
<newAxiom>'Ride a Bicycle or Stationary Bike' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156992</classIRI>
<classLabel>Walk Leisurely for Exercise or Pleasure</classLabel>
<newAxiom>'Walk Leisurely for Exercise or Pleasure' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156966</classIRI>
<classLabel>CPTAC Malignant Neoplasm List Terminology</classLabel>
<newAxiom>'CPTAC Malignant Neoplasm List Terminology' SubClassOf 'CPTAC Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156965</classIRI>
<classLabel>Do Artwork or Crafts</classLabel>
<newAxiom>'Do Artwork or Crafts' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156964</classIRI>
<classLabel>Do You Dance</classLabel>
<newAxiom>'Do You Dance' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156963</classIRI>
<classLabel>Use a Computer</classLabel>
<newAxiom>'Use a Computer' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156962</classIRI>
<classLabel>Attend Other Club or Group Meetings</classLabel>
<newAxiom>'Attend Other Club or Group Meetings' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156961</classIRI>
<classLabel>Attend Church or Take Part in Church Activities</classLabel>
<newAxiom>'Attend Church or Take Part in Church Activities' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156960</classIRI>
<classLabel>Do Volunteer Work</classLabel>
<newAxiom>'Do Volunteer Work' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156969</classIRI>
<classLabel>GDP-L-Fucose Synthase</classLabel>
<newAxiom>'GDP-L-Fucose Synthase' EquivalentTo 'Oxidoreductase' and ('Gene_Product_Is_Element_In_Pathway' some 'Fructose and Mannose Metabolism Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Amino and Nucleotide Sugars Metabolism Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Exosome') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytosol') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Biosynthetic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Carbohydrate Metabolic Process') and ('Gene_Product_Encoded_By_Gene' some 'TSTA3 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156968</classIRI>
<classLabel>TSTA3 wt Allele</classLabel>
<newAxiom>'TSTA3 wt Allele' EquivalentTo 'TSTA3 Gene' and ('Gene_Is_Element_In_Pathway' some 'Fructose and Mannose Metabolism Pathway') and ('Gene_Is_Element_In_Pathway' some 'Amino and Nucleotide Sugars Metabolism Pathway') and ('Gene_In_Chromosomal_Location' some '8q24.3')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156967</classIRI>
<classLabel>TSTA3 Gene</classLabel>
<newAxiom>'TSTA3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Carbohydrate Metabolic Process'</newAxiom>
<newAxiom>'TSTA3 Gene' SubClassOf 'Oxidoreductase Gene'</newAxiom>
<newAxiom>'TSTA3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Biosynthetic Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156977</classIRI>
<classLabel>Shoot Pool or Billiards</classLabel>
<newAxiom>'Shoot Pool or Billiards' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156976</classIRI>
<classLabel>Play Cards, Bingo, or Board Games with Other People</classLabel>
<newAxiom>'Play Cards, Bingo, or Board Games with Other People' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156975</classIRI>
<classLabel>Attend Concert, Movie, Lecture or Sport Event</classLabel>
<newAxiom>'Attend Concert, Movie, Lecture or Sport Event' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156974</classIRI>
<classLabel>Play Golf, Riding Cart</classLabel>
<newAxiom>'Play Golf, Riding Cart' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156973</classIRI>
<classLabel>Play Golf and Carry Own Equipment</classLabel>
<newAxiom>'Play Golf and Carry Own Equipment' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156972</classIRI>
<classLabel>Battenin</classLabel>
<newAxiom>'Battenin' EquivalentTo 'Transport Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Lysosome Assembly Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Endosome') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Lysosome') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Transmembrane Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Intracellular Transport') and ('Gene_Product_Encoded_By_Gene' some 'CLN3 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156971</classIRI>
<classLabel>CLN3 wt Allele</classLabel>
<newAxiom>'CLN3 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '16p12.1'</newAxiom>
<newAxiom>'CLN3 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Lysosome Assembly Pathway'</newAxiom>
