<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
190
</numberChangedClasses>
<numberNewClasses>
372
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C53182</classIRI>
<classLabel>Zygomaticus</classLabel>
<deletedAxiom>&apos;Zygomaticus&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Zygomaticus&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C119734</classIRI>
<classLabel>Peripheral Neuropathy</classLabel>
<newAxiom>&apos;Peripheral Neuropathy&apos; SubClassOf &apos;Peripheral Nervous System Disorder&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28305</classIRI>
<classLabel>Stage II Mesothelioma</classLabel>
<deletedAxiom>&apos;Stage II Mesothelioma&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Stage II Mesothelioma&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28306</classIRI>
<classLabel>Stage III Mesothelioma</classLabel>
<deletedAxiom>&apos;Stage III Mesothelioma&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Stage III Mesothelioma&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28307</classIRI>
<classLabel>Stage IV Mesothelioma</classLabel>
<deletedAxiom>&apos;Stage IV Mesothelioma&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Stage IV Mesothelioma&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28304</classIRI>
<classLabel>Stage I Mesothelioma</classLabel>
<deletedAxiom>&apos;Stage I Mesothelioma&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Stage I Mesothelioma&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28344</classIRI>
<classLabel>Alteration</classLabel>
<deletedAxiom>&apos;Alteration&apos; SubClassOf &apos;Conceptual Entity&apos;</deletedAxiom>
<newAxiom>&apos;Alteration&apos; SubClassOf &apos;Action&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87330</classIRI>
<classLabel>Asparagine Anhydrous</classLabel>
<deletedAxiom>&apos;Asparagine Anhydrous&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Asparagine Anhydrous&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48251</classIRI>
<classLabel>Protocol Deviation</classLabel>
<deletedAxiom>&apos;Protocol Deviation&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Protocol Deviation&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3800</classIRI>
<classLabel>Epithelioid Hemangioendothelioma</classLabel>
<deletedAxiom>&apos;Epithelioid Hemangioendothelioma&apos; EquivalentTo &apos;Hemangioendothelioma&apos; and &apos;Malignant Blood Vessel Neoplasm&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Epithelioid Endothelial Cell&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;WWTR1-CAMTA1 Fusion Protein Expression&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;t(1;3)(p36;q23-25)&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myxoid Stroma Formation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Hyalinized Stroma Formation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Low Grade Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Solitary Mass&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Painful Mass&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Borderline Lesion&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CAMTA1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;WWTR1/CAMTA1 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;WWTR1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Epithelioid Hemangioendothelioma&apos; EquivalentTo &apos;Hemangioendothelioma&apos; and &apos;Malignant Blood Vessel Neoplasm&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Epithelioid Endothelial Cell&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;WWTR1-CAMTA1 Fusion Protein Expression&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;t(1;3)(p36;q23-25)&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myxoid Stroma Formation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Hyalinized Stroma Formation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Low Grade Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Solitary Mass&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Painful Mass&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Borderline Lesion&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;WWTR1/CAMTA1 Fusion Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C93191</classIRI>
<classLabel>German Chamomile</classLabel>
<deletedAxiom>&apos;German Chamomile&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;German Chamomile&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C130999</classIRI>
<classLabel>Pearson Syndrome</classLabel>
<deletedAxiom>&apos;Pearson Syndrome&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Pearson Syndrome&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C130984</classIRI>
<classLabel>Chromosome 18q Deletion Syndrome</classLabel>
<deletedAxiom>&apos;Chromosome 18q Deletion Syndrome&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Chromosome 18q Deletion Syndrome&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68563</classIRI>
<classLabel>N-Telopeptide</classLabel>
<newAxiom>&apos;N-Telopeptide&apos; SubClassOf &apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Type I Collagen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20720</classIRI>
<classLabel>CDH3 Gene</classLabel>
<newAxiom>&apos;CDH3 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Calcium Binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20722</classIRI>
<classLabel>CDH5 Gene</classLabel>
<newAxiom>&apos;CDH5 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Calcium Binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20723</classIRI>
<classLabel>CDH13 Gene</classLabel>
<newAxiom>&apos;CDH13 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Calcium Binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C105602</classIRI>
<classLabel>WNK1 Gene</classLabel>
<newAxiom>&apos;WNK1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Serine/Threonine Phosphorylation&apos;</newAxiom>
<newAxiom>&apos;WNK1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Ion Transport Process&apos;</newAxiom>
<newAxiom>&apos;WNK1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Homeostatic Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C105604</classIRI>
<classLabel>Serine/Threonine-Protein Kinase WNK1</classLabel>
<deletedAxiom>&apos;Serine/Threonine-Protein Kinase WNK1&apos; SubClassOf &apos;Serine/Threonine Protein Kinase&apos;</deletedAxiom>
<deletedAxiom>&apos;Serine/Threonine-Protein Kinase WNK1&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;WNK1 Gene&apos;</deletedAxiom>
<newAxiom>&apos;Serine/Threonine-Protein Kinase WNK1&apos; EquivalentTo &apos;Serine/Threonine Protein Kinase&apos; and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Serine/Threonine Phosphorylation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Homeostatic Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;WNK1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54382</classIRI>
<classLabel>BRCATA wt Allele</classLabel>
<deletedAxiom>&apos;BRCATA wt Allele&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;BRCATA wt Allele&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54384</classIRI>
<classLabel>BRCD1 wt Allele</classLabel>
<deletedAxiom>&apos;BRCD1 wt Allele&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;BRCD1 wt Allele&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54375</classIRI>
<classLabel>BCPR wt Allele</classLabel>
<deletedAxiom>&apos;BCPR wt Allele&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;BCPR wt Allele&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54377</classIRI>
<classLabel>BRCA3 wt Allele</classLabel>
<deletedAxiom>&apos;BRCA3 wt Allele&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;BRCA3 wt Allele&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54409</classIRI>
<classLabel>HHCM wt Allele</classLabel>
<deletedAxiom>&apos;HHCM wt Allele&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;HHCM wt Allele&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118522</classIRI>
<classLabel>CHST15 Gene</classLabel>
<newAxiom>&apos;CHST15 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Biosynthetic Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118524</classIRI>
<classLabel>Carbohydrate Sulfotransferase 15</classLabel>
<deletedAxiom>&apos;Carbohydrate Sulfotransferase 15&apos; EquivalentTo &apos;Transferase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Glycosaminoglycan Biosynthesis Pathway - Chondroitin Sulfate&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Golgi Apparatus&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Sulfotransferase&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Carbohydrate Metabolic Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Protein Metabolism Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CHST15 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Carbohydrate Sulfotransferase 15&apos; EquivalentTo &apos;Transferase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Glycosaminoglycan Biosynthesis Pathway - Chondroitin Sulfate&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Golgi Apparatus&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Sulfotransferase&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Biosynthetic Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Carbohydrate Metabolic Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Protein Metabolism Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CHST15 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118389</classIRI>
<classLabel>IDH1 Gene Mutation</classLabel>
<newAxiom>&apos;IDH1 Gene Mutation&apos; SubClassOf &apos;Gene Mutant&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118390</classIRI>
<classLabel>IDH2 Gene Mutation</classLabel>
<newAxiom>&apos;IDH2 Gene Mutation&apos; SubClassOf &apos;Gene Mutant&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118394</classIRI>
<classLabel>MLH1 Gene Mutation</classLabel>
<newAxiom>&apos;MLH1 Gene Mutation&apos; SubClassOf &apos;Mismatch Repair Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118395</classIRI>
<classLabel>MSH6 Gene Mutation</classLabel>
<newAxiom>&apos;MSH6 Gene Mutation&apos; SubClassOf &apos;Mismatch Repair Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118397</classIRI>
<classLabel>PMS2 Gene Mutation</classLabel>
<newAxiom>&apos;PMS2 Gene Mutation&apos; SubClassOf &apos;Mismatch Repair Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40430</classIRI>
<classLabel>BRAF Gene Mutation</classLabel>
<newAxiom>&apos;BRAF Gene Mutation&apos; SubClassOf &apos;RAF Family Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88933</classIRI>
<classLabel>CUB and Sushi Domain-Containing Protein 1</classLabel>
<newAxiom>&apos;CUB and Sushi Domain-Containing Protein 1&apos; SubClassOf &apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;</newAxiom>
<newAxiom>&apos;CUB and Sushi Domain-Containing Protein 1&apos; SubClassOf &apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88985</classIRI>
<classLabel>CTNNA1 Gene</classLabel>
<deletedAxiom>&apos;CTNNA1 Gene&apos; SubClassOf &apos;Adaptor Signaling Protein Gene&apos;</deletedAxiom>
<newAxiom>&apos;CTNNA1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Cell-Cell Adhesion Process&apos;</newAxiom>
<newAxiom>&apos;CTNNA1 Gene&apos; SubClassOf &apos;Cytoskeletal Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88986</classIRI>
<classLabel>CTNNA1 wt Allele</classLabel>
<deletedAxiom>&apos;CTNNA1 wt Allele&apos; SubClassOf &apos;CTNNA1 Gene&apos;</deletedAxiom>
<deletedAxiom>&apos;CTNNA1 wt Allele&apos; SubClassOf &apos;Gene_In_Chromosomal_Location&apos; some &apos;5q31&apos;</deletedAxiom>
<newAxiom>&apos;CTNNA1 wt Allele&apos; EquivalentTo &apos;CTNNA1 Gene&apos; and (&apos;Gene_Is_Element_In_Pathway&apos; some &apos;Cell to Cell Adhesion Signaling Pathway&apos;) and (&apos;Gene_Is_Element_In_Pathway&apos; some &apos;Leukocyte Transendothelial Migration Pathway&apos;) and (&apos;Gene_Is_Element_In_Pathway&apos; some &apos;Arrhythmogenic Right Ventricular Cardiomyopathy Pathway&apos;) and (&apos;Gene_Is_Element_In_Pathway&apos; some &apos;Adherens Junction Assembly Pathway&apos;) and (&apos;Gene_Is_Element_In_Pathway&apos; some &apos;Endometrial Cancer Pathway&apos;) and (&apos;Gene_Is_Element_In_Pathway&apos; some &apos;Bacterial Invasion of Epithelial Cell Pathway&apos;) and (&apos;Gene_In_Chromosomal_Location&apos; some &apos;5q31&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88987</classIRI>
<classLabel>Catenin Alpha-1</classLabel>
<deletedAxiom>&apos;Catenin Alpha-1&apos; EquivalentTo &apos;Adaptor Signaling Protein&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Zonula Adherens&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Catenin Family Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Protein-Protein Interaction&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CTNNA1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Catenin Alpha-1&apos; EquivalentTo &apos;Cytoskeletal Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cell to Cell Adhesion Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Leukocyte Transendothelial Migration Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Arrhythmogenic Right Ventricular Cardiomyopathy Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Adherens Junction Assembly Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Endometrial Cancer Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Bacterial Invasion of Epithelial Cell Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cytoskeleton&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Zonula Adherens&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Catenin Family Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Protein-Protein Interaction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell-Cell Adhesion Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CTNNA1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49436</classIRI>
<classLabel>WT2 wt Allele</classLabel>
<deletedAxiom>&apos;WT2 wt Allele&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;WT2 wt Allele&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74517</classIRI>
<classLabel>RGS5 Gene</classLabel>
<deletedAxiom>&apos;RGS5 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Signal Transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137862</classIRI>
<classLabel>Refractory Pancreatic Neuroendocrine Carcinoma</classLabel>
<deletedAxiom>&apos;Refractory Pancreatic Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Refractory Abdominal Neuroendocrine Neoplasm&apos; and &apos;Refractory Pancreatic Carcinoma&apos; and &apos;Pancreatic Neuroendocrine Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Pancreatic Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Refractory Abdominal Neuroendocrine Neoplasm&apos; and &apos;Pancreatic Neuroendocrine Carcinoma&apos; and &apos;Refractory Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C60471</classIRI>
<classLabel>Rat Malignant Uveal Melanoma</classLabel>
<deletedAxiom>&apos;Rat Malignant Uveal Melanoma&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Rat Malignant Uveal Melanoma&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124129</classIRI>
<classLabel>Type I Collagen</classLabel>
<deletedAxiom>&apos;Type I Collagen&apos; SubClassOf &apos;Collagen&apos;</deletedAxiom>
<deletedAxiom>&apos;Type I Collagen&apos; SubClassOf &apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Protein or Riboprotein Complex&apos;</deletedAxiom>
<newAxiom>&apos;Type I Collagen&apos; SubClassOf &apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Collagen&apos;</newAxiom>
<newAxiom>&apos;Type I Collagen&apos; SubClassOf &apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Extracellular Matrix&apos;</newAxiom>
<newAxiom>&apos;Type I Collagen&apos; SubClassOf &apos;Protein or Riboprotein Complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21262</classIRI>
<classLabel>Breast Cancer, 11;22 Translocation Associated Protein</classLabel>
<deletedAxiom>&apos;Breast Cancer, 11;22 Translocation Associated Protein&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Breast Cancer, 11;22 Translocation Associated Protein&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21319</classIRI>
<classLabel>STAMBP Gene</classLabel>
<newAxiom>&apos;STAMBP Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Deubiquitination&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21339</classIRI>
<classLabel>STAM-Binding Protein</classLabel>
<deletedAxiom>&apos;STAM-Binding Protein&apos; EquivalentTo &apos;Metallopeptidase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Endocytosis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Internalization Pathway for Epidermal Growth Factor Receptor&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Nuclear Localization Signal&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;PXXP Motif&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Signaling Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Cycle Regulation Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;STAMBP Gene&apos;)</deletedAxiom>
<newAxiom>&apos;STAM-Binding Protein&apos; EquivalentTo &apos;Metallopeptidase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Endocytosis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Internalization Pathway for Epidermal Growth Factor Receptor&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Nuclear Localization Signal&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;PXXP Motif&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Signaling Protein&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Deubiquitinating Enzyme&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Cycle Regulation Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Deubiquitination&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;STAMBP Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21501</classIRI>
<classLabel>BRCD1 Protein</classLabel>
<deletedAxiom>&apos;BRCD1 Protein&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;BRCD1 Protein&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21504</classIRI>
<classLabel>BRCA3 Protein</classLabel>
<deletedAxiom>&apos;BRCA3 Protein&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;BRCA3 Protein&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138337</classIRI>
<classLabel>Functional Assessment of Cancer Therapy-Kidney Symptom Index-15 Questionnaire</classLabel>
<deletedAxiom>&apos;Functional Assessment of Cancer Therapy-Kidney Symptom Index-15 Questionnaire&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Functional Assessment of Cancer Therapy-Kidney Symptom Index-15 Questionnaire&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138057</classIRI>
<classLabel>Blasts Under 30 Percent of Bone Marrow Nucleated Cells</classLabel>
<deletedAxiom>&apos;Blasts Under 30 Percent of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blast Cells Increased in Bone Marrow&apos;</deletedAxiom>
<newAxiom>&apos;Blasts Under 30 Percent of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blasts 50 Percent or Less of Bone Marrow Nucleated Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138027</classIRI>
<classLabel>Recurrent Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type</classLabel>
<deletedAxiom>&apos;Recurrent Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; EquivalentTo &apos;Recurrent Primary Malignant Neoplasm&apos; and &apos;Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; and &apos;Recurrent Diffuse Large B-Cell Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142876 and &apos;Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; and &apos;Recurrent Diffuse Large B-Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138028</classIRI>
<classLabel>Refractory Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type</classLabel>
<deletedAxiom>&apos;Refractory Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; EquivalentTo &apos;Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; and &apos;Refractory Diffuse Large B-Cell Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142877 and &apos;Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; and &apos;Refractory Diffuse Large B-Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138188</classIRI>
<classLabel>Clinical Trials Search-Application Programming Interface Disease Category Terminology</classLabel>
<deletedAxiom>&apos;Clinical Trials Search-Application Programming Interface Disease Category Terminology&apos; SubClassOf &apos;Terminology Subset&apos;</deletedAxiom>
<newAxiom>&apos;Clinical Trials Search-Application Programming Interface Disease Category Terminology&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143048</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104486</classIRI>
<classLabel>GAGE3 Gene</classLabel>
<deletedAxiom>&apos;GAGE3 Gene&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;GAGE3 Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104487</classIRI>
<classLabel>GAGE3 wt Allele</classLabel>
<deletedAxiom>&apos;GAGE3 wt Allele&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;GAGE3 wt Allele&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104488</classIRI>
<classLabel>G Antigen 3</classLabel>
<deletedAxiom>&apos;G Antigen 3&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;G Antigen 3&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104200</classIRI>
<classLabel>Type III Procollagen N-Terminal Peptide</classLabel>
<deletedAxiom>&apos;Type III Procollagen N-Terminal Peptide&apos; SubClassOf &apos;Collagen&apos;</deletedAxiom>
