<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
825
</numberChangedClasses>
<numberNewClasses>
429
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C119703</classIRI>
<classLabel>Autologous 4-1BB Selected Tumor Infiltrating Lymphocytes</classLabel>
<deletedAxiom>&apos;Autologous 4-1BB Selected Tumor Infiltrating Lymphocytes&apos; SubClassOf &apos;Therapeutic Tumor Infiltrating Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Autologous 4-1BB Selected Tumor Infiltrating Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
<newAxiom>&apos;Autologous 4-1BB Selected Tumor Infiltrating Lymphocytes&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178284</classIRI>
<classLabel>Anti-EGFR/CD28 Bispecific Antibody REGN7075</classLabel>
<deletedAxiom>&apos;Anti-EGFR/CD28 Bispecific Antibody REGN7075&apos; SubClassOf &apos;EGFR-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-EGFR/CD28 Bispecific Antibody REGN7075&apos; SubClassOf &apos;Anti-EGFR Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C130050</classIRI>
<classLabel>Plamotamab</classLabel>
<deletedAxiom>&apos;Plamotamab&apos; SubClassOf &apos;Anti-CD20 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Plamotamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Plamotamab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Plamotamab&apos; SubClassOf &apos;Anti-CD20/Anti-CD3 Bispecific Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C119615</classIRI>
<classLabel>Odronextamab</classLabel>
<deletedAxiom>&apos;Odronextamab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Odronextamab&apos; SubClassOf &apos;Anti-CD20 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Odronextamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Odronextamab&apos; SubClassOf &apos;Anti-CD20/Anti-CD3 Bispecific Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28699</classIRI>
<classLabel>Therapeutic Tumor Infiltrating Lymphocytes</classLabel>
<deletedAxiom>&apos;Therapeutic Tumor Infiltrating Lymphocytes&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Therapeutic Tumor Infiltrating Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28786</classIRI>
<classLabel>3H1 Aluminum Hydroxide-Precipitated Anti-Idiotype Monoclonal Antibody</classLabel>
<newAxiom>&apos;3H1 Aluminum Hydroxide-Precipitated Anti-Idiotype Monoclonal Antibody&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28976</classIRI>
<classLabel>Dendritic Cell Therapy</classLabel>
<deletedAxiom>&apos;Dendritic Cell Therapy&apos; SubClassOf &apos;Cellular Therapy&apos;</deletedAxiom>
<deletedAxiom>&apos;Dendritic Cell Therapy&apos; SubClassOf &apos;Biological Cancer Immunotherapy&apos;</deletedAxiom>
<newAxiom>&apos;Dendritic Cell Therapy&apos; SubClassOf &apos;Adoptive Immunotherapy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158531</classIRI>
<classLabel>Immunodeficiency with Hyper-IgM, X-Linked, Type 1</classLabel>
<deletedAxiom>&apos;Immunodeficiency with Hyper-IgM, X-Linked, Type 1&apos; SubClassOf &apos;Hyperimmunoglobulin M Syndrome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158513</classIRI>
<classLabel>Anti-c-Met Antibody-drug Conjugate TR1801</classLabel>
<deletedAxiom>&apos;Anti-c-Met Antibody-drug Conjugate TR1801&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-c-Met Antibody-drug Conjugate TR1801&apos; SubClassOf &apos;c-Met-targeting Agent&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-c-Met Antibody-drug Conjugate TR1801&apos; SubClassOf &apos;Immunoconjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-c-Met Antibody-drug Conjugate TR1801&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201552</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87453</classIRI>
<classLabel>Rimabotulinumtoxinb</classLabel>
<deletedAxiom>&apos;Rimabotulinumtoxinb&apos; SubClassOf &apos;Bacterial Toxin&apos;</deletedAxiom>
<newAxiom>&apos;Rimabotulinumtoxinb&apos; SubClassOf &apos;Botulinum Toxin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3680</classIRI>
<classLabel>Cribriform Carcinoma</classLabel>
<deletedAxiom>&apos;Cribriform Carcinoma&apos; EquivalentTo &apos;Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Cribriform Pattern&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Papillary Growth Pattern&apos;)</deletedAxiom>
<newAxiom>&apos;Cribriform Carcinoma&apos; EquivalentTo &apos;Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Cribriform Pattern&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Papillary Growth Pattern&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Comedo Necrosis&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158682</classIRI>
<classLabel>Autologous Anti-GD2CAR-CD28-CD3zeta-IL-15-expressing Natural Killer T-cells</classLabel>
<newAxiom>&apos;Autologous Anti-GD2CAR-CD28-CD3zeta-IL-15-expressing Natural Killer T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201491</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3689</classIRI>
<classLabel>Appendix Goblet Cell Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Appendix Goblet Cell Adenocarcinoma&apos; EquivalentTo &apos;Combined Carcinoid and Adenocarcinoma&apos; and &apos;Appendix Mixed Adenoneuroendocrine Carcinoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Signet Ring Adenocarcinoma Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Chromogranin-A Positive Neoplastic Cells Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Serotonin-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Somatostatin-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Submucosal Tumor Growth&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;)</deletedAxiom>
<newAxiom>&apos;Appendix Goblet Cell Adenocarcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201135 and &apos;Appendix Neuroendocrine Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Chromogranin-A Positive Neoplastic Cells Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Serotonin-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Somatostatin-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Submucosal Tumor Growth&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158606</classIRI>
<classLabel>CRISPR-Cas9-mediated PD-1 and TCR Gene-deleted Anti-mesothelin CAR T-cells</classLabel>
<deletedAxiom>&apos;CRISPR-Cas9-mediated PD-1 and TCR Gene-deleted Anti-mesothelin CAR T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;CRISPR-Cas9-mediated PD-1 and TCR Gene-deleted Anti-mesothelin CAR T-cells&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<deletedAxiom>&apos;CRISPR-Cas9-mediated PD-1 and TCR Gene-deleted Anti-mesothelin CAR T-cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;CRISPR-Cas9-mediated PD-1 and TCR Gene-deleted Anti-mesothelin CAR T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201275</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158602</classIRI>
<classLabel>Anti-EGFR CAR-transduced IL-12-expressing T-lymphocytes</classLabel>
<deletedAxiom>&apos;Anti-EGFR CAR-transduced IL-12-expressing T-lymphocytes&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-EGFR CAR-transduced IL-12-expressing T-lymphocytes&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-EGFR CAR-transduced IL-12-expressing T-lymphocytes&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anti-EGFR CAR-transduced IL-12-expressing T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201175</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C183539</classIRI>
<classLabel>FOXP3-Expressing Regulatory T-Lymphocyte Count Percent Change From Baseline</classLabel>
<deletedAxiom>&apos;FOXP3-Expressing Regulatory T-Lymphocyte Count Percent Change From Baseline&apos; SubClassOf &apos;T-Lymphocyte Count&apos;</deletedAxiom>
<newAxiom>&apos;FOXP3-Expressing Regulatory T-Lymphocyte Count Percent Change From Baseline&apos; SubClassOf &apos;Regulatory T-Lymphocyte Count&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C183511</classIRI>
<classLabel>Allogeneic Anti-CD70-CAR-IL-15-transduced Cord Blood-derived Natural Killer Cells</classLabel>
<deletedAxiom>&apos;Allogeneic Anti-CD70-CAR-IL-15-transduced Cord Blood-derived Natural Killer Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic Anti-CD70-CAR-IL-15-transduced Cord Blood-derived Natural Killer Cells&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</newAxiom>
<newAxiom>&apos;Allogeneic Anti-CD70-CAR-IL-15-transduced Cord Blood-derived Natural Killer Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124993</classIRI>
<classLabel>Amivantamab</classLabel>
<newAxiom>&apos;Amivantamab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158436</classIRI>
<classLabel>Nivatrotamab</classLabel>
<deletedAxiom>&apos;Nivatrotamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Nivatrotamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158438</classIRI>
<classLabel>iPSC-derived Natural Killer Cells FT500</classLabel>
<deletedAxiom>&apos;iPSC-derived Natural Killer Cells FT500&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;iPSC-derived Natural Killer Cells FT500&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87848</classIRI>
<classLabel>Clinical Events End Relative to Reference Time Point</classLabel>
<deletedAxiom>&apos;Clinical Events End Relative to Reference Time Point&apos; SubClassOf &apos;End Relative to Reference Period&apos;</deletedAxiom>
<newAxiom>&apos;Clinical Events End Relative to Reference Time Point&apos; SubClassOf &apos;End Relative to Reference Time Point&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87838</classIRI>
<classLabel>Adverse Event End Relative to Reference Time Point</classLabel>
<deletedAxiom>&apos;Adverse Event End Relative to Reference Time Point&apos; SubClassOf &apos;End Relative to Reference Period&apos;</deletedAxiom>
<newAxiom>&apos;Adverse Event End Relative to Reference Time Point&apos; SubClassOf &apos;End Relative to Reference Time Point&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87895</classIRI>
<classLabel>Medical History End Relative to Reference Time Point</classLabel>
<deletedAxiom>&apos;Medical History End Relative to Reference Time Point&apos; SubClassOf &apos;End Relative to Reference Period&apos;</deletedAxiom>
<newAxiom>&apos;Medical History End Relative to Reference Time Point&apos; SubClassOf &apos;End Relative to Reference Time Point&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158087</classIRI>
<classLabel>Anti-CD38/BCMA CAR T-lymphocytes</classLabel>
<deletedAxiom>&apos;Anti-CD38/BCMA CAR T-lymphocytes&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD38/BCMA CAR T-lymphocytes&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD38/BCMA CAR T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201510</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87862</classIRI>
<classLabel>Concomitant Medication End Relative to Reference Time Point</classLabel>
<deletedAxiom>&apos;Concomitant Medication End Relative to Reference Time Point&apos; SubClassOf &apos;End Relative to Reference Period&apos;</deletedAxiom>
<newAxiom>&apos;Concomitant Medication End Relative to Reference Time Point&apos; SubClassOf &apos;End Relative to Reference Time Point&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C183159</classIRI>
<classLabel>Anti-CCR8 Monoclonal Antibody GS-1811</classLabel>
<newAxiom>&apos;Anti-CCR8 Monoclonal Antibody GS-1811&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C183133</classIRI>
<classLabel>CD19x22 Bicistronic CAR T-cells</classLabel>
<deletedAxiom>&apos;CD19x22 Bicistronic CAR T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;CD19x22 Bicistronic CAR T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201173</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48408</classIRI>
<classLabel>Monoclonal Antibody HuPAM4</classLabel>
<deletedAxiom>&apos;Monoclonal Antibody HuPAM4&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Monoclonal Antibody HuPAM4&apos; SubClassOf &apos;Anti-MUC-1 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48426</classIRI>
<classLabel>Volociximab</classLabel>
<newAxiom>&apos;Volociximab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124656</classIRI>
<classLabel>Anti-CD22 scFv TCRz:41BB-CAR Lentiviral Vector-transduced Autologous T-lymphocytes</classLabel>
<newAxiom>&apos;Anti-CD22 scFv TCRz:41BB-CAR Lentiviral Vector-transduced Autologous T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201173</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73555</classIRI>
<classLabel>ABCB5 Gene</classLabel>
<newAxiom>&apos;ABCB5 Gene&apos; SubClassOf &apos;Translocase Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73557</classIRI>
<classLabel>ATP-Binding Cassette Sub-Family B Member 5</classLabel>
<deletedAxiom>&apos;ATP-Binding Cassette Sub-Family B Member 5&apos; EquivalentTo &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Multidrug Resistance Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Drug Efflux&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transmembrane Transport&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ABCB5 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;ATP-Binding Cassette Sub-Family B Member 5&apos; EquivalentTo &apos;Translocase&apos; and &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Multidrug Resistance Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Drug Efflux&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transmembrane Transport&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ABCB5 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150518</classIRI>
<classLabel>Autologous Anti-EGFRvIII 4SCAR-IgT Cells</classLabel>
<newAxiom>&apos;Autologous Anti-EGFRvIII 4SCAR-IgT Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201175</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125548</classIRI>
<classLabel>Emactuzumab</classLabel>
<deletedAxiom>&apos;Emactuzumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Emactuzumab&apos; SubClassOf &apos;Anti-CSF1R Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150590</classIRI>
<classLabel>Serclutamab Talirine</classLabel>
<deletedAxiom>&apos;Serclutamab Talirine&apos; SubClassOf &apos;EGFR-targeting Agent&apos;</deletedAxiom>
<deletedAxiom>&apos;Serclutamab Talirine&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Serclutamab Talirine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201551</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198695</classIRI>
<classLabel>Anti-CCR8 Monoclonal Antibody SRF114</classLabel>
<newAxiom>&apos;Anti-CCR8 Monoclonal Antibody SRF114&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150682</classIRI>
<classLabel>Autologous Mesothelin-specific CAR-T-Cells Expressing Anti-PD-1/CTLA-4 Antibodies</classLabel>
<newAxiom>&apos;Autologous Mesothelin-specific CAR-T-Cells Expressing Anti-PD-1/CTLA-4 Antibodies&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201275</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150699</classIRI>
<classLabel>Autologous PSMA-4SCAR-expressing T-cells 4SCAR-PSMA</classLabel>
<newAxiom>&apos;Autologous PSMA-4SCAR-expressing T-cells 4SCAR-PSMA&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201178</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48814</classIRI>
<classLabel>Melanoma Tumor-Reactive Autologous Tumor Infiltrating Lymphocyte</classLabel>
<deletedAxiom>&apos;Melanoma Tumor-Reactive Autologous Tumor Infiltrating Lymphocyte&apos; SubClassOf &apos;Therapeutic Tumor Infiltrating Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Melanoma Tumor-Reactive Autologous Tumor Infiltrating Lymphocyte&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
<newAxiom>&apos;Melanoma Tumor-Reactive Autologous Tumor Infiltrating Lymphocyte&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48817</classIRI>
<classLabel>Renal Tumor-Reactive Autologous Tumor Infiltrating Lymphocyte</classLabel>
<deletedAxiom>&apos;Renal Tumor-Reactive Autologous Tumor Infiltrating Lymphocyte&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Renal Tumor-Reactive Autologous Tumor Infiltrating Lymphocyte&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125420</classIRI>
<classLabel>Allogeneic CD123CAR-CD28-CD3zeta-EGFRt-expressing T-lymphocytes</classLabel>
<newAxiom>&apos;Allogeneic CD123CAR-CD28-CD3zeta-EGFRt-expressing T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201493</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150483</classIRI>
<classLabel>Cord Blood-derived Expanded Allogeneic Natural Killer Cells</classLabel>
<deletedAxiom>&apos;Cord Blood-derived Expanded Allogeneic Natural Killer Cells&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<deletedAxiom>&apos;Cord Blood-derived Expanded Allogeneic Natural Killer Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Cord Blood-derived Expanded Allogeneic Natural Killer Cells&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</newAxiom>
<newAxiom>&apos;Cord Blood-derived Expanded Allogeneic Natural Killer Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34434</classIRI>
<classLabel>Bonnevie-Ullrich Syndrome</classLabel>
<newAxiom>&apos;Bonnevie-Ullrich Syndrome&apos; SubClassOf &apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Monosomy X&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125101</classIRI>
<classLabel>Autologous Anti-CD123 CAR TCR/4-1BB-expressing T-lymphocytes</classLabel>
<newAxiom>&apos;Autologous Anti-CD123 CAR TCR/4-1BB-expressing T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201493</newAxiom>
</changedClass>
<changedClass>
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<classLabel>EWSR1/ZNF444 Fusion Gene</classLabel>
<deletedAxiom>&apos;EWSR1/ZNF444 Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<newAxiom>&apos;EWSR1/ZNF444 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C139549</classIRI>
<classLabel>Cevostamab</classLabel>
<deletedAxiom>&apos;Cevostamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Cevostamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
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<classLabel>EWSR1/PBX1 Fusion Gene</classLabel>
<deletedAxiom>&apos;EWSR1/PBX1 Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<newAxiom>&apos;EWSR1/PBX1 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Histoplasma capsulatum</classLabel>
<deletedAxiom>&apos;Histoplasma capsulatum&apos; SubClassOf &apos;Ajellomyces capsulatus&apos;</deletedAxiom>
<newAxiom>&apos;Histoplasma capsulatum&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C130993</classIRI>
<classLabel>Kenny-Caffey Syndrome Type 2</classLabel>
<newAxiom>&apos;Kenny-Caffey Syndrome Type 2&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201155</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C164140</classIRI>
<classLabel>iPSC-derived CD16-expressing Natural Killer Cells FT516</classLabel>
<deletedAxiom>&apos;iPSC-derived CD16-expressing Natural Killer Cells FT516&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;iPSC-derived CD16-expressing Natural Killer Cells FT516&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178589</classIRI>
<classLabel>Anti-CD19/CD3 Bispecific Antibody GNR-084</classLabel>
<deletedAxiom>&apos;Anti-CD19/CD3 Bispecific Antibody GNR-084&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD19/CD3 Bispecific Antibody GNR-084&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD19/CD3 Bispecific Antibody GNR-084&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178575</classIRI>
<classLabel>BCMA-specific Universal CAR-expressing T-lymphocytes LCAR-BCX</classLabel>
<deletedAxiom>&apos;BCMA-specific Universal CAR-expressing T-lymphocytes LCAR-BCX&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<deletedAxiom>&apos;BCMA-specific Universal CAR-expressing T-lymphocytes LCAR-BCX&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;BCMA-specific Universal CAR-expressing T-lymphocytes LCAR-BCX&apos; SubClassOf &apos;Anti-BCMA-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178577</classIRI>
<classLabel>Anti-CD19/CD3 Bispecific Antibody TNB-486</classLabel>
<deletedAxiom>&apos;Anti-CD19/CD3 Bispecific Antibody TNB-486&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD19/CD3 Bispecific Antibody TNB-486&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD19/CD3 Bispecific Antibody TNB-486&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178569</classIRI>
<classLabel>Adenosine A2A Receptor Antagonist DZD2269</classLabel>
<deletedAxiom>&apos;Adenosine A2A Receptor Antagonist DZD2269&apos; SubClassOf &apos;Immunostimulant&apos;</deletedAxiom>
<newAxiom>&apos;Adenosine A2A Receptor Antagonist DZD2269&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201170</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29212</classIRI>
<classLabel>MoAb Bombesin (DTPA)</classLabel>
<deletedAxiom>&apos;MoAb Bombesin (DTPA)&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;MoAb Bombesin (DTPA)&apos; SubClassOf &apos;Immunoconjugate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29229</classIRI>
<classLabel>Monoclonal Antibody RG 83852</classLabel>
<deletedAxiom>&apos;Monoclonal Antibody RG 83852&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Monoclonal Antibody RG 83852&apos; SubClassOf &apos;Anti-EGFR Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178316</classIRI>
<classLabel>Autologous PD-1 Nanobody-expressing Anti-MSLN CAR T-cells</classLabel>
<newAxiom>&apos;Autologous PD-1 Nanobody-expressing Anti-MSLN CAR T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201275</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178335</classIRI>
<classLabel>Anti-Claudin18.2 CAR T Cells LCAR-C18S</classLabel>
<deletedAxiom>&apos;Anti-Claudin18.2 CAR T Cells LCAR-C18S&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-Claudin18.2 CAR T Cells LCAR-C18S&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anti-Claudin18.2 CAR T Cells LCAR-C18S&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201172</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178340</classIRI>
<classLabel>Autologous Anti-HER2 CAR T-cells CCT303-406</classLabel>
<newAxiom>&apos;Autologous Anti-HER2 CAR T-cells CCT303-406&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201497</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178327</classIRI>
<classLabel>Anti-EpCAM/Anti-CD3 Bispecific Antibody M701</classLabel>
<deletedAxiom>&apos;Anti-EpCAM/Anti-CD3 Bispecific Antibody M701&apos; SubClassOf &apos;Bispecific Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-EpCAM/Anti-CD3 Bispecific Antibody M701&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-EpCAM/Anti-CD3 Bispecific Antibody M701&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
<newAxiom>&apos;Anti-EpCAM/Anti-CD3 Bispecific Antibody M701&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
<newAxiom>&apos;Anti-EpCAM/Anti-CD3 Bispecific Antibody M701&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201523</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178328</classIRI>
<classLabel>Anti-HER2/Anti-CD3 Bispecific Antibody M802</classLabel>
<deletedAxiom>&apos;Anti-HER2/Anti-CD3 Bispecific Antibody M802&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-HER2/Anti-CD3 Bispecific Antibody M802&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-HER2/Anti-CD3 Bispecific Antibody M802&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178330</classIRI>
<classLabel>Autologous Natural Killer Cells SNK01</classLabel>
<deletedAxiom>&apos;Autologous Natural Killer Cells SNK01&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Natural Killer Cells SNK01&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
<newAxiom>&apos;Autologous Natural Killer Cells SNK01&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C119988</classIRI>
<classLabel>Genetically Engineered Hematopoietic Stem Progenitor Cells</classLabel>
<newAxiom>&apos;Genetically Engineered Hematopoietic Stem Progenitor Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20987</classIRI>
<classLabel>CTNNB1 Gene</classLabel>
<deletedAxiom>&apos;CTNNB1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Solid Pseudopapillary Neoplasm of the Pancreas&apos;</deletedAxiom>
<deletedAxiom>&apos;CTNNB1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Solid Pseudopapillary Neoplasm of the Ovary&apos;</deletedAxiom>
<newAxiom>&apos;CTNNB1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201136</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178439</classIRI>
<classLabel>Anti-MSLN CAR-T Cells LCAR-M23</classLabel>
<deletedAxiom>&apos;Anti-MSLN CAR-T Cells LCAR-M23&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-MSLN CAR-T Cells LCAR-M23&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anti-MSLN CAR-T Cells LCAR-M23&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201275</newAxiom>
</changedClass>
<changedClass>
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<classLabel>A2A/A2B Adenosine Receptor Antagonist INCB106385</classLabel>
<deletedAxiom>&apos;A2A/A2B Adenosine Receptor Antagonist INCB106385&apos; SubClassOf &apos;Immunostimulant&apos;</deletedAxiom>
<newAxiom>&apos;A2A/A2B Adenosine Receptor Antagonist INCB106385&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201170</newAxiom>
<newAxiom>&apos;A2A/A2B Adenosine Receptor Antagonist INCB106385&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201171</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Allogeneic CD20 CAR-grafted Gamma Delta T-cells ADI-001</classLabel>
<newAxiom>&apos;Allogeneic CD20 CAR-grafted Gamma Delta T-cells ADI-001&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178422</classIRI>
<classLabel>Talc Poudrage</classLabel>
<deletedAxiom>&apos;Talc Poudrage&apos; SubClassOf &apos;Therapeutic Thoracoscopic Surgery&apos;</deletedAxiom>
<newAxiom>&apos;Talc Poudrage&apos; SubClassOf &apos;Pleurodesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178410</classIRI>
<classLabel>Anti-PSMA Antibody-drug Conjugate ARX517</classLabel>
<deletedAxiom>&apos;Anti-PSMA Antibody-drug Conjugate ARX517&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA Antibody-drug Conjugate ARX517&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PSMA Antibody-drug Conjugate ARX517&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201544</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Universal Anti-CD7 CAR T Cells RD13-01</classLabel>
<deletedAxiom>&apos;Universal Anti-CD7 CAR T Cells RD13-01&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Universal Anti-CD7 CAR T Cells RD13-01&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Universal Anti-CD7 CAR T Cells RD13-01&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201177</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Anti-CD22/CD3 Bispecific Antibody JNJ-75348780</classLabel>
<deletedAxiom>&apos;Anti-CD22/CD3 Bispecific Antibody JNJ-75348780&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD22/CD3 Bispecific Antibody JNJ-75348780&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD22/CD3 Bispecific Antibody JNJ-75348780&apos; SubClassOf &apos;Anti-CD20 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD22/CD3 Bispecific Antibody JNJ-75348780&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Autologous Anti-PD-L1-armored Anti-CD22 CAR T Cells</classLabel>
<newAxiom>&apos;Autologous Anti-PD-L1-armored Anti-CD22 CAR T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201173</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178487</classIRI>
<classLabel>EWSR1/NFATC2 Fusion Gene</classLabel>
<deletedAxiom>&apos;EWSR1/NFATC2 Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<newAxiom>&apos;EWSR1/NFATC2 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178488</classIRI>
<classLabel>FUS/NFATC2 Fusion Gene</classLabel>
<deletedAxiom>&apos;FUS/NFATC2 Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<newAxiom>&apos;FUS/NFATC2 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178455</classIRI>
<classLabel>Allogeneic Natural Killer Cells PB103</classLabel>
<deletedAxiom>&apos;Allogeneic Natural Killer Cells PB103&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic Natural Killer Cells PB103&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29478</classIRI>
<classLabel>Tumor Infiltrating Lymphocytes-N2-Transduced</classLabel>
<deletedAxiom>&apos;Tumor Infiltrating Lymphocytes-N2-Transduced&apos; SubClassOf &apos;Therapeutic Tumor Infiltrating Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Tumor Infiltrating Lymphocytes-N2-Transduced&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29481</classIRI>
<classLabel>Monoclonal Antibody T101 F(ab)2</classLabel>
<deletedAxiom>&apos;Monoclonal Antibody T101 F(ab)2&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Monoclonal Antibody T101 F(ab)2&apos; SubClassOf &apos;Anti-CD5 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29482</classIRI>
<classLabel>TNF Transduced TIL</classLabel>
<newAxiom>&apos;TNF Transduced TIL&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118442</classIRI>
<classLabel>Anti-gpA33/CD3 Monoclonal Antibody MGD007</classLabel>
<deletedAxiom>&apos;Anti-gpA33/CD3 Monoclonal Antibody MGD007&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-gpA33/CD3 Monoclonal Antibody MGD007&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29511</classIRI>
<classLabel>TriGem</classLabel>
<newAxiom>&apos;TriGem&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118571</classIRI>
<classLabel>Telisotuzumab Vedotin</classLabel>
<deletedAxiom>&apos;Telisotuzumab Vedotin&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Telisotuzumab Vedotin&apos; SubClassOf &apos;c-Met-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Telisotuzumab Vedotin&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201552</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118284</classIRI>
<classLabel>Zilovertamab</classLabel>
<newAxiom>&apos;Zilovertamab&apos; SubClassOf &apos;ROR1-targeting Agent&apos;</newAxiom>
<newAxiom>&apos;Zilovertamab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88002</classIRI>
<classLabel>Substance Usage End Relative to Reference Time Point</classLabel>
<deletedAxiom>&apos;Substance Usage End Relative to Reference Time Point&apos; SubClassOf &apos;End Relative to Reference Period&apos;</deletedAxiom>
<newAxiom>&apos;Substance Usage End Relative to Reference Time Point&apos; SubClassOf &apos;End Relative to Reference Time Point&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2006</classIRI>
<classLabel>SGN-17/19</classLabel>
<deletedAxiom>&apos;SGN-17/19&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;SGN-17/19&apos; SubClassOf &apos;Immunoconjugate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2005</classIRI>
<classLabel>Monoclonal Antibody SGN-14</classLabel>
<deletedAxiom>&apos;Monoclonal Antibody SGN-14&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Monoclonal Antibody SGN-14&apos; SubClassOf &apos;Anti-CD40 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2012</classIRI>
<classLabel>Matuzumab</classLabel>
<deletedAxiom>&apos;Matuzumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Matuzumab&apos; SubClassOf &apos;Anti-EGFR Monoclonal Antibody&apos;</newAxiom>
<newAxiom>&apos;Matuzumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C182624</classIRI>
<classLabel>Autologous MGMTP140K Lentiviral Vector-transduced HSCs</classLabel>
<deletedAxiom>&apos;Autologous MGMTP140K Lentiviral Vector-transduced HSCs&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Autologous MGMTP140K Lentiviral Vector-transduced HSCs&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88311</classIRI>
<classLabel>Momelotinib</classLabel>
<newAxiom>&apos;Momelotinib&apos; SubClassOf &apos;ALK Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88315</classIRI>
<classLabel>Vorsetzumab Mafodotin</classLabel>
<deletedAxiom>&apos;Vorsetzumab Mafodotin&apos; SubClassOf &apos;CD70-targeting Agent&apos;</deletedAxiom>
<deletedAxiom>&apos;Vorsetzumab Mafodotin&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Vorsetzumab Mafodotin&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201550</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15351</classIRI>
<classLabel>Adoptive Immunotherapy</classLabel>
<deletedAxiom>&apos;Adoptive Immunotherapy&apos; SubClassOf &apos;Passive Immunization&apos;</deletedAxiom>
<newAxiom>&apos;Adoptive Immunotherapy&apos; SubClassOf &apos;Cellular Therapy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15412</classIRI>
<classLabel>Lymphokine-Activated Killer Cell Therapy</classLabel>
<deletedAxiom>&apos;Lymphokine-Activated Killer Cell Therapy&apos; SubClassOf &apos;Adoptive Immunotherapy&apos;</deletedAxiom>
<deletedAxiom>&apos;Lymphokine-Activated Killer Cell Therapy&apos; SubClassOf &apos;Cellular Therapy&apos;</deletedAxiom>
<newAxiom>&apos;Lymphokine-Activated Killer Cell Therapy&apos; SubClassOf &apos;Leukocyte Therapy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143156</classIRI>
<classLabel>Anti-CD19-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocytes</classLabel>
<newAxiom>&apos;Anti-CD19-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143157</classIRI>
<classLabel>Allogeneic Nicotinamide-expanded Natural Killer Cells</classLabel>
<deletedAxiom>&apos;Allogeneic Nicotinamide-expanded Natural Killer Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic Nicotinamide-expanded Natural Killer Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15545</classIRI>
<classLabel>Leukocyte Therapy</classLabel>
<deletedAxiom>&apos;Leukocyte Therapy&apos; SubClassOf &apos;Cellular Therapy&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157393</classIRI>
<classLabel>Autologous CD34-positive BCL11A-disrupted Hematopoietic Progenitor Cells BIVV003</classLabel>
<deletedAxiom>&apos;Autologous CD34-positive BCL11A-disrupted Hematopoietic Progenitor Cells BIVV003&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Autologous CD34-positive BCL11A-disrupted Hematopoietic Progenitor Cells BIVV003&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157370</classIRI>
<classLabel>TCR alpha/beta/CD19-depleted Allogeneic Hematopoietic Progenitor Cells</classLabel>
<deletedAxiom>&apos;TCR alpha/beta/CD19-depleted Allogeneic Hematopoietic Progenitor Cells&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;TCR alpha/beta/CD19-depleted Allogeneic Hematopoietic Progenitor Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74011</classIRI>
<classLabel>Dalotuzumab</classLabel>
<deletedAxiom>&apos;Dalotuzumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Dalotuzumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Dalotuzumab&apos; SubClassOf &apos;Anti-IGF1R Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88647</classIRI>
<classLabel>Teplizumab</classLabel>
<deletedAxiom>&apos;Teplizumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Teplizumab&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157488</classIRI>
<classLabel>EBV LMP-2A-specific Autologous CD8+ T-cells</classLabel>
<deletedAxiom>&apos;EBV LMP-2A-specific Autologous CD8+ T-cells&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;EBV LMP-2A-specific Autologous CD8+ T-cells&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157489</classIRI>
<classLabel>Adenosine A2A Receptor Antagonist/Phosphodiesterase 10A PBF-999</classLabel>
<deletedAxiom>&apos;Adenosine A2A Receptor Antagonist/Phosphodiesterase 10A PBF-999&apos; SubClassOf &apos;Immunostimulant&apos;</deletedAxiom>
<newAxiom>&apos;Adenosine A2A Receptor Antagonist/Phosphodiesterase 10A PBF-999&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201170</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15699</classIRI>
<classLabel>T-Cell Depletion Therapy</classLabel>
<deletedAxiom>&apos;T-Cell Depletion Therapy&apos; SubClassOf &apos;Immunosuppressive Therapy&apos;</deletedAxiom>
<newAxiom>&apos;T-Cell Depletion Therapy&apos; SubClassOf &apos;Lymphodepletion Therapy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88612</classIRI>
<classLabel>Ibalizumab</classLabel>
<deletedAxiom>&apos;Ibalizumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Ibalizumab&apos; SubClassOf &apos;Anti-CD4 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123859</classIRI>
<classLabel>ABCB11 Gene</classLabel>
<newAxiom>&apos;ABCB11 Gene&apos; SubClassOf &apos;Translocase Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123861</classIRI>
<classLabel>Bile Salt Export Pump</classLabel>
<deletedAxiom>&apos;Bile Salt Export Pump&apos; EquivalentTo &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Multi-Drug Resistance Factor Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Hepatic Tissue&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;ATP Hydrolysis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ABCB11 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Bile Salt Export Pump&apos; EquivalentTo &apos;Translocase&apos; and &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Multi-Drug Resistance Factor Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Hepatic Tissue&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;ATP Hydrolysis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ABCB11 Gene&apos;)</newAxiom>
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<changedClass>
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<classLabel>GD2-CAR-expressing Autologous T-lymphocytes</classLabel>
<newAxiom>&apos;GD2-CAR-expressing Autologous T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201491</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2476</classIRI>
<classLabel>Monoclonal Antibody muJ591</classLabel>
<deletedAxiom>&apos;Monoclonal Antibody muJ591&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Monoclonal Antibody muJ591&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201543</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C182132</classIRI>
<classLabel>Autologous Tumor Infiltrating Lymphocytes ITIL-168</classLabel>
<deletedAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes ITIL-168&apos; SubClassOf &apos;Therapeutic Tumor Infiltrating Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes ITIL-168&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
<newAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes ITIL-168&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157158</classIRI>
<classLabel>Tyrosine Hydroxylase Deficiency</classLabel>
<newAxiom>&apos;Tyrosine Hydroxylase Deficiency&apos; SubClassOf &apos;Dystonia&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123914</classIRI>
<classLabel>Oleclumab</classLabel>
<deletedAxiom>&apos;Oleclumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Oleclumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Oleclumab&apos; SubClassOf &apos;Anti-CD73 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157281</classIRI>
<classLabel>Autologous CLL1-CD33 Compound CAR T Cells</classLabel>
<newAxiom>&apos;Autologous CLL1-CD33 Compound CAR T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201495</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157257</classIRI>
<classLabel>Anti-CD123/CD3 Bispecific Antibody APVO436</classLabel>
<deletedAxiom>&apos;Anti-CD123/CD3 Bispecific Antibody APVO436&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD123/CD3 Bispecific Antibody APVO436&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD123/CD3 Bispecific Antibody APVO436&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
<newAxiom>&apos;Anti-CD123/CD3 Bispecific Antibody APVO436&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201511</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2229</classIRI>
<classLabel>Visilizumab</classLabel>
<deletedAxiom>&apos;Visilizumab&apos; EquivalentTo &apos;Monoclonal Antibody&apos; and (&apos;Chemical_Or_Drug_Has_Mechanism_Of_Action&apos; some &apos;Antigen Binding&apos;) and (&apos;Chemical_Or_Drug_Has_Physiologic_Effect&apos; some &apos;Positive Regulation of Apoptosis&apos;) and (&apos;Chemical_Or_Drug_Affects_Gene_Product&apos; some &apos;CD3 Complex&apos;) and (&apos;Chemical_Or_Drug_Affects_Cell_Type_Or_Tissue&apos; some &apos;T-Lymphocyte&apos;)</deletedAxiom>
<newAxiom>&apos;Visilizumab&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123724</classIRI>
<classLabel>Interferon Beta-secreting Mesenchymal Stem Cells</classLabel>
<newAxiom>&apos;Interferon Beta-secreting Mesenchymal Stem Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201556</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123720</classIRI>
<classLabel>Akt-1/2 Inhibitor-treated Tumor Infiltrating Lymphocytes</classLabel>
<deletedAxiom>&apos;Akt-1/2 Inhibitor-treated Tumor Infiltrating Lymphocytes&apos; SubClassOf &apos;Therapeutic Tumor Infiltrating Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Akt-1/2 Inhibitor-treated Tumor Infiltrating Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
<newAxiom>&apos;Akt-1/2 Inhibitor-treated Tumor Infiltrating Lymphocytes&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C182001</classIRI>
<classLabel>Autologous Tumor Killer Cells</classLabel>
<deletedAxiom>&apos;Autologous Tumor Killer Cells&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Tumor Killer Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C182002</classIRI>
<classLabel>CRISPR-Cas9 Engineered TGFbRII-deleted Anti-EGFR CAR T-cells</classLabel>
<deletedAxiom>&apos;CRISPR-Cas9 Engineered TGFbRII-deleted Anti-EGFR CAR T-cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<deletedAxiom>&apos;CRISPR-Cas9 Engineered TGFbRII-deleted Anti-EGFR CAR T-cells&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</deletedAxiom>
<deletedAxiom>&apos;CRISPR-Cas9 Engineered TGFbRII-deleted Anti-EGFR CAR T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;CRISPR-Cas9 Engineered TGFbRII-deleted Anti-EGFR CAR T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201175</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C182004</classIRI>
<classLabel>Anti-MET x MET Antibody Drug Conjugate REGN5093-M114</classLabel>
<deletedAxiom>&apos;Anti-MET x MET Antibody Drug Conjugate REGN5093-M114&apos; SubClassOf &apos;c-Met-targeting Agent&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-MET x MET Antibody Drug Conjugate REGN5093-M114&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-MET x MET Antibody Drug Conjugate REGN5093-M114&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201552</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C182072</classIRI>
<classLabel>Allogeneic Anti-CD7 CAR-T Cells WU-CART-007</classLabel>
