<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
487
</numberChangedClasses>
<numberNewClasses>
331
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C105150</classIRI>
<classLabel>Denintuzumab Mafodotin</classLabel>
<deletedAxiom>&apos;Denintuzumab Mafodotin&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Denintuzumab Mafodotin&apos; SubClassOf &apos;Immunoconjugate&apos;</deletedAxiom>
<newAxiom>&apos;Denintuzumab Mafodotin&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198859</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28249</classIRI>
<classLabel>Scientist</classLabel>
<deletedAxiom>&apos;Scientist&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Scientist&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C53446</classIRI>
<classLabel>Physicist</classLabel>
<deletedAxiom>&apos;Physicist&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Physicist&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C130038</classIRI>
<classLabel>Myeloid Neoplasms with Germline Predisposition</classLabel>
<deletedAxiom>&apos;Myeloid Neoplasms with Germline Predisposition&apos; EquivalentTo &apos;Myeloid Neoplasm&apos; and &apos;Hereditary Malignant Neoplasm&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Germline Variation&apos;)</deletedAxiom>
<newAxiom>&apos;Myeloid Neoplasms with Germline Predisposition&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198663 and &apos;Hereditary Malignant Neoplasm&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Germline Variation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C130043</classIRI>
<classLabel>Early T Acute Lymphoblastic Leukemia</classLabel>
<deletedAxiom>&apos;Early T Acute Lymphoblastic Leukemia&apos; EquivalentTo &apos;T Acute Lymphoblastic Leukemia&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Limited Early T-Cell Differentiation&apos;)</deletedAxiom>
<newAxiom>&apos;Early T Acute Lymphoblastic Leukemia&apos; EquivalentTo &apos;T Acute Lymphoblastic Leukemia&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Limited Early T-Cell Differentiation&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;BCL11B Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Activating FLT3 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C119620</classIRI>
<classLabel>Navicixizumab</classLabel>
<newAxiom>&apos;Navicixizumab&apos; SubClassOf &apos;Anti-VEGF Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3336</classIRI>
<classLabel>Polycythemia Vera</classLabel>
<deletedAxiom>&apos;Polycythemia Vera&apos; EquivalentTo &apos;Polycythemia&apos; and &apos;Myeloproliferative Neoplasm&apos; and &apos;Erythroid Neoplasm&apos; and ((&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(9;22)(q34.1;q11.2)&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;Philadelphia Chromosome&apos;)) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Multipotent Bone Marrow Stem Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 9&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 13q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 1p&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Chronic Clinical Course&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;JAK2 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;JAK2 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Polycythemia Vera&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198555 and &apos;Polycythemia&apos; and &apos;Erythroid Neoplasm&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Multipotent Bone Marrow Stem Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 9&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 13q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 1p&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Chronic Clinical Course&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;JAK2 NP_004963.1:p.V617F&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;JAK2 Exon 12 Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3273</classIRI>
<classLabel>Neurofibromatosis Type 1</classLabel>
<deletedAxiom>&apos;Neurofibromatosis Type 1&apos; EquivalentTo &apos;RASopathy&apos; and &apos;Neurofibromatosis&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;NF1 Gene Inactivation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Cafe Au Lait Spot&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;NF1-Associated Malignant Peripheral Nerve Sheath Tumor&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Seizure Disorder&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Hydrocephalus&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Adrenal Gland Pheochromocytoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Rhabdomyosarcoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Macrocephaly&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Pilocytic Astrocytoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Optic Nerve Glioma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Neuropathy&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Duodenal Neuroendocrine Tumor G1&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ampulla of Vater Neuroendocrine Neoplasm&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Neurofibroma&apos;) and (&apos;Disease_Mapped_To_Chromosome&apos; some &apos;Human Chromosome 17&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;NF1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Neurofibromatosis Type 1&apos; EquivalentTo &apos;RASopathy&apos; and &apos;Neurofibromatosis&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;NF1 Gene Inactivation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Cafe Au Lait Spot&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;NF1-Associated Malignant Peripheral Nerve Sheath Tumor&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198680) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Seizure Disorder&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Hydrocephalus&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Adrenal Gland Pheochromocytoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Rhabdomyosarcoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Macrocephaly&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Pilocytic Astrocytoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Optic Nerve Glioma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Neuropathy&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Duodenal Neuroendocrine Tumor G1&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ampulla of Vater Neuroendocrine Neoplasm&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Neurofibroma&apos;) and (&apos;Disease_Mapped_To_Chromosome&apos; some &apos;Human Chromosome 17&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;NF1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3179</classIRI>
<classLabel>Chronic Neutrophilic Leukemia</classLabel>
<deletedAxiom>&apos;Chronic Neutrophilic Leukemia&apos; EquivalentTo &apos;Chronic Leukemia&apos; and &apos;Myeloproliferative Neoplasm&apos; and ((&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(9;22)(q34.1;q11.2)&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;Philadelphia Chromosome&apos;)) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Segmented Neutrophil&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Neutrophilia&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Hypercellular Bone Marrow&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 5 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Immature Granulocytes in Peripheral Blood Under 10 Percent&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Granulocytes Increased in Bone Marrow&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Toxic Neutrophil&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 9&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 11q ATM Gene Locus&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Chronic Clinical Course&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Plasma Cell Myeloma&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Dysplastic Granulocyte&apos;)</deletedAxiom>
<newAxiom>&apos;Chronic Neutrophilic Leukemia&apos; EquivalentTo &apos;Chronic Leukemia&apos; and &apos;Myeloproliferative Neoplasm&apos; and ((&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(9;22)(q34.1;q11.2)&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;Philadelphia Chromosome&apos;)) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Segmented Neutrophil&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Neutrophilia&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Hypercellular Bone Marrow&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 5 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Immature Granulocytes in Peripheral Blood Under 10 Percent&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Granulocytes Increased in Bone Marrow&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Toxic Neutrophil&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 9&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 11q ATM Gene Locus&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Chronic Clinical Course&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Plasma Cell Myeloma&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Dysplastic Granulocyte&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CSF3R Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;SRSF2 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CSF3R Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;SETBP1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;ASXL1 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3182</classIRI>
<classLabel>Acute Promyelocytic Leukemia with PML-RARA</classLabel>
<deletedAxiom>&apos;Acute Promyelocytic Leukemia with PML-RARA&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Recurrent Genetic Abnormalities&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Bone Marrow Stem Cell with Potential to Differentiate to Granulocytic Lineage&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Promyelocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;PML-RARA Fusion Protein Expression&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;t(15;17)(q24;q21)&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Neoplastic Promyelocytes in Bone Marrow Markedly Increased&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Faggot Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Disseminated Intravascular Coagulation&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;RARA Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;PML/RARA Fusion Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Promyelocytic Leukemia with PML-RARA&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Recurrent Genetic Abnormalities&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Bone Marrow Stem Cell with Potential to Differentiate to Granulocytic Lineage&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Promyelocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;PML-RARA Fusion Protein Expression&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;RARA Gene Rearrangement&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;t(15;17)(q24;q21)&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Neoplastic Promyelocytes in Bone Marrow Markedly Increased&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Faggot Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Disseminated Intravascular Coagulation&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;RARA Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;PML/RARA Fusion Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C183495</classIRI>
<classLabel>Juxtascleral Route of Administration</classLabel>
<deletedAxiom>&apos;Juxtascleral Route of Administration&apos; SubClassOf &apos;Ophthalmic Route of Administration&apos;</deletedAxiom>
<newAxiom>&apos;Juxtascleral Route of Administration&apos; SubClassOf &apos;Route of Administration&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C197875</classIRI>
<classLabel>Balo Concentric Sclerosis</classLabel>
<deletedAxiom>&apos;Balo Concentric Sclerosis&apos; SubClassOf &apos;Demyelinating Disorder of Central Nervous System&apos;</deletedAxiom>
<newAxiom>&apos;Balo Concentric Sclerosis&apos; SubClassOf &apos;Multiple Sclerosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158416</classIRI>
<classLabel>Blood DNA</classLabel>
<deletedAxiom>&apos;Blood DNA&apos; SubClassOf &apos;Biospecimen&apos;</deletedAxiom>
<newAxiom>&apos;Blood DNA&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198567</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3407</classIRI>
<classLabel>Essential Thrombocythemia</classLabel>
<deletedAxiom>&apos;Essential Thrombocythemia&apos; EquivalentTo &apos;Myeloproliferative Neoplasm&apos; and &apos;Megakaryocytic Neoplasm&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Multipotent Bone Marrow Stem Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Giant Platelet&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Large Atypical Platelet&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Large Megakaryocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Giant Megakaryocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Megakaryocytes Increased in Bone Marrow&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Thrombocytosis&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Chronic Clinical Course&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 13q&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hypercellular Bone Marrow&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Thrombosis&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Tear-Drop Red Blood Cell&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(9;22)(q34.1;q11.2)&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;Philadelphia Chromosome&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Bone Marrow Fibrosis&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Leukoerythroblastic Reaction&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Bone Marrow Dysplasia Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Increased Red Cell Mass&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;JAK2 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;JAK2 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Essential Thrombocythemia&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198555 and &apos;Megakaryocytic Neoplasm&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Multipotent Bone Marrow Stem Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Giant Platelet&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Large Atypical Platelet&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Large Megakaryocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Giant Megakaryocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Megakaryocytes Increased in Bone Marrow&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Thrombocytosis&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Chronic Clinical Course&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 13q&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hypercellular Bone Marrow&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Thrombosis&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Tear-Drop Red Blood Cell&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Bone Marrow Fibrosis&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Leukoerythroblastic Reaction&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Bone Marrow Dysplasia Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Increased Red Cell Mass&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;MPL Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CALR Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;JAK2 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C197926</classIRI>
<classLabel>Lymphocytic Variant Hypereosinophilic Syndrome</classLabel>
<deletedAxiom>&apos;Lymphocytic Variant Hypereosinophilic Syndrome&apos; SubClassOf &apos;Hypereosinophilic Syndrome&apos;</deletedAxiom>
<newAxiom>&apos;Lymphocytic Variant Hypereosinophilic Syndrome&apos; EquivalentTo &apos;Hypereosinophilic Syndrome&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gene Rearrangement&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C197965</classIRI>
<classLabel>Schizotypal Disorder</classLabel>
<deletedAxiom>&apos;Schizotypal Disorder&apos; SubClassOf &apos;Schizophrenia and Other Psychotic Disorders&apos;</deletedAxiom>
<newAxiom>&apos;Schizotypal Disorder&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C197982</classIRI>
<classLabel>Swyer-James-MacLeod Syndrome</classLabel>
<deletedAxiom>&apos;Swyer-James-MacLeod Syndrome&apos; SubClassOf &apos;Syndrome&apos;</deletedAxiom>
<newAxiom>&apos;Swyer-James-MacLeod Syndrome&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48215</classIRI>
<classLabel>Poly [ADP-Ribose] Polymerase 1</classLabel>
<deletedAxiom>&apos;Poly [ADP-Ribose] Polymerase 1&apos; EquivalentTo &apos;PARP1 Gene Product&apos; and &apos;Glycosyltransferase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;AIF Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Caspase Cascade Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;DR3 and DR4/5 Mediated Apoptosis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Base Excision Repair Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Caspase Cascade in Apoptosis&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;BRCT Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Poly-ADP-Ribosylation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcription Initiation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Base Excision Repair&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;PARP1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Poly [ADP-Ribose] Polymerase 1&apos; EquivalentTo &apos;PARP1 Gene Product&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;AIF Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Caspase Cascade Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;DR3 and DR4/5 Mediated Apoptosis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Base Excision Repair Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Caspase Cascade in Apoptosis&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;BRCT Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Poly-ADP-Ribosylation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcription Initiation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Base Excision Repair&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;PARP1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124883</classIRI>
<classLabel>Complement Factor H-Related Protein 1</classLabel>
<deletedAxiom>&apos;Complement Factor H-Related Protein 1&apos; SubClassOf &apos;Complement Component Protein&apos;</deletedAxiom>
<deletedAxiom>&apos;Complement Factor H-Related Protein 1&apos; SubClassOf &apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Sushi Domain&apos;</deletedAxiom>
<deletedAxiom>&apos;Complement Factor H-Related Protein 1&apos; SubClassOf &apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Blood&apos;</deletedAxiom>
<deletedAxiom>&apos;Complement Factor H-Related Protein 1&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CFHR1 Gene&apos;</deletedAxiom>
<deletedAxiom>&apos;Complement Factor H-Related Protein 1&apos; SubClassOf &apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Extracellular Space&apos;</deletedAxiom>
<newAxiom>&apos;Complement Factor H-Related Protein 1&apos; EquivalentTo &apos;Complement Component Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Complement and Coagulation Cascade&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Extracellular Space&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Blood&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Sushi Domain&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CFHR1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124882</classIRI>
<classLabel>CFHR1 wt Allele</classLabel>
<deletedAxiom>&apos;CFHR1 wt Allele&apos; SubClassOf &apos;Gene_In_Chromosomal_Location&apos; some &apos;1q32&apos;</deletedAxiom>
<deletedAxiom>&apos;CFHR1 wt Allele&apos; SubClassOf &apos;CFHR1 Gene&apos;</deletedAxiom>
<newAxiom>&apos;CFHR1 wt Allele&apos; EquivalentTo &apos;CFHR1 Gene&apos; and (&apos;Gene_Is_Element_In_Pathway&apos; some &apos;Complement and Coagulation Cascade&apos;) and (&apos;Gene_In_Chromosomal_Location&apos; some &apos;1q32&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C183133</classIRI>
<classLabel>CD19x22 Bicistronic CAR T-cells</classLabel>
<newAxiom>&apos;CD19x22 Bicistronic CAR T-cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3815</classIRI>
<classLabel>Malignant Ascites</classLabel>
<newAxiom>&apos;Malignant Ascites&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198611</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125549</classIRI>
<classLabel>Loncastuximab Tesirine</classLabel>
<deletedAxiom>&apos;Loncastuximab Tesirine&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Loncastuximab Tesirine&apos; SubClassOf &apos;Immunoconjugate&apos;</deletedAxiom>
<newAxiom>&apos;Loncastuximab Tesirine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198859</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150393</classIRI>
<classLabel>Indoximod Prodrug NLG802</classLabel>
<deletedAxiom>&apos;Indoximod Prodrug NLG802&apos; SubClassOf &apos;Antineoplastic Immunomodulating Agent&apos;</deletedAxiom>
<newAxiom>&apos;Indoximod Prodrug NLG802&apos; SubClassOf &apos;IDO1 Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198469</classIRI>
<classLabel>Administration Method of Administration</classLabel>
<deletedAxiom>&apos;Administration Method of Administration&apos; SubClassOf &apos;Agent Administration&apos;</deletedAxiom>
<newAxiom>&apos;Administration Method of Administration&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150407</classIRI>
<classLabel>Body Cavity Primary Effusion Lymphoma</classLabel>
<deletedAxiom>&apos;Body Cavity Primary Effusion Lymphoma&apos; EquivalentTo &apos;Primary Effusion Lymphoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Body Cavity&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Effusion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pericardial Effusion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pleural Effusion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Peritoneal Effusion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Tumor Mass&apos;)</deletedAxiom>
<newAxiom>&apos;Body Cavity Primary Effusion Lymphoma&apos; EquivalentTo &apos;Primary Effusion Lymphoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Body Cavity&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Effusion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Ascites&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pericardial Effusion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pleural Effusion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Tumor Mass&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198411</classIRI>
<classLabel>Allogeneic Rituximab Conjugated Gamma Delta T-cells ACE1831</classLabel>
<deletedAxiom>&apos;Allogeneic Rituximab Conjugated Gamma Delta T-cells ACE1831&apos; SubClassOf &apos;CD20-targeting Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34402</classIRI>
<classLabel>Peritoneal Effusion</classLabel>
<deletedAxiom>&apos;Peritoneal Effusion&apos; SubClassOf &apos;Effusion&apos;</deletedAxiom>
<newAxiom>&apos;Peritoneal Effusion&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125192</classIRI>
<classLabel>Lisocabtagene Maraleucel</classLabel>
<deletedAxiom>&apos;Lisocabtagene Maraleucel&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Lisocabtagene Maraleucel&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34739</classIRI>
<classLabel>Jacksonian Seizure</classLabel>
<deletedAxiom>&apos;Jacksonian Seizure&apos; SubClassOf &apos;Seizure&apos;</deletedAxiom>
<newAxiom>&apos;Jacksonian Seizure&apos; SubClassOf &apos;Partial Motor Seizure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20192</classIRI>
<classLabel>Miscellaneous Occupation</classLabel>
<deletedAxiom>&apos;Miscellaneous Occupation&apos; SubClassOf &apos;Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Miscellaneous Occupation&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C93177</classIRI>
<classLabel>Notary Public</classLabel>
<deletedAxiom>&apos;Notary Public&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Notary Public&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C93174</classIRI>
<classLabel>Acupuncturist</classLabel>
<deletedAxiom>&apos;Acupuncturist&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Acupuncturist&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C93184</classIRI>
<classLabel>Aromatherapist</classLabel>
<deletedAxiom>&apos;Aromatherapist&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Aromatherapist&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C93186</classIRI>
<classLabel>Embalmer</classLabel>
<deletedAxiom>&apos;Embalmer&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Embalmer&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C93222</classIRI>
<classLabel>Child-life Worker</classLabel>
<deletedAxiom>&apos;Child-life Worker&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Child-life Worker&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34920</classIRI>
<classLabel>Chronic Peritoneal Effusion</classLabel>
<deletedAxiom>&apos;Chronic Peritoneal Effusion&apos; SubClassOf &apos;Peritoneal Effusion&apos;</deletedAxiom>
<newAxiom>&apos;Chronic Peritoneal Effusion&apos; SubClassOf &apos;Ascites&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20375</classIRI>
<classLabel>MCM5 Gene</classLabel>
<newAxiom>&apos;MCM5 Gene&apos; SubClassOf &apos;Helicase Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68608</classIRI>
<classLabel>Vendor</classLabel>
<deletedAxiom>&apos;Vendor&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Vendor&apos; SubClassOf &apos;Sales and Related Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178588</classIRI>
<classLabel>Autologous Anti-CD19 CAR-T Cells GC019F</classLabel>
<deletedAxiom>&apos;Autologous Anti-CD19 CAR-T Cells GC019F&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Anti-CD19 CAR-T Cells GC019F&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54067</classIRI>
<classLabel>Health Professional</classLabel>
<deletedAxiom>&apos;Health Professional&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Health Professional&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68730</classIRI>
<classLabel>IKZF1 Gene</classLabel>