<deletedAxiom>&apos;Type III Procollagen N-Terminal Peptide&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;Collagen Gene&apos;</deletedAxiom>
<newAxiom>&apos;Type III Procollagen N-Terminal Peptide&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143054</newAxiom>
<newAxiom>&apos;Type III Procollagen N-Terminal Peptide&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143052</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118889</classIRI>
<classLabel>Beta Isomer of C-Terminal Telopeptide of Type I Collagen</classLabel>
<newAxiom>&apos;Beta Isomer of C-Terminal Telopeptide of Type I Collagen&apos; SubClassOf &apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Type I Collagen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104396</classIRI>
<classLabel>Forkhead Box Protein P3</classLabel>
<deletedAxiom>&apos;Forkhead Box Protein P3&apos; SubClassOf &apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Forkhead Box&apos;</deletedAxiom>
<deletedAxiom>&apos;Forkhead Box Protein P3&apos; SubClassOf &apos;Transcription Factor&apos;</deletedAxiom>
<deletedAxiom>&apos;Forkhead Box Protein P3&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;FOXP3 Gene&apos;</deletedAxiom>
<newAxiom>&apos;Forkhead Box Protein P3&apos; EquivalentTo &apos;Transcription Factor&apos; and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;C2H2 Zinc Finger&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Forkhead Box&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Sequence-Specific DNA Binding Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Binding&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;T-Cell Differentiation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Regulation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;FOXP3 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118621</classIRI>
<classLabel>Ubidecarenone Injectable Nanosuspension</classLabel>
<newAxiom>&apos;Ubidecarenone Injectable Nanosuspension&apos; SubClassOf &apos;Antineoplastic Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16004</classIRI>
<classLabel>Plasma Enhancement</classLabel>
<deletedAxiom>&apos;Plasma Enhancement&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Plasma Enhancement&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41241</classIRI>
<classLabel>Blasts Under 10 Percent of Peripheral Blood White Cells</classLabel>
<deletedAxiom>&apos;Blasts Under 10 Percent of Peripheral Blood White Cells&apos; SubClassOf &apos;Blasts Under 20 Percent of Peripheral Blood White Cells&apos;</deletedAxiom>
<newAxiom>&apos;Blasts Under 10 Percent of Peripheral Blood White Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143152</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16373</classIRI>
<classLabel>Cadherin</classLabel>
<newAxiom>&apos;Cadherin&apos; SubClassOf &apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Calcium Binding Protein&apos;</newAxiom>
<newAxiom>&apos;Cadherin&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Calcium Binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41361</classIRI>
<classLabel>KRAS Gene Mutation</classLabel>
<newAxiom>&apos;KRAS Gene Mutation&apos; SubClassOf &apos;RAS Family Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41398</classIRI>
<classLabel>Blasts Under 10 Percent of Bone Marrow Nucleated Cells</classLabel>
<deletedAxiom>&apos;Blasts Under 10 Percent of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blasts Under 20 Percent of Bone Marrow Nucleated Cells&apos;</deletedAxiom>
<newAxiom>&apos;Blasts Under 10 Percent of Bone Marrow Nucleated Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143153</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41397</classIRI>
<classLabel>Blasts Under 20 Percent of Bone Marrow Nucleated Cells</classLabel>
<deletedAxiom>&apos;Blasts Under 20 Percent of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blast Cells Increased in Bone Marrow&apos;</deletedAxiom>
<newAxiom>&apos;Blasts Under 20 Percent of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blasts Under 25 Percent of Bone Marrow Nucleated Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41381</classIRI>
<classLabel>NRAS Gene Mutation</classLabel>
<newAxiom>&apos;NRAS Gene Mutation&apos; SubClassOf &apos;RAS Family Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132815</classIRI>
<classLabel>Stage 0 Nasopharyngeal Carcinoma AJCC v8</classLabel>
<deletedAxiom>&apos;Stage 0 Nasopharyngeal Carcinoma AJCC v8&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Stage 0 Nasopharyngeal Carcinoma AJCC v8&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107567</classIRI>
<classLabel>C-Telopeptide of Type I Collagen Generated by Matrix Metalloproteinases</classLabel>
<newAxiom>&apos;C-Telopeptide of Type I Collagen Generated by Matrix Metalloproteinases&apos; SubClassOf &apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Type I Collagen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16448</classIRI>
<classLabel>Collagen IV</classLabel>
<deletedAxiom>&apos;Collagen IV&apos; SubClassOf &apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Protein or Riboprotein Complex&apos;</deletedAxiom>
<deletedAxiom>&apos;Collagen IV&apos; SubClassOf &apos;Collagen&apos;</deletedAxiom>
<newAxiom>&apos;Collagen IV&apos; SubClassOf &apos;Protein or Riboprotein Complex&apos;</newAxiom>
<newAxiom>&apos;Collagen IV&apos; SubClassOf &apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Collagen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132280</classIRI>
<classLabel>Rhenium Re 186</classLabel>
<deletedAxiom>&apos;Rhenium Re 186&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Rhenium Re 186&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132006</classIRI>
<classLabel>RAD54L Gene Mutation</classLabel>
<deletedAxiom>&apos;RAD54L Gene Mutation&apos; SubClassOf &apos;Molecular_Abnormality_Involves_Gene&apos; some &apos;RAD51B Gene&apos;</deletedAxiom>
<newAxiom>&apos;RAD54L Gene Mutation&apos; SubClassOf &apos;Molecular_Abnormality_Involves_Gene&apos; some &apos;RAD54L Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36220</classIRI>
<classLabel>Blasts Under 20 Percent of Peripheral Blood White Cells</classLabel>
<deletedAxiom>&apos;Blasts Under 20 Percent of Peripheral Blood White Cells&apos; SubClassOf &apos;Blast Cells Present in Peripheral Blood&apos;</deletedAxiom>
<newAxiom>&apos;Blasts Under 20 Percent of Peripheral Blood White Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143154</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36216</classIRI>
<classLabel>Myeloblasts Under 20 Percent of Bone Marrow Nucleated Cells</classLabel>
<newAxiom>&apos;Myeloblasts Under 20 Percent of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Immature Myeloid Cells Increased in Bone Marrow&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17397</classIRI>
<classLabel>Oncogene ABL1</classLabel>
<deletedAxiom>&apos;Oncogene ABL1&apos; EquivalentTo &apos;Oncogenes, Protein-Kinase&apos; and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Cell Differentiation Process&apos;) and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Cell Division Process&apos;) and (&apos;Gene_Associated_With_Disease&apos; some &apos;Acute Lymphoblastic Leukemia&apos;) and (&apos;Gene_Associated_With_Disease&apos; some &apos;Acute Myeloid Leukemia&apos;) and (&apos;Gene_Associated_With_Disease&apos; some &apos;Chronic Myelogenous Leukemia, BCR-ABL1 Positive&apos;) and (&apos;Gene_In_Chromosomal_Location&apos; some &apos;9q34.1&apos;) and (&apos;Gene_Found_In_Organism&apos; some &apos;Human&apos;)</deletedAxiom>
<newAxiom>&apos;Oncogene ABL1&apos; EquivalentTo &apos;Oncogenes, Tyrosine-Kinase&apos; and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Cell Differentiation Process&apos;) and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Cell Division Process&apos;) and (&apos;Gene_Associated_With_Disease&apos; some &apos;Acute Lymphoblastic Leukemia&apos;) and (&apos;Gene_Associated_With_Disease&apos; some &apos;Acute Myeloid Leukemia&apos;) and (&apos;Gene_Associated_With_Disease&apos; some &apos;Chronic Myelogenous Leukemia, BCR-ABL1 Positive&apos;) and (&apos;Gene_In_Chromosomal_Location&apos; some &apos;9q34.1&apos;) and (&apos;Gene_Found_In_Organism&apos; some &apos;Human&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17325</classIRI>
<classLabel>Serine/Threonine Protein Kinase</classLabel>
<deletedAxiom>&apos;Serine/Threonine Protein Kinase&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Protein Phosphorylation Process&apos;</deletedAxiom>
<newAxiom>&apos;Serine/Threonine Protein Kinase&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Serine/Threonine Phosphorylation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131424</classIRI>
<classLabel>Congenital Generalized Lipodystrophy</classLabel>
<deletedAxiom>&apos;Congenital Generalized Lipodystrophy&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Congenital Generalized Lipodystrophy&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131004</classIRI>
<classLabel>Sotos Syndrome</classLabel>
<deletedAxiom>&apos;Sotos Syndrome&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Sotos Syndrome&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131011</classIRI>
<classLabel>Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation Syndrome</classLabel>
<deletedAxiom>&apos;Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation Syndrome&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation Syndrome&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4613</classIRI>
<classLabel>Benign Exocrine Pancreas Neoplasm</classLabel>
<deletedAxiom>&apos;Benign Exocrine Pancreas Neoplasm&apos; EquivalentTo &apos;Pancreatic Exocrine Neoplasm&apos; and &apos;Benign Pancreatic Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Exocrine Pancreas&apos;)</deletedAxiom>
<newAxiom>&apos;Benign Exocrine Pancreas Neoplasm&apos; EquivalentTo &apos;Pancreatic Exocrine Neoplasm&apos; and &apos;Benign Pancreatic Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4456</classIRI>
<classLabel>Malignant Mesothelioma</classLabel>
<deletedAxiom>&apos;Malignant Mesothelioma&apos; EquivalentTo &apos;Mesothelioma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Mesothelial Cell&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CDKN2A Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Malignant Mesothelioma&apos; EquivalentTo &apos;Mesothelioma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Mesothelial Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4997</classIRI>
<classLabel>Refractory Nodal Marginal Zone Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory Nodal Marginal Zone Lymphoma&apos; EquivalentTo &apos;Refractory Mature B-Cell Non-Hodgkin Lymphoma&apos; and &apos;Nodal Marginal Zone Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Nodal Marginal Zone Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143085 and &apos;Nodal Marginal Zone Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4731</classIRI>
<classLabel>Neuropathy</classLabel>
<deletedAxiom>&apos;Neuropathy&apos; SubClassOf &apos;Peripheral Nervous System Disorder&apos;</deletedAxiom>
<newAxiom>&apos;Neuropathy&apos; SubClassOf &apos;Nervous System Disorder&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112007</classIRI>
<classLabel>Masaoka Stage I</classLabel>
<deletedAxiom>&apos;Masaoka Stage I&apos; SubClassOf &apos;Masaoka Staging System&apos;</deletedAxiom>
<newAxiom>&apos;Masaoka Stage I&apos; EquivalentTo &apos;Masaoka Staging System&apos; and (&apos;Disease_Is_Stage&apos; some &apos;Stage I&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112006</classIRI>
<classLabel>Masaoka Staging System</classLabel>
<deletedAxiom>&apos;Masaoka Staging System&apos; SubClassOf &apos;Staging System&apos;</deletedAxiom>
<newAxiom>&apos;Masaoka Staging System&apos; EquivalentTo &apos;Thymoma&apos; and (&apos;Disease_Is_Stage&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143151)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112009</classIRI>
<classLabel>Masaoka Stage IIb</classLabel>
<deletedAxiom>&apos;Masaoka Stage IIb&apos; SubClassOf &apos;Masaoka Stage II&apos;</deletedAxiom>
<newAxiom>&apos;Masaoka Stage IIb&apos; EquivalentTo &apos;Masaoka Stage II&apos; and (&apos;Disease_Is_Stage&apos; some &apos;Stage IIB&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112008</classIRI>
<classLabel>Masaoka Stage IIa</classLabel>
<deletedAxiom>&apos;Masaoka Stage IIa&apos; SubClassOf &apos;Masaoka Stage II&apos;</deletedAxiom>
<newAxiom>&apos;Masaoka Stage IIa&apos; EquivalentTo &apos;Masaoka Stage II&apos; and (&apos;Disease_Is_Stage&apos; some &apos;Stage IIA&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112010</classIRI>
<classLabel>Masaoka Stage III</classLabel>
<deletedAxiom>&apos;Masaoka Stage III&apos; SubClassOf &apos;Masaoka Staging System&apos;</deletedAxiom>
<newAxiom>&apos;Masaoka Stage III&apos; EquivalentTo &apos;Masaoka Staging System&apos; and (&apos;Disease_Is_Stage&apos; some &apos;Stage III&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112012</classIRI>
<classLabel>Masaoka Stage IVb</classLabel>
<deletedAxiom>&apos;Masaoka Stage IVb&apos; SubClassOf &apos;Masaoka Stage IV&apos;</deletedAxiom>
<newAxiom>&apos;Masaoka Stage IVb&apos; EquivalentTo &apos;Masaoka Stage IV&apos; and (&apos;Disease_Is_Stage&apos; some &apos;Stage IVB&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112011</classIRI>
<classLabel>Masaoka Stage IVa</classLabel>
<deletedAxiom>&apos;Masaoka Stage IVa&apos; SubClassOf &apos;Masaoka Stage IV&apos;</deletedAxiom>
<newAxiom>&apos;Masaoka Stage IVa&apos; EquivalentTo &apos;Masaoka Stage IV&apos; and (&apos;Disease_Is_Stage&apos; some &apos;Stage IVA&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126659</classIRI>
<classLabel>NCIt Neoplasm Core Terminology</classLabel>
<deletedAxiom>&apos;NCIt Neoplasm Core Terminology&apos; SubClassOf &apos;Terminology Subset&apos;</deletedAxiom>
<newAxiom>&apos;NCIt Neoplasm Core Terminology&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143048</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82261</classIRI>
<classLabel>Povidone K29/32</classLabel>
<deletedAxiom>&apos;Povidone K29/32&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Povidone K29/32&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126345</classIRI>
<classLabel>STAT3 Gain of Function</classLabel>
<deletedAxiom>&apos;STAT3 Gain of Function&apos; SubClassOf &apos;Gene Abnormality&apos;</deletedAxiom>
<newAxiom>&apos;STAT3 Gain of Function&apos; SubClassOf &apos;STAT Family Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126346</classIRI>
<classLabel>STAT1 Gain of Function</classLabel>
<deletedAxiom>&apos;STAT1 Gain of Function&apos; SubClassOf &apos;Gene Abnormality&apos;</deletedAxiom>
<newAxiom>&apos;STAT1 Gain of Function&apos; SubClassOf &apos;STAT Family Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18053</classIRI>
<classLabel>LY-49</classLabel>
<deletedAxiom>&apos;LY-49&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;LY-49&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18249</classIRI>
<classLabel>CDH1 Gene</classLabel>
<newAxiom>&apos;CDH1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Calcium Binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18322</classIRI>
<classLabel>EWSR1 Gene</classLabel>
<deletedAxiom>&apos;EWSR1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Desmoplastic Small Round Cell Tumor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18334</classIRI>
<classLabel>Oncogene LCK</classLabel>
<deletedAxiom>&apos;Oncogene LCK&apos; EquivalentTo &apos;Oncogenes, Tyrosine-Kinase&apos; and (&apos;Allele_In_Chromosomal_Location&apos; some &apos;1p35-p34.3&apos;) and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Found_In_Organism&apos; some &apos;Human&apos;)</deletedAxiom>
<newAxiom>&apos;Oncogene LCK&apos; EquivalentTo &apos;SRC Family Oncogene&apos; and (&apos;Allele_In_Chromosomal_Location&apos; some &apos;1p35-p34.3&apos;) and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Found_In_Organism&apos; some &apos;Human&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18333</classIRI>
<classLabel>Oncogene FGR</classLabel>
<deletedAxiom>&apos;Oncogene FGR&apos; EquivalentTo &apos;Oncogenes, Tyrosine-Kinase&apos; and (&apos;Allele_In_Chromosomal_Location&apos; some &apos;1p36.2-p36.1&apos;) and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Tyrosine Phosphorylation&apos;) and (&apos;Gene_Found_In_Organism&apos; some &apos;Human&apos;)</deletedAxiom>
<newAxiom>&apos;Oncogene FGR&apos; EquivalentTo &apos;SRC Family Oncogene&apos; and (&apos;Allele_In_Chromosomal_Location&apos; some &apos;1p36.2-p36.1&apos;) and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Tyrosine Phosphorylation&apos;) and (&apos;Gene_Found_In_Organism&apos; some &apos;Human&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18349</classIRI>
<classLabel>Oncogene YES-1</classLabel>
<deletedAxiom>&apos;Oncogene YES-1&apos; EquivalentTo &apos;Oncogenes, Protein-Kinase&apos; and (&apos;Allele_In_Chromosomal_Location&apos; some &apos;18p11.31-p11.21&apos;) and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Found_In_Organism&apos; some &apos;Human&apos;)</deletedAxiom>
<newAxiom>&apos;Oncogene YES-1&apos; EquivalentTo &apos;SRC Family Oncogene&apos; and (&apos;Allele_In_Chromosomal_Location&apos; some &apos;18p11.31-p11.21&apos;) and (&apos;Gene_Plays_Role_In_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Found_In_Organism&apos; some &apos;Human&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5096</classIRI>
<classLabel>Refractory Splenic Marginal Zone Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory Splenic Marginal Zone Lymphoma&apos; EquivalentTo &apos;Splenic Marginal Zone Lymphoma&apos; and &apos;Refractory Mature B-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Splenic Marginal Zone Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143085 and &apos;Splenic Marginal Zone Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5090</classIRI>
<classLabel>Refractory Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue</classLabel>
<deletedAxiom>&apos;Refractory Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue&apos; EquivalentTo &apos;Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue&apos; and &apos;Refractory Mature B-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143085 and &apos;Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131858</classIRI>
<classLabel>Hypogonadotropic Hypogonadism with Anosmia</classLabel>
<deletedAxiom>&apos;Hypogonadotropic Hypogonadism with Anosmia&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Hypogonadotropic Hypogonadism with Anosmia&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18563</classIRI>
<classLabel>WT2 Protein</classLabel>
<deletedAxiom>&apos;WT2 Protein&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;WT2 Protein&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77157</classIRI>
<classLabel>CDH2 Gene</classLabel>
<deletedAxiom>&apos;CDH2 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Cell Adhesion Process&apos;</deletedAxiom>
<newAxiom>&apos;CDH2 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Calcium Binding&apos;</newAxiom>
<newAxiom>&apos;CDH2 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Cell-Cell Adhesion Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129264</classIRI>
<classLabel>IDH Gene Family Mutation</classLabel>
<deletedAxiom>&apos;IDH Gene Family Mutation&apos; SubClassOf &apos;Gene Mutant&apos;</deletedAxiom>
<newAxiom>&apos;IDH Gene Family Mutation&apos; SubClassOf &apos;Gene Abnormality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7805</classIRI>
<classLabel>Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma</classLabel>
<deletedAxiom>&apos;Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma&apos; EquivalentTo &apos;Recurrent Primary Malignant Neoplasm&apos; and &apos;Primary Cutaneous T-Cell Non-Hodgkin Lymphoma&apos; and &apos;Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142876 and &apos;Primary Cutaneous T-Cell Non-Hodgkin Lymphoma&apos; and &apos;Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C134948</classIRI>
<classLabel>Mouse Thyroid Gland Parafollicular Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Mouse Thyroid Gland Parafollicular Cell Carcinoma&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Mouse Thyroid Gland Parafollicular Cell Carcinoma&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120368</classIRI>
<classLabel>Central Hypogonadism</classLabel>
<deletedAxiom>&apos;Central Hypogonadism&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Central Hypogonadism&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C134531</classIRI>
<classLabel>Hamster Experimental Organism Diagnosis</classLabel>
<deletedAxiom>&apos;Hamster Experimental Organism Diagnosis&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Hamster Experimental Organism Diagnosis&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63494</classIRI>
<classLabel>Hematopoietic Stem Cell Mobilization</classLabel>
<deletedAxiom>&apos;Hematopoietic Stem Cell Mobilization&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Hematopoietic Stem Cell Mobilization&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120031</classIRI>
<classLabel>CTX</classLabel>
<newAxiom>&apos;CTX&apos; SubClassOf &apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Type I Collagen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38642</classIRI>
<classLabel>Lymphoblasts 25 Percent or Less of Bone Marrow Nucleated Cells</classLabel>