<newAxiom>&apos;Allogeneic Anti-CD7 CAR-T Cells WU-CART-007&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201177</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Anti-HLA-G/CD3 Bispecific Antibody JNJ-78306358</classLabel>
<deletedAxiom>&apos;Anti-HLA-G/CD3 Bispecific Antibody JNJ-78306358&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-HLA-G/CD3 Bispecific Antibody JNJ-78306358&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
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<changedClass>
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<classLabel>Autosomal Recessive Torsion Dystonia 2</classLabel>
<newAxiom>&apos;Autosomal Recessive Torsion Dystonia 2&apos; SubClassOf &apos;Genetic Torsion Dystonia&apos;</newAxiom>
</changedClass>
<changedClass>
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<newAxiom>&apos;Naxitamab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
<newAxiom>&apos;Naxitamab&apos; SubClassOf &apos;Anti-GD2 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
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<newAxiom>&apos;Anti-CD123 Monoclonal Antibody KHK2823&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201511</newAxiom>
</changedClass>
<changedClass>
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<classLabel>CD4 Expressing T Cell Count</classLabel>
<deletedAxiom>&apos;CD4 Expressing T Cell Count&apos; SubClassOf &apos;T-Lymphocyte Count&apos;</deletedAxiom>
<newAxiom>&apos;CD4 Expressing T Cell Count&apos; SubClassOf &apos;Helper Regulatory T-Lymphocyte Count&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>CD8 Expressing T Cell Count</classLabel>
<deletedAxiom>&apos;CD8 Expressing T Cell Count&apos; SubClassOf &apos;T-Lymphocyte Count&apos;</deletedAxiom>
<newAxiom>&apos;CD8 Expressing T Cell Count&apos; SubClassOf &apos;Cytotoxic T-Lymphocyte Count&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123574</classIRI>
<classLabel>Clinical Complete Response</classLabel>
<deletedAxiom>&apos;Clinical Complete Response&apos; SubClassOf &apos;Disease Response&apos;</deletedAxiom>
<newAxiom>&apos;Clinical Complete Response&apos; SubClassOf &apos;Complete Remission&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123585</classIRI>
<classLabel>Hematologic Improvement-Erythroid Response</classLabel>
<deletedAxiom>&apos;Hematologic Improvement-Erythroid Response&apos; SubClassOf &apos;Disease Response&apos;</deletedAxiom>
<newAxiom>&apos;Hematologic Improvement-Erythroid Response&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201498</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123586</classIRI>
<classLabel>Hematologic Improvement-Neutrophil Response</classLabel>
<deletedAxiom>&apos;Hematologic Improvement-Neutrophil Response&apos; SubClassOf &apos;Disease Response&apos;</deletedAxiom>
<newAxiom>&apos;Hematologic Improvement-Neutrophil Response&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201498</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123587</classIRI>
<classLabel>Hematologic Improvement-Platelet Response</classLabel>
<deletedAxiom>&apos;Hematologic Improvement-Platelet Response&apos; SubClassOf &apos;Disease Response&apos;</deletedAxiom>
<newAxiom>&apos;Hematologic Improvement-Platelet Response&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201498</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2733</classIRI>
<classLabel>Nimotuzumab</classLabel>
<deletedAxiom>&apos;Nimotuzumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Nimotuzumab&apos; SubClassOf &apos;Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Nimotuzumab&apos; SubClassOf &apos;Anti-EGFR Monoclonal Antibody&apos;</newAxiom>
<newAxiom>&apos;Nimotuzumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74638</classIRI>
<classLabel>CD4 T Cell to Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;CD4 T Cell to Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;CD4 T Cell to Lymphocyte Ratio Measurement&apos; SubClassOf &apos;CD4 Cell to Lymphocyte Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74639</classIRI>
<classLabel>CD8 T Cell to Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;CD8 T Cell to Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;CD8 T Cell to Lymphocyte Ratio Measurement&apos; SubClassOf &apos;CD8 Cell to Lymphocyte Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74635</classIRI>
<classLabel>CD19 B Cell to Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;CD19 B Cell to Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;CD19 B Cell to Lymphocyte Ratio Measurement&apos; SubClassOf &apos;CD19 Cell to Lymphocyte Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74636</classIRI>
<classLabel>CD3 T Cell to Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;CD3 T Cell to Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;CD3 T Cell to Lymphocyte Ratio Measurement&apos; SubClassOf &apos;CD3 Cell to Lymphocyte Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74637</classIRI>
<classLabel>CD4 T Cell to CD8 T Cell Ratio Measurement</classLabel>
<deletedAxiom>&apos;CD4 T Cell to CD8 T Cell Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;CD4 T Cell to CD8 T Cell Ratio Measurement&apos; SubClassOf &apos;Helper T-Lymphocytes to Cytotoxic T-Lymphocytes Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137863</classIRI>
<classLabel>Allogeneic CD3- CD19- CD57+ NKG2C+ NK Cells FATE-NK100</classLabel>
<deletedAxiom>&apos;Allogeneic CD3- CD19- CD57+ NKG2C+ NK Cells FATE-NK100&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic CD3- CD19- CD57+ NKG2C+ NK Cells FATE-NK100&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
<newAxiom>&apos;Allogeneic CD3- CD19- CD57+ NKG2C+ NK Cells FATE-NK100&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2658</classIRI>
<classLabel>Ertumaxomab</classLabel>
<deletedAxiom>&apos;Ertumaxomab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Ertumaxomab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2652</classIRI>
<classLabel>Rosopatamab</classLabel>
<deletedAxiom>&apos;Rosopatamab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Rosopatamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201543</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162765</classIRI>
<classLabel>CD3+/CD19+ Cell-depleted Unrelated or Partially Matched Donor-derived Allogeneic Peripheral Blood Stem Cells</classLabel>
<deletedAxiom>&apos;CD3+/CD19+ Cell-depleted Unrelated or Partially Matched Donor-derived Allogeneic Peripheral Blood Stem Cells&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;CD3+/CD19+ Cell-depleted Unrelated or Partially Matched Donor-derived Allogeneic Peripheral Blood Stem Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201557</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162774</classIRI>
<classLabel>Iparomlimab/Tuvonralimab</classLabel>
<deletedAxiom>&apos;Iparomlimab/Tuvonralimab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35256</classIRI>
<classLabel>Aicardi Syndrome</classLabel>
<newAxiom>&apos;Aicardi Syndrome&apos; SubClassOf &apos;X-Linked Inherited Disorder&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162936</classIRI>
<classLabel>Nezastomig</classLabel>
<deletedAxiom>&apos;Nezastomig&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Nezastomig&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201543</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123332</classIRI>
<classLabel>Eluvixtamab</classLabel>
<deletedAxiom>&apos;Eluvixtamab&apos; SubClassOf &apos;Bispecific Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Eluvixtamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2534</classIRI>
<classLabel>Autologous Expanded Mesenchymal Stem Cells OTI-010</classLabel>
<deletedAxiom>&apos;Autologous Expanded Mesenchymal Stem Cells OTI-010&apos; SubClassOf &apos;Non-Tumor Cell Derivative Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Expanded Mesenchymal Stem Cells OTI-010&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201556</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2573</classIRI>
<classLabel>Murine Monoclonal Antibody 2B8</classLabel>
<deletedAxiom>&apos;Murine Monoclonal Antibody 2B8&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Murine Monoclonal Antibody 2B8&apos; SubClassOf &apos;Anti-CD20 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2524</classIRI>
<classLabel>Ocaratuzumab</classLabel>
<deletedAxiom>&apos;Ocaratuzumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Ocaratuzumab&apos; SubClassOf &apos;Anti-CD20 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162873</classIRI>
<classLabel>Autologous Active IL-7 Receptor Co-expressing GD2-specific CAR T-cells</classLabel>
<newAxiom>&apos;Autologous Active IL-7 Receptor Co-expressing GD2-specific CAR T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201491</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138911</classIRI>
<classLabel>EGFR NP_005219.2:p.P772_H773insNPH</classLabel>
<newAxiom>&apos;EGFR NP_005219.2:p.P772_H773insNPH&apos; SubClassOf &apos;Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant&apos; some &apos;EGFR Exon 20 Insertion Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138905</classIRI>
<classLabel>EGFR NP_005219.2:p.P772_V774insPHV</classLabel>
<newAxiom>&apos;EGFR NP_005219.2:p.P772_V774insPHV&apos; SubClassOf &apos;Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant&apos; some &apos;EGFR Exon 20 Insertion Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138902</classIRI>
<classLabel>EGFR NP_005219.2:p.D770_N771insGV</classLabel>
<newAxiom>&apos;EGFR NP_005219.2:p.D770_N771insGV&apos; SubClassOf &apos;Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant&apos; some &apos;EGFR Exon 20 Insertion Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138903</classIRI>
<classLabel>EGFR NP_005219.2:p.M766_A767insASV</classLabel>
<newAxiom>&apos;EGFR NP_005219.2:p.M766_A767insASV&apos; SubClassOf &apos;Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant&apos; some &apos;EGFR Exon 20 Insertion Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138904</classIRI>
<classLabel>EGFR NP_005219.2:p.P772_H773insNP</classLabel>
<newAxiom>&apos;EGFR NP_005219.2:p.P772_H773insNP&apos; SubClassOf &apos;Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant&apos; some &apos;EGFR Exon 20 Insertion Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C163976</classIRI>
<classLabel>Voxalatamab</classLabel>
<deletedAxiom>&apos;Voxalatamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Voxalatamab&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Voxalatamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
<newAxiom>&apos;Voxalatamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201543</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C163950</classIRI>
<classLabel>Anti-CCR4 Monoclonal Antibody</classLabel>
<deletedAxiom>&apos;Anti-CCR4 Monoclonal Antibody&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C163951</classIRI>
<classLabel>Anti-IL-6 Monoclonal Antibody</classLabel>
<deletedAxiom>&apos;Anti-IL-6 Monoclonal Antibody&apos; SubClassOf &apos;Targeted Therapy Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138995</classIRI>
<classLabel>Capmatinib Hydrochloride</classLabel>
<deletedAxiom>&apos;Capmatinib Hydrochloride&apos; SubClassOf &apos;Angiogenesis Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Capmatinib Hydrochloride&apos; SubClassOf &apos;c-Met Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124129</classIRI>
<classLabel>Type I Collagen</classLabel>
<deletedAxiom>&apos;Type I Collagen&apos; SubClassOf &apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Collagen&apos;</deletedAxiom>
<newAxiom>&apos;Type I Collagen&apos; SubClassOf &apos;Collagen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21177</classIRI>
<classLabel>MRE11/RAD50 Double-Strand Break Repair Complex</classLabel>
<newAxiom>&apos;MRE11/RAD50 Double-Strand Break Repair Complex&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Telomere Maintenance&apos;</newAxiom>
<newAxiom>&apos;MRE11/RAD50 Double-Strand Break Repair Complex&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Double Strand Break Repair&apos;</newAxiom>
<newAxiom>&apos;MRE11/RAD50 Double-Strand Break Repair Complex&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Meiotic Recombination&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21299</classIRI>
<classLabel>ATP-Binding Cassette Sub-Family B Member 6, Mitochondrial</classLabel>
<deletedAxiom>&apos;ATP-Binding Cassette Sub-Family B Member 6, Mitochondrial&apos; EquivalentTo &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Mitochondrion&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Hepatocellular Carcinoma&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Striated Muscle Tissue&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Heart&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Multidrug Resistance Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Drug Efflux&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transmembrane Transport&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ABCB6 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;ATP-Binding Cassette Sub-Family B Member 6, Mitochondrial&apos; EquivalentTo &apos;Translocase&apos; and &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Mitochondrion&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Hepatocellular Carcinoma&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Striated Muscle Tissue&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Heart&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Multidrug Resistance Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Drug Efflux&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transmembrane Transport&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ABCB6 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C94209</classIRI>
<classLabel>Allogeneic Natural Killer Cell Line MG4101</classLabel>
<deletedAxiom>&apos;Allogeneic Natural Killer Cell Line MG4101&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic Natural Killer Cell Line MG4101&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21209</classIRI>
<classLabel>DNA Repair Protein RAD51 Homolog 3</classLabel>
<deletedAxiom>&apos;DNA Repair Protein RAD51 Homolog 3&apos; EquivalentTo &apos;DNA Repair Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Homologous Recombination Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Myocardium&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Prostate Gland&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Testis&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Spleen&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;ATPase&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;DNA Binding Protein&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Hydrolase&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Fanconi Anemia Complementation Group Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Recombination Repair&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Meiotic Recombination&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RAD51C Gene&apos;)</deletedAxiom>
<newAxiom>&apos;DNA Repair Protein RAD51 Homolog 3&apos; EquivalentTo &apos;DNA Repair Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Homologous Recombination Pathway&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Myocardium&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Prostate Gland&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Testis&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Spleen&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201206) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;ATPase&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;DNA Binding Protein&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Hydrolase&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Fanconi Anemia Complementation Group Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Recombination Repair&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Meiotic Recombination&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RAD51C Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21264</classIRI>
<classLabel>ABCB6 Gene</classLabel>
<newAxiom>&apos;ABCB6 Gene&apos; SubClassOf &apos;Translocase Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177917</classIRI>
<classLabel>Allogeneic Anti-CD70-CAR T-cells ALLO-316</classLabel>
<newAxiom>&apos;Allogeneic Anti-CD70-CAR T-cells ALLO-316&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201176</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C163022</classIRI>
<classLabel>Epcoritamab</classLabel>
<deletedAxiom>&apos;Epcoritamab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Epcoritamab&apos; SubClassOf &apos;Anti-CD20 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Epcoritamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Epcoritamab&apos; SubClassOf &apos;Anti-CD20/Anti-CD3 Bispecific Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21567</classIRI>
<classLabel>DNA Repair Protein XRCC2</classLabel>
<deletedAxiom>&apos;DNA Repair Protein XRCC2&apos; EquivalentTo &apos;DNA Repair Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Homologous Recombination Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Hypersensitivity&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Fanconi Anemia Complementation Group Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Meiosis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Homologous Recombination&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Maintenance&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Recombination Repair&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;XRCC2 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;DNA Repair Protein XRCC2&apos; EquivalentTo &apos;DNA Repair Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Homologous Recombination Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Hypersensitivity&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201206) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Fanconi Anemia Complementation Group Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Meiosis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Homologous Recombination&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Maintenance&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Recombination Repair&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;XRCC2 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21578</classIRI>
<classLabel>TAP2 Gene</classLabel>
<newAxiom>&apos;TAP2 Gene&apos; SubClassOf &apos;Translocase Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21579</classIRI>
<classLabel>Antigen Peptide Transporter 2</classLabel>
<deletedAxiom>&apos;Antigen Peptide Transporter 2&apos; EquivalentTo &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Antigen Presentation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Antigen Processing and Presentation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Primary Immunodeficiency Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Phagocytosis Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Endoplasmic Reticulum&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Antigen Presenting Cell&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Antigen Processing&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immune Surveillance&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Peptide Transport&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TAP2 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Antigen Peptide Transporter 2&apos; EquivalentTo &apos;Translocase&apos; and &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Antigen Presentation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Antigen Processing and Presentation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Primary Immunodeficiency Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Phagocytosis Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Endoplasmic Reticulum&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Antigen Presenting Cell&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Antigen Processing&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immune Surveillance&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Peptide Transport&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TAP2 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21573</classIRI>
<classLabel>TAP1 Gene</classLabel>
<newAxiom>&apos;TAP1 Gene&apos; SubClassOf &apos;Translocase Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21574</classIRI>
<classLabel>Antigen Peptide Transporter 1</classLabel>
<deletedAxiom>&apos;Antigen Peptide Transporter 1&apos; EquivalentTo &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Antigen Presentation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Antigen Processing and Presentation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Primary Immunodeficiency Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Phagocytosis Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Endoplasmic Reticulum&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Endoplasmic Reticulum&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Colorectal Carcinoma&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Antigen Presenting Cell&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Antigen Processing&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immune Surveillance&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Peptide Transport&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TAP1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Antigen Peptide Transporter 1&apos; EquivalentTo &apos;Translocase&apos; and &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Antigen Presentation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Antigen Processing and Presentation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Primary Immunodeficiency Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Phagocytosis Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Endoplasmic Reticulum&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Endoplasmic Reticulum&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Colorectal Carcinoma&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Antigen Presenting Cell&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Antigen Processing&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immune Surveillance&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Peptide Transport&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TAP1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80060</classIRI>
<classLabel>Avutometinib</classLabel>
<newAxiom>&apos;Avutometinib&apos; SubClassOf &apos;Mitogen-Activated Protein Kinase Kinase Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177765</classIRI>
<classLabel>Anti-DLL3/CD3 Bispecific Antibody BI 764532</classLabel>
<deletedAxiom>&apos;Anti-DLL3/CD3 Bispecific Antibody BI 764532&apos; SubClassOf &apos;Bispecific Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-DLL3/CD3 Bispecific Antibody BI 764532&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-DLL3/CD3 Bispecific Antibody BI 764532&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177741</classIRI>
<classLabel>CD3-activating CD19 Bi-specific Antibody A-319</classLabel>
<deletedAxiom>&apos;CD3-activating CD19 Bi-specific Antibody A-319&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;CD3-activating CD19 Bi-specific Antibody A-319&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177482</classIRI>
<classLabel>ERBB2 NP_004439.2:p.L755X</classLabel>
<newAxiom>&apos;ERBB2 NP_004439.2:p.L755X&apos; SubClassOf &apos;Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant&apos; some &apos;ERBB2 Exon 19 Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104415</classIRI>
<classLabel>Gene-Modified HIV-Protected Hematopoietic Stem Cells</classLabel>
<deletedAxiom>&apos;Gene-Modified HIV-Protected Hematopoietic Stem Cells&apos; SubClassOf &apos;Genetically-engineered Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Gene-Modified HIV-Protected Hematopoietic Stem Cells&apos; SubClassOf &apos;Genetically Engineered Hematopoietic Stem Progenitor Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177260</classIRI>
<classLabel>EWSR1/SMAD3 Fusion Gene</classLabel>
<deletedAxiom>&apos;EWSR1/SMAD3 Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<newAxiom>&apos;EWSR1/SMAD3 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118845</classIRI>
<classLabel>Otopalatodigital Syndrome Type 1</classLabel>
<newAxiom>&apos;Otopalatodigital Syndrome Type 1&apos; SubClassOf &apos;X-Linked Inherited Disorder&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118949</classIRI>
<classLabel>Umbilical Cord Blood-derived Natural Killer Cells</classLabel>
<deletedAxiom>&apos;Umbilical Cord Blood-derived Natural Killer Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Umbilical Cord Blood-derived Natural Killer Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
<newAxiom>&apos;Umbilical Cord Blood-derived Natural Killer Cells&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104006</classIRI>
<classLabel>Anti-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocyte Cells</classLabel>
<newAxiom>&apos;Anti-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocyte Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118626</classIRI>
<classLabel>Anti-PSMA/CD3 Monoclonal Antibody MOR209/ES414</classLabel>
<deletedAxiom>&apos;Anti-PSMA/CD3 Monoclonal Antibody MOR209/ES414&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA/CD3 Monoclonal Antibody MOR209/ES414&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA/CD3 Monoclonal Antibody MOR209/ES414&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PSMA/CD3 Monoclonal Antibody MOR209/ES414&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201543</newAxiom>
<newAxiom>&apos;Anti-PSMA/CD3 Monoclonal Antibody MOR209/ES414&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177152</classIRI>
<classLabel>Umbilical Cord Blood-derived CD16-expressing Natural Killer Cells AB-101</classLabel>
<deletedAxiom>&apos;Umbilical Cord Blood-derived CD16-expressing Natural Killer Cells AB-101&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Umbilical Cord Blood-derived CD16-expressing Natural Killer Cells AB-101&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C89022</classIRI>
<classLabel>ABCA2 Gene</classLabel>
<newAxiom>&apos;ABCA2 Gene&apos; SubClassOf &apos;Translocase Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C89025</classIRI>
<classLabel>ATP-Binding Cassette Sub-Family A Member 2</classLabel>
<deletedAxiom>&apos;ATP-Binding Cassette Sub-Family A Member 2&apos; EquivalentTo &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Lysosome Assembly Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Lysosome&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Lipid Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cholesterol Homeostasis&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ABCA2 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;ATP-Binding Cassette Sub-Family A Member 2&apos; EquivalentTo &apos;Translocase&apos; and &apos;ABC Transporter&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Lysosome Assembly Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ABC Transporter Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Lysosome&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Lipid Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cholesterol Homeostasis&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ABCA2 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177111</classIRI>
<classLabel>Anti-MUC1/EGFR Bispecific Antibody Drug Conjugate M1231</classLabel>
<deletedAxiom>&apos;Anti-MUC1/EGFR Bispecific Antibody Drug Conjugate M1231&apos; SubClassOf &apos;EGFR-targeting Agent&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-MUC1/EGFR Bispecific Antibody Drug Conjugate M1231&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-MUC1/EGFR Bispecific Antibody Drug Conjugate M1231&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201551</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118780</classIRI>
<classLabel>Autosomal Dominant Torsion Dystonia 1</classLabel>
<newAxiom>&apos;Autosomal Dominant Torsion Dystonia 1&apos; SubClassOf &apos;Genetic Torsion Dystonia&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191228</classIRI>
<classLabel>Helper 1 T-Lymphocyte Subpopulation to Helper 1 T-Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;Helper 1 T-Lymphocyte Subpopulation to Helper 1 T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Helper 1 T-Lymphocyte Count&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C166258</classIRI>
<classLabel>Anti-CD3/Anti-GUCY2C Bispecific Antibody PF-07062119</classLabel>
<deletedAxiom>&apos;Anti-CD3/Anti-GUCY2C Bispecific Antibody PF-07062119&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD3/Anti-GUCY2C Bispecific Antibody PF-07062119&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5138</classIRI>
<classLabel>Breast Ductal Carcinoma In Situ, Cribriform Pattern</classLabel>
<deletedAxiom>&apos;Breast Ductal Carcinoma In Situ, Cribriform Pattern&apos; EquivalentTo &apos;Non-Invasive Cribriform Carcinoma&apos; and &apos;Breast Ductal Carcinoma In Situ&apos;</deletedAxiom>
<newAxiom>&apos;Breast Ductal Carcinoma In Situ, Cribriform Pattern&apos; EquivalentTo &apos;Non-Invasive Cribriform Carcinoma&apos; and &apos;Breast Ductal Carcinoma In Situ, Non-Comedo Type&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C146940</classIRI>
<classLabel>NY-ESO-1 TCR/sr39TK Lentiviral Vector-transduced Autologous PBSCs</classLabel>
<deletedAxiom>&apos;NY-ESO-1 TCR/sr39TK Lentiviral Vector-transduced Autologous PBSCs&apos; SubClassOf &apos;T-cell Receptor-engineered T-cells&apos;</deletedAxiom>
<newAxiom>&apos;NY-ESO-1 TCR/sr39TK Lentiviral Vector-transduced Autologous PBSCs&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201557</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107135</classIRI>
<classLabel>NDN wt Allele</classLabel>
<newAxiom>&apos;NDN wt Allele&apos; SubClassOf &apos;Gene_In_Chromosomal_Location&apos; some &apos;15q11.2&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107134</classIRI>
<classLabel>NDN Gene</classLabel>
<newAxiom>&apos;NDN Gene&apos; SubClassOf &apos;Transcription Factor Gene&apos;</newAxiom>
<newAxiom>&apos;NDN Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Transcriptional Repression&apos;</newAxiom>
<newAxiom>&apos;NDN Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Cell Growth Regulation&apos;</newAxiom>
<newAxiom>&apos;NDN Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Cell Cycle Regulation Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107136</classIRI>
<classLabel>Necdin</classLabel>
<deletedAxiom>&apos;Necdin&apos; SubClassOf &apos;Cell Cycle Protein&apos;</deletedAxiom>
<deletedAxiom>&apos;Necdin&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;NDN Gene&apos;</deletedAxiom>
<newAxiom>&apos;Necdin&apos; EquivalentTo &apos;Transcription Factor&apos; and &apos;Cell Cycle Protein&apos; and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Transcription Repressor/Corepressor&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Repression&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Growth Regulation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Cycle Regulation Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;NDN Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107160</classIRI>
<classLabel>Oncolytic Adenovirus ICOVIR5-infected Autologous Mesenchymal Stem Cells</classLabel>
<newAxiom>&apos;Oncolytic Adenovirus ICOVIR5-infected Autologous Mesenchymal Stem Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201556</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107190</classIRI>
<classLabel>CD33CAR-CD3zeta-4-1BB-expressing Autologous T-Lymphocytes</classLabel>
<newAxiom>&apos;CD33CAR-CD3zeta-4-1BB-expressing Autologous T-Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201495</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C146820</classIRI>
<classLabel>Tidutamab</classLabel>
<deletedAxiom>&apos;Tidutamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Tidutamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C146824</classIRI>
<classLabel>Etevritamab</classLabel>
<deletedAxiom>&apos;Etevritamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Etevritamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C146806</classIRI>
<classLabel>Allogeneic CD123-specific Universal CAR123-expressing T-lymphocytes</classLabel>
<newAxiom>&apos;Allogeneic CD123-specific Universal CAR123-expressing T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201493</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5630</classIRI>
<classLabel>Aleukemic Monocytic Leukemia Cutis</classLabel>
<deletedAxiom>&apos;Aleukemic Monocytic Leukemia Cutis&apos; EquivalentTo &apos;Acute Monocytic Leukemia&apos; and &apos;Aleukemic Leukemia Cutis&apos;</deletedAxiom>
<newAxiom>&apos;Aleukemic Monocytic Leukemia Cutis&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201127 and &apos;Acute Monocytic Leukemia&apos; and &apos;Aleukemic Leukemia Cutis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171840</classIRI>
<classLabel>Talquetamab</classLabel>
<deletedAxiom>&apos;Talquetamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Talquetamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171450</classIRI>
<classLabel>Perenostobart</classLabel>
<deletedAxiom>&apos;Perenostobart&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Perenostobart&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201164</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C146667</classIRI>
<classLabel>Anti-c-Met Antibody-drug Conjugate HTI-1066</classLabel>
<deletedAxiom>&apos;Anti-c-Met Antibody-drug Conjugate HTI-1066&apos; SubClassOf &apos;c-Met-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-c-Met Antibody-drug Conjugate HTI-1066&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201552</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132017</classIRI>
<classLabel>Enapotamab Vedotin</classLabel>
<deletedAxiom>&apos;Enapotamab Vedotin&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Enapotamab Vedotin&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171577</classIRI>
<classLabel>Ifinatamab Deruxtecan</classLabel>
<deletedAxiom>&apos;Ifinatamab Deruxtecan&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Ifinatamab Deruxtecan&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201516</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185981</classIRI>
<classLabel>Alpha-Beta Cytotoxic T-Lymphocyte Subpopulation Count</classLabel>
<newAxiom>&apos;Alpha-Beta Cytotoxic T-Lymphocyte Subpopulation Count&apos; SubClassOf &apos;Cytotoxic T-Lymphocyte Subpopulation Count&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171318</classIRI>
<classLabel>Autologous Anti-B7-H3/CD19 CAR T-cells SCRI-CARB7H3(s)x19</classLabel>
<newAxiom>&apos;Autologous Anti-B7-H3/CD19 CAR T-cells SCRI-CARB7H3(s)x19&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201492</newAxiom>
<newAxiom>&apos;Autologous Anti-B7-H3/CD19 CAR T-cells SCRI-CARB7H3(s)x19&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75741</classIRI>
<classLabel>Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 2</classLabel>
<deletedAxiom>&apos;Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 2&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;</deletedAxiom>
<deletedAxiom>&apos;Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 2&apos; SubClassOf &apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;</deletedAxiom>
<deletedAxiom>&apos;Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 2&apos; SubClassOf &apos;Regulatory Protein&apos;</deletedAxiom>
<deletedAxiom>&apos;Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 2&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;NIPA2 Gene&apos;</deletedAxiom>
<newAxiom>&apos;Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 2&apos; EquivalentTo &apos;Transport Protein&apos; and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Early Endosome&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Endosome&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Solute Carrier Family&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transmembrane Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;NIPA2 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75740</classIRI>
<classLabel>Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 1</classLabel>
<deletedAxiom>&apos;Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 1&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Neural Development&apos;</deletedAxiom>
<deletedAxiom>&apos;Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 1&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;</deletedAxiom>
<deletedAxiom>&apos;Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 1&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;NIPA1 Gene&apos;</deletedAxiom>
<deletedAxiom>&apos;Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 1&apos; SubClassOf &apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;</deletedAxiom>
<deletedAxiom>&apos;Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 1&apos; SubClassOf &apos;Regulatory Protein&apos;</deletedAxiom>
<newAxiom>&apos;Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 1&apos; EquivalentTo &apos;Transport Protein&apos; and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Early Endosome&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Endosome&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Solute Carrier Family&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Neural Development&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transmembrane Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;NIPA1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75738</classIRI>
<classLabel>NIPA2 Gene</classLabel>
<deletedAxiom>&apos;NIPA2 Gene&apos; SubClassOf &apos;Regulatory Gene&apos;</deletedAxiom>
<newAxiom>&apos;NIPA2 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Ion Transport Process&apos;</newAxiom>
<newAxiom>&apos;NIPA2 Gene&apos; SubClassOf &apos;Transport Protein Gene&apos;</newAxiom>
<newAxiom>&apos;NIPA2 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Transmembrane Transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75736</classIRI>
<classLabel>NIPA1 Gene</classLabel>
<deletedAxiom>&apos;NIPA1 Gene&apos; SubClassOf &apos;Regulatory Gene&apos;</deletedAxiom>
<newAxiom>&apos;NIPA1 Gene&apos; SubClassOf &apos;Transport Protein Gene&apos;</newAxiom>
<newAxiom>&apos;NIPA1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Ion Transport Process&apos;</newAxiom>
<newAxiom>&apos;NIPA1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Transmembrane Transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185602</classIRI>
<classLabel>Anti-CD3/Anti-Claudin18.2 Bispecific Antibody IBI389</classLabel>
<deletedAxiom>&apos;Anti-CD3/Anti-Claudin18.2 Bispecific Antibody IBI389&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD3/Anti-Claudin18.2 Bispecific Antibody IBI389&apos; SubClassOf &apos;Bispecific Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD3/Anti-Claudin18.2 Bispecific Antibody IBI389&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185607</classIRI>
<classLabel>Anti-Claudin18.2 CAR T Cells IBI345</classLabel>
<deletedAxiom>&apos;Anti-Claudin18.2 CAR T Cells IBI345&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-Claudin18.2 CAR T Cells IBI345&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Anti-Claudin18.2 CAR T Cells IBI345&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201172</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171093</classIRI>
<classLabel>Autologous Bispecific CD19/CD22-targeted CAR-T Cells GC022</classLabel>
<newAxiom>&apos;Autologous Bispecific CD19/CD22-targeted CAR-T Cells GC022&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201173</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171046</classIRI>
<classLabel>KIR3DL2 wt Allele</classLabel>
<deletedAxiom>&apos;KIR3DL2 wt Allele&apos; SubClassOf &apos;Gene_In_Chromosomal_Location&apos; some &apos;19q13.4&apos;</deletedAxiom>
<newAxiom>&apos;KIR3DL2 wt Allele&apos; SubClassOf &apos;Gene_In_Chromosomal_Location&apos; some &apos;19q13.42&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185677</classIRI>
<classLabel>Anti-FLT3/CD3 Bispecific Antibody CLN-049</classLabel>
<deletedAxiom>&apos;Anti-FLT3/CD3 Bispecific Antibody CLN-049&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-FLT3/CD3 Bispecific Antibody CLN-049&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-FLT3/CD3 Bispecific Antibody CLN-049&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185664</classIRI>
<classLabel>Anti-PSMA/CD3 Bispecific Antibody REGN4336</classLabel>
<deletedAxiom>&apos;Anti-PSMA/CD3 Bispecific Antibody REGN4336&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA/CD3 Bispecific Antibody REGN4336&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA/CD3 Bispecific Antibody REGN4336&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PSMA/CD3 Bispecific Antibody REGN4336&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
<newAxiom>&apos;Anti-PSMA/CD3 Bispecific Antibody REGN4336&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201543</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171167</classIRI>
<classLabel>Autologous Anti-CD123 CAR-T Cells</classLabel>
<newAxiom>&apos;Autologous Anti-CD123 CAR-T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201493</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185445</classIRI>
<classLabel>Autologous CD34+-enriched HSPCs Transduced with LV Vector Carrying TCIRG1 Gene RP-L401</classLabel>
<deletedAxiom>&apos;Autologous CD34+-enriched HSPCs Transduced with LV Vector Carrying TCIRG1 Gene RP-L401&apos; SubClassOf &apos;Gene Therapy Agent&apos;</deletedAxiom>
<deletedAxiom>&apos;Autologous CD34+-enriched HSPCs Transduced with LV Vector Carrying TCIRG1 Gene RP-L401&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Autologous CD34+-enriched HSPCs Transduced with LV Vector Carrying TCIRG1 Gene RP-L401&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185418</classIRI>
<classLabel>Anti-CCR8 Monoclonal Antibody S-531011</classLabel>