<newAxiom>&apos;IKZF1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198685</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C105562</classIRI>
<classLabel>tRNA (Cytosine(38)-C(5))-Methyltransferase</classLabel>
<deletedAxiom>&apos;tRNA (Cytosine(38)-C(5))-Methyltransferase&apos; SubClassOf &apos;Translation Process Protein&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (Cytosine(38)-C(5))-Methyltransferase&apos; SubClassOf &apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;tRNA Methyltransferase&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (Cytosine(38)-C(5))-Methyltransferase&apos; SubClassOf &apos;Methyltransferase&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (Cytosine(38)-C(5))-Methyltransferase&apos; SubClassOf &apos;tRNA Methyltransferase&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20809</classIRI>
<classLabel>RAD54L Gene</classLabel>
<newAxiom>&apos;RAD54L Gene&apos; SubClassOf &apos;Helicase Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178424</classIRI>
<classLabel>Allogeneic CD20 CAR-grafted Gamma Delta T-cells ADI-001</classLabel>
<deletedAxiom>&apos;Allogeneic CD20 CAR-grafted Gamma Delta T-cells ADI-001&apos; SubClassOf &apos;CD20-targeting Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178448</classIRI>
<classLabel>Emfizatamab</classLabel>
<deletedAxiom>&apos;Emfizatamab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Emfizatamab&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</newAxiom>
<newAxiom>&apos;Emfizatamab&apos; SubClassOf &apos;Anti-CD137 Monoclonal Antibody&apos;</newAxiom>
<newAxiom>&apos;Emfizatamab&apos; SubClassOf &apos;Anti-PD-L1 Monoclonal Antibody&apos;</newAxiom>
<newAxiom>&apos;Emfizatamab&apos; SubClassOf &apos;Anti-CD19 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178452</classIRI>
<classLabel>Autologous Anti-CD19/CD20 CAR-T Cells C-CAR039</classLabel>
<newAxiom>&apos;Autologous Anti-CD19/CD20 CAR-T Cells C-CAR039&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29684</classIRI>
<classLabel>General Transcription Factor 3C Polypeptide 4</classLabel>
<deletedAxiom>&apos;General Transcription Factor 3C Polypeptide 4&apos; EquivalentTo &apos;Basal Transcription Factor&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;RNA Polymerase III Transcription Pathway&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcription&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;GTF3C4 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;General Transcription Factor 3C Polypeptide 4&apos; EquivalentTo &apos;Basal Transcription Factor&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;RNA Polymerase III Transcription Pathway&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Acyltransferase&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcription&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;GTF3C4 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88301</classIRI>
<classLabel>Ang2/VEGF-Binding Peptides-Antibody Fusion Protein CVX-241</classLabel>
<newAxiom>&apos;Ang2/VEGF-Binding Peptides-Antibody Fusion Protein CVX-241&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198860</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143156</classIRI>
<classLabel>Anti-CD19-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocytes</classLabel>
<newAxiom>&apos;Anti-CD19-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocytes&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157396</classIRI>
<classLabel>Carboplatin/Paclitaxel/Pembrolizumab Regimen</classLabel>
<newAxiom>&apos;Carboplatin/Paclitaxel/Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Breast Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123831</classIRI>
<classLabel>Cabiralizumab</classLabel>
<deletedAxiom>&apos;Cabiralizumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Cabiralizumab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Cabiralizumab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198645</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2496</classIRI>
<classLabel>Anti-VEGF Monoclonal Antibody</classLabel>
<deletedAxiom>&apos;Anti-VEGF Monoclonal Antibody&apos; SubClassOf &apos;Targeted Therapy Agent&apos;</deletedAxiom>
<newAxiom>&apos;Anti-VEGF Monoclonal Antibody&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198860</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2330</classIRI>
<classLabel>Anti-CD19 Immunotoxins</classLabel>
<newAxiom>&apos;Anti-CD19 Immunotoxins&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198634</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157090</classIRI>
<classLabel>Autologous CD4+/CD8+ 4-1BB-CD3zeta-EGFR806-CAR-EGFRt/4-1BB-CD3zeta-CD19-CAR-HER2tG-expressing CARs T Cells</classLabel>
<deletedAxiom>&apos;Autologous CD4+/CD8+ 4-1BB-CD3zeta-EGFR806-CAR-EGFRt/4-1BB-CD3zeta-CD19-CAR-HER2tG-expressing CARs T Cells&apos; SubClassOf &apos;T-cell Receptor-engineered T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous CD4+/CD8+ 4-1BB-CD3zeta-EGFR806-CAR-EGFRt/4-1BB-CD3zeta-CD19-CAR-HER2tG-expressing CARs T Cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</newAxiom>
<newAxiom>&apos;Autologous CD4+/CD8+ 4-1BB-CD3zeta-EGFR806-CAR-EGFRt/4-1BB-CD3zeta-CD19-CAR-HER2tG-expressing CARs T Cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2862</classIRI>
<classLabel>Primary Myelofibrosis</classLabel>
<deletedAxiom>&apos;Primary Myelofibrosis&apos; EquivalentTo &apos;Myelofibrosis&apos; and &apos;Myeloproliferative Neoplasm&apos; and ((&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(9;22)(q34.1;q11.2)&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;Philadelphia Chromosome&apos;)) and (&apos;Disease_Has_Finding&apos; some &apos;Megakaryocytes Increased in Bone Marrow&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 10 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Granulocytes Increased in Bone Marrow&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 13q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Partial Trisomy 1q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 7&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Chronic Clinical Course&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;JAK2 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;JAK2 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Myelofibrosis&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198555 and &apos;Myelofibrosis&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Megakaryocytes Increased in Bone Marrow&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 10 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Granulocytes Increased in Bone Marrow&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 13q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Partial Trisomy 1q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 7&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Chronic Clinical Course&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;MPL Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CALR Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;JAK2 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2885</classIRI>
<classLabel>Ascites</classLabel>
<deletedAxiom>&apos;Ascites&apos; SubClassOf &apos;Peritoneal Disorder&apos;</deletedAxiom>
<newAxiom>&apos;Ascites&apos; SubClassOf &apos;Effusion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35050</classIRI>
<classLabel>Surgical Wound Infection</classLabel>
<deletedAxiom>&apos;Surgical Wound Infection&apos; SubClassOf &apos;Wound Infection&apos;</deletedAxiom>
<newAxiom>&apos;Surgical Wound Infection&apos; SubClassOf &apos;Posttraumatic Wound Infection&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137819</classIRI>
<classLabel>Allogeneic CD19-specific Universal CAR19-expressing T-lymphocytes</classLabel>
<deletedAxiom>&apos;Allogeneic CD19-specific Universal CAR19-expressing T-lymphocytes&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Allogeneic CD19-specific Universal CAR19-expressing T-lymphocytes&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2682</classIRI>
<classLabel>Ziv-Aflibercept</classLabel>
<deletedAxiom>&apos;Ziv-Aflibercept&apos; SubClassOf &apos;VEGFR-targeting Agent&apos;</deletedAxiom>
<newAxiom>&apos;Ziv-Aflibercept&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198860</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2523</classIRI>
<classLabel>Monoclonal Antibody CD19</classLabel>
<deletedAxiom>&apos;Monoclonal Antibody CD19&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Monoclonal Antibody CD19&apos; SubClassOf &apos;Anti-CD19 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162872</classIRI>
<classLabel>Anti-VEGF/TGF-beta 1 Fusion Protein HB-002T</classLabel>
<newAxiom>&apos;Anti-VEGF/TGF-beta 1 Fusion Protein HB-002T&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198860</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C163995</classIRI>
<classLabel>Total RNA</classLabel>
<deletedAxiom>&apos;Total RNA&apos; SubClassOf &apos;Biospecimen&apos;</deletedAxiom>
<newAxiom>&apos;Total RNA&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198568</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C94423</classIRI>
<classLabel>Clergy</classLabel>
<deletedAxiom>&apos;Clergy&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Clergy&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21543</classIRI>
<classLabel>DNA Repair and Recombination Protein RAD54-Like</classLabel>
<deletedAxiom>&apos;DNA Repair and Recombination Protein RAD54-Like&apos; EquivalentTo &apos;DNA Repair Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Homologous Recombination Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Non-Hodgkin Lymphoma&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Colon Adenocarcinoma&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;DNA Binding Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Homologous Recombination&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Recombination Repair&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RAD54L Gene&apos;)</deletedAxiom>
<newAxiom>&apos;DNA Repair and Recombination Protein RAD54-Like&apos; EquivalentTo &apos;DNA Helicase&apos; and &apos;DNA Repair Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Homologous Recombination Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Non-Hodgkin Lymphoma&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Colon Adenocarcinoma&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;DNA Binding Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Homologous Recombination&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Recombination Repair&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RAD54L Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138040</classIRI>
<classLabel>Lapatinib/Trastuzumab Regimen</classLabel>
<newAxiom>&apos;Lapatinib/Trastuzumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Bone Cancer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138041</classIRI>
<classLabel>Capecitabine/Lapatinib Regimen</classLabel>
<newAxiom>&apos;Capecitabine/Lapatinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Colorectal Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138034</classIRI>
<classLabel>Cyclophosphamide/Docetaxel/Trastuzumab Regimen</classLabel>
<newAxiom>&apos;Cyclophosphamide/Docetaxel/Trastuzumab Regimen&apos; SubClassOf &apos;Chemotherapy_Regimen_Has_Component&apos; some &apos;Cyclophosphamide&apos;</newAxiom>
<newAxiom>&apos;Cyclophosphamide/Docetaxel/Trastuzumab Regimen&apos; SubClassOf &apos;Chemotherapy_Regimen_Has_Component&apos; some &apos;Trastuzumab&apos;</newAxiom>
<newAxiom>&apos;Cyclophosphamide/Docetaxel/Trastuzumab Regimen&apos; SubClassOf &apos;Chemotherapy_Regimen_Has_Component&apos; some &apos;Docetaxel&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177741</classIRI>
<classLabel>CD3-activating CD19 Bi-specific Antibody A-319</classLabel>
<deletedAxiom>&apos;CD3-activating CD19 Bi-specific Antibody A-319&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;CD3-activating CD19 Bi-specific Antibody A-319&apos; SubClassOf &apos;Anti-CD19 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138107</classIRI>
<classLabel>Autologous Genetically-modified MAGE-A4 C1032 T Cells</classLabel>
<deletedAxiom>&apos;Autologous Genetically-modified MAGE-A4 C1032 T Cells&apos; SubClassOf &apos;T-cell Receptor-engineered T-cells&apos;</deletedAxiom>
<deletedAxiom>&apos;Autologous Genetically-modified MAGE-A4 C1032 T Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Autologous Genetically-modified MAGE-A4 C1032 T Cells&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Genetically-modified MAGE-A4 C1032 T Cells&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177458</classIRI>
<classLabel>Axl/Mer/CSF1R Inhibitor Q702</classLabel>
<newAxiom>&apos;Axl/Mer/CSF1R Inhibitor Q702&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198646</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80245</classIRI>
<classLabel>Artist</classLabel>
<deletedAxiom>&apos;Artist&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Artist&apos; SubClassOf &apos;Arts, Design, Entertainment, Sports and Media Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80291</classIRI>
<classLabel>High Grade B-Cell Lymphoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;High Grade B-Cell Lymphoma, Not Otherwise Specified&apos; EquivalentTo &apos;High Grade B-Cell Lymphoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Morphologic Overlap&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;MYC Gene Rearrangement&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCL2 Gene Rearrangement&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCL6 Gene Rearrangement&apos;)</deletedAxiom>
<newAxiom>&apos;High Grade B-Cell Lymphoma, Not Otherwise Specified&apos; EquivalentTo &apos;High Grade B-Cell Lymphoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Morphologic Overlap&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;MYC Gene Rearrangement&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCL2 Gene Rearrangement&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCL6 Gene Rearrangement&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80280</classIRI>
<classLabel>Diffuse Large B-Cell Lymphoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Diffuse Large B-Cell Lymphoma, Not Otherwise Specified&apos; EquivalentTo &apos;Diffuse Large B-Cell Lymphoma&apos; and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Thymus Gland&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Vascular System&apos;) and (&apos;Disease_Excludes_Normal_Cell_Origin&apos; some &apos;Thymic B-Lymphocyte&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Plasmablastic Immunoblast&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;ALK Kinase Overexpression&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Histiocytosis&apos;)</deletedAxiom>
<newAxiom>&apos;Diffuse Large B-Cell Lymphoma, Not Otherwise Specified&apos; EquivalentTo &apos;Diffuse Large B-Cell Lymphoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Thymus Gland&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Vascular System&apos;) and (&apos;Disease_Excludes_Normal_Cell_Origin&apos; some &apos;Thymic B-Lymphocyte&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Plasmablastic Immunoblast&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;ALK Kinase Overexpression&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Histiocytosis&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80308</classIRI>
<classLabel>Splenic B-Cell Lymphoma/Leukemia, Unclassifiable</classLabel>
<deletedAxiom>&apos;Splenic B-Cell Lymphoma/Leukemia, Unclassifiable&apos; EquivalentTo &apos;B-Cell Malignant Neoplasm&apos; and &apos;Mature B-Cell Neoplasm&apos; and &apos;Malignant Splenic Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Spleen&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Small B-Lymphocyte&apos;)</deletedAxiom>
<newAxiom>&apos;Splenic B-Cell Lymphoma/Leukemia, Unclassifiable&apos; EquivalentTo &apos;B-Cell Malignant Neoplasm&apos; and &apos;Mature B-Cell Neoplasm&apos; and &apos;Malignant Splenic Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Spleen&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Small B-Lymphocyte&apos;) and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198590)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80326</classIRI>
<classLabel>B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified&apos; EquivalentTo &apos;B Lymphoblastic Leukemia/Lymphoma&apos; and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 12p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 6q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 9p&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;Chromosomal Translocation&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Recurrent Genetic Abnormalities Present&apos;)</deletedAxiom>
<newAxiom>&apos;B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified&apos; EquivalentTo &apos;B Lymphoblastic Leukemia/Lymphoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 12p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 6q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 9p&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;Chromosomal Translocation&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Recurrent Genetic Abnormalities Present&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118947</classIRI>
<classLabel>RNA Electroporated CD19CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocytes</classLabel>
<deletedAxiom>&apos;RNA Electroporated CD19CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocytes&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;RNA Electroporated CD19CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocytes&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104006</classIRI>
<classLabel>Anti-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocyte Cells</classLabel>
<deletedAxiom>&apos;Anti-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocyte Cells&apos; SubClassOf &apos;CD20-targeting Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104101</classIRI>
<classLabel>PARP1 Gene Product</classLabel>
<newAxiom>&apos;PARP1 Gene Product&apos; SubClassOf &apos;Glycosyltransferase&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41201</classIRI>
<classLabel>Study Monitor</classLabel>
<deletedAxiom>&apos;Study Monitor&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Study Monitor&apos; SubClassOf &apos;Study Personnel&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16285</classIRI>
<classLabel>Amyloid Beta A4 Protein</classLabel>
<deletedAxiom>&apos;Amyloid Beta A4 Protein&apos; EquivalentTo &apos;Receptor&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Alzheimer&apos;s Disease Pathway KEGG&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Amyloid Beta-Peptide Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Alzheimer&apos;s Disease Pathway BioCarta&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Platelet Amyloid Precursor Protein Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Glypican 1 Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Glycoprotein&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Extracellular Space&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Alzheimer&apos;s Disease&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Motility&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Apoptosis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Oxidative Stress&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Receptor Signaling&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Regulation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Adhesion Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;APP Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Amyloid Beta A4 Protein&apos; EquivalentTo &apos;Enzyme Inhibitor Protein&apos; and &apos;Receptor&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Alzheimer&apos;s Disease Pathway KEGG&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Amyloid Beta-Peptide Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Alzheimer&apos;s Disease Pathway BioCarta&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Platelet Amyloid Precursor Protein Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Glypican 1 Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Glycoprotein&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Extracellular Space&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Alzheimer&apos;s Disease&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Motility&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Apoptosis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Oxidative Stress&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Regulation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Metal Ion Binding&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell Adhesion Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;APP Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16223</classIRI>
<classLabel>DNA Library</classLabel>
<deletedAxiom>&apos;DNA Library&apos; SubClassOf &apos;Biospecimen&apos;</deletedAxiom>
<newAxiom>&apos;DNA Library&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198567</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132681</classIRI>
<classLabel>Anti-CD40/Anti-TAA Bispecific Monoclonal Antibody ABBV-428</classLabel>
<newAxiom>&apos;Anti-CD40/Anti-TAA Bispecific Monoclonal Antibody ABBV-428&apos; SubClassOf &apos;Anti-CD40 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132331</classIRI>
<classLabel>Human Cytomegalovirus Envelope Glycoprotein B</classLabel>
<deletedAxiom>&apos;Human Cytomegalovirus Envelope Glycoprotein B&apos; SubClassOf &apos;Viral Protein&apos;</deletedAxiom>
<newAxiom>&apos;Human Cytomegalovirus Envelope Glycoprotein B&apos; SubClassOf &apos;ENV Protein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132101</classIRI>
<classLabel>Acute Myeloid Leukemia with t(10;11)(p12;q23); MLLT10-MLL</classLabel>
<deletedAxiom>&apos;Acute Myeloid Leukemia with t(10;11)(p12;q23); MLLT10-MLL&apos; EquivalentTo &apos;Acute Myeloid Leukemia with MLL Rearrangement&apos; and &apos;Childhood Acute Myeloid Leukemia&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;KMT2A-AF10 Fusion Protein Expression&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;t(10;11)(p12;q23)&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Unfavorable Clinical Outcome&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MLL/MLLT10 Fusion Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Myeloid Leukemia with t(10;11)(p12;q23); MLLT10-MLL&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Variant MLL Translocations&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;KMT2A-AF10 Fusion Protein Expression&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;t(10;11)(p12;q23)&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Unfavorable Clinical Outcome&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MLL/MLLT10 Fusion Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132105</classIRI>
<classLabel>Acute Myeloid Leukemia with t(6;11)(q27;q23); MLLT4-MLL</classLabel>
<deletedAxiom>&apos;Acute Myeloid Leukemia with t(6;11)(q27;q23); MLLT4-MLL&apos; EquivalentTo &apos;Acute Myeloid Leukemia with MLL Rearrangement&apos; and &apos;Childhood Acute Myeloid Leukemia&apos; and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;t(6;11)(q27;q23)&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Unfavorable Clinical Outcome&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MLL/MLLT4 Fusion Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Myeloid Leukemia with t(6;11)(q27;q23); MLLT4-MLL&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Variant MLL Translocations&apos; and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;t(6;11)(q27;q23)&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Unfavorable Clinical Outcome&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MLL/MLLT4 Fusion Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107242</classIRI>
<classLabel>CD19CAR-CD28zeta-4-1BB-expressing Allogeneic T Lymphocytes</classLabel>
<deletedAxiom>&apos;CD19CAR-CD28zeta-4-1BB-expressing Allogeneic T Lymphocytes&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;CD19CAR-CD28zeta-4-1BB-expressing Allogeneic T Lymphocytes&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C146814</classIRI>
<classLabel>Capillary Sequencing</classLabel>
<deletedAxiom>&apos;Capillary Sequencing&apos; SubClassOf &apos;Nucleic Acid Sequencing&apos;</deletedAxiom>
<newAxiom>&apos;Capillary Sequencing&apos; SubClassOf &apos;DNA Sequencing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75560</classIRI>
<classLabel>Homemaker</classLabel>
<deletedAxiom>&apos;Homemaker&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Homemaker&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75561</classIRI>
<classLabel>Student</classLabel>
<deletedAxiom>&apos;Student&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Student&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75554</classIRI>
<classLabel>Skilled Worker</classLabel>
<deletedAxiom>&apos;Skilled Worker&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Skilled Worker&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75556</classIRI>
<classLabel>Laborer</classLabel>
<deletedAxiom>&apos;Laborer&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Laborer&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75558</classIRI>
<classLabel>Professional Occupation</classLabel>
<deletedAxiom>&apos;Professional Occupation&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Professional Occupation&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75553</classIRI>
<classLabel>Salesperson</classLabel>
<deletedAxiom>&apos;Salesperson&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Salesperson&apos; SubClassOf &apos;Sales and Related Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75552</classIRI>
<classLabel>Clerk</classLabel>
<deletedAxiom>&apos;Clerk&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Clerk&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185865</classIRI>
<classLabel>Anti-DLL4/Anti-VEGF-A Bispecific Antibody CTX-009</classLabel>
<newAxiom>&apos;Anti-DLL4/Anti-VEGF-A Bispecific Antibody CTX-009&apos; SubClassOf &apos;Anti-VEGF Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36055</classIRI>
<classLabel>Acute Myeloid Leukemia with a Variant RARA Translocation</classLabel>