<deletedAxiom>&apos;Lymphoblasts 25 Percent or Less of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blast Cells Increased in Bone Marrow&apos;</deletedAxiom>
<newAxiom>&apos;Lymphoblasts 25 Percent or Less of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blasts Under 30 Percent of Bone Marrow Nucleated Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97427</classIRI>
<classLabel>CDH11 Gene</classLabel>
<newAxiom>&apos;CDH11 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Calcium Binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97613</classIRI>
<classLabel>C12orf9 Gene</classLabel>
<deletedAxiom>&apos;C12orf9 Gene&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;C12orf9 Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97614</classIRI>
<classLabel>C12orf9 wt Allele</classLabel>
<deletedAxiom>&apos;C12orf9 wt Allele&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;C12orf9 wt Allele&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101753</classIRI>
<classLabel>CDH23 Gene</classLabel>
<newAxiom>&apos;CDH23 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Calcium Binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C24736</classIRI>
<classLabel>RGS19 Gene</classLabel>
<deletedAxiom>&apos;RGS19 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Signal Transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C24737</classIRI>
<classLabel>RGS2 Gene</classLabel>
<deletedAxiom>&apos;RGS2 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Signal Transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C24735</classIRI>
<classLabel>RGS1 Gene</classLabel>
<deletedAxiom>&apos;RGS1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Signal Transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C24738</classIRI>
<classLabel>RGS3 Gene</classLabel>
<deletedAxiom>&apos;RGS3 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Signal Transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C24844</classIRI>
<classLabel>WWTR1 Gene</classLabel>
<deletedAxiom>&apos;WWTR1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Epithelioid Hemangioendothelioma&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101440</classIRI>
<classLabel>CAMTA1 Gene</classLabel>
<deletedAxiom>&apos;CAMTA1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Epithelioid Hemangioendothelioma&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C140955</classIRI>
<classLabel>Somewhat Disagree</classLabel>
<deletedAxiom>&apos;Somewhat Disagree&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Somewhat Disagree&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C140956</classIRI>
<classLabel>Somewhat Agree</classLabel>
<deletedAxiom>&apos;Somewhat Agree&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Somewhat Agree&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115313</classIRI>
<classLabel>CDH4 Gene</classLabel>
<newAxiom>&apos;CDH4 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Calcium Binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8562</classIRI>
<classLabel>Ocular Melanoma</classLabel>
<deletedAxiom>&apos;Ocular Melanoma&apos; EquivalentTo &apos;Malignant Eye Neoplasm&apos; and &apos;Non-Cutaneous Melanoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Eye&apos;)</deletedAxiom>
<newAxiom>&apos;Ocular Melanoma&apos; EquivalentTo &apos;Melanoma&apos; and &apos;Malignant Eye Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Eye&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8420</classIRI>
<classLabel>Diffuse Malignant Mesothelioma</classLabel>
<deletedAxiom>&apos;Diffuse Malignant Mesothelioma&apos; EquivalentTo &apos;Malignant Mesothelioma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Diffuse Pattern&apos;)</deletedAxiom>
<newAxiom>&apos;Diffuse Malignant Mesothelioma&apos; EquivalentTo &apos;Malignant Mesothelioma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Diffuse Pattern&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 1q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 17q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 5p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 13q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 1p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 3p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 22q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 7p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 6q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 9p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 4q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 14q&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;BAP1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NF2 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CDKN2A Gene Inactivation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129719</classIRI>
<classLabel>47,XYY Syndrome</classLabel>
<deletedAxiom>&apos;47,XYY Syndrome&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;47,XYY Syndrome&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129743</classIRI>
<classLabel>Hepatocyte Nuclear Factor 1-Beta-Associated Monogenic Diabetes</classLabel>
<deletedAxiom>&apos;Hepatocyte Nuclear Factor 1-Beta-Associated Monogenic Diabetes&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Hepatocyte Nuclear Factor 1-Beta-Associated Monogenic Diabetes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8300</classIRI>
<classLabel>Desmoplastic Small Round Cell Tumor</classLabel>
<deletedAxiom>&apos;Desmoplastic Small Round Cell Tumor&apos; EquivalentTo &apos;Small Cell Sarcoma&apos; and &apos;Malignant Soft Tissue Tumor of Uncertain Differentiation&apos; and &apos;Soft Tissue Sarcoma&apos; and ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(11;22)(p13;q12)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-WT1 Fusion Protein Expression&apos;)) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Small Round Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Desmoplastic Stroma Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Ascites&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Mass&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tumor Cell Necrosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;High Mitotic Activity&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/WT1 Fusion Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Desmoplastic Small Round Cell Tumor&apos; EquivalentTo &apos;Small Cell Sarcoma&apos; and &apos;Malignant Soft Tissue Tumor of Uncertain Differentiation&apos; and &apos;Soft Tissue Sarcoma&apos; and ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(11;22)(p13;q12)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-WT1 Fusion Protein Expression&apos;)) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Small Round Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Desmoplastic Stroma Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Ascites&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Mass&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tumor Cell Necrosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;High Mitotic Activity&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/WT1 Fusion Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129521</classIRI>
<classLabel>Past Seven Days How Much Headache Interfered with Usual or Daily Activities</classLabel>
<deletedAxiom>&apos;Past Seven Days How Much Headache Interfered with Usual or Daily Activities&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Past Seven Days How Much Headache Interfered with Usual or Daily Activities&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129514</classIRI>
<classLabel>Worst Severity Past Seven Days Hand-Foot Syndrome</classLabel>
<deletedAxiom>&apos;Worst Severity Past Seven Days Hand-Foot Syndrome&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Worst Severity Past Seven Days Hand-Foot Syndrome&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8938</classIRI>
<classLabel>Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma&apos; EquivalentTo &apos;Primary Cutaneous T-Cell Non-Hodgkin Lymphoma&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142877 and &apos;Primary Cutaneous T-Cell Non-Hodgkin Lymphoma&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115034</classIRI>
<classLabel>Masaoka Stage IV</classLabel>
<deletedAxiom>&apos;Masaoka Stage IV&apos; SubClassOf &apos;Masaoka Staging System&apos;</deletedAxiom>
<newAxiom>&apos;Masaoka Stage IV&apos; EquivalentTo &apos;Masaoka Staging System&apos; and (&apos;Disease_Is_Stage&apos; some &apos;Stage IV&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115033</classIRI>
<classLabel>Masaoka Stage II</classLabel>
<deletedAxiom>&apos;Masaoka Stage II&apos; SubClassOf &apos;Masaoka Staging System&apos;</deletedAxiom>
<newAxiom>&apos;Masaoka Stage II&apos; EquivalentTo &apos;Masaoka Staging System&apos; and (&apos;Disease_Is_Stage&apos; some &apos;Stage II&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115012</classIRI>
<classLabel>CAAX Prenyl Protease 2</classLabel>
<deletedAxiom>&apos;CAAX Prenyl Protease 2&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Protein Cleavage&apos;</deletedAxiom>
<deletedAxiom>&apos;CAAX Prenyl Protease 2&apos; SubClassOf &apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Terpenoid Biosynthesis Pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;CAAX Prenyl Protease 2&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RCE1 Gene&apos;</deletedAxiom>
<deletedAxiom>&apos;CAAX Prenyl Protease 2&apos; SubClassOf &apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Rough Endoplasmic Reticulum&apos;</deletedAxiom>
<deletedAxiom>&apos;CAAX Prenyl Protease 2&apos; SubClassOf &apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;</deletedAxiom>
<deletedAxiom>&apos;CAAX Prenyl Protease 2&apos; SubClassOf &apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;</deletedAxiom>
<deletedAxiom>&apos;CAAX Prenyl Protease 2&apos; SubClassOf &apos;Metallopeptidase&apos;</deletedAxiom>
<deletedAxiom>&apos;CAAX Prenyl Protease 2&apos; SubClassOf &apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Smooth Endoplasmic Reticulum&apos;</deletedAxiom>
<newAxiom>&apos;CAAX Prenyl Protease 2&apos; EquivalentTo &apos;Metallopeptidase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Terpenoid Biosynthesis Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Rough Endoplasmic Reticulum&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Smooth Endoplasmic Reticulum&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Protein Cleavage&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RCE1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19900</classIRI>
<classLabel>Proteolytic Processing</classLabel>
<deletedAxiom>&apos;Proteolytic Processing&apos; SubClassOf &apos;Protein Metabolism Process&apos;</deletedAxiom>
<newAxiom>&apos;Proteolytic Processing&apos; SubClassOf &apos;Post-Translational Modification&apos;</newAxiom>
<newAxiom>&apos;Proteolytic Processing&apos; SubClassOf &apos;Proteolysis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129495</classIRI>
<classLabel>Degree Fatigue Interfered with Physical Functioning</classLabel>
<deletedAxiom>&apos;Degree Fatigue Interfered with Physical Functioning&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Degree Fatigue Interfered with Physical Functioning&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133888</classIRI>
<classLabel>Canine Neoplasm</classLabel>
<deletedAxiom>&apos;Canine Neoplasm&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Canine Neoplasm&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133861</classIRI>
<classLabel>SPL PQ/CMC Source Organism Country of Origin Terminology</classLabel>
<deletedAxiom>&apos;SPL PQ/CMC Source Organism Country of Origin Terminology&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;SPL PQ/CMC Source Organism Country of Origin Terminology&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133854</classIRI>
<classLabel>SPL PQ/CMC Dosage Form Terminology</classLabel>
<deletedAxiom>&apos;SPL PQ/CMC Dosage Form Terminology&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;SPL PQ/CMC Dosage Form Terminology&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133806</classIRI>
<classLabel>SPL PQ/CMC Physicochemical Properties Terminology</classLabel>
<deletedAxiom>&apos;SPL PQ/CMC Physicochemical Properties Terminology&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;SPL PQ/CMC Physicochemical Properties Terminology&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133676</classIRI>
<classLabel>RAF1 Gene Mutation</classLabel>
<newAxiom>&apos;RAF1 Gene Mutation&apos; SubClassOf &apos;RAF Family Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133515</classIRI>
<classLabel>Medical Device Dislodged or Dislocated</classLabel>
<deletedAxiom>&apos;Medical Device Dislodged or Dislocated&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Medical Device Dislodged or Dislocated&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133506</classIRI>
<classLabel>Peeled/Delaminated Medical Device</classLabel>
<deletedAxiom>&apos;Peeled/Delaminated Medical Device&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Peeled/Delaminated Medical Device&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Medical Device Material Twisted/Bent</classLabel>
<deletedAxiom>&apos;Medical Device Material Twisted/Bent&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Medical Device Material Twisted/Bent&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Primary Effusion Lymphoma</classLabel>
<deletedAxiom>&apos;Primary Effusion Lymphoma&apos; EquivalentTo &apos;HHV8-Related Malignant Neoplasm&apos; and &apos;Virus-Related Lymphoma&apos; and &apos;Diffuse Large B-Cell Lymphoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Body Cavity&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Postgerminal Center B-Lymphocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic B-Immunoblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Plasmablastic Immunoblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Anaplastic Large B-Lymphocyte&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 12&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome X&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pericardial Effusion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pleural Effusion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Peritoneal Effusion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Kaposi Sarcoma&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gene Rearrangement&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Effusion Lymphoma&apos; EquivalentTo &apos;HHV8-Related Malignant Neoplasm&apos; and &apos;Virus-Related Lymphoma&apos; and &apos;Diffuse Large B-Cell Lymphoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Body Cavity&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Postgerminal Center B-Lymphocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic B-Immunoblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Plasmablastic Immunoblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Anaplastic Large B-Lymphocyte&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Trisomy 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Trisomy 12&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 12&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Trisomy 7&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome X&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pericardial Effusion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pleural Effusion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Peritoneal Effusion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Kaposi Sarcoma&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gene Rearrangement&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133246</classIRI>
<classLabel>SPL Tissue Form Terminology</classLabel>
<deletedAxiom>&apos;SPL Tissue Form Terminology&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;SPL Tissue Form Terminology&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133244</classIRI>
<classLabel>SPL Blood Form Terminology</classLabel>
<deletedAxiom>&apos;SPL Blood Form Terminology&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;SPL Blood Form Terminology&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133157</classIRI>
<classLabel>Stage 0 Laryngeal Cancer AJCC v8</classLabel>
<deletedAxiom>&apos;Stage 0 Laryngeal Cancer AJCC v8&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Stage 0 Laryngeal Cancer AJCC v8&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98131</classIRI>
<classLabel>Hypofibrinogenemia</classLabel>
<deletedAxiom>&apos;Hypofibrinogenemia&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Hypofibrinogenemia&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133004</classIRI>
<classLabel>Stage 0 Hypopharyngeal Carcinoma AJCC v8</classLabel>
<deletedAxiom>&apos;Stage 0 Hypopharyngeal Carcinoma AJCC v8&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Stage 0 Hypopharyngeal Carcinoma AJCC v8&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133075</classIRI>
<classLabel>Stage 0 Nasal Cavity and Paranasal Sinus Cancer AJCC v8</classLabel>
<deletedAxiom>&apos;Stage 0 Nasal Cavity and Paranasal Sinus Cancer AJCC v8&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Stage 0 Nasal Cavity and Paranasal Sinus Cancer AJCC v8&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25580</classIRI>
<classLabel>N Stage</classLabel>
<deletedAxiom>&apos;N Stage&apos; SubClassOf &apos;Disease Stage Qualifier&apos;</deletedAxiom>
<newAxiom>&apos;N Stage&apos; SubClassOf &apos;Classification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25727</classIRI>
<classLabel>M Stage</classLabel>
<deletedAxiom>&apos;M Stage&apos; SubClassOf &apos;Disease Stage Qualifier&apos;</deletedAxiom>
<newAxiom>&apos;M Stage&apos; SubClassOf &apos;Classification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25728</classIRI>
<classLabel>T Stage</classLabel>
<deletedAxiom>&apos;T Stage&apos; SubClassOf &apos;Disease Stage Qualifier&apos;</deletedAxiom>
<newAxiom>&apos;T Stage&apos; SubClassOf &apos;Classification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C50832</classIRI>
<classLabel>Incompatible Blood Transfusion</classLabel>
<deletedAxiom>&apos;Incompatible Blood Transfusion&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Incompatible Blood Transfusion&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C50898</classIRI>
<classLabel>NOS2C wt Allele</classLabel>
<deletedAxiom>&apos;NOS2C wt Allele&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;NOS2C wt Allele&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C50897</classIRI>
<classLabel>NOS2B wt Allele</classLabel>
<deletedAxiom>&apos;NOS2B wt Allele&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;NOS2B wt Allele&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84672</classIRI>
<classLabel>Dihydropyrimidine Dehydrogenase Deficiency</classLabel>
<newAxiom>&apos;Dihydropyrimidine Dehydrogenase Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;DPYD Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128821</classIRI>
<classLabel>MSH2 Gene Mutation</classLabel>
<newAxiom>&apos;MSH2 Gene Mutation&apos; SubClassOf &apos;Mismatch Repair Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128822</classIRI>
<classLabel>PMS1 Gene Mutation</classLabel>
<newAxiom>&apos;PMS1 Gene Mutation&apos; SubClassOf &apos;Mismatch Repair Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45403</classIRI>
<classLabel>NOTCH1 Gene Mutation</classLabel>
<newAxiom>&apos;NOTCH1 Gene Mutation&apos; SubClassOf &apos;NOTCH Family Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45511</classIRI>
<classLabel>Lung Mucinous Cystadenocarcinoma</classLabel>
<deletedAxiom>&apos;Lung Mucinous Cystadenocarcinoma&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Lung Mucinous Cystadenocarcinoma&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45587</classIRI>
<classLabel>Germline Mutation Abnormality</classLabel>
<deletedAxiom>&apos;Germline Mutation Abnormality&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Germline Mutation Abnormality&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784</classIRI>
<classLabel>NCIt Antineoplastic Agent Terminology</classLabel>
<deletedAxiom>&apos;NCIt Antineoplastic Agent Terminology&apos; SubClassOf &apos;Terminology Subset&apos;</deletedAxiom>
<newAxiom>&apos;NCIt Antineoplastic Agent Terminology&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143048</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45934</classIRI>
<classLabel>HRAS Gene Mutation</classLabel>
<newAxiom>&apos;HRAS Gene Mutation&apos; SubClassOf &apos;RAS Family Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128293</classIRI>
<classLabel>Broccoli Sprout/Broccoli Seed Extract Supplement</classLabel>
<deletedAxiom>&apos;Broccoli Sprout/Broccoli Seed Extract Supplement&apos; SubClassOf &apos;Dietary Supplement&apos;</deletedAxiom>
<newAxiom>&apos;Broccoli Sprout/Broccoli Seed Extract Supplement&apos; SubClassOf &apos;Antioxidant&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142113</classIRI>
<classLabel>Blasts 10 Percent or Less of Bone Marrow Nucleated Cells</classLabel>
<deletedAxiom>&apos;Blasts 10 Percent or Less of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blasts Under 20 Percent of Bone Marrow Nucleated Cells&apos;</deletedAxiom>
<newAxiom>&apos;Blasts 10 Percent or Less of Bone Marrow Nucleated Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143153</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90511</classIRI>
<classLabel>Liver Cancer by AJCC v6 Stage</classLabel>