<newAxiom>&apos;Anti-CCR8 Monoclonal Antibody S-531011&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61503</classIRI>
<classLabel>Farletuzumab</classLabel>
<newAxiom>&apos;Farletuzumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61502</classIRI>
<classLabel>Mapatumumab</classLabel>
<newAxiom>&apos;Mapatumumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185598</classIRI>
<classLabel>Autologous Anti-mesothelin CAR-IL-7-CCL19-expressing T-lymphocytes TAK-103</classLabel>
<newAxiom>&apos;Autologous Anti-mesothelin CAR-IL-7-CCL19-expressing T-lymphocytes TAK-103&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201275</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185590</classIRI>
<classLabel>Autologous Anti-EGFR/Anti-IL13Ralpha2 CAR T-cells</classLabel>
<newAxiom>&apos;Autologous Anti-EGFR/Anti-IL13Ralpha2 CAR T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201175</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172063</classIRI>
<classLabel>Autologous Anti-CD20 CAR Transduced CD4/CD8 Enriched T-cells MB-CART20.1</classLabel>
<newAxiom>&apos;Autologous Anti-CD20 CAR Transduced CD4/CD8 Enriched T-cells MB-CART20.1&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186615</classIRI>
<classLabel>FET/CREB Family Fusion Gene</classLabel>
<deletedAxiom>&apos;FET/CREB Family Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<deletedAxiom>&apos;FET/CREB Family Fusion Gene&apos; SubClassOf &apos;Gene_Has_Abnormality&apos; some &apos;FET Family Gene Translocation&apos;</deletedAxiom>
<newAxiom>&apos;FET/CREB Family Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C147028</classIRI>
<classLabel>Pavurutamab</classLabel>
<deletedAxiom>&apos;Pavurutamab&apos; SubClassOf &apos;Anti-BCMA Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Pavurutamab&apos; SubClassOf &apos;Anti-BCMA/CD3 Bispecific Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172057</classIRI>
<classLabel>Autologous Anti-CD19/CD20 Bispecific Nanobody-based CAR-T cells</classLabel>
<newAxiom>&apos;Autologous Anti-CD19/CD20 Bispecific Nanobody-based CAR-T cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186671</classIRI>
<classLabel>Adenosine Receptor A2A/A2B Antagonist M1069</classLabel>
<deletedAxiom>&apos;Adenosine Receptor A2A/A2B Antagonist M1069&apos; SubClassOf &apos;Immunostimulant&apos;</deletedAxiom>
<newAxiom>&apos;Adenosine Receptor A2A/A2B Antagonist M1069&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201170</newAxiom>
<newAxiom>&apos;Adenosine Receptor A2A/A2B Antagonist M1069&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201171</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186670</classIRI>
<classLabel>Anti-EGFR/anti-HER3 Antibody-drug Conjugate BL-B01D1</classLabel>
<newAxiom>&apos;Anti-EGFR/anti-HER3 Antibody-drug Conjugate BL-B01D1&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201551</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186677</classIRI>
<classLabel>FET/ETS Family Fusion Gene</classLabel>
<deletedAxiom>&apos;FET/ETS Family Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<deletedAxiom>&apos;FET/ETS Family Fusion Gene&apos; SubClassOf &apos;Gene_Has_Abnormality&apos; some &apos;FET Family Gene Translocation&apos;</deletedAxiom>
<newAxiom>&apos;FET/ETS Family Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186666</classIRI>
<classLabel>Autologous Anti-CD7 CAR T Cells PA3-17</classLabel>
<newAxiom>&apos;Autologous Anti-CD7 CAR T Cells PA3-17&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201177</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186665</classIRI>
<classLabel>Anti-5T4 CAR-NK Cells</classLabel>
<deletedAxiom>&apos;Anti-5T4 CAR-NK Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Anti-5T4 CAR-NK Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
<newAxiom>&apos;Anti-5T4 CAR-NK Cells&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186668</classIRI>
<classLabel>Anti-B7-H3 CAR T Cells TAA06</classLabel>
<deletedAxiom>&apos;Anti-B7-H3 CAR T Cells TAA06&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-B7-H3 CAR T Cells TAA06&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anti-B7-H3 CAR T Cells TAA06&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201492</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186655</classIRI>
<classLabel>Allogeneic CD16-expressing Natural Killer Cells CYNK-101</classLabel>
<deletedAxiom>&apos;Allogeneic CD16-expressing Natural Killer Cells CYNK-101&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic CD16-expressing Natural Killer Cells CYNK-101&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186374</classIRI>
<classLabel>Anti-CCR8 Monoclonal Antibody LM-108</classLabel>
<newAxiom>&apos;Anti-CCR8 Monoclonal Antibody LM-108&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186377</classIRI>
<classLabel>Anti-EGFRvIII/CD3 Bispecific Antibody RO7428731</classLabel>
<deletedAxiom>&apos;Anti-EGFRvIII/CD3 Bispecific Antibody RO7428731&apos; SubClassOf &apos;Bispecific Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-EGFRvIII/CD3 Bispecific Antibody RO7428731&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-EGFRvIII/CD3 Bispecific Antibody RO7428731&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186366</classIRI>
<classLabel>Anti-CD20/anti-CD3 Bispecific Antibody CM355</classLabel>
<deletedAxiom>&apos;Anti-CD20/anti-CD3 Bispecific Antibody CM355&apos; SubClassOf &apos;CD20-targeting Agent&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD20/anti-CD3 Bispecific Antibody CM355&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD20/anti-CD3 Bispecific Antibody CM355&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD20/anti-CD3 Bispecific Antibody CM355&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD20/anti-CD3 Bispecific Antibody CM355&apos; SubClassOf &apos;Anti-CD20/Anti-CD3 Bispecific Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C152916</classIRI>
<classLabel>Vorsetuzumab</classLabel>
<deletedAxiom>&apos;Vorsetuzumab&apos; SubClassOf &apos;CD70-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Vorsetuzumab&apos; SubClassOf &apos;Anti-CD70 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95206</classIRI>
<classLabel>Depatuxizumab</classLabel>
<deletedAxiom>&apos;Depatuxizumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Depatuxizumab&apos; SubClassOf &apos;Anti-EGFR Monoclonal Antibody&apos;</newAxiom>
<newAxiom>&apos;Depatuxizumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113439</classIRI>
<classLabel>Anti-PSMA Monoclonal Antibody MDX1201-A488</classLabel>
<deletedAxiom>&apos;Anti-PSMA Monoclonal Antibody MDX1201-A488&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA Monoclonal Antibody MDX1201-A488&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA Monoclonal Antibody MDX1201-A488&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PSMA Monoclonal Antibody MDX1201-A488&apos; SubClassOf &apos;Imaging Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186430</classIRI>
<classLabel>iPSC-derived Anti-BCMA CAR/CD16/IL-15RF-expressing CD38-eliminated NK Cells FT576</classLabel>
<deletedAxiom>&apos;iPSC-derived Anti-BCMA CAR/CD16/IL-15RF-expressing CD38-eliminated NK Cells FT576&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;iPSC-derived Anti-BCMA CAR/CD16/IL-15RF-expressing CD38-eliminated NK Cells FT576&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113292</classIRI>
<classLabel>Exosome Complex Component RRP46</classLabel>
<deletedAxiom>&apos;Exosome Complex Component RRP46&apos; EquivalentTo &apos;Regulatory Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;RNA Degradation Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Exosome&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cytosol&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;PH Domain&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;RNA Processing&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;EXOSC5 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Exosome Complex Component RRP46&apos; EquivalentTo &apos;RNA Binding Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;RNA Degradation Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Exosome&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cytosol&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;RNA Processing&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;EXOSC5 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113290</classIRI>
<classLabel>EXOSC5 Gene</classLabel>
<deletedAxiom>&apos;EXOSC5 Gene&apos; SubClassOf &apos;Regulatory Gene&apos;</deletedAxiom>
<newAxiom>&apos;EXOSC5 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;RNA Binding&apos;</newAxiom>
<newAxiom>&apos;EXOSC5 Gene&apos; SubClassOf &apos;Ligand Binding Protein Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C152526</classIRI>
<classLabel>Technetium Tc-99M Fanolesomab</classLabel>
<deletedAxiom>&apos;Technetium Tc-99M Fanolesomab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95755</classIRI>
<classLabel>Ulocuplumab</classLabel>
<newAxiom>&apos;Ulocuplumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95728</classIRI>
<classLabel>Anti-CEA BiTE Monoclonal Antibody AMG211</classLabel>
<deletedAxiom>&apos;Anti-CEA BiTE Monoclonal Antibody AMG211&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CEA BiTE Monoclonal Antibody AMG211&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95798</classIRI>
<classLabel>Vedolizumab</classLabel>
<newAxiom>&apos;Vedolizumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95797</classIRI>
<classLabel>Teprotumumab</classLabel>
<deletedAxiom>&apos;Teprotumumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Teprotumumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Teprotumumab&apos; SubClassOf &apos;Anti-IGF1R Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95787</classIRI>
<classLabel>Itolizumab</classLabel>
<deletedAxiom>&apos;Itolizumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Itolizumab&apos; SubClassOf &apos;Anti-CD6 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95789</classIRI>
<classLabel>Naptumomab Estafenatox</classLabel>
<deletedAxiom>&apos;Naptumomab Estafenatox&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Naptumomab Estafenatox&apos; SubClassOf &apos;Immunoconjugate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95785</classIRI>
<classLabel>Foralumab</classLabel>
<deletedAxiom>&apos;Foralumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Foralumab&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186000</classIRI>
<classLabel>Alpha-Beta Helper T-Lymphocyte Subpopulation Count</classLabel>
<newAxiom>&apos;Alpha-Beta Helper T-Lymphocyte Subpopulation Count&apos; SubClassOf &apos;Alpha-Beta Helper T-Lymphocyte Count&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95782</classIRI>
<classLabel>Cantuzumab Mertansine</classLabel>
<deletedAxiom>&apos;Cantuzumab Mertansine&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Cantuzumab Mertansine&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95760</classIRI>
<classLabel>Anti-CD3/Anti-CD20 Trifunctional Bispecific Monoclonal Antibody FBTA05</classLabel>
<deletedAxiom>&apos;Anti-CD3/Anti-CD20 Trifunctional Bispecific Monoclonal Antibody FBTA05&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD3/Anti-CD20 Trifunctional Bispecific Monoclonal Antibody FBTA05&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD3/Anti-CD20 Trifunctional Bispecific Monoclonal Antibody FBTA05&apos; SubClassOf &apos;Anti-CD20/Anti-CD3 Bispecific Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95710</classIRI>
<classLabel>Labetuzumab Govitecan</classLabel>
<deletedAxiom>&apos;Labetuzumab Govitecan&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Labetuzumab Govitecan&apos; SubClassOf &apos;CEA-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Labetuzumab Govitecan&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201549</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95712</classIRI>
<classLabel>Nesvacumab</classLabel>
<newAxiom>&apos;Nesvacumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95719</classIRI>
<classLabel>Tarextumab</classLabel>
<newAxiom>&apos;Tarextumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95707</classIRI>
<classLabel>Anti-PSMA Monoclonal Antibody-MMAE Conjugate</classLabel>
<deletedAxiom>&apos;Anti-PSMA Monoclonal Antibody-MMAE Conjugate&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA Monoclonal Antibody-MMAE Conjugate&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PSMA Monoclonal Antibody-MMAE Conjugate&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201544</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C152371</classIRI>
<classLabel>Sirukumab</classLabel>
<deletedAxiom>&apos;Sirukumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Sirukumab&apos; SubClassOf &apos;Anti-IL-6 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C152315</classIRI>
<classLabel>Secukinumab</classLabel>
<deletedAxiom>&apos;Secukinumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Secukinumab&apos; SubClassOf &apos;Anti-IL17A Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191762</classIRI>
<classLabel>Autologous Tumor Infiltrating Lymphocytes TBio-4101</classLabel>
<deletedAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes TBio-4101&apos; SubClassOf &apos;Therapeutic Tumor Infiltrating Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes TBio-4101&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
<newAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes TBio-4101&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191739</classIRI>
<classLabel>Anti-CD33 CAR T-cells</classLabel>
<deletedAxiom>&apos;Anti-CD33 CAR T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD33 CAR T-cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD33 CAR T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201495</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191715</classIRI>
<classLabel>Anti-HER2 GSPT1 Degrader ORM-5029</classLabel>
<deletedAxiom>&apos;Anti-HER2 GSPT1 Degrader ORM-5029&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-HER2 GSPT1 Degrader ORM-5029&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-HER2 GSPT1 Degrader ORM-5029&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191777</classIRI>
<classLabel>Anti-TNFR2 Monoclonal Antibody SIM1811-03</classLabel>
<deletedAxiom>&apos;Anti-TNFR2 Monoclonal Antibody SIM1811-03&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-TNFR2 Monoclonal Antibody SIM1811-03&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201522</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127120</classIRI>
<classLabel>Vibecotamab</classLabel>
<deletedAxiom>&apos;Vibecotamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Vibecotamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
<newAxiom>&apos;Vibecotamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201511</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C166700</classIRI>
<classLabel>Ozanimod Hydrochloride</classLabel>
<deletedAxiom>&apos;Ozanimod Hydrochloride&apos; SubClassOf &apos;Immunotherapeutic Agent&apos;</deletedAxiom>
<newAxiom>&apos;Ozanimod Hydrochloride&apos; SubClassOf &apos;Immunosuppressant&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C166699</classIRI>
<classLabel>Imciromab Pentetate</classLabel>
<deletedAxiom>&apos;Imciromab Pentetate&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Imciromab Pentetate&apos; SubClassOf &apos;Immunoconjugate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127001</classIRI>
<classLabel>Gap Junction Beta-2 Protein</classLabel>
<deletedAxiom>&apos;Gap Junction Beta-2 Protein&apos; EquivalentTo &apos;Transport Protein&apos; and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Gap Junction&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Hearing&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Restricted Diffusion&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;GJB2 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Gap Junction Beta-2 Protein&apos; EquivalentTo &apos;Transport Protein&apos; and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Gap Junction&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intercellular Communication Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Hearing&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transmembrane Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intercellular Transport Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Restricted Diffusion&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;GJB2 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17394</classIRI>
<classLabel>Retinoblastoma-Associated Protein</classLabel>
<deletedAxiom>&apos;Retinoblastoma-Associated Protein&apos; EquivalentTo &apos;Cell Cycle Protein&apos; and &apos;Transcription Regulatory Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cell Cycle Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Ribosomal Biogenesis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;BTG Cell Cycle Regulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cyclin Regulation of Cell Cycle Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Fas Signaling Pathway BioCarta&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cyclin E Degradation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;G1/S Checkpoint Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Human Cytomegalovirus Infection Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;HIV-I Nef in Apoptosis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;p27 Regulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;p53 Signaling Pathway BioCarta&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cell Cycle Progression Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;PPAR-alpha Gene Regulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;G1 to S Transition Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;RB Checkpoint Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;E2F1 Degradation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Telomere Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Terc Regulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Interferon Signaling Modulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;TNFR1 Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Non-Small Cell Lung Cancer Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Pancreatic Cancer Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Bladder Cancer Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Chronic Myeloid Leukemia Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Melanoma Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Glioblastoma Multiforme Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Small Cell Lung Cancer Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Prostate Cancer Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ATF-2 Transcription Factor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Ceramide Signaling Pathway PID&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;p53 Effector Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;E2F Transcription Factor Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;FOXM1 Transcription Factor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Regulation of Retinoblastoma Protein Pathway&apos;) and (&apos;Gene_Product_Is_Biomarker_Type&apos; some &apos;Tumor Marker&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Phosphoprotein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Is_Biomarker_Of&apos; some &apos;Retinoblastoma&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Transcription Repressor/Corepressor&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Repression&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Cycle Regulation Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Proliferation Regulatory Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Tumor Suppression&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RB1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Retinoblastoma-Associated Protein&apos; EquivalentTo &apos;Transcription Factor&apos; and &apos;Cell Cycle Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cell Cycle Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Ribosomal Biogenesis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;BTG Cell Cycle Regulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cyclin Regulation of Cell Cycle Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Fas Signaling Pathway BioCarta&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cyclin E Degradation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;G1/S Checkpoint Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Human Cytomegalovirus Infection Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;HIV-I Nef in Apoptosis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;p27 Regulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;p53 Signaling Pathway BioCarta&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cell Cycle Progression Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;PPAR-alpha Gene Regulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;G1 to S Transition Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;RB Checkpoint Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;E2F1 Degradation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Telomere Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Terc Regulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Interferon Signaling Modulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;TNFR1 Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Non-Small Cell Lung Cancer Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Pancreatic Cancer Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Bladder Cancer Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Chronic Myeloid Leukemia Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Melanoma Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Glioblastoma Multiforme Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Small Cell Lung Cancer Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Prostate Cancer Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;ATF-2 Transcription Factor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Ceramide Signaling Pathway PID&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;p53 Effector Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;E2F Transcription Factor Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;FOXM1 Transcription Factor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Regulation of Retinoblastoma Protein Pathway&apos;) and (&apos;Gene_Product_Is_Biomarker_Type&apos; some &apos;Tumor Marker&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Phosphoprotein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Is_Biomarker_Of&apos; some &apos;Retinoblastoma&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Transcription Repressor/Corepressor&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Repression&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Cycle Regulation Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Proliferation Regulatory Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Tumor Suppression&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RB1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191263</classIRI>
<classLabel>Naive Helper T-Lymphocyte Subpopulation to Naive Helper T-Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;Naive Helper T-Lymphocyte Subpopulation to Naive Helper T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<deletedAxiom>&apos;Naive Helper T-Lymphocyte Subpopulation to Naive Helper T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Helper T-Lymphocytes Count&apos;</deletedAxiom>
<newAxiom>&apos;Naive Helper T-Lymphocyte Subpopulation to Naive Helper T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Naive Helper T-Lymphocyte Subpopulation to Helper T-Lymphocyte Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191254</classIRI>
<classLabel>Central Memory Helper T-Lymphocyte to Helper T-Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;Central Memory Helper T-Lymphocyte to Helper T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<deletedAxiom>&apos;Central Memory Helper T-Lymphocyte to Helper T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Helper T-Lymphocytes Count&apos;</deletedAxiom>
<newAxiom>&apos;Central Memory Helper T-Lymphocyte to Helper T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Helper T-Lymphocytes to Total T-Lymphocytes Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191252</classIRI>
<classLabel>Cytotoxic T-Lymphocyte Subpopulation to T-Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;Cytotoxic T-Lymphocyte Subpopulation to T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<deletedAxiom>&apos;Cytotoxic T-Lymphocyte Subpopulation to T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;T-Lymphocyte Count&apos;</deletedAxiom>
<newAxiom>&apos;Cytotoxic T-Lymphocyte Subpopulation to T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;T-Lymphocytes Subpopulation to Total T-Lymphocytes Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C106429</classIRI>
<classLabel>PBTL CD19CAR-28/CD137/zeta</classLabel>
<deletedAxiom>&apos;PBTL CD19CAR-28/CD137/zeta&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<deletedAxiom>&apos;PBTL CD19CAR-28/CD137/zeta&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4188</classIRI>
<classLabel>Comedocarcinoma</classLabel>
<deletedAxiom>&apos;Comedocarcinoma&apos; EquivalentTo &apos;Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Comedo Necrosis&apos;)</deletedAxiom>
<newAxiom>&apos;Comedocarcinoma&apos; EquivalentTo &apos;Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Comedo Necrosis&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179567</classIRI>
<classLabel>Autologous Anti-B7-H3 CAR T Cells</classLabel>
<newAxiom>&apos;Autologous Anti-B7-H3 CAR T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201492</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179557</classIRI>
<classLabel>CD8 Enriched Young Autologous Tumor-infiltrating Lymphocytes</classLabel>
<deletedAxiom>&apos;CD8 Enriched Young Autologous Tumor-infiltrating Lymphocytes&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;CD8 Enriched Young Autologous Tumor-infiltrating Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170913</classIRI>
<classLabel>Autologous Anti-CD147 CAR T-cells</classLabel>
<deletedAxiom>&apos;Autologous Anti-CD147 CAR T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Autologous Anti-CD147 CAR T-cells&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Anti-CD147 CAR T-cells&apos; SubClassOf &apos;Autologous CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170903</classIRI>
<classLabel>Anti-CD19 iCAR NK Cells</classLabel>
<deletedAxiom>&apos;Anti-CD19 iCAR NK Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD19 iCAR NK Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179288</classIRI>
<classLabel>Anti-c-Met/MMAE ADC RC108</classLabel>
<deletedAxiom>&apos;Anti-c-Met/MMAE ADC RC108&apos; SubClassOf &apos;c-Met-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-c-Met/MMAE ADC RC108&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201552</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179281</classIRI>
<classLabel>CD19-targeted CAR T2 Cells</classLabel>
<deletedAxiom>&apos;CD19-targeted CAR T2 Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179284</classIRI>
<classLabel>CXCR4-modified Anti-BCMA CAR T Cells</classLabel>
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<changedClass>
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<classLabel>Autologous Anti-CD30 CAR T Cells HSP-CAR30</classLabel>
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<changedClass>
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<classLabel>Anti-GD2/PSMA/CD276 4SCAR-expressing T-cells</classLabel>
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<deletedAxiom>&apos;Anti-GD2/PSMA/CD276 4SCAR-expressing T-cells&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-GD2/PSMA/CD276 4SCAR-expressing T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Anti-GD2/PSMA/CD276 4SCAR-expressing T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201491</newAxiom>
<newAxiom>&apos;Anti-GD2/PSMA/CD276 4SCAR-expressing T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201492</newAxiom>
<newAxiom>&apos;Anti-GD2/PSMA/CD276 4SCAR-expressing T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201178</newAxiom>
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<classLabel>iC9-GD2-CD28-OX40-expressing T Lymphocytes</classLabel>
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<deletedAxiom>&apos;iC9-GD2-CD28-OX40-expressing T Lymphocytes&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;iC9-GD2-CD28-OX40-expressing T Lymphocytes&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;iC9-GD2-CD28-OX40-expressing T Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201491</newAxiom>
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<classLabel>Tenvumestrocel</classLabel>
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<newAxiom>&apos;Tenvumestrocel&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</newAxiom>
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<classLabel>Gresonitamab</classLabel>
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<newAxiom>&apos;Gresonitamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
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<classLabel>Azamidugene Autotemcel</classLabel>
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<classLabel>Donor-derived Haploidentical IL-21-Expanded Natural Killer Cells</classLabel>
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<newAxiom>&apos;Donor-derived Haploidentical IL-21-Expanded Natural Killer Cells&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</newAxiom>
<newAxiom>&apos;Donor-derived Haploidentical IL-21-Expanded Natural Killer Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
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<changedClass>
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<classLabel>Tasadenoturev-infected Allogeneic Bone Marrow-derived Mesenchymal Stem Cells</classLabel>
<newAxiom>&apos;Tasadenoturev-infected Allogeneic Bone Marrow-derived Mesenchymal Stem Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201556</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Dacetuzumab</classLabel>
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<newAxiom>&apos;Dacetuzumab&apos; SubClassOf &apos;Anti-CD40 Monoclonal Antibody&apos;</newAxiom>
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<changedClass>
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<classLabel>Momelotinib Dihydrochloride</classLabel>
<newAxiom>&apos;Momelotinib Dihydrochloride&apos; SubClassOf &apos;ALK Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Autologous iC9-GD2-CAR-expressing VZV-specific T Lymphocytes</classLabel>
<newAxiom>&apos;Autologous iC9-GD2-CAR-expressing VZV-specific T Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201491</newAxiom>
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<newAxiom>&apos;TGFbDNRII-transduced Autologous Tumor Infiltrating Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
<newAxiom>&apos;TGFbDNRII-transduced Autologous Tumor Infiltrating Lymphocytes&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
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<classLabel>Solid Pseudopapillary Neoplasm of the Pancreas</classLabel>
<deletedAxiom>&apos;Solid Pseudopapillary Neoplasm of the Pancreas&apos; EquivalentTo &apos;Malignant Exocrine Pancreas Neoplasm&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;CTNNB1 Gene Mutation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Hemorrhagic Change&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lobulated Growth Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Pseudopapillary Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Low Grade Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Low Grade&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tumor Vascular Invasion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Encapsulated Mass&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cystic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Perineural Invasion&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CTNNB1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Solid Pseudopapillary Neoplasm of the Pancreas&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201136 and &apos;Malignant Exocrine Pancreas Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Hemorrhagic Change&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tumor Vascular Invasion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Encapsulated Mass&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Perineural Invasion&apos;)</newAxiom>
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<classLabel>Dimerizing Agent Regulated Immunoreceptor Complex-expressing CD33-specific Autologous CAR T Cells SC-DARIC33</classLabel>
<deletedAxiom>&apos;Dimerizing Agent Regulated Immunoreceptor Complex-expressing CD33-specific Autologous CAR T Cells SC-DARIC33&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<deletedAxiom>&apos;Dimerizing Agent Regulated Immunoreceptor Complex-expressing CD33-specific Autologous CAR T Cells SC-DARIC33&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Dimerizing Agent Regulated Immunoreceptor Complex-expressing CD33-specific Autologous CAR T Cells SC-DARIC33&apos; SubClassOf &apos;Autologous CAR-T Cells&apos;</newAxiom>
<newAxiom>&apos;Dimerizing Agent Regulated Immunoreceptor Complex-expressing CD33-specific Autologous CAR T Cells SC-DARIC33&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201495</newAxiom>
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<classLabel>Alpha/beta T-cell/CD19+ B-cell-depleted Unrelated or Partially Matched Donor-derived Allogeneic Peripheral Blood Stem Cells</classLabel>
<deletedAxiom>&apos;Alpha/beta T-cell/CD19+ B-cell-depleted Unrelated or Partially Matched Donor-derived Allogeneic Peripheral Blood Stem Cells&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Alpha/beta T-cell/CD19+ B-cell-depleted Unrelated or Partially Matched Donor-derived Allogeneic Peripheral Blood Stem Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201557</newAxiom>
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<classLabel>Nivobotulinumtoxin A</classLabel>
<deletedAxiom>&apos;Nivobotulinumtoxin A&apos; SubClassOf &apos;Bacterial Toxin&apos;</deletedAxiom>
<newAxiom>&apos;Nivobotulinumtoxin A&apos; SubClassOf &apos;Botulinum Toxin&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C111906</classIRI>
<classLabel>Laprituximab Emtansine</classLabel>
<deletedAxiom>&apos;Laprituximab Emtansine&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Laprituximab Emtansine&apos; SubClassOf &apos;EGFR-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Laprituximab Emtansine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201551</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C111902</classIRI>
<classLabel>Lenti-D/ABCD1-transduced Autologous Hematopoietic Stem Cells</classLabel>
<deletedAxiom>&apos;Lenti-D/ABCD1-transduced Autologous Hematopoietic Stem Cells&apos; SubClassOf &apos;Biological Agent&apos;</deletedAxiom>
<newAxiom>&apos;Lenti-D/ABCD1-transduced Autologous Hematopoietic Stem Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159652</classIRI>
<classLabel>Pacanalotamab</classLabel>
<deletedAxiom>&apos;Pacanalotamab&apos; SubClassOf &apos;Anti-BCMA Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Pacanalotamab&apos; SubClassOf &apos;Anti-BCMA/CD3 Bispecific Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62445</classIRI>
<classLabel>Catumaxomab</classLabel>
<deletedAxiom>&apos;Catumaxomab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Catumaxomab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62483</classIRI>
<classLabel>Amatuximab</classLabel>
<deletedAxiom>&apos;Amatuximab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Amatuximab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201534</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62510</classIRI>
<classLabel>Mogamulizumab</classLabel>
<newAxiom>&apos;Mogamulizumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62528</classIRI>
<classLabel>Blinatumomab</classLabel>
<deletedAxiom>&apos;Blinatumomab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Blinatumomab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159407</classIRI>
<classLabel>Botulinum Toxin E EB-001</classLabel>
<deletedAxiom>&apos;Botulinum Toxin E EB-001&apos; SubClassOf &apos;Bacterial Toxin&apos;</deletedAxiom>
<newAxiom>&apos;Botulinum Toxin E EB-001&apos; SubClassOf &apos;Botulinum Toxin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198987</classIRI>
<classLabel>Anti-PVRIG Monoclonal Antibody JS009</classLabel>
<deletedAxiom>&apos;Anti-PVRIG Monoclonal Antibody JS009&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PVRIG Monoclonal Antibody JS009&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201512</newAxiom>
<newAxiom>&apos;Anti-PVRIG Monoclonal Antibody JS009&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C184369</classIRI>
<classLabel>Anti-CD38/CD3 Bispecific Monoclonal Antibody XmAb18968</classLabel>
<deletedAxiom>&apos;Anti-CD38/CD3 Bispecific Monoclonal Antibody XmAb18968&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD38/CD3 Bispecific Monoclonal Antibody XmAb18968&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C184368</classIRI>
<classLabel>Anti-c-Met ADC ABBV-400</classLabel>
<deletedAxiom>&apos;Anti-c-Met ADC ABBV-400&apos; SubClassOf &apos;c-Met-targeting Agent&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-c-Met ADC ABBV-400&apos; SubClassOf &apos;Immunoconjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-c-Met ADC ABBV-400&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201552</newAxiom>
</changedClass>
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<classLabel>Spanlecortemlocel</classLabel>
<deletedAxiom>&apos;Spanlecortemlocel&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Spanlecortemlocel&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Vobramitamab Duocarmazine</classLabel>
<deletedAxiom>&apos;Vobramitamab Duocarmazine&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Vobramitamab Duocarmazine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201516</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198701</classIRI>
<classLabel>Anti-DLL3 Bispecific Antibody RO7616789</classLabel>
<newAxiom>&apos;Anti-DLL3 Bispecific Antibody RO7616789&apos; SubClassOf &apos;Anti-CD137 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198878</classIRI>
<classLabel>Anti-CD19/CD20 Bicistronic CAR T-cells</classLabel>
<deletedAxiom>&apos;Anti-CD19/CD20 Bicistronic CAR T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD19/CD20 Bicistronic CAR T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Allogeneic Natural Killer Cells CHM 0201</classLabel>
<deletedAxiom>&apos;Allogeneic Natural Killer Cells CHM 0201&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic Natural Killer Cells CHM 0201&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185289</classIRI>
<classLabel>CBL-B Inhibitor-treated Autologous Tumor-infiltrating Lymphocytes DeTIL-0255</classLabel>
<deletedAxiom>&apos;CBL-B Inhibitor-treated Autologous Tumor-infiltrating Lymphocytes DeTIL-0255&apos; SubClassOf &apos;Therapeutic Tumor Infiltrating Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;CBL-B Inhibitor-treated Autologous Tumor-infiltrating Lymphocytes DeTIL-0255&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
<newAxiom>&apos;CBL-B Inhibitor-treated Autologous Tumor-infiltrating Lymphocytes DeTIL-0255&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Autologous CISH-inactivated TILs</classLabel>
<deletedAxiom>&apos;Autologous CISH-inactivated TILs&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Autologous CISH-inactivated TILs&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199972</classIRI>
<classLabel>Histoplasma capsulatum, Mycelial Phase</classLabel>
<deletedAxiom>&apos;Histoplasma capsulatum, Mycelial Phase&apos; SubClassOf &apos;Histoplasma capsulatum&apos;</deletedAxiom>
<newAxiom>&apos;Histoplasma capsulatum, Mycelial Phase&apos; SubClassOf &apos;Histoplasma capsulatus&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Histoplasma capsulatus</classLabel>
<deletedAxiom>&apos;Histoplasma capsulatus&apos; SubClassOf &apos;Cryptococcus&apos;</deletedAxiom>
<newAxiom>&apos;Histoplasma capsulatus&apos; SubClassOf &apos;Histoplasma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199973</classIRI>
<classLabel>Histoplasma capsulatum, Yeast Phase</classLabel>
<deletedAxiom>&apos;Histoplasma capsulatum, Yeast Phase&apos; SubClassOf &apos;Histoplasma capsulatum&apos;</deletedAxiom>
<newAxiom>&apos;Histoplasma capsulatum, Yeast Phase&apos; SubClassOf &apos;Histoplasma capsulatus&apos;</newAxiom>
</changedClass>
<changedClass>
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<newAxiom>&apos;Autologous Anti-Muc1/CD33/CD38/CD56/CD123 Gene-engineered CAR-T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201493</newAxiom>
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<classLabel>Sizavaleucel</classLabel>
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<newAxiom>&apos;Sizavaleucel&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
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<classLabel>GJB2 Gene</classLabel>
<newAxiom>&apos;GJB2 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Intercellular Communication Process&apos;</newAxiom>
<newAxiom>&apos;GJB2 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Intercellular Transport Process&apos;</newAxiom>
<newAxiom>&apos;GJB2 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Transmembrane Transport&apos;</newAxiom>
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<newAxiom>&apos;Anti-CD19/CD20/CD22/CD30 CAR-T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</newAxiom>
<newAxiom>&apos;Anti-CD19/CD20/CD22/CD30 CAR-T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201513</newAxiom>