<newAxiom>'CLN3 wt Allele' SubClassOf 'CLN3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156970</classIRI>
<classLabel>CLN3 Gene</classLabel>
<newAxiom>'CLN3 Gene' SubClassOf 'Trafficking Protein Gene'</newAxiom>
<newAxiom>'CLN3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Intracellular Transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156979</classIRI>
<classLabel>Play Doubles Tennis</classLabel>
<newAxiom>'Play Doubles Tennis' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156978</classIRI>
<classLabel>Play Singles Tennis</classLabel>
<newAxiom>'Play Singles Tennis' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156980</classIRI>
<classLabel>Go Skating</classLabel>
<newAxiom>'Go Skating' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156944</classIRI>
<classLabel>Adrenal Gland Schwannoma</classLabel>
<newAxiom>'Adrenal Gland Schwannoma' EquivalentTo 'Schwannoma' and 'Benign Adrenal Medulla Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156943</classIRI>
<classLabel>Adrenal Cortex Sex Cord-Stromal Tumor</classLabel>
<newAxiom>'Adrenal Cortex Sex Cord-Stromal Tumor' EquivalentTo 'Adrenal Cortex Neoplasm' and 'Sex Cord-Stromal Tumor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156942</classIRI>
<classLabel>Ubl Carboxyl-Terminal Hydrolase 18</classLabel>
<newAxiom>'Ubl Carboxyl-Terminal Hydrolase 18' EquivalentTo 'Cysteine Proteinase' and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Inflammatory Response') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Interferon Signaling Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Cleavage') and ('Gene_Product_Encoded_By_Gene' some 'USP18 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156941</classIRI>
<classLabel>USP18 wt Allele</classLabel>
<newAxiom>'USP18 wt Allele' SubClassOf 'USP18 Gene'</newAxiom>
<newAxiom>'USP18 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '22q11.2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156940</classIRI>
<classLabel>USP18 Gene</classLabel>
<newAxiom>'USP18 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Cleavage'</newAxiom>
<newAxiom>'USP18 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Interferon Signaling Process'</newAxiom>
<newAxiom>'USP18 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Inflammatory Response'</newAxiom>
<newAxiom>'USP18 Gene' SubClassOf 'Cysteine Peptidase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156949</classIRI>
<classLabel>Between 5 and 6.5 Hours</classLabel>
<newAxiom>'Between 5 and 6.5 Hours' SubClassOf 'Period'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156948</classIRI>
<classLabel>Between 3 and 4.5 Hours</classLabel>
<newAxiom>'Between 3 and 4.5 Hours' SubClassOf 'Period'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156947</classIRI>
<classLabel>Between 1 and 2.5 Hours</classLabel>
<newAxiom>'Between 1 and 2.5 Hours' SubClassOf 'Period'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156946</classIRI>
<classLabel>Less than 1 hour</classLabel>
<newAxiom>'Less than 1 hour' SubClassOf 'Period'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156945</classIRI>
<classLabel>Adrenal Gland Lymphoma</classLabel>
<newAxiom>'Adrenal Gland Lymphoma' EquivalentTo 'Lymphoma by Site' and 'Malignant Adrenal Gland Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Adrenal Gland')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156955</classIRI>
<classLabel>CPTAC Follow-Up Form Terminology</classLabel>
<newAxiom>'CPTAC Follow-Up Form Terminology' SubClassOf 'CPTAC Medical Forms Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156954</classIRI>
<classLabel>CPTAC Medical History Form 1</classLabel>
<newAxiom>'CPTAC Medical History Form 1' SubClassOf 'CPTAC Medical Forms Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156953</classIRI>
<classLabel>CPTAC Medical Forms Terminology</classLabel>
<newAxiom>'CPTAC Medical Forms Terminology' SubClassOf 'CPTAC Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952</classIRI>
<classLabel>CPTAC Terminology</classLabel>
<newAxiom>'CPTAC Terminology' SubClassOf 'Terminology Subset'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156951</classIRI>
<classLabel>More than 9 Hours</classLabel>
<newAxiom>'More than 9 Hours' SubClassOf 'Period'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156950</classIRI>
<classLabel>Between 7 and 8.5 Hours</classLabel>
<newAxiom>'Between 7 and 8.5 Hours' SubClassOf 'Period'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156959</classIRI>