<deletedAxiom>&apos;Liver Cancer by AJCC v6 Stage&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Liver Cancer by AJCC v6 Stage&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26048</classIRI>
<classLabel>RGS Family Gene</classLabel>
<newAxiom>&apos;RGS Family Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;G Protein-Coupled Receptor Signaling&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26114</classIRI>
<classLabel>Cell Surface Extension</classLabel>
<deletedAxiom>&apos;Cell Surface Extension&apos; SubClassOf &apos;Cell Movement Process&apos;</deletedAxiom>
<newAxiom>&apos;Cell Surface Extension&apos; SubClassOf &apos;Cell Membrane Process&apos;</newAxiom>
<newAxiom>&apos;Cell Surface Extension&apos; SubClassOf &apos;Biological_Process_Is_Part_Of_Process&apos; some &apos;Cell Movement Process&apos;</newAxiom>
<newAxiom>&apos;Cell Surface Extension&apos; SubClassOf &apos;Biological_Process_Is_Part_Of_Process&apos; some &apos;Regulation of Cell Shape&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26300</classIRI>
<classLabel>Hepatocellular Carcinoma Protein HHCM</classLabel>
<deletedAxiom>&apos;Hepatocellular Carcinoma Protein HHCM&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Hepatocellular Carcinoma Protein HHCM&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99461</classIRI>
<classLabel>Paclitaxel Trevatide</classLabel>
<deletedAxiom>&apos;Paclitaxel Trevatide&apos; SubClassOf &apos;Immunoconjugate&apos;</deletedAxiom>
<newAxiom>&apos;Paclitaxel Trevatide&apos; SubClassOf &apos;Paclitaxel Preparation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C51557</classIRI>
<classLabel>KLRA1 wt Allele</classLabel>
<deletedAxiom>&apos;KLRA1 wt Allele&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;KLRA1 wt Allele&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136970</classIRI>
<classLabel>Deleterious EPCAM Gene Mutation</classLabel>
<newAxiom>&apos;Deleterious EPCAM Gene Mutation&apos; SubClassOf &apos;EPCAM Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1921</classIRI>
<classLabel>Prothymosin L</classLabel>
<deletedAxiom>&apos;Prothymosin L&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Prothymosin L&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137701</classIRI>
<classLabel>Blasts Under 25 Percent of Bone Marrow Nucleated Cells</classLabel>
<deletedAxiom>&apos;Blasts Under 25 Percent of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blast Cells Increased in Bone Marrow&apos;</deletedAxiom>
<newAxiom>&apos;Blasts Under 25 Percent of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blasts Under 30 Percent of Bone Marrow Nucleated Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137703</classIRI>
<classLabel>Blasts 5-10 Percent of Bone Marrow Nucleated Cells</classLabel>
<deletedAxiom>&apos;Blasts 5-10 Percent of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blasts Under 20 Percent of Bone Marrow Nucleated Cells&apos;</deletedAxiom>
<newAxiom>&apos;Blasts 5-10 Percent of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blasts 10 Percent or Less of Bone Marrow Nucleated Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137695</classIRI>
<classLabel>Blasts 20 Percent or Less of Bone Marrow Nucleated Cells</classLabel>
<deletedAxiom>&apos;Blasts 20 Percent or Less of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blast Cells Increased in Bone Marrow&apos;</deletedAxiom>
<newAxiom>&apos;Blasts 20 Percent or Less of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blasts Under 25 Percent of Bone Marrow Nucleated Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137694</classIRI>
<classLabel>Myeloblasts 10 Percent or More of Bone Marrow Nucleated Cells</classLabel>
<newAxiom>&apos;Myeloblasts 10 Percent or More of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Immature Myeloid Cells Increased in Bone Marrow&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C71269</classIRI>
<classLabel>HLA-Bw4 Antigen</classLabel>
<newAxiom>&apos;HLA-Bw4 Antigen&apos; SubClassOf (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;HLA-A Gene&apos;) or (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;HLA-B Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142776</classIRI>
<classLabel>Tumor Necrosis Factor Ligand Superfamily Member 18</classLabel>
<deletedAxiom>&apos;Tumor Necrosis Factor Ligand Superfamily Member 18&apos; SubClassOf &apos;Tumor Necrosis Factor Family Protein&apos;</deletedAxiom>
<newAxiom>&apos;Tumor Necrosis Factor Ligand Superfamily Member 18&apos; EquivalentTo &apos;Tumor Necrosis Factor Family Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cytokine-Cytokine Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Endothelial Cell&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;T-Cell Activation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;T-Cell Proliferation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Chemotaxis Induction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Leukocyte Trafficking Induction&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143026)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116937</classIRI>
<classLabel>Carbohydrate Sulfotransferase 3</classLabel>
<deletedAxiom>&apos;Carbohydrate Sulfotransferase 3&apos; EquivalentTo &apos;Transferase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Glycosaminoglycan Biosynthesis Pathway - Chondroitin Sulfate&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Golgi Apparatus&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Sulfotransferase&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Carbohydrate Metabolic Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Protein Metabolism Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CHST3 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Carbohydrate Sulfotransferase 3&apos; EquivalentTo &apos;Transferase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Glycosaminoglycan Biosynthesis Pathway - Chondroitin Sulfate&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Golgi Apparatus&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Sulfotransferase&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Biosynthetic Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Carbohydrate Metabolic Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Protein Metabolism Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CHST3 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116934</classIRI>
<classLabel>CHST3 Gene</classLabel>
<newAxiom>&apos;CHST3 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Biosynthetic Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116963</classIRI>
<classLabel>Procollagen Type I N-Terminal Peptide</classLabel>
<newAxiom>&apos;Procollagen Type I N-Terminal Peptide&apos; SubClassOf &apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Type I Collagen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C33886</classIRI>
<classLabel>Vocalis Muscle</classLabel>
<deletedAxiom>&apos;Vocalis Muscle&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Vocalis Muscle&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C141293</classIRI>
<classLabel>Pancreatic Fluid</classLabel>
<deletedAxiom>&apos;Pancreatic Fluid&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Pancreatic Fluid&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C141297</classIRI>
<classLabel>Blasts 30 Percent or Less of Bone Marrow Nucleated Cells</classLabel>
<deletedAxiom>&apos;Blasts 30 Percent or Less of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blast Cells Increased in Bone Marrow&apos;</deletedAxiom>
<newAxiom>&apos;Blasts 30 Percent or Less of Bone Marrow Nucleated Cells&apos; SubClassOf &apos;Blasts 50 Percent or Less of Bone Marrow Nucleated Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C92485</classIRI>
<classLabel>Liver Cancer by AJCC v7 Stage</classLabel>
<deletedAxiom>&apos;Liver Cancer by AJCC v7 Stage&apos; SubClassOf &apos;Retired Concept Current Year&apos;</deletedAxiom>
<newAxiom>&apos;Liver Cancer by AJCC v7 Stage&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116020</classIRI>
<classLabel>Procollagen Type I C-Terminal Peptide</classLabel>
<newAxiom>&apos;Procollagen Type I C-Terminal Peptide&apos; SubClassOf &apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Type I Collagen&apos;</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143206</classIRI>
<classLabel>Bacteremia, CTCAE</classLabel>
<newAxiom>'Bacteremia, CTCAE' SubClassOf 'Infections and Infestations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143207</classIRI>
<classLabel>Cytomegalovirus Infection Reactivation, CTCAE</classLabel>
<newAxiom>'Cytomegalovirus Infection Reactivation, CTCAE' SubClassOf 'Infections and Infestations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143208</classIRI>
<classLabel>Epstein-Barr Virus Infection Reactivation, CTCAE</classLabel>
<newAxiom>'Epstein-Barr Virus Infection Reactivation, CTCAE' SubClassOf 'Infections and Infestations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143209</classIRI>
<classLabel>Folliculitis, CTCAE</classLabel>
<newAxiom>'Folliculitis, CTCAE' SubClassOf 'Infections and Infestations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143200</classIRI>
<classLabel>Rectal Fissure, CTCAE</classLabel>
<newAxiom>'Rectal Fissure, CTCAE' SubClassOf 'Gastrointestinal Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143201</classIRI>
<classLabel>Disease Progression, CTCAE</classLabel>
<newAxiom>'Disease Progression, CTCAE' SubClassOf 'General Disorders and Administration Site Conditions, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143202</classIRI>
<classLabel>Generalized Edema, CTCAE</classLabel>
<newAxiom>'Generalized Edema, CTCAE' SubClassOf 'General Disorders and Administration Site Conditions, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143203</classIRI>
<classLabel>Vaccination Site Lymphadenopathy, CTCAE</classLabel>
<newAxiom>'Vaccination Site Lymphadenopathy, CTCAE' SubClassOf 'General Disorders and Administration Site Conditions, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143204</classIRI>
<classLabel>Budd-Chiari Syndrome, CTCAE</classLabel>
<newAxiom>'Budd-Chiari Syndrome, CTCAE' SubClassOf 'Hepatobiliary Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143205</classIRI>
<classLabel>Sinusoidal Obstruction Syndrome, CTCAE</classLabel>
<newAxiom>'Sinusoidal Obstruction Syndrome, CTCAE' SubClassOf 'Hepatobiliary Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143230</classIRI>
<classLabel>Anosmia, CTCAE</classLabel>
<newAxiom>'Anosmia, CTCAE' SubClassOf 'Nervous System Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143228</classIRI>
<classLabel>Skin Papilloma, CTCAE</classLabel>
<newAxiom>'Skin Papilloma, CTCAE' SubClassOf 'Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps), CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143229</classIRI>
<classLabel>Tumor Hemorrhage, CTCAE</classLabel>
<newAxiom>'Tumor Hemorrhage, CTCAE' SubClassOf 'Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps), CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143220</classIRI>
<classLabel>Thyroid Stimulating Hormone Increased, CTCAE</classLabel>
<newAxiom>'Thyroid Stimulating Hormone Increased, CTCAE' SubClassOf 'Investigations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143221</classIRI>
<classLabel>Hyperlipidemia, CTCAE</classLabel>
<newAxiom>'Hyperlipidemia, CTCAE' SubClassOf 'Metabolism and Nutrition Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143222</classIRI>
<classLabel>Hyperphosphatemia, CTCAE</classLabel>
<newAxiom>'Hyperphosphatemia, CTCAE' SubClassOf 'Metabolism and Nutrition Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143223</classIRI>
<classLabel>Chest Wall Necrosis, CTCAE</classLabel>
<newAxiom>'Chest Wall Necrosis, CTCAE' SubClassOf 'Musculoskeletal and Connective Tissue Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143224</classIRI>
<classLabel>Muscle Cramp, CTCAE</classLabel>
<newAxiom>'Muscle Cramp, CTCAE' SubClassOf 'Musculoskeletal and Connective Tissue Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143225</classIRI>
<classLabel>Osteonecrosis, CTCAE</classLabel>
<newAxiom>'Osteonecrosis, CTCAE' SubClassOf 'Musculoskeletal and Connective Tissue Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143226</classIRI>
<classLabel>Rhabdomyolysis, CTCAE</classLabel>
<newAxiom>'Rhabdomyolysis, CTCAE' SubClassOf 'Musculoskeletal and Connective Tissue Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143227</classIRI>
<classLabel>Rotator Cuff Injury, CTCAE</classLabel>
<newAxiom>'Rotator Cuff Injury, CTCAE' SubClassOf 'Musculoskeletal and Connective Tissue Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143217</classIRI>
<classLabel>Blood Bicarbonate Decreased, CTCAE</classLabel>
<newAxiom>'Blood Bicarbonate Decreased, CTCAE' SubClassOf 'Investigations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143218</classIRI>
<classLabel>Blood Lactate Dehydrogenase Increased, CTCAE</classLabel>
<newAxiom>'Blood Lactate Dehydrogenase Increased, CTCAE' SubClassOf 'Investigations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143219</classIRI>
<classLabel>Electrocardiogram T Wave Abnormal, CTCAE</classLabel>
<newAxiom>'Electrocardiogram T Wave Abnormal, CTCAE' SubClassOf 'Investigations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143210</classIRI>
<classLabel>Fungemia, CTCAE</classLabel>
<newAxiom>'Fungemia, CTCAE' SubClassOf 'Infections and Infestations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143211</classIRI>
<classLabel>Hepatitis B Reactivation, CTCAE</classLabel>
<newAxiom>'Hepatitis B Reactivation, CTCAE' SubClassOf 'Infections and Infestations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143212</classIRI>
<classLabel>Herpes Simplex Reactivation, CTCAE</classLabel>
<newAxiom>'Herpes Simplex Reactivation, CTCAE' SubClassOf 'Infections and Infestations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143213</classIRI>
<classLabel>Shingles, CTCAE</classLabel>
<newAxiom>'Shingles, CTCAE' SubClassOf 'Infections and Infestations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143214</classIRI>
<classLabel>Thrush, CTCAE</classLabel>
<newAxiom>'Thrush, CTCAE' SubClassOf 'Infections and Infestations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143215</classIRI>
<classLabel>Viremia, CTCAE</classLabel>
<newAxiom>'Viremia, CTCAE' SubClassOf 'Infections and Infestations, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143216</classIRI>
<classLabel>Vaccination Complication, CTCAE</classLabel>
<newAxiom>'Vaccination Complication, CTCAE' SubClassOf 'Injury, Poisoning and Procedural Complications, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143250</classIRI>
<classLabel>Immune Checkpoint Inhibitor</classLabel>
<newAxiom>'Immune Checkpoint Inhibitor' SubClassOf 'Immune Checkpoint Modulator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143251</classIRI>
<classLabel>Anti-CD123 ADC IMGN632</classLabel>
<newAxiom>'Anti-CD123 ADC IMGN632' SubClassOf 'Immunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143242</classIRI>
<classLabel>Rhinorrhea, CTCAE</classLabel>
<newAxiom>'Rhinorrhea, CTCAE' SubClassOf 'Respiratory, Thoracic and Mediastinal Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143243</classIRI>
<classLabel>Eczema, CTCAE</classLabel>
<newAxiom>'Eczema, CTCAE' SubClassOf 'Skin and Subcutaneous Tissue Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143244</classIRI>
<classLabel>Hair Color Changes, CTCAE</classLabel>
<newAxiom>'Hair Color Changes, CTCAE' SubClassOf 'Skin and Subcutaneous Tissue Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143245</classIRI>
<classLabel>Hair Texture Abnormal, CTCAE</classLabel>
<newAxiom>'Hair Texture Abnormal, CTCAE' SubClassOf 'Skin and Subcutaneous Tissue Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143246</classIRI>
<classLabel>Hyperkeratosis, CTCAE</classLabel>
<newAxiom>'Hyperkeratosis, CTCAE' SubClassOf 'Skin and Subcutaneous Tissue Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143247</classIRI>
<classLabel>Nail Changes, CTCAE</classLabel>
<newAxiom>'Nail Changes, CTCAE' SubClassOf 'Skin and Subcutaneous Tissue Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143248</classIRI>
<classLabel>Subcutaneous Emphysema, CTCAE</classLabel>
<newAxiom>'Subcutaneous Emphysema, CTCAE' SubClassOf 'Skin and Subcutaneous Tissue Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143249</classIRI>
<classLabel>Arterial Thromboembolism, CTCAE</classLabel>
<newAxiom>'Arterial Thromboembolism, CTCAE' SubClassOf 'Vascular Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143240</classIRI>
<classLabel>Amenorrhea, CTCAE</classLabel>
<newAxiom>'Amenorrhea, CTCAE' SubClassOf 'Reproductive System and Breast Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143241</classIRI>
<classLabel>Oropharyngeal Pain, CTCAE</classLabel>
<newAxiom>'Oropharyngeal Pain, CTCAE' SubClassOf 'Respiratory, Thoracic and Mediastinal Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143239</classIRI>
<classLabel>Nephrotic Syndrome, CTCAE</classLabel>
<newAxiom>'Nephrotic Syndrome, CTCAE' SubClassOf 'Renal and Urinary Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143231</classIRI>
<classLabel>Guillain-Barre Syndrome, CTCAE</classLabel>
<newAxiom>'Guillain-Barre Syndrome, CTCAE' SubClassOf 'Nervous System Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143232</classIRI>
<classLabel>Myasthenia Gravis, CTCAE</classLabel>
<newAxiom>'Myasthenia Gravis, CTCAE' SubClassOf 'Nervous System Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143233</classIRI>
<classLabel>Spinal Cord Compression, CTCAE</classLabel>
<newAxiom>'Spinal Cord Compression, CTCAE' SubClassOf 'Nervous System Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143234</classIRI>
<classLabel>Tendon Reflex Decreased, CTCAE</classLabel>
<newAxiom>'Tendon Reflex Decreased, CTCAE' SubClassOf 'Nervous System Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143235</classIRI>
<classLabel>Trochlear Nerve Disorder, CTCAE</classLabel>
<newAxiom>'Trochlear Nerve Disorder, CTCAE' SubClassOf 'Nervous System Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143236</classIRI>
<classLabel>Pregnancy Loss, CTCAE</classLabel>
<newAxiom>'Pregnancy Loss, CTCAE' SubClassOf 'Pregnancy, Puerperium and Perinatal Conditions, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143237</classIRI>
<classLabel>Dysuria, CTCAE</classLabel>
<newAxiom>'Dysuria, CTCAE' SubClassOf 'Renal and Urinary Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143238</classIRI>
<classLabel>Glucosuria, CTCAE</classLabel>
<newAxiom>'Glucosuria, CTCAE' SubClassOf 'Renal and Urinary Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143198</classIRI>
<classLabel>Belching, CTCAE</classLabel>
<newAxiom>'Belching, CTCAE' SubClassOf 'Gastrointestinal Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143199</classIRI>
<classLabel>Chylous Ascites, CTCAE</classLabel>
<newAxiom>'Chylous Ascites, CTCAE' SubClassOf 'Gastrointestinal Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143050</classIRI>
<classLabel>CRNKL1 wt Allele</classLabel>
<newAxiom>'CRNKL1 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Spliceosome Pathway'</newAxiom>
<newAxiom>'CRNKL1 wt Allele' SubClassOf 'CRNKL1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143051</classIRI>
<classLabel>Crooked Neck-Like Protein 1</classLabel>
<newAxiom>'Crooked Neck-Like Protein 1' SubClassOf 'RNA Binding Protein'</newAxiom>
<newAxiom>'Crooked Neck-Like Protein 1' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Splicing'</newAxiom>
<newAxiom>'Crooked Neck-Like Protein 1' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Nucleus'</newAxiom>
<newAxiom>'Crooked Neck-Like Protein 1' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'CRNKL1 Gene'</newAxiom>
<newAxiom>'Crooked Neck-Like Protein 1' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'Proline-Rich Domain'</newAxiom>
<newAxiom>'Crooked Neck-Like Protein 1' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143052</classIRI>
<classLabel>COL3A1 Gene</classLabel>
<newAxiom>'COL3A1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Platelet Activation'</newAxiom>
<newAxiom>'COL3A1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Intercellular Communication Process'</newAxiom>
<newAxiom>'COL3A1 Gene' SubClassOf 'Collagen Gene'</newAxiom>
<newAxiom>'COL3A1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell-Matrix Adhesion Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143053</classIRI>
<classLabel>COL3A1 wt Allele</classLabel>
<newAxiom>'COL3A1 wt Allele' EquivalentTo 'COL3A1 Gene' and ('Gene_Is_Element_In_Pathway' some 'Amoebiasis Pathway') and ('Gene_In_Chromosomal_Location' some '2q32.2')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143054</classIRI>
<classLabel>COL3A1 Gene Product</classLabel>
<newAxiom>'COL3A1 Gene Product' SubClassOf 'Collagen'</newAxiom>
<newAxiom>'COL3A1 Gene Product' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'COL3A1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143044</classIRI>
<classLabel>CUB and Sushi Domain-Containing Protein 3</classLabel>
<newAxiom>'CUB and Sushi Domain-Containing Protein 3' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'Sushi Domain'</newAxiom>
<newAxiom>'CUB and Sushi Domain-Containing Protein 3' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain'</newAxiom>
<newAxiom>'CUB and Sushi Domain-Containing Protein 3' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane'</newAxiom>
<newAxiom>'CUB and Sushi Domain-Containing Protein 3' SubClassOf 'Regulatory Protein'</newAxiom>