<newAxiom>&apos;Anti-CD19/CD20/CD22/CD30 CAR-T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201173</newAxiom>
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<classLabel>Colorectal Cribriform Comedo-Type Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Colorectal Cribriform Comedo-Type Adenocarcinoma&apos; EquivalentTo &apos;Cribriform Carcinoma&apos; and &apos;Comedocarcinoma&apos; and &apos;Colorectal Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Cribriform Pattern&apos;)</deletedAxiom>
<newAxiom>&apos;Colorectal Cribriform Comedo-Type Adenocarcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201124 and &apos;Cribriform Carcinoma&apos; and &apos;Colorectal Adenocarcinoma&apos;</newAxiom>
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<classLabel>Autologous Anti-CD19/CD20 Bispecific CAR-T Cells IMPT-314</classLabel>
<newAxiom>&apos;Autologous Anti-CD19/CD20 Bispecific CAR-T Cells IMPT-314&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</newAxiom>
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<classLabel>Muscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 4</classLabel>
<newAxiom>&apos;Muscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 4&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201161</newAxiom>
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<classLabel>Muscular Dystrophy-Dystroglycanopathy (Limb-Girdle) Type C, 5</classLabel>
<newAxiom>&apos;Muscular Dystrophy-Dystroglycanopathy (Limb-Girdle) Type C, 5&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201165</newAxiom>
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<changedClass>
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<classLabel>Progenitor B-Lymphocyte to Total Cells Ratio Measurement</classLabel>
<deletedAxiom>&apos;Progenitor B-Lymphocyte to Total Cells Ratio Measurement&apos; SubClassOf &apos;Lymphocyte to Total Cell Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Progenitor B-Lymphocyte to Total Cells Ratio Measurement&apos; SubClassOf &apos;B-Lymphocyte to Total Cells Ratio Measurement&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199611</classIRI>
<classLabel>Anti-CD161 Monoclonal Antibody IMT-009</classLabel>
<newAxiom>&apos;Anti-CD161 Monoclonal Antibody IMT-009&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199622</classIRI>
<classLabel>Allogeneic Anti-CD33 CAR-NK Cells QN-023a</classLabel>
<deletedAxiom>&apos;Allogeneic Anti-CD33 CAR-NK Cells QN-023a&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic Anti-CD33 CAR-NK Cells QN-023a&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126651</classIRI>
<classLabel>Progressive Familial Heart Block, Type Ia</classLabel>
<deletedAxiom>&apos;Progressive Familial Heart Block, Type Ia&apos; SubClassOf &apos;Arrhythmia&apos;</deletedAxiom>
<newAxiom>&apos;Progressive Familial Heart Block, Type Ia&apos; SubClassOf &apos;Cardiac Conduction Disorder&apos;</newAxiom>
<newAxiom>&apos;Progressive Familial Heart Block, Type Ia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SCN5A Gene&apos;</newAxiom>
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<changedClass>
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<classLabel>Anti-PD-1/Anti-CD3 Bispecific Antibody ONO-4685</classLabel>
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<deletedAxiom>&apos;Anti-PD-1/Anti-CD3 Bispecific Antibody ONO-4685&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PD-1/Anti-CD3 Bispecific Antibody ONO-4685&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
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<changedClass>
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<classLabel>Autologous Anti-HER2 CAR-CD28 T Cells</classLabel>
<newAxiom>&apos;Autologous Anti-HER2 CAR-CD28 T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201497</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185169</classIRI>
<classLabel>Autologous Anti-CD7-CAR-CD28zeta T-cells</classLabel>
<newAxiom>&apos;Autologous Anti-CD7-CAR-CD28zeta T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201177</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199718</classIRI>
<classLabel>Gut-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic Central Memory T-Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;Gut-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic Central Memory T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<deletedAxiom>&apos;Gut-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic Central Memory T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Gut-Homing Cytotoxic Central Memory T-Lymphocyte Count&apos;</deletedAxiom>
<newAxiom>&apos;Gut-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic Central Memory T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Central Memory Cytotoxic T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199717</classIRI>
<classLabel>Gut-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;Gut-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Gut-Homing Cytotoxic Central Memory T-Lymphocyte Count&apos;</deletedAxiom>
<deletedAxiom>&apos;Gut-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Gut-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Central Memory Cytotoxic T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Skin-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic Central Memory T-Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;Skin-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic Central Memory T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<deletedAxiom>&apos;Skin-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic Central Memory T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Central Memory Cytotoxic T-Lymphocyte Count&apos;</deletedAxiom>
<newAxiom>&apos;Skin-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic Central Memory T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Central Memory Cytotoxic T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Skin-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;Skin-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<deletedAxiom>&apos;Skin-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Central Memory Cytotoxic T-Lymphocyte Count&apos;</deletedAxiom>
<newAxiom>&apos;Skin-Homing Cytotoxic Central Memory T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Central Memory Cytotoxic T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement&apos;</newAxiom>
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<changedClass>
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<classLabel>Anti-CD19-CAR-CD3zeta-4-1BB-Expressing Allogenic Natural Killer Cells</classLabel>
<deletedAxiom>&apos;Anti-CD19-CAR-CD3zeta-4-1BB-Expressing Allogenic Natural Killer Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD19-CAR-CD3zeta-4-1BB-Expressing Allogenic Natural Killer Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
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<changedClass>
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<classLabel>Eurestobart</classLabel>
<deletedAxiom>&apos;Eurestobart&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Eurestobart&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201164</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185128</classIRI>
<classLabel>Anti-B7-H4/Anti-CD3 Bispecific Antibody PF-07260437</classLabel>
<deletedAxiom>&apos;Anti-B7-H4/Anti-CD3 Bispecific Antibody PF-07260437&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-B7-H4/Anti-CD3 Bispecific Antibody PF-07260437&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-B7-H4/Anti-CD3 Bispecific Antibody PF-07260437&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
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<changedClass>
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<classLabel>Allogeneic CD56-positive CD3-negative Natural Killer Cells</classLabel>
<deletedAxiom>&apos;Allogeneic CD56-positive CD3-negative Natural Killer Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic CD56-positive CD3-negative Natural Killer Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199432</classIRI>
<classLabel>Anti-B7-H4/Anti-CD3 Bispecific Antibody GEN1047</classLabel>
<deletedAxiom>&apos;Anti-B7-H4/Anti-CD3 Bispecific Antibody GEN1047&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-B7-H4/Anti-CD3 Bispecific Antibody GEN1047&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-B7-H4/Anti-CD3 Bispecific Antibody GEN1047&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199466</classIRI>
<classLabel>Allogeneic Skin-derived ABCB5-positive MSCs allo-APZ2-OTS</classLabel>
<newAxiom>&apos;Allogeneic Skin-derived ABCB5-positive MSCs allo-APZ2-OTS&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201556</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199468</classIRI>
<classLabel>Autologous Base Edited CD34+ HSPCs BEAM-101</classLabel>
<deletedAxiom>&apos;Autologous Base Edited CD34+ HSPCs BEAM-101&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Base Edited CD34+ HSPCs BEAM-101&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96799</classIRI>
<classLabel>Vantictumab</classLabel>
<newAxiom>&apos;Vantictumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199255</classIRI>
<classLabel>Anti-c-Met/MMAE ADC MYTX-011</classLabel>
<deletedAxiom>&apos;Anti-c-Met/MMAE ADC MYTX-011&apos; SubClassOf &apos;c-Met-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-c-Met/MMAE ADC MYTX-011&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201552</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199290</classIRI>
<classLabel>Autologous Tumor Infiltrating Lymphocytes C-TIL051</classLabel>
<deletedAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes C-TIL051&apos; SubClassOf &apos;Therapeutic Tumor Infiltrating Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes C-TIL051&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
<newAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes C-TIL051&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
</changedClass>
<changedClass>
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<classLabel>ADC MHB088C</classLabel>
<deletedAxiom>&apos;ADC MHB088C&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;ADC MHB088C&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201516</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82351</classIRI>
<classLabel>M87o-Transduced CD34+ Peripheral Blood Stem Cells</classLabel>
<deletedAxiom>&apos;M87o-Transduced CD34+ Peripheral Blood Stem Cells&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;M87o-Transduced CD34+ Peripheral Blood Stem Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201557</newAxiom>
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<changedClass>
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<classLabel>Adecatumumab</classLabel>
<deletedAxiom>&apos;Adecatumumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Adecatumumab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201523</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82348</classIRI>
<classLabel>Onartuzumab</classLabel>
<deletedAxiom>&apos;Onartuzumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Onartuzumab&apos; SubClassOf &apos;Anti-c-Met Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96928</classIRI>
<classLabel>Gallbladder Goblet Cell Carcinoid</classLabel>
<deletedAxiom>&apos;Gallbladder Goblet Cell Carcinoid&apos; EquivalentTo &apos;Combined Carcinoid and Adenocarcinoma&apos; and &apos;Gallbladder Mixed Adenoneuroendocrine Carcinoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Signet Ring Adenocarcinoma Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Chromogranin-A Positive Neoplastic Cells Present&apos;)</deletedAxiom>
<newAxiom>&apos;Gallbladder Goblet Cell Carcinoid&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201135 and &apos;Gallbladder Neuroendocrine Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Chromogranin-A Positive Neoplastic Cells Present&apos;)</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Anti-B7-H3 CAR T-cells</classLabel>
<deletedAxiom>&apos;Anti-B7-H3 CAR T-cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-B7-H3 CAR T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Anti-B7-H3 CAR T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201492</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Anti-CLL1/Anti-CD33 CAR-T Cells LCAR-AMDR</classLabel>
<deletedAxiom>&apos;Anti-CLL1/Anti-CD33 CAR-T Cells LCAR-AMDR&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CLL1/Anti-CD33 CAR-T Cells LCAR-AMDR&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CLL1/Anti-CD33 CAR-T Cells LCAR-AMDR&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201495</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C190955</classIRI>
<classLabel>Autologous ALPG/ALPP-targeted Anti-MSLN CAR-Fas/PTPN2 shRNA-miR-expressing T-lymphocytes AB-1015</classLabel>
<newAxiom>&apos;Autologous ALPG/ALPP-targeted Anti-MSLN CAR-Fas/PTPN2 shRNA-miR-expressing T-lymphocytes AB-1015&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201275</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Trovocabtagene Autoleucel</classLabel>
<deletedAxiom>&apos;Trovocabtagene Autoleucel&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<deletedAxiom>&apos;Trovocabtagene Autoleucel&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Trovocabtagene Autoleucel&apos; SubClassOf &apos;Autologous CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199018</classIRI>
<classLabel>Tinocabtagene Autoleucel</classLabel>
<deletedAxiom>&apos;Tinocabtagene Autoleucel&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<deletedAxiom>&apos;Tinocabtagene Autoleucel&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Tinocabtagene Autoleucel&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Tinocabtagene Autoleucel&apos; SubClassOf &apos;Autologous CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199061</classIRI>
<classLabel>Inaticabtagene Autoleucel</classLabel>
<newAxiom>&apos;Inaticabtagene Autoleucel&apos; SubClassOf &apos;Autologous CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165684</classIRI>
<classLabel>Livmoniplimab</classLabel>
<deletedAxiom>&apos;Livmoniplimab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Livmoniplimab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201536</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199003</classIRI>
<classLabel>Anitocabtagene Autoleucel</classLabel>
<deletedAxiom>&apos;Anitocabtagene Autoleucel&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anitocabtagene Autoleucel&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Anitocabtagene Autoleucel&apos; SubClassOf &apos;Autologous CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C199006</classIRI>
<classLabel>Durcabtagene Autoleucel</classLabel>
<deletedAxiom>&apos;Durcabtagene Autoleucel&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Durcabtagene Autoleucel&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Durcabtagene Autoleucel&apos; SubClassOf &apos;Autologous CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C190688</classIRI>
<classLabel>Anti-CD39 Monoclonal Antibody JS019</classLabel>
<deletedAxiom>&apos;Anti-CD39 Monoclonal Antibody JS019&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD39 Monoclonal Antibody JS019&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201164</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82688</classIRI>
<classLabel>Umbilical Cord Blood-Derived Mesenchymal Stem Cells</classLabel>
<deletedAxiom>&apos;Umbilical Cord Blood-Derived Mesenchymal Stem Cells&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Umbilical Cord Blood-Derived Mesenchymal Stem Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201556</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165774</classIRI>
<classLabel>Anti-CD19-CAR-CD28/CD20-CAR-4-1BB-expressing Autologous T-lymphocytes Hu1928-Hu20BB</classLabel>
<newAxiom>&apos;Anti-CD19-CAR-CD28/CD20-CAR-4-1BB-expressing Autologous T-lymphocytes Hu1928-Hu20BB&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82623</classIRI>
<classLabel>Botulinum Toxin Type A</classLabel>
<deletedAxiom>&apos;Botulinum Toxin Type A&apos; SubClassOf &apos;Bacterial Toxin&apos;</deletedAxiom>
<newAxiom>&apos;Botulinum Toxin Type A&apos; SubClassOf &apos;Botulinum Toxin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126102</classIRI>
<classLabel>Chimeric Antigen Receptor T-Cell Therapy</classLabel>
<deletedAxiom>&apos;Chimeric Antigen Receptor T-Cell Therapy&apos; SubClassOf &apos;Cellular Therapy&apos;</deletedAxiom>
<deletedAxiom>&apos;Chimeric Antigen Receptor T-Cell Therapy&apos; SubClassOf &apos;Adoptive Immunotherapy&apos;</deletedAxiom>
<newAxiom>&apos;Chimeric Antigen Receptor T-Cell Therapy&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201285</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C190717</classIRI>
<classLabel>Anti-CD137/Anti-FAP Bispecific Antibody BI 765179</classLabel>
<newAxiom>&apos;Anti-CD137/Anti-FAP Bispecific Antibody BI 765179&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165750</classIRI>
<classLabel>Autologous CD34-positive Peripheral Blood Stem Cells</classLabel>
<deletedAxiom>&apos;Autologous CD34-positive Peripheral Blood Stem Cells&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Autologous CD34-positive Peripheral Blood Stem Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201557</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C190707</classIRI>
<classLabel>CD19R(EQ)-CD28-CD3zeta-EGFRt-expressing T-lymphocytes</classLabel>
<deletedAxiom>&apos;CD19R(EQ)-CD28-CD3zeta-EGFRt-expressing T-lymphocytes&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165434</classIRI>
<classLabel>Autologous gamma-globinG16D/sh RNA734 Gene-transduced CD34-positive Cells CSL200</classLabel>
<deletedAxiom>&apos;Autologous gamma-globinG16D/sh RNA734 Gene-transduced CD34-positive Cells CSL200&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Autologous gamma-globinG16D/sh RNA734 Gene-transduced CD34-positive Cells CSL200&apos; SubClassOf &apos;Genetically Engineered Hematopoietic Stem Progenitor Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165435</classIRI>
<classLabel>Autologous CD123CAR-CD28-CD3zeta-EGFRt-expressing T Lymphocytes MB-102</classLabel>
<newAxiom>&apos;Autologous CD123CAR-CD28-CD3zeta-EGFRt-expressing T Lymphocytes MB-102&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201493</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165588</classIRI>
<classLabel>Vepsitamab</classLabel>
<deletedAxiom>&apos;Vepsitamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Vepsitamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165551</classIRI>
<classLabel>Anti-CD19 CAR T-cells XLCART001</classLabel>
<deletedAxiom>&apos;Anti-CD19 CAR T-cells XLCART001&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165275</classIRI>
<classLabel>Lymphodepletion Therapy</classLabel>
<deletedAxiom>&apos;Lymphodepletion Therapy&apos; SubClassOf &apos;Therapeutic Procedure&apos;</deletedAxiom>
<newAxiom>&apos;Lymphodepletion Therapy&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201130</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Solid Pseudopapillary Neoplasm of the Ovary</classLabel>
<deletedAxiom>&apos;Solid Pseudopapillary Neoplasm of the Ovary&apos; EquivalentTo &apos;Malignant Ovarian Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Ovary&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lobulated Growth Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Pseudopapillary Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Low Grade Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Cystic Change&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Low Grade&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CTNNB1 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CTNNB1 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Solid Pseudopapillary Neoplasm of the Ovary&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201136 and &apos;Malignant Ovarian Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Ovary&apos;)</newAxiom>
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<changedClass>
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<classLabel>Anti-BTN1A1 Monoclonal Antibody hSTC810</classLabel>
<newAxiom>&apos;Anti-BTN1A1 Monoclonal Antibody hSTC810&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131901</classIRI>
<classLabel>Membrane-bound Interleukin-21-Expanded Haploidentical Natural Killer Cells</classLabel>
<deletedAxiom>&apos;Membrane-bound Interleukin-21-Expanded Haploidentical Natural Killer Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Membrane-bound Interleukin-21-Expanded Haploidentical Natural Killer Cells&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</newAxiom>
<newAxiom>&apos;Membrane-bound Interleukin-21-Expanded Haploidentical Natural Killer Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C190298</classIRI>
<classLabel>C7R-expressing EBVSTs</classLabel>
<deletedAxiom>&apos;C7R-expressing EBVSTs&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;C7R-expressing EBVSTs&apos; SubClassOf &apos;Genetically-engineered Immune Cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179913</classIRI>
<classLabel>Anti-CCR8 Monoclonal Antibody BMS-986340</classLabel>
<newAxiom>&apos;Anti-CCR8 Monoclonal Antibody BMS-986340&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179647</classIRI>
<classLabel>Anti-PSMA/Anti-CD3 T-cell Engaging Bispecific Antibody TNB-585</classLabel>
<deletedAxiom>&apos;Anti-PSMA/Anti-CD3 T-cell Engaging Bispecific Antibody TNB-585&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA/Anti-CD3 T-cell Engaging Bispecific Antibody TNB-585&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA/Anti-CD3 T-cell Engaging Bispecific Antibody TNB-585&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PSMA/Anti-CD3 T-cell Engaging Bispecific Antibody TNB-585&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
<newAxiom>&apos;Anti-PSMA/Anti-CD3 T-cell Engaging Bispecific Antibody TNB-585&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201543</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179637</classIRI>
<classLabel>Anti-PD-L1/Anti-4-1BB Bispecific Antibody ABL503</classLabel>
<newAxiom>&apos;Anti-PD-L1/Anti-4-1BB Bispecific Antibody ABL503&apos; SubClassOf &apos;Anti-CD137 Monoclonal Antibody&apos;</newAxiom>
<newAxiom>&apos;Anti-PD-L1/Anti-4-1BB Bispecific Antibody ABL503&apos; SubClassOf &apos;Anti-PD-L1 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179636</classIRI>
<classLabel>TBX-4000-treated Hematopoietic Stem Cells TBX-2400</classLabel>
<deletedAxiom>&apos;TBX-4000-treated Hematopoietic Stem Cells TBX-2400&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;TBX-4000-treated Hematopoietic Stem Cells TBX-2400&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179630</classIRI>
<classLabel>Allogeneic Anti-CD7 CAR T Cells</classLabel>
<newAxiom>&apos;Allogeneic Anti-CD7 CAR T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201177</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179621</classIRI>
<classLabel>HER-2/PD-L1-targeting CAR-T Cells</classLabel>
<deletedAxiom>&apos;HER-2/PD-L1-targeting CAR-T Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;HER-2/PD-L1-targeting CAR-T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201497</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179629</classIRI>
<classLabel>A2AR Antagonist EXS21546</classLabel>
<deletedAxiom>&apos;A2AR Antagonist EXS21546&apos; SubClassOf &apos;Immunostimulant&apos;</deletedAxiom>
<newAxiom>&apos;A2AR Antagonist EXS21546&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201170</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179618</classIRI>
<classLabel>Anti-TNFR2 Monoclonal Antibody BI-1808</classLabel>
<deletedAxiom>&apos;Anti-TNFR2 Monoclonal Antibody BI-1808&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-TNFR2 Monoclonal Antibody BI-1808&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201522</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179678</classIRI>
<classLabel>Oncolytic Adenovirus ICOVIR5-infected Allogeneic Mesenchymal Stem Cells</classLabel>
<newAxiom>&apos;Oncolytic Adenovirus ICOVIR5-infected Allogeneic Mesenchymal Stem Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201556</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179662</classIRI>
<classLabel>Anti-ROR1/CD3 T-cell Engager NVG-111</classLabel>
<deletedAxiom>&apos;Anti-ROR1/CD3 T-cell Engager NVG-111&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-ROR1/CD3 T-cell Engager NVG-111&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179715</classIRI>
<classLabel>Allogeneic Natural Killer Cells SAR445419</classLabel>
<deletedAxiom>&apos;Allogeneic Natural Killer Cells SAR445419&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic Natural Killer Cells SAR445419&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C190115</classIRI>
<classLabel>Autologous Anti-PSMA CAR/CD2/dnTGF-BRII/PD-1:CD28 Switch Receptor-expressing T-cells TmPSMA-02</classLabel>
<newAxiom>&apos;Autologous Anti-PSMA CAR/CD2/dnTGF-BRII/PD-1:CD28 Switch Receptor-expressing T-cells TmPSMA-02&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201178</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C190116</classIRI>
<classLabel>Autologous Tumor Infiltrating Lymphocytes C-TIL052A</classLabel>
<deletedAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes C-TIL052A&apos; SubClassOf &apos;Therapeutic Tumor Infiltrating Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes C-TIL052A&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
<newAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes C-TIL052A&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C190113</classIRI>
<classLabel>CD19-targeted CAR T Cells BZ019</classLabel>
<deletedAxiom>&apos;CD19-targeted CAR T Cells BZ019&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165166</classIRI>
<classLabel>Imvotamab</classLabel>
<deletedAxiom>&apos;Imvotamab&apos; SubClassOf &apos;Anti-CD20 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Imvotamab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Imvotamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Imvotamab&apos; SubClassOf &apos;Anti-CD20/Anti-CD3 Bispecific Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18947</classIRI>
<classLabel>RNA Polyadenylation</classLabel>
<deletedAxiom>&apos;RNA Polyadenylation&apos; SubClassOf &apos;Biological_Process_Is_Part_Of_Process&apos; some &apos;RNA Processing&apos;</deletedAxiom>
<deletedAxiom>&apos;RNA Polyadenylation&apos; SubClassOf &apos;RNA Synthesis&apos;</deletedAxiom>
<newAxiom>&apos;RNA Polyadenylation&apos; SubClassOf &apos;RNA Processing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C154281</classIRI>
<classLabel>Autologous Anti-HER2-CAR-4-1BB-CD3zeta-CD19t+-expressing Tcm-enriched T-lymphocytes</classLabel>
<newAxiom>&apos;Autologous Anti-HER2-CAR-4-1BB-CD3zeta-CD19t+-expressing Tcm-enriched T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201497</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120552</classIRI>
<classLabel>Lifileucel</classLabel>
<deletedAxiom>&apos;Lifileucel&apos; SubClassOf &apos;Therapeutic Tumor Infiltrating Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Lifileucel&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
<newAxiom>&apos;Lifileucel&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
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<changedClass>
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<classLabel>Glycooptimized Trastuzumab-GEX</classLabel>
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<newAxiom>&apos;Glycooptimized Trastuzumab-GEX&apos; SubClassOf &apos;Anti-HER2 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97943</classIRI>
<classLabel>Namilumab</classLabel>
<deletedAxiom>&apos;Namilumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Namilumab&apos; SubClassOf &apos;Anti-GM-CSF Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174473</classIRI>
<classLabel>FUS/KLF17 Fusion Gene</classLabel>
<deletedAxiom>&apos;FUS/KLF17 Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<newAxiom>&apos;FUS/KLF17 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174474</classIRI>
<classLabel>EWSR1/KLF17 Fusion Gene</classLabel>
<deletedAxiom>&apos;EWSR1/KLF17 Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<newAxiom>&apos;EWSR1/KLF17 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174412</classIRI>
<classLabel>BCMA-CD19 Compound CAR T Cells</classLabel>
<deletedAxiom>&apos;BCMA-CD19 Compound CAR T Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174410</classIRI>
<classLabel>Casdozokitug</classLabel>
<newAxiom>&apos;Casdozokitug&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174413</classIRI>
<classLabel>BCMA CART Cells Secreting Mutant PD-1Fc Fusion Protein</classLabel>
<deletedAxiom>&apos;BCMA CART Cells Secreting Mutant PD-1Fc Fusion Protein&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188792</classIRI>
<classLabel>T-cell-redirecting Antibody JNJ-80948543</classLabel>
<deletedAxiom>&apos;T-cell-redirecting Antibody JNJ-80948543&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;T-cell-redirecting Antibody JNJ-80948543&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174128</classIRI>
<classLabel>Multi-antigen-directed Autologous T-cells NEXI-002</classLabel>
<deletedAxiom>&apos;Multi-antigen-directed Autologous T-cells NEXI-002&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Multi-antigen-directed Autologous T-cells NEXI-002&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188715</classIRI>
<classLabel>CDISC DDF Study Data Attribute Terminology</classLabel>
<deletedAxiom>&apos;CDISC DDF Study Data Attribute Terminology&apos; SubClassOf &apos;CDISC DDF Terminology&apos;</deletedAxiom>
<newAxiom>&apos;CDISC DDF Study Data Attribute Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188717</classIRI>
<classLabel>CDISC DDF Workflow Attribute Terminology</classLabel>
<deletedAxiom>&apos;CDISC DDF Workflow Attribute Terminology&apos; SubClassOf &apos;CDISC DDF Terminology&apos;</deletedAxiom>
<newAxiom>&apos;CDISC DDF Workflow Attribute Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115969</classIRI>
<classLabel>Hsp70-peptide TKD/IL-2-activated Autologous Natural Killer Cells</classLabel>
<deletedAxiom>&apos;Hsp70-peptide TKD/IL-2-activated Autologous Natural Killer Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Hsp70-peptide TKD/IL-2-activated Autologous Natural Killer Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
<newAxiom>&apos;Hsp70-peptide TKD/IL-2-activated Autologous Natural Killer Cells&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101288</classIRI>
<classLabel>RalA-Binding Protein 1</classLabel>
<deletedAxiom>&apos;RalA-Binding Protein 1&apos; EquivalentTo &apos;GTPase-Activating Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Rac1 Cell Motility Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Ras Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Pancreatic Cancer Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Chemotactic Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RALBP1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;RalA-Binding Protein 1&apos; EquivalentTo &apos;Translocase&apos; and &apos;GTPase-Activating Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Rac1 Cell Motility Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Ras Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Pancreatic Cancer Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Chemotactic Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RALBP1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101286</classIRI>
<classLabel>RALBP1 Gene</classLabel>
<newAxiom>&apos;RALBP1 Gene&apos; SubClassOf &apos;Translocase Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174222</classIRI>
<classLabel>CDISC Protocol Study Arm Type Value Set Terminology</classLabel>
<newAxiom>&apos;CDISC Protocol Study Arm Type Value Set Terminology&apos; SubClassOf &apos;CDISC DDF Terminology&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188827</classIRI>
<classLabel>Study Arm Type Name</classLabel>
<deletedAxiom>&apos;Study Arm Type Name&apos; SubClassOf &apos;Name&apos;</deletedAxiom>
<newAxiom>&apos;Study Arm Type Name&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188800</classIRI>
<classLabel>Autologous Anti-GD2/Anti-PSMA 4SCAR-expressing Bispecific T-cells</classLabel>
<newAxiom>&apos;Autologous Anti-GD2/Anti-PSMA 4SCAR-expressing Bispecific T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201178</newAxiom>
<newAxiom>&apos;Autologous Anti-GD2/Anti-PSMA 4SCAR-expressing Bispecific T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201491</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188804</classIRI>
<classLabel>Anti-GD2/Anti-CD70 4SCAR-expressing Bispecific T-cells</classLabel>
<deletedAxiom>&apos;Anti-GD2/Anti-CD70 4SCAR-expressing Bispecific T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-GD2/Anti-CD70 4SCAR-expressing Bispecific T-cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anti-GD2/Anti-CD70 4SCAR-expressing Bispecific T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201176</newAxiom>
<newAxiom>&apos;Anti-GD2/Anti-CD70 4SCAR-expressing Bispecific T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201491</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188801</classIRI>
<classLabel>Anti-GD2/Anti-CD56 4SCAR-expressing Bispecific T-cells</classLabel>
<deletedAxiom>&apos;Anti-GD2/Anti-CD56 4SCAR-expressing Bispecific T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Anti-GD2/Anti-CD56 4SCAR-expressing Bispecific T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201491</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188802</classIRI>
<classLabel>Anti-PSMA/Anti-CD70 4SCAR-expressing Bispecific T-cells</classLabel>
<deletedAxiom>&apos;Anti-PSMA/Anti-CD70 4SCAR-expressing Bispecific T-cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA/Anti-CD70 4SCAR-expressing Bispecific T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PSMA/Anti-CD70 4SCAR-expressing Bispecific T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201178</newAxiom>
<newAxiom>&apos;Anti-PSMA/Anti-CD70 4SCAR-expressing Bispecific T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201176</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C140552</classIRI>
<classLabel>Anti-PSMA/PBD ADC MEDI3726</classLabel>
<deletedAxiom>&apos;Anti-PSMA/PBD ADC MEDI3726&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA/PBD ADC MEDI3726&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PSMA/PBD ADC MEDI3726&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201544</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174011</classIRI>
<classLabel>Allogeneic PD-L1 Tumor-targeted High-affinity Natural Killer Cells</classLabel>
<deletedAxiom>&apos;Allogeneic PD-L1 Tumor-targeted High-affinity Natural Killer Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic PD-L1 Tumor-targeted High-affinity Natural Killer Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101055</classIRI>
<classLabel>FUS/CREB3L1 Fusion Gene</classLabel>
<deletedAxiom>&apos;FUS/CREB3L1 Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<newAxiom>&apos;FUS/CREB3L1 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188359</classIRI>
<classLabel>Anti-ENPP3/Anti-CD3 Bispecific Antibody XmAb819</classLabel>
<deletedAxiom>&apos;Anti-ENPP3/Anti-CD3 Bispecific Antibody XmAb819&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-ENPP3/Anti-CD3 Bispecific Antibody XmAb819&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-ENPP3/Anti-CD3 Bispecific Antibody XmAb819&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188358</classIRI>
<classLabel>Autologous Anti-CD20CAR-CD28-4-1BB-CD3zeta T-lymphocytes MB-106</classLabel>
<newAxiom>&apos;Autologous Anti-CD20CAR-CD28-4-1BB-CD3zeta T-lymphocytes MB-106&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188374</classIRI>
<classLabel>Trained Immunity Natural Killer Cells IBR900</classLabel>
<deletedAxiom>&apos;Trained Immunity Natural Killer Cells IBR900&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Trained Immunity Natural Killer Cells IBR900&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129936</classIRI>
<classLabel>Anti-Glypican 3/CD3 Bispecific Antibody ERY974</classLabel>
<deletedAxiom>&apos;Anti-Glypican 3/CD3 Bispecific Antibody ERY974&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-Glypican 3/CD3 Bispecific Antibody ERY974&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-Glypican 3/CD3 Bispecific Antibody ERY974&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188121</classIRI>
<classLabel>Anti-CD39 Antibody/TGF-beta RII Ectodomain Fusion Protein ES014</classLabel>
<deletedAxiom>&apos;Anti-CD39 Antibody/TGF-beta RII Ectodomain Fusion Protein ES014&apos; SubClassOf &apos;Antineoplastic Immunomodulating Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD39 Antibody/TGF-beta RII Ectodomain Fusion Protein ES014&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201133</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188123</classIRI>
<classLabel>BCMA-targeted LCAR-BCDR Cells</classLabel>
<deletedAxiom>&apos;BCMA-targeted LCAR-BCDR Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129720</classIRI>
<classLabel>Aarskog Syndrome</classLabel>
<newAxiom>&apos;Aarskog Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201158</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115172</classIRI>
<classLabel>Gap Junction Alpha-1 Protein</classLabel>
<deletedAxiom>&apos;Gap Junction Alpha-1 Protein&apos; EquivalentTo &apos;Transport Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Beta-Catenin Accumulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Arrhythmogenic Right Ventricular Cardiomyopathy Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Gap Junction Assembly Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;N-Cadherin Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Gap Junction&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Organogenesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Restricted Diffusion&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;GJA1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Gap Junction Alpha-1 Protein&apos; EquivalentTo &apos;Transport Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Beta-Catenin Accumulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Arrhythmogenic Right Ventricular Cardiomyopathy Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Gap Junction Assembly Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;N-Cadherin Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Gap Junction&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intercellular Communication Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Organogenesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transmembrane Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intercellular Transport Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Restricted Diffusion&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;GJA1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115170</classIRI>
<classLabel>GJA1 Gene</classLabel>
<newAxiom>&apos;GJA1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Transmembrane Transport&apos;</newAxiom>
<newAxiom>&apos;GJA1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Intercellular Transport Process&apos;</newAxiom>
<newAxiom>&apos;GJA1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Intercellular Communication Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115101</classIRI>
<classLabel>Anti-CD19/CD3 Tetravalent Antibody AFM11</classLabel>
<newAxiom>&apos;Anti-CD19/CD3 Tetravalent Antibody AFM11&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188232</classIRI>
<classLabel>Anti-CDH17/Anti-CD3 Bispecific Antibody ARB202</classLabel>
<deletedAxiom>&apos;Anti-CDH17/Anti-CD3 Bispecific Antibody ARB202&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CDH17/Anti-CD3 Bispecific Antibody ARB202&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188233</classIRI>
<classLabel>Autologous Anti-CD7 CAR T-cells SENL101</classLabel>
<newAxiom>&apos;Autologous Anti-CD7 CAR T-cells SENL101&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201177</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188201</classIRI>
<classLabel>Anti-CD33/CD3 Bispecific Antibody</classLabel>
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<newAxiom>&apos;Anti-CD123/Anti-CD3 Bispecific DART Molecule MGD024&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201511</newAxiom>
<newAxiom>&apos;Anti-CD123/Anti-CD3 Bispecific DART Molecule MGD024&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
<newAxiom>&apos;Anti-CD123/Anti-CD3 Bispecific DART Molecule MGD024&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
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<classLabel>Autologous Tumor Infiltrating Lymphocytes LM103</classLabel>
<deletedAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes LM103&apos; SubClassOf &apos;Therapeutic Tumor Infiltrating Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes LM103&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
<newAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes LM103&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
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<changedClass>
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<classLabel>Autologous Anti-B7-H3 CAR T Cells CAR.B7-H3T</classLabel>
<newAxiom>&apos;Autologous Anti-B7-H3 CAR T Cells CAR.B7-H3T&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201492</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Anti-CLDN18.2/Anti-CD3 Bispecific Antibody ASP2138</classLabel>
<deletedAxiom>&apos;Anti-CLDN18.2/Anti-CD3 Bispecific Antibody ASP2138&apos; SubClassOf &apos;Bispecific Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CLDN18.2/Anti-CD3 Bispecific Antibody ASP2138&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CLDN18.2/Anti-CD3 Bispecific Antibody ASP2138&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Anti-CD19-CAR CMV-specific T-lymphocytes</classLabel>
<deletedAxiom>&apos;Anti-CD19-CAR CMV-specific T-lymphocytes&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173153</classIRI>
<classLabel>Allogeneic CRISPR-Cas9 Engineered Anti-CD70 CAR-T Cells CTX130</classLabel>