<deletedAxiom>&apos;Acute Myeloid Leukemia with a Variant RARA Translocation&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Recurrent Genetic Abnormalities&apos; and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;Chromosomal Rearrangement&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;PML-RARA Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(15;17)(q24;q21)&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;RARA Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Myeloid Leukemia with a Variant RARA Translocation&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Recurrent Genetic Abnormalities&apos; and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;RARA Gene Rearrangement&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;Chromosomal Rearrangement&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;PML-RARA Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(15;17)(q24;q21)&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;RARA Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171093</classIRI>
<classLabel>Autologous Bispecific CD19/CD22-targeted CAR-T Cells GC022</classLabel>
<newAxiom>&apos;Autologous Bispecific CD19/CD22-targeted CAR-T Cells GC022&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36319</classIRI>
<classLabel>t(8;14)(q24;q32)</classLabel>
<deletedAxiom>&apos;t(8;14)(q24;q32)&apos; SubClassOf &apos;MYC Gene Rearrangement&apos;</deletedAxiom>
<deletedAxiom>&apos;t(8;14)(q24;q32)&apos; SubClassOf &apos;Chromosomal Translocation&apos;</deletedAxiom>
<newAxiom>&apos;t(8;14)(q24;q32)&apos; SubClassOf &apos;C-Myc Translocation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112889</classIRI>
<classLabel>Anti-CD19 Monoclonal Antibody</classLabel>
<newAxiom>&apos;Anti-CD19 Monoclonal Antibody&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198634</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171176</classIRI>
<classLabel>Nucleic Acid Aliquot</classLabel>
<deletedAxiom>&apos;Nucleic Acid Aliquot&apos; SubClassOf &apos;Biospecimen&apos;</deletedAxiom>
<newAxiom>&apos;Nucleic Acid Aliquot&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198566</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172063</classIRI>
<classLabel>Autologous Anti-CD20 CAR Transduced CD4/CD8 Enriched T-cells MB-CART20.1</classLabel>
<deletedAxiom>&apos;Autologous Anti-CD20 CAR Transduced CD4/CD8 Enriched T-cells MB-CART20.1&apos; SubClassOf &apos;CD20-targeting Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172057</classIRI>
<classLabel>Autologous Anti-CD19/CD20 Bispecific Nanobody-based CAR-T cells</classLabel>
<newAxiom>&apos;Autologous Anti-CD19/CD20 Bispecific Nanobody-based CAR-T cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172010</classIRI>
<classLabel>More Complex Surgery</classLabel>
<deletedAxiom>&apos;More Complex Surgery&apos; SubClassOf &apos;HIV Drug Resistance Program&apos;</deletedAxiom>
<newAxiom>&apos;More Complex Surgery&apos; SubClassOf &apos;Surgical Procedure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186349</classIRI>
<classLabel>Supratentorial Ependymoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Supratentorial Ependymoma, Not Otherwise Specified&apos; EquivalentTo &apos;Supratentorial Ependymoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;YAP1 and ZFTA Gene Rearrangements Status Unknown&apos;)</deletedAxiom>
<newAxiom>&apos;Supratentorial Ependymoma, Not Otherwise Specified&apos; EquivalentTo &apos;Supratentorial Ependymoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;YAP1 and ZFTA Gene Rearrangements Status Unknown&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186448</classIRI>
<classLabel>Posterior Fossa Ependymoma, Not Elsewhere Classified</classLabel>
<deletedAxiom>&apos;Posterior Fossa Ependymoma, Not Elsewhere Classified&apos; EquivalentTo &apos;Posterior Fossa Ependymoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Absence of Distinct DNA Methylation Profiling Molecular Group&apos;)</deletedAxiom>
<newAxiom>&apos;Posterior Fossa Ependymoma, Not Elsewhere Classified&apos; EquivalentTo &apos;Posterior Fossa Ependymoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Absence of Distinct DNA Methylation Profiling Molecular Group&apos;) and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198590)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186449</classIRI>
<classLabel>Posterior Fossa Ependymoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Posterior Fossa Ependymoma, Not Otherwise Specified&apos; EquivalentTo &apos;Posterior Fossa Ependymoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;DNA Methylation Profiling Status Unknown&apos;)</deletedAxiom>
<newAxiom>&apos;Posterior Fossa Ependymoma, Not Otherwise Specified&apos; EquivalentTo &apos;Posterior Fossa Ependymoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;DNA Methylation Profiling Status Unknown&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186407</classIRI>
<classLabel>Ixoberogene Soroparvovec</classLabel>
<deletedAxiom>&apos;Ixoberogene Soroparvovec&apos; SubClassOf &apos;VEGFR-targeting Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191959</classIRI>
<classLabel>Circulating Tumor HPV DNA</classLabel>
<newAxiom>&apos;Circulating Tumor HPV DNA&apos; SubClassOf &apos;Circulating Cell-Free Human Papillomavirus DNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95946</classIRI>
<classLabel>Ancient DNA</classLabel>
<deletedAxiom>&apos;Ancient DNA&apos; SubClassOf &apos;Biospecimen&apos;</deletedAxiom>
<newAxiom>&apos;Ancient DNA&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198567</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191738</classIRI>
<classLabel>CTLA-4-targeting Agent</classLabel>
<deletedAxiom>&apos;CTLA-4-targeting Agent&apos; SubClassOf &apos;Immune Checkpoint Modulator&apos;</deletedAxiom>
<newAxiom>&apos;CTLA-4-targeting Agent&apos; SubClassOf &apos;Immune Checkpoint Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191850</classIRI>
<classLabel>Anti-CD19-Glucosteroid Receptor Modulator ADC ABBV-31</classLabel>
<deletedAxiom>&apos;Anti-CD19-Glucosteroid Receptor Modulator ADC ABBV-31&apos; SubClassOf &apos;Immunoconjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD19-Glucosteroid Receptor Modulator ADC ABBV-31&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD19-Glucosteroid Receptor Modulator ADC ABBV-31&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198859</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17107</classIRI>
<classLabel>tRNA Methyltransferase</classLabel>
<newAxiom>&apos;tRNA Methyltransferase&apos; SubClassOf &apos;Translation Process Protein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17359</classIRI>
<classLabel>TP53 Gene</classLabel>
<newAxiom>&apos;TP53 Gene&apos; EquivalentTo &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198593</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179475</classIRI>
<classLabel>Ovarian Mixed Germ Cell-Sex Cord-Stromal Tumor, Unclassified</classLabel>
<deletedAxiom>&apos;Ovarian Mixed Germ Cell-Sex Cord-Stromal Tumor, Unclassified&apos; EquivalentTo &apos;Ovarian Mixed Germ Cell-Sex Cord-Stromal Tumor&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Ovarian Mixed Germ Cell-Sex Cord-Stromal Tumor, Unclassified&apos; EquivalentTo &apos;Ovarian Mixed Germ Cell-Sex Cord-Stromal Tumor&apos; and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198590)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C106429</classIRI>
<classLabel>PBTL CD19CAR-28/CD137/zeta</classLabel>
<deletedAxiom>&apos;PBTL CD19CAR-28/CD137/zeta&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;PBTL CD19CAR-28/CD137/zeta&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179168</classIRI>
<classLabel>Anti-CSF1R Monoclonal Antibody AMB-05X</classLabel>
<deletedAxiom>&apos;Anti-CSF1R Monoclonal Antibody AMB-05X&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CSF1R Monoclonal Antibody AMB-05X&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CSF1R Monoclonal Antibody AMB-05X&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198645</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131301</classIRI>
<classLabel>Anti-CSF1 Monoclonal Antibody PD-0360324</classLabel>
<newAxiom>&apos;Anti-CSF1 Monoclonal Antibody PD-0360324&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198644</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170914</classIRI>
<classLabel>Autologous CRISPR-edited Anti-CD19 CAR T Cells XYF19</classLabel>
<deletedAxiom>&apos;Autologous CRISPR-edited Anti-CD19 CAR T Cells XYF19&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous CRISPR-edited Anti-CD19 CAR T Cells XYF19&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170905</classIRI>
<classLabel>Autologous 1928T2z CAR T-cells WZTL-002</classLabel>
<deletedAxiom>&apos;Autologous 1928T2z CAR T-cells WZTL-002&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous 1928T2z CAR T-cells WZTL-002&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170909</classIRI>
<classLabel>Anti-PD-1/VEGF Bispecific Antibody AK112</classLabel>
<newAxiom>&apos;Anti-PD-1/VEGF Bispecific Antibody AK112&apos; SubClassOf &apos;Anti-VEGF Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17843</classIRI>
<classLabel>Epidemiologist</classLabel>
<deletedAxiom>&apos;Epidemiologist&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Epidemiologist&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179290</classIRI>
<classLabel>CD8-depleted Non-engrafting HLA-mismatched Unrelated Donor Lymphocytes</classLabel>
<deletedAxiom>&apos;CD8-depleted Non-engrafting HLA-mismatched Unrelated Donor Lymphocytes&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179281</classIRI>
<classLabel>CD19-targeted CAR T2 Cells</classLabel>
<deletedAxiom>&apos;CD19-targeted CAR T2 Cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;CD19-targeted CAR T2 Cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4340</classIRI>
<classLabel>Peripheral T-Cell Lymphoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; EquivalentTo &apos;Aggressive T-Cell Non-Hodgkin Lymphoma&apos; and &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Peripheral (Post-Thymic) T-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Neoplastic Cells with TFH Cell Phenotype Present&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;)</deletedAxiom>
<newAxiom>&apos;Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; EquivalentTo &apos;Aggressive T-Cell Non-Hodgkin Lymphoma&apos; and &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Peripheral (Post-Thymic) T-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Neoplastic Cells with TFH Cell Phenotype Present&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62196</classIRI>
<classLabel>Salivary Gland Adenocarcinoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Salivary Gland Adenocarcinoma, Not Otherwise Specified&apos; EquivalentTo &apos;Salivary Gland Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Non-Specific Glandular Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Duct-Like Structures Present&apos;)</deletedAxiom>
<newAxiom>&apos;Salivary Gland Adenocarcinoma, Not Otherwise Specified&apos; EquivalentTo &apos;Salivary Gland Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Non-Specific Glandular Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Duct-Like Structures Present&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C184564</classIRI>
<classLabel>U-47700 Measurement</classLabel>
<deletedAxiom>&apos;U-47700 Measurement&apos; SubClassOf &apos;Opioid Measurement&apos;</deletedAxiom>
<newAxiom>&apos;U-47700 Measurement&apos; SubClassOf &apos;Synthetic Cannabinoid Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62528</classIRI>
<classLabel>Blinatumomab</classLabel>
<deletedAxiom>&apos;Blinatumomab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Blinatumomab&apos; SubClassOf &apos;Anti-CD19 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185293</classIRI>
<classLabel>Myeloid Neoplasms with Germline SAMD9 Mutation</classLabel>
<deletedAxiom>&apos;Myeloid Neoplasms with Germline SAMD9 Mutation&apos; EquivalentTo &apos;Myeloid Neoplasms with Germline Predisposition Associated with Other Organ Dysfunction&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;SAMD9 Gene Mutation&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;SAMD9L Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Myeloid Neoplasms with Germline SAMD9 Mutation&apos; EquivalentTo &apos;Myeloid Neoplasms with Germline Predisposition Associated with Other Organ Dysfunction&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;SAMD9 Gene Mutation&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;SAMD9 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C151921</classIRI>
<classLabel>Myeloid Neoplasms with Germline Predisposition Associated with Telomerase Biology Disorders</classLabel>
<deletedAxiom>&apos;Myeloid Neoplasms with Germline Predisposition Associated with Telomerase Biology Disorders&apos; EquivalentTo &apos;Myeloid Neoplasms with Germline Predisposition Associated with Other Organ Dysfunction&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Telomere Maintenance Gene Mutation&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;Telomere Maintenance Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Myeloid Neoplasms with Germline Predisposition Associated with Telomerase Biology Disorders&apos; EquivalentTo &apos;Myeloid Neoplasms with Germline Predisposition Associated with Inherited Bone Marrow Failure Syndromes&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Telomere Maintenance Gene Mutation&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;Telomere Maintenance Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126958</classIRI>
<classLabel>Complement C2</classLabel>
<deletedAxiom>&apos;Complement C2&apos; EquivalentTo &apos;Complement Component Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Classical Complement Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Complement Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Lectin Induced Complement Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Systemic Lupus Erythematosus Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Complement and Coagulation Cascade&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Extracellular Space&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;C2 Deficiency&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Protease Domain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Sushi Domain&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Serine Protease&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immunity&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Proteolytic Processing&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Complement Activation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;C2 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Complement C2&apos; EquivalentTo &apos;Serine Protease&apos; and &apos;Complement Component Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Classical Complement Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Complement Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Lectin Induced Complement Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Systemic Lupus Erythematosus Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Complement and Coagulation Cascade&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Extracellular Space&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;C2 Deficiency&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Sushi Domain&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Serine Protease&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immunity&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Proteolytic Processing&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Complement Activation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;C2 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C151975</classIRI>
<classLabel>Acute Leukemia of Ambiguous Lineage, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Acute Leukemia of Ambiguous Lineage, Not Otherwise Specified&apos; EquivalentTo &apos;Acute Leukemia of Ambiguous Lineage&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Leukemia of Ambiguous Lineage, Not Otherwise Specified&apos; EquivalentTo &apos;Acute Leukemia of Ambiguous Lineage&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Blasts Expressing B-Lymphoid and Myeloid Markers Present&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C151935</classIRI>
<classLabel>Anti-CD19/CD20/CD22/CD30 CAR-T Cells</classLabel>
<newAxiom>&apos;Anti-CD19/CD20/CD22/CD30 CAR-T Cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C151944</classIRI>
<classLabel>Autologous PD1-inhibiting Anti-CD19 4-1BB CAR T Cells</classLabel>
<deletedAxiom>&apos;Autologous PD1-inhibiting Anti-CD19 4-1BB CAR T Cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous PD1-inhibiting Anti-CD19 4-1BB CAR T Cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126644</classIRI>
<classLabel>Anti-VEGF/ANG2 Nanobody BI 836880</classLabel>
<newAxiom>&apos;Anti-VEGF/ANG2 Nanobody BI 836880&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198860</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96561</classIRI>
<classLabel>Adjudicator</classLabel>
<deletedAxiom>&apos;Adjudicator&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Adjudicator&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185185</classIRI>
<classLabel>Astrocytoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Astrocytoma, Not Otherwise Specified&apos; EquivalentTo &apos;Astrocytoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;IDH Gene Family Mutation Status Unknown&apos;)</deletedAxiom>
<newAxiom>&apos;Astrocytoma, Not Otherwise Specified&apos; EquivalentTo &apos;Astrocytoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;IDH Gene Family Mutation Status Unknown&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96761</classIRI>
<classLabel>Unclassified Hepatocellular Adenoma</classLabel>
<deletedAxiom>&apos;Unclassified Hepatocellular Adenoma&apos; EquivalentTo &apos;Hepatocellular Adenoma&apos; and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Molecular Genetic Variation&apos;)</deletedAxiom>
<newAxiom>&apos;Unclassified Hepatocellular Adenoma&apos; EquivalentTo &apos;Hepatocellular Adenoma&apos; and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198590) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Molecular Genetic Variation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82212</classIRI>
<classLabel>Mixed Phenotype Acute Leukemia, B/Myeloid, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Mixed Phenotype Acute Leukemia, B/Myeloid, Not Otherwise Specified&apos; EquivalentTo &apos;Mixed Phenotype Acute Leukemia&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Blasts Expressing B-Lymphoid and Myeloid Markers Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Unfavorable Clinical Outcome&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(9;22)(q34.1;q11.2)&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(v;11q23.3)&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Blasts Expressing B-Lymphoid, T-Lymphoid, and Myeloid Markers Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Blasts Expressing B-Lymphoid and T-Lymphoid Markers Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Blasts Expressing CD56 and Immature T-Cell Markers Present&apos;)</deletedAxiom>
<newAxiom>&apos;Mixed Phenotype Acute Leukemia, B/Myeloid, Not Otherwise Specified&apos; EquivalentTo &apos;Mixed Phenotype Acute Leukemia&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Blasts Expressing B-Lymphoid and Myeloid Markers Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Unfavorable Clinical Outcome&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(9;22)(q34.1;q11.2)&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(v;11q23.3)&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Blasts Expressing B-Lymphoid, T-Lymphoid, and Myeloid Markers Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Blasts Expressing B-Lymphoid and T-Lymphoid Markers Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Blasts Expressing CD56 and Immature T-Cell Markers Present&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96801</classIRI>
<classLabel>Anti-CSF1R Monoclonal Antibody IMC-CS4</classLabel>
<deletedAxiom>&apos;Anti-CSF1R Monoclonal Antibody IMC-CS4&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CSF1R Monoclonal Antibody IMC-CS4&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CSF1R Monoclonal Antibody IMC-CS4&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198645</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82338</classIRI>
<classLabel>Myeloid Proliferations Associated with Down Syndrome</classLabel>
<deletedAxiom>&apos;Myeloid Proliferations Associated with Down Syndrome&apos; EquivalentTo &apos;Myeloid Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Marrow&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Hematopoietic Stem Cell&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;Trisomy 21&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Down Syndrome&apos;)</deletedAxiom>
<newAxiom>&apos;Myeloid Proliferations Associated with Down Syndrome&apos; EquivalentTo &apos;Myeloid Neoplasms with Germline Predisposition Associated with Other Organ Dysfunction&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Marrow&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Hematopoietic Stem Cell&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;Trisomy 21&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Down Syndrome&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82375</classIRI>
<classLabel>Anti-CD19/Anti-CD22 Bispecific Immunotoxin DT2219ARL</classLabel>
<newAxiom>&apos;Anti-CD19/Anti-CD22 Bispecific Immunotoxin DT2219ARL&apos; SubClassOf &apos;Anti-CD19 Immunotoxins&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82433</classIRI>
<classLabel>Acute Myeloid Leukemia with CEBPA Mutation</classLabel>
<deletedAxiom>&apos;Acute Myeloid Leukemia with CEBPA Mutation&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Gene Mutations&apos; and &apos;Childhood Acute Myeloid Leukemia&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;CEBPA Gene Mutation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Favorable Clinical Outcome&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Germline Variation&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Hereditary Lesion&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CEBPA Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Myeloid Leukemia with CEBPA Mutation&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Gene Mutations&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;CEBPA Gene Mutation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Favorable Clinical Outcome&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Germline Variation&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Hereditary Lesion&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CEBPA Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82431</classIRI>
<classLabel>Acute Myeloid Leukemia with NPM1 Mutation</classLabel>
<deletedAxiom>&apos;Acute Myeloid Leukemia with NPM1 Mutation&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Gene Mutations&apos; and &apos;Childhood Acute Myeloid Leukemia&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;NPM1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Favorable Clinical Outcome&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;NPM1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Myeloid Leukemia with NPM1 Mutation&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Gene Mutations&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;NPM1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Favorable Clinical Outcome&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;NPM1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82426</classIRI>
<classLabel>Acute Myeloid Leukemia with inv(3) (q21.3;q26.2) or t(3;3) (q21.3;q26.2); GATA2, MECOM</classLabel>
<deletedAxiom>&apos;Acute Myeloid Leukemia with inv(3) (q21.3;q26.2) or t(3;3) (q21.3;q26.2); GATA2, MECOM&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Recurrent Genetic Abnormalities&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Bone Marrow Dysplasia Present&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MECOM Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Myeloid Leukemia with inv(3) (q21.3;q26.2) or t(3;3) (q21.3;q26.2); GATA2, MECOM&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Recurrent Genetic Abnormalities&apos; and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;MECOM Gene Rearrangement&apos;) and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198845) and (&apos;Disease_Has_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Bone Marrow Dysplasia Present&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MECOM Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82403</classIRI>
<classLabel>Acute Myeloid Leukemia with t(9;11)(p21.3;q23.3); MLLT3-MLL</classLabel>
<deletedAxiom>&apos;Acute Myeloid Leukemia with t(9;11)(p21.3;q23.3); MLLT3-MLL&apos; EquivalentTo &apos;Acute Myeloid Leukemia with MLL Rearrangement&apos; and ((&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;MLLT3-KMT2A Fusion Protein Expression&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;t(9;11)(p21.3;q23.3)&apos;)) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Multipotent Bone Marrow Stem Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Disseminated Intravascular Coagulation&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MLL/MLLT3 Fusion Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Myeloid Leukemia with t(9;11)(p21.3;q23.3); MLLT3-MLL&apos; EquivalentTo &apos;Acute Myeloid Leukemia with MLL Rearrangement&apos; and ((&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;MLLT3-KMT2A Fusion Protein Expression&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;t(9;11)(p21.3;q23.3)&apos;)) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;MLLT3 Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Disseminated Intravascular Coagulation&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MLL/MLLT3 Fusion Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82491</classIRI>
<classLabel>Multiple Product Administrator</classLabel>
<deletedAxiom>&apos;Multiple Product Administrator&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Multiple Product Administrator&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126377</classIRI>
<classLabel>Anti-CD19 Antibody-drug Conjugate SGN-CD19B</classLabel>