<newAxiom>'CUB and Sushi Domain-Containing Protein 3' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'CSMD3 Gene'</newAxiom>
<newAxiom>'CUB and Sushi Domain-Containing Protein 3' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Developmental Process'</newAxiom>
<newAxiom>'CUB and Sushi Domain-Containing Protein 3' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Surface Extension'</newAxiom>
<newAxiom>'CUB and Sushi Domain-Containing Protein 3' SubClassOf 'Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143045</classIRI>
<classLabel>Quinuclium Bromide Anhydrous</classLabel>
<newAxiom>'Quinuclium Bromide Anhydrous' SubClassOf 'Antihypertensive Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143046</classIRI>
<classLabel>Ralimetinib</classLabel>
<newAxiom>'Ralimetinib' SubClassOf 'Serine/Threonine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143047</classIRI>
<classLabel>Derazantinib Dihydrochloride</classLabel>
<newAxiom>'Derazantinib Dihydrochloride' SubClassOf 'Tyrosine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143048</classIRI>
<classLabel>National Cancer Institute Terminology</classLabel>
<newAxiom>'National Cancer Institute Terminology' SubClassOf 'Terminology Subset'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143049</classIRI>
<classLabel>CRNKL1 Gene</classLabel>
<newAxiom>'CRNKL1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Binding'</newAxiom>
<newAxiom>'CRNKL1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Splicing'</newAxiom>
<newAxiom>'CRNKL1 Gene' SubClassOf 'Ligand Binding Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143040</classIRI>
<classLabel>CYSLTR2 wt Allele</classLabel>
<newAxiom>'CYSLTR2 wt Allele' EquivalentTo 'CYSLTR2 Gene' and ('Gene_Is_Element_In_Pathway' some 'Eicosanoid Metabolism Pathway') and ('Gene_Is_Element_In_Pathway' some 'Neuroactive Ligand-Receptor Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Calcium-Mediated Signaling Pathway') and ('Gene_In_Chromosomal_Location' some '13q14.2')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143041</classIRI>
<classLabel>Cysteinyl Leukotriene Receptor 2</classLabel>
<newAxiom>'Cysteinyl Leukotriene Receptor 2' EquivalentTo 'G Protein-Coupled Receptor' and ('Gene_Product_Is_Element_In_Pathway' some 'Eicosanoid Metabolism Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Neuroactive Ligand-Receptor Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Calcium-Mediated Signaling Pathway') and ('Gene_Product_Has_Biochemical_Function' some 'Leukotriene Receptor Family') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Lipid Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'G Protein-Coupled Receptor Signaling') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Leukotriene Receptor Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Leukotriene Activity Induction') and ('Gene_Product_Encoded_By_Gene' some 'CYSLTR2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143042</classIRI>
<classLabel>CSMD3 Gene</classLabel>
<newAxiom>'CSMD3 Gene' SubClassOf 'Regulatory Gene'</newAxiom>
<newAxiom>'CSMD3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell Surface Extension'</newAxiom>
<newAxiom>'CSMD3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Developmental Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143043</classIRI>
<classLabel>CSMD3 wt Allele</classLabel>
<newAxiom>'CSMD3 wt Allele' SubClassOf 'CSMD3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143033</classIRI>
<classLabel>APOBEC1 Complementation Factor</classLabel>
<newAxiom>'APOBEC1 Complementation Factor' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'A1CF Gene'</newAxiom>
<newAxiom>'APOBEC1 Complementation Factor' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Nucleus'</newAxiom>
<newAxiom>'APOBEC1 Complementation Factor' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Processing'</newAxiom>
<newAxiom>'APOBEC1 Complementation Factor' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'RNA Recognition Motif'</newAxiom>
<newAxiom>'APOBEC1 Complementation Factor' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Heterochromatin'</newAxiom>
<newAxiom>'APOBEC1 Complementation Factor' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Binding'</newAxiom>
<newAxiom>'APOBEC1 Complementation Factor' SubClassOf 'RNA Binding Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143034</classIRI>
<classLabel>Adenoviral Brachyury Vaccine ETBX-051</classLabel>
<newAxiom>'Adenoviral Brachyury Vaccine ETBX-051' SubClassOf 'Recombinant Viral Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143035</classIRI>
<classLabel>Adenoviral MUC1 Vaccine ETBX-061</classLabel>
<newAxiom>'Adenoviral MUC1 Vaccine ETBX-061' SubClassOf 'Recombinant Viral Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143036</classIRI>
<classLabel>DCAF12L2 Gene</classLabel>
<newAxiom>'DCAF12L2 Gene' SubClassOf 'Ligand Binding Protein Gene'</newAxiom>
<newAxiom>'DCAF12L2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein-Protein Interaction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143037</classIRI>
<classLabel>DCAF12L2 wt Allele</classLabel>
<newAxiom>'DCAF12L2 wt Allele' SubClassOf 'DCAF12L2 Gene'</newAxiom>
<newAxiom>'DCAF12L2 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some 'Xq25'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143038</classIRI>
<classLabel>DDB1- and CUL4-Associated Factor 12-Like Protein 2</classLabel>
<newAxiom>'DDB1- and CUL4-Associated Factor 12-Like Protein 2' SubClassOf 'Ligand Binding Protein'</newAxiom>
<newAxiom>'DDB1- and CUL4-Associated Factor 12-Like Protein 2' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'WD Repeat'</newAxiom>
<newAxiom>'DDB1- and CUL4-Associated Factor 12-Like Protein 2' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Protein Interaction'</newAxiom>
<newAxiom>'DDB1- and CUL4-Associated Factor 12-Like Protein 2' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'DCAF12L2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143039</classIRI>
<classLabel>CYSLTR2 Gene</classLabel>
<newAxiom>'CYSLTR2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Lipid Binding'</newAxiom>
<newAxiom>'CYSLTR2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Leukotriene Activity Induction'</newAxiom>
<newAxiom>'CYSLTR2 Gene' SubClassOf 'G Protein-Coupled Receptor Gene'</newAxiom>
<newAxiom>'CYSLTR2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'G Protein-Coupled Receptor Signaling'</newAxiom>
<newAxiom>'CYSLTR2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Leukotriene Receptor Binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143070</classIRI>
<classLabel>POLG wt Allele</classLabel>
<newAxiom>'POLG wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '15q26.1'</newAxiom>
<newAxiom>'POLG wt Allele' SubClassOf 'POLG Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143071</classIRI>
<classLabel>DNA Polymerase Subunit Gamma-1</classLabel>
<newAxiom>'DNA Polymerase Subunit Gamma-1' EquivalentTo 'DNA-directed DNA Polymerase' and 'DNA Repair Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleus') and ('Gene_Product_Has_Associated_Anatomy' some 'Mitochondrion') and ('Gene_Product_Has_Biochemical_Function' some 'DNA Exonuclease') and ('Gene_Product_Has_Biochemical_Function' some '3'-5' Exonuclease') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Replication') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Base Excision Repair') and ('Gene_Product_Encoded_By_Gene' some 'POLK Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143072</classIRI>
<classLabel>PABPC1 Gene</classLabel>
<newAxiom>'PABPC1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Polyadenylation'</newAxiom>
<newAxiom>'PABPC1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Nonsense-Mediated Decay'</newAxiom>
<newAxiom>'PABPC1 Gene' SubClassOf 'Ligand Binding Protein Gene'</newAxiom>
<newAxiom>'PABPC1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143073</classIRI>
<classLabel>PABPC1 wt Allele</classLabel>
<newAxiom>'PABPC1 wt Allele' EquivalentTo 'PABPC1 Gene' and ('Gene_Is_Element_In_Pathway' some 'eIF4 Regulation Pathway') and ('Gene_Is_Element_In_Pathway' some 'RNA Degradation Pathway')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143074</classIRI>
<classLabel>Polyadenylate-Binding Protein 1</classLabel>
<newAxiom>'Polyadenylate-Binding Protein 1' EquivalentTo 'RNA Binding Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'eIF4 Regulation Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'RNA Degradation Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleus') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoplasm') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'RNA Recognition Motif') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Polyadenylation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Nonsense-Mediated Decay') and ('Gene_Product_Encoded_By_Gene' some 'PABPC1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143075</classIRI>
<classLabel>NBEA Gene</classLabel>
<newAxiom>'NBEA Gene' SubClassOf 'Adaptor Signaling Protein Gene'</newAxiom>
<newAxiom>'NBEA Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Signal Transduction'</newAxiom>
<newAxiom>'NBEA Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Subcellular Protein Targeting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143076</classIRI>
<classLabel>NBEA wt Allele</classLabel>
<newAxiom>'NBEA wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '13q13.3'</newAxiom>
<newAxiom>'NBEA wt Allele' SubClassOf 'NBEA Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143066</classIRI>
<classLabel>La-Related Protein 4B</classLabel>
<newAxiom>'La-Related Protein 4B' EquivalentTo 'Translation Process Protein' and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'RNA Recognition Motif') and ('Gene_Product_Has_Biochemical_Function' some 'RNA Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Translational Activation') and ('Gene_Product_Encoded_By_Gene' some 'LARP4B Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143067</classIRI>
<classLabel>FGFR4 Antagonist INCB062079</classLabel>
<newAxiom>'FGFR4 Antagonist INCB062079' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143068</classIRI>
<classLabel>IDO-1 Inhibitor LY3381916</classLabel>
<newAxiom>'IDO-1 Inhibitor LY3381916' SubClassOf 'IDO Inhibitor'</newAxiom>
<newAxiom>'IDO-1 Inhibitor LY3381916' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143069</classIRI>
<classLabel>POLG Gene</classLabel>
<newAxiom>'POLG Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'DNA Replication'</newAxiom>
<newAxiom>'POLG Gene' SubClassOf 'DNA Repair Gene'</newAxiom>
<newAxiom>'POLG Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Base Excision Repair'</newAxiom>
<newAxiom>'POLG Gene' SubClassOf 'Polymerase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143060</classIRI>
<classLabel>Autologous Gamma-retroviral MSGV1 139 scFv EGFRvIII CAR Gene-modified T Cells</classLabel>
<newAxiom>'Autologous Gamma-retroviral MSGV1 139 scFv EGFRvIII CAR Gene-modified T Cells' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143061</classIRI>
<classLabel>CHST11 Gene</classLabel>
<newAxiom>'CHST11 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Biosynthetic Process'</newAxiom>
<newAxiom>'CHST11 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Carbohydrate Metabolic Process'</newAxiom>
<newAxiom>'CHST11 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Metabolism Process'</newAxiom>
<newAxiom>'CHST11 Gene' SubClassOf 'Transferase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143062</classIRI>
<classLabel>CHST11 wt Allele</classLabel>
<newAxiom>'CHST11 wt Allele' SubClassOf 'CHST11 Gene'</newAxiom>
<newAxiom>'CHST11 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Glycosaminoglycan Biosynthesis Pathway - Chondroitin Sulfate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143063</classIRI>
<classLabel>Carbohydrate Sulfotransferase 11</classLabel>
<newAxiom>'Carbohydrate Sulfotransferase 11' EquivalentTo 'Transferase' and ('Gene_Product_Is_Element_In_Pathway' some 'Glycosaminoglycan Biosynthesis Pathway - Chondroitin Sulfate') and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Golgi Apparatus') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Sulfotransferase') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Biosynthetic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Carbohydrate Metabolic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Metabolism Process') and ('Gene_Product_Encoded_By_Gene' some 'CHST11 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143064</classIRI>
<classLabel>LARP4B Gene</classLabel>
<newAxiom>'LARP4B Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Binding'</newAxiom>
<newAxiom>'LARP4B Gene' SubClassOf 'Translation Process Gene'</newAxiom>
<newAxiom>'LARP4B Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Translational Activation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143065</classIRI>
<classLabel>LARP4B wt Allele</classLabel>
<newAxiom>'LARP4B wt Allele' SubClassOf 'LARP4B Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143055</classIRI>
<classLabel>Collagen Alpha-1(III) Chain</classLabel>
<newAxiom>'Collagen Alpha-1(III) Chain' EquivalentTo 'COL3A1 Gene Product' and ('Gene_Product_Is_Element_In_Pathway' some 'Amoebiasis Pathway') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Intercellular Communication Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Platelet Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Adhesion Process') and ('Gene_Product_Encoded_By_Gene' some 'COL3A1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143056</classIRI>
<classLabel>CNBD1 Gene</classLabel>
<newAxiom>'CNBD1 Gene' SubClassOf 'Ligand Binding Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143057</classIRI>
<classLabel>CNBD1 wt Allele</classLabel>
<newAxiom>'CNBD1 wt Allele' SubClassOf 'CNBD1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143058</classIRI>
<classLabel>Cyclic Nucleotide-Binding Domain-Containing Protein 1</classLabel>
<newAxiom>'Cyclic Nucleotide-Binding Domain-Containing Protein 1' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'Proline-Rich Domain'</newAxiom>
<newAxiom>'Cyclic Nucleotide-Binding Domain-Containing Protein 1' SubClassOf 'Ligand Binding Protein'</newAxiom>
<newAxiom>'Cyclic Nucleotide-Binding Domain-Containing Protein 1' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'CNBD1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143059</classIRI>
<classLabel>Prime Cancer Vaccine MVA-BN-CV301</classLabel>
<newAxiom>'Prime Cancer Vaccine MVA-BN-CV301' SubClassOf 'Recombinant Vaccinia-TRICOM Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143010</classIRI>
<classLabel>Ropporin-1A</classLabel>
<newAxiom>'Ropporin-1A' SubClassOf 'Gene_Product_Expressed_In_Tissue' some 'Testis'</newAxiom>
<newAxiom>'Ropporin-1A' SubClassOf 'Gene_Product_Expressed_In_Tissue' some 'Fetal Liver'</newAxiom>
<newAxiom>'Ropporin-1A' SubClassOf 'Regulatory Protein'</newAxiom>
<newAxiom>'Ropporin-1A' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'ROPN1 Gene'</newAxiom>
<newAxiom>'Ropporin-1A' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Tail of the Spermatozoon'</newAxiom>
<newAxiom>'Ropporin-1A' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Reproductive Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143008</classIRI>
<classLabel>ROPN1 Gene</classLabel>
<newAxiom>'ROPN1 Gene' SubClassOf 'Regulatory Gene'</newAxiom>
<newAxiom>'ROPN1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Reproductive Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143009</classIRI>
<classLabel>ROPN1 wt Allele</classLabel>
<newAxiom>'ROPN1 wt Allele' SubClassOf 'ROPN1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143000</classIRI>
<classLabel>Semuloparin Sodium</classLabel>
<newAxiom>'Semuloparin Sodium' SubClassOf 'Anticoagulant Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143001</classIRI>
<classLabel>Sibopirdine Anhydrous</classLabel>
<newAxiom>'Sibopirdine Anhydrous' SubClassOf 'CNS Stimulant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143002</classIRI>
<classLabel>Lifastuzumab</classLabel>
<newAxiom>'Lifastuzumab' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143003</classIRI>
<classLabel>Spirogermanium Hydrochloride</classLabel>
<newAxiom>'Spirogermanium Hydrochloride' SubClassOf 'Immunostimulant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143004</classIRI>
<classLabel>Squalamine</classLabel>
<newAxiom>'Squalamine' SubClassOf 'Endothelial Cell Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143005</classIRI>
<classLabel>Sodium Picosulfate Anhydrous</classLabel>
<newAxiom>'Sodium Picosulfate Anhydrous' SubClassOf 'Laxative'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143006</classIRI>
<classLabel>CpG Oligodeoxynucleotide TLR9 Agonist DV281</classLabel>
<newAxiom>'CpG Oligodeoxynucleotide TLR9 Agonist DV281' SubClassOf 'Immunostimulant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143007</classIRI>
<classLabel>Breath Actuated Nebulizer</classLabel>
<newAxiom>'Breath Actuated Nebulizer' SubClassOf 'Nebulizer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143030</classIRI>
<classLabel>Intraoperative Nerve Monitoring</classLabel>
<newAxiom>'Intraoperative Nerve Monitoring' SubClassOf 'Surgical Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143031</classIRI>
<classLabel>A1CF Gene</classLabel>
<newAxiom>'A1CF Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Binding'</newAxiom>
<newAxiom>'A1CF Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Processing'</newAxiom>
<newAxiom>'A1CF Gene' SubClassOf 'Ligand Binding Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143032</classIRI>
<classLabel>A1CF wt Allele</classLabel>
<newAxiom>'A1CF wt Allele' SubClassOf 'A1CF Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143022</classIRI>
<classLabel>RHPN1 Gene</classLabel>
<newAxiom>'RHPN1 Gene' SubClassOf 'Signaling Pathway Gene'</newAxiom>
<newAxiom>'RHPN1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'GTP Binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143023</classIRI>
<classLabel>RHPN1 wt Allele</classLabel>
<newAxiom>'RHPN1 wt Allele' SubClassOf 'RHPN1 Gene'</newAxiom>
<newAxiom>'RHPN1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '8q24.3'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143024</classIRI>
<classLabel>Rhophilin-1</classLabel>
<newAxiom>'Rhophilin-1' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'RHPN1 Gene'</newAxiom>
<newAxiom>'Rhophilin-1' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Cytoplasm'</newAxiom>
<newAxiom>'Rhophilin-1' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'PDZ Domain'</newAxiom>
<newAxiom>'Rhophilin-1' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'GTP Binding Domain'</newAxiom>
<newAxiom>'Rhophilin-1' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'GTP Binding'</newAxiom>
<newAxiom>'Rhophilin-1' SubClassOf 'Signaling Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143025</classIRI>
<classLabel>Pinacidil Anhydrous</classLabel>
<newAxiom>'Pinacidil Anhydrous' SubClassOf 'Antihypertensive Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143026</classIRI>
<classLabel>TNFSF18 Gene</classLabel>
<newAxiom>'TNFSF18 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Intercellular Communication Process'</newAxiom>
<newAxiom>'TNFSF18 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'T-Cell Activation'</newAxiom>
<newAxiom>'TNFSF18 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'T-Cell Proliferation'</newAxiom>
<newAxiom>'TNFSF18 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Chemotaxis Induction'</newAxiom>
<newAxiom>'TNFSF18 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Leukocyte Trafficking Induction'</newAxiom>
<newAxiom>'TNFSF18 Gene' SubClassOf 'Tumor Necrosis Factor Family Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143027</classIRI>
<classLabel>TNFSF18 wt Allele</classLabel>
<newAxiom>'TNFSF18 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Cytokine-Cytokine Receptor Signaling Pathway'</newAxiom>
<newAxiom>'TNFSF18 wt Allele' SubClassOf 'TNFSF18 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143028</classIRI>
<classLabel>Formalin-Fixed Paraffin-Embedded</classLabel>
<newAxiom>'Formalin-Fixed Paraffin-Embedded' SubClassOf 'Tissue Preparation or Processing Technique'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143029</classIRI>
<classLabel>Waterpipe</classLabel>
<newAxiom>'Waterpipe' SubClassOf 'Manufactured Object'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143020</classIRI>
<classLabel>METAP2 wt Allele</classLabel>
<newAxiom>'METAP2 wt Allele' SubClassOf 'METAP2 Gene'</newAxiom>
<newAxiom>'METAP2 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '12q22'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143021</classIRI>
<classLabel>Methionine Aminopeptidase 2</classLabel>
<newAxiom>'Methionine Aminopeptidase 2' EquivalentTo 'Metallopeptidase' and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoplasm') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Proteolysis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Proteolytic Processing') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Translational Regulation') and ('Gene_Product_Encoded_By_Gene' some 'METAP2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143019</classIRI>
<classLabel>METAP2 Gene</classLabel>
<newAxiom>'METAP2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Proteolysis'</newAxiom>
<newAxiom>'METAP2 Gene' SubClassOf 'Metallopeptidase Gene'</newAxiom>
<newAxiom>'METAP2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Translational Regulation'</newAxiom>