<newAxiom>&apos;Allogeneic CRISPR-Cas9 Engineered Anti-CD70 CAR-T Cells CTX130&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201176</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148189</classIRI>
<classLabel>Autologous Mesenchymal Stem Cells-Poly Lactic-co-glycolic Acid</classLabel>
<deletedAxiom>&apos;Autologous Mesenchymal Stem Cells-Poly Lactic-co-glycolic Acid&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Mesenchymal Stem Cells-Poly Lactic-co-glycolic Acid&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201556</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187791</classIRI>
<classLabel>Atypical Mononuclear Cells to Leukocytes Ratio Measurement</classLabel>
<deletedAxiom>&apos;Atypical Mononuclear Cells to Leukocytes Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Atypical Mononuclear Cells to Leukocytes Ratio Measurement&apos; SubClassOf &apos;Abnormal Cells to Leukocytes Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187750</classIRI>
<classLabel>Unconventional Class-switched Memory B-Lymphocyte Subpopulation to Unconventional Class-switched Memory B-Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;Unconventional Class-switched Memory B-Lymphocyte Subpopulation to Unconventional Class-switched Memory B-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Unconventional Class-switched Memory B-Lymphocyte Subpopulation to Unconventional Class-switched Memory B-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Memory B-Lymphocytes to Total B-Lymphocytes Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187751</classIRI>
<classLabel>Unconventional Class-switched Memory B-Lymphocyte to B-Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;Unconventional Class-switched Memory B-Lymphocyte to B-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Unconventional Class-switched Memory B-Lymphocyte to B-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Memory B-Lymphocytes to Total B-Lymphocytes Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148141</classIRI>
<classLabel>Tepoditamab</classLabel>
<deletedAxiom>&apos;Tepoditamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Tepoditamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187749</classIRI>
<classLabel>Unconventional Class-switched Memory B-Lymphocyte Subpopulation Count</classLabel>
<newAxiom>&apos;Unconventional Class-switched Memory B-Lymphocyte Subpopulation Count&apos; SubClassOf &apos;Unconventional Class-switched Memory B-Lymphocyte Count&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148135</classIRI>
<classLabel>iC9-GD2-CAR-CD28-OX40-expressing Autologous NKT Cells</classLabel>
<newAxiom>&apos;iC9-GD2-CAR-CD28-OX40-expressing Autologous NKT Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201491</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148133</classIRI>
<classLabel>Autologous PD-1 Antibody-expressing Mesothelin-specific CAR-T Cells</classLabel>
<newAxiom>&apos;Autologous PD-1 Antibody-expressing Mesothelin-specific CAR-T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201275</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187730</classIRI>
<classLabel>Non-class-switched Memory B-Lymphocyte to Total B-Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;Non-class-switched Memory B-Lymphocyte to Total B-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Non-class-switched Memory B-Lymphocyte to Total B-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Memory B-Lymphocytes to Total B-Lymphocytes Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148160</classIRI>
<classLabel>Autologous Mesothelin-specific CAR-T Cells</classLabel>
<newAxiom>&apos;Autologous Mesothelin-specific CAR-T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201275</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187729</classIRI>
<classLabel>Non-class-switched Memory B-Lymphocyte Subpopulation to Total Non-class-switched Memory B-Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;Non-class-switched Memory B-Lymphocyte Subpopulation to Total Non-class-switched Memory B-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Non-class-switched Memory B-Lymphocyte Subpopulation to Total Non-class-switched Memory B-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Memory B-Lymphocytes to Total B-Lymphocytes Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187712</classIRI>
<classLabel>Class-switched Memory B-Lymphocyte Subpopulation to Total B-Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;Class-switched Memory B-Lymphocyte Subpopulation to Total B-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Class-switched Memory B-Lymphocyte Subpopulation to Total B-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Memory B-Lymphocytes to Total B-Lymphocytes Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148149</classIRI>
<classLabel>Allogeneic TCR alpha/beta-positive T-lymphocyte-depleted Peripheral Blood Stem Cells</classLabel>
<deletedAxiom>&apos;Allogeneic TCR alpha/beta-positive T-lymphocyte-depleted Peripheral Blood Stem Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Allogeneic TCR alpha/beta-positive T-lymphocyte-depleted Peripheral Blood Stem Cells&apos; SubClassOf &apos;T-cell Receptor-engineered T-cells&apos;</deletedAxiom>
<deletedAxiom>&apos;Allogeneic TCR alpha/beta-positive T-lymphocyte-depleted Peripheral Blood Stem Cells&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic TCR alpha/beta-positive T-lymphocyte-depleted Peripheral Blood Stem Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201557</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187713</classIRI>
<classLabel>Class-switched Memory B-Lymphocytes Subpopulation to Total Class-switched Memory B-Lymphocytes Ratio Measurement</classLabel>
<deletedAxiom>&apos;Class-switched Memory B-Lymphocytes Subpopulation to Total Class-switched Memory B-Lymphocytes Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Class-switched Memory B-Lymphocytes Subpopulation to Total Class-switched Memory B-Lymphocytes Ratio Measurement&apos; SubClassOf &apos;Memory B-Lymphocytes to Total B-Lymphocytes Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84718</classIRI>
<classLabel>Friedreich Ataxia</classLabel>
<newAxiom>&apos;Friedreich Ataxia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201199</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84783</classIRI>
<classLabel>Immunodeficiency with Hyper-IgM</classLabel>
<newAxiom>&apos;Immunodeficiency with Hyper-IgM&apos; SubClassOf &apos;Hyperimmunoglobulin M Syndrome&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84855</classIRI>
<classLabel>Anti-CD70 Antibody-Drug Conjugate MDX-1203</classLabel>
<deletedAxiom>&apos;Anti-CD70 Antibody-Drug Conjugate MDX-1203&apos; SubClassOf &apos;CD70-targeting Agent&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD70 Antibody-Drug Conjugate MDX-1203&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD70 Antibody-Drug Conjugate MDX-1203&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201550</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187256</classIRI>
<classLabel>Anti-CD39 Monoclonal Antibody PUR001</classLabel>
<deletedAxiom>&apos;Anti-CD39 Monoclonal Antibody PUR001&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD39 Monoclonal Antibody PUR001&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201164</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153885</classIRI>
<classLabel>Allogeneic CD34-positive E-rosetted T-cell Depleted Peripheral Blood Stem Cells</classLabel>
<deletedAxiom>&apos;Allogeneic CD34-positive E-rosetted T-cell Depleted Peripheral Blood Stem Cells&apos; SubClassOf &apos;T-cell Receptor-engineered T-cells&apos;</deletedAxiom>
<deletedAxiom>&apos;Allogeneic CD34-positive E-rosetted T-cell Depleted Peripheral Blood Stem Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Allogeneic CD34-positive E-rosetted T-cell Depleted Peripheral Blood Stem Cells&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic CD34-positive E-rosetted T-cell Depleted Peripheral Blood Stem Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201557</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128896</classIRI>
<classLabel>4SCAR-GD2-modified T-lymphocytes</classLabel>
<deletedAxiom>&apos;4SCAR-GD2-modified T-lymphocytes&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<deletedAxiom>&apos;4SCAR-GD2-modified T-lymphocytes&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;4SCAR-GD2-modified T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201491</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Anti-mesothelin CAR Vector-transduced T-lymphocytes</classLabel>
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<deletedAxiom>&apos;Anti-mesothelin CAR Vector-transduced T-lymphocytes&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Anti-mesothelin CAR Vector-transduced T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201275</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Anti-CLDN6/CD3 BiTE Antibody AMG 794</classLabel>
<deletedAxiom>&apos;Anti-CLDN6/CD3 BiTE Antibody AMG 794&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CLDN6/CD3 BiTE Antibody AMG 794&apos; SubClassOf &apos;Immune Checkpoint Inhibitor&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CLDN6/CD3 BiTE Antibody AMG 794&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CLDN6/CD3 BiTE Antibody AMG 794&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
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<classLabel>Anti-c-Met Antibody-drug Conjugate BYON3521</classLabel>
<deletedAxiom>&apos;Anti-c-Met Antibody-drug Conjugate BYON3521&apos; SubClassOf &apos;c-Met-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-c-Met Antibody-drug Conjugate BYON3521&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201552</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187337</classIRI>
<classLabel>Anti-EGFR/Anti-B7-H3 CAR-T Cells</classLabel>
<deletedAxiom>&apos;Anti-EGFR/Anti-B7-H3 CAR-T Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-EGFR/Anti-B7-H3 CAR-T Cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anti-EGFR/Anti-B7-H3 CAR-T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201175</newAxiom>
<newAxiom>&apos;Anti-EGFR/Anti-B7-H3 CAR-T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201492</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128941</classIRI>
<classLabel>MT-CO1 Gene</classLabel>
<deletedAxiom>&apos;MT-CO1 Gene&apos; SubClassOf &apos;Oxidoreductase Gene&apos;</deletedAxiom>
<newAxiom>&apos;MT-CO1 Gene&apos; SubClassOf &apos;Translocase Gene&apos;</newAxiom>
</changedClass>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128943</classIRI>
<classLabel>Cytochrome C Oxidase Subunit 1</classLabel>
<deletedAxiom>&apos;Cytochrome C Oxidase Subunit 1&apos; EquivalentTo &apos;Oxidoreductase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Alzheimer&apos;s Disease Pathway KEGG&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Huntington&apos;s Disease Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Oxidative Phosphorylation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Parkinson&apos;s Disease Pathway KEGG&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cardiac Muscle Contraction Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Mitochondrial Membrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Mitochondrion&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Inner Mitochondrial Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Electron-Transport Chain of the Respiratory Enzymes&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;All Sites&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Cytochrome C Oxidase&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Respiration&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Nucleotide Metabolic Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;MT-CO1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Cytochrome C Oxidase Subunit 1&apos; EquivalentTo &apos;Translocase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Alzheimer&apos;s Disease Pathway KEGG&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Huntington&apos;s Disease Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Oxidative Phosphorylation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Parkinson&apos;s Disease Pathway KEGG&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cardiac Muscle Contraction Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Mitochondrial Membrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Mitochondrion&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Inner Mitochondrial Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Electron-Transport Chain of the Respiratory Enzymes&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;All Sites&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Cytochrome C Oxidase&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Respiration&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Nucleotide Metabolic Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;MT-CO1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187300</classIRI>
<classLabel>Anti-CD19 CAR T Cells AT101</classLabel>
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<newAxiom>&apos;DNA Repair Protein RAD51 Homolog 2&apos; EquivalentTo &apos;DNA Repair Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Homologous Recombination Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201206) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;DNA Binding Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Homologous Recombination&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Binding&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Recombination Repair&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RAD51B Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181756</classIRI>
<classLabel>Adenosine A2B Receptor Antagonist TT-4</classLabel>
<deletedAxiom>&apos;Adenosine A2B Receptor Antagonist TT-4&apos; SubClassOf &apos;Immunostimulant&apos;</deletedAxiom>
<newAxiom>&apos;Adenosine A2B Receptor Antagonist TT-4&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201171</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181753</classIRI>
<classLabel>Adenosine A2A Receptor Antagonist TT-10</classLabel>
<deletedAxiom>&apos;Adenosine A2A Receptor Antagonist TT-10&apos; SubClassOf &apos;Immunostimulant&apos;</deletedAxiom>
<newAxiom>&apos;Adenosine A2A Receptor Antagonist TT-10&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201170</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156791</classIRI>
<classLabel>Anti-PVRIG Monoclonal Antibody COM701</classLabel>
<deletedAxiom>&apos;Anti-PVRIG Monoclonal Antibody COM701&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PVRIG Monoclonal Antibody COM701&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
<newAxiom>&apos;Anti-PVRIG Monoclonal Antibody COM701&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201512</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Cixutumumab</classLabel>
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<deletedAxiom>&apos;Cixutumumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Cixutumumab&apos; SubClassOf &apos;Anti-IGF1R Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Anti-Her-2-CAR Retroviral Vector-Transduced Autologous Peripheral Blood Lymphocytes</classLabel>
<newAxiom>&apos;Anti-Her-2-CAR Retroviral Vector-Transduced Autologous Peripheral Blood Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201497</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C79809</classIRI>
<classLabel>Defactinib</classLabel>
<deletedAxiom>&apos;Defactinib&apos; SubClassOf &apos;Tyrosine Kinase Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Defactinib&apos; SubClassOf &apos;FAK Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C117238</classIRI>
<classLabel>Flotetuzumab</classLabel>
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<newAxiom>&apos;Flotetuzumab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181804</classIRI>
<classLabel>Allogeneic CD19-OX40-CD3zeta-CAR-mbIL-15-expressing Natural Killer Cells NKX019</classLabel>
<deletedAxiom>&apos;Allogeneic CD19-OX40-CD3zeta-CAR-mbIL-15-expressing Natural Killer Cells NKX019&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic CD19-OX40-CD3zeta-CAR-mbIL-15-expressing Natural Killer Cells NKX019&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
<newAxiom>&apos;Allogeneic CD19-OX40-CD3zeta-CAR-mbIL-15-expressing Natural Killer Cells NKX019&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C117229</classIRI>
<classLabel>Tusamitamab Ravtansine</classLabel>
<deletedAxiom>&apos;Tusamitamab Ravtansine&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Tusamitamab Ravtansine&apos; SubClassOf &apos;CEA-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Tusamitamab Ravtansine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201549</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C117231</classIRI>
<classLabel>Allogeneic Natural Killer Cell Line NK-92</classLabel>
<deletedAxiom>&apos;Allogeneic Natural Killer Cell Line NK-92&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic Natural Killer Cell Line NK-92&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181304</classIRI>
<classLabel>Cytotoxic T-Lymphocytes to Total T-Lymphocytes Ratio Measurement</classLabel>
<deletedAxiom>&apos;Cytotoxic T-Lymphocytes to Total T-Lymphocytes Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Cytotoxic T-Lymphocytes to Total T-Lymphocytes Ratio Measurement&apos; SubClassOf &apos;Cytotoxic T-Lymphocytes to Lymphocytes Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90564</classIRI>
<classLabel>Capmatinib</classLabel>
<deletedAxiom>&apos;Capmatinib&apos; SubClassOf &apos;Angiogenesis Inhibitor&apos;</deletedAxiom>
<deletedAxiom>&apos;Capmatinib&apos; SubClassOf &apos;Tyrosine Kinase Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Capmatinib&apos; SubClassOf &apos;c-Met Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181309</classIRI>
<classLabel>B-Lymphocytes to Leukocytes Ratio Measurement</classLabel>
<deletedAxiom>&apos;B-Lymphocytes to Leukocytes Ratio Measurement&apos; SubClassOf &apos;Lymphocyte to Leukocyte Ratio&apos;</deletedAxiom>
<newAxiom>&apos;B-Lymphocytes to Leukocytes Ratio Measurement&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181265</classIRI>
<classLabel>B-Lymphocytes Subpopulation to Total B-Lymphocytes Ratio Measurement</classLabel>
<deletedAxiom>&apos;B-Lymphocytes Subpopulation to Total B-Lymphocytes Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;B-Lymphocytes Subpopulation to Total B-Lymphocytes Ratio Measurement&apos; SubClassOf &apos;B-Lymphocyte Subpopulation to Lymphocyte Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122924</classIRI>
<classLabel>Anti-B7-H3 Antibody DS-5573a</classLabel>
<newAxiom>&apos;Anti-B7-H3 Antibody DS-5573a&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122921</classIRI>
<classLabel>Rosmantuzumab</classLabel>
<newAxiom>&apos;Rosmantuzumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156400</classIRI>
<classLabel>Anetumab</classLabel>
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<newAxiom>&apos;Anetumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
<newAxiom>&apos;Anetumab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201534</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Emirodatamab</classLabel>
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<newAxiom>&apos;Emirodatamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156141</classIRI>
<classLabel>Mecbotamab Vedotin</classLabel>
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<newAxiom>&apos;Mecbotamab Vedotin&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181024</classIRI>
<classLabel>Anti-CD7 CAR T Cells SenL-T7</classLabel>
<deletedAxiom>&apos;Anti-CD7 CAR T Cells SenL-T7&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD7 CAR T Cells SenL-T7&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD7 CAR T Cells SenL-T7&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201177</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99238</classIRI>
<classLabel>EWSR1/PATZ1 Fusion Gene</classLabel>
<deletedAxiom>&apos;EWSR1/PATZ1 Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<newAxiom>&apos;EWSR1/PATZ1 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99222</classIRI>
<classLabel>Anti-EGFRvIII Antibody Drug Conjugate AMG 595</classLabel>
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<newAxiom>&apos;Anti-EGFRvIII Antibody Drug Conjugate AMG 595&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201551</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99213</classIRI>
<classLabel>EWSR1/WT1 Fusion Gene</classLabel>
<deletedAxiom>&apos;EWSR1/WT1 Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<newAxiom>&apos;EWSR1/WT1 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99200</classIRI>
<classLabel>EWSR1/DDIT3 Fusion Gene</classLabel>
<deletedAxiom>&apos;EWSR1/DDIT3 Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<newAxiom>&apos;EWSR1/DDIT3 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
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<changedClass>
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<classLabel>Anti-GARP Monoclonal Antibody DS-1055a</classLabel>
<deletedAxiom>&apos;Anti-GARP Monoclonal Antibody DS-1055a&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-GARP Monoclonal Antibody DS-1055a&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201536</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99279</classIRI>
<classLabel>FUS/DDIT3 Fusion Gene</classLabel>
<deletedAxiom>&apos;FUS/DDIT3 Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<newAxiom>&apos;FUS/DDIT3 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
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<changedClass>
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<newAxiom>&apos;Autologous Anti-CD22 CAR-4-1BB-TCRz-transduced T-lymphocytes CART22-65s&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201173</newAxiom>
</changedClass>
<changedClass>
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<classLabel>EWSR1/POU5F1 Fusion Gene</classLabel>
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<newAxiom>&apos;EWSR1/POU5F1 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
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<classLabel>EWSR1/NR4A3 Fusion Gene</classLabel>
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<newAxiom>&apos;EWSR1/NR4A3 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
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<changedClass>
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<classLabel>FUS/CREB3L2 Fusion Gene</classLabel>
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<newAxiom>&apos;FUS/CREB3L2 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
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<changedClass>
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<newAxiom>&apos;Autologous Anti-CD38 A2 CAR2-expressing T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201510</newAxiom>
</changedClass>
<changedClass>
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<deletedAxiom>&apos;Anti-BCMA/CD3 Bispecific Monoclonal Antibody&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-BCMA/CD3 Bispecific Monoclonal Antibody&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181104</classIRI>
<classLabel>Bispecific Antibody JNJ-70218902</classLabel>
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<newAxiom>&apos;Bispecific Antibody JNJ-70218902&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26441</classIRI>
<classLabel>Iratumumab</classLabel>
<deletedAxiom>&apos;Iratumumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Iratumumab&apos; SubClassOf &apos;Anti-CD30 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>EWSR1/SP3 Fusion Gene</classLabel>
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<newAxiom>&apos;EWSR1/SP3 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
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<newAxiom>&apos;TAF15/NR4A3 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
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<deletedAxiom>&apos;Anti-PSMA Monoclonal Antibody MLN591-DM1 Immunoconjugate MLN2704&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PSMA Monoclonal Antibody MLN591-DM1 Immunoconjugate MLN2704&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201544</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Non-BRCA Gene Mutation</classLabel>
<deletedAxiom>&apos;Non-BRCA Gene Mutation&apos; SubClassOf &apos;BRAF Gene Alteration Positive&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122406</classIRI>
<classLabel>Duvortuxizumab</classLabel>
<deletedAxiom>&apos;Duvortuxizumab&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Duvortuxizumab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122107</classIRI>
<classLabel>CD45RA to Lymphocyte Ratio Measurement</classLabel>
<deletedAxiom>&apos;CD45RA to Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Blood Cell Count Ratio Measurement&apos;</deletedAxiom>
<newAxiom>&apos;CD45RA to Lymphocyte Ratio Measurement&apos; SubClassOf &apos;CD45 to Lymphocyte Ratio Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1569</classIRI>
<classLabel>Daclizumab</classLabel>
<deletedAxiom>&apos;Daclizumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Daclizumab&apos; SubClassOf &apos;Anti-CD25 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99898</classIRI>
<classLabel>CNDO-109-activated Allogeneic Natural Killer Cells</classLabel>
<deletedAxiom>&apos;CNDO-109-activated Allogeneic Natural Killer Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;CNDO-109-activated Allogeneic Natural Killer Cells&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</newAxiom>
<newAxiom>&apos;CNDO-109-activated Allogeneic Natural Killer Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1554</classIRI>
<classLabel>Edrecolomab</classLabel>
<deletedAxiom>&apos;Edrecolomab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Edrecolomab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201523</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99865</classIRI>
<classLabel>UQCRH/EWSR1 Fusion Gene</classLabel>
<deletedAxiom>&apos;UQCRH/EWSR1 Fusion Gene&apos; SubClassOf &apos;Fusion Gene&apos;</deletedAxiom>
<newAxiom>&apos;UQCRH/EWSR1 Fusion Gene&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C161832</classIRI>
<classLabel>Autologous Anti-CD7 CAR/28zeta CRISPR-edited T-lymphocytes</classLabel>
<newAxiom>&apos;Autologous Anti-CD7 CAR/28zeta CRISPR-edited T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201177</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1321</classIRI>
<classLabel>Muromonab-CD3</classLabel>
<deletedAxiom>&apos;Muromonab-CD3&apos; EquivalentTo &apos;Monoclonal Antibody&apos; and &apos;Immunosuppressant&apos; and (&apos;Chemical_Or_Drug_Has_Mechanism_Of_Action&apos; some &apos;Negative Regulation of Receptor Activation&apos;) and (&apos;Chemical_Or_Drug_Has_Physiologic_Effect&apos; some &apos;Enzyme Inhibition&apos;) and (&apos;Chemical_Or_Drug_Has_Physiologic_Effect&apos; some &apos;Immunosuppressive Effect&apos;) and (&apos;Chemical_Or_Drug_Affects_Gene_Product&apos; some &apos;CD3 Complex&apos;)</deletedAxiom>
<newAxiom>&apos;Muromonab-CD3&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C85466</classIRI>
<classLabel>Natural Killer Cells ZRx101</classLabel>
<deletedAxiom>&apos;Natural Killer Cells ZRx101&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Natural Killer Cells ZRx101&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C85446</classIRI>
<classLabel>Iodine I 131-Labeled Anti-CEA/Anti-HSG Bispecific Monoclonal Antibody TF2</classLabel>
<deletedAxiom>&apos;Iodine I 131-Labeled Anti-CEA/Anti-HSG Bispecific Monoclonal Antibody TF2&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C161507</classIRI>
<classLabel>Focal Cutaneous Irradiation</classLabel>
<deletedAxiom>&apos;Focal Cutaneous Irradiation&apos; SubClassOf &apos;Radiation Therapy&apos;</deletedAxiom>
<newAxiom>&apos;Focal Cutaneous Irradiation&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201542</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1959</classIRI>
<classLabel>Monoclonal Antibody m170</classLabel>
<deletedAxiom>&apos;Monoclonal Antibody m170&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Monoclonal Antibody m170&apos; SubClassOf &apos;Anti-MUC-1 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137682</classIRI>
<classLabel>Budigalimab</classLabel>
<deletedAxiom>&apos;Budigalimab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Budigalimab&apos; SubClassOf &apos;Anti-PD1 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162620</classIRI>
<classLabel>Autologous Anti-CD19/CD22 CAR T-cells AUTO3</classLabel>
<newAxiom>&apos;Autologous Anti-CD19/CD22 CAR T-cells AUTO3&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201173</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162693</classIRI>
<classLabel>Anti-CD39 Monoclonal Antibody TTX-030</classLabel>
<deletedAxiom>&apos;Anti-CD39 Monoclonal Antibody TTX-030&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD39 Monoclonal Antibody TTX-030&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201164</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162699</classIRI>
<classLabel>Anti-CD70 CAR-expressing T Lymphocytes</classLabel>
<deletedAxiom>&apos;Anti-CD70 CAR-expressing T Lymphocytes&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD70 CAR-expressing T Lymphocytes&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD70 CAR-expressing T Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201176</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1716</classIRI>
<classLabel>Lintuzumab</classLabel>
<deletedAxiom>&apos;Lintuzumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Lintuzumab&apos; SubClassOf &apos;Anti-CD33 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162347</classIRI>
<classLabel>Detumomab</classLabel>
<newAxiom>&apos;Detumomab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176988</classIRI>
<classLabel>Anti-CD73 Monoclonal Antibody</classLabel>
<newAxiom>&apos;Anti-CD73 Monoclonal Antibody&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201133</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103827</classIRI>
<classLabel>Pasotuxizumab</classLabel>
<deletedAxiom>&apos;Pasotuxizumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Pasotuxizumab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
<newAxiom>&apos;Pasotuxizumab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201543</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176772</classIRI>
<classLabel>Autologous Anti-CD20 CAR T-cells C-CAR066</classLabel>
<newAxiom>&apos;Autologous Anti-CD20 CAR T-cells C-CAR066&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176740</classIRI>
<classLabel>Interferon Gamma-primed Human Bone Marrow-derived Mesenchymal Stromal Cells</classLabel>
<deletedAxiom>&apos;Interferon Gamma-primed Human Bone Marrow-derived Mesenchymal Stromal Cells&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Interferon Gamma-primed Human Bone Marrow-derived Mesenchymal Stromal Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201556</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C71527</classIRI>
<classLabel>Robatumumab</classLabel>
<deletedAxiom>&apos;Robatumumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Robatumumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Robatumumab&apos; SubClassOf &apos;Anti-IGF1R Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C71531</classIRI>
<classLabel>Ganitumab</classLabel>
<deletedAxiom>&apos;Ganitumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Ganitumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Ganitumab&apos; SubClassOf &apos;Anti-IGF1R Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162296</classIRI>
<classLabel>Anti-CD33/CD3 Bispecific Antibody JNJ-67571244</classLabel>
<deletedAxiom>&apos;Anti-CD33/CD3 Bispecific Antibody JNJ-67571244&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD33/CD3 Bispecific Antibody JNJ-67571244&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD33/CD3 Bispecific Antibody JNJ-67571244&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176568</classIRI>
<classLabel>Autologous Anti-CD22 CAR-expressing T-cells SCRI-CAR22v2</classLabel>
<newAxiom>&apos;Autologous Anti-CD22 CAR-expressing T-cells SCRI-CAR22v2&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201173</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176623</classIRI>
<classLabel>iPSC-derived CD16/IL-15RF-expressing CD38-eliminated NK Cells FT538</classLabel>
<deletedAxiom>&apos;iPSC-derived CD16/IL-15RF-expressing CD38-eliminated NK Cells FT538&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;iPSC-derived CD16/IL-15RF-expressing CD38-eliminated NK Cells FT538&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C117729</classIRI>
<classLabel>Idecabtagene Vicleucel</classLabel>
<deletedAxiom>&apos;Idecabtagene Vicleucel&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Idecabtagene Vicleucel&apos; SubClassOf &apos;Autologous CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C117732</classIRI>
<classLabel>Anti-CD70 Antibody-drug Conjugate SGN-CD70A</classLabel>
<deletedAxiom>&apos;Anti-CD70 Antibody-drug Conjugate SGN-CD70A&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD70 Antibody-drug Conjugate SGN-CD70A&apos; SubClassOf &apos;CD70-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD70 Antibody-drug Conjugate SGN-CD70A&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201550</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142889</classIRI>
<classLabel>Anti-HER2/Anti-CD3 Bispecific Monoclonal Antibody GBR 1302</classLabel>
<deletedAxiom>&apos;Anti-HER2/Anti-CD3 Bispecific Monoclonal Antibody GBR 1302&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-HER2/Anti-CD3 Bispecific Monoclonal Antibody GBR 1302&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-HER2/Anti-CD3 Bispecific Monoclonal Antibody GBR 1302&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142834</classIRI>
<classLabel>Autologous CD19/CD22 Chimeric Antigen Receptor T-cells CT120</classLabel>
<newAxiom>&apos;Autologous CD19/CD22 Chimeric Antigen Receptor T-cells CT120&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201173</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142822</classIRI>
<classLabel>Zigakibart</classLabel>
<newAxiom>&apos;Zigakibart&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91078</classIRI>
<classLabel>Ublituximab</classLabel>
<deletedAxiom>&apos;Ublituximab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Ublituximab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
<newAxiom>&apos;Ublituximab&apos; SubClassOf &apos;Anti-CD20 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91093</classIRI>
<classLabel>Anti-CD123 Monoclonal Antibody CSL360</classLabel>
<deletedAxiom>&apos;Anti-CD123 Monoclonal Antibody CSL360&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD123 Monoclonal Antibody CSL360&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201511</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176018</classIRI>
<classLabel>Anti-CD19-targeting CAR-T Cells</classLabel>
<newAxiom>&apos;Anti-CD19-targeting CAR-T Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176023</classIRI>
<classLabel>Anti-BCMA-targeting CAR-T Cells</classLabel>
<newAxiom>&apos;Anti-BCMA-targeting CAR-T Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176029</classIRI>
<classLabel>Nelistotug</classLabel>
<newAxiom>&apos;Nelistotug&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176027</classIRI>
<classLabel>Allogeneic NKG2D-OX40-CD3zeta-CAR-mbIL-15-expressing Natural Killer Cells NKX101</classLabel>
<deletedAxiom>&apos;Allogeneic NKG2D-OX40-CD3zeta-CAR-mbIL-15-expressing Natural Killer Cells NKX101&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic NKG2D-OX40-CD3zeta-CAR-mbIL-15-expressing Natural Killer Cells NKX101&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</newAxiom>
<newAxiom>&apos;Allogeneic NKG2D-OX40-CD3zeta-CAR-mbIL-15-expressing Natural Killer Cells NKX101&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181943</classIRI>
<classLabel>Autologous Anti-CD19/CD20 CAR-T Cells KITE-363</classLabel>
<newAxiom>&apos;Autologous Anti-CD19/CD20 CAR-T Cells KITE-363&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142374</classIRI>
<classLabel>Adenosine A2A Receptor Antagonist NIR178</classLabel>
<deletedAxiom>&apos;Adenosine A2A Receptor Antagonist NIR178&apos; SubClassOf &apos;Immunostimulant&apos;</deletedAxiom>
<newAxiom>&apos;Adenosine A2A Receptor Antagonist NIR178&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201170</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66250</classIRI>
<classLabel>Ocrelizumab</classLabel>
<deletedAxiom>&apos;Ocrelizumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Ocrelizumab&apos; SubClassOf &apos;Anti-CD20 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156933</classIRI>
<classLabel>Human Anti-CD30 CAR-expressing Autologous T-lymphocytes</classLabel>
<newAxiom>&apos;Human Anti-CD30 CAR-expressing Autologous T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201513</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C117354</classIRI>
<classLabel>Coccidioides immitis</classLabel>
<deletedAxiom>&apos;Coccidioides immitis&apos; SubClassOf &apos;Ascomycota&apos;</deletedAxiom>
<newAxiom>&apos;Coccidioides immitis&apos; SubClassOf &apos;Coccidioides&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201113</classIRI>
<classLabel>Exosome Complex Component RRP40</classLabel>
<deletedAxiom>&apos;Exosome Complex Component RRP40&apos; EquivalentTo &apos;Regulatory Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;RNA Degradation Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Exosome&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cytosol&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;KH Domain&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;RNA Processing&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;EXOSC3 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Exosome Complex Component RRP40&apos; EquivalentTo &apos;RNA Binding Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;RNA Degradation Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Exosome&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cytosol&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;KH Domain&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;RNA Processing&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;EXOSC3 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201111</classIRI>
<classLabel>EXOSC3 Gene</classLabel>
<deletedAxiom>&apos;EXOSC3 Gene&apos; SubClassOf &apos;Regulatory Gene&apos;</deletedAxiom>
<newAxiom>&apos;EXOSC3 Gene&apos; SubClassOf &apos;Ligand Binding Protein Gene&apos;</newAxiom>
<newAxiom>&apos;EXOSC3 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;RNA Binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180402</classIRI>
<classLabel>MAT2A Inhibitor IDE397</classLabel>
<deletedAxiom>&apos;MAT2A Inhibitor IDE397&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;MAT2A Inhibitor IDE397&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201154</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180381</classIRI>
<classLabel>Anti-Senl-h19 CAR T Cells</classLabel>
<deletedAxiom>&apos;Anti-Senl-h19 CAR T Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-Senl-h19 CAR T Cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anti-Senl-h19 CAR T Cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180517</classIRI>
<classLabel>Autologous Anti-gp100:154-162 TCR Tumor Infiltrating Lymphocytes</classLabel>
<deletedAxiom>&apos;Autologous Anti-gp100:154-162 TCR Tumor Infiltrating Lymphocytes&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Anti-gp100:154-162 TCR Tumor Infiltrating Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180598</classIRI>
<classLabel>Autologous Anti-HER2 CAR-T Cells</classLabel>
<newAxiom>&apos;Autologous Anti-HER2 CAR-T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201497</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180595</classIRI>
<classLabel>EGFR/CD3-targeting T-cell Engaging Molecule TAK-186</classLabel>
<deletedAxiom>&apos;EGFR/CD3-targeting T-cell Engaging Molecule TAK-186&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;EGFR/CD3-targeting T-cell Engaging Molecule TAK-186&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180585</classIRI>
<classLabel>Anti-EGFR Antibody-drug Conjugate MRG003</classLabel>
<deletedAxiom>&apos;Anti-EGFR Antibody-drug Conjugate MRG003&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-EGFR Antibody-drug Conjugate MRG003&apos; SubClassOf &apos;EGFR-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-EGFR Antibody-drug Conjugate MRG003&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201551</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180570</classIRI>
<classLabel>Short Hairpin RNA-IL-6 Gene Silencing Anti-CD19 CAR T Cells</classLabel>
<deletedAxiom>&apos;Short Hairpin RNA-IL-6 Gene Silencing Anti-CD19 CAR T Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180524</classIRI>
<classLabel>Tremtelectogene Empogeditemcel</classLabel>
<deletedAxiom>&apos;Tremtelectogene Empogeditemcel&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Tremtelectogene Empogeditemcel&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180529</classIRI>
<classLabel>Autologous Anti-MART-1 F5 TCR Tumor Infiltrating Lymphocytes</classLabel>
<deletedAxiom>&apos;Autologous Anti-MART-1 F5 TCR Tumor Infiltrating Lymphocytes&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Anti-MART-1 F5 TCR Tumor Infiltrating Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C155294</classIRI>
<classLabel>Autologous CD30CAR-CD28-CD3zeta-expressing T-Lymphocytes</classLabel>
<newAxiom>&apos;Autologous CD30CAR-CD28-CD3zeta-expressing T-Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201513</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C155293</classIRI>
<classLabel>Autologous CCR4-CD30CAR-CD28-CD3zeta-expressing T-Lymphocytes</classLabel>