<deletedAxiom>&apos;Anti-CD19 Antibody-drug Conjugate SGN-CD19B&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD19 Antibody-drug Conjugate SGN-CD19B&apos; SubClassOf &apos;Immunoconjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD19 Antibody-drug Conjugate SGN-CD19B&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198859</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82591</classIRI>
<classLabel>Myelodysplastic Syndrome with Single Lineage Dysplasia</classLabel>
<deletedAxiom>&apos;Myelodysplastic Syndrome with Single Lineage Dysplasia&apos; EquivalentTo &apos;Myelodysplastic Syndrome&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unilineage Dysplasia Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Ring Sideroblasts 15 Percent or More of Erythroid Precursors&apos;)</deletedAxiom>
<newAxiom>&apos;Myelodysplastic Syndrome with Single Lineage Dysplasia&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198589 and (&apos;Disease_Has_Finding&apos; some &apos;Unilineage Dysplasia Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Ring Sideroblasts 15 Percent or More of Erythroid Precursors&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82596</classIRI>
<classLabel>Refractory Cytopenia of Childhood</classLabel>
<deletedAxiom>&apos;Refractory Cytopenia of Childhood&apos; EquivalentTo &apos;Childhood Myelodysplastic Syndrome&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Cytopenia&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 2 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 5 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Monosomy 7&apos;) and (&apos;Disease_Mapped_To_Chromosome&apos; some &apos;Human Chromosome 7&apos;)</deletedAxiom>
<newAxiom>&apos;Refractory Cytopenia of Childhood&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198663 and &apos;Childhood Hematopoietic and Lymphoid Cell Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Cytopenia&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 2 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 5 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Bone Marrow Dysplasia Present&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Dyskeratosis Congenita&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Shwachman-Diamond Syndrome&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Fanconi Anemia&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Bone Marrow Fibrosis&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Germline Variation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Somatic Variation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165774</classIRI>
<classLabel>Anti-CD19-CAR-CD28/CD20-CAR-4-1BB-expressing Autologous T-lymphocytes Hu1928-Hu20BB</classLabel>
<newAxiom>&apos;Anti-CD19-CAR-CD28/CD20-CAR-4-1BB-expressing Autologous T-lymphocytes Hu1928-Hu20BB&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82616</classIRI>
<classLabel>Myelodysplastic/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis</classLabel>
<deletedAxiom>&apos;Myelodysplastic/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis&apos; EquivalentTo &apos;Myelodysplastic/Myeloproliferative Neoplasm&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Abnormal Megakaryocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Dysplastic Erythroid Precursor&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Thrombocytosis&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 5 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Ring Sideroblasts 15 Percent or More of Erythroid Precursors&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 1 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Bone Marrow Dysplasia Present&apos;)</deletedAxiom>
<newAxiom>&apos;Myelodysplastic/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis&apos; EquivalentTo &apos;Myelodysplastic/Myeloproliferative Neoplasm&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Abnormal Megakaryocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Dysplastic Erythroid Precursor&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Thrombocytosis&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 5 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Ring Sideroblasts 15 Percent or More of Erythroid Precursors&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 1 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Bone Marrow Dysplasia Present&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;SF3B1 Gene Mutation&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198558)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C190719</classIRI>
<classLabel>Lanreotide Regimen</classLabel>
<newAxiom>&apos;Lanreotide Regimen&apos; SubClassOf &apos;Regimen Used to Treat Appendiceal Cancer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C190707</classIRI>
<classLabel>CD19R(EQ)-CD28-CD3zeta-EGFRt-expressing T-lymphocytes</classLabel>
<deletedAxiom>&apos;CD19R(EQ)-CD28-CD3zeta-EGFRt-expressing T-lymphocytes&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;CD19R(EQ)-CD28-CD3zeta-EGFRt-expressing T-lymphocytes&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165769</classIRI>
<classLabel>Bioinformatician</classLabel>
<deletedAxiom>&apos;Bioinformatician&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Bioinformatician&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165551</classIRI>
<classLabel>Anti-CD19 CAR T-cells XLCART001</classLabel>
<deletedAxiom>&apos;Anti-CD19 CAR T-cells XLCART001&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD19 CAR T-cells XLCART001&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18364</classIRI>
<classLabel>CBL Gene</classLabel>
<newAxiom>&apos;CBL Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198681</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18392</classIRI>
<classLabel>MECOM Gene</classLabel>
<newAxiom>&apos;MECOM Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198846</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43368</classIRI>
<classLabel>Editor</classLabel>
<deletedAxiom>&apos;Editor&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
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<newAxiom>&apos;Glioblastoma, Not Otherwise Specified&apos; EquivalentTo &apos;Glioblastoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;IDH Gene Family Mutation Status Unknown&apos;)</newAxiom>
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<newAxiom>&apos;Recurrent Juvenile Myelomonocytic Leukemia&apos; EquivalentTo &apos;Recurrent Childhood Malignant Neoplasm&apos; and &apos;Recurrent Myeloid Neoplasm&apos; and &apos;Juvenile Myelomonocytic Leukemia&apos;</newAxiom>
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<classLabel>Retrobulbar Route of Administration</classLabel>
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<classLabel>Intracorneal Route of Administration</classLabel>
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<deletedAxiom>&apos;Intracorneal Route of Administration&apos; SubClassOf &apos;Parenteral Route of Administration&apos;</deletedAxiom>
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<classLabel>Intraocular Route of Administration</classLabel>
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<deletedAxiom>&apos;Intraocular Route of Administration&apos; SubClassOf &apos;Ophthalmic Route of Administration&apos;</deletedAxiom>
<newAxiom>&apos;Intraocular Route of Administration&apos; SubClassOf &apos;Route of Administration&apos;</newAxiom>
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<classLabel>t(17;17)(q21;q21)</classLabel>
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<newAxiom>&apos;Cisplatin/Docetaxel Regimen&apos; SubClassOf &apos;Regimen Used to Treat Gastric Carcinoma&apos;</newAxiom>
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<classLabel>TPF Regimen</classLabel>
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<classLabel>Docetaxel/Gemcitabine Regimen</classLabel>
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<newAxiom>&apos;Docetaxel/Gemcitabine Regimen&apos; SubClassOf &apos;Regimen Used to Treat Bone Cancer&apos;</newAxiom>
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<classLabel>CAP Regimen</classLabel>
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<newAxiom>&apos;CAP Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Thymus Neoplasm&apos;</newAxiom>
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<classLabel>CD20-CD19 Compound CAR T Cells</classLabel>
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<changedClass>
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<classLabel>Interviewer</classLabel>
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<classLabel>FCR Regimen</classLabel>
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<classLabel>CSF1R Inhibitor ABSK021</classLabel>
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<newAxiom>&apos;CSF1R Inhibitor ABSK021&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198646</newAxiom>
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<classLabel>CSF3R Gene</classLabel>
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<classLabel>FLT3 Gene</classLabel>
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<classLabel>JAK2 Gene</classLabel>
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<deletedAxiom>&apos;JAK2 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Primary Myelofibrosis&apos;</deletedAxiom>
<deletedAxiom>&apos;JAK2 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Polycythemia Vera&apos;</deletedAxiom>
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<newAxiom>&apos;PAX5 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198684</newAxiom>
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<classLabel>Healthcare Practitioners and Technical Occupations</classLabel>
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<classLabel>Education, Training and Library Occupations</classLabel>
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<newAxiom>&apos;Education, Training and Library Occupations&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Farming, Fishing, and Forestry Occupations</classLabel>
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<newAxiom>&apos;Farming, Fishing, and Forestry Occupations&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Management Occupations</classLabel>
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<newAxiom>&apos;Management Occupations&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Construction and Extraction Occupations</classLabel>
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<newAxiom>&apos;Construction and Extraction Occupations&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97626</classIRI>
<classLabel>Building and Grounds Clearing and Maintenance Occupations</classLabel>
<deletedAxiom>&apos;Building and Grounds Clearing and Maintenance Occupations&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Building and Grounds Clearing and Maintenance Occupations&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97627</classIRI>
<classLabel>Business and Financial Operations Occupations</classLabel>
<deletedAxiom>&apos;Business and Financial Operations Occupations&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Business and Financial Operations Occupations&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97624</classIRI>
<classLabel>Architecture and Engineering Occupations</classLabel>
<deletedAxiom>&apos;Architecture and Engineering Occupations&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Architecture and Engineering Occupations&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97625</classIRI>
<classLabel>Arts, Design, Entertainment, Sports and Media Occupations</classLabel>
<deletedAxiom>&apos;Arts, Design, Entertainment, Sports and Media Occupations&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Arts, Design, Entertainment, Sports and Media Occupations&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97628</classIRI>
<classLabel>Community and Social Services Occupations</classLabel>
<deletedAxiom>&apos;Community and Social Services Occupations&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Community and Social Services Occupations&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97629</classIRI>
<classLabel>Computer and Mathematical Occupations</classLabel>
<deletedAxiom>&apos;Computer and Mathematical Occupations&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Computer and Mathematical Occupations&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160091</classIRI>
<classLabel>Nilotinib Regimen</classLabel>
<deletedAxiom>&apos;Nilotinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Intestinal Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Nilotinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Myeloid Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Nilotinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Soft Tissue Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Nilotinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Lymphocytic Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160074</classIRI>
<classLabel>Larotrectinib Regimen</classLabel>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Vulvar Cancer&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Ovarian Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Hepatobiliary Cancer&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Cervical Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Fallopian Tube Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Melanoma&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Intestinal Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Central Nervous System Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Breast Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Thyroid Cancer&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Gastric Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Esophageal Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Soft Tissue Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Pancreatic Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Colorectal Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Larotrectinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Sarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160073</classIRI>
<classLabel>Lapatinib Regimen</classLabel>
<newAxiom>&apos;Lapatinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Breast Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160024</classIRI>
<classLabel>Docetaxel Regimen</classLabel>
<newAxiom>&apos;Docetaxel Regimen&apos; SubClassOf &apos;Regimen Used to Treat Small Cell Lung Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Docetaxel Regimen&apos; SubClassOf &apos;Regimen Used to Treat Breast Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Docetaxel Regimen&apos; SubClassOf &apos;Regimen Used to Treat Sarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160001</classIRI>
<classLabel>Bortezomib Regimen</classLabel>
<newAxiom>&apos;Bortezomib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Acute Lymphoblastic Leukemia&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174397</classIRI>
<classLabel>Allogeneic Anti-CD20 CAR T-cells LUCAR-20S</classLabel>
<deletedAxiom>&apos;Allogeneic Anti-CD20 CAR T-cells LUCAR-20S&apos; SubClassOf &apos;CD20-targeting Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174412</classIRI>
<classLabel>BCMA-CD19 Compound CAR T Cells</classLabel>
<newAxiom>&apos;BCMA-CD19 Compound CAR T Cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174129</classIRI>
<classLabel>Acute Myeloid Leukemia with MLL Rearrangement</classLabel>
<deletedAxiom>&apos;Acute Myeloid Leukemia with MLL Rearrangement&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Recurrent Genetic Abnormalities&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;MLL Gene Rearrangement&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;KMT2A Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Myeloid Leukemia with MLL Rearrangement&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Recurrent Genetic Abnormalities&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Multipotent Bone Marrow Stem Cell&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;MLL Gene Rearrangement&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;KMT2A Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174108</classIRI>
<classLabel>Nucleic RNA Sample</classLabel>
<deletedAxiom>&apos;Nucleic RNA Sample&apos; SubClassOf &apos;Biospecimen&apos;</deletedAxiom>
<newAxiom>&apos;Nucleic RNA Sample&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198568</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101258</classIRI>
<classLabel>CD19CAR-CD3zeta-4-1BB-expressing Allogeneic T-lymphocyte Cells</classLabel>
<deletedAxiom>&apos;CD19CAR-CD3zeta-4-1BB-expressing Allogeneic T-lymphocyte Cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;CD19CAR-CD3zeta-4-1BB-expressing Allogeneic T-lymphocyte Cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174216</classIRI>
<classLabel>Congenital Myasthenic Syndrome-4C</classLabel>
<newAxiom>&apos;Congenital Myasthenic Syndrome-4C&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198628</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C188352</classIRI>
<classLabel>N6-Methyladenine Enriched RNA</classLabel>
<deletedAxiom>&apos;N6-Methyladenine Enriched RNA&apos; SubClassOf &apos;Biospecimen&apos;</deletedAxiom>
<newAxiom>&apos;N6-Methyladenine Enriched RNA&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198568</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8574</classIRI>
<classLabel>Myelodysplastic Syndrome with Multilineage Dysplasia</classLabel>
<deletedAxiom>&apos;Myelodysplastic Syndrome with Multilineage Dysplasia&apos; EquivalentTo &apos;Myelodysplastic Syndrome&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Bone Marrow Myeloid Stem Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Multilineage Dysplasia Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 5 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 1 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Bone Marrow Dysplasia Present in 10 Percent or More of the Cells of Two or More Myeloid Cell Lines&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Micromegakaryocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neutrophil with Pseudo Pelger-Huet Nucleus&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Hypolobated Megakaryocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Dysplastic Granulocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Dysplastic Erythroid Precursor&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neutrophil with Cytoplasmic Hypogranularity&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Trisomy 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 7q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Monosomy 7&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Monosomy 5&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Erythroid Hyperplasia&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Ring Sideroblasts 15 Percent or More of Erythroid Precursors&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Auer Rods Present&apos;)</deletedAxiom>
<newAxiom>&apos;Myelodysplastic Syndrome with Multilineage Dysplasia&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198589 and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Bone Marrow Myeloid Stem Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Multilineage Dysplasia Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 5 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 1 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Bone Marrow Dysplasia Present in 10 Percent or More of the Cells of Two or More Myeloid Cell Lines&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Micromegakaryocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neutrophil with Pseudo Pelger-Huet Nucleus&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Hypolobated Megakaryocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Dysplastic Granulocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Dysplastic Erythroid Precursor&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neutrophil with Cytoplasmic Hypogranularity&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Trisomy 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 7q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Monosomy 7&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Monosomy 5&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Erythroid Hyperplasia&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Ring Sideroblasts 15 Percent or More of Erythroid Precursors&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Auer Rods Present&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129785</classIRI>
<classLabel>Acute Myeloid Leukemia with BCR-ABL1</classLabel>
<deletedAxiom>&apos;Acute Myeloid Leukemia with BCR-ABL1&apos; EquivalentTo &apos;Acute Myeloid Leukemia with Recurrent Genetic Abnormalities&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BCR/ABL1 Fusion Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Myeloid Leukemia with BCR-ABL1&apos; EquivalentTo &apos;Acute Myeloid Leukemia&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Blasts 20 Percent or More of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BCR/ABL1 Fusion Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115101</classIRI>
<classLabel>Anti-CD19/CD3 Tetravalent Antibody AFM11</classLabel>
<deletedAxiom>&apos;Anti-CD19/CD3 Tetravalent Antibody AFM11&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD19/CD3 Tetravalent Antibody AFM11&apos; SubClassOf &apos;Anti-CD19 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129853</classIRI>
<classLabel>Myeloid/Lymphoid Neoplasms with PCM1-JAK2</classLabel>
<deletedAxiom>&apos;Myeloid/Lymphoid Neoplasms with PCM1-JAK2&apos; EquivalentTo &apos;Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2&apos; and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;t(8;9)(p22;p24.1)&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Eosinophilia&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;PCM1/JAK2 Fusion Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Myeloid/Lymphoid Neoplasms with PCM1-JAK2&apos; EquivalentTo &apos;Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;JAK2 Gene Rearrangement&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;t(8;9)(p22;p24.1)&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Eosinophilia&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;PCM1/JAK2 Fusion Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19612</classIRI>
<classLabel>Legislative Liaison</classLabel>
<deletedAxiom>&apos;Legislative Liaison&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Legislative Liaison&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129531</classIRI>
<classLabel>Retailer</classLabel>
<deletedAxiom>&apos;Retailer&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Retailer&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129688</classIRI>
<classLabel>CSF1R Inhibitor PLX73086</classLabel>
<deletedAxiom>&apos;CSF1R Inhibitor PLX73086&apos; SubClassOf &apos;Immunosuppressant&apos;</deletedAxiom>
<newAxiom>&apos;CSF1R Inhibitor PLX73086&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198646</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129653</classIRI>
<classLabel>Sotuletinib</classLabel>
<deletedAxiom>&apos;Sotuletinib&apos; SubClassOf &apos;Immunosuppressant&apos;</deletedAxiom>
<newAxiom>&apos;Sotuletinib&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198646</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168975</classIRI>
<classLabel>Ehlers-Danlos Syndrome, Musculocontractural Type 1</classLabel>
<newAxiom>&apos;Ehlers-Danlos Syndrome, Musculocontractural Type 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198631</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129323</classIRI>
<classLabel>Oligoastrocytoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Oligoastrocytoma, Not Otherwise Specified&apos; EquivalentTo &apos;Oligoastrocytoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;IDH Gene Family Mutation Status Unknown&apos;)</deletedAxiom>
<newAxiom>&apos;Oligoastrocytoma, Not Otherwise Specified&apos; EquivalentTo &apos;Oligoastrocytoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;IDH Gene Family Mutation Status Unknown&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129324</classIRI>
<classLabel>Anaplastic Oligoastrocytoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Anaplastic Oligoastrocytoma, Not Otherwise Specified&apos; EquivalentTo &apos;Anaplastic Oligoastrocytoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;IDH Gene Family Mutation Status Unknown&apos;)</deletedAxiom>
<newAxiom>&apos;Anaplastic Oligoastrocytoma, Not Otherwise Specified&apos; EquivalentTo &apos;Anaplastic Oligoastrocytoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;IDH Gene Family Mutation Status Unknown&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129322</classIRI>
<classLabel>Anaplastic Oligodendroglioma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Anaplastic Oligodendroglioma, Not Otherwise Specified&apos; EquivalentTo &apos;Anaplastic Oligodendroglioma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;IDH Gene Family Mutation Status Unknown&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;1p/19q Codeletion Status Unknown&apos;)</deletedAxiom>
<newAxiom>&apos;Anaplastic Oligodendroglioma, Not Otherwise Specified&apos; EquivalentTo &apos;Anaplastic Oligodendroglioma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;IDH Gene Family Mutation Status Unknown&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;1p/19q Codeletion Status Unknown&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129319</classIRI>
<classLabel>Oligodendroglioma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Oligodendroglioma, Not Otherwise Specified&apos; EquivalentTo &apos;Oligodendroglioma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;IDH Gene Family Mutation Status Unknown&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;1p/19q Codeletion Status Unknown&apos;)</deletedAxiom>
<newAxiom>&apos;Oligodendroglioma, Not Otherwise Specified&apos; EquivalentTo &apos;Oligodendroglioma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;IDH Gene Family Mutation Status Unknown&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;1p/19q Codeletion Status Unknown&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8648</classIRI>
<classLabel>Myelodysplastic Syndrome, Unclassifiable</classLabel>
<deletedAxiom>&apos;Myelodysplastic Syndrome, Unclassifiable&apos; EquivalentTo &apos;Myelodysplastic Syndrome&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Bone Marrow Myeloid Stem Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Dysplastic Erythroid Precursor&apos;)</deletedAxiom>