<newAxiom>'METAP2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Proteolytic Processing'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143012</classIRI>
<classLabel>Recurrent Skin Squamous Cell Carcinoma</classLabel>
<newAxiom>'Recurrent Skin Squamous Cell Carcinoma' EquivalentTo 'Skin Squamous Cell Carcinoma' and 'Recurrent Skin Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143013</classIRI>
<classLabel>Metastatic Skin Squamous Cell Carcinoma</classLabel>
<newAxiom>'Metastatic Skin Squamous Cell Carcinoma' EquivalentTo 'Metastatic Squamous Cell Carcinoma' and 'Skin Squamous Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143014</classIRI>
<classLabel>Neurofibromatosis Type 1 with Inoperable, Progressive, Symptomatic Plexiform Neurofibromas</classLabel>
<newAxiom>'Neurofibromatosis Type 1 with Inoperable, Progressive, Symptomatic Plexiform Neurofibromas' EquivalentTo 'Neurofibromatosis Type 1' and ('Disease_Has_Finding' some 'Inoperable Disease') and ('Disease_Has_Finding' some 'Progressive Disease') and ('Disease_Has_Associated_Disease' some 'Plexiform Neurofibroma')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143015</classIRI>
<classLabel>Inoperable Disease</classLabel>
<newAxiom>'Inoperable Disease' SubClassOf 'Clinical Course of Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143016</classIRI>
<classLabel>WDR26 Gene</classLabel>
<newAxiom>'WDR26 Gene' SubClassOf 'Adaptor Signaling Protein Gene'</newAxiom>
<newAxiom>'WDR26 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein-Protein Interaction'</newAxiom>
<newAxiom>'WDR26 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'G Protein-Coupled Receptor Signaling'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143017</classIRI>
<classLabel>WDR26 wt Allele</classLabel>
<newAxiom>'WDR26 wt Allele' SubClassOf 'WDR26 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143018</classIRI>
<classLabel>WD Repeat-Containing Protein 26</classLabel>
<newAxiom>'WD Repeat-Containing Protein 26' EquivalentTo 'Adaptor Signaling Protein' and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'WD Repeat') and ('Gene_Product_Has_Biochemical_Function' some 'Scaffolding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Protein Interaction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'G Protein-Coupled Receptor Signaling') and ('Gene_Product_Encoded_By_Gene' some 'WDR26 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143107</classIRI>
<classLabel>WNK2 wt Allele</classLabel>
<newAxiom>'WNK2 wt Allele' SubClassOf 'WNK2 Gene'</newAxiom>
<newAxiom>'WNK2 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '9q22.31'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143108</classIRI>
<classLabel>Serine/Threonine-Protein Kinase WNK2</classLabel>
<newAxiom>'Serine/Threonine-Protein Kinase WNK2' EquivalentTo 'Serine/Threonine Protein Kinase' and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Serine/Threonine Phosphorylation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Homeostatic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Ion Transport Process') and ('Gene_Product_Encoded_By_Gene' some 'WNK2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143109</classIRI>
<classLabel>FAM47C Gene</classLabel>
<newAxiom>'FAM47C Gene' SubClassOf 'Regulatory Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143100</classIRI>
<classLabel>ZNF429 Gene</classLabel>
<newAxiom>'ZNF429 Gene' SubClassOf 'Transcription Regulation Gene'</newAxiom>
<newAxiom>'ZNF429 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Regulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143101</classIRI>
<classLabel>ZNF429 wt Allele</classLabel>
<newAxiom>'ZNF429 wt Allele' SubClassOf 'ZNF429 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143102</classIRI>
<classLabel>Zinc Finger Protein 429</classLabel>
<newAxiom>'Zinc Finger Protein 429' SubClassOf 'Transcription Regulatory Protein'</newAxiom>
<newAxiom>'Zinc Finger Protein 429' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'C2H2 Zinc Finger'</newAxiom>
<newAxiom>'Zinc Finger Protein 429' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Regulation'</newAxiom>
<newAxiom>'Zinc Finger Protein 429' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'ZNF429 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143103</classIRI>
<classLabel>ZNF479 Gene</classLabel>
<newAxiom>'ZNF479 Gene' SubClassOf 'Transcription Regulation Gene'</newAxiom>
<newAxiom>'ZNF479 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Regulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143104</classIRI>
<classLabel>ZNF479 wt Allele</classLabel>
<newAxiom>'ZNF479 wt Allele' SubClassOf 'ZNF479 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143105</classIRI>
<classLabel>Zinc Finger Protein 479</classLabel>
<newAxiom>'Zinc Finger Protein 479' SubClassOf 'Gene_Product_Expressed_In_Tissue' some 'Testis'</newAxiom>
<newAxiom>'Zinc Finger Protein 479' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Regulation'</newAxiom>
<newAxiom>'Zinc Finger Protein 479' SubClassOf 'Gene_Product_Expressed_In_Tissue' some 'Fetus'</newAxiom>
<newAxiom>'Zinc Finger Protein 479' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'ZNF479 Gene'</newAxiom>
<newAxiom>'Zinc Finger Protein 479' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'C2H2 Zinc Finger'</newAxiom>
<newAxiom>'Zinc Finger Protein 479' SubClassOf 'Transcription Regulatory Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143106</classIRI>
<classLabel>WNK2 Gene</classLabel>
<newAxiom>'WNK2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Ion Transport Process'</newAxiom>
<newAxiom>'WNK2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Serine/Threonine Phosphorylation'</newAxiom>
<newAxiom>'WNK2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Homeostatic Process'</newAxiom>
<newAxiom>'WNK2 Gene' SubClassOf 'Serine/Threonine Protein Kinase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143170</classIRI>
<classLabel>Hepatobiliary Disorders, CTCAE</classLabel>
<newAxiom>'Hepatobiliary Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143171</classIRI>
<classLabel>Infections and Infestations, CTCAE</classLabel>
<newAxiom>'Infections and Infestations, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143172</classIRI>
<classLabel>Injury, Poisoning and Procedural Complications, CTCAE</classLabel>
<newAxiom>'Injury, Poisoning and Procedural Complications, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143173</classIRI>
<classLabel>Investigations, CTCAE</classLabel>
<newAxiom>'Investigations, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143174</classIRI>
<classLabel>Metabolism and Nutrition Disorders, CTCAE</classLabel>
<newAxiom>'Metabolism and Nutrition Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143175</classIRI>
<classLabel>Musculoskeletal and Connective Tissue Disorders, CTCAE</classLabel>
<newAxiom>'Musculoskeletal and Connective Tissue Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143165</classIRI>
<classLabel>Cardiac Disorders, CTCAE</classLabel>
<newAxiom>'Cardiac Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143166</classIRI>
<classLabel>Endocrine Disorders, CTCAE</classLabel>
<newAxiom>'Endocrine Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143167</classIRI>
<classLabel>Eye Disorders, CTCAE</classLabel>
<newAxiom>'Eye Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143168</classIRI>
<classLabel>Gastrointestinal Disorders, CTCAE</classLabel>
<newAxiom>'Gastrointestinal Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143169</classIRI>
<classLabel>General Disorders and Administration Site Conditions, CTCAE</classLabel>
<newAxiom>'General Disorders and Administration Site Conditions, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143160</classIRI>
<classLabel>Life Expectancy Greater than Six Months</classLabel>
<newAxiom>'Life Expectancy Greater than Six Months' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143161</classIRI>
<classLabel>Prostate Specific Antigen Density</classLabel>
<newAxiom>'Prostate Specific Antigen Density' SubClassOf 'Prostate Specific Antigen Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143162</classIRI>
<classLabel>PLK1 Inhibitor PCM-075</classLabel>
<newAxiom>'PLK1 Inhibitor PCM-075' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'PLK1 Inhibitor PCM-075' SubClassOf 'Serine/Threonine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143163</classIRI>
<classLabel>CTCAE by Body System</classLabel>
<newAxiom>'CTCAE by Body System' SubClassOf 'Adverse Event'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143164</classIRI>
<classLabel>Blood and Lymphatic System Disorders, CTCAE</classLabel>
<newAxiom>'Blood and Lymphatic System Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143154</classIRI>
<classLabel>Blasts Under 30 Percent of Peripheral Blood White Cells</classLabel>
<newAxiom>'Blasts Under 30 Percent of Peripheral Blood White Cells' SubClassOf 'Blast Cells Present in Peripheral Blood'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143155</classIRI>
<classLabel>Trimeric GITRL-Fc OMP-336B11</classLabel>
<newAxiom>'Trimeric GITRL-Fc OMP-336B11' SubClassOf 'Immunotherapeutic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143156</classIRI>
<classLabel>Anti-CD19-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocytes</classLabel>
<newAxiom>'Anti-CD19-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocytes' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Anti-CD19-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocytes' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Anti-CD19-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocytes' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143157</classIRI>
<classLabel>Allogeneic Nicotinamide-expanded Natural Killer Cells</classLabel>
<newAxiom>'Allogeneic Nicotinamide-expanded Natural Killer Cells' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Allogeneic Nicotinamide-expanded Natural Killer Cells' SubClassOf 'Therapeutic Allogeneic Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143158</classIRI>
<classLabel>Microtubule Inhibitor SCB01A</classLabel>
<newAxiom>'Microtubule Inhibitor SCB01A' SubClassOf 'Tubulin Binding Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143159</classIRI>
<classLabel>Hou Gu Mi Xi</classLabel>
<newAxiom>'Hou Gu Mi Xi' SubClassOf 'Traditional Chinese Medicine Formulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143190</classIRI>
<classLabel>Eosinophilia, CTCAE</classLabel>
<newAxiom>'Eosinophilia, CTCAE' SubClassOf 'Blood and Lymphatic System Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143191</classIRI>
<classLabel>Methemoglobinemia, CTCAE</classLabel>
<newAxiom>'Methemoglobinemia, CTCAE' SubClassOf 'Blood and Lymphatic System Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143192</classIRI>
<classLabel>Cyanosis, CTCAE</classLabel>
<newAxiom>'Cyanosis, CTCAE' SubClassOf 'Cardiac Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143193</classIRI>
<classLabel>Hypophysitis, CTCAE</classLabel>
<newAxiom>'Hypophysitis, CTCAE' SubClassOf 'Endocrine Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143194</classIRI>
<classLabel>Hypopituitarism, CTCAE</classLabel>
<newAxiom>'Hypopituitarism, CTCAE' SubClassOf 'Endocrine Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143195</classIRI>
<classLabel>Testosterone Deficiency, CTCAE</classLabel>
<newAxiom>'Testosterone Deficiency, CTCAE' SubClassOf 'Endocrine Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143196</classIRI>
<classLabel>Vision Decreased, CTCAE</classLabel>
<newAxiom>'Vision Decreased, CTCAE' SubClassOf 'Eye Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143197</classIRI>
<classLabel>Anal Fissure, CTCAE</classLabel>
<newAxiom>'Anal Fissure, CTCAE' SubClassOf 'Gastrointestinal Disorders, CTCAE'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143187</classIRI>
<classLabel>Psychiatric Disorders, CTCAE</classLabel>
<newAxiom>'Psychiatric Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143188</classIRI>
<classLabel>Social Circumstances, CTCAE</classLabel>
<newAxiom>'Social Circumstances, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143189</classIRI>
<classLabel>Surgical and Medical Procedures, CTCAE</classLabel>
<newAxiom>'Surgical and Medical Procedures, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143180</classIRI>
<classLabel>Reproductive System and Breast Disorders, CTCAE</classLabel>
<newAxiom>'Reproductive System and Breast Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143181</classIRI>
<classLabel>Respiratory, Thoracic and Mediastinal Disorders, CTCAE</classLabel>
<newAxiom>'Respiratory, Thoracic and Mediastinal Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143182</classIRI>
<classLabel>Skin and Subcutaneous Tissue Disorders, CTCAE</classLabel>
<newAxiom>'Skin and Subcutaneous Tissue Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143183</classIRI>
<classLabel>Vascular Disorders, CTCAE</classLabel>
<newAxiom>'Vascular Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143184</classIRI>
<classLabel>Congenital, Familial and Genetic Disorders, CTCAE</classLabel>
<newAxiom>'Congenital, Familial and Genetic Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143185</classIRI>
<classLabel>Ear and Labyrinth Disorders, CTCAE</classLabel>
<newAxiom>'Ear and Labyrinth Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143186</classIRI>
<classLabel>Immune System Disorders, CTCAE</classLabel>
<newAxiom>'Immune System Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143176</classIRI>
<classLabel>Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps), CTCAE</classLabel>
<newAxiom>'Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps), CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143177</classIRI>
<classLabel>Nervous System Disorders, CTCAE</classLabel>
<newAxiom>'Nervous System Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143178</classIRI>
<classLabel>Pregnancy, Puerperium and Perinatal Conditions, CTCAE</classLabel>
<newAxiom>'Pregnancy, Puerperium and Perinatal Conditions, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143179</classIRI>
<classLabel>Renal and Urinary Disorders, CTCAE</classLabel>
<newAxiom>'Renal and Urinary Disorders, CTCAE' SubClassOf 'CTCAE by Body System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143130</classIRI>
<classLabel>FBLN2 Gene</classLabel>
<newAxiom>'FBLN2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein-Protein Interaction'</newAxiom>
<newAxiom>'FBLN2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Calcium Binding'</newAxiom>
<newAxiom>'FBLN2 Gene' SubClassOf 'Extracellular Matrix Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143131</classIRI>
<classLabel>FBLN2 wt Allele</classLabel>
<newAxiom>'FBLN2 wt Allele' SubClassOf 'FBLN2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143129</classIRI>
<classLabel>Peptidyl-Prolyl Cis-Trans Isomerase FKBP9</classLabel>
<newAxiom>'Peptidyl-Prolyl Cis-Trans Isomerase FKBP9' EquivalentTo 'Isomerase' and ('Gene_Product_Has_Associated_Anatomy' some 'Endoplasmic Reticulum') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'EF-Hand Domain') and ('Gene_Product_Has_Biochemical_Function' some 'FK506 Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Folding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Synthesis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Protein Interaction') and ('Gene_Product_Encoded_By_Gene' some 'FKBP9 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143121</classIRI>
<classLabel>PRDM2 Gene</classLabel>
<newAxiom>'PRDM2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'DNA Binding'</newAxiom>
<newAxiom>'PRDM2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Methylation'</newAxiom>
<newAxiom>'PRDM2 Gene' SubClassOf 'Methyltransferase Gene'</newAxiom>
<newAxiom>'PRDM2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Histone Modification'</newAxiom>
<newAxiom>'PRDM2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Regulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143122</classIRI>
<classLabel>PRDM2 wt Allele</classLabel>
<newAxiom>'PRDM2 wt Allele' SubClassOf 'PRDM2 Gene'</newAxiom>
<newAxiom>'PRDM2 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Lysine Degradation Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143123</classIRI>
<classLabel>PR Domain Zinc Finger Protein 2</classLabel>
<newAxiom>'PR Domain Zinc Finger Protein 2' EquivalentTo 'Methyltransferase' and ('Gene_Product_Is_Element_In_Pathway' some 'Lysine Degradation Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleus') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'C2H2 Zinc Finger') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'SET Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Proline-Rich Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'SH3-Binding Motif') and ('Gene_Product_Has_Biochemical_Function' some 'DNA Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Histone Modification') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Regulation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Methylation') and ('Gene_Product_Encoded_By_Gene' some 'PRDM2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143124</classIRI>
<classLabel>FOXR1 Gene</classLabel>
<newAxiom>'FOXR1 Gene' SubClassOf 'Transcription Factor Gene'</newAxiom>
<newAxiom>'FOXR1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Regulation'</newAxiom>
<newAxiom>'FOXR1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'DNA Binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143125</classIRI>
<classLabel>FOXR1 wt Allele</classLabel>
<newAxiom>'FOXR1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '11q23.3'</newAxiom>
<newAxiom>'FOXR1 wt Allele' SubClassOf 'FOXR1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143126</classIRI>
<classLabel>Forkhead Box Protein R1</classLabel>
<newAxiom>'Forkhead Box Protein R1' EquivalentTo 'Transcription Factor' and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Forkhead Box') and ('Gene_Product_Has_Biochemical_Function' some 'Sequence-Specific DNA Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Regulation') and ('Gene_Product_Encoded_By_Gene' some 'FOXR1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143127</classIRI>
<classLabel>FKBP9 Gene</classLabel>
<newAxiom>'FKBP9 Gene' SubClassOf 'Isomerase Gene'</newAxiom>
<newAxiom>'FKBP9 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Synthesis'</newAxiom>
<newAxiom>'FKBP9 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Folding'</newAxiom>
<newAxiom>'FKBP9 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein-Protein Interaction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143128</classIRI>
<classLabel>FKBP9 wt Allele</classLabel>
<newAxiom>'FKBP9 wt Allele' SubClassOf 'FKBP9 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143120</classIRI>
<classLabel>Regulator of G-Protein Signaling 7</classLabel>
<newAxiom>'Regulator of G-Protein Signaling 7' SubClassOf 'RGS Family Protein'</newAxiom>
<newAxiom>'Regulator of G-Protein Signaling 7' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'RGS7 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143118</classIRI>
<classLabel>RGS7 Gene</classLabel>
<newAxiom>'RGS7 Gene' SubClassOf 'RGS Family Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143119</classIRI>
<classLabel>RGS7 wt Allele</classLabel>
<newAxiom>'RGS7 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '1q43'</newAxiom>
<newAxiom>'RGS7 wt Allele' SubClassOf 'RGS7 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143110</classIRI>
<classLabel>FAM47C wt Allele</classLabel>
<newAxiom>'FAM47C wt Allele' SubClassOf 'FAM47C Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143111</classIRI>
<classLabel>Putative Protein FAM47C</classLabel>
<newAxiom>'Putative Protein FAM47C' SubClassOf 'Regulatory Protein'</newAxiom>
<newAxiom>'Putative Protein FAM47C' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'FAM47C Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143112</classIRI>
<classLabel>FAM135B Gene</classLabel>
<newAxiom>'FAM135B Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Lipid Metabolic Process'</newAxiom>
<newAxiom>'FAM135B Gene' SubClassOf 'Regulatory Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143113</classIRI>
<classLabel>FAM135B wt Allele</classLabel>
<newAxiom>'FAM135B wt Allele' SubClassOf 'FAM135B Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143114</classIRI>
<classLabel>Protein FAM135B</classLabel>
<newAxiom>'Protein FAM135B' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Lipid Metabolic Process'</newAxiom>
<newAxiom>'Protein FAM135B' SubClassOf 'Regulatory Protein'</newAxiom>
<newAxiom>'Protein FAM135B' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'FAM135B Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143115</classIRI>
<classLabel>CTNNA2 Gene</classLabel>
<newAxiom>'CTNNA2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell-Cell Adhesion Process'</newAxiom>
<newAxiom>'CTNNA2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cytoskeletal Process'</newAxiom>
<newAxiom>'CTNNA2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell Differentiation Process'</newAxiom>
<newAxiom>'CTNNA2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein-Protein Interaction'</newAxiom>
<newAxiom>'CTNNA2 Gene' SubClassOf 'Cytoskeletal Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143116</classIRI>
<classLabel>CTNNA2 wt Allele</classLabel>