<classLabel>Go to Senior Center</classLabel>
<newAxiom>'Go to Senior Center' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156958</classIRI>
<classLabel>Visit with Friends or Family</classLabel>
<newAxiom>'Visit with Friends or Family' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156957</classIRI>
<classLabel>CHAMPS Activities Questionnaire for Older Adults</classLabel>
<newAxiom>'CHAMPS Activities Questionnaire for Older Adults' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156956</classIRI>
<classLabel>Adrenal Gland Sarcoma</classLabel>
<newAxiom>'Adrenal Gland Sarcoma' EquivalentTo 'Soft Tissue Sarcoma' and 'Malignant Adrenal Gland Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Adrenal Gland')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156922</classIRI>
<classLabel>PBAF Complex</classLabel>
<newAxiom>'PBAF Complex' SubClassOf 'hSWI/SNF Complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156921</classIRI>
<classLabel>Neural Progenitors-Specific BAF Complex</classLabel>
<newAxiom>'Neural Progenitors-Specific BAF Complex' SubClassOf 'hSWI/SNF Complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156920</classIRI>
<classLabel>Neuron-Specific BAF Complex</classLabel>
<newAxiom>'Neuron-Specific BAF Complex' SubClassOf 'hSWI/SNF Complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156929</classIRI>
<classLabel>Peptidyl-Prolyl Cis-Trans Isomerase A</classLabel>
<newAxiom>'Peptidyl-Prolyl Cis-Trans Isomerase A' EquivalentTo 'Isomerase' and ('Gene_Product_Is_Element_In_Pathway' some 'IL2RB Pathway') and ('Gene_Product_Has_Biochemical_Function' some 'Chaperone') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Folding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immunoregulation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Virus Replication Cycle') and ('Gene_Product_Encoded_By_Gene' some 'PPIA Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156928</classIRI>
<classLabel>PPIA wt Allele</classLabel>
<newAxiom>'PPIA wt Allele' EquivalentTo 'PPIA Gene' and ('Gene_Is_Element_In_Pathway' some 'IL2RB Pathway') and ('Gene_In_Chromosomal_Location' some '7p13')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156927</classIRI>
<classLabel>PPIA Gene</classLabel>
<newAxiom>'PPIA Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immunoregulation'</newAxiom>
<newAxiom>'PPIA Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Folding'</newAxiom>
<newAxiom>'PPIA Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Virus Replication Cycle'</newAxiom>
<newAxiom>'PPIA Gene' SubClassOf 'Isomerase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156926</classIRI>
<classLabel>mRNA-based Tumor-specific Neoantigen Boosting Vaccine GRT-R902</classLabel>
<newAxiom>'mRNA-based Tumor-specific Neoantigen Boosting Vaccine GRT-R902' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'T-Cell Activation'</newAxiom>
<newAxiom>'mRNA-based Tumor-specific Neoantigen Boosting Vaccine GRT-R902' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Regulation of Antibody Titer Process'</newAxiom>
<newAxiom>'mRNA-based Tumor-specific Neoantigen Boosting Vaccine GRT-R902' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Immunopotentiation'</newAxiom>
<newAxiom>'mRNA-based Tumor-specific Neoantigen Boosting Vaccine GRT-R902' SubClassOf 'Antineoplastic Vaccine'</newAxiom>
<newAxiom>'mRNA-based Tumor-specific Neoantigen Boosting Vaccine GRT-R902' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Antibody-Dependent Cellular Cytotoxicity'</newAxiom>
<newAxiom>'mRNA-based Tumor-specific Neoantigen Boosting Vaccine GRT-R902' SubClassOf 'Chemical_Or_Drug_Has_Mechanism_Of_Action' some 'Antigen Sensitization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156925</classIRI>
<classLabel>Adenoviral Tumor-specific Neoantigen Priming Vaccine GRT-C901</classLabel>
<newAxiom>'Adenoviral Tumor-specific Neoantigen Priming Vaccine GRT-C901' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'T-Cell Activation'</newAxiom>
<newAxiom>'Adenoviral Tumor-specific Neoantigen Priming Vaccine GRT-C901' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Regulation of Antibody Titer Process'</newAxiom>
<newAxiom>'Adenoviral Tumor-specific Neoantigen Priming Vaccine GRT-C901' SubClassOf 'Chemical_Or_Drug_Has_Mechanism_Of_Action' some 'Antigen Sensitization'</newAxiom>
<newAxiom>'Adenoviral Tumor-specific Neoantigen Priming Vaccine GRT-C901' SubClassOf 'Antineoplastic Vaccine'</newAxiom>