<newAxiom>&apos;Myelodysplastic Syndrome, Unclassifiable&apos; EquivalentTo &apos;Myelodysplastic Syndrome&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Bone Marrow Myeloid Stem Cell&apos;) and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198590) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Dysplastic Erythroid Precursor&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78823</classIRI>
<classLabel>Autologous PBTL CD19CAR-28 zeta</classLabel>
<deletedAxiom>&apos;Autologous PBTL CD19CAR-28 zeta&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous PBTL CD19CAR-28 zeta&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78824</classIRI>
<classLabel>Autologous EBV-CTL CD19CAR zeta</classLabel>
<deletedAxiom>&apos;Autologous EBV-CTL CD19CAR zeta&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous EBV-CTL CD19CAR zeta&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133718</classIRI>
<classLabel>Vadacabtagene Leraleucel</classLabel>
<deletedAxiom>&apos;Vadacabtagene Leraleucel&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Vadacabtagene Leraleucel&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6924</classIRI>
<classLabel>Acute Myeloid Leukemia with Variant MLL Translocations</classLabel>
<deletedAxiom>&apos;Acute Myeloid Leukemia with Variant MLL Translocations&apos; EquivalentTo &apos;Acute Myeloid Leukemia with MLL Rearrangement&apos; and (((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(4;11)(q21;q23)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KMT2A-AF4 Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(11;19)(q23;p13.1)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KMT2A-ENL Fusion Protein Expression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KMT2A-ELL Fusion Protein Expression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KMT2A-EEN Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(10;11)(p11;q23)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KMT2A-AF10 Fusion Protein Expression&apos;))) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Multipotent Bone Marrow Stem Cell&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MLL/AFF1 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MLL/MLLT1 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MLL/MLLT10 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MLLT10/CLP1 Fusion Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Myeloid Leukemia with Variant MLL Translocations&apos; EquivalentTo &apos;Acute Myeloid Leukemia with MLL Rearrangement&apos; and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;MLLT3 Gene Rearrangement&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172841</classIRI>
<classLabel>Autologous UCD19 CAR T Cells</classLabel>
<deletedAxiom>&apos;Autologous UCD19 CAR T Cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous UCD19 CAR T Cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133189</classIRI>
<classLabel>Autologous EGFRt/19-28z/4-1BBL CAR T-Lymphocytes</classLabel>
<deletedAxiom>&apos;Autologous EGFRt/19-28z/4-1BBL CAR T-Lymphocytes&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous EGFRt/19-28z/4-1BBL CAR T-Lymphocytes&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133191</classIRI>
<classLabel>Autologous Human Anti-CD19CAR-4-1BB-CD3zeta-EGFRt-expressing CD4+/CD8+ T-lymphocytes</classLabel>
<deletedAxiom>&apos;Autologous Human Anti-CD19CAR-4-1BB-CD3zeta-EGFRt-expressing CD4+/CD8+ T-lymphocytes&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Human Anti-CD19CAR-4-1BB-CD3zeta-EGFRt-expressing CD4+/CD8+ T-lymphocytes&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C64731</classIRI>
<classLabel>VD Regimen</classLabel>
<newAxiom>&apos;VD Regimen&apos; SubClassOf &apos;Regimen Used to Treat Primary Amyloidosis&apos;</newAxiom>
<newAxiom>&apos;VD Regimen&apos; SubClassOf &apos;Regimen Used to Treat Castleman disease&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39836</classIRI>
<classLabel>Bladder Adenocarcinoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Bladder Adenocarcinoma, Not Otherwise Specified&apos; EquivalentTo &apos;Bladder Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Non-Specific Glandular Pattern&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Intestinal Metaplasia of Bladder Urothelium&apos;)</deletedAxiom>
<newAxiom>&apos;Bladder Adenocarcinoma, Not Otherwise Specified&apos; EquivalentTo &apos;Bladder Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Non-Specific Glandular Pattern&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Intestinal Metaplasia of Bladder Urothelium&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39978</classIRI>
<classLabel>Ovarian Sex Cord-Stromal Tumor, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Ovarian Sex Cord-Stromal Tumor, Not Otherwise Specified&apos; EquivalentTo &apos;Ovarian Sex Cord-Stromal Tumor&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Ovarian Sex Cord-Stromal Tumor, Not Otherwise Specified&apos; EquivalentTo &apos;Ovarian Sex Cord-Stromal Tumor&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Steroid Cell Proliferation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39979</classIRI>
<classLabel>Ovarian Steroid Cell Tumor, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Ovarian Steroid Cell Tumor, Not Otherwise Specified&apos; EquivalentTo &apos;Ovarian Steroid Cell Tumor&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Ovarian Tissue&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Sex Cord-Stromal Cell Resembling Steroid Hormone-Secreting Cell&apos;) and (&apos;Disease_Excludes_Normal_Cell_Origin&apos; some &apos;Granulosa Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Neoplastic Sertoli Cell&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Small Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Ovarian Steroid Cell Tumor, Not Otherwise Specified&apos; EquivalentTo &apos;Ovarian Steroid Cell Tumor&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Ovarian Tissue&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Sex Cord-Stromal Cell Resembling Steroid Hormone-Secreting Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Excludes_Normal_Cell_Origin&apos; some &apos;Granulosa Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Neoplastic Sertoli Cell&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Small Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39984</classIRI>
<classLabel>Ovarian Leydig Cell Tumor, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Ovarian Leydig Cell Tumor, Not Otherwise Specified&apos; SubClassOf &apos;Ovarian Leydig Cell Tumor&apos;</deletedAxiom>
<newAxiom>&apos;Ovarian Leydig Cell Tumor, Not Otherwise Specified&apos; EquivalentTo &apos;Ovarian Leydig Cell Tumor&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25357</classIRI>
<classLabel>Registrar</classLabel>
<deletedAxiom>&apos;Registrar&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Registrar&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98284</classIRI>
<classLabel>SF3B1 Gene</classLabel>
<newAxiom>&apos;SF3B1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198587</newAxiom>
<newAxiom>&apos;SF3B1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198581</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39912</classIRI>
<classLabel>Testicular Mixed Germ Cell-Sex Cord-Stromal Tumor, Unclassified</classLabel>
<deletedAxiom>&apos;Testicular Mixed Germ Cell-Sex Cord-Stromal Tumor, Unclassified&apos; EquivalentTo &apos;Testicular Mixed Germ Cell-Sex Cord-Stromal Tumor&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Diffuse Pattern&apos;)</deletedAxiom>
<newAxiom>&apos;Testicular Mixed Germ Cell-Sex Cord-Stromal Tumor, Unclassified&apos; EquivalentTo &apos;Testicular Mixed Germ Cell-Sex Cord-Stromal Tumor&apos; and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198590) and (&apos;Disease_Has_Finding&apos; some &apos;Diffuse Pattern&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25392</classIRI>
<classLabel>Manufacturer</classLabel>
<deletedAxiom>&apos;Manufacturer&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Manufacturer&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172387</classIRI>
<classLabel>Autologous CD19/PD-1 Bispecific CAR-T Cells</classLabel>
<newAxiom>&apos;Autologous CD19/PD-1 Bispecific CAR-T Cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172452</classIRI>
<classLabel>Non-Compartmental Analysis Dataset</classLabel>
<deletedAxiom>&apos;Non-Compartmental Analysis Dataset&apos; SubClassOf &apos;Data Set&apos;</deletedAxiom>
<newAxiom>&apos;Non-Compartmental Analysis Dataset&apos; SubClassOf &apos;Analysis Dataset&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113827</classIRI>
<classLabel>RVD Regimen</classLabel>
<newAxiom>&apos;RVD Regimen&apos; SubClassOf &apos;Regimen Used to Treat Primary Amyloidosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113826</classIRI>
<classLabel>Bortezomib/Cyclophosphamide/Dexamethasone Regimen</classLabel>
<newAxiom>&apos;Bortezomib/Cyclophosphamide/Dexamethasone Regimen&apos; SubClassOf &apos;Regimen Used to Treat Primary Amyloidosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172195</classIRI>
<classLabel>FLT3/KIT/CSF1R Inhibitor NMS-03592088</classLabel>
<newAxiom>&apos;FLT3/KIT/CSF1R Inhibitor NMS-03592088&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198646</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C50705</classIRI>
<classLabel>Posttraumatic Wound Infection</classLabel>
<deletedAxiom>&apos;Posttraumatic Wound Infection&apos; SubClassOf &apos;Wound Infection&apos;</deletedAxiom>
<newAxiom>&apos;Posttraumatic Wound Infection&apos; SubClassOf &apos;Infectious Disorder&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186728</classIRI>
<classLabel>Anti-CD19/CD20/CD22 CAR T-Cells</classLabel>
<newAxiom>&apos;Anti-CD19/CD20/CD22 CAR T-Cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C50803</classIRI>
<classLabel>Ventriculomeglia</classLabel>
<deletedAxiom>&apos;Ventriculomeglia&apos; SubClassOf &apos;Abnormality of Ventricle&apos;</deletedAxiom>
<newAxiom>&apos;Ventriculomeglia&apos; SubClassOf &apos;Non-Neoplastic Brain Disorder&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84270</classIRI>
<classLabel>Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2</classLabel>
<deletedAxiom>&apos;Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2&apos; EquivalentTo &apos;Hematopoietic and Lymphoid Cell Neoplasm&apos; and &apos;Malignant Neoplasm&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Pluripotent Stem Cell&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;)</deletedAxiom>
<newAxiom>&apos;Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2&apos; EquivalentTo &apos;Hematopoietic and Lymphoid Cell Neoplasm&apos; and &apos;Malignant Neoplasm&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Pluripotent Stem Cell&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198558) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148215</classIRI>
<classLabel>Allogeneic iC9/CD19-CAR-CD28-zeta-2A-IL15-transduced Cord Blood-derived Natural Killer Cells TAK-007</classLabel>
<deletedAxiom>&apos;Allogeneic iC9/CD19-CAR-CD28-zeta-2A-IL15-transduced Cord Blood-derived Natural Killer Cells TAK-007&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148246</classIRI>
<classLabel>Primary Industry of Employment</classLabel>
<deletedAxiom>&apos;Primary Industry of Employment&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Primary Industry of Employment&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84326</classIRI>
<classLabel>Complement Factor D</classLabel>
<deletedAxiom>&apos;Complement Factor D&apos; EquivalentTo &apos;Complement Component Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Alternative Complement Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Serine Protease&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immune Response Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Proteolysis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Host Defense Mechanism&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Complement Activation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CFD Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Complement Factor D&apos; EquivalentTo &apos;Serine Protease&apos; and &apos;Complement Component Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Alternative Complement Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immune Response Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Proteolysis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Host Defense Mechanism&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Complement Activation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CFD Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148249</classIRI>
<classLabel>Processing, Manufacturing, or Utilities</classLabel>
<deletedAxiom>&apos;Processing, Manufacturing, or Utilities&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Processing, Manufacturing, or Utilities&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148248</classIRI>
<classLabel>Trades, Transport, or Construction</classLabel>
<deletedAxiom>&apos;Trades, Transport, or Construction&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Trades, Transport, or Construction&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173076</classIRI>
<classLabel>Anti-HER2 Antibody Conjugated Natural Killer Cells ACE1702</classLabel>
<deletedAxiom>&apos;Anti-HER2 Antibody Conjugated Natural Killer Cells ACE1702&apos; SubClassOf &apos;HER2-targeting Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187655</classIRI>
<classLabel>Anti-CD19 Antibody-drug Conjugate IKS03</classLabel>
<deletedAxiom>&apos;Anti-CD19 Antibody-drug Conjugate IKS03&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD19 Antibody-drug Conjugate IKS03&apos; SubClassOf &apos;Immunoconjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD19 Antibody-drug Conjugate IKS03&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198859</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187704</classIRI>
<classLabel>Age-Related Macular Degeneration-13</classLabel>
<newAxiom>&apos;Age-Related Macular Degeneration-13&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198612</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148156</classIRI>
<classLabel>Autologous CD19CAR-CD28-CD137/CD27/CD3zeta-iCasp9-expressing T-lymphocytes</classLabel>
<deletedAxiom>&apos;Autologous CD19CAR-CD28-CD137/CD27/CD3zeta-iCasp9-expressing T-lymphocytes&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous CD19CAR-CD28-CD137/CD27/CD3zeta-iCasp9-expressing T-lymphocytes&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45234</classIRI>
<classLabel>Wound Infection</classLabel>
<deletedAxiom>&apos;Wound Infection&apos; SubClassOf &apos;Infectious Disorder&apos;</deletedAxiom>
<newAxiom>&apos;Wound Infection&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45231</classIRI>
<classLabel>Diffuse Large B-Cell Lymphoma Unclassifiable</classLabel>
<deletedAxiom>&apos;Diffuse Large B-Cell Lymphoma Unclassifiable&apos; EquivalentTo &apos;Aggressive B-Cell Non-Hodgkin Lymphoma&apos; and &apos;Diffuse Large B-Cell Lymphoma, Not Otherwise Specified by Gene Expression Profile&apos; and (((&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic B-Immunoblast&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Immunoblastic Lymphoma&apos;)) or ((&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Centroblast&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Centroblastic Lymphoma&apos;))) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Cyclin D2 Messenger RNA Overexpression&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;IRF4/MUM1 Messenger RNA Overexpression&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCL2 Gene Translocation&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;REL Gene Amplification&apos;)</deletedAxiom>
<newAxiom>&apos;Diffuse Large B-Cell Lymphoma Unclassifiable&apos; EquivalentTo &apos;Aggressive B-Cell Non-Hodgkin Lymphoma&apos; and &apos;Diffuse Large B-Cell Lymphoma, Not Otherwise Specified by Gene Expression Profile&apos; and (((&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic B-Immunoblast&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Immunoblastic Lymphoma&apos;)) or ((&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Centroblast&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Centroblastic Lymphoma&apos;))) and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198590) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Cyclin D2 Messenger RNA Overexpression&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;IRF4/MUM1 Messenger RNA Overexpression&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCL2 Gene Translocation&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;REL Gene Amplification&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187397</classIRI>
<classLabel>tRNA (Adenine(58)-N(1))-Methyltransferase Catalytic Subunit TRMT61A</classLabel>
<deletedAxiom>&apos;tRNA (Adenine(58)-N(1))-Methyltransferase Catalytic Subunit TRMT61A&apos; SubClassOf &apos;Translation Process Protein&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (Adenine(58)-N(1))-Methyltransferase Catalytic Subunit TRMT61A&apos; SubClassOf &apos;Methyltransferase&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (Adenine(58)-N(1))-Methyltransferase Catalytic Subunit TRMT61A&apos; SubClassOf &apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;tRNA Methyltransferase&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (Adenine(58)-N(1))-Methyltransferase Catalytic Subunit TRMT61A&apos; SubClassOf &apos;tRNA Methyltransferase&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187030</classIRI>
<classLabel>CSF1R Inhibitor HMPL-653</classLabel>
<deletedAxiom>&apos;CSF1R Inhibitor HMPL-653&apos; SubClassOf &apos;Immunosuppressant&apos;</deletedAxiom>
<newAxiom>&apos;CSF1R Inhibitor HMPL-653&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198646</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128696</classIRI>
<classLabel>Peripheral T-Cell Lymphoma, Unclassifiable</classLabel>
<deletedAxiom>&apos;Peripheral T-Cell Lymphoma, Unclassifiable&apos; EquivalentTo &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Peripheral T-Cell Lymphoma, Unclassifiable&apos; EquivalentTo &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte&apos;) and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198590)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128697</classIRI>
<classLabel>NK-Cell Lymphoma, Unclassifiable</classLabel>
<deletedAxiom>&apos;NK-Cell Lymphoma, Unclassifiable&apos; EquivalentTo &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;CD56-Positive Neoplastic Cells Present&apos;)</deletedAxiom>
<newAxiom>&apos;NK-Cell Lymphoma, Unclassifiable&apos; EquivalentTo &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198590) and (&apos;Disease_Has_Finding&apos; some &apos;CD56-Positive Neoplastic Cells Present&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C187129</classIRI>
<classLabel>Anti-CD19/Anti-CD20/Anti-CD22 CAR-T Cells LCAR-AIO</classLabel>
<newAxiom>&apos;Anti-CD19/Anti-CD20/Anti-CD22 CAR-T Cells LCAR-AIO&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C70652</classIRI>
<classLabel>Manager</classLabel>
<deletedAxiom>&apos;Manager&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Manager&apos; SubClassOf &apos;Management Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7168</classIRI>
<classLabel>Myelodysplastic Syndrome with Excess Blasts-2</classLabel>
<deletedAxiom>&apos;Myelodysplastic Syndrome with Excess Blasts-2&apos; EquivalentTo &apos;Myelodysplastic Syndrome with Excess Blasts&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Myeloblasts 10-19 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Myeloblasts 5-19 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Auer Rods Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Unfavorable Clinical Outcome&apos;)</deletedAxiom>
<newAxiom>&apos;Myelodysplastic Syndrome with Excess Blasts-2&apos; EquivalentTo &apos;Myelodysplastic Syndrome&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts 10-19 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts 10-19 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Unfavorable Clinical Outcome&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7167</classIRI>
<classLabel>Myelodysplastic Syndrome with Excess Blasts-1</classLabel>
<deletedAxiom>&apos;Myelodysplastic Syndrome with Excess Blasts-1&apos; EquivalentTo &apos;Myelodysplastic Syndrome with Excess Blasts&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 5 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts 5-9 Percent of Bone Marrow Nucleated Cells&apos;)</deletedAxiom>
<newAxiom>&apos;Myelodysplastic Syndrome with Excess Blasts-1&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7175</classIRI>
<classLabel>Acute Myeloid Leukemia with Recurrent Genetic Abnormalities</classLabel>
<deletedAxiom>&apos;Acute Myeloid Leukemia with Recurrent Genetic Abnormalities&apos; EquivalentTo &apos;Acute Myeloid Leukemia&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Fusion Protein Expression&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;Chromosomal Rearrangement&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Recurrent Genetic Abnormalities Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hypercellular Bone Marrow&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Cytogenetic Abnormalities Not Detected&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Myeloid Leukemia with Recurrent Genetic Abnormalities&apos; EquivalentTo &apos;Acute Myeloid Leukemia&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Fusion Protein Expression&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;Chromosomal Rearrangement&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Blasts 10 Percent or More of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Recurrent Genetic Abnormalities Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hypercellular Bone Marrow&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Cytogenetic Abnormalities Not Detected&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153215</classIRI>
<classLabel>Anti-CD19/CD3 BiTE Antibody AMG 562</classLabel>
<deletedAxiom>&apos;Anti-CD19/CD3 BiTE Antibody AMG 562&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD19/CD3 BiTE Antibody AMG 562&apos; SubClassOf &apos;Anti-CD19 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7717</classIRI>
<classLabel>Malignant Pericardial Effusion</classLabel>
<newAxiom>&apos;Malignant Pericardial Effusion&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198611</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192803</classIRI>
<classLabel>Anti-VEGF/TGF-beta Bispecific Antibody Fusion Protein ZGGS18</classLabel>
<newAxiom>&apos;Anti-VEGF/TGF-beta Bispecific Antibody Fusion Protein ZGGS18&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198860</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7736</classIRI>
<classLabel>Vaginal Squamous Cell Carcinoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Vaginal Squamous Cell Carcinoma, Not Otherwise Specified&apos; EquivalentTo &apos;Vaginal Squamous Cell Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;p16 Immunohistochemistry or HPV Testing Status Unknown&apos;)</deletedAxiom>
<newAxiom>&apos;Vaginal Squamous Cell Carcinoma, Not Otherwise Specified&apos; EquivalentTo &apos;Vaginal Squamous Cell Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;p16 Immunohistochemistry or HPV Testing Status Unknown&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192880</classIRI>
<classLabel>mCode Disease/Finding</classLabel>
<deletedAxiom>&apos;mCode Disease/Finding&apos; SubClassOf &apos;Disease, Disorder or Finding&apos;</deletedAxiom>
<newAxiom>&apos;mCode Disease/Finding&apos; SubClassOf &apos;Finding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7506</classIRI>
<classLabel>Myelodysplastic Syndrome with Excess Blasts</classLabel>
<deletedAxiom>&apos;Myelodysplastic Syndrome with Excess Blasts&apos; EquivalentTo &apos;Myelodysplastic Syndrome&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Bone Marrow Myeloid Stem Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Myeloblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Megaloblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Micromegakaryocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neutrophil with Pseudo Pelger-Huet Nucleus&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Abnormal Platelet&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Hypolobated Megakaryocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Dysplastic Granulocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Dysplastic Erythroid Precursor&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neutrophil with Cytoplasmic Hypogranularity&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neutrophil with Pseudo Chediak-Higashi Granules&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 7q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Monosomy 5&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Granulocytopenia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Thrombocytopenia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Anisocytosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Poikilocytosis&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Anemia&apos;)</deletedAxiom>
<newAxiom>&apos;Myelodysplastic Syndrome with Excess Blasts&apos; EquivalentTo &apos;Myelodysplastic Syndrome&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Bone Marrow Myeloid Stem Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Myeloblast&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts 5-9 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Blasts Under 10 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myeloblasts Under 10 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Megaloblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Micromegakaryocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neutrophil with Pseudo Pelger-Huet Nucleus&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Abnormal Platelet&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Hypolobated Megakaryocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Dysplastic Granulocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Dysplastic Erythroid Precursor&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neutrophil with Cytoplasmic Hypogranularity&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neutrophil with Pseudo Chediak-Higashi Granules&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 7q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Monosomy 5&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Granulocytopenia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Thrombocytopenia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Anisocytosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Poikilocytosis&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Anemia&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65041</classIRI>