<newAxiom>'CTNNA2 wt Allele' EquivalentTo 'CTNNA2 Gene' and ('Gene_Is_Element_In_Pathway' some 'Cell to Cell Adhesion Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Leukocyte Transendothelial Migration Pathway') and ('Gene_Is_Element_In_Pathway' some 'Arrhythmogenic Right Ventricular Cardiomyopathy Pathway') and ('Gene_Is_Element_In_Pathway' some 'Adherens Junction Assembly Pathway') and ('Gene_Is_Element_In_Pathway' some 'Endometrial Cancer Pathway') and ('Gene_Is_Element_In_Pathway' some 'Bacterial Invasion of Epithelial Cell Pathway') and ('Gene_In_Chromosomal_Location' some '2p12')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143117</classIRI>
<classLabel>Catenin Alpha-2</classLabel>
<newAxiom>'Catenin Alpha-2' EquivalentTo 'Cytoskeletal Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Cell to Cell Adhesion Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Leukocyte Transendothelial Migration Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Arrhythmogenic Right Ventricular Cardiomyopathy Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Adherens Junction Assembly Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Endometrial Cancer Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Bacterial Invasion of Epithelial Cell Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoskeleton') and ('Gene_Product_Has_Biochemical_Function' some 'Catenin Family Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Differentiation Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Protein Interaction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell-Cell Adhesion Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cytoskeletal Process') and ('Gene_Product_Encoded_By_Gene' some 'CTNNA2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143150</classIRI>
<classLabel>Restriction Spectrum Imaging</classLabel>
<newAxiom>'Restriction Spectrum Imaging' SubClassOf 'Diffusion Weighted Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143151</classIRI>
<classLabel>Masaoka-Koga Stage</classLabel>
<newAxiom>'Masaoka-Koga Stage' SubClassOf 'Disease Stage Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143152</classIRI>
<classLabel>Blasts Under 15 Percent of Peripheral Blood White Cells</classLabel>
<newAxiom>'Blasts Under 15 Percent of Peripheral Blood White Cells' SubClassOf 'Blasts Under 20 Percent of Peripheral Blood White Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143153</classIRI>
<classLabel>Blasts Under 15 Percent of Bone Marrow Nucleated Cells</classLabel>
<newAxiom>'Blasts Under 15 Percent of Bone Marrow Nucleated Cells' SubClassOf 'Blasts Under 20 Percent of Bone Marrow Nucleated Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143143</classIRI>
<classLabel>ARF1 wt Allele</classLabel>
<newAxiom>'ARF1 wt Allele' EquivalentTo 'ARF1 Gene' and ('Gene_Is_Element_In_Pathway' some 'ADP-Ribosylation Pathway') and ('Gene_Is_Element_In_Pathway' some 'Phosphoinositide Pathway') and ('Gene_Is_Element_In_Pathway' some 'Vibrio cholerae Infection Pathway') and ('Gene_Is_Element_In_Pathway' some 'Endocytosis Pathway') and ('Gene_Is_Element_In_Pathway' some 'Arf1 Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Arf6 Signaling Pathway')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143144</classIRI>
<classLabel>ADP-Ribosylation Factor 1</classLabel>
<newAxiom>'ADP-Ribosylation Factor 1' EquivalentTo 'Small G Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'ADP-Ribosylation Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Phosphoinositide Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Vibrio cholerae Infection Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Endocytosis Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Arf1 Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Arf6 Signaling Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Golgi Apparatus') and ('Gene_Product_Has_Associated_Anatomy' some 'Postsynaptic Membrane') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Receptor Mediated Endocytosis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Subcellular Protein Targeting') and ('Gene_Product_Encoded_By_Gene' some 'ARF1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143145</classIRI>
<classLabel>ADP-Ribosylation Factor 6</classLabel>
<newAxiom>'ADP-Ribosylation Factor 6' EquivalentTo 'Small G Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Fc Gamma Receptor-Mediated Phagocytosis Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Arf6 Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Arf6 Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Arf6 Trafficking Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Adherens Junction Formation Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Hepatocyte Growth Factor Receptor Signaling Pathway PID') and ('Gene_Product_Is_Element_In_Pathway' some 'Adherens Junction Stabilization Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Golgi Apparatus') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Endosome') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cytokinesis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Membrane Protein Traffic') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cytoskeletal Modeling') and ('Gene_Product_Encoded_By_Gene' some 'ARF6 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143146</classIRI>
<classLabel>ARF6 Gene</classLabel>
<newAxiom>'ARF6 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cytokinesis'</newAxiom>
<newAxiom>'ARF6 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Membrane Protein Traffic'</newAxiom>
<newAxiom>'ARF6 Gene' SubClassOf 'G Protein Gene'</newAxiom>
<newAxiom>'ARF6 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cytoskeletal Modeling'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143147</classIRI>
<classLabel>ARF6 wt Allele</classLabel>
<newAxiom>'ARF6 wt Allele' EquivalentTo 'ARF6 Gene' and ('Gene_Is_Element_In_Pathway' some 'Endocytosis Pathway') and ('Gene_Is_Element_In_Pathway' some 'Fc Gamma Receptor-Mediated Phagocytosis Pathway') and ('Gene_Is_Element_In_Pathway' some 'Arf6 Pathway') and ('Gene_Is_Element_In_Pathway' some 'Arf6 Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Arf6 Trafficking Pathway') and ('Gene_Is_Element_In_Pathway' some 'Adherens Junction Formation Pathway') and ('Gene_Is_Element_In_Pathway' some 'Hepatocyte Growth Factor Receptor Signaling Pathway PID') and ('Gene_Is_Element_In_Pathway' some 'Adherens Junction Stabilization Pathway') and ('Gene_In_Chromosomal_Location' some '14q21.3')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143148</classIRI>
<classLabel>Transrectal Ultrasonography Guided Biopsy</classLabel>
<newAxiom>'Transrectal Ultrasonography Guided Biopsy' SubClassOf 'Ultrasound-Guided Prostate Biopsy'</newAxiom>
<newAxiom>'Transrectal Ultrasonography Guided Biopsy' SubClassOf 'Transrectal Biopsy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143149</classIRI>
<classLabel>PSA Doubling Time</classLabel>
<newAxiom>'PSA Doubling Time' SubClassOf 'Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143140</classIRI>
<classLabel>Tabelecleucel</classLabel>
<newAxiom>'Tabelecleucel' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Tabelecleucel' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143141</classIRI>
<classLabel>Topical VBP-926 Solution</classLabel>
<newAxiom>'Topical VBP-926 Solution' SubClassOf 'Anti-Infective Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143142</classIRI>
<classLabel>ARF1 Gene</classLabel>
<newAxiom>'ARF1 Gene' SubClassOf 'G Protein Gene'</newAxiom>
<newAxiom>'ARF1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Subcellular Protein Targeting'</newAxiom>
<newAxiom>'ARF1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Lipid Metabolic Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143132</classIRI>
<classLabel>Fibulin-2</classLabel>
<newAxiom>'Fibulin-2' EquivalentTo 'Extracellular Matrix Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Matrix') and ('Gene_Product_Expressed_In_Tissue' some 'Connective Tissue') and ('Gene_Product_Expressed_In_Tissue' some 'Basement Membrane') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'EGF-Like Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Calcium Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Protein Interaction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Calcium Binding')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143133</classIRI>
<classLabel>FAT3 Gene</classLabel>
<newAxiom>'FAT3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Calcium Binding'</newAxiom>
<newAxiom>'FAT3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Neural Development'</newAxiom>
<newAxiom>'FAT3 Gene' SubClassOf 'Cell Adhesion Molecule Gene'</newAxiom>
<newAxiom>'FAT3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell-Cell Adhesion Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143134</classIRI>
<classLabel>FAT3 wt Allele</classLabel>
<newAxiom>'FAT3 wt Allele' SubClassOf 'FAT3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143135</classIRI>
<classLabel>Protocadherin Fat 3</classLabel>
<newAxiom>'Protocadherin Fat 3' EquivalentTo 'Cell Adhesion Molecule' and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Cadherin Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'EGF-Like Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Cadherin') and ('Gene_Product_Has_Biochemical_Function' some 'Calcium Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Neural Development') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell-Cell Adhesion Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Calcium Binding') and ('Gene_Product_Encoded_By_Gene' some 'FAT3 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143136</classIRI>
<classLabel>Retired Concept 2017</classLabel>
<newAxiom>'Retired Concept 2017' SubClassOf 'Retired Concept'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143137</classIRI>
<classLabel>ARFRP1 Gene</classLabel>
<newAxiom>'ARFRP1 Gene' SubClassOf 'G Protein Gene'</newAxiom>
<newAxiom>'ARFRP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Golgi Targeting'</newAxiom>
<newAxiom>'ARFRP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Lipid Metabolic Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143138</classIRI>
<classLabel>ARFRP1 wt Allele</classLabel>
<newAxiom>'ARFRP1 wt Allele' SubClassOf 'ARFRP1 Gene'</newAxiom>
<newAxiom>'ARFRP1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '20q13.33'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143139</classIRI>
<classLabel>ADP-Ribosylation Factor-Related Protein 1</classLabel>
<newAxiom>'ADP-Ribosylation Factor-Related Protein 1' EquivalentTo 'Small G Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Golgi Apparatus') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Lipid Metabolic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Golgi Targeting') and ('Gene_Product_Encoded_By_Gene' some 'ARFRP1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143091</classIRI>
<classLabel>PRPF40B wt Allele</classLabel>
<newAxiom>'PRPF40B wt Allele' SubClassOf 'PRPF40B Gene'</newAxiom>
<newAxiom>'PRPF40B wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Spliceosome Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143092</classIRI>
<classLabel>Pre-mRNA-Processing Factor 40 Homolog B</classLabel>
<newAxiom>'Pre-mRNA-Processing Factor 40 Homolog B' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'PRPF40B Gene'</newAxiom>
<newAxiom>'Pre-mRNA-Processing Factor 40 Homolog B' SubClassOf 'Gene_Product_Is_Element_In_Pathway' some 'Spliceosome Pathway'</newAxiom>
<newAxiom>'Pre-mRNA-Processing Factor 40 Homolog B' SubClassOf 'Regulatory Protein'</newAxiom>
<newAxiom>'Pre-mRNA-Processing Factor 40 Homolog B' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Splicing'</newAxiom>
<newAxiom>'Pre-mRNA-Processing Factor 40 Homolog B' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Nucleus'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143093</classIRI>
<classLabel>CDH10 Gene</classLabel>
<newAxiom>'CDH10 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell-Cell Adhesion Process'</newAxiom>
<newAxiom>'CDH10 Gene' SubClassOf 'Cell Adhesion Molecule Gene'</newAxiom>
<newAxiom>'CDH10 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Regulation of Cell Shape'</newAxiom>
<newAxiom>'CDH10 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Calcium Binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143094</classIRI>
<classLabel>CDH10 wt Allele</classLabel>
<newAxiom>'CDH10 wt Allele' SubClassOf 'CDH10 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143095</classIRI>
<classLabel>Cadherin-10</classLabel>
<newAxiom>'Cadherin-10' EquivalentTo 'Cadherin' and ('Gene_Product_Has_Chemical_Classification' some 'Glycoprotein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Expressed_In_Tissue' some 'Brain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Cadherin Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell-Cell Adhesion Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Regulation of Cell Shape') and ('Gene_Product_Encoded_By_Gene' some 'CDH10 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143096</classIRI>
<classLabel>CDH17 Gene</classLabel>
<newAxiom>'CDH17 Gene' SubClassOf 'Cell Adhesion Molecule Gene'</newAxiom>
<newAxiom>'CDH17 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Calcium Binding'</newAxiom>
<newAxiom>'CDH17 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Peptide Transport'</newAxiom>
<newAxiom>'CDH17 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell-Cell Adhesion Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143097</classIRI>
<classLabel>CDH17 wt Allele</classLabel>
<newAxiom>'CDH17 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '8q22.1'</newAxiom>
<newAxiom>'CDH17 wt Allele' SubClassOf 'CDH17 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143098</classIRI>
<classLabel>Cadherin-17</classLabel>
<newAxiom>'Cadherin-17' EquivalentTo 'Cadherin' and ('Gene_Product_Has_Chemical_Classification' some 'Glycoprotein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Expressed_In_Tissue' some 'Pancreatic Duct') and ('Gene_Product_Expressed_In_Tissue' some 'Gastrointestinal Tract') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Cadherin Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell-Cell Adhesion Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Peptide Transport') and ('Gene_Product_Encoded_By_Gene' some 'CDH17 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143090</classIRI>
<classLabel>PRPF40B Gene</classLabel>
<newAxiom>'PRPF40B Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Splicing'</newAxiom>
<newAxiom>'PRPF40B Gene' SubClassOf 'Regulatory Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143088</classIRI>
<classLabel>Nolatrexed</classLabel>
<newAxiom>'Nolatrexed' SubClassOf 'Thymidylate Synthase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143089</classIRI>
<classLabel>Naflocort Anhydrous</classLabel>
<newAxiom>'Naflocort Anhydrous' SubClassOf 'Therapeutic Glucocorticoid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143080</classIRI>
<classLabel>Protein S100-A7</classLabel>
<newAxiom>'Protein S100-A7' EquivalentTo 'S100 Calcium Binding Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'EF-Hand Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Calcium Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Chemotaxis Induction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Antimicrobial Effect') and ('Gene_Product_Encoded_By_Gene' some 'S100A7 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143081</classIRI>
<classLabel>Posttherapy Clinical TNM Finding</classLabel>
<newAxiom>'Posttherapy Clinical TNM Finding' SubClassOf 'Cancer TNM Finding Category'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143082</classIRI>
<classLabel>RGPD3 Gene</classLabel>
<newAxiom>'RGPD3 Gene' SubClassOf 'Regulatory Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143083</classIRI>
<classLabel>RGPD3 wt Allele</classLabel>
<newAxiom>'RGPD3 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '2q12.2'</newAxiom>
<newAxiom>'RGPD3 wt Allele' SubClassOf 'RGPD3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143084</classIRI>
<classLabel>RanBP2-Like and GRIP Domain-Containing Protein 3</classLabel>
<newAxiom>'RanBP2-Like and GRIP Domain-Containing Protein 3' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'Coiled-Coil Domain'</newAxiom>
<newAxiom>'RanBP2-Like and GRIP Domain-Containing Protein 3' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'RGPD3 Gene'</newAxiom>
<newAxiom>'RanBP2-Like and GRIP Domain-Containing Protein 3' SubClassOf 'Regulatory Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143085</classIRI>
<classLabel>Refractory Marginal Zone Lymphoma</classLabel>
<newAxiom>'Refractory Marginal Zone Lymphoma' EquivalentTo 'Marginal Zone Lymphoma' and 'Refractory Mature B-Cell Non-Hodgkin Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143086</classIRI>
<classLabel>Prajmalium Bitartrate</classLabel>
<newAxiom>'Prajmalium Bitartrate' SubClassOf 'Antiarrhythmic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143087</classIRI>
<classLabel>Maxacalcitol</classLabel>
<newAxiom>'Maxacalcitol' SubClassOf 'Vitamin D Analog'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143077</classIRI>
<classLabel>Neurobeachin</classLabel>
<newAxiom>'Neurobeachin' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Signal Transduction'</newAxiom>
<newAxiom>'Neurobeachin' SubClassOf 'Adaptor Signaling Protein'</newAxiom>
<newAxiom>'Neurobeachin' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Subcellular Protein Targeting'</newAxiom>
<newAxiom>'Neurobeachin' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'NBEA Gene'</newAxiom>
<newAxiom>'Neurobeachin' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'WD Repeat'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143078</classIRI>
<classLabel>S100A7 Gene</classLabel>
<newAxiom>'S100A7 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Calcium Binding'</newAxiom>
<newAxiom>'S100A7 Gene' SubClassOf 'S100 Family Gene'</newAxiom>
<newAxiom>'S100A7 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Chemotaxis Induction'</newAxiom>
<newAxiom>'S100A7 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Antimicrobial Effect'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143079</classIRI>
<classLabel>S100A7 wt Allele</classLabel>
<newAxiom>'S100A7 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '1q21.3'</newAxiom>
<newAxiom>'S100A7 wt Allele' SubClassOf 'S100A7 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143099</classIRI>
<classLabel>c-Met Inhibitor</classLabel>
<newAxiom>'c-Met Inhibitor' SubClassOf 'Tyrosine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142919</classIRI>
<classLabel>Amfenac Sodium</classLabel>
<newAxiom>'Amfenac Sodium' SubClassOf 'Nonsteroidal Antiinflammatory Drug'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142918</classIRI>
<classLabel>Aluminum Sesquichlorohydrate</classLabel>
<newAxiom>'Aluminum Sesquichlorohydrate' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142917</classIRI>
<classLabel>Aluminum Chlorohydrex Propylene Glycol</classLabel>
<newAxiom>'Aluminum Chlorohydrex Propylene Glycol' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142916</classIRI>
<classLabel>Aluminum Chlorohydrate</classLabel>
<newAxiom>'Aluminum Chlorohydrate' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142914</classIRI>
<classLabel>Alphafilcon A</classLabel>
<newAxiom>'Alphafilcon A' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142913</classIRI>
<classLabel>Alniditan Dihydrochloride</classLabel>
<newAxiom>'Alniditan Dihydrochloride' SubClassOf 'Serotonin Agonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142912</classIRI>
<classLabel>Alisertib Sodium</classLabel>
<newAxiom>'Alisertib Sodium' SubClassOf 'Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142911</classIRI>
<classLabel>Alicaforsen Sodium</classLabel>
<newAxiom>'Alicaforsen Sodium' SubClassOf 'Antisense Oligonucleotides'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142910</classIRI>
<classLabel>Alexomycin</classLabel>
<newAxiom>'Alexomycin' SubClassOf 'Antibiotic'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142909</classIRI>
<classLabel>Aldoxorubicin Hydrochloride</classLabel>
<newAxiom>'Aldoxorubicin Hydrochloride' SubClassOf 'Doxorubicin Preparation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142908</classIRI>
<classLabel>Albumin, Aggregated Iodinated I-131 Serum</classLabel>
<newAxiom>'Albumin, Aggregated Iodinated I-131 Serum' SubClassOf 'Radioconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142907</classIRI>
<classLabel>Alamecin</classLabel>
<newAxiom>'Alamecin' SubClassOf 'Antibiotic'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142906</classIRI>
<classLabel>Aladorian Sodium</classLabel>
<newAxiom>'Aladorian Sodium' SubClassOf 'Antiarrhythmic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142904</classIRI>
<classLabel>Aganepag Isopropyl</classLabel>
<newAxiom>'Aganepag Isopropyl' SubClassOf 'Anti-glaucoma Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142903</classIRI>
<classLabel>Aganepag Ethanediol</classLabel>
<newAxiom>'Aganepag Ethanediol' SubClassOf 'Anti-glaucoma Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142902</classIRI>
<classLabel>Afuresertib Hydrochloride</classLabel>
<newAxiom>'Afuresertib Hydrochloride' SubClassOf 'Serine/Threonine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142901</classIRI>
<classLabel>Aftobetin Hydrochloride</classLabel>
<newAxiom>'Aftobetin Hydrochloride' SubClassOf 'Topical Preparation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142900</classIRI>
<classLabel>Afovirsen Sodium</classLabel>
<newAxiom>'Afovirsen Sodium' SubClassOf 'Antisense Oligonucleotides'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142939</classIRI>