<newAxiom>'Adenoviral Tumor-specific Neoantigen Priming Vaccine GRT-C901' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Immunopotentiation'</newAxiom>
<newAxiom>'Adenoviral Tumor-specific Neoantigen Priming Vaccine GRT-C901' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Antibody-Dependent Cellular Cytotoxicity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156923</classIRI>
<classLabel>Non-Canonical BAF Complex</classLabel>
<newAxiom>'Non-Canonical BAF Complex' SubClassOf 'hSWI/SNF Complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156933</classIRI>
<classLabel>Human Anti-CD30 CAR-expressing Autologous T-lymphocytes</classLabel>
<newAxiom>'Human Anti-CD30 CAR-expressing Autologous T-lymphocytes' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Human Anti-CD30 CAR-expressing Autologous T-lymphocytes' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Human Anti-CD30 CAR-expressing Autologous T-lymphocytes' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156932</classIRI>
<classLabel>Methyltransferase-Like Protein 13</classLabel>
<newAxiom>'Methyltransferase-Like Protein 13' EquivalentTo 'Methyltransferase' and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Negative Regulation of Apoptosis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Methylation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Translation Process') and ('Gene_Product_Encoded_By_Gene' some 'EEF1AKNMT Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156931</classIRI>
<classLabel>EEF1AKNMT wt Allele</classLabel>
<newAxiom>'EEF1AKNMT wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '1q24.3'</newAxiom>
<newAxiom>'EEF1AKNMT wt Allele' SubClassOf 'EEF1AKNMT Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156930</classIRI>
<classLabel>EEF1AKNMT Gene</classLabel>
<newAxiom>'EEF1AKNMT Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Translation Process'</newAxiom>
<newAxiom>'EEF1AKNMT Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Methylation'</newAxiom>
<newAxiom>'EEF1AKNMT Gene' SubClassOf 'Methyltransferase Gene'</newAxiom>
<newAxiom>'EEF1AKNMT Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Negative Regulation of Apoptosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156939</classIRI>
<classLabel>Interfant-06 Protocol</classLabel>
<newAxiom>'Interfant-06 Protocol' SubClassOf 'Cancer Research'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156938</classIRI>
<classLabel>PRKACA Gene Mutation</classLabel>
<newAxiom>'PRKACA Gene Mutation' SubClassOf 'Gene Mutant'</newAxiom>
<newAxiom>'PRKACA Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'PRKACA Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156937</classIRI>
<classLabel>CACNA1D Gene Mutation</classLabel>
<newAxiom>'CACNA1D Gene Mutation' SubClassOf 'Gene Mutant'</newAxiom>
<newAxiom>'CACNA1D Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'CACNA1D Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156936</classIRI>
<classLabel>ATP2B3 Gene Mutation</classLabel>
<newAxiom>'ATP2B3 Gene Mutation' SubClassOf 'Gene Mutant'</newAxiom>
<newAxiom>'ATP2B3 Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'ATP2B3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156935</classIRI>
<classLabel>ATP1A1 Gene Mutation</classLabel>
<newAxiom>'ATP1A1 Gene Mutation' SubClassOf 'Gene Mutant'</newAxiom>
<newAxiom>'ATP1A1 Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'ATP1A1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156934</classIRI>
<classLabel>KCNJ5 Gene Mutation</classLabel>
<newAxiom>'KCNJ5 Gene Mutation' SubClassOf 'Gene Mutant'</newAxiom>
<newAxiom>'KCNJ5 Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'KCNJ5 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156900</classIRI>
<classLabel>HBB Gene Mutation</classLabel>
<newAxiom>'HBB Gene Mutation' SubClassOf 'Gene Mutant'</newAxiom>
<newAxiom>'HBB Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'HBB Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156908</classIRI>
<classLabel>Resectable Intrahepatic Cholangiocarcinoma</classLabel>
<newAxiom>'Resectable Intrahepatic Cholangiocarcinoma' EquivalentTo 'Resectable Cholangiocarcinoma' and 'Intrahepatic Cholangiocarcinoma' and 'Resectable Malignant Liver Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156907</classIRI>
<classLabel>Resectable Pancreatic Acinar Cell Carcinoma</classLabel>
<newAxiom>'Resectable Pancreatic Acinar Cell Carcinoma' EquivalentTo 'Resectable Pancreatic Adenocarcinoma' and 'Pancreatic Acinar Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156906</classIRI>