<classLabel>Peribulbar Route of Administration</classLabel>
<deletedAxiom>&apos;Peribulbar Route of Administration&apos; SubClassOf &apos;Ophthalmic Route of Administration&apos;</deletedAxiom>
<deletedAxiom>&apos;Peribulbar Route of Administration&apos; SubClassOf &apos;Parenteral Route of Administration&apos;</deletedAxiom>
<newAxiom>&apos;Peribulbar Route of Administration&apos; SubClassOf &apos;Route of Administration&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65114</classIRI>
<classLabel>Suborbital Route of Administration</classLabel>
<deletedAxiom>&apos;Suborbital Route of Administration&apos; SubClassOf &apos;Parenteral Route of Administration&apos;</deletedAxiom>
<deletedAxiom>&apos;Suborbital Route of Administration&apos; SubClassOf &apos;Ophthalmic Route of Administration&apos;</deletedAxiom>
<newAxiom>&apos;Suborbital Route of Administration&apos; SubClassOf &apos;Route of Administration&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C79834</classIRI>
<classLabel>Anti-Her-2-CAR Retroviral Vector-Transduced Autologous Peripheral Blood Lymphocytes</classLabel>
<deletedAxiom>&apos;Anti-Her-2-CAR Retroviral Vector-Transduced Autologous Peripheral Blood Lymphocytes&apos; SubClassOf &apos;HER2-targeting Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156869</classIRI>
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<newAxiom>&apos;Mineral Cutting&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
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<newAxiom>&apos;Autologous iC9-deltaNGFR-CD19CAR-CD3zeta-4-1BB-expressing T-lymphocytes&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
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<classLabel>REPLI-g Pooled DNA</classLabel>
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<classLabel>Sales Representatives, Services</classLabel>
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<classLabel>Secretaries and Administrative Assistants</classLabel>
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<classLabel>Rail Transportation Workers</classLabel>
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<classLabel>Printing Workers</classLabel>
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<classLabel>Supervisors, Personal Care and Service Workers</classLabel>
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<classLabel>Other Construction and Related Workers</classLabel>
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<changedClass>
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<classLabel>Other Healthcare Support Occupations</classLabel>
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<changedClass>
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<classLabel>Other Healthcare Practitioners and Technical Occupations</classLabel>
<deletedAxiom>&apos;Other Healthcare Practitioners and Technical Occupations&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Other Healthcare Practitioners and Technical Occupations&apos; SubClassOf &apos;Healthcare Practitioners and Technical Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122554</classIRI>
<classLabel>Other Protective Service Workers</classLabel>
<deletedAxiom>&apos;Other Protective Service Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Other Protective Service Workers&apos; SubClassOf &apos;Protective Service Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122553</classIRI>
<classLabel>Other Production Occupations</classLabel>
<deletedAxiom>&apos;Other Production Occupations&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Other Production Occupations&apos; SubClassOf &apos;Production Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122552</classIRI>
<classLabel>Other Personal Care and Service Workers</classLabel>
<deletedAxiom>&apos;Other Personal Care and Service Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Other Personal Care and Service Workers&apos; SubClassOf &apos;Personal Care and Service Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122551</classIRI>
<classLabel>Other Office and Administrative Support Workers</classLabel>
<deletedAxiom>&apos;Other Office and Administrative Support Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Other Office and Administrative Support Workers&apos; SubClassOf &apos;Office and Administrative Support Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122557</classIRI>
<classLabel>Other Transportation Workers</classLabel>
<deletedAxiom>&apos;Other Transportation Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Other Transportation Workers&apos; SubClassOf &apos;Transportation and Material Moving Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122556</classIRI>
<classLabel>Other Teachers and Instructors</classLabel>
<deletedAxiom>&apos;Other Teachers and Instructors&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Other Teachers and Instructors&apos; SubClassOf &apos;Teacher&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122555</classIRI>
<classLabel>Other Sales and Related Workers</classLabel>
<deletedAxiom>&apos;Other Sales and Related Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Other Sales and Related Workers&apos; SubClassOf &apos;Sales and Related Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C195502</classIRI>
<classLabel>Marasmic Kwashiorkor</classLabel>
<deletedAxiom>&apos;Marasmic Kwashiorkor&apos; SubClassOf &apos;mCode Non-neoplastic Disease/Finding&apos;</deletedAxiom>
<newAxiom>&apos;Marasmic Kwashiorkor&apos; SubClassOf &apos;Nutritional Marasmus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C195501</classIRI>
<classLabel>Nutritional Marasmus</classLabel>
<deletedAxiom>&apos;Nutritional Marasmus&apos; SubClassOf &apos;mCode Non-neoplastic Disease/Finding&apos;</deletedAxiom>
<newAxiom>&apos;Nutritional Marasmus&apos; SubClassOf &apos;Protein Energy Malnutrition&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122406</classIRI>
<classLabel>Duvortuxizumab</classLabel>
<deletedAxiom>&apos;Duvortuxizumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Duvortuxizumab&apos; SubClassOf &apos;Anti-CD3 Monoclonal Antibody&apos;</newAxiom>
<newAxiom>&apos;Duvortuxizumab&apos; SubClassOf &apos;Anti-CD19 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122418</classIRI>
<classLabel>Advertising, Marketing, Promotions, Public Relations, and Sales Managers</classLabel>
<deletedAxiom>&apos;Advertising, Marketing, Promotions, Public Relations, and Sales Managers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Advertising, Marketing, Promotions, Public Relations, and Sales Managers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122473</classIRI>
<classLabel>Librarians, Curators, and Archivists</classLabel>
<deletedAxiom>&apos;Librarians, Curators, and Archivists&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Librarians, Curators, and Archivists&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122472</classIRI>
<classLabel>Legal Support Workers</classLabel>
<deletedAxiom>&apos;Legal Support Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Legal Support Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122471</classIRI>
<classLabel>Lawyers, Judges, and Related Workers</classLabel>
<deletedAxiom>&apos;Lawyers, Judges, and Related Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Lawyers, Judges, and Related Workers&apos; SubClassOf &apos;Legal Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122466</classIRI>
<classLabel>Health Technologists and Technicians</classLabel>
<deletedAxiom>&apos;Health Technologists and Technicians&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Health Technologists and Technicians&apos; SubClassOf &apos;Healthcare Practitioners and Technical Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122465</classIRI>
<classLabel>Health Diagnosing and Treating Practitioners</classLabel>
<deletedAxiom>&apos;Health Diagnosing and Treating Practitioners&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Health Diagnosing and Treating Practitioners&apos; SubClassOf &apos;Healthcare Practitioners and Technical Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122464</classIRI>
<classLabel>Grounds Maintenance Workers</classLabel>
<deletedAxiom>&apos;Grounds Maintenance Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Grounds Maintenance Workers&apos; SubClassOf &apos;Building and Grounds Clearing and Maintenance Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122463</classIRI>
<classLabel>Funeral Service Workers</classLabel>
<deletedAxiom>&apos;Funeral Service Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Funeral Service Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122469</classIRI>
<classLabel>Law Enforcement Workers</classLabel>
<deletedAxiom>&apos;Law Enforcement Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Law Enforcement Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122468</classIRI>
<classLabel>Information and Record Clerks</classLabel>
<deletedAxiom>&apos;Information and Record Clerks&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Information and Record Clerks&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122467</classIRI>
<classLabel>Helpers, Construction Trades</classLabel>
<deletedAxiom>&apos;Helpers, Construction Trades&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Helpers, Construction Trades&apos; SubClassOf &apos;Construction Trades Workers&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122480</classIRI>
<classLabel>Mathematical Science Occupations</classLabel>
<deletedAxiom>&apos;Mathematical Science Occupations&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Mathematical Science Occupations&apos; SubClassOf &apos;Computer and Mathematical Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122484</classIRI>
<classLabel>Military Officer Special and Tactical Operations Leaders and Managers</classLabel>
<deletedAxiom>&apos;Military Officer Special and Tactical Operations Leaders and Managers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Military Officer Special and Tactical Operations Leaders and Managers&apos; SubClassOf &apos;Military Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122483</classIRI>
<classLabel>Metal Workers and Plastic Workers</classLabel>
<deletedAxiom>&apos;Metal Workers and Plastic Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Metal Workers and Plastic Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122482</classIRI>
<classLabel>Media and Communication Workers</classLabel>
<deletedAxiom>&apos;Media and Communication Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Media and Communication Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122481</classIRI>
<classLabel>Media and Communication Equipment Workers</classLabel>
<deletedAxiom>&apos;Media and Communication Equipment Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Media and Communication Equipment Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122477</classIRI>
<classLabel>Material Recording, Scheduling, Dispatching, and Distributing Workers</classLabel>
<deletedAxiom>&apos;Material Recording, Scheduling, Dispatching, and Distributing Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Material Recording, Scheduling, Dispatching, and Distributing Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122476</classIRI>
<classLabel>Material Moving Workers</classLabel>
<deletedAxiom>&apos;Material Moving Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Material Moving Workers&apos; SubClassOf &apos;Transportation and Material Moving Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122475</classIRI>
<classLabel>Life, Physical, and Social Science Technicians</classLabel>
<deletedAxiom>&apos;Life, Physical, and Social Science Technicians&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Life, Physical, and Social Science Technicians&apos; SubClassOf &apos;Life, Physical, and Social Science Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122474</classIRI>
<classLabel>Life Scientists</classLabel>
<deletedAxiom>&apos;Life Scientists&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Life Scientists&apos; SubClassOf &apos;Life, Physical, and Social Science Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122488</classIRI>
<classLabel>Occupational and Physical Therapist Assistants and Aides</classLabel>
<deletedAxiom>&apos;Occupational and Physical Therapist Assistants and Aides&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Occupational and Physical Therapist Assistants and Aides&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122487</classIRI>
<classLabel>Nursing, Psychiatric, and Home Health Aides</classLabel>
<deletedAxiom>&apos;Nursing, Psychiatric, and Home Health Aides&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Nursing, Psychiatric, and Home Health Aides&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122486</classIRI>
<classLabel>Motor Vehicle Operators</classLabel>
<deletedAxiom>&apos;Motor Vehicle Operators&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Motor Vehicle Operators&apos; SubClassOf &apos;Transportation and Material Moving Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122485</classIRI>
<classLabel>Military Enlisted Tactical Operations and Air/Weapons Specialists and Crew Members</classLabel>
<deletedAxiom>&apos;Military Enlisted Tactical Operations and Air/Weapons Specialists and Crew Members&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Military Enlisted Tactical Operations and Air/Weapons Specialists and Crew Members&apos; SubClassOf &apos;Military Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122489</classIRI>
<classLabel>Operations Specialties Managers</classLabel>
<deletedAxiom>&apos;Operations Specialties Managers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Operations Specialties Managers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122499</classIRI>
<classLabel>Postsecondary Teachers</classLabel>
<deletedAxiom>&apos;Postsecondary Teachers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Postsecondary Teachers&apos; SubClassOf &apos;Teacher&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122498</classIRI>
<classLabel>Plant and System Operators</classLabel>
<deletedAxiom>&apos;Plant and System Operators&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Plant and System Operators&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122497</classIRI>
<classLabel>Physical Scientists</classLabel>
<deletedAxiom>&apos;Physical Scientists&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Physical Scientists&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122496</classIRI>
<classLabel>Personal Appearance Workers</classLabel>
<deletedAxiom>&apos;Personal Appearance Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Personal Appearance Workers&apos; SubClassOf &apos;Personal Care and Service Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122429</classIRI>
<classLabel>Assemblers and Fabricators</classLabel>
<deletedAxiom>&apos;Assemblers and Fabricators&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Assemblers and Fabricators&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122428</classIRI>
<classLabel>Art and Design Workers</classLabel>
<deletedAxiom>&apos;Art and Design Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Art and Design Workers&apos; SubClassOf &apos;Arts, Design, Entertainment, Sports and Media Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Air Transportation Workers</classLabel>
<deletedAxiom>&apos;Air Transportation Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Air Transportation Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122421</classIRI>
<classLabel>Agricultural Workers</classLabel>
<deletedAxiom>&apos;Agricultural Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Agricultural Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122424</classIRI>
<classLabel>Architects, Surveyors, and Cartographers</classLabel>
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<newAxiom>&apos;Architects, Surveyors, and Cartographers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122423</classIRI>
<classLabel>Animal Care and Service Workers</classLabel>
<deletedAxiom>&apos;Animal Care and Service Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Animal Care and Service Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122440</classIRI>
<classLabel>Cooks and Food Preparation Workers</classLabel>
<deletedAxiom>&apos;Cooks and Food Preparation Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Cooks and Food Preparation Workers&apos; SubClassOf &apos;Food Preparation and Serving, Related Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122433</classIRI>
<classLabel>Communications Equipment Operators</classLabel>
<deletedAxiom>&apos;Communications Equipment Operators&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Communications Equipment Operators&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122432</classIRI>
<classLabel>Business Operations Specialists</classLabel>
<deletedAxiom>&apos;Business Operations Specialists&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Business Operations Specialists&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122431</classIRI>
<classLabel>Building Cleaning and Pest Control Workers</classLabel>
<deletedAxiom>&apos;Building Cleaning and Pest Control Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Building Cleaning and Pest Control Workers&apos; SubClassOf &apos;Building and Grounds Clearing and Maintenance Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122434</classIRI>
<classLabel>Computer Specialists</classLabel>
<deletedAxiom>&apos;Computer Specialists&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Computer Specialists&apos; SubClassOf &apos;Computer and Mathematical Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122451</classIRI>
<classLabel>Financial Clerks</classLabel>
<deletedAxiom>&apos;Financial Clerks&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Financial Clerks&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122449</classIRI>
<classLabel>Entertainment Attendants and Related Workers</classLabel>
<deletedAxiom>&apos;Entertainment Attendants and Related Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Entertainment Attendants and Related Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122442</classIRI>
<classLabel>Drafters, Engineering, and Mapping Technicians</classLabel>
<deletedAxiom>&apos;Drafters, Engineering, and Mapping Technicians&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Drafters, Engineering, and Mapping Technicians&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122441</classIRI>
<classLabel>Counselors, Social Workers, and Other Community and Social Service Specialists</classLabel>
<deletedAxiom>&apos;Counselors, Social Workers, and Other Community and Social Service Specialists&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Counselors, Social Workers, and Other Community and Social Service Specialists&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122448</classIRI>
<classLabel>Entertainers and Performers, Sports and Related Workers</classLabel>
<deletedAxiom>&apos;Entertainers and Performers, Sports and Related Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Entertainers and Performers, Sports and Related Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122447</classIRI>
<classLabel>Engineers</classLabel>
<deletedAxiom>&apos;Engineers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Engineers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122446</classIRI>
<classLabel>Electrical and Electronic Equipment Mechanics, Installers, and Repairers</classLabel>
<deletedAxiom>&apos;Electrical and Electronic Equipment Mechanics, Installers, and Repairers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Electrical and Electronic Equipment Mechanics, Installers, and Repairers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122461</classIRI>
<classLabel>Food Processing Workers</classLabel>
<deletedAxiom>&apos;Food Processing Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Food Processing Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122460</classIRI>
<classLabel>Food and Beverage Serving Workers</classLabel>
<deletedAxiom>&apos;Food and Beverage Serving Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Food and Beverage Serving Workers&apos; SubClassOf &apos;Food Preparation and Serving, Related Occupations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122455</classIRI>
<classLabel>First-Line Protective Service Worker Supervisors and Managers</classLabel>
<deletedAxiom>&apos;First-Line Protective Service Worker Supervisors and Managers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;First-Line Protective Service Worker Supervisors and Managers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122454</classIRI>
<classLabel>First-Line Enlisted Military Supervisor and Managers</classLabel>
<deletedAxiom>&apos;First-Line Enlisted Military Supervisor and Managers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;First-Line Enlisted Military Supervisor and Managers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122453</classIRI>
<classLabel>Fire Fighting and Prevention Workers</classLabel>
<deletedAxiom>&apos;Fire Fighting and Prevention Workers&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Fire Fighting and Prevention Workers&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122452</classIRI>
<classLabel>Financial Specialists</classLabel>
<deletedAxiom>&apos;Financial Specialists&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Financial Specialists&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C51959</classIRI>
<classLabel>Attorney</classLabel>
<deletedAxiom>&apos;Attorney&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Attorney&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C51960</classIRI>
<classLabel>Biomedical Engineer</classLabel>
<deletedAxiom>&apos;Biomedical Engineer&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Biomedical Engineer&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C161838</classIRI>
<classLabel>Hepatocellular Malignant Neoplasm, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Hepatocellular Malignant Neoplasm, Not Otherwise Specified&apos; EquivalentTo &apos;Hepatoblastoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Hepatocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Adenocarcinoma Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Morphologic Overlap&apos;)</deletedAxiom>
<newAxiom>&apos;Hepatocellular Malignant Neoplasm, Not Otherwise Specified&apos; EquivalentTo &apos;Hepatoblastoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Hepatocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Adenocarcinoma Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Morphologic Overlap&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C85488</classIRI>
<classLabel>Service Occupation</classLabel>
<deletedAxiom>&apos;Service Occupation&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Service Occupation&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C85487</classIRI>
<classLabel>Equipment Operator</classLabel>
<deletedAxiom>&apos;Equipment Operator&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Equipment Operator&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C71009</classIRI>
<classLabel>Coltuximab Ravtansine</classLabel>
<deletedAxiom>&apos;Coltuximab Ravtansine&apos; SubClassOf &apos;Anti-CD19 Immunotoxins&apos;</deletedAxiom>
<newAxiom>&apos;Coltuximab Ravtansine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198859</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162620</classIRI>
<classLabel>Autologous Anti-CD19/CD22 CAR T-cells AUTO3</classLabel>
<newAxiom>&apos;Autologous Anti-CD19/CD22 CAR T-cells AUTO3&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162676</classIRI>
<classLabel>Elzovantinib</classLabel>
<newAxiom>&apos;Elzovantinib&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198646</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C71337</classIRI>
<classLabel>Certified Physician Assistant</classLabel>
<deletedAxiom>&apos;Certified Physician Assistant&apos; SubClassOf &apos;Medical Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Certified Physician Assistant&apos; SubClassOf &apos;Physician Assistant&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103934</classIRI>
<classLabel>Welding Occupations</classLabel>
<deletedAxiom>&apos;Welding Occupations&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Welding Occupations&apos; SubClassOf &apos;Trades, Transport, or Construction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103933</classIRI>
<classLabel>Automotive Occupations</classLabel>
<deletedAxiom>&apos;Automotive Occupations&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Automotive Occupations&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176568</classIRI>
<classLabel>Autologous Anti-CD22 CAR-expressing T-cells SCRI-CAR22v2</classLabel>
<deletedAxiom>&apos;Autologous Anti-CD22 CAR-expressing T-cells SCRI-CAR22v2&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Anti-CD22 CAR-expressing T-cells SCRI-CAR22v2&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142834</classIRI>
<classLabel>Autologous CD19/CD22 Chimeric Antigen Receptor T-cells CT120</classLabel>
<newAxiom>&apos;Autologous CD19/CD22 Chimeric Antigen Receptor T-cells CT120&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91091</classIRI>
<classLabel>Anti-HER2-CAR Autologous CMV-Specific Cytotoxic T-Lymphocytes</classLabel>
<deletedAxiom>&apos;Anti-HER2-CAR Autologous CMV-Specific Cytotoxic T-Lymphocytes&apos; SubClassOf &apos;HER2-targeting Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181943</classIRI>
<classLabel>Autologous Anti-CD19/CD20 CAR-T Cells KITE-363</classLabel>
<newAxiom>&apos;Autologous Anti-CD19/CD20 CAR-T Cells KITE-363&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181902</classIRI>
<classLabel>Vulvar Squamous Cell Carcinoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Vulvar Squamous Cell Carcinoma, Not Otherwise Specified&apos; EquivalentTo &apos;Vulvar Squamous Cell Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;p16 Immunohistochemistry or HPV Testing Status Unknown&apos;)</deletedAxiom>