<newAxiom>&apos;Autologous CCR4-CD30CAR-CD28-CD3zeta-expressing T-Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201513</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91701</classIRI>
<classLabel>Zanolimumab</classLabel>
<deletedAxiom>&apos;Zanolimumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Zanolimumab&apos; SubClassOf &apos;Anti-CD4 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66735</classIRI>
<classLabel>CDISC SDTM Trial Blinding Schema Terminology</classLabel>
<newAxiom>&apos;CDISC SDTM Trial Blinding Schema Terminology&apos; SubClassOf &apos;CDISC DDF Terminology&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66732</classIRI>
<classLabel>CDISC SDTM Sex of Study Group Terminology</classLabel>
<newAxiom>&apos;CDISC SDTM Sex of Study Group Terminology&apos; SubClassOf &apos;CDISC DDF Terminology&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91735</classIRI>
<classLabel>Simtuzumab</classLabel>
<newAxiom>&apos;Simtuzumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91733</classIRI>
<classLabel>Margetuximab</classLabel>
<deletedAxiom>&apos;Margetuximab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Margetuximab&apos; SubClassOf &apos;Anti-HER2 Monoclonal Antibody&apos;</newAxiom>
<newAxiom>&apos;Margetuximab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121979</classIRI>
<classLabel>DT2219 Antibody</classLabel>
<deletedAxiom>&apos;DT2219 Antibody&apos; SubClassOf &apos;Antibody&apos;</deletedAxiom>
<newAxiom>&apos;DT2219 Antibody&apos; SubClassOf &apos;Anti-Drug Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C52187</classIRI>
<classLabel>Figitumumab</classLabel>
<newAxiom>&apos;Figitumumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121782</classIRI>
<classLabel>Anti-mesothelin iCasp9M28z CAR-transduced Autologous T Lymphocytes</classLabel>
<newAxiom>&apos;Anti-mesothelin iCasp9M28z CAR-transduced Autologous T Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201275</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121445</classIRI>
<classLabel>Allogeneic CD3- CD19- Selected Natural Killer Cells</classLabel>
<deletedAxiom>&apos;Allogeneic CD3- CD19- Selected Natural Killer Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic CD3- CD19- Selected Natural Killer Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121231</classIRI>
<classLabel>Anti-CD122 Humanized Monoclonal Antibody Mik-Beta-1</classLabel>
<newAxiom>&apos;Anti-CD122 Humanized Monoclonal Antibody Mik-Beta-1&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160891</classIRI>
<classLabel>Adipose-derived Expanded Mesenchymal Stem Cells SCM-010</classLabel>
<deletedAxiom>&apos;Adipose-derived Expanded Mesenchymal Stem Cells SCM-010&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Adipose-derived Expanded Mesenchymal Stem Cells SCM-010&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201556</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160621</classIRI>
<classLabel>Allogeneic CD34+-enriched and CD45RA-depleted PBSCs</classLabel>
<newAxiom>&apos;Allogeneic CD34+-enriched and CD45RA-depleted PBSCs&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201557</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160626</classIRI>
<classLabel>Allogeneic CD34-positive Enriched Peripheral Blood Stem Cells</classLabel>
<newAxiom>&apos;Allogeneic CD34-positive Enriched Peripheral Blood Stem Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201557</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C135632</classIRI>
<classLabel>Vixtimotamab</classLabel>
<deletedAxiom>&apos;Vixtimotamab&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Vixtimotamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C135634</classIRI>
<classLabel>Autologous Tumor Infiltrating Lymphocytes LN-145</classLabel>
<deletedAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes LN-145&apos; SubClassOf &apos;Therapeutic Tumor Infiltrating Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes LN-145&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
<newAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes LN-145&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C169042</classIRI>
<classLabel>Exagamglogene Autotemcel</classLabel>
<deletedAxiom>&apos;Exagamglogene Autotemcel&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Exagamglogene Autotemcel&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C169053</classIRI>
<classLabel>Anti-PSMA/CD3 Bispecific Antibody CCW702</classLabel>
<deletedAxiom>&apos;Anti-PSMA/CD3 Bispecific Antibody CCW702&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA/CD3 Bispecific Antibody CCW702&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-PSMA/CD3 Bispecific Antibody CCW702&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PSMA/CD3 Bispecific Antibody CCW702&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
<newAxiom>&apos;Anti-PSMA/CD3 Bispecific Antibody CCW702&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201543</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C169051</classIRI>
<classLabel>Autologous Anti-B7-H3 CAR Retroviral Vector-transduced T Cells</classLabel>
<newAxiom>&apos;Autologous Anti-B7-H3 CAR Retroviral Vector-transduced T Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201492</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C169064</classIRI>
<classLabel>TEK Gene Mutation</classLabel>
<newAxiom>&apos;TEK Gene Mutation&apos; SubClassOf &apos;Receptor Tyrosine Kinase Gene Mutation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160348</classIRI>
<classLabel>Anti-CD123/CD3 BiTE Antibody SAR440234</classLabel>
<deletedAxiom>&apos;Anti-CD123/CD3 BiTE Antibody SAR440234&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD123/CD3 BiTE Antibody SAR440234&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201511</newAxiom>
<newAxiom>&apos;Anti-CD123/CD3 BiTE Antibody SAR440234&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
<newAxiom>&apos;Anti-CD123/CD3 BiTE Antibody SAR440234&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174931</classIRI>
<classLabel>Tebrocabtagene Autoleucel</classLabel>
<deletedAxiom>&apos;Tebrocabtagene Autoleucel&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<deletedAxiom>&apos;Tebrocabtagene Autoleucel&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<deletedAxiom>&apos;Tebrocabtagene Autoleucel&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Tebrocabtagene Autoleucel&apos; SubClassOf &apos;Autologous CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13723</classIRI>
<classLabel>Repair Complex</classLabel>
<newAxiom>&apos;Repair Complex&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Repair&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174763</classIRI>
<classLabel>Gemibotulinumtoxin A</classLabel>
<deletedAxiom>&apos;Gemibotulinumtoxin A&apos; SubClassOf &apos;Bacterial Toxin&apos;</deletedAxiom>
<newAxiom>&apos;Gemibotulinumtoxin A&apos; SubClassOf &apos;Botulinum Toxin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175823</classIRI>
<classLabel>Mipasetamab Uzoptirine</classLabel>
<deletedAxiom>&apos;Mipasetamab Uzoptirine&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Mipasetamab Uzoptirine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175858</classIRI>
<classLabel>Tarlatamab</classLabel>
<deletedAxiom>&apos;Tarlatamab&apos; SubClassOf &apos;Bispecific Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Tarlatamab&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Tarlatamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175943</classIRI>
<classLabel>Welgenaleucel</classLabel>
<newAxiom>&apos;Welgenaleucel&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175980</classIRI>
<classLabel>Allogeneic Anti-CD30 CAR-Epstein-Barr Virus-specific T-lymphocytes</classLabel>
<deletedAxiom>&apos;Allogeneic Anti-CD30 CAR-Epstein-Barr Virus-specific T-lymphocytes&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Allogeneic Anti-CD30 CAR-Epstein-Barr Virus-specific T-lymphocytes&apos; SubClassOf &apos;Therapeutic Allogeneic Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic Anti-CD30 CAR-Epstein-Barr Virus-specific T-lymphocytes&apos; SubClassOf &apos;Allogeneic CAR-T Cells&apos;</newAxiom>
<newAxiom>&apos;Allogeneic Anti-CD30 CAR-Epstein-Barr Virus-specific T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201513</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175977</classIRI>
<classLabel>Anti-CD20/Anti-CD22 CAR T-cells</classLabel>
<deletedAxiom>&apos;Anti-CD20/Anti-CD22 CAR T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD20/Anti-CD22 CAR T-cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD20/Anti-CD22 CAR T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201173</newAxiom>
<newAxiom>&apos;Anti-CD20/Anti-CD22 CAR T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102758</classIRI>
<classLabel>Tisagenlecleucel</classLabel>
<newAxiom>&apos;Tisagenlecleucel&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102784</classIRI>
<classLabel>Talacotuzumab</classLabel>
<deletedAxiom>&apos;Talacotuzumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Talacotuzumab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201511</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175778</classIRI>
<classLabel>Emerfetamab</classLabel>
<deletedAxiom>&apos;Emerfetamab&apos; SubClassOf &apos;Bispecific Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Emerfetamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175750</classIRI>
<classLabel>Prabotulinumtoxin A</classLabel>
<deletedAxiom>&apos;Prabotulinumtoxin A&apos; SubClassOf &apos;Bacterial Toxin&apos;</deletedAxiom>
<newAxiom>&apos;Prabotulinumtoxin A&apos; SubClassOf &apos;Botulinum Toxin&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Acapatamab</classLabel>
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<newAxiom>&apos;DNA Repair Protein RAD51 Homolog 4&apos; EquivalentTo &apos;DNA Repair Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Homologous Recombination Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Centrosome&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201206) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;DNA Binding Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Binding&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Recombination Repair&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Mitotic Recombination&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Telomere Maintenance&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Meiotic Recombination&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RAD51 Gene&apos;)</newAxiom>
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<newAxiom>&apos;Autologous CRISPR-Cas9 Modified/BCL11A Gene-disrupted Human Hematopoietic Stem and Progenitor Cells OTQ923&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
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<deletedAxiom>&apos;Anti-CD22-CAR m971-BBz Lentiviral Vector-transduced Autologous T Lymphocytes CRG-022&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD22-CAR m971-BBz Lentiviral Vector-transduced Autologous T Lymphocytes CRG-022&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201173</newAxiom>
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<newAxiom>&apos;Cytochrome P450 4V2&apos; EquivalentTo &apos;Cytochrome P450&apos; and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Endoplasmic Reticulum&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Oxidation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Visual Perception&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Fatty Acid Metabolism&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CYP4V2 Gene&apos;)</newAxiom>
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<newAxiom>&apos;Gamma-Delta T-Lymphocyte Subpopulation to Gamma-Delta T-Lymphocyte Ratio Measurement&apos; SubClassOf &apos;Gamma-Delta T-Lymphocyte to T-Lymphocyte Ratio Measurement&apos;</newAxiom>
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<deletedAxiom>&apos;Anti-EGFRvIII/CD3 Bispecific Antibody hEGFRvIII:CD3 bi-scFv&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-EGFRvIII/CD3 Bispecific Antibody hEGFRvIII:CD3 bi-scFv&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
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<newAxiom>&apos;Autologous Tumor Infiltrating Lymphocytes GT201&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116329</classIRI>
<classLabel>Autologous CD123CAR-CD28-CD3zeta-EGFRt-expressing T Lymphocytes</classLabel>
<newAxiom>&apos;Autologous CD123CAR-CD28-CD3zeta-EGFRt-expressing T Lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201493</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C155909</classIRI>
<classLabel>Autologous Anti-mesothelin CAR-CD3zeta-4-1-BB-expressing T-cells</classLabel>
<newAxiom>&apos;Autologous Anti-mesothelin CAR-CD3zeta-4-1-BB-expressing T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201275</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180638</classIRI>
<classLabel>Atidarsagene Autotemcel</classLabel>
<deletedAxiom>&apos;Atidarsagene Autotemcel&apos; SubClassOf &apos;Adoptive Cell Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Atidarsagene Autotemcel&apos; SubClassOf &apos;Gene Therapy Agent&apos;</newAxiom>
<newAxiom>&apos;Atidarsagene Autotemcel&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189056</classIRI>
<classLabel>Anti-HLA-A2-MAGE-A4/Anti-CD3 Bispecific Antibody RO7444973</classLabel>
<deletedAxiom>&apos;Anti-HLA-A2-MAGE-A4/Anti-CD3 Bispecific Antibody RO7444973&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-HLA-A2-MAGE-A4/Anti-CD3 Bispecific Antibody RO7444973&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-HLA-A2-MAGE-A4/Anti-CD3 Bispecific Antibody RO7444973&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189049</classIRI>
<classLabel>Anti-CD38-CAR-TCRz/4-1BB-expressing T-lymphocytes</classLabel>
<deletedAxiom>&apos;Anti-CD38-CAR-TCRz/4-1BB-expressing T-lymphocytes&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD38-CAR-TCRz/4-1BB-expressing T-lymphocytes&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD38-CAR-TCRz/4-1BB-expressing T-lymphocytes&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201510</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180675</classIRI>
<classLabel>Anti-PD-L1/Claudin18.2 Bispecific Antibody Q-1802</classLabel>
<newAxiom>&apos;Anti-PD-L1/Claudin18.2 Bispecific Antibody Q-1802&apos; SubClassOf &apos;Anti-PD-L1 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189093</classIRI>
<classLabel>Membrane-bound IL-15-expressing Tumor-infiltrating Lymphocytes OBX-115</classLabel>
<deletedAxiom>&apos;Membrane-bound IL-15-expressing Tumor-infiltrating Lymphocytes OBX-115&apos; SubClassOf &apos;Therapeutic Tumor Infiltrating Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Membrane-bound IL-15-expressing Tumor-infiltrating Lymphocytes OBX-115&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189059</classIRI>
<classLabel>Anti-CD19/Anti-CD79b 4SCAR-expressing Bispecific T-cells</classLabel>
<deletedAxiom>&apos;Anti-CD19/Anti-CD79b 4SCAR-expressing Bispecific T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD19/Anti-CD79b 4SCAR-expressing Bispecific T-cells&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD19/Anti-CD79b 4SCAR-expressing Bispecific T-cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189058</classIRI>
<classLabel>Anti-CD19/Anti-CD70 4SCAR-expressing Bispecific T-cells</classLabel>
<deletedAxiom>&apos;Anti-CD19/Anti-CD70 4SCAR-expressing Bispecific T-cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD19/Anti-CD70 4SCAR-expressing Bispecific T-cells&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD19/Anti-CD70 4SCAR-expressing Bispecific T-cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201176</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201541</classIRI>
<classLabel>Whole-Ventricular Radiation Therapy</classLabel>
<newAxiom>'Whole-Ventricular Radiation Therapy' SubClassOf 'Brain Irradiation'</newAxiom>
<newAxiom>'Whole-Ventricular Radiation Therapy' SubClassOf 'External Beam Radiation Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201540</classIRI>
<classLabel>Cardiomyocyte-Specific Unmethylated CpG Pattern Positive</classLabel>
<newAxiom>'Cardiomyocyte-Specific Unmethylated CpG Pattern Positive' SubClassOf 'Genetic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201534</classIRI>
<classLabel>Anti-mesothelin Monoclonal Antibody</classLabel>
<newAxiom>'Anti-mesothelin Monoclonal Antibody' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201533</classIRI>
<classLabel>Ganglioside GD2 Negative</classLabel>
<newAxiom>'Ganglioside GD2 Negative' SubClassOf 'Expression Positive'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201532</classIRI>
<classLabel>Cyclophosphamide/Rituximab Regimen</classLabel>
<newAxiom>'Cyclophosphamide/Rituximab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Cyclophosphamide'</newAxiom>
<newAxiom>'Cyclophosphamide/Rituximab Regimen' SubClassOf 'Regimen Used to Treat Castleman disease'</newAxiom>
<newAxiom>'Cyclophosphamide/Rituximab Regimen' SubClassOf 'Regimen Used to Treat Non-Hodgkin Lymphoma'</newAxiom>
<newAxiom>'Cyclophosphamide/Rituximab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Rituximab'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201531</classIRI>
<classLabel>Cyclophosphamide/Prednisone/Rituximab Regimen</classLabel>
<newAxiom>'Cyclophosphamide/Prednisone/Rituximab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Cyclophosphamide'</newAxiom>
<newAxiom>'Cyclophosphamide/Prednisone/Rituximab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Prednisone'</newAxiom>
<newAxiom>'Cyclophosphamide/Prednisone/Rituximab Regimen' SubClassOf 'Regimen Used to Treat Castleman disease'</newAxiom>
<newAxiom>'Cyclophosphamide/Prednisone/Rituximab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Rituximab'</newAxiom>
<newAxiom>'Cyclophosphamide/Prednisone/Rituximab Regimen' SubClassOf 'Regimen Used to Treat Non-Hodgkin Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201538</classIRI>
<classLabel>RFLNA wt Allele</classLabel>
<newAxiom>'RFLNA wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '12q24.31'</newAxiom>
<newAxiom>'RFLNA wt Allele' SubClassOf 'RFLNA Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201537</classIRI>
<classLabel>RFLNA Gene</classLabel>
<newAxiom>'RFLNA Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein-Protein Interaction'</newAxiom>
<newAxiom>'RFLNA Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Skeletal Development'</newAxiom>
<newAxiom>'RFLNA Gene' SubClassOf 'Ligand Binding Protein Gene'</newAxiom>
<newAxiom>'RFLNA Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cytoskeletal Modeling'</newAxiom>
<newAxiom>'RFLNA Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Negative Regulation of Cell Differentiation'</newAxiom>
<newAxiom>'RFLNA Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Mineralization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201536</classIRI>
<classLabel>Anti-GARP Monoclonal Antibody</classLabel>
<newAxiom>'Anti-GARP Monoclonal Antibody' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201535</classIRI>
<classLabel>Anti-mesothelin Antibody-drug Conjugate</classLabel>
<newAxiom>'Anti-mesothelin Antibody-drug Conjugate' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201539</classIRI>
<classLabel>Refilin-A</classLabel>
<newAxiom>'Refilin-A' EquivalentTo 'Ligand Binding Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Actin Filament') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Proline-Rich Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Mineralization') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Protein Interaction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Skeletal Development') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cytoskeletal Modeling') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Negative Regulation of Cell Differentiation') and ('Gene_Product_Encoded_By_Gene' some 'RFLNA Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201530</classIRI>
<classLabel>Binary Mask</classLabel>
<newAxiom>'Binary Mask' SubClassOf 'Data Mapping'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201523</classIRI>
<classLabel>Anti-EpCAM Monoclonal Antibody</classLabel>
<newAxiom>'Anti-EpCAM Monoclonal Antibody' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201522</classIRI>
<classLabel>Anti-TNFR2 Monoclonal Antibody</classLabel>
<newAxiom>'Anti-TNFR2 Monoclonal Antibody' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201521</classIRI>
<classLabel>Parkinsonism with Polyneuropathy</classLabel>
<newAxiom>'Parkinsonism with Polyneuropathy' SubClassOf 'Parkinson's Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201520</classIRI>
<classLabel>Parkinson Disease 17</classLabel>
<newAxiom>'Parkinson Disease 17' SubClassOf 'Parkinson's Disease'</newAxiom>
<newAxiom>'Parkinson Disease 17' SubClassOf 'Disease_Mapped_To_Gene' some 'VPS35 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201527</classIRI>
<classLabel>CD371-specific/YSNVz/IL-18 CAR T Cells</classLabel>
<newAxiom>'CD371-specific/YSNVz/IL-18 CAR T Cells' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'CD371-specific/YSNVz/IL-18 CAR T Cells' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201526</classIRI>
<classLabel>R-ICE Plus Bortezomib Regimen</classLabel>
<newAxiom>'R-ICE Plus Bortezomib Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Carboplatin'</newAxiom>
<newAxiom>'R-ICE Plus Bortezomib Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Bortezomib'</newAxiom>
<newAxiom>'R-ICE Plus Bortezomib Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Rituximab'</newAxiom>
<newAxiom>'R-ICE Plus Bortezomib Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Ifosfamide'</newAxiom>
<newAxiom>'R-ICE Plus Bortezomib Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Etoposide'</newAxiom>
<newAxiom>'R-ICE Plus Bortezomib Regimen' SubClassOf 'Regimen Used to Treat Non-Hodgkin Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201525</classIRI>
<classLabel>STING Agonist CRD3874</classLabel>
<newAxiom>'STING Agonist CRD3874' SubClassOf 'STING Agonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201524</classIRI>
<classLabel>Anti-CD30/CD3 Bispecific Antibody GEN3017</classLabel>
<newAxiom>'Anti-CD30/CD3 Bispecific Antibody GEN3017' SubClassOf 'Anti-CD30 Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-CD30/CD3 Bispecific Antibody GEN3017' SubClassOf 'T-cell Engaging Bispecific Antibody'</newAxiom>
<newAxiom>'Anti-CD30/CD3 Bispecific Antibody GEN3017' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201529</classIRI>
<classLabel>High-dose Methotrexate/Rituximab Regimen</classLabel>
<newAxiom>'High-dose Methotrexate/Rituximab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Methotrexate'</newAxiom>
<newAxiom>'High-dose Methotrexate/Rituximab Regimen' SubClassOf 'Regimen Used to Treat Central Nervous System Neoplasm'</newAxiom>
<newAxiom>'High-dose Methotrexate/Rituximab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Rituximab'</newAxiom>
<newAxiom>'High-dose Methotrexate/Rituximab Regimen' SubClassOf 'Regimen Used to Treat Non-Hodgkin Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201528</classIRI>
<classLabel>Age in Days at Recurrence</classLabel>
<newAxiom>'Age in Days at Recurrence' SubClassOf 'Age-Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201556</classIRI>
<classLabel>Therapeutic Mesenchymal Stem Cells</classLabel>
<newAxiom>'Therapeutic Mesenchymal Stem Cells' SubClassOf 'Adoptive Cell Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201555</classIRI>
<classLabel>Hematocrit Less than 45 Percent</classLabel>
<newAxiom>'Hematocrit Less than 45 Percent' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201554</classIRI>
<classLabel>Therapeutic Hematopoietic Stem Cells</classLabel>
<newAxiom>'Therapeutic Hematopoietic Stem Cells' SubClassOf 'Adoptive Cell Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201553</classIRI>
<classLabel>RSVPreF3/AS01E RSV Vaccine</classLabel>
<newAxiom>'RSVPreF3/AS01E RSV Vaccine' SubClassOf 'Inactivated Vaccine'</newAxiom>
<newAxiom>'RSVPreF3/AS01E RSV Vaccine' SubClassOf 'Viral Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201557</classIRI>
<classLabel>Therapeutic Peripheral Blood Stem Cells</classLabel>
<newAxiom>'Therapeutic Peripheral Blood Stem Cells' SubClassOf 'Adoptive Cell Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201552</classIRI>
<classLabel>Anti-c-Met Antibody-drug Conjugate</classLabel>
<newAxiom>'Anti-c-Met Antibody-drug Conjugate' SubClassOf 'c-Met-targeting Agent'</newAxiom>
<newAxiom>'Anti-c-Met Antibody-drug Conjugate' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201551</classIRI>
<classLabel>Anti-EGFR Antibody-drug Conjugate</classLabel>
<newAxiom>'Anti-EGFR Antibody-drug Conjugate' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
<newAxiom>'Anti-EGFR Antibody-drug Conjugate' SubClassOf 'EGFR-targeting Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201550</classIRI>
<classLabel>Anti-CD70 Antibody-drug Conjugate</classLabel>
<newAxiom>'Anti-CD70 Antibody-drug Conjugate' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
<newAxiom>'Anti-CD70 Antibody-drug Conjugate' SubClassOf 'CD70-targeting Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201545</classIRI>
<classLabel>Therapeutic Natural Killer Cells Preparation</classLabel>
<newAxiom>'Therapeutic Natural Killer Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201544</classIRI>
<classLabel>Anti-PSMA Antibody-drug Conjugate</classLabel>
<newAxiom>'Anti-PSMA Antibody-drug Conjugate' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
<newAxiom>'Anti-PSMA Antibody-drug Conjugate' SubClassOf 'PSMA-targeting Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201543</classIRI>
<classLabel>Anti-PSMA Monoclonal Antibody</classLabel>
<newAxiom>'Anti-PSMA Monoclonal Antibody' SubClassOf 'Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-PSMA Monoclonal Antibody' SubClassOf 'PSMA-targeting Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201542</classIRI>
<classLabel>Focal Radiation Therapy</classLabel>
<newAxiom>'Focal Radiation Therapy' SubClassOf 'External Beam Radiation Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201549</classIRI>
<classLabel>Anti-CEA Antibody-drug Conjugate</classLabel>
<newAxiom>'Anti-CEA Antibody-drug Conjugate' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
<newAxiom>'Anti-CEA Antibody-drug Conjugate' SubClassOf 'CEA-targeting Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201548</classIRI>
<classLabel>Exhaled Carbon Monoxide Concentration Greater than or Equal to 10 ppm</classLabel>
<newAxiom>'Exhaled Carbon Monoxide Concentration Greater than or Equal to 10 ppm' SubClassOf 'Clinical Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201547</classIRI>
<classLabel>Therapeutic Tumor Infiltrating Lymphocytes Preparation</classLabel>
<newAxiom>'Therapeutic Tumor Infiltrating Lymphocytes Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201546</classIRI>
<classLabel>Momelotinib Dihydrochloride Monohydrate</classLabel>
<newAxiom>'Momelotinib Dihydrochloride Monohydrate' SubClassOf 'ALK Inhibitor'</newAxiom>
<newAxiom>'Momelotinib Dihydrochloride Monohydrate' SubClassOf 'JAK Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201420</classIRI>
<classLabel>Pemphigoid Autoantigens</classLabel>
<newAxiom>'Pemphigoid Autoantigens' SubClassOf 'Basement Membrane Antigens'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201413</classIRI>
<classLabel>Ganglioside GM3</classLabel>
<newAxiom>'Ganglioside GM3' SubClassOf 'Ganglioside'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201412</classIRI>
<classLabel>Ganglioside GT1A</classLabel>
<newAxiom>'Ganglioside GT1A' SubClassOf 'Ganglioside'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201411</classIRI>
<classLabel>Ganglioside GM4</classLabel>
<newAxiom>'Ganglioside GM4' SubClassOf 'Ganglioside'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201410</classIRI>
<classLabel>Gamma Aminobutyrate B Receptor</classLabel>
<newAxiom>'Gamma Aminobutyrate B Receptor' SubClassOf 'Protein or Riboprotein Complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201417</classIRI>
<classLabel>Ganglioside GQ1B</classLabel>
<newAxiom>'Ganglioside GQ1B' SubClassOf 'Ganglioside'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201416</classIRI>
<classLabel>Ganglioside GD1B</classLabel>
<newAxiom>'Ganglioside GD1B' SubClassOf 'Ganglioside'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201415</classIRI>
<classLabel>Ganglioside GD1A</classLabel>
<newAxiom>'Ganglioside GD1A' SubClassOf 'Ganglioside'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201414</classIRI>
<classLabel>Ganglioside GT1B</classLabel>
<newAxiom>'Ganglioside GT1B' SubClassOf 'Ganglioside'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201419</classIRI>
<classLabel>Thyroid Autoantigens</classLabel>
<newAxiom>'Thyroid Autoantigens' SubClassOf 'Autoantigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201418</classIRI>
<classLabel>Acetylcholine Receptors</classLabel>
<newAxiom>'Acetylcholine Receptors' SubClassOf 'Protein or Riboprotein Complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201402</classIRI>
<classLabel>Parietaria officinalis Pollen Antigen</classLabel>
<newAxiom>'Parietaria officinalis Pollen Antigen' SubClassOf 'Allergen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201401</classIRI>
<classLabel>Meadow Fescue Pollen Antigen</classLabel>
<newAxiom>'Meadow Fescue Pollen Antigen' SubClassOf 'Allergen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201400</classIRI>
<classLabel>Ovarian Autoantigens</classLabel>
<newAxiom>'Ovarian Autoantigens' SubClassOf 'Autoantigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201406</classIRI>
<classLabel>Italian Cypress Pollen Antigen</classLabel>
<newAxiom>'Italian Cypress Pollen Antigen' SubClassOf 'Allergen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201405</classIRI>
<classLabel>Stinging Nettle Pollen Antigen</classLabel>
<newAxiom>'Stinging Nettle Pollen Antigen' SubClassOf 'Allergen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201404</classIRI>
<classLabel>Cultivated Oat Pollen Antigen</classLabel>
<newAxiom>'Cultivated Oat Pollen Antigen' SubClassOf 'Allergen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201403</classIRI>
<classLabel>Parietaria judaica Pollen Antigen</classLabel>
<newAxiom>'Parietaria judaica Pollen Antigen' SubClassOf 'Allergen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201409</classIRI>
<classLabel>MI-2 Antigens</classLabel>
<newAxiom>'MI-2 Antigens' SubClassOf 'Autoantigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201408</classIRI>
<classLabel>Oriental Cockroach Antigen</classLabel>
<newAxiom>'Oriental Cockroach Antigen' SubClassOf 'Allergen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201407</classIRI>
<classLabel>Grey Alder Pollen Antigen</classLabel>
<newAxiom>'Grey Alder Pollen Antigen' SubClassOf 'Allergen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201442</classIRI>
<classLabel>Human Bocavirus Antigen Measurement</classLabel>
<newAxiom>'Human Bocavirus Antigen Measurement' SubClassOf 'Microbiology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201441</classIRI>
<classLabel>Chikungunya Virus RNA Measurement</classLabel>
<newAxiom>'Chikungunya Virus RNA Measurement' SubClassOf 'Microbiology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201440</classIRI>
<classLabel>Zika Virus RNA Measurement</classLabel>
<newAxiom>'Zika Virus RNA Measurement' SubClassOf 'Microbiology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201435</classIRI>
<classLabel>Posterior Limb of Internal Capsule</classLabel>
<newAxiom>'Posterior Limb of Internal Capsule' SubClassOf 'Brain Part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201434</classIRI>
<classLabel>Mid Level Right Ventricle</classLabel>
<newAxiom>'Mid Level Right Ventricle' SubClassOf 'Heart Part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201433</classIRI>
<classLabel>Base of the Right Ventricle</classLabel>
<newAxiom>'Base of the Right Ventricle' SubClassOf 'Heart Part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201432</classIRI>
<classLabel>Trigeminal Cave</classLabel>
<newAxiom>'Trigeminal Cave' SubClassOf 'Central Nervous System Part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201439</classIRI>
<classLabel>Gardnerella vaginalis DNA Measurement</classLabel>
<newAxiom>'Gardnerella vaginalis DNA Measurement' SubClassOf 'Gardnerella vaginalis Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201438</classIRI>
<classLabel>Candida albicans DNA Measurement</classLabel>
<newAxiom>'Candida albicans DNA Measurement' SubClassOf 'Candida albicans Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201437</classIRI>
<classLabel>Replication Competent Lentivirus RNA Measurement</classLabel>
<newAxiom>'Replication Competent Lentivirus RNA Measurement' SubClassOf 'Microbiology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201436</classIRI>
<classLabel>Spirochaetales Measurement</classLabel>
<newAxiom>'Spirochaetales Measurement' SubClassOf 'Gram Negative Bacteria Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201431</classIRI>
<classLabel>Duke Pancreatic Monoclonal Antigen Type 2 Measurement</classLabel>
<newAxiom>'Duke Pancreatic Monoclonal Antigen Type 2 Measurement' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201430</classIRI>
<classLabel>Phenylpyruvate Measurement</classLabel>
<newAxiom>'Phenylpyruvate Measurement' SubClassOf 'Phenylketone Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201424</classIRI>
<classLabel>Rheumatoid Factor IgA Autoantibody Measurement</classLabel>
<newAxiom>'Rheumatoid Factor IgA Autoantibody Measurement' SubClassOf 'Rheumatoid Factor Autoantibody Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201423</classIRI>
<classLabel>Thyrotropin Binding Inhibitory Immunoglobulin Autoantibody Measurement</classLabel>
<newAxiom>'Thyrotropin Binding Inhibitory Immunoglobulin Autoantibody Measurement' SubClassOf 'Immunoglobulin Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201422</classIRI>
<classLabel>Thyroid Stimulating Immunoglobulin Autoantibody Measurement</classLabel>
<newAxiom>'Thyroid Stimulating Immunoglobulin Autoantibody Measurement' SubClassOf 'Thyroid Stimulating Immunoglobulin Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201421</classIRI>
<classLabel>Modulating Autoantibody to Autoantibody Ratio Measurement</classLabel>
<newAxiom>'Modulating Autoantibody to Autoantibody Ratio Measurement' SubClassOf 'Autoantibody Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201428</classIRI>
<classLabel>Aspartate Aminotransferase Isoenzyme M Measurement</classLabel>
<newAxiom>'Aspartate Aminotransferase Isoenzyme M Measurement' SubClassOf 'Aspartate Aminotransferase Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201427</classIRI>
<classLabel>Aspartate Aminotransferase Isoenzyme C Measurement</classLabel>
<newAxiom>'Aspartate Aminotransferase Isoenzyme C Measurement' SubClassOf 'Aspartate Aminotransferase Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201426</classIRI>
<classLabel>Rheumatoid Factor IgM Autoantibody Measurement</classLabel>
<newAxiom>'Rheumatoid Factor IgM Autoantibody Measurement' SubClassOf 'Rheumatoid Factor Autoantibody Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201425</classIRI>
<classLabel>Rheumatoid Factor IgG Autoantibody Measurement</classLabel>
<newAxiom>'Rheumatoid Factor IgG Autoantibody Measurement' SubClassOf 'Rheumatoid Factor Autoantibody Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201429</classIRI>
<classLabel>Monocyte Distribution Width Measurement</classLabel>
<newAxiom>'Monocyte Distribution Width Measurement' SubClassOf 'Hematology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201460</classIRI>
<classLabel>N-Acetyl Aspartate to Creatine and Choline Ratio Measurement</classLabel>
<newAxiom>'N-Acetyl Aspartate to Creatine and Choline Ratio Measurement' SubClassOf 'Chemistry Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201464</classIRI>
<classLabel>Metabolic Ratio of Accumulation Ratios</classLabel>
<newAxiom>'Metabolic Ratio of Accumulation Ratios' SubClassOf 'Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201463</classIRI>
<classLabel>Final Subject Contact</classLabel>
<newAxiom>'Final Subject Contact' SubClassOf 'Planned Trial Subject Contact'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201462</classIRI>
<classLabel>Ponte-di-Legno Consortium 2022</classLabel>
<newAxiom>'Ponte-di-Legno Consortium 2022' SubClassOf 'Classification'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201461</classIRI>
<classLabel>Resting Tremor Evaluation</classLabel>
<newAxiom>'Resting Tremor Evaluation' SubClassOf 'Tremor Evaluation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201457</classIRI>
<classLabel>N-Acetyl Aspartate to Choline Ratio Measurement</classLabel>
<newAxiom>'N-Acetyl Aspartate to Choline Ratio Measurement' SubClassOf 'Chemistry Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201456</classIRI>
<classLabel>N-Acetyl Aspartate to Creatine Ratio Measurement</classLabel>
<newAxiom>'N-Acetyl Aspartate to Creatine Ratio Measurement' SubClassOf 'Amino Acid Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201455</classIRI>
<classLabel>Creatine Measurement</classLabel>
<newAxiom>'Creatine Measurement' SubClassOf 'Amino Acid Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201454</classIRI>
<classLabel>Choline Measurement</classLabel>
<newAxiom>'Choline Measurement' SubClassOf 'Chemistry Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201459</classIRI>
<classLabel>Creatine and Choline Measurement</classLabel>
<newAxiom>'Creatine and Choline Measurement' SubClassOf 'Chemistry Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201458</classIRI>
<classLabel>Choline to Creatine Ratio Measurement</classLabel>
<newAxiom>'Choline to Creatine Ratio Measurement' SubClassOf 'Chemistry Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201453</classIRI>
<classLabel>C3 Enriched Glutamate and Glutamine Measurement</classLabel>
<newAxiom>'C3 Enriched Glutamate and Glutamine Measurement' SubClassOf 'Glutamate and Glutamine Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201452</classIRI>
<classLabel>C4 Enriched Glutamine Measurement</classLabel>
<newAxiom>'C4 Enriched Glutamine Measurement' SubClassOf 'Glutamine Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201451</classIRI>
<classLabel>C4 Enriched Glutamate Measurement</classLabel>
<newAxiom>'C4 Enriched Glutamate Measurement' SubClassOf 'Glutamate Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201450</classIRI>
<classLabel>Used Prohibited Medication Indicator</classLabel>
<newAxiom>'Used Prohibited Medication Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201446</classIRI>
<classLabel>B-Cell Lymphoma 2 Measurement</classLabel>
<newAxiom>'B-Cell Lymphoma 2 Measurement' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201445</classIRI>
<classLabel>Influenza A Virus Subtype H3N2</classLabel>
<newAxiom>'Influenza A Virus Subtype H3N2' SubClassOf 'Influenza A Virus Subtype H3'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201444</classIRI>
<classLabel>Spirochaetales</classLabel>
<newAxiom>'Spirochaetales' SubClassOf 'Spirochaetes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201443</classIRI>
<classLabel>HIV Antigen/Antibody Measurement</classLabel>
<newAxiom>'HIV Antigen/Antibody Measurement' SubClassOf 'Human Immunodeficiency Virus Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201449</classIRI>
<classLabel>Number of Involved Lymph Node Levels</classLabel>
<newAxiom>'Number of Involved Lymph Node Levels' SubClassOf 'Number of Disease-Involved Anatomic Sites'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201448</classIRI>
<classLabel>Surgical Margin Distance Measurement</classLabel>
<newAxiom>'Surgical Margin Distance Measurement' SubClassOf 'Cancer Diagnostic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201447</classIRI>
<classLabel>Adequate Surgical Margin Indicator</classLabel>
<newAxiom>'Adequate Surgical Margin Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201481</classIRI>
<classLabel>Age at First Oral Sex</classLabel>
<newAxiom>'Age at First Oral Sex' SubClassOf 'Age'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201480</classIRI>
<classLabel>Age at First Sexual Intercourse</classLabel>
<newAxiom>'Age at First Sexual Intercourse' SubClassOf 'Age'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201486</classIRI>
<classLabel>Millimeter Mercury times Minute per Liter times Square Meter</classLabel>
<newAxiom>'Millimeter Mercury times Minute per Liter times Square Meter' SubClassOf 'Unit for Functional Test Results'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201485</classIRI>
<classLabel>Picomole per Punch Observational Unit per Hour</classLabel>
<newAxiom>'Picomole per Punch Observational Unit per Hour' SubClassOf 'Molality Unit'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201484</classIRI>
<classLabel>Mass Balance Study</classLabel>
<newAxiom>'Mass Balance Study' SubClassOf 'Human Pharmacology Study'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201479</classIRI>
<classLabel>Number of Oral Sexual Partners</classLabel>
<newAxiom>'Number of Oral Sexual Partners' SubClassOf 'Total Number of Sexual Partners'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201478</classIRI>
<classLabel>Number of Female Sexual Partners</classLabel>
<newAxiom>'Number of Female Sexual Partners' SubClassOf 'Total Number of Sexual Partners'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201477</classIRI>
<classLabel>Number of Male Sexual Partners</classLabel>
<newAxiom>'Number of Male Sexual Partners' SubClassOf 'Total Number of Sexual Partners'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201476</classIRI>
<classLabel>Number of New Oral Sexual Partners</classLabel>
<newAxiom>'Number of New Oral Sexual Partners' SubClassOf 'Total Number of Sexual Partners'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201471</classIRI>
<classLabel>Forced Expiratory Time</classLabel>
<newAxiom>'Forced Expiratory Time' SubClassOf 'Expiratory Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201470</classIRI>
<classLabel>Biological Nephew</classLabel>