<classLabel>Atropine Oxide Hydrochloride</classLabel>
<newAxiom>'Atropine Oxide Hydrochloride' SubClassOf 'Antimuscarinic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142930</classIRI>
<classLabel>Aripiprazole Cavoxil</classLabel>
<newAxiom>'Aripiprazole Cavoxil' SubClassOf 'Antipsychotic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142938</classIRI>
<classLabel>Atopaxar Hydrochloride</classLabel>
<newAxiom>'Atopaxar Hydrochloride' SubClassOf 'Antiplatelet Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142937</classIRI>
<classLabel>Atopaxar Hydrobromide</classLabel>
<newAxiom>'Atopaxar Hydrobromide' SubClassOf 'Antiplatelet Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142936</classIRI>
<classLabel>Atesidorsen Sodium</classLabel>
<newAxiom>'Atesidorsen Sodium' SubClassOf 'Antisense Oligonucleotides'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142935</classIRI>
<classLabel>Asvasiran Sodium</classLabel>
<newAxiom>'Asvasiran Sodium' SubClassOf 'Biological Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142934</classIRI>
<classLabel>Asalhydromorphone Hydrochloride</classLabel>
<newAxiom>'Asalhydromorphone Hydrochloride' SubClassOf 'Analgesic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142933</classIRI>
<classLabel>Asalhydromorphone</classLabel>
<newAxiom>'Asalhydromorphone' SubClassOf 'Analgesic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142932</classIRI>
<classLabel>Artilide Fumarate</classLabel>
<newAxiom>'Artilide Fumarate' SubClassOf 'Antiarrhythmic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142931</classIRI>
<classLabel>Aripiprazole Lauroxil</classLabel>
<newAxiom>'Aripiprazole Lauroxil' SubClassOf 'Antipsychotic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142929</classIRI>
<classLabel>Aptiganel Hydrochloride</classLabel>
<newAxiom>'Aptiganel Hydrochloride' SubClassOf 'Neuroprotective Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142928</classIRI>
<classLabel>Apatorsen Sodium</classLabel>
<newAxiom>'Apatorsen Sodium' SubClassOf 'Antisense Oligonucleotides'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142927</classIRI>
<classLabel>Antimony Trisulfide</classLabel>
<newAxiom>'Antimony Trisulfide' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142926</classIRI>
<classLabel>Anoxomer</classLabel>
<newAxiom>'Anoxomer' SubClassOf 'Food Component'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142925</classIRI>
<classLabel>Anivamersen Sodium</classLabel>
<newAxiom>'Anivamersen Sodium' SubClassOf 'Pharmacologic Substance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142924</classIRI>
<classLabel>Angiotensin II Acetate</classLabel>
<newAxiom>'Angiotensin II Acetate' SubClassOf 'Biological Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142923</classIRI>
<classLabel>Amitifadine Hydrochloride</classLabel>
<newAxiom>'Amitifadine Hydrochloride' SubClassOf 'Antidepressant Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142922</classIRI>
<classLabel>Amiselimod Hydrochloride</classLabel>
<newAxiom>'Amiselimod Hydrochloride' SubClassOf 'Immunosuppressant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142921</classIRI>
<classLabel>Amifampridine Phosphate</classLabel>
<newAxiom>'Amifampridine Phosphate' SubClassOf 'Cation Channel Blocker'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142920</classIRI>
<classLabel>Amicloral</classLabel>
<newAxiom>'Amicloral' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142996</classIRI>
<classLabel>A-Kinase Anchor Protein 4</classLabel>
<newAxiom>'A-Kinase Anchor Protein 4' EquivalentTo 'Adaptor Signaling Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Spermatid') and ('Gene_Product_Has_Associated_Anatomy' some 'Tail of the Spermatozoon') and ('Gene_Product_Expressed_In_Tissue' some 'Testis') and ('Gene_Product_Has_Biochemical_Function' some 'Scaffolding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Protein Interaction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Receptor Signaling') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Subcellular Protein Targeting') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Reproductive Process') and ('Gene_Product_Encoded_By_Gene' some 'AKAP4 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142995</classIRI>
<classLabel>AKAP4 wt Allele</classLabel>
<newAxiom>'AKAP4 wt Allele' SubClassOf 'AKAP4 Gene'</newAxiom>
<newAxiom>'AKAP4 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some 'Xp11.22'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142994</classIRI>
<classLabel>AKAP4 Gene</classLabel>
<newAxiom>'AKAP4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Reproductive Process'</newAxiom>
<newAxiom>'AKAP4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Subcellular Protein Targeting'</newAxiom>
<newAxiom>'AKAP4 Gene' SubClassOf 'Adaptor Signaling Protein Gene'</newAxiom>
<newAxiom>'AKAP4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein-Protein Interaction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142993</classIRI>
<classLabel>Vabicaserin Hydrochloride</classLabel>
<newAxiom>'Vabicaserin Hydrochloride' SubClassOf 'Serotonin Agonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142992</classIRI>
<classLabel>Sperm Surface Protein Sp17</classLabel>
<newAxiom>'Sperm Surface Protein Sp17' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Spermatozoon'</newAxiom>
<newAxiom>'Sperm Surface Protein Sp17' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Fertilization'</newAxiom>
<newAxiom>'Sperm Surface Protein Sp17' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Cell Surface'</newAxiom>
<newAxiom>'Sperm Surface Protein Sp17' SubClassOf 'Gene_Product_Expressed_In_Tissue' some 'Testis'</newAxiom>
<newAxiom>'Sperm Surface Protein Sp17' SubClassOf 'Ligand Binding Protein'</newAxiom>
<newAxiom>'Sperm Surface Protein Sp17' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Carbohydrate Interaction'</newAxiom>
<newAxiom>'Sperm Surface Protein Sp17' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'SPA17 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142991</classIRI>
<classLabel>SPA17 wt Allele</classLabel>
<newAxiom>'SPA17 wt Allele' SubClassOf 'SPA17 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142990</classIRI>
<classLabel>SPA17 Gene</classLabel>
<newAxiom>'SPA17 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Fertilization'</newAxiom>
<newAxiom>'SPA17 Gene' SubClassOf 'Ligand Binding Protein Gene'</newAxiom>
<newAxiom>'SPA17 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein-Carbohydrate Interaction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142999</classIRI>
<classLabel>Tasidotin Hydrochloride</classLabel>
<newAxiom>'Tasidotin Hydrochloride' SubClassOf 'Tubulin Binding Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142998</classIRI>
<classLabel>Triciribine</classLabel>
<newAxiom>'Triciribine' SubClassOf 'Purine Antagonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142997</classIRI>
<classLabel>Tubocurarine Chloride Anhydrous</classLabel>
<newAxiom>'Tubocurarine Chloride Anhydrous' SubClassOf 'Muscle Relaxant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142985</classIRI>
<classLabel>Autologous Transplantation</classLabel>
<newAxiom>'Autologous Transplantation' SubClassOf 'Transplantation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142984</classIRI>
<classLabel>Polychemotherapy</classLabel>
<newAxiom>'Polychemotherapy' SubClassOf 'Chemotherapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142983</classIRI>
<classLabel>Refractory Thyroid Gland Carcinoma</classLabel>
<newAxiom>'Refractory Thyroid Gland Carcinoma' EquivalentTo 'Thyroid Gland Carcinoma' and 'Refractory Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142982</classIRI>
<classLabel>Refractory Lymphocyte-Rich Classical Hodgkin Lymphoma</classLabel>
<newAxiom>'Refractory Lymphocyte-Rich Classical Hodgkin Lymphoma' EquivalentTo 'Refractory Classical Hodgkin Lymphoma' and 'Lymphocyte-Rich Classical Hodgkin Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142981</classIRI>
<classLabel>Zoptarelin Doxorubicin Acetate</classLabel>
<newAxiom>'Zoptarelin Doxorubicin Acetate' SubClassOf 'Doxorubicin Preparation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142980</classIRI>
<classLabel>Selective Estrogen Receptor Covalent Antagonist H3B-6545</classLabel>
<newAxiom>'Selective Estrogen Receptor Covalent Antagonist H3B-6545' SubClassOf 'Antiestrogen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142988</classIRI>
<classLabel>Limited</classLabel>
<newAxiom>'Limited' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142987</classIRI>
<classLabel>Number of Metastases</classLabel>
<newAxiom>'Number of Metastases' SubClassOf 'Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142952</classIRI>
<classLabel>Bevantolol Hydrochloride</classLabel>
<newAxiom>'Bevantolol Hydrochloride' SubClassOf 'Beta-Adrenergic Antagonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142951</classIRI>
<classLabel>Benzhydrocodone Hydrochloride</classLabel>
<newAxiom>'Benzhydrocodone Hydrochloride' SubClassOf 'Opioid Receptor Agonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142950</classIRI>
<classLabel>Bentoquatam</classLabel>
<newAxiom>'Bentoquatam' SubClassOf 'Agent Affecting Integumentary System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142959</classIRI>
<classLabel>Bisacodyl Tannex</classLabel>
<newAxiom>'Bisacodyl Tannex' SubClassOf 'Agent Affecting Digestive System or Metabolism'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142958</classIRI>
<classLabel>Birtamimab</classLabel>
<newAxiom>'Birtamimab' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142957</classIRI>
<classLabel>Bipenamol Hydrochloride</classLabel>
<newAxiom>'Bipenamol Hydrochloride' SubClassOf 'Antidepressant Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142956</classIRI>
<classLabel>Bifeprunox Mesylate</classLabel>
<newAxiom>'Bifeprunox Mesylate' SubClassOf 'Antipsychotic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142955</classIRI>
<classLabel>Bictegravir Sodium</classLabel>
<newAxiom>'Bictegravir Sodium' SubClassOf 'Anti-HIV Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142954</classIRI>
<classLabel>Biclodil Hydrochloride</classLabel>
<newAxiom>'Biclodil Hydrochloride' SubClassOf 'Vasodilating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142953</classIRI>
<classLabel>Bevasiranib Sodium</classLabel>
<newAxiom>'Bevasiranib Sodium' SubClassOf 'Antisense RNA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142941</classIRI>
<classLabel>Avatrombopag Maleate</classLabel>
<newAxiom>'Avatrombopag Maleate' SubClassOf 'Agent Affecting Blood or Body Fluid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142940</classIRI>
<classLabel>Avacincaptad Pegol Sodium</classLabel>
<newAxiom>'Avacincaptad Pegol Sodium' SubClassOf 'Agent Affecting Organs of Special Senses'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142949</classIRI>
<classLabel>Bedaquiline Fumarate</classLabel>
<newAxiom>'Bedaquiline Fumarate' SubClassOf 'Antitubercular Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142948</classIRI>
<classLabel>Beclabuvir Hydrochloride</classLabel>
<newAxiom>'Beclabuvir Hydrochloride' SubClassOf 'Antiviral Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142947</classIRI>
<classLabel>Bavisant Dihydrochloride</classLabel>
<newAxiom>'Bavisant Dihydrochloride' SubClassOf 'CNS Stimulant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142946</classIRI>
<classLabel>Batefenterol Succinate</classLabel>
<newAxiom>'Batefenterol Succinate' SubClassOf 'Adrenergic Agonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142945</classIRI>
<classLabel>Azficel-T</classLabel>
<newAxiom>'Azficel-T' SubClassOf 'Biological Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142944</classIRI>
<classLabel>Azarole</classLabel>
<newAxiom>'Azarole' SubClassOf 'Immunotherapeutic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142943</classIRI>
<classLabel>Axelopran Sulfate</classLabel>
<newAxiom>'Axelopran Sulfate' SubClassOf 'Opiate Antagonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142942</classIRI>
<classLabel>Avibactam Sodium</classLabel>
<newAxiom>'Avibactam Sodium' SubClassOf 'Antibiotic'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142974</classIRI>
<classLabel>Butacetin</classLabel>
<newAxiom>'Butacetin' SubClassOf 'Analgesic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142973</classIRI>
<classLabel>Buparlisib Hydrochloride</classLabel>
<newAxiom>'Buparlisib Hydrochloride' SubClassOf 'Protein Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142972</classIRI>
<classLabel>Bunolol Hydrochloride</classLabel>
<newAxiom>'Bunolol Hydrochloride' SubClassOf 'Beta-Adrenergic Antagonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142971</classIRI>
<classLabel>Bucindolol Hydrochloride</classLabel>
<newAxiom>'Bucindolol Hydrochloride' SubClassOf 'Beta-Adrenergic Antagonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142970</classIRI>
<classLabel>Bucainide Maleate</classLabel>
<newAxiom>'Bucainide Maleate' SubClassOf 'Antiarrhythmic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142979</classIRI>
<classLabel>Insulin Degludec</classLabel>
<newAxiom>'Insulin Degludec' SubClassOf 'Therapeutic Insulin'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142978</classIRI>
<classLabel>Anti-LAG3 Monoclonal Antibody TSR-033</classLabel>
<newAxiom>'Anti-LAG3 Monoclonal Antibody TSR-033' SubClassOf 'Anti-LAG-3 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142977</classIRI>
<classLabel>Butirosin Sulfate</classLabel>
<newAxiom>'Butirosin Sulfate' SubClassOf 'Aminoglycoside Antibiotic'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142976</classIRI>
<classLabel>Butamirate Citrate</classLabel>
<newAxiom>'Butamirate Citrate' SubClassOf 'Antitussive Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142975</classIRI>
<classLabel>Butamben Picrate</classLabel>
<newAxiom>'Butamben Picrate' SubClassOf 'Anesthetic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142963</classIRI>
<classLabel>Bivalirudin Trifluoroacetate</classLabel>
<newAxiom>'Bivalirudin Trifluoroacetate' SubClassOf 'Anticoagulant Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142962</classIRI>
<classLabel>Bispyrithione Magsulfex</classLabel>
<newAxiom>'Bispyrithione Magsulfex' SubClassOf 'Anti-Infective Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142961</classIRI>
<classLabel>Bisoxatin Acetate</classLabel>
<newAxiom>'Bisoxatin Acetate' SubClassOf '3-Aminobenzo[a]pyrene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142960</classIRI>
<classLabel>Bisobrin Lactate</classLabel>
<newAxiom>'Bisobrin Lactate' SubClassOf 'Hemostatic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142969</classIRI>
<classLabel>Bromperidol Decanoate</classLabel>
<newAxiom>'Bromperidol Decanoate' SubClassOf 'Antipsychotic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142968</classIRI>
<classLabel>Bromhexine Hydrochloride</classLabel>
<newAxiom>'Bromhexine Hydrochloride' SubClassOf 'Mucolytic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142967</classIRI>
<classLabel>Brivoligide Sodium</classLabel>
<newAxiom>'Brivoligide Sodium' SubClassOf 'Analgesic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142966</classIRI>
<classLabel>Brilacidin Tetrahydrochloride</classLabel>
<newAxiom>'Brilacidin Tetrahydrochloride' SubClassOf 'Antibiotic'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142965</classIRI>
<classLabel>Bradanicline Hydrochloride</classLabel>
<newAxiom>'Bradanicline Hydrochloride' SubClassOf 'Nicotinic Agonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142964</classIRI>
<classLabel>Bornyl Acetate</classLabel>
<newAxiom>'Bornyl Acetate' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142875</classIRI>
<classLabel>Short Course Chemoradiotherapy</classLabel>
<newAxiom>'Short Course Chemoradiotherapy' SubClassOf 'Chemoradiotherapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142874</classIRI>
<classLabel>Long Course Chemoradiotherapy</classLabel>
<newAxiom>'Long Course Chemoradiotherapy' SubClassOf 'Chemoradiotherapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142879</classIRI>
<classLabel>KRAS Gene Mutation Negative</classLabel>
<newAxiom>'KRAS Gene Mutation Negative' SubClassOf 'Negative Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142878</classIRI>
<classLabel>ROS1 Gene Amplification</classLabel>
<newAxiom>'ROS1 Gene Amplification' SubClassOf 'Gene Amplification Abnormality'</newAxiom>
<newAxiom>'ROS1 Gene Amplification' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'ROS1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142877</classIRI>
<classLabel>Refractory Primary Cutaneous Lymphoma</classLabel>
<newAxiom>'Refractory Primary Cutaneous Lymphoma' EquivalentTo 'Refractory Lymphoma' and 'Primary Cutaneous Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142876</classIRI>
<classLabel>Recurrent Primary Cutaneous Lymphoma</classLabel>
<newAxiom>'Recurrent Primary Cutaneous Lymphoma' EquivalentTo 'Recurrent Primary Malignant Neoplasm' and 'Recurrent Lymphoma' and 'Primary Cutaneous Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142897</classIRI>
<classLabel>Abexinostat Hydrochloride</classLabel>
<newAxiom>'Abexinostat Hydrochloride' SubClassOf 'Histone Deacetylase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142896</classIRI>
<classLabel>Abediterol Napadisylate</classLabel>
<newAxiom>'Abediterol Napadisylate' SubClassOf 'Beta-Adrenergic Agonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142895</classIRI>
<classLabel>Abafilcon A</classLabel>
<newAxiom>'Abafilcon A' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142894</classIRI>
<classLabel>Long QT Syndrome 8</classLabel>
<newAxiom>'Long QT Syndrome 8' SubClassOf 'Long QT Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142893</classIRI>
<classLabel>Spastic Paraplegia 3A</classLabel>
<newAxiom>'Spastic Paraplegia 3A' SubClassOf 'Hereditary Spastic Paraplegia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142892</classIRI>
<classLabel>Familial Hypertrophic Cardiomyopathy Type 2</classLabel>
<newAxiom>'Familial Hypertrophic Cardiomyopathy Type 2' SubClassOf 'Familial Hypertrophic Cardiomyopathy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142891</classIRI>
<classLabel>Brugada Syndrome</classLabel>
<newAxiom>'Brugada Syndrome' SubClassOf 'Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142890</classIRI>
<classLabel>Anti-HER2 Monoclonal Antibody/Anti-CD137Anticalin Bispecific Fusion Protein PRS-343</classLabel>
<newAxiom>'Anti-HER2 Monoclonal Antibody/Anti-CD137Anticalin Bispecific Fusion Protein PRS-343' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142899</classIRI>
<classLabel>Adomiparin</classLabel>
<newAxiom>'Adomiparin' SubClassOf 'Low Molecular Weight Heparin'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142898</classIRI>
<classLabel>Acorafloxacin Hydrochloride</classLabel>
<newAxiom>'Acorafloxacin Hydrochloride' SubClassOf 'Fluoroquinolone Antibiotic'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142886</classIRI>
<classLabel>Hydrosalpinx</classLabel>
<newAxiom>'Hydrosalpinx' SubClassOf 'Female Reproductive System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142885</classIRI>
<classLabel>Post-Abortion Endometritis</classLabel>
<newAxiom>'Post-Abortion Endometritis' SubClassOf 'Endometritis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142884</classIRI>
<classLabel>Friability</classLabel>
<newAxiom>'Friability' SubClassOf 'Other Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142882</classIRI>
<classLabel>Recurrent Hairy Cell Leukemia</classLabel>
<newAxiom>'Recurrent Hairy Cell Leukemia' EquivalentTo 'Recurrent Hematologic Malignancy' and 'Hairy Cell Leukemia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142881</classIRI>
<classLabel>Recurrent Alveolar Rhabdomyosarcoma</classLabel>
<newAxiom>'Recurrent Alveolar Rhabdomyosarcoma' EquivalentTo 'Alveolar Rhabdomyosarcoma' and 'Recurrent Rhabdomyosarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142880</classIRI>
<classLabel>Refractory Alveolar Rhabdomyosarcoma</classLabel>
<newAxiom>'Refractory Alveolar Rhabdomyosarcoma' EquivalentTo 'Refractory Rhabdomyosarcoma' and 'Alveolar Rhabdomyosarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142889</classIRI>
<classLabel>Anti-HER2/Anti-CD3 Bispecific Monoclonal Antibody GBR 1302</classLabel>
<newAxiom>'Anti-HER2/Anti-CD3 Bispecific Monoclonal Antibody GBR 1302' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-HER2/Anti-CD3 Bispecific Monoclonal Antibody GBR 1302' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142888</classIRI>
<classLabel>Anti-K-RAS G12V mTCR-transduced Autologous Peripheral Blood Lymphocytes</classLabel>
<newAxiom>'Anti-K-RAS G12V mTCR-transduced Autologous Peripheral Blood Lymphocytes' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Anti-K-RAS G12V mTCR-transduced Autologous Peripheral Blood Lymphocytes' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Anti-K-RAS G12V mTCR-transduced Autologous Peripheral Blood Lymphocytes' SubClassOf 'T-cell Receptor-engineered T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142887</classIRI>
<classLabel>Autologous Anti-CD19 Chimeric Antigen Receptor T-cells SJCAR19</classLabel>
<newAxiom>'Autologous Anti-CD19 Chimeric Antigen Receptor T-cells SJCAR19' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous Anti-CD19 Chimeric Antigen Receptor T-cells SJCAR19' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Autologous Anti-CD19 Chimeric Antigen Receptor T-cells SJCAR19' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>