<newAxiom>&apos;Vulvar Squamous Cell Carcinoma, Not Otherwise Specified&apos; EquivalentTo &apos;Vulvar Squamous Cell Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;p16 Immunohistochemistry or HPV Testing Status Unknown&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180596</classIRI>
<classLabel>Zamtocabtagene Autoleucel</classLabel>
<newAxiom>&apos;Zamtocabtagene Autoleucel&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180584</classIRI>
<classLabel>Anbalcabtagene Autoleucel</classLabel>
<deletedAxiom>&apos;Anbalcabtagene Autoleucel&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Anbalcabtagene Autoleucel&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27038</classIRI>
<classLabel>Hypereosinophilic Syndrome</classLabel>
<deletedAxiom>&apos;Hypereosinophilic Syndrome&apos; EquivalentTo &apos;Syndrome&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Eosinophilia&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Eosinophilic Endomyocardial Disease&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Monoclonal Eosinophils Present&apos;)</deletedAxiom>
<newAxiom>&apos;Hypereosinophilic Syndrome&apos; EquivalentTo &apos;Syndrome&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Eosinophilia&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Monoclonal Eosinophils Present&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121804</classIRI>
<classLabel>Undifferentiated Sarcoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Undifferentiated Sarcoma, Not Otherwise Specified&apos; EquivalentTo &apos;Undifferentiated Soft Tissue Sarcoma&apos; and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Epithelioid Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Primitive Mesenchymal Round to Oval Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Spindle Cell&apos;)</deletedAxiom>
<newAxiom>&apos;Undifferentiated Sarcoma, Not Otherwise Specified&apos; EquivalentTo &apos;Undifferentiated Soft Tissue Sarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Epithelioid Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Primitive Mesenchymal Round to Oval Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Malignant Spindle Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C194975</classIRI>
<classLabel>Hematopoietic and Lymphoid System Neoplasm</classLabel>
<deletedAxiom>&apos;Hematopoietic and Lymphoid System Neoplasm&apos; SubClassOf &apos;mCode Neoplastic Disease/Finding&apos;</deletedAxiom>
<newAxiom>&apos;Hematopoietic and Lymphoid System Neoplasm&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C194972</classIRI>
<classLabel>Pineal Region Neoplasm</classLabel>
<deletedAxiom>&apos;Pineal Region Neoplasm&apos; SubClassOf &apos;mCode Neoplastic Disease/Finding&apos;</deletedAxiom>
<newAxiom>&apos;Pineal Region Neoplasm&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C194970</classIRI>
<classLabel>Pituitary Gland Neoplasm</classLabel>
<deletedAxiom>&apos;Pituitary Gland Neoplasm&apos; SubClassOf &apos;mCode Neoplastic Disease/Finding&apos;</deletedAxiom>
<newAxiom>&apos;Pituitary Gland Neoplasm&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C194969</classIRI>
<classLabel>Central Nervous System Neoplasm</classLabel>
<deletedAxiom>&apos;Central Nervous System Neoplasm&apos; SubClassOf &apos;mCode Neoplastic Disease/Finding&apos;</deletedAxiom>
<newAxiom>&apos;Central Nervous System Neoplasm&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C194967</classIRI>
<classLabel>Spinal Cord Neoplasm</classLabel>
<deletedAxiom>&apos;Spinal Cord Neoplasm&apos; SubClassOf &apos;mCode Neoplastic Disease/Finding&apos;</deletedAxiom>
<newAxiom>&apos;Spinal Cord Neoplasm&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C194966</classIRI>
<classLabel>Cranial Nerve Neoplasm</classLabel>
<deletedAxiom>&apos;Cranial Nerve Neoplasm&apos; SubClassOf &apos;mCode Neoplastic Disease/Finding&apos;</deletedAxiom>
<newAxiom>&apos;Cranial Nerve Neoplasm&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C194964</classIRI>
<classLabel>Infratentorial Neoplasm</classLabel>
<deletedAxiom>&apos;Infratentorial Neoplasm&apos; SubClassOf &apos;mCode Neoplastic Disease/Finding&apos;</deletedAxiom>
<newAxiom>&apos;Infratentorial Neoplasm&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C194963</classIRI>
<classLabel>Supratentorial Neoplasm</classLabel>
<deletedAxiom>&apos;Supratentorial Neoplasm&apos; SubClassOf &apos;mCode Neoplastic Disease/Finding&apos;</deletedAxiom>
<newAxiom>&apos;Supratentorial Neoplasm&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C194962</classIRI>
<classLabel>Meningeal Neoplasm</classLabel>
<deletedAxiom>&apos;Meningeal Neoplasm&apos; SubClassOf &apos;mCode Neoplastic Disease/Finding&apos;</deletedAxiom>
<newAxiom>&apos;Meningeal Neoplasm&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27262</classIRI>
<classLabel>Myelodysplastic/Myeloproliferative Neoplasm</classLabel>
<deletedAxiom>&apos;Myelodysplastic/Myeloproliferative Neoplasm&apos; EquivalentTo &apos;Malignant Bone Marrow Neoplasm&apos; and &apos;Myeloid Neoplasm&apos; and ((&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(9;22)(q34.1;q11.2)&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;Philadelphia Chromosome&apos;)) and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Marrow&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Blasts Under 20 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Blasts Under 20 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Splenomegaly&apos;)</deletedAxiom>
<newAxiom>&apos;Myelodysplastic/Myeloproliferative Neoplasm&apos; EquivalentTo &apos;Malignant Bone Marrow Neoplasm&apos; and &apos;Myeloid Neoplasm&apos; and ((&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(9;22)(q34.1;q11.2)&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;Philadelphia Chromosome&apos;)) and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Marrow&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Blasts Under 20 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Blasts Under 20 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Toxic Neutrophil&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Extramedullary Hematopoiesis&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27350</classIRI>
<classLabel>Myeloproliferative Neoplasm, Unclassifiable</classLabel>
<deletedAxiom>&apos;Myeloproliferative Neoplasm, Unclassifiable&apos; EquivalentTo &apos;Myeloproliferative Neoplasm&apos; and ((&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(9;22)(q34.1;q11.2)&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;Philadelphia Chromosome&apos;)) and (&apos;Disease_May_Have_Normal_Cell_Origin&apos; some &apos;Pluripotent Bone Marrow Stem Cell&apos;) and (&apos;Disease_May_Have_Normal_Cell_Origin&apos; some &apos;Multipotent Bone Marrow Stem Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cytopenia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Erythroid Hyperplasia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Megakaryocytes Increased in Bone Marrow&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Leukocytosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Thrombocytosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hypercellular Bone Marrow&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Chronic Clinical Course&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Granulocytes Increased in Bone Marrow&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Anemia&apos;)</deletedAxiom>
<newAxiom>&apos;Myeloproliferative Neoplasm, Unclassifiable&apos; EquivalentTo &apos;Myeloproliferative Neoplasm&apos; and ((&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(9;22)(q34.1;q11.2)&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;Philadelphia Chromosome&apos;)) and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198590) and (&apos;Disease_May_Have_Normal_Cell_Origin&apos; some &apos;Pluripotent Bone Marrow Stem Cell&apos;) and (&apos;Disease_May_Have_Normal_Cell_Origin&apos; some &apos;Multipotent Bone Marrow Stem Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cytopenia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Erythroid Hyperplasia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Megakaryocytes Increased in Bone Marrow&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Leukocytosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Thrombocytosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hypercellular Bone Marrow&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Chronic Clinical Course&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Granulocytes Increased in Bone Marrow&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Anemia&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;MPL Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CALR Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;JAK2 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C194708</classIRI>
<classLabel>Peripheral T-Cell Lymphoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; SubClassOf &apos;mCode Neoplastic Disease/Finding&apos;</deletedAxiom>
<newAxiom>&apos;Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C52663</classIRI>
<classLabel>Office Manager</classLabel>
<deletedAxiom>&apos;Office Manager&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Office Manager&apos; SubClassOf &apos;Manager&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27753</classIRI>
<classLabel>Acute Myeloid Leukemia Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Acute Myeloid Leukemia Not Otherwise Specified&apos; EquivalentTo &apos;Acute Myeloid Leukemia&apos; and (&apos;Disease_Excludes_Finding&apos; some &apos;Bone Marrow Dysplasia Present in 50 Percent or More of the Cells of Two Cell Lines&apos;)</deletedAxiom>
<newAxiom>&apos;Acute Myeloid Leukemia Not Otherwise Specified&apos; EquivalentTo &apos;Acute Myeloid Leukemia&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Blasts 20 Percent or More of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Bone Marrow Dysplasia Present in 50 Percent or More of the Cells of Two Cell Lines&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160798</classIRI>
<classLabel>Carfilzomib Regimen</classLabel>
<deletedAxiom>&apos;Carfilzomib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Non-Hodgkin Lymphoma&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160772</classIRI>
<classLabel>Anti-PD-L1/CD137 Bispecific Antibody MCLA-145</classLabel>
<deletedAxiom>&apos;Anti-PD-L1/CD137 Bispecific Antibody MCLA-145&apos; SubClassOf &apos;CD137 Agonist&apos;</deletedAxiom>
<newAxiom>&apos;Anti-PD-L1/CD137 Bispecific Antibody MCLA-145&apos; SubClassOf &apos;Anti-CD137 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C169106</classIRI>
<classLabel>Environmental DNA</classLabel>
<deletedAxiom>&apos;Environmental DNA&apos; SubClassOf &apos;Biospecimen&apos;</deletedAxiom>
<newAxiom>&apos;Environmental DNA&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198567</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160777</classIRI>
<classLabel>Autologous Anti-CD19/Anti-CD20-CAR-CD28-4-1BB-CD3zeta-EGFRt+-expressing Tn/mem Cells</classLabel>
<newAxiom>&apos;Autologous Anti-CD19/Anti-CD20-CAR-CD28-4-1BB-CD3zeta-EGFRt+-expressing Tn/mem Cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27780</classIRI>
<classLabel>Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable</classLabel>
<deletedAxiom>&apos;Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable&apos; EquivalentTo &apos;Myelodysplastic/Myeloproliferative Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Hypercellular Bone Marrow&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Giant Platelet&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Dysplastic Neutrophil&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Large Megakaryocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Dysplastic Megakaryocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Dysplastic Granulocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Dysplastic Erythroid Precursor&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Leukocytosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Thrombocytosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Ring Sideroblasts Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Bone Marrow Dysplasia Present&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Anemia&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NRAS Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable&apos; EquivalentTo &apos;Myelodysplastic/Myeloproliferative Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Cytopenia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Thrombocytosis&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198558)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27892</classIRI>
<classLabel>Unclassified Renal Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Unclassified Renal Cell Carcinoma&apos; EquivalentTo &apos;Renal Cell Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Mixed Cellular Population&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Mixture of Morphologic Patterns&apos;)</deletedAxiom>
<newAxiom>&apos;Unclassified Renal Cell Carcinoma&apos; EquivalentTo &apos;Renal Cell Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198590) and (&apos;Disease_May_Have_Finding&apos; some &apos;Mixed Cellular Population&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Mixture of Morphologic Patterns&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160965</classIRI>
<classLabel>Cisplatin/Fluorouracil/Pembrolizumab Regimen</classLabel>
<newAxiom>&apos;Cisplatin/Fluorouracil/Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Esophageal Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Cisplatin/Fluorouracil/Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Gastric Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160565</classIRI>
<classLabel>FLOT Regimen</classLabel>
<newAxiom>&apos;FLOT Regimen&apos; SubClassOf &apos;Regimen Used to Treat Esophageal Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160545</classIRI>
<classLabel>BDR Regimen</classLabel>
<newAxiom>&apos;BDR Regimen&apos; SubClassOf &apos;Regimen Used to Treat Castleman disease&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C169052</classIRI>
<classLabel>Ensomafusp Alfa</classLabel>
<deletedAxiom>&apos;Ensomafusp Alfa&apos; SubClassOf &apos;Immunotherapeutic Agent&apos;</deletedAxiom>
<newAxiom>&apos;Ensomafusp Alfa&apos; SubClassOf &apos;CD137 Agonist&apos;</newAxiom>
<newAxiom>&apos;Ensomafusp Alfa&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198634</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C194073</classIRI>
<classLabel>Meckel Diverticulum Neuroendocrine Tumor G1</classLabel>
<deletedAxiom>&apos;Meckel Diverticulum Neuroendocrine Tumor G1&apos; SubClassOf &apos;mCode Neoplastic Disease/Finding&apos;</deletedAxiom>
<newAxiom>&apos;Meckel Diverticulum Neuroendocrine Tumor G1&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C86557</classIRI>
<classLabel>Interpreter</classLabel>
<deletedAxiom>&apos;Interpreter&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Interpreter&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160109</classIRI>
<classLabel>Pemetrexed Regimen</classLabel>
<newAxiom>&apos;Pemetrexed Regimen&apos; SubClassOf &apos;Regimen Used to Treat Central Nervous System Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160108</classIRI>
<classLabel>Pembrolizumab Regimen</classLabel>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Neuroendocrine and Adrenal Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Ovarian Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Prostate Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Hodgkin Lymphoma&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Esophageal Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Pancreatic Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Small Cell Lung Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Gastric Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Cervical Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Peritoneal Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Merkel Cell Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Germ Cell Tumor&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Fallopian Tube Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Thyroid Cancer&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Skin Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Breast Carcinoma&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Head and Neck Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Renal Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Thymus Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Malignant Soft Tissue Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Pembrolizumab Regimen&apos; SubClassOf &apos;Regimen Used to Treat Vulvar Cancer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160106</classIRI>
<classLabel>Peginterferon Alfa-2a Regimen</classLabel>
<newAxiom>&apos;Peginterferon Alfa-2a Regimen&apos; SubClassOf &apos;Regimen Used to Treat Leukemia&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160111</classIRI>
<classLabel>Ponatinib Regimen</classLabel>
<newAxiom>&apos;Ponatinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Lymphocytic Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Ponatinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Myeloid Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Ponatinib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Acute Lymphoblastic Leukemia&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160118</classIRI>
<classLabel>Sorafenib Regimen</classLabel>
<newAxiom>&apos;Sorafenib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Acute Myeloid Leukemia&apos;</newAxiom>
<newAxiom>&apos;Sorafenib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Myeloid Neoplasm&apos;</newAxiom>
<newAxiom>&apos;Sorafenib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Lymphocytic Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C86928</classIRI>
<classLabel>Translator</classLabel>
<deletedAxiom>&apos;Translator&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Translator&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175876</classIRI>
<classLabel>Vimseltinib</classLabel>
<deletedAxiom>&apos;Vimseltinib&apos; SubClassOf &apos;Tyrosine Kinase Inhibitor&apos;</deletedAxiom>
<deletedAxiom>&apos;Vimseltinib&apos; SubClassOf &apos;Antineoplastic Enzyme Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Vimseltinib&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198646</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136273</classIRI>
<classLabel>Dexamethasone/Ixazomib Regimen</classLabel>
<newAxiom>&apos;Dexamethasone/Ixazomib Regimen&apos; SubClassOf &apos;Regimen Used to Treat Primary Amyloidosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136272</classIRI>
<classLabel>IRd Regimen</classLabel>
<newAxiom>&apos;IRd Regimen&apos; SubClassOf &apos;Regimen Used to Treat Primary Amyloidosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102877</classIRI>
<classLabel>Olinvacimab</classLabel>
<deletedAxiom>&apos;Olinvacimab&apos; SubClassOf &apos;Anti-VEGF Monoclonal Antibody&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102873</classIRI>
<classLabel>Teacher</classLabel>
<deletedAxiom>&apos;Teacher&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Teacher&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102869</classIRI>
<classLabel>International Neuroblastoma Response Criteria</classLabel>
<deletedAxiom>&apos;International Neuroblastoma Response Criteria&apos; SubClassOf &apos;Research or Clinical Assessment Tool&apos;</deletedAxiom>
<newAxiom>&apos;International Neuroblastoma Response Criteria&apos; SubClassOf &apos;Tumor Response System&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175738</classIRI>
<classLabel>Afamitresgene Autoleucel</classLabel>
<newAxiom>&apos;Afamitresgene Autoleucel&apos; SubClassOf &apos;T-cell Receptor-engineered T-cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175452</classIRI>
<classLabel>Autologous PD1-knockout CD19-specific CAR T Cells</classLabel>
<deletedAxiom>&apos;Autologous PD1-knockout CD19-specific CAR T Cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous PD1-knockout CD19-specific CAR T Cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175460</classIRI>
<classLabel>FGFR/CSF-1R Inhibitor 3D185</classLabel>
<newAxiom>&apos;FGFR/CSF-1R Inhibitor 3D185&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198646</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9432</classIRI>
<classLabel>Malignant Pleural Effusion</classLabel>
<newAxiom>&apos;Malignant Pleural Effusion&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198611</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9286</classIRI>
<classLabel>Indolent Systemic Mastocytosis</classLabel>
<deletedAxiom>&apos;Indolent Systemic Mastocytosis&apos; EquivalentTo &apos;Systemic Mastocytosis&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Indolent Clinical Course&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cutaneous Involvement&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Cytopenia&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Pathologic Fracture&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Portal Hypertension&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Malabsorption Syndrome&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Hypersplenism&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Lytic Bone Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Indolent Systemic Mastocytosis&apos; EquivalentTo &apos;Systemic Mastocytosis&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Indolent Clinical Course&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Cytopenia&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Pathologic Fracture&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Portal Hypertension&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Malabsorption Syndrome&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Hypersplenism&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Lytic Bone Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9233</classIRI>
<classLabel>Juvenile Myelomonocytic Leukemia</classLabel>
<deletedAxiom>&apos;Juvenile Myelomonocytic Leukemia&apos; EquivalentTo &apos;Myelodysplastic/Myeloproliferative Neoplasm&apos; and ((&apos;Disease_May_Have_Finding&apos; some &apos;Cafe Au Lait Spot&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Neurofibromatosis Type 1&apos;)) and (&apos;Disease_Has_Finding&apos; some &apos;Monocytosis&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Leukocytosis&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Hypercellular Bone Marrow&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Immature Granulocytes in Peripheral Blood Increased&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Monosomy 7&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fatigue&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Thrombocytopenia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Nucleated Red Blood Cells Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Polyclonal Hypergammaglobulinemia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemoglobin F Increased&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Rash&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Elevated Serum Lysozyme&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Absence of Bone Marrow Dysplasia&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Bronchitis&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Noonan Syndrome&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Anemia&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Auer Rods Present&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NRAS Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PTPN11 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Juvenile Myelomonocytic Leukemia&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198663 and &apos;Childhood Malignant Neoplasm&apos; and &apos;Childhood Hematopoietic and Lymphoid Cell Neoplasm&apos; and ((&apos;Disease_May_Have_Finding&apos; some &apos;Cafe Au Lait Spot&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Neurofibromatosis Type 1&apos;)) and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198660) and (&apos;Disease_Has_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Monocytosis&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Leukocytosis&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Hypercellular Bone Marrow&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Immature Granulocytes in Peripheral Blood Increased&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Blasts Under 20 Percent of Peripheral Blood White Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Blasts Under 20 Percent of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Monosomy 7&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fatigue&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Thrombocytopenia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Nucleated Red Blood Cells Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Polyclonal Hypergammaglobulinemia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemoglobin F Increased&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Rash&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Elevated Serum Lysozyme&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Bronchitis&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Anemia&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCR-ABL1 Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Auer Rods Present&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;RRAS Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KRAS Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NRAS Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PTPN11 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189688</classIRI>
<classLabel>Circulating Cell-Free Human Papillomavirus DNA</classLabel>
<newAxiom>&apos;Circulating Cell-Free Human Papillomavirus DNA&apos; SubClassOf &apos;Circulating Cell-Free DNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67061</classIRI>
<classLabel>Deglycosylated Ricin A Chain-Conjugated Anti-CD19/Anti-CD22 Immunotoxins</classLabel>
<newAxiom>&apos;Deglycosylated Ricin A Chain-Conjugated Anti-CD19/Anti-CD22 Immunotoxins&apos; SubClassOf &apos;Anti-CD19 Immunotoxins&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189702</classIRI>
<classLabel>Allogeneic Anti-CD19/CD22 CAR-BBz T-cells</classLabel>