<newAxiom>'Biological Nephew' SubClassOf 'Nephew'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201475</classIRI>
<classLabel>Number of New Female Sexual Partners</classLabel>
<newAxiom>'Number of New Female Sexual Partners' SubClassOf 'Total Number of Sexual Partners'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201474</classIRI>
<classLabel>Number of New Male Sexual Partners</classLabel>
<newAxiom>'Number of New Male Sexual Partners' SubClassOf 'Total Number of Sexual Partners'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201473</classIRI>
<classLabel>Lung Clearance Index to 2.5% Initial Concentration</classLabel>
<newAxiom>'Lung Clearance Index to 2.5% Initial Concentration' SubClassOf 'Lung Clearance Index'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201472</classIRI>
<classLabel>Lung Clearance Index to 5% Initial Concentration</classLabel>
<newAxiom>'Lung Clearance Index to 5% Initial Concentration' SubClassOf 'Lung Clearance Index'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201468</classIRI>
<classLabel>Log Arbitrary Concentration</classLabel>
<newAxiom>'Log Arbitrary Concentration' SubClassOf 'Concentration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201467</classIRI>
<classLabel>Log Number Concentration</classLabel>
<newAxiom>'Log Number Concentration' SubClassOf 'Concentration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201466</classIRI>
<classLabel>Allogeneic Stem Cell Transplantation</classLabel>
<newAxiom>'Allogeneic Stem Cell Transplantation' SubClassOf 'Stem Cell Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201465</classIRI>
<classLabel>Autologous Stem Cell Transplantation</classLabel>
<newAxiom>'Autologous Stem Cell Transplantation' SubClassOf 'Stem Cell Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201469</classIRI>
<classLabel>Threshold Number</classLabel>
<newAxiom>'Threshold Number' SubClassOf 'Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201499</classIRI>
<classLabel>EGFR-targeted IL-2/IL-10 Dual Cytokine Fusion Protein DK210 (EGFR)</classLabel>
<newAxiom>'EGFR-targeted IL-2/IL-10 Dual Cytokine Fusion Protein DK210 (EGFR)' SubClassOf 'Immunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201498</classIRI>
<classLabel>Hematologic Improvement</classLabel>
<newAxiom>'Hematologic Improvement' SubClassOf 'Hematologic Response'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201493</classIRI>
<classLabel>Anti-CD123 CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-CD123 CAR T Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Anti-CD123 CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201492</classIRI>
<classLabel>Anti-B7-H3 CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-B7-H3 CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Anti-B7-H3 CAR T Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201491</classIRI>
<classLabel>Anti-GD2 CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-GD2 CAR T Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Anti-GD2 CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201490</classIRI>
<classLabel>Liposomal iNKT Agonist PORT-2</classLabel>
<newAxiom>'Liposomal iNKT Agonist PORT-2' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201497</classIRI>
<classLabel>Anti-HER2 CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-HER2 CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201496</classIRI>
<classLabel>RNA-lipoplex Cancer Vaccine BNT116</classLabel>
<newAxiom>'RNA-lipoplex Cancer Vaccine BNT116' SubClassOf 'mRNA Cancer Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201495</classIRI>
<classLabel>Anti-CD33 CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-CD33 CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Anti-CD33 CAR T Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201494</classIRI>
<classLabel>Complete Response without Minimal Residual Disease</classLabel>
<newAxiom>'Complete Response without Minimal Residual Disease' SubClassOf 'Complete Remission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201489</classIRI>
<classLabel>Palliative Care Unit Stay</classLabel>
<newAxiom>'Palliative Care Unit Stay' SubClassOf 'Inpatient Encounter'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201488</classIRI>
<classLabel>Short Term Acute Care Stay</classLabel>
<newAxiom>'Short Term Acute Care Stay' SubClassOf 'Inpatient Acute Care Encounter'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201487</classIRI>
<classLabel>Centimeter of Water per Milliliter per Second</classLabel>
<newAxiom>'Centimeter of Water per Milliliter per Second' SubClassOf 'Manometric Unit of Pressure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201512</classIRI>
<classLabel>Anti-PVRIG Monoclonal Antibody</classLabel>
<newAxiom>'Anti-PVRIG Monoclonal Antibody' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201511</classIRI>
<classLabel>Anti-CD123 Monoclonal Antibody</classLabel>
<newAxiom>'Anti-CD123 Monoclonal Antibody' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201510</classIRI>
<classLabel>Anti-CD38 CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-CD38 CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201516</classIRI>
<classLabel>Anti-B7-H3 Antibody-drug Conjugate</classLabel>
<newAxiom>'Anti-B7-H3 Antibody-drug Conjugate' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201515</classIRI>
<classLabel>ATM Kinase Inhibitor WSD-0628</classLabel>
<newAxiom>'ATM Kinase Inhibitor WSD-0628' SubClassOf 'Serine/Threonine Kinase Inhibitor'</newAxiom>
<newAxiom>'ATM Kinase Inhibitor WSD-0628' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201514</classIRI>
<classLabel>Developmental and Epileptic Encephalopathy 47</classLabel>
<newAxiom>'Developmental and Epileptic Encephalopathy 47' SubClassOf 'Disease_Mapped_To_Gene' some 'FGF12 Gene'</newAxiom>
<newAxiom>'Developmental and Epileptic Encephalopathy 47' SubClassOf 'Developmental and Epileptic Encephalopathy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201513</classIRI>
<classLabel>Anti-CD30 CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-CD30 CAR T Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Anti-CD30 CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201519</classIRI>
<classLabel>Parkinson Disease 14, Autosomal Recessive</classLabel>
<newAxiom>'Parkinson Disease 14, Autosomal Recessive' SubClassOf 'Parkinson's Disease'</newAxiom>
<newAxiom>'Parkinson Disease 14, Autosomal Recessive' SubClassOf 'Disease_Mapped_To_Gene' some 'PLA2G6 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201518</classIRI>
<classLabel>Developmental and Epileptic Encephalopathy 65</classLabel>
<newAxiom>'Developmental and Epileptic Encephalopathy 65' SubClassOf 'Developmental and Epileptic Encephalopathy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201517</classIRI>
<classLabel>Mean Cell-free Circulating Tumor DNA Molecules per Milliliter</classLabel>
<newAxiom>'Mean Cell-free Circulating Tumor DNA Molecules per Milliliter' SubClassOf 'DNA Copies per Milliliter'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201500</classIRI>
<classLabel>Adverse Events End Relative to Reference Time Point</classLabel>
<newAxiom>'Adverse Events End Relative to Reference Time Point' SubClassOf 'Retired Concept Current Year'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201505</classIRI>
<classLabel>Procedure Agents End Relative to Reference Time Point</classLabel>
<newAxiom>'Procedure Agents End Relative to Reference Time Point' SubClassOf 'End Relative to Reference Time Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201504</classIRI>
<classLabel>Microbiology Susceptibility End Relative to Reference Time Point</classLabel>
<newAxiom>'Microbiology Susceptibility End Relative to Reference Time Point' SubClassOf 'End Relative to Reference Time Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201503</classIRI>
<classLabel>Morphology End Relative to Reference Time Point</classLabel>
<newAxiom>'Morphology End Relative to Reference Time Point' SubClassOf 'End Relative to Reference Time Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201509</classIRI>
<classLabel>Disease Response and Clinical Classification End Relative to Reference Time Point</classLabel>
<newAxiom>'Disease Response and Clinical Classification End Relative to Reference Time Point' SubClassOf 'End Relative to Reference Time Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201508</classIRI>
<classLabel>Substance Use End Relative to Reference Time Point</classLabel>
<newAxiom>'Substance Use End Relative to Reference Time Point' SubClassOf 'Retired Concept Current Year'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201507</classIRI>
<classLabel>Meal Data End Relative to Reference Time Point</classLabel>
<newAxiom>'Meal Data End Relative to Reference Time Point' SubClassOf 'End Relative to Reference Time Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201506</classIRI>
<classLabel>Concomitant/Prior Medications End Relative to Reference Time Point</classLabel>
<newAxiom>'Concomitant/Prior Medications End Relative to Reference Time Point' SubClassOf 'Retired Concept Current Year'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201321</classIRI>
<classLabel>Biomedical Concept Surrogate Reference</classLabel>
<newAxiom>'Biomedical Concept Surrogate Reference' SubClassOf 'Reference'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201320</classIRI>
<classLabel>Biomedical Concept Surrogate Description</classLabel>
<newAxiom>'Biomedical Concept Surrogate Description' SubClassOf 'Description'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201314</classIRI>
<classLabel>Biomedical Concept Synonym</classLabel>
<newAxiom>'Biomedical Concept Synonym' SubClassOf 'Synonym'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201313</classIRI>
<classLabel>Biomedical Concept Reference</classLabel>
<newAxiom>'Biomedical Concept Reference' SubClassOf 'Reference'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201312</classIRI>
<classLabel>Biomedical Concept Name</classLabel>
<newAxiom>'Biomedical Concept Name' SubClassOf 'Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201311</classIRI>
<classLabel>Address Full Text</classLabel>
<newAxiom>'Address Full Text' SubClassOf 'Text'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201318</classIRI>
<classLabel>Biomedical Concept Property Concept Code</classLabel>
<newAxiom>'Biomedical Concept Property Concept Code' SubClassOf 'Category Code'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201317</classIRI>
<classLabel>Biomedical Concept Category Name</classLabel>
<newAxiom>'Biomedical Concept Category Name' SubClassOf 'Category Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201316</classIRI>
<classLabel>Biomedical Concept Category Description</classLabel>
<newAxiom>'Biomedical Concept Category Description' SubClassOf 'Description'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201315</classIRI>
<classLabel>Biomedical Concept Category Code</classLabel>
<newAxiom>'Biomedical Concept Category Code' SubClassOf 'Category Code'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201319</classIRI>
<classLabel>Biomedical Concept Property Response Data Type</classLabel>
<newAxiom>'Biomedical Concept Property Response Data Type' SubClassOf 'Data Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201310</classIRI>
<classLabel>Study Activity is Optional Reason</classLabel>
<newAxiom>'Study Activity is Optional Reason' SubClassOf 'Reason'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201303</classIRI>
<classLabel>Response Biomarker</classLabel>
<newAxiom>'Response Biomarker' SubClassOf 'Biomarker'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201302</classIRI>
<classLabel>Memory Cytotoxic T-Lymphocyte Subpopulation Count</classLabel>
<newAxiom>'Memory Cytotoxic T-Lymphocyte Subpopulation Count' SubClassOf 'Memory Cytotoxic T-Lymphocyte Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201301</classIRI>
<classLabel>Memory Cytotoxic T-Lymphocyte Count</classLabel>
<newAxiom>'Memory Cytotoxic T-Lymphocyte Count' SubClassOf 'Cytotoxic T-Lymphocyte Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201300</classIRI>
<classLabel>IDH1 Inhibitor TQB3454</classLabel>
<newAxiom>'IDH1 Inhibitor TQB3454' SubClassOf 'IDH1 inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201307</classIRI>
<classLabel>Study Activity is Conditional Indicator</classLabel>
<newAxiom>'Study Activity is Conditional Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201306</classIRI>
<classLabel>Rheumatoid Factor Autoantibody Measurement</classLabel>
<newAxiom>'Rheumatoid Factor Autoantibody Measurement' SubClassOf 'Rheumatoid Factor Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201305</classIRI>
<classLabel>Neuronal Nuclear Autoantigens</classLabel>
<newAxiom>'Neuronal Nuclear Autoantigens' SubClassOf 'Autoantigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201304</classIRI>
<classLabel>Basement Membrane Antigens</classLabel>
<newAxiom>'Basement Membrane Antigens' SubClassOf 'Autoantigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201309</classIRI>
<classLabel>Study Activity is Optional Indicator</classLabel>
<newAxiom>'Study Activity is Optional Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201308</classIRI>
<classLabel>Study Activity is Conditional Reason</classLabel>
<newAxiom>'Study Activity is Conditional Reason' SubClassOf 'Reason'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201343</classIRI>
<classLabel>Upper Timing Window</classLabel>
<newAxiom>'Upper Timing Window' SubClassOf 'Window'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201342</classIRI>
<classLabel>Lower Timing Window</classLabel>
<newAxiom>'Lower Timing Window' SubClassOf 'Window'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201341</classIRI>
<classLabel>Timing Value</classLabel>
<newAxiom>'Timing Value' SubClassOf 'Value'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201340</classIRI>
<classLabel>Transition Start Rule</classLabel>
<newAxiom>'Transition Start Rule' SubClassOf 'Start Rule'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201336</classIRI>
<classLabel>Schedule Sequence Number</classLabel>
<newAxiom>'Schedule Sequence Number' SubClassOf 'Sequence Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201335</classIRI>
<classLabel>Condition Assignments</classLabel>
<newAxiom>'Condition Assignments' SubClassOf 'Assignment'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201334</classIRI>
<classLabel>Schedule Timeline Name</classLabel>
<newAxiom>'Schedule Timeline Name' SubClassOf 'Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201333</classIRI>
<classLabel>Schedule Timeline Entry Condition</classLabel>
<newAxiom>'Schedule Timeline Entry Condition' SubClassOf 'Logical Condition'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201339</classIRI>
<classLabel>Transition End Rule</classLabel>
<newAxiom>'Transition End Rule' SubClassOf 'End Rule'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201338</classIRI>
<classLabel>Study Design Name</classLabel>
<newAxiom>'Study Design Name' SubClassOf 'Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201337</classIRI>
<classLabel>Scheduled Instance Type</classLabel>
<newAxiom>'Scheduled Instance Type' SubClassOf 'Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201332</classIRI>
<classLabel>Schedule Timeline Description</classLabel>
<newAxiom>'Schedule Timeline Description' SubClassOf 'Description'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201331</classIRI>
<classLabel>Main Timeline Indicator</classLabel>
<newAxiom>'Main Timeline Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201330</classIRI>
<classLabel>Response Code Enabled Indicator</classLabel>
<newAxiom>'Response Code Enabled Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201325</classIRI>
<classLabel>Procedure Name</classLabel>
<newAxiom>'Procedure Name' SubClassOf 'Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201324</classIRI>
<classLabel>Procedure Description</classLabel>
<newAxiom>'Procedure Description' SubClassOf 'Description'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201323</classIRI>
<classLabel>Variable of Interest for the Estimand</classLabel>
<newAxiom>'Variable of Interest for the Estimand' SubClassOf 'Study Variable'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201322</classIRI>
<classLabel>Business Therapeutic Areas</classLabel>
<newAxiom>'Business Therapeutic Areas' SubClassOf 'Therapeutic Area'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201329</classIRI>
<classLabel>Study Procedure is Optional Reason</classLabel>
<newAxiom>'Study Procedure is Optional Reason' SubClassOf 'Reason'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201328</classIRI>
<classLabel>Study Procedure is Optional Indicator</classLabel>
<newAxiom>'Study Procedure is Optional Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201327</classIRI>
<classLabel>Study Procedure is Conditional Reason</classLabel>
<newAxiom>'Study Procedure is Conditional Reason' SubClassOf 'Reason'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201326</classIRI>
<classLabel>Study Procedure is Conditional Indicator</classLabel>
<newAxiom>'Study Procedure is Conditional Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201361</classIRI>
<classLabel>Diagnostic Biomarker</classLabel>
<newAxiom>'Diagnostic Biomarker' SubClassOf 'Biomarker'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201360</classIRI>
<classLabel>Susceptibility Biomarker</classLabel>
<newAxiom>'Susceptibility Biomarker' SubClassOf 'Biomarker'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201365</classIRI>
<classLabel>Pharmacodynamic Biomarker</classLabel>
<newAxiom>'Pharmacodynamic Biomarker' SubClassOf 'Response Biomarker'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201364</classIRI>
<classLabel>Predictive Biomarker</classLabel>
<newAxiom>'Predictive Biomarker' SubClassOf 'Biomarker'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201363</classIRI>
<classLabel>Prognostic Biomarker</classLabel>
<newAxiom>'Prognostic Biomarker' SubClassOf 'Biomarker'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201362</classIRI>
<classLabel>Monitoring Biomarker</classLabel>
<newAxiom>'Monitoring Biomarker' SubClassOf 'Biomarker'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201358</classIRI>
<classLabel>Fixed Reference Timing Type</classLabel>
<newAxiom>'Fixed Reference Timing Type' SubClassOf 'Timing Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201357</classIRI>
<classLabel>Before Timing Type</classLabel>
<newAxiom>'Before Timing Type' SubClassOf 'Timing Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201356</classIRI>
<classLabel>After Timing Type</classLabel>
<newAxiom>'After Timing Type' SubClassOf 'Timing Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201355</classIRI>
<classLabel>Start to Start</classLabel>
<newAxiom>'Start to Start' SubClassOf 'Timing Relative To From Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201359</classIRI>
<classLabel>Biomarker Category</classLabel>
<newAxiom>'Biomarker Category' SubClassOf 'Category'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201350</classIRI>
<classLabel>Scheduled Activity Instance</classLabel>
<newAxiom>'Scheduled Activity Instance' SubClassOf 'Scheduled Instance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201354</classIRI>
<classLabel>Start to End</classLabel>
<newAxiom>'Start to End' SubClassOf 'Timing Relative To From Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201353</classIRI>
<classLabel>End to Start</classLabel>
<newAxiom>'End to Start' SubClassOf 'Timing Relative To From Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201352</classIRI>
<classLabel>End to End</classLabel>
<newAxiom>'End to End' SubClassOf 'Timing Relative To From Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201351</classIRI>
<classLabel>Scheduled Decision Instance</classLabel>
<newAxiom>'Scheduled Decision Instance' SubClassOf 'Scheduled Instance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201347</classIRI>
<classLabel>Response Code</classLabel>
<newAxiom>'Response Code' SubClassOf 'Code'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201346</classIRI>
<classLabel>Biomedical Concept Category</classLabel>
<newAxiom>'Biomedical Concept Category' SubClassOf 'Category'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201345</classIRI>
<classLabel>Biomedical Concept</classLabel>
<newAxiom>'Biomedical Concept' SubClassOf 'Concept'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201344</classIRI>
<classLabel>Alias Code</classLabel>
<newAxiom>'Alias Code' SubClassOf 'Code'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201349</classIRI>
<classLabel>Schedule Timeline Exit</classLabel>
<newAxiom>'Schedule Timeline Exit' SubClassOf 'Exit'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201348</classIRI>
<classLabel>Schedule Timeline</classLabel>
<newAxiom>'Schedule Timeline' SubClassOf 'Timeline'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201383</classIRI>
<classLabel>Laboratory Encounter</classLabel>
<newAxiom>'Laboratory Encounter' SubClassOf 'Outpatient Encounter'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201382</classIRI>
<classLabel>Home Hospice Visit</classLabel>
<newAxiom>'Home Hospice Visit' SubClassOf 'Home Healthcare Visit'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201381</classIRI>
<classLabel>Paroxysmal Atrial Flutter</classLabel>
<newAxiom>'Paroxysmal Atrial Flutter' SubClassOf 'Atrial Flutter by ECG Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201380</classIRI>
<classLabel>Persistent Atrial Flutter</classLabel>
<newAxiom>'Persistent Atrial Flutter' SubClassOf 'Atrial Flutter by ECG Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201387</classIRI>
<classLabel>Histoplasma capsulatum M Antigen</classLabel>
<newAxiom>'Histoplasma capsulatum M Antigen' SubClassOf 'Non-Human Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201386</classIRI>
<classLabel>Histoplasma capsulatum H Antigen</classLabel>
<newAxiom>'Histoplasma capsulatum H Antigen' SubClassOf 'Non-Human Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201385</classIRI>
<classLabel>Epstein-Barr Virus Early Antigen</classLabel>
<newAxiom>'Epstein-Barr Virus Early Antigen' SubClassOf 'Viral Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201384</classIRI>
<classLabel>Imaging Center Encounter</classLabel>
<newAxiom>'Imaging Center Encounter' SubClassOf 'Outpatient Encounter'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201379</classIRI>
<classLabel>Every Eight Years</classLabel>
<newAxiom>'Every Eight Years' SubClassOf 'Schedule Frequency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201378</classIRI>
<classLabel>Respiratory Rate Device Setting</classLabel>
<newAxiom>'Respiratory Rate Device Setting' SubClassOf 'Device Setting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201377</classIRI>
<classLabel>Tidal Volume Device Setting</classLabel>
<newAxiom>'Tidal Volume Device Setting' SubClassOf 'Device Setting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201372</classIRI>
<classLabel>CD134 Expression Measurement</classLabel>
<newAxiom>'CD134 Expression Measurement' SubClassOf 'Cluster of Differentiation Expression Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201371</classIRI>
<classLabel>Memory Helper T-Lymphocyte to Helper T-Lymphocyte Ratio Measurement</classLabel>
<newAxiom>'Memory Helper T-Lymphocyte to Helper T-Lymphocyte Ratio Measurement' SubClassOf 'Memory Helper T-Lymphocyte Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201370</classIRI>
<classLabel>Memory Helper T-Lymphocyte Subpopulation to Memory Helper T-Lymphocyte Ratio Measurement</classLabel>
<newAxiom>'Memory Helper T-Lymphocyte Subpopulation to Memory Helper T-Lymphocyte Ratio Measurement' SubClassOf 'Memory Helper T-Lymphocyte Subpopulation to Helper T-Lymphocyte Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201376</classIRI>
<classLabel>Positive End Expiratory Pressure Device Setting</classLabel>
<newAxiom>'Positive End Expiratory Pressure Device Setting' SubClassOf 'Device Setting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201375</classIRI>
<classLabel>Pressure Support Device Setting</classLabel>
<newAxiom>'Pressure Support Device Setting' SubClassOf 'Device Setting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201374</classIRI>
<classLabel>Ventilator Mode</classLabel>
<newAxiom>'Ventilator Mode' SubClassOf 'Device Setting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201373</classIRI>
<classLabel>Central Memory Cytotoxic T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement</classLabel>
<newAxiom>'Central Memory Cytotoxic T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement' SubClassOf 'Central Memory Cytotoxic T-Lymphocyte Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201369</classIRI>
<classLabel>Memory Cytotoxic T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement</classLabel>
<newAxiom>'Memory Cytotoxic T-Lymphocyte to Cytotoxic T-Lymphocyte Ratio Measurement' SubClassOf 'Blood Cell Count Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201368</classIRI>
<classLabel>Memory Cytotoxic T-Lymphocyte Subpopulation to Memory Cytotoxic T-Lymphocyte Ratio Measurement</classLabel>
<newAxiom>'Memory Cytotoxic T-Lymphocyte Subpopulation to Memory Cytotoxic T-Lymphocyte Ratio Measurement' SubClassOf 'Memory Cytotoxic T-Lymphocyte Subpopulation Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201367</classIRI>
<classLabel>Safety Biomarker</classLabel>
<newAxiom>'Safety Biomarker' SubClassOf 'Biomarker'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201366</classIRI>
<classLabel>Surrogate Endpoint Biomarker</classLabel>
<newAxiom>'Surrogate Endpoint Biomarker' SubClassOf 'Response Biomarker'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201399</classIRI>
<classLabel>Japanese Cedar Pollen Antigen</classLabel>
<newAxiom>'Japanese Cedar Pollen Antigen' SubClassOf 'Allergen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201390</classIRI>
<classLabel>Striated Muscle Autoantigens</classLabel>
<newAxiom>'Striated Muscle Autoantigens' SubClassOf 'Autoantigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201394</classIRI>
<classLabel>Neuronal Nuclear Type 1 Autoantigens</classLabel>
<newAxiom>'Neuronal Nuclear Type 1 Autoantigens' SubClassOf 'Neuronal Nuclear Autoantigens'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201393</classIRI>
<classLabel>Perennial Ryegrass Pollen Antigen</classLabel>
<newAxiom>'Perennial Ryegrass Pollen Antigen' SubClassOf 'Allergen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201392</classIRI>
<classLabel>Kentucky Bluegrass Pollen Antigen</classLabel>
<newAxiom>'Kentucky Bluegrass Pollen Antigen' SubClassOf 'Allergen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201391</classIRI>
<classLabel>Liver Kidney Microsomal Antigens</classLabel>
<newAxiom>'Liver Kidney Microsomal Antigens' SubClassOf 'Autoantigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201398</classIRI>
<classLabel>Mugwort Pollen Antigen</classLabel>
<newAxiom>'Mugwort Pollen Antigen' SubClassOf 'Allergen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201397</classIRI>
<classLabel>Purkinje Cell Cytoplasmic Type 1 Antigens</classLabel>
<newAxiom>'Purkinje Cell Cytoplasmic Type 1 Antigens' SubClassOf 'Autoantigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201396</classIRI>
<classLabel>Purkinje Cell Autoantigens</classLabel>
<newAxiom>'Purkinje Cell Autoantigens' SubClassOf 'Neuronal Nuclear Autoantigens'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201395</classIRI>
<classLabel>Neuronal Nuclear Type 2 Autoantigens</classLabel>
<newAxiom>'Neuronal Nuclear Type 2 Autoantigens' SubClassOf 'Neuronal Nuclear Autoantigens'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201389</classIRI>
<classLabel>Vesicular Stomatitis Indiana Virus Glycoprotein</classLabel>
<newAxiom>'Vesicular Stomatitis Indiana Virus Glycoprotein' SubClassOf 'ENV Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201388</classIRI>
<classLabel>Adrenal Autoantigens</classLabel>
<newAxiom>'Adrenal Autoantigens' SubClassOf 'Autoantigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201200</classIRI>
<classLabel>FXN wt Allele</classLabel>
<newAxiom>'FXN wt Allele' EquivalentTo 'FXN Gene' and ('Gene_Is_Element_In_Pathway' some 'Porphyrin and Chlorophyll Metabolism Pathway') and ('Gene_Is_Element_In_Pathway' some 'HIF-2-Alpha Transcription Factor Pathway') and ('Gene_In_Chromosomal_Location' some '9q21.11')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201222</classIRI>
<classLabel>Immunoglobulin Heavy Constant Gamma 2</classLabel>
<newAxiom>'Immunoglobulin Heavy Constant Gamma 2' EquivalentTo 'Immunoprotein' and ('Gene_Product_Has_Chemical_Classification' some 'Immunoglobulin Family Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Immunoglobulin Constant Region') and ('Gene_Product_Is_Physical_Part_Of' some 'Immunoglobulin Heavy Chain') and ('Gene_Product_Is_Physical_Part_Of' some 'Immunoglobulin') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Humoral Immunity') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Antigen Binding') and ('Gene_Product_Encoded_By_Gene' some 'IGHG2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201221</classIRI>
<classLabel>IGHG2 wt Allele</classLabel>
<newAxiom>'IGHG2 wt Allele' SubClassOf 'IGHG2 Gene'</newAxiom>
<newAxiom>'IGHG2 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '14q32.33'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201220</classIRI>
<classLabel>IGHG2 Gene</classLabel>
<newAxiom>'IGHG2 Gene' SubClassOf 'Immunoprotein Gene'</newAxiom>
<newAxiom>'IGHG2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Antigen Binding'</newAxiom>
<newAxiom>'IGHG2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Humoral Immunity'</newAxiom>
<newAxiom>'IGHG2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immune Response Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201215</classIRI>
<classLabel>Ex-vivo T-Cell and B-Cell Depletion</classLabel>
<newAxiom>'Ex-vivo T-Cell and B-Cell Depletion' SubClassOf 'Ex-vivo T-Cell Depletion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201214</classIRI>
<classLabel>Immunoglobulin Heavy Constant Delta</classLabel>
<newAxiom>'Immunoglobulin Heavy Constant Delta' EquivalentTo 'Immunoprotein' and ('Gene_Product_Has_Chemical_Classification' some 'Immunoglobulin Family Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Immunoglobulin Constant Region') and ('Gene_Product_Is_Physical_Part_Of' some 'Immunoglobulin Heavy Chain') and ('Gene_Product_Is_Physical_Part_Of' some 'Immunoglobulin') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Humoral Immunity') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Signal Transduction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Receptor Signaling') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Antigen Binding') and ('Gene_Product_Encoded_By_Gene' some 'IGHD Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201213</classIRI>
<classLabel>IGHD wt Allele</classLabel>
<newAxiom>'IGHD wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '14q32.33'</newAxiom>
<newAxiom>'IGHD wt Allele' SubClassOf 'IGHD Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201212</classIRI>
<classLabel>IGHD Gene</classLabel>
<newAxiom>'IGHD Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immune Response Process'</newAxiom>
<newAxiom>'IGHD Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Receptor Signaling'</newAxiom>
<newAxiom>'IGHD Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Humoral Immunity'</newAxiom>
<newAxiom>'IGHD Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Antigen Binding'</newAxiom>
<newAxiom>'IGHD Gene' SubClassOf 'Immunoprotein Gene'</newAxiom>
<newAxiom>'IGHD Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Signal Transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201219</classIRI>
<classLabel>CD3+/CD19+ Cell-depleted Autologous Hematopoietic Stem Cells</classLabel>
<newAxiom>'CD3+/CD19+ Cell-depleted Autologous Hematopoietic Stem Cells' SubClassOf 'Therapeutic Hematopoietic Stem Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201218</classIRI>
<classLabel>YTH Domain-Containing Protein 1</classLabel>
<newAxiom>'YTH Domain-Containing Protein 1' EquivalentTo 'RNA Binding Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleoplasm') and ('Gene_Product_Has_Biochemical_Function' some 'Transport Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Splicing') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'mRNA Export') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'X-Chromosome Inactivation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Polyadenylation Regulation') and ('Gene_Product_Encoded_By_Gene' some 'YTHDC1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201217</classIRI>
<classLabel>YTHDC1 wt Allele</classLabel>
<newAxiom>'YTHDC1 wt Allele' SubClassOf 'YTHDC1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201216</classIRI>
<classLabel>YTHDC1 Gene</classLabel>
<newAxiom>'YTHDC1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'mRNA Export'</newAxiom>
<newAxiom>'YTHDC1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Splicing'</newAxiom>
<newAxiom>'YTHDC1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Polyadenylation Regulation'</newAxiom>
<newAxiom>'YTHDC1 Gene' SubClassOf 'mRNA Transport Gene'</newAxiom>
<newAxiom>'YTHDC1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Binding'</newAxiom>
<newAxiom>'YTHDC1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'X-Chromosome Inactivation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201211</classIRI>
<classLabel>UGT1A1 Inhibitor</classLabel>
<newAxiom>'UGT1A1 Inhibitor' SubClassOf 'Substance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201210</classIRI>
<classLabel>Ventral Surface of Tongue</classLabel>
<newAxiom>'Ventral Surface of Tongue' SubClassOf 'Organ of Special Sense Part'</newAxiom>
<newAxiom>'Ventral Surface of Tongue' SubClassOf 'Head and Neck Part'</newAxiom>
<newAxiom>'Ventral Surface of Tongue' SubClassOf 'Anatomic_Structure_Is_Physical_Part_Of' some 'Tongue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201204</classIRI>
<classLabel>Myeloma-Overexpressed Gene Protein</classLabel>
<newAxiom>'Myeloma-Overexpressed Gene Protein' SubClassOf 'Regulatory Protein'</newAxiom>
<newAxiom>'Myeloma-Overexpressed Gene Protein' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'MYEOV Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201203</classIRI>
<classLabel>MYEOV wt Allele</classLabel>
<newAxiom>'MYEOV wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '11q13.3'</newAxiom>
<newAxiom>'MYEOV wt Allele' SubClassOf 'MYEOV Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201202</classIRI>
<classLabel>MYEOV Gene</classLabel>
<newAxiom>'MYEOV Gene' SubClassOf 'Regulatory Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201201</classIRI>
<classLabel>Frataxin, Mitochondrial</classLabel>
<newAxiom>'Frataxin, Mitochondrial' EquivalentTo 'Oxidoreductase' and ('Gene_Product_Is_Element_In_Pathway' some 'Porphyrin and Chlorophyll Metabolism Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'HIF-2-Alpha Transcription Factor Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Mitochondrial Matrix') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Biosynthetic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Respiration') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transmembrane Transport') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Ion Transport Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Iron Chelation') and ('Gene_Product_Encoded_By_Gene' some 'FXN Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201208</classIRI>
<classLabel>Border of Tongue</classLabel>
<newAxiom>'Border of Tongue' SubClassOf 'Anatomic_Structure_Is_Physical_Part_Of' some 'Tongue'</newAxiom>
<newAxiom>'Border of Tongue' SubClassOf 'Organ of Special Sense Part'</newAxiom>
<newAxiom>'Border of Tongue' SubClassOf 'Head and Neck Part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201207</classIRI>
<classLabel>STING Agonist BI 1387446</classLabel>
<newAxiom>'STING Agonist BI 1387446' SubClassOf 'STING Agonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201206</classIRI>
<classLabel>BCDX2 Complex</classLabel>
<newAxiom>'BCDX2 Complex' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Homologous Recombination'</newAxiom>
<newAxiom>'BCDX2 Complex' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Recombination Repair'</newAxiom>
<newAxiom>'BCDX2 Complex' SubClassOf 'DNA Repair Complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201209</classIRI>
<classLabel>pan-PIM Kinase Inhibitor GDC-0570</classLabel>
<newAxiom>'pan-PIM Kinase Inhibitor GDC-0570' SubClassOf 'Serine/Threonine Kinase Inhibitor'</newAxiom>
<newAxiom>'pan-PIM Kinase Inhibitor GDC-0570' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201240</classIRI>
<classLabel>Derlin-1</classLabel>
<newAxiom>'Derlin-1' EquivalentTo 'Transport Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Amyotrophic Lateral Sclerosis Pathway') and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Endoplasmic Reticulum') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Unfolded Protein Response') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Protein Interaction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Subcellular Protein Targeting') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Degradation Induction') and ('Gene_Product_Encoded_By_Gene' some 'DERL1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201244</classIRI>
<classLabel>Anti-gremlin-1 Monoclonal Antibody TST003</classLabel>
<newAxiom>'Anti-gremlin-1 Monoclonal Antibody TST003' SubClassOf 'Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-gremlin-1 Monoclonal Antibody TST003' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201243</classIRI>
<classLabel>Acetylcholinesterase</classLabel>
<newAxiom>'Acetylcholinesterase' EquivalentTo 'Esterase' and ('Gene_Product_Is_Element_In_Pathway' some 'Glycerophospholipid Metabolism Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'ATF-2 Transcription Factor Signaling Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Associated_Anatomy' some 'Chemical Synapse') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Apoptosis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Metabolic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Signal Transduction Inhibition') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Neurotransmitter Activity Inhibition') and ('Gene_Product_Encoded_By_Gene' some 'ACHE Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201242</classIRI>
<classLabel>ACHE wt Allele</classLabel>
<newAxiom>'ACHE wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'ATF-2 Transcription Factor Signaling Pathway'</newAxiom>
<newAxiom>'ACHE wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '7q21.1'</newAxiom>
<newAxiom>'ACHE wt Allele' SubClassOf 'ACHE Gene'</newAxiom>
<newAxiom>'ACHE wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Glycerophospholipid Metabolism Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201241</classIRI>
<classLabel>ACHE Gene</classLabel>
<newAxiom>'ACHE Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Neurotransmitter Activity Inhibition'</newAxiom>
<newAxiom>'ACHE Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Metabolic Process'</newAxiom>
<newAxiom>'ACHE Gene' SubClassOf 'Esterase Gene'</newAxiom>
<newAxiom>'ACHE Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Signal Transduction Inhibition'</newAxiom>
<newAxiom>'ACHE Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Apoptosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201236</classIRI>
<classLabel>Anti-PD-L1/PD-L2 Bispecific Antibody IMGS-001</classLabel>
<newAxiom>'Anti-PD-L1/PD-L2 Bispecific Antibody IMGS-001' SubClassOf 'Anti-PD-L1 Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-PD-L1/PD-L2 Bispecific Antibody IMGS-001' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-PD-L1/PD-L2 Bispecific Antibody IMGS-001' SubClassOf 'Bispecific Antibody'</newAxiom>
<newAxiom>'Anti-PD-L1/PD-L2 Bispecific Antibody IMGS-001' SubClassOf 'PD-L2 Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201235</classIRI>
<classLabel>Beta-catenin Inhibitor FOG-001</classLabel>
<newAxiom>'Beta-catenin Inhibitor FOG-001' SubClassOf 'Signal Transduction Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201234</classIRI>
<classLabel>Sodium-Coupled Neutral Amino Acid Symporter 2</classLabel>
<newAxiom>'Sodium-Coupled Neutral Amino Acid Symporter 2' EquivalentTo 'Transport Protein' and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Solute Carrier Family') and ('Gene_Product_Has_Biochemical_Function' some 'Amino Acid Transporter') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transmembrane Transport') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Neuronal Transmission') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Ion Transport Process') and ('Gene_Product_Encoded_By_Gene' some 'SLC38A2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201239</classIRI>
<classLabel>DERL1 wt Allele</classLabel>
<newAxiom>'DERL1 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Amyotrophic Lateral Sclerosis Pathway'</newAxiom>
<newAxiom>'DERL1 wt Allele' SubClassOf 'DERL1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201238</classIRI>
<classLabel>DERL1 Gene</classLabel>
<newAxiom>'DERL1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Subcellular Protein Targeting'</newAxiom>
<newAxiom>'DERL1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Degradation Induction'</newAxiom>
<newAxiom>'DERL1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Unfolded Protein Response'</newAxiom>
<newAxiom>'DERL1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein-Protein Interaction'</newAxiom>
<newAxiom>'DERL1 Gene' SubClassOf 'Trafficking Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201233</classIRI>
<classLabel>SLC38A2 wt Allele</classLabel>
<newAxiom>'SLC38A2 wt Allele' SubClassOf 'SLC38A2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201231</classIRI>
<classLabel>SLC38A2 Gene</classLabel>
<newAxiom>'SLC38A2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transmembrane Transport'</newAxiom>
<newAxiom>'SLC38A2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Ion Transport Process'</newAxiom>