<classLabel>Resectable Pancreatic Adenocarcinoma</classLabel>
<newAxiom>'Resectable Pancreatic Adenocarcinoma' EquivalentTo 'Resectable Pancreatic Carcinoma' and 'Pancreatic Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156905</classIRI>
<classLabel>HBB NP_000509.1:p.E7V</classLabel>
<newAxiom>'HBB NP_000509.1:p.E7V' SubClassOf 'HBB Protein Variant'</newAxiom>
<newAxiom>'HBB NP_000509.1:p.E7V' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'HBB NM_000518.4:c.20AT'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156904</classIRI>
<classLabel>HBB NP_000509.1:p.E122K</classLabel>
<newAxiom>'HBB NP_000509.1:p.E122K' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'HBB NM_000518.4:c.364GA'</newAxiom>
<newAxiom>'HBB NP_000509.1:p.E122K' SubClassOf 'HBB Protein Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156903</classIRI>
<classLabel>HBB Protein Variant</classLabel>
<newAxiom>'HBB Protein Variant' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'HBB Gene'</newAxiom>
<newAxiom>'HBB Protein Variant' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'HBB Gene Mutation'</newAxiom>
<newAxiom>'HBB Protein Variant' SubClassOf 'Gene Product Sequence Variation'</newAxiom>
<newAxiom>'HBB Protein Variant' SubClassOf 'Gene_Product_Variant_Of_Gene_Product' some 'Hemoglobin Subunit Beta'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156902</classIRI>
<classLabel>HBB NM_000518.4:c.20AT</classLabel>
<newAxiom>'HBB NM_000518.4:c.20AT' SubClassOf 'HBB Gene Mutation'</newAxiom>
<newAxiom>'HBB NM_000518.4:c.20AT' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'HBB NP_000509.1:p.E7V'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156901</classIRI>
<classLabel>HBB NM_000518.4:c.364GA</classLabel>
<newAxiom>'HBB NM_000518.4:c.364GA' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'HBB NP_000509.1:p.E122K'</newAxiom>
<newAxiom>'HBB NM_000518.4:c.364GA' SubClassOf 'HBB Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156909</classIRI>
<classLabel>Resectable Digestive System Carcinoma</classLabel>
<newAxiom>'Resectable Digestive System Carcinoma' EquivalentTo 'Resectable Carcinoma' and 'Digestive System Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156911</classIRI>
<classLabel>Resectable Extrahepatic Bile Duct Adenocarcinoma</classLabel>
<newAxiom>'Resectable Extrahepatic Bile Duct Adenocarcinoma' EquivalentTo 'Resectable Bile Duct Adenocarcinoma' and 'Extrahepatic Bile Duct Adenocarcinoma' and 'Resectable Extrahepatic Bile Duct Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156910</classIRI>
<classLabel>Resectable Bile Duct Adenocarcinoma</classLabel>
<newAxiom>'Resectable Bile Duct Adenocarcinoma' EquivalentTo 'Resectable Digestive System Carcinoma' and 'Bile Duct Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156919</classIRI>
<classLabel>Canonical BAF Complex</classLabel>
<newAxiom>'Canonical BAF Complex' SubClassOf 'hSWI/SNF Complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156918</classIRI>
<classLabel>Number of Days from Date of Initial Cancer Diagnosis to Date of Last Contact</classLabel>
<newAxiom>'Number of Days from Date of Initial Cancer Diagnosis to Date of Last Contact' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156917</classIRI>
<classLabel>Duration of Follow-up in Months</classLabel>
<newAxiom>'Duration of Follow-up in Months' SubClassOf 'Duration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156916</classIRI>
<classLabel>Date of Last Contact</classLabel>
<newAxiom>'Date of Last Contact' SubClassOf 'Contact Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156915</classIRI>
<classLabel>Number of Days from Date of Initial Cancer Diagnosis to Date of Death</classLabel>
<newAxiom>'Number of Days from Date of Initial Cancer Diagnosis to Date of Death' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156914</classIRI>
<classLabel>Post-operative Therapy</classLabel>
<newAxiom>'Post-operative Therapy' SubClassOf 'Therapeutic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156913</classIRI>
<classLabel>Date of Performance Status Assessment</classLabel>
<newAxiom>'Date of Performance Status Assessment' SubClassOf 'Assessment Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156912</classIRI>
<classLabel>Tumor Status at Date of Last Contact or Death</classLabel>
<newAxiom>'Tumor Status at Date of Last Contact or Death' SubClassOf 'Tumor Status'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>