<newAxiom>&apos;Allogeneic Anti-CD19/CD22 CAR-BBz T-cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C33910</classIRI>
<classLabel>DNA Replication Licensing Factor MCM5</classLabel>
<deletedAxiom>&apos;DNA Replication Licensing Factor MCM5&apos; EquivalentTo &apos;Licensing Factor&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cell Cycle Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;CDK Regulation Pathway&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;DNA Binding Protein&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;MCM Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcription&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Replication Licensing&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Replication Initiation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;MCM5 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;DNA Replication Licensing Factor MCM5&apos; EquivalentTo &apos;DNA Helicase&apos; and &apos;Licensing Factor&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cell Cycle Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;CDK Regulation Pathway&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;DNA Binding Protein&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;MCM Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcription&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Replication Licensing&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Replication Initiation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;MCM5 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C155897</classIRI>
<classLabel>Autologous Anti-CD19CAR-HER2t/CD22CAR-EGFRt-expressing T-cells</classLabel>
<newAxiom>&apos;Autologous Anti-CD19CAR-HER2t/CD22CAR-EGFRt-expressing T-cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180839</classIRI>
<classLabel>Cervical Squamous Cell Carcinoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Cervical Squamous Cell Carcinoma, Not Otherwise Specified&apos; EquivalentTo &apos;Cervical Squamous Cell Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;p16 Immunohistochemistry or HPV Testing Status Unknown&apos;)</deletedAxiom>
<newAxiom>&apos;Cervical Squamous Cell Carcinoma, Not Otherwise Specified&apos; EquivalentTo &apos;Cervical Squamous Cell Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Unclassifiable/Not Further Specified Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;p16 Immunohistochemistry or HPV Testing Status Unknown&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67494</classIRI>
<classLabel>FLT3 Internal Tandem Duplication</classLabel>
<deletedAxiom>&apos;FLT3 Internal Tandem Duplication&apos; SubClassOf &apos;Molecular_Abnormality_Involves_Gene&apos; some &apos;FLT3 Gene&apos;</deletedAxiom>
<deletedAxiom>&apos;FLT3 Internal Tandem Duplication&apos; SubClassOf &apos;Chromosome 13q Abnormality&apos;</deletedAxiom>
<deletedAxiom>&apos;FLT3 Internal Tandem Duplication&apos; SubClassOf &apos;Receptor Tyrosine Kinase Gene Rearrangement&apos;</deletedAxiom>
<newAxiom>&apos;FLT3 Internal Tandem Duplication&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198560</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C155697</classIRI>
<classLabel>Counselor</classLabel>
<deletedAxiom>&apos;Counselor&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Counselor&apos; SubClassOf &apos;Counselors, Social Workers, and Other Community and Social Service Specialists&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C141146</classIRI>
<classLabel>Anti-TIM-3 Monoclonal Antibody</classLabel>
<newAxiom>&apos;Anti-TIM-3 Monoclonal Antibody&apos; SubClassOf &apos;Monoclonal Antibody&apos;</newAxiom>
<newAxiom>&apos;Anti-TIM-3 Monoclonal Antibody&apos; SubClassOf &apos;Immune Checkpoint Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C92632</classIRI>
<classLabel>Schizotypal Personality Disorder</classLabel>
<newAxiom>&apos;Schizotypal Personality Disorder&apos; SubClassOf &apos;Schizophrenia and Other Psychotic Disorders&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28181</classIRI>
<classLabel>Psychologist</classLabel>
<deletedAxiom>&apos;Psychologist&apos; SubClassOf &apos;Miscellaneous Occupation&apos;</deletedAxiom>
<newAxiom>&apos;Psychologist&apos; SubClassOf &apos;Occupation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189059</classIRI>
<classLabel>Anti-CD19/Anti-CD79b 4SCAR-expressing Bispecific T-cells</classLabel>
<newAxiom>&apos;Anti-CD19/Anti-CD79b 4SCAR-expressing Bispecific T-cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189058</classIRI>
<classLabel>Anti-CD19/Anti-CD70 4SCAR-expressing Bispecific T-cells</classLabel>
<newAxiom>&apos;Anti-CD19/Anti-CD70 4SCAR-expressing Bispecific T-cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198561</classIRI>
<classLabel>t(12;13)(p13.2;q12.2)</classLabel>
<newAxiom>'t(12;13)(p13.2;q12.2)' SubClassOf 'ETV6 Gene Rearrangement'</newAxiom>
<newAxiom>'t(12;13)(p13.2;q12.2)' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'ETV6/FLT3 Fusion Gene'</newAxiom>
<newAxiom>'t(12;13)(p13.2;q12.2)' SubClassOf 'FLT3 Gene Rearrangement'</newAxiom>
<newAxiom>'t(12;13)(p13.2;q12.2)' SubClassOf 'Chromosomal Translocation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198562</classIRI>
<classLabel>ETV6/FLT3 Fusion Gene</classLabel>
<newAxiom>'ETV6/FLT3 Fusion Gene' SubClassOf 'Fusion Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198563</classIRI>
<classLabel>ETV6-FLT3 Fusion Protein Expression</classLabel>
<newAxiom>'ETV6-FLT3 Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'ETV6 Gene'</newAxiom>
<newAxiom>'ETV6-FLT3 Fusion Protein Expression' SubClassOf 'Fusion Protein Expression'</newAxiom>
<newAxiom>'ETV6-FLT3 Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'FLT3 Gene'</newAxiom>
<newAxiom>'ETV6-FLT3 Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'ETV6/FLT3 Fusion Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198564</classIRI>
<classLabel>ETV6-ABL1 Fusion Expression</classLabel>
<newAxiom>'ETV6-ABL1 Fusion Expression' SubClassOf 'Retired Concept Current Year'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198565</classIRI>
<classLabel>Myeloid/Lymphoid Neoplasms with ETV6-ABL1</classLabel>
<newAxiom>'Myeloid/Lymphoid Neoplasms with ETV6-ABL1' EquivalentTo 'Myeloid/Lymphoid Neoplasms with Eosinophilia and Tyrosine Kinase Gene Fusions' and ('Disease_Has_Molecular_Abnormality' some 'ETV6-ABL1 Fusion Protein Expression') and ('Disease_Has_Cytogenetic_Abnormality' some 't(9;12)(q34;p13)')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198566</classIRI>
<classLabel>Nucleic Acid Specimen</classLabel>
<newAxiom>'Nucleic Acid Specimen' SubClassOf 'Biospecimen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198567</classIRI>
<classLabel>DNA Specimen</classLabel>
<newAxiom>'DNA Specimen' SubClassOf 'Nucleic Acid Specimen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198568</classIRI>
<classLabel>RNA Specimen</classLabel>
<newAxiom>'RNA Specimen' SubClassOf 'Nucleic Acid Specimen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198569</classIRI>
<classLabel>GenomePlex Whole Genome Amplified DNA</classLabel>
<newAxiom>'GenomePlex Whole Genome Amplified DNA' SubClassOf 'DNA Specimen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198570</classIRI>
<classLabel>Applied Biosystems Capillary Sequencing</classLabel>
<newAxiom>'Applied Biosystems Capillary Sequencing' SubClassOf 'Capillary Sequencing'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198571</classIRI>
<classLabel>Focal Bone Marrow Involvement</classLabel>
<newAxiom>'Focal Bone Marrow Involvement' SubClassOf 'Bone Marrow Involvement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198572</classIRI>
<classLabel>Diffuse Bone Marrow Involvement</classLabel>
<newAxiom>'Diffuse Bone Marrow Involvement' SubClassOf 'Bone Marrow Involvement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198573</classIRI>
<classLabel>Bone Marrow Mastocytosis</classLabel>
<newAxiom>'Bone Marrow Mastocytosis' EquivalentTo 'Indolent Systemic Mastocytosis' and ('Disease_Has_Finding' some 'Focal Bone Marrow Involvement') and ('Disease_Excludes_Finding' some 'Cutaneous Involvement')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198574</classIRI>
<classLabel>Autosomal Recessive Distal Renal Tubular Acidosis-4 with Hemolytic Anemia</classLabel>
<newAxiom>'Autosomal Recessive Distal Renal Tubular Acidosis-4 with Hemolytic Anemia' SubClassOf 'Disease_Mapped_To_Gene' some 'SLC4A1 Gene'</newAxiom>
<newAxiom>'Autosomal Recessive Distal Renal Tubular Acidosis-4 with Hemolytic Anemia' SubClassOf 'Distal Renal Tubular Acidosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198575</classIRI>
<classLabel>Cerebral Creatine Deficiency Syndrome 3</classLabel>
<newAxiom>'Cerebral Creatine Deficiency Syndrome 3' SubClassOf 'Syndrome'</newAxiom>
<newAxiom>'Cerebral Creatine Deficiency Syndrome 3' SubClassOf 'Disease_Mapped_To_Gene' some 'GATM Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198576</classIRI>
<classLabel>Developmental And Epileptic Encephalopathy 66</classLabel>
<newAxiom>'Developmental And Epileptic Encephalopathy 66' SubClassOf 'Developmental and Epileptic Encephalopathy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198577</classIRI>
<classLabel>Mouse Thymoma</classLabel>
<newAxiom>'Mouse Thymoma' SubClassOf 'Mouse Epithelial Cell Neoplasms'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198578</classIRI>
<classLabel>Female-Restricted Wieacker-Wolff Syndrome</classLabel>
<newAxiom>'Female-Restricted Wieacker-Wolff Syndrome' SubClassOf 'Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198579</classIRI>
<classLabel>PD-L1 Expression 1-49 Percent</classLabel>
<newAxiom>'PD-L1 Expression 1-49 Percent' SubClassOf 'Immunohistochemical Status of PD-L1'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198580</classIRI>
<classLabel>Clonal Monocytosis of Undetermined Significance</classLabel>
<newAxiom>'Clonal Monocytosis of Undetermined Significance' EquivalentTo 'Myelodysplastic/Myeloproliferative Neoplasm' and ('Disease_Has_Finding' some 'Monocytosis') and ('Disease_Has_Finding' some 'Absence of Bone Marrow Dysplasia') and ('Disease_Excludes_Finding' some 'Cytopenia') and ('Disease_Excludes_Finding' some 'Blast Cells Increased in Bone Marrow')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198581</classIRI>
<classLabel>Myelodysplastic/Myeloproliferative Neoplasm with SF3B1 Mutation and Thrombocytosis</classLabel>
<newAxiom>'Myelodysplastic/Myeloproliferative Neoplasm with SF3B1 Mutation and Thrombocytosis' EquivalentTo 'Myelodysplastic/Myeloproliferative Neoplasm' and ('Disease_Has_Molecular_Abnormality' some 'SF3B1 Gene Mutation') and ('Disease_Has_Finding' some 'Thrombocytosis') and ('Disease_Has_Finding' some 'Myeloblasts Under 5 Percent of Bone Marrow Nucleated Cells') and ('Disease_Has_Finding' some 'Myeloblasts Under 1 Percent of Peripheral Blood White Cells') and ('Disease_Has_Associated_Disease' some 'Anemia') and ('Disease_Excludes_Molecular_Abnormality' some 'Tyrosine Kinase Gene Fusion') and ('Disease_Mapped_To_Gene' some 'SF3B1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198582</classIRI>
<classLabel>Clonal Cytopenia with Monocytosis of Undetermined Significance</classLabel>
<newAxiom>'Clonal Cytopenia with Monocytosis of Undetermined Significance' EquivalentTo 'Myelodysplastic/Myeloproliferative Neoplasm' and ('Disease_Has_Finding' some 'Cytopenia') and ('Disease_Has_Finding' some 'Monocytosis') and ('Disease_Has_Finding' some 'Absence of Bone Marrow Dysplasia') and ('Disease_Excludes_Finding' some 'Blast Cells Increased in Bone Marrow')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198583</classIRI>
<classLabel>Myelodysplastic/Myeloproliferative Neoplasm with Isolated Isochromosome (17q)</classLabel>
<newAxiom>'Myelodysplastic/Myeloproliferative Neoplasm with Isolated Isochromosome (17q)' EquivalentTo 'Myelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified' and ('Disease_Has_Cytogenetic_Abnormality' some 'i(17q)')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198584</classIRI>
<classLabel>Iodine I 131 Radiation Therapy</classLabel>
<newAxiom>'Iodine I 131 Radiation Therapy' SubClassOf 'Isotope Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198585</classIRI>
<classLabel>Bisphosphonate Therapy</classLabel>
<newAxiom>'Bisphosphonate Therapy' SubClassOf 'Single Agent Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198586</classIRI>
<classLabel>Ancillary Treatment</classLabel>
<newAxiom>'Ancillary Treatment' SubClassOf 'Therapeutic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198587</classIRI>
<classLabel>Myelodysplastic Syndrome with Mutated SF3B1</classLabel>
<newAxiom>'Myelodysplastic Syndrome with Mutated SF3B1' EquivalentTo 'Myelodysplastic Syndrome' and ('Disease_Has_Molecular_Abnormality' some 'SF3B1 Gene Mutation') and ('Disease_Has_Finding' some 'Blasts Under 5 Percent of Bone Marrow Nucleated Cells') and ('Disease_Has_Finding' some 'Myeloblasts Under 2 Percent of Peripheral Blood White Cells') and ('Disease_Mapped_To_Gene' some 'SF3B1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198588</classIRI>
<classLabel>Myelodysplastic Syndrome, Not Otherwise Specified without Dysplasia</classLabel>
<newAxiom>'Myelodysplastic Syndrome, Not Otherwise Specified without Dysplasia' EquivalentTo 'Premalignant Hematologic Condition' and ('Disease_Has_Finding' some 'Cytopenia') and ('Disease_Has_Finding' some 'Myeloblasts Under 2 Percent of Peripheral Blood White Cells') and ('Disease_Has_Finding' some 'Myeloblasts Under 5 Percent of Bone Marrow Nucleated Cells') and ('Disease_Has_Finding' some 'Absence of Bone Marrow Dysplasia')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198589</classIRI>
<classLabel>Myelodysplastic Syndrome, Not Otherwise Specified</classLabel>
<newAxiom>'Myelodysplastic Syndrome, Not Otherwise Specified' EquivalentTo 'Myelodysplastic Syndrome' and ('Disease_Has_Finding' some 'Not Otherwise Specified Lesion') and ('Disease_Excludes_Finding' some 'Myeloblasts 10-19 Percent of Bone Marrow Nucleated Cells') and ('Disease_Excludes_Finding' some 'Myeloblasts 10-19 Percent of Peripheral Blood White Cells')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198590</classIRI>
<classLabel>Unclassifiable Lesion</classLabel>
<newAxiom>'Unclassifiable Lesion' SubClassOf 'Lesion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198591</classIRI>
<classLabel>Outbred Mouse Strain</classLabel>
<newAxiom>'Outbred Mouse Strain' SubClassOf 'Mouse Strains'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198592</classIRI>
<classLabel>CD-1 IGS Mouse</classLabel>
<newAxiom>'CD-1 IGS Mouse' SubClassOf 'Outbred Mouse Strain'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198593</classIRI>
<classLabel>Myeloid Neoplasm with Mutated TP53</classLabel>
<newAxiom>'Myeloid Neoplasm with Mutated TP53' EquivalentTo 'Myeloid Neoplasm' and ('Disease_Has_Molecular_Abnormality' some 'TP53 Gene Mutation') and ('Disease_Mapped_To_Gene' some 'TP53 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198594</classIRI>
<classLabel>Myelodysplastic Syndrome with Mutated TP53</classLabel>
<newAxiom>'Myelodysplastic Syndrome with Mutated TP53' EquivalentTo 'Myeloid Neoplasm with Mutated TP53' and 'Myelodysplastic Syndrome' and ('Disease_Has_Finding' some 'Blasts Under 10 Percent of Peripheral Blood White Cells') and ('Disease_Has_Finding' some 'Blasts Under 10 Percent of Bone Marrow Nucleated Cells')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198595</classIRI>
<classLabel>Myelodysplastic Syndrome/Acute Myeloid Leukemia with Mutated TP53</classLabel>
<newAxiom>'Myelodysplastic Syndrome/Acute Myeloid Leukemia with Mutated TP53' EquivalentTo 'Myeloid Neoplasm with Mutated TP53' and 'Myelodysplastic Syndrome/Acute Myeloid Leukemia' and ('Disease_Has_Finding' some 'Blasts 10-19 Percent of Peripheral Blood White Cells') and ('Disease_Has_Finding' some 'Blasts 10-19 Percent of Bone Marrow Nucleated Cells')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198596</classIRI>
<classLabel>Acute Myeloid Leukemia with Mutated TP53</classLabel>
<newAxiom>'Acute Myeloid Leukemia with Mutated TP53' EquivalentTo 'Myeloid Neoplasm with Mutated TP53' and 'Acute Myeloid Leukemia with Gene Mutations' and ('Disease_Has_Finding' some 'Blasts 20 Percent or More of Peripheral Blood White Cells') and ('Disease_Has_Finding' some 'Blasts 20 Percent or More of Bone Marrow Nucleated Cells')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198597</classIRI>
<classLabel>Myelodysplastic Syndrome/Acute Myeloid Leukemia, Not Otherwise Specified</classLabel>
<newAxiom>'Myelodysplastic Syndrome/Acute Myeloid Leukemia, Not Otherwise Specified' EquivalentTo 'Myelodysplastic Syndrome/Acute Myeloid Leukemia' and ('Disease_Has_Finding' some 'Not Otherwise Specified Lesion')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198598</classIRI>
<classLabel>Rat Tunica Vaginalis Sarcomatoid Mesothelioma</classLabel>
<newAxiom>'Rat Tunica Vaginalis Sarcomatoid Mesothelioma' SubClassOf 'Rat Malignant Mesothelioma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198599</classIRI>
<classLabel>Dilated Cardiomyopathy-1D</classLabel>
<newAxiom>'Dilated Cardiomyopathy-1D' SubClassOf 'Dilated Cardiomyopathy'</newAxiom>
<newAxiom>'Dilated Cardiomyopathy-1D' SubClassOf 'Disease_Mapped_To_Gene' some 'TNNT2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198549</classIRI>
<classLabel>Complement Component C1</classLabel>
<newAxiom>'Complement Component C1' SubClassOf 'Protein or Riboprotein Complex'</newAxiom>
<newAxiom>'Complement Component C1' SubClassOf 'Complement Component Protein'</newAxiom>
<newAxiom>'Complement Component C1' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Complement Activation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198550</classIRI>
<classLabel>Ibrutinib/Lenalidomide/Rituximab Regimen</classLabel>
<newAxiom>'Ibrutinib/Lenalidomide/Rituximab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Rituximab'</newAxiom>
<newAxiom>'Ibrutinib/Lenalidomide/Rituximab Regimen' SubClassOf 'Regimen Used to Treat Non-Hodgkin Lymphoma'</newAxiom>
<newAxiom>'Ibrutinib/Lenalidomide/Rituximab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Ibrutinib'</newAxiom>
<newAxiom>'Ibrutinib/Lenalidomide/Rituximab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Lenalidomide'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198551</classIRI>
<classLabel>Clofarabine/Idarubicin Regimen</classLabel>
<newAxiom>'Clofarabine/Idarubicin Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Clofarabine'</newAxiom>
<newAxiom>'Clofarabine/Idarubicin Regimen' SubClassOf 'Regimen Used to Treat Acute Myeloid Leukemia'</newAxiom>
<newAxiom>'Clofarabine/Idarubicin Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Idarubicin'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198552</classIRI>
<classLabel>Ibrutinib/High-dose Methotrexate/Rituximab Regimen</classLabel>
<newAxiom>'Ibrutinib/High-dose Methotrexate/Rituximab Regimen' SubClassOf 'Regimen Used to Treat Central Nervous System Neoplasm'</newAxiom>
<newAxiom>'Ibrutinib/High-dose Methotrexate/Rituximab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Rituximab'</newAxiom>
<newAxiom>'Ibrutinib/High-dose Methotrexate/Rituximab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Methotrexate Sodium'</newAxiom>
<newAxiom>'Ibrutinib/High-dose Methotrexate/Rituximab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Ibrutinib'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198553</classIRI>
<classLabel>Clofarabine/Cytarabine/Idarubicin Regimen</classLabel>
<newAxiom>'Clofarabine/Cytarabine/Idarubicin Regimen' SubClassOf 'Regimen Used to Treat Acute Myeloid Leukemia'</newAxiom>
<newAxiom>'Clofarabine/Cytarabine/Idarubicin Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Clofarabine'</newAxiom>
<newAxiom>'Clofarabine/Cytarabine/Idarubicin Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Idarubicin Hydrochloride'</newAxiom>
<newAxiom>'Clofarabine/Cytarabine/Idarubicin Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Cytarabine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198554</classIRI>
<classLabel>Brentuximab Vedotin/Nivolumab Regimen</classLabel>
<newAxiom>'Brentuximab Vedotin/Nivolumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Brentuximab Vedotin'</newAxiom>
<newAxiom>'Brentuximab Vedotin/Nivolumab Regimen' SubClassOf 'Regimen Used to Treat Hodgkin Lymphoma'</newAxiom>
<newAxiom>'Brentuximab Vedotin/Nivolumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Nivolumab'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198555</classIRI>
<classLabel>Myeloproliferative Neoplasm, BCR-ABL1 Negative</classLabel>
<newAxiom>'Myeloproliferative Neoplasm, BCR-ABL1 Negative' EquivalentTo 'Myeloproliferative Neoplasm' and ('Disease_Excludes_Abnormal_Cell' some 'Segmented Neutrophil') and ('Disease_Excludes_Molecular_Abnormality' some 'BCR-ABL1 Fusion Protein Expression') and ('Disease_Excludes_Cytogenetic_Abnormality' some 't(9;22)(q34.1;q11.2)') and ('Disease_Excludes_Cytogenetic_Abnormality' some 'Philadelphia Chromosome') and ('Disease_Excludes_Finding' some 'Not Otherwise Specified Lesion') and ('Disease_Excludes_Finding' some 'Eosinophilia') and ('Disease_Excludes_Finding' some 'Neutrophilia')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198557</classIRI>
<classLabel>Brentuximab Vedotin/Dacarbazine Regimen</classLabel>
<newAxiom>'Brentuximab Vedotin/Dacarbazine Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Dacarbazine'</newAxiom>
<newAxiom>'Brentuximab Vedotin/Dacarbazine Regimen' SubClassOf 'Regimen Used to Treat Hodgkin Lymphoma'</newAxiom>
<newAxiom>'Brentuximab Vedotin/Dacarbazine Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Brentuximab Vedotin'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198558</classIRI>
<classLabel>Tyrosine Kinase Gene Fusion</classLabel>
<newAxiom>'Tyrosine Kinase Gene Fusion' SubClassOf 'Gene Fusion Abnormality'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198559</classIRI>
<classLabel>Myeloid/Lymphoid Neoplasms with FLT3 Rearrangement</classLabel>
<newAxiom>'Myeloid/Lymphoid Neoplasms with FLT3 Rearrangement' EquivalentTo 'Myeloid/Lymphoid Neoplasms with Eosinophilia and Tyrosine Kinase Gene Fusions' and ('Disease_Has_Molecular_Abnormality' some 'FLT3 Gene Rearrangement') and ('Disease_May_Have_Cytogenetic_Abnormality' some 't(12;13)(p13.2;q12.2)') and ('Disease_Mapped_To_Gene' some 'FLT3 Gene') and ('Disease_May_Have_Molecular_Abnormality' some 'ETV6-FLT3 Fusion Protein Expression')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198560</classIRI>
<classLabel>FLT3 Gene Rearrangement</classLabel>
<newAxiom>'FLT3 Gene Rearrangement' SubClassOf 'Chromosome 13q Abnormality'</newAxiom>
<newAxiom>'FLT3 Gene Rearrangement' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'FLT3 Gene'</newAxiom>
<newAxiom>'FLT3 Gene Rearrangement' SubClassOf 'Receptor Tyrosine Kinase Gene Rearrangement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198682</classIRI>
<classLabel>Juvenile Myelomonocytic Leukemia Associated with Noonan Syndrome-Like Disorder</classLabel>
<newAxiom>'Juvenile Myelomonocytic Leukemia Associated with Noonan Syndrome-Like Disorder' EquivalentTo 'Hematologic Neoplasm with Germline Predisposition Associated with a Constitutional Disorder Affecting Multiple Organ Systems' and 'Juvenile Myelomonocytic Leukemia' and ('Disease_Has_Associated_Disease' some 'Noonan Syndrome-Like Disorder')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198683</classIRI>
<classLabel>Acute Lymphoblastic Leukemia with Germline Predisposition</classLabel>
<newAxiom>'Acute Lymphoblastic Leukemia with Germline Predisposition' EquivalentTo 'Acute Lymphoblastic Leukemia' and ('Disease_Has_Molecular_Abnormality' some 'Germline Variation')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198684</classIRI>
<classLabel>Acute Lymphoblastic Leukemia with Germline PAX5 Mutation</classLabel>
<newAxiom>'Acute Lymphoblastic Leukemia with Germline PAX5 Mutation' EquivalentTo 'Acute Lymphoblastic Leukemia with Germline Predisposition' and ('Disease_Has_Molecular_Abnormality' some 'PAX5 Gene Mutation') and ('Disease_Mapped_To_Gene' some 'PAX5 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198685</classIRI>
<classLabel>Acute Lymphoblastic Leukemia with Germline IKZF1 Mutation</classLabel>
<newAxiom>'Acute Lymphoblastic Leukemia with Germline IKZF1 Mutation' EquivalentTo 'Acute Lymphoblastic Leukemia with Germline Predisposition' and ('Disease_Has_Molecular_Abnormality' some 'IKZF1 Gene Mutation') and ('Disease_Mapped_To_Gene' some 'IKZF1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198686</classIRI>
<classLabel>Anti-CTLA-4 Monoclonal Antibody-IL-15/IL-15Ra Fusion Protein JK08</classLabel>
<newAxiom>'Anti-CTLA-4 Monoclonal Antibody-IL-15/IL-15Ra Fusion Protein JK08' SubClassOf 'CTLA-4-targeting Agent'</newAxiom>
<newAxiom>'Anti-CTLA-4 Monoclonal Antibody-IL-15/IL-15Ra Fusion Protein JK08' SubClassOf 'Antineoplastic Biological Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198687</classIRI>
<classLabel>Autologous CAR-T Cells B4T2-001</classLabel>
<newAxiom>'Autologous CAR-T Cells B4T2-001' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Autologous CAR-T Cells B4T2-001' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous CAR-T Cells B4T2-001' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198688</classIRI>
<classLabel>AXL/FLT3 Inhibitor TT-00973</classLabel>
<newAxiom>'AXL/FLT3 Inhibitor TT-00973' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'AXL/FLT3 Inhibitor TT-00973' SubClassOf 'Tyrosine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198689</classIRI>
<classLabel>Anti-PD-L1/Anti-VEGF Bispecific Antibody Fusion Protein B1962</classLabel>
<newAxiom>'Anti-PD-L1/Anti-VEGF Bispecific Antibody Fusion Protein B1962' SubClassOf 'VEGF-targeting Agent'</newAxiom>
<newAxiom>'Anti-PD-L1/Anti-VEGF Bispecific Antibody Fusion Protein B1962' SubClassOf 'Angiogenesis Inhibitor'</newAxiom>
<newAxiom>'Anti-PD-L1/Anti-VEGF Bispecific Antibody Fusion Protein B1962' SubClassOf 'Immune Checkpoint Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198690</classIRI>
<classLabel>SMARCA2 Degrader PRT3789</classLabel>
<newAxiom>'SMARCA2 Degrader PRT3789' SubClassOf 'Signal Transduction Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198691</classIRI>
<classLabel>EGFR Inhibitor WJ13404</classLabel>
<newAxiom>'EGFR Inhibitor WJ13404' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'EGFR Inhibitor WJ13404' SubClassOf 'Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198692</classIRI>
<classLabel>PI3K-alpha Inhibitor TOS-358</classLabel>
<newAxiom>'PI3K-alpha Inhibitor TOS-358' SubClassOf 'Phosphatidylinositide 3-Kinase Inhibitor'</newAxiom>
<newAxiom>'