<newAxiom>'SLC38A2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Neuronal Transmission'</newAxiom>
<newAxiom>'SLC38A2 Gene' SubClassOf 'Transport Protein Gene'</newAxiom>
<newAxiom>'SLC38A2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Signal Transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201230</classIRI>
<classLabel>Immunoglobulin Heavy Constant Gamma 4</classLabel>
<newAxiom>'Immunoglobulin Heavy Constant Gamma 4' EquivalentTo 'Immunoprotein' and ('Gene_Product_Is_Element_In_Pathway' some 'IL4-Mediated Signaling Pathway') and ('Gene_Product_Has_Chemical_Classification' some 'Immunoglobulin Family Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Immunoglobulin Constant Region') and ('Gene_Product_Is_Physical_Part_Of' some 'Immunoglobulin Heavy Chain') and ('Gene_Product_Is_Physical_Part_Of' some 'Immunoglobulin') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Humoral Immunity') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Antigen Binding') and ('Gene_Product_Encoded_By_Gene' some 'IGHG4 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201226</classIRI>
<classLabel>Immunoglobulin Heavy Constant Gamma 3</classLabel>
<newAxiom>'Immunoglobulin Heavy Constant Gamma 3' EquivalentTo 'Immunoprotein' and ('Gene_Product_Is_Element_In_Pathway' some 'IL4-Mediated Signaling Pathway') and ('Gene_Product_Has_Chemical_Classification' some 'Immunoglobulin Family Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Immunoglobulin Constant Region') and ('Gene_Product_Is_Physical_Part_Of' some 'Immunoglobulin Heavy Chain') and ('Gene_Product_Is_Physical_Part_Of' some 'Immunoglobulin') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Humoral Immunity') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Antigen Binding') and ('Gene_Product_Encoded_By_Gene' some 'IGHG3 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201225</classIRI>
<classLabel>IGHG3 wt Allele</classLabel>
<newAxiom>'IGHG3 wt Allele' SubClassOf 'IGHG3 Gene'</newAxiom>
<newAxiom>'IGHG3 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'IL4-Mediated Signaling Pathway'</newAxiom>
<newAxiom>'IGHG3 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '14q32.33'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201224</classIRI>
<classLabel>IGHG3 Gene</classLabel>
<newAxiom>'IGHG3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immune Response Process'</newAxiom>
<newAxiom>'IGHG3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Humoral Immunity'</newAxiom>
<newAxiom>'IGHG3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Antigen Binding'</newAxiom>
<newAxiom>'IGHG3 Gene' SubClassOf 'Immunoprotein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201223</classIRI>
<classLabel>PD-L1 Tumor Proportion Score Greater than or Equal to 5</classLabel>
<newAxiom>'PD-L1 Tumor Proportion Score Greater than or Equal to 5' SubClassOf 'Immunohistochemical Status of PD-L1'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201229</classIRI>
<classLabel>IGHG4 wt Allele</classLabel>
<newAxiom>'IGHG4 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '14q32.33'</newAxiom>
<newAxiom>'IGHG4 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'IL4-Mediated Signaling Pathway'</newAxiom>
<newAxiom>'IGHG4 wt Allele' SubClassOf 'IGHG4 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201228</classIRI>
<classLabel>IGHG4 Gene</classLabel>
<newAxiom>'IGHG4 Gene' SubClassOf 'Immunoprotein Gene'</newAxiom>
<newAxiom>'IGHG4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immune Response Process'</newAxiom>
<newAxiom>'IGHG4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Humoral Immunity'</newAxiom>
<newAxiom>'IGHG4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Antigen Binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201227</classIRI>
<classLabel>Microcyte to Erythrocyte Ratio Measurement</classLabel>
<newAxiom>'Microcyte to Erythrocyte Ratio Measurement' SubClassOf 'Blood Cell Count Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201262</classIRI>
<classLabel>CDISC DDF Timing Attribute Terminology</classLabel>
<newAxiom>'CDISC DDF Timing Attribute Terminology' SubClassOf 'CDISC DDF Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201261</classIRI>
<classLabel>CDISC DDF Scheduled Instance Attribute Terminology</classLabel>
<newAxiom>'CDISC DDF Scheduled Instance Attribute Terminology' SubClassOf 'CDISC DDF Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201260</classIRI>
<classLabel>CDISC DDF Scheduled Decision Instance Attribute Terminology</classLabel>
<newAxiom>'CDISC DDF Scheduled Decision Instance Attribute Terminology' SubClassOf 'CDISC DDF Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201266</classIRI>
<classLabel>CDISC Protocol Biomarker Attribute Terminology</classLabel>
<newAxiom>'CDISC Protocol Biomarker Attribute Terminology' SubClassOf 'CDISC Protocol Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201265</classIRI>
<classLabel>CDISC DDF Timing Relative To From Value Set Terminology</classLabel>
<newAxiom>'CDISC DDF Timing Relative To From Value Set Terminology' SubClassOf 'CDISC DDF Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201264</classIRI>
<classLabel>CDISC DDF Timing Type Value Set Terminology</classLabel>
<newAxiom>'CDISC DDF Timing Type Value Set Terminology' SubClassOf 'CDISC DDF Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201263</classIRI>
<classLabel>DDF Timing Relative To From Attribute Terminology</classLabel>
<newAxiom>'DDF Timing Relative To From Attribute Terminology' SubClassOf 'Unused Subset Concept'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201259</classIRI>
<classLabel>CDISC DDF Schedule Timeline Attribute Terminology</classLabel>
<newAxiom>'CDISC DDF Schedule Timeline Attribute Terminology' SubClassOf 'CDISC DDF Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201258</classIRI>
<classLabel>CDISC DDF Response Code Attribute Terminology</classLabel>
<newAxiom>'CDISC DDF Response Code Attribute Terminology' SubClassOf 'CDISC DDF Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201257</classIRI>
<classLabel>CDISC DDF Biomedical Concept Surrogate Attribute Terminology</classLabel>
<newAxiom>'CDISC DDF Biomedical Concept Surrogate Attribute Terminology' SubClassOf 'CDISC DDF Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201256</classIRI>
<classLabel>CDISC DDF Biomedical Concept Property Attribute Terminology</classLabel>
<newAxiom>'CDISC DDF Biomedical Concept Property Attribute Terminology' SubClassOf 'CDISC DDF Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201251</classIRI>
<classLabel>SARS Coronavirus 2 XBB.1.16.11</classLabel>
<newAxiom>'SARS Coronavirus 2 XBB.1.16.11' SubClassOf 'SARS Coronavirus 2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201250</classIRI>
<classLabel>SARS Coronavirus 2 BA.2.86</classLabel>
<newAxiom>'SARS Coronavirus 2 BA.2.86' SubClassOf 'SARS Coronavirus 2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201255</classIRI>
<classLabel>CDISC DDF Biomedical Concept Category Attribute Terminology</classLabel>
<newAxiom>'CDISC DDF Biomedical Concept Category Attribute Terminology' SubClassOf 'CDISC DDF Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201254</classIRI>
<classLabel>CDISC DDF Biomedical Concept Attribute Terminology</classLabel>
<newAxiom>'CDISC DDF Biomedical Concept Attribute Terminology' SubClassOf 'CDISC DDF Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201253</classIRI>
<classLabel>CDISC DDF Address Attribute Terminology</classLabel>
<newAxiom>'CDISC DDF Address Attribute Terminology' SubClassOf 'CDISC DDF Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201252</classIRI>
<classLabel>Werner Syndrome Helicase Inhibitor</classLabel>
<newAxiom>'Werner Syndrome Helicase Inhibitor' SubClassOf 'Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201248</classIRI>
<classLabel>SARS Coronavirus 2 EG.6.1</classLabel>
<newAxiom>'SARS Coronavirus 2 EG.6.1' SubClassOf 'SARS Coronavirus 2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201247</classIRI>
<classLabel>FLT3 Inhibitor BMF-500</classLabel>
<newAxiom>'FLT3 Inhibitor BMF-500' SubClassOf 'FLT3 Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201246</classIRI>
<classLabel>SARS Coronavirus 2 XBB.1.5.70</classLabel>
<newAxiom>'SARS Coronavirus 2 XBB.1.5.70' SubClassOf 'SARS Coronavirus 2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201245</classIRI>
<classLabel>Bioadhesive Nanoparticles-encapsulating Avobenzone/Octocrylene Plus Diosmin/Ferulic Acid/Cytisine/Trans-resveratrol Sunscreen</classLabel>
<newAxiom>'Bioadhesive Nanoparticles-encapsulating Avobenzone/Octocrylene Plus Diosmin/Ferulic Acid/Cytisine/Trans-resveratrol Sunscreen' SubClassOf 'Sunscreen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201249</classIRI>
<classLabel>SARS Coronavirus 2 GE.1</classLabel>
<newAxiom>'SARS Coronavirus 2 GE.1' SubClassOf 'SARS Coronavirus 2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201280</classIRI>
<classLabel>Gallium Ga 68-PNT6555</classLabel>
<newAxiom>'Gallium Ga 68-PNT6555' SubClassOf 'Radioimmunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201284</classIRI>
<classLabel>Age in Days at Specimen Collection</classLabel>
<newAxiom>'Age in Days at Specimen Collection' SubClassOf 'Age-Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201283</classIRI>
<classLabel>Autologous Blood Patch Pleurodesis</classLabel>
<newAxiom>'Autologous Blood Patch Pleurodesis' SubClassOf 'Pleurodesis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201282</classIRI>
<classLabel>T-cell Engaging Bispecific Antibody</classLabel>
<newAxiom>'T-cell Engaging Bispecific Antibody' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
<newAxiom>'T-cell Engaging Bispecific Antibody' SubClassOf 'Anti-CD3 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201281</classIRI>
<classLabel>Lutetium Lu 177-PNT6555</classLabel>
<newAxiom>'Lutetium Lu 177-PNT6555' SubClassOf 'Antineoplastic Radiopharmaceutical Agent'</newAxiom>
<newAxiom>'Lutetium Lu 177-PNT6555' SubClassOf 'Radioimmunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201288</classIRI>
<classLabel>Allogeneic Anti-CD6 CAR T-regulatory Cells</classLabel>
<newAxiom>'Allogeneic Anti-CD6 CAR T-regulatory Cells' SubClassOf 'Therapeutic Allogeneic Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201287</classIRI>
<classLabel>Hemi-body Radiotherapy</classLabel>
<newAxiom>'Hemi-body Radiotherapy' SubClassOf 'Extensive Radiation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201286</classIRI>
<classLabel>Radioligand Therapy</classLabel>
<newAxiom>'Radioligand Therapy' SubClassOf 'Radiopharmaceutical Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201285</classIRI>
<classLabel>Adoptive T-cell Immunotherapy</classLabel>
<newAxiom>'Adoptive T-cell Immunotherapy' SubClassOf 'Leukocyte Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201279</classIRI>
<classLabel>IgG1</classLabel>
<newAxiom>'IgG1' SubClassOf 'IgG'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201278</classIRI>
<classLabel>IgG2</classLabel>
<newAxiom>'IgG2' SubClassOf 'IgG'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201273</classIRI>
<classLabel>SARS Coronavirus 2 XBB.1.42.2</classLabel>
<newAxiom>'SARS Coronavirus 2 XBB.1.42.2' SubClassOf 'SARS Coronavirus 2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201272</classIRI>
<classLabel>Lateral Floor of Mouth</classLabel>
<newAxiom>'Lateral Floor of Mouth' SubClassOf 'Floor of Mouth'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201271</classIRI>
<classLabel>Anterior Floor of Mouth</classLabel>
<newAxiom>'Anterior Floor of Mouth' SubClassOf 'Floor of Mouth'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201270</classIRI>
<classLabel>SARS Coronavirus 2 XBB.2.3.8</classLabel>
<newAxiom>'SARS Coronavirus 2 XBB.2.3.8' SubClassOf 'SARS Coronavirus 2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201277</classIRI>
<classLabel>IgG3</classLabel>
<newAxiom>'IgG3' SubClassOf 'IgG'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201276</classIRI>
<classLabel>Ceramide/CLA/Cholesterol Controlled-release Skin Barrier Emulsion</classLabel>
<newAxiom>'Ceramide/CLA/Cholesterol Controlled-release Skin Barrier Emulsion' SubClassOf 'Topical Preparation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201275</classIRI>
<classLabel>Anti-mesothelin CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-mesothelin CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Anti-mesothelin CAR T Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201274</classIRI>
<classLabel>Anterior Two-Thirds of Tongue</classLabel>
<newAxiom>'Anterior Two-Thirds of Tongue' SubClassOf 'Organ of Special Sense Part'</newAxiom>
<newAxiom>'Anterior Two-Thirds of Tongue' SubClassOf 'Anatomic_Structure_Is_Physical_Part_Of' some 'Tongue'</newAxiom>
<newAxiom>'Anterior Two-Thirds of Tongue' SubClassOf 'Head and Neck Part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201269</classIRI>
<classLabel>SARS Coronavirus 2 HV.1</classLabel>
<newAxiom>'SARS Coronavirus 2 HV.1' SubClassOf 'SARS Coronavirus 2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201268</classIRI>
<classLabel>SARS Coronavirus 2 FD.1.1</classLabel>
<newAxiom>'SARS Coronavirus 2 FD.1.1' SubClassOf 'SARS Coronavirus 2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201267</classIRI>
<classLabel>CDISC Protocol Biomarker Category Value Set Terminology</classLabel>
<newAxiom>'CDISC Protocol Biomarker Category Value Set Terminology' SubClassOf 'CDISC Protocol Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201291</classIRI>
<classLabel>Powder for Solution for Provocation Test</classLabel>
<newAxiom>'Powder for Solution for Provocation Test' SubClassOf 'Combined Dosage Form'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201290</classIRI>
<classLabel>Powder and Solvent for Solution for Provocation Test</classLabel>
<newAxiom>'Powder and Solvent for Solution for Provocation Test' SubClassOf 'Combined Dosage Form'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201295</classIRI>
<classLabel>Allogeneic Anti-CD7 CAR T Cells 4SCAR7U</classLabel>
<newAxiom>'Allogeneic Anti-CD7 CAR T Cells 4SCAR7U' SubClassOf 'Anti-CD7 CAR T Cells Preparation'</newAxiom>
<newAxiom>'Allogeneic Anti-CD7 CAR T Cells 4SCAR7U' SubClassOf 'Allogeneic CAR-T Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201294</classIRI>
<classLabel>Subject Noncompliance</classLabel>
<newAxiom>'Subject Noncompliance' SubClassOf 'Patient Compliance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201293</classIRI>
<classLabel>2H-labeled Acetate</classLabel>
<newAxiom>'2H-labeled Acetate' SubClassOf 'Imaging Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201292</classIRI>
<classLabel>Kinase Inhibitor TQB3912</classLabel>
<newAxiom>'Kinase Inhibitor TQB3912' SubClassOf 'Protein Kinase Inhibitor'</newAxiom>
<newAxiom>'Kinase Inhibitor TQB3912' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201299</classIRI>
<classLabel>Scheduled Instance</classLabel>
<newAxiom>'Scheduled Instance' SubClassOf 'Instance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201298</classIRI>
<classLabel>Timing Type</classLabel>
<newAxiom>'Timing Type' SubClassOf 'Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201297</classIRI>
<classLabel>Timing Relative To From Name</classLabel>
<newAxiom>'Timing Relative To From Name' SubClassOf 'Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201296</classIRI>
<classLabel>Exit</classLabel>
<newAxiom>'Exit' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201289</classIRI>
<classLabel>Anti-CD38 scFv/Anti-DOTA scFv Fusion Protein CD38-SADA</classLabel>
<newAxiom>'Anti-CD38 scFv/Anti-DOTA scFv Fusion Protein CD38-SADA' SubClassOf 'Biological Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201123</classIRI>
<classLabel>XPO1 NP_003391.1:p.E571K</classLabel>
<newAxiom>'XPO1 NP_003391.1:p.E571K' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'XPO1 NM_003400.4:c.1711GA'</newAxiom>
<newAxiom>'XPO1 NP_003391.1:p.E571K' SubClassOf 'XPO1 Protein Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201122</classIRI>
<classLabel>XPO1 Protein Variant</classLabel>
<newAxiom>'XPO1 Protein Variant' SubClassOf 'Gene Product Sequence Variation'</newAxiom>
<newAxiom>'XPO1 Protein Variant' SubClassOf 'Gene_Product_Variant_Of_Gene_Product' some 'Exportin-1'</newAxiom>
<newAxiom>'XPO1 Protein Variant' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'XPO1 Gene'</newAxiom>
<newAxiom>'XPO1 Protein Variant' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'XPO1 Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201121</classIRI>
<classLabel>XPO1 NM_003400.4:c.1711GA</classLabel>
<newAxiom>'XPO1 NM_003400.4:c.1711GA' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'XPO1 NP_003391.1:p.E571K'</newAxiom>
<newAxiom>'XPO1 NM_003400.4:c.1711GA' SubClassOf 'Activating XPO1 Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201120</classIRI>
<classLabel>Activating XPO1 Gene Mutation</classLabel>
<newAxiom>'Activating XPO1 Gene Mutation' SubClassOf 'XPO1 Gene Mutation'</newAxiom>
<newAxiom>'Activating XPO1 Gene Mutation' SubClassOf 'Gain of Function Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201141</classIRI>
<classLabel>Anti-AXL Antibody-drug Conjugate</classLabel>
<newAxiom>'Anti-AXL Antibody-drug Conjugate' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201140</classIRI>
<classLabel>Anti-KIR3DL3 Monoclonal Antibody NPX267</classLabel>
<newAxiom>'Anti-KIR3DL3 Monoclonal Antibody NPX267' SubClassOf 'Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-KIR3DL3 Monoclonal Antibody NPX267' SubClassOf 'Immune Checkpoint Inhibitor'</newAxiom>
<newAxiom>'Anti-KIR3DL3 Monoclonal Antibody NPX267' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201145</classIRI>
<classLabel>Anti-EGFR Gamma Delta T-cell Engaging Bispecific Antibody SGN-EGFRd2</classLabel>
<newAxiom>'Anti-EGFR Gamma Delta T-cell Engaging Bispecific Antibody SGN-EGFRd2' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-EGFR Gamma Delta T-cell Engaging Bispecific Antibody SGN-EGFRd2' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-EGFR Gamma Delta T-cell Engaging Bispecific Antibody SGN-EGFRd2' SubClassOf 'Anti-EGFR Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201144</classIRI>
<classLabel>Anti-CLDN18.2 CAR-T Cells AZD6422</classLabel>
<newAxiom>'Anti-CLDN18.2 CAR-T Cells AZD6422' SubClassOf 'Anti-Claudin18.2 CAR T Cells Preparation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201143</classIRI>
<classLabel>Hpk1 Inhibitor BGB-26808</classLabel>
<newAxiom>'Hpk1 Inhibitor BGB-26808' SubClassOf 'Hpk1 Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201142</classIRI>
<classLabel>Anti-PD-1/Anti-TGFbRII Bispecific Antibody INCA33890</classLabel>
<newAxiom>'Anti-PD-1/Anti-TGFbRII Bispecific Antibody INCA33890' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-PD-1/Anti-TGFbRII Bispecific Antibody INCA33890' SubClassOf 'Anti-PD1 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201138</classIRI>
<classLabel>PSA Nadir Less than 0.2 ng/mL</classLabel>
<newAxiom>'PSA Nadir Less than 0.2 ng/mL' SubClassOf 'PSA Level Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201137</classIRI>
<classLabel>PSA Decline Greater than 50 Percent</classLabel>
<newAxiom>'PSA Decline Greater than 50 Percent' SubClassOf 'PSA Level Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201136</classIRI>
<classLabel>Solid Pseudopapillary Neoplasm</classLabel>
<newAxiom>'Solid Pseudopapillary Neoplasm' EquivalentTo 'Malignant Neoplasm' and ('Disease_Has_Finding' some 'Lobulated Growth Pattern') and ('Disease_Has_Finding' some 'Pseudopapillary Pattern') and ('Disease_Has_Finding' some 'Low Grade Lesion') and ('Disease_Has_Finding' some 'Cystic Change') and ('Disease_Is_Grade' some 'Low Grade') and ('Disease_Mapped_To_Gene' some 'CTNNB1 Gene') and ('Disease_May_Have_Molecular_Abnormality' some 'CTNNB1 Gene Mutation')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201135</classIRI>
<classLabel>Goblet Cell Adenocarcinoma</classLabel>
<newAxiom>'Goblet Cell Adenocarcinoma' EquivalentTo 'Adenocarcinoma with Neuroendocrine Differentiation' and ('Disease_Has_Abnormal_Cell' some 'Signet Ring Adenocarcinoma Cell')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201139</classIRI>
<classLabel>Prostate Radiation Therapy</classLabel>
<newAxiom>'Prostate Radiation Therapy' SubClassOf 'Radiation Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201130</classIRI>
<classLabel>Cell-depleting Therapy</classLabel>
<newAxiom>'Cell-depleting Therapy' SubClassOf 'Immunosuppressive Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201133</classIRI>
<classLabel>Adenosine Axis Inhibitor</classLabel>
<newAxiom>'Adenosine Axis Inhibitor' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201132</classIRI>
<classLabel>Autologous Anti-MAGE-A1 TCR-engineered T-cells TSC-204-C0702</classLabel>
<newAxiom>'Autologous Anti-MAGE-A1 TCR-engineered T-cells TSC-204-C0702' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous Anti-MAGE-A1 TCR-engineered T-cells TSC-204-C0702' SubClassOf 'T-cell Receptor-engineered T-cells'</newAxiom>
<newAxiom>'Autologous Anti-MAGE-A1 TCR-engineered T-cells TSC-204-C0702' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201131</classIRI>
<classLabel>DNA Plasmid Vaccine ITI-1001</classLabel>
<newAxiom>'DNA Plasmid Vaccine ITI-1001' SubClassOf 'Antineoplastic Vaccine'</newAxiom>
<newAxiom>'DNA Plasmid Vaccine ITI-1001' SubClassOf 'DNA Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201127</classIRI>
<classLabel>Aleukemic Myeloid leukemia</classLabel>
<newAxiom>'Aleukemic Myeloid leukemia' EquivalentTo 'Myeloid Leukemia' and 'Aleukemic Leukemia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201126</classIRI>
<classLabel>Rectal Surgery</classLabel>
<newAxiom>'Rectal Surgery' SubClassOf 'Digestive System Surgery'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201125</classIRI>
<classLabel>Chest Radiation Therapy</classLabel>
<newAxiom>'Chest Radiation Therapy' SubClassOf 'Radiation Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201124</classIRI>
<classLabel>Cribriform Comedo-Type Adenocarcinoma</classLabel>
<newAxiom>'Cribriform Comedo-Type Adenocarcinoma' EquivalentTo 'Comedo-Type Adenocarcinoma' and ('Disease_Has_Finding' some 'Cribriform Pattern')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201129</classIRI>
<classLabel>Angiofibroma of Nose</classLabel>
<newAxiom>'Angiofibroma of Nose' EquivalentTo 'Angiofibroma' and ('Disease_Has_Primary_Anatomic_Site' some 'Nose')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201128</classIRI>
<classLabel>CDK2 Inhibitor ARTS-021</classLabel>
<newAxiom>'CDK2 Inhibitor ARTS-021' SubClassOf 'Cyclin-Dependent Kinase 2 Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201163</classIRI>
<classLabel>Ribitol-5-Phosphate Transferase FKTN</classLabel>
<newAxiom>'Ribitol-5-Phosphate Transferase FKTN' EquivalentTo 'Phosphotransferase' and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Golgi Apparatus') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Glycosylation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Signal Transduction') and ('Gene_Product_Encoded_By_Gene' some 'FKTN Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201162</classIRI>
<classLabel>FKTN wt Allele</classLabel>
<newAxiom>'FKTN wt Allele' SubClassOf 'FKTN Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201161</classIRI>
<classLabel>FKTN Gene</classLabel>
<newAxiom>'FKTN Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Glycosylation'</newAxiom>
<newAxiom>'FKTN Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Signal Transduction'</newAxiom>
<newAxiom>'FKTN Gene' SubClassOf 'Phosphotransferase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201160</classIRI>
<classLabel>FYVE, RhoGEF and PH Domain-Containing Protein 1</classLabel>
<newAxiom>'FYVE, RhoGEF and PH Domain-Containing Protein 1' EquivalentTo 'Guanine Nucleotide Exchange Factor' and ('Gene_Product_Is_Element_In_Pathway' some 'Actin Cytoskeleton Regulation Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoskeleton Filament') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'DH Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'PH Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Regulation of Cell Shape') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cytoskeletal Modeling') and ('Gene_Product_Encoded_By_Gene' some 'FGD1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201167</classIRI>
<classLabel>Ribitol 5-Phosphate Transferase FKRP</classLabel>
<newAxiom>'Ribitol 5-Phosphate Transferase FKRP' EquivalentTo 'Phosphotransferase' and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Rough Endoplasmic Reticulum') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Golgi Apparatus') and ('Gene_Product_Has_Associated_Anatomy' some 'Sarcolemma') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Glycosylation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Signal Transduction') and ('Gene_Product_Encoded_By_Gene' some 'FKRP Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201166</classIRI>
<classLabel>FKRP wt Allele</classLabel>
<newAxiom>'FKRP wt Allele' SubClassOf 'FKRP Gene'</newAxiom>
<newAxiom>'FKRP wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '19q13.32'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201165</classIRI>
<classLabel>FKRP Gene</classLabel>
<newAxiom>'FKRP Gene' SubClassOf 'Phosphotransferase Gene'</newAxiom>
<newAxiom>'FKRP Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Glycosylation'</newAxiom>
<newAxiom>'FKRP Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Signal Transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201164</classIRI>
<classLabel>Anti-CD39 Monoclonal Antibody</classLabel>
<newAxiom>'Anti-CD39 Monoclonal Antibody' SubClassOf 'Adenosine Axis Inhibitor'</newAxiom>
<newAxiom>'Anti-CD39 Monoclonal Antibody' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201159</classIRI>
<classLabel>FGD1 wt Allele</classLabel>
<newAxiom>'FGD1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some 'Xp11.22'</newAxiom>
<newAxiom>'FGD1 wt Allele' SubClassOf 'FGD1 Gene'</newAxiom>
<newAxiom>'FGD1 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Actin Cytoskeleton Regulation Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201158</classIRI>
<classLabel>FGD1 Gene</classLabel>
<newAxiom>'FGD1 Gene' SubClassOf 'Signaling Pathway Gene'</newAxiom>
<newAxiom>'FGD1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Signal Transduction'</newAxiom>
<newAxiom>'FGD1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Regulation of Cell Shape'</newAxiom>
<newAxiom>'FGD1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cytoskeletal Modeling'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201157</classIRI>
<classLabel>Serine Protease FAM111A</classLabel>
<newAxiom>'Serine Protease FAM111A' EquivalentTo 'Serine Protease' and 'DNA Repair Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoplasm') and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleoplasm') and ('Gene_Product_Has_Biochemical_Function' some 'DNA Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Replication') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Binding') and ('Gene_Product_Encoded_By_Gene' some 'FAM111A Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201152</classIRI>
<classLabel>IL-12-Fc Fusion Protein XmAb662</classLabel>
<newAxiom>'IL-12-Fc Fusion Protein XmAb662' SubClassOf 'Recombinant Interleukin'</newAxiom>
<newAxiom>'IL-12-Fc Fusion Protein XmAb662' SubClassOf 'Immunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201151</classIRI>
<classLabel>KIR3DL3 wt Allele</classLabel>
<newAxiom>'KIR3DL3 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Antigen Processing and Presentation Pathway'</newAxiom>
<newAxiom>'KIR3DL3 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Graft-Versus-Host Disease Pathway'</newAxiom>
<newAxiom>'KIR3DL3 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Natural Killer Cell-Mediated Cytotoxicity Pathway'</newAxiom>
<newAxiom>'KIR3DL3 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '19q13.42'</newAxiom>
<newAxiom>'KIR3DL3 wt Allele' SubClassOf 'KIR3DL3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201150</classIRI>
<classLabel>KIR3DL3 Gene</classLabel>
<newAxiom>'KIR3DL3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell-Mediated Cytotoxicity'</newAxiom>
<newAxiom>'KIR3DL3 Gene' SubClassOf 'Receptor Gene'</newAxiom>
<newAxiom>'KIR3DL3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immunoregulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201156</classIRI>
<classLabel>FAM111A wt Allele</classLabel>
<newAxiom>'FAM111A wt Allele' SubClassOf 'FAM111A Gene'</newAxiom>
<newAxiom>'FAM111A wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '11q12'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201155</classIRI>
<classLabel>FAM111A Gene</classLabel>
<newAxiom>'FAM111A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'DNA Replication'</newAxiom>
<newAxiom>'FAM111A Gene' SubClassOf 'DNA Repair Gene'</newAxiom>
<newAxiom>'FAM111A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'DNA Binding'</newAxiom>
<newAxiom>'FAM111A Gene' SubClassOf 'Peptidase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201154</classIRI>
<classLabel>MAT2A Inhibitor</classLabel>
<newAxiom>'MAT2A Inhibitor' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'MAT2A Inhibitor' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201153</classIRI>
<classLabel>Killer Cell Immunoglobulin-Like Receptor 3DL3</classLabel>
<newAxiom>'Killer Cell Immunoglobulin-Like Receptor 3DL3' EquivalentTo 'Receptor' and ('Gene_Product_Is_Element_In_Pathway' some 'Antigen Processing and Presentation Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Natural Killer Cell-Mediated Cytotoxicity Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Graft-Versus-Host Disease Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Natural Killer Cell') and ('Gene_Product_Has_Biochemical_Function' some 'Killer-Cell Immunoglobulin-Like Receptor') and ('Gene_Product_Has_Biochemical_Function' some 'Immunoprotein') and ('Gene_Product_Has_Biochemical_Function' some 'Cell Surface Receptor') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell-Mediated Cytotoxicity') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immunoregulation') and ('Gene_Product_Encoded_By_Gene' some 'KIR3DL3 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201149</classIRI>
<classLabel>Cholecystokinin Receptor Type A</classLabel>
<newAxiom>'Cholecystokinin Receptor Type A' EquivalentTo 'G Protein-Coupled Receptor' and ('Gene_Product_Is_Element_In_Pathway' some 'Neuroactive Ligand-Receptor Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Calcium-Mediated Signaling Pathway') and ('Gene_Product_Expressed_In_Tissue' some 'Gallbladder') and ('Gene_Product_Expressed_In_Tissue' some 'Brain') and ('Gene_Product_Expressed_In_Tissue' some 'Gastric Tissue') and ('Gene_Product_Has_Biochemical_Function' some 'Hormone Receptor') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Digestion') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cellular Secretion') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Muscle Contraction') and ('Gene_Product_Encoded_By_Gene' some 'CCKAR Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201148</classIRI>
<classLabel>CCKAR wt Allele</classLabel>
<newAxiom>'CCKAR wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Neuroactive Ligand-Receptor Signaling Pathway'</newAxiom>
<newAxiom>'CCKAR wt Allele' SubClassOf 'CCKAR Gene'</newAxiom>
<newAxiom>'CCKAR wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Calcium-Mediated Signaling Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201147</classIRI>
<classLabel>R-maxi-CHOP Regimen</classLabel>
<newAxiom>'R-maxi-CHOP Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Rituximab'</newAxiom>
<newAxiom>'R-maxi-CHOP Regimen' SubClassOf 'Regimen_Has_Accepted_Use_For_Disease' some 'Non-Hodgkin Lymphoma'</newAxiom>
<newAxiom>'R-maxi-CHOP Regimen' SubClassOf 'Regimen Used to Treat Non-Hodgkin Lymphoma'</newAxiom>
<newAxiom>'R-maxi-CHOP Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Cyclophosphamide'</newAxiom>
<newAxiom>'R-maxi-CHOP Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Vincristine Sulfate'</newAxiom>
<newAxiom>'R-maxi-CHOP Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Doxorubicin Hydrochloride'</newAxiom>
<newAxiom>'R-maxi-CHOP Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Prednisone'</newAxiom>
<newAxiom>'R-maxi-CHOP Regimen' SubClassOf 'Regimen_Has_Accepted_Use_For_Disease' some 'Mantle Cell Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201146</classIRI>
<classLabel>CCKAR Gene</classLabel>
<newAxiom>'CCKAR Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cellular Secretion'</newAxiom>
<newAxiom>'CCKAR Gene' SubClassOf 'G Protein-Coupled Receptor Gene'</newAxiom>
<newAxiom>'CCKAR Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Muscle Contraction'</newAxiom>
<newAxiom>'CCKAR Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Digestion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201181</classIRI>
<classLabel>Absolute T Lymphocyte Count</classLabel>
<newAxiom>'Absolute T Lymphocyte Count' SubClassOf 'CD3 Expressing T Cell Count'</newAxiom>
<newAxiom>'Absolute T Lymphocyte Count' SubClassOf 'T-Lymphocytes to Leukocytes Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201180</classIRI>
<classLabel>T Lymphocyte to Total Blood Cell Percent Measurement</classLabel>
<newAxiom>'T Lymphocyte to Total Blood Cell Percent Measurement' SubClassOf 'Lymphocyte to Total Cell Ratio Measurement'</newAxiom>
<newAxiom>'T Lymphocyte to Total Blood Cell Percent Measurement' SubClassOf 'CD3 Expressing T Cell Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201185</classIRI>
<classLabel>Absolute Cytotoxic T Lymphocyte Count</classLabel>
<newAxiom>'Absolute Cytotoxic T Lymphocyte Count' SubClassOf 'CD8 Expressing T Cell Count'</newAxiom>
<newAxiom>'Absolute Cytotoxic T Lymphocyte Count' SubClassOf 'Cytotoxic T-Lymphocytes to Leukocytes Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201184</classIRI>
<classLabel>Cytotoxic T Lymphocyte to Total Blood Cell Percent Measurement</classLabel>
<newAxiom>'Cytotoxic T Lymphocyte to Total Blood Cell Percent Measurement' SubClassOf 'CD8 Expressing T Cell Count'</newAxiom>
<newAxiom>'Cytotoxic T Lymphocyte to Total Blood Cell Percent Measurement' SubClassOf 'Cytotoxic T-Lymphocytes to Total Cells Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201183</classIRI>
<classLabel>Absolute Helper T Lymphocyte Count</classLabel>
<newAxiom>'Absolute Helper T Lymphocyte Count' SubClassOf 'CD4 Expressing T Cell Count'</newAxiom>
<newAxiom>'Absolute Helper T Lymphocyte Count' SubClassOf 'Helper T-Lymphocytes to Leukocytes Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201182</classIRI>
<classLabel>Helper T Lymphocyte to Total Blood Cell Percent Measurement</classLabel>
<newAxiom>'Helper T Lymphocyte to Total Blood Cell Percent Measurement' SubClassOf 'Helper T-Lymphocytes to Total Cells Ratio Measurement'</newAxiom>
<newAxiom>'Helper T Lymphocyte to Total Blood Cell Percent Measurement' SubClassOf 'CD4 Expressing T Cell Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201189</classIRI>
<classLabel>Anti-CA19-9 Antibody hu5B1/TCO Immunoconjugate</classLabel>
<newAxiom>'Anti-CA19-9 Antibody hu5B1/TCO Immunoconjugate' SubClassOf 'Immunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201188</classIRI>
<classLabel>Absolute B Lymphocyte Count</classLabel>
<newAxiom>'Absolute B Lymphocyte Count' SubClassOf 'B-Lymphocyte Count'</newAxiom>
<newAxiom>'Absolute B Lymphocyte Count' SubClassOf 'B-Lymphocyte to Leukocyte Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201187</classIRI>
<classLabel>Lead Pb 212 VMT-a-NET</classLabel>
<newAxiom>'Lead Pb 212 VMT-a-NET' SubClassOf 'Radioconjugate'</newAxiom>
<newAxiom>'Lead Pb 212 VMT-a-NET' SubClassOf 'Targeted Alpha Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201186</classIRI>
<classLabel>Absolute Activated T Lymphocyte Count</classLabel>
<newAxiom>'Absolute Activated T Lymphocyte Count' SubClassOf 'T-Lymphocyte Count'</newAxiom>
<newAxiom>'Absolute Activated T Lymphocyte Count' SubClassOf 'T-Lymphocytes to Leukocytes Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201170</classIRI>
<classLabel>Adenosine A2A Receptor Antagonist</classLabel>
<newAxiom>'Adenosine A2A Receptor Antagonist' SubClassOf 'Immunostimulant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201174</classIRI>
<classLabel>Anti-CD20 CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-CD20 CAR T Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Anti-CD20 CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201173</classIRI>
<classLabel>Anti-CD22 CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-CD22 CAR T Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Anti-CD22 CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201172</classIRI>
<classLabel>Anti-Claudin18.2 CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-Claudin18.2 CAR T Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Anti-Claudin18.2 CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201171</classIRI>
<classLabel>Adenosine A2B Receptor Antagonist</classLabel>
<newAxiom>'Adenosine A2B Receptor Antagonist' SubClassOf 'Immunostimulant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201178</classIRI>
<classLabel>Anti-PSMA CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-PSMA CAR T Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Anti-PSMA CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201177</classIRI>
<classLabel>Anti-CD7 CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-CD7 CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Anti-CD7 CAR T Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201176</classIRI>
<classLabel>Anti-CD70 CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-CD70 CAR T Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Anti-CD70 CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201175</classIRI>
<classLabel>Anti-EGFR CAR T Cells Preparation</classLabel>
<newAxiom>'Anti-EGFR CAR T Cells Preparation' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Anti-EGFR CAR T Cells Preparation' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201169</classIRI>
<classLabel>FLT3 NP_004110.2:p.F590_R595delinsL</classLabel>
<newAxiom>'FLT3 NP_004110.2:p.F590_R595delinsL' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'FLT3 NM_004119.2:c.1770_1784del15'</newAxiom>
<newAxiom>'FLT3 NP_004110.2:p.F590_R595delinsL' SubClassOf 'FLT3 Protein Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201168</classIRI>
<classLabel>FLT3 NM_004119.2:c.1770_1784del15</classLabel>
<newAxiom>'FLT3 NM_004119.2:c.1770_1784del15' SubClassOf 'Non-synonymous FLT3 Gene Mutation'</newAxiom>
<newAxiom>'FLT3 NM_004119.2:c.1770_1784del15' SubClassOf 'Gene_Mutant_Encodes_Gene_Product_Sequence_Variation' some 'FLT3 NP_004110.2:p.F590_R595delinsL'</newAxiom>
<newAxiom>'FLT3 NM_004119.2:c.1770_1784del15' SubClassOf 'Activating FLT3 Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201192</classIRI>
<classLabel>Absolute Natural Killer Cell Count</classLabel>
<newAxiom>'Absolute Natural Killer Cell Count' SubClassOf 'Natural Killer Cells to Leukocytes Ratio Measurement'</newAxiom>
<newAxiom>'Absolute Natural Killer Cell Count' SubClassOf 'Natural Killer Cell Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201191</classIRI>
<classLabel>Natural Killer Cell to Total Blood Cell Percent Measurement</classLabel>
<newAxiom>'Natural Killer Cell to Total Blood Cell Percent Measurement' SubClassOf 'Natural Killer Cell Count'</newAxiom>
<newAxiom>'Natural Killer Cell to Total Blood Cell Percent Measurement' SubClassOf 'Natural Killer Cells to Total Cells Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201190</classIRI>
<classLabel>Copper Cu 64-Tz-SarAr</classLabel>
<newAxiom>'Copper Cu 64-Tz-SarAr' SubClassOf 'Radioimmunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201196</classIRI>
<classLabel>Metastatic Pancreatic Acinar Cell Carcinoma</classLabel>
<newAxiom>'Metastatic Pancreatic Acinar Cell Carcinoma' EquivalentTo 'Pancreatic Acinar Cell Carcinoma' and 'Metastatic Pancreatic Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201195</classIRI>
<classLabel>FET Family Fusion Gene</classLabel>
<newAxiom>'FET Family Fusion Gene' SubClassOf 'Gene_Has_Abnormality' some 'FET Family Gene Translocation'</newAxiom>
<newAxiom>'FET Family Fusion Gene' SubClassOf 'Fusion Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201194</classIRI>
<classLabel>Activated T Lymphocyte to Total Blood Cell Percent Measurement</classLabel>
<newAxiom>'Activated T Lymphocyte to Total Blood Cell Percent Measurement' SubClassOf 'T-Lymphocyte Count'</newAxiom>
<newAxiom>'Activated T Lymphocyte to Total Blood Cell Percent Measurement' SubClassOf 'Lymphocyte to Total Cell Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201193</classIRI>
<classLabel>B Lymphocyte to Total Blood Cell Percent Measurement</classLabel>
<newAxiom>'B Lymphocyte to Total Blood Cell Percent Measurement' SubClassOf 'B-Lymphocyte Count'</newAxiom>
<newAxiom>'B Lymphocyte to Total Blood Cell Percent Measurement' SubClassOf 'B-Lymphocyte to Total Cells Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201199</classIRI>
<classLabel>FXN Gene</classLabel>
<newAxiom>'FXN Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Ion Transport Process'</newAxiom>
<newAxiom>'FXN Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Biosynthetic Process'</newAxiom>
<newAxiom>'FXN Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transmembrane Transport'</newAxiom>
<newAxiom>'FXN Gene' SubClassOf 'Oxidoreductase Gene'</newAxiom>
<newAxiom>'FXN Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Iron Chelation'</newAxiom>
<newAxiom>'FXN Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell Respiration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201198</classIRI>
<classLabel>Myrciaria dubia Prebiotic Supplement</classLabel>
<newAxiom>'Myrciaria dubia Prebiotic Supplement' SubClassOf 'Dietary Supplement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201197</classIRI>
<classLabel>Autologous Anti-GPC2-CAR T-cells</classLabel>
<newAxiom>'Autologous Anti-GPC2-CAR T-cells' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous Anti-GPC2-CAR T-cells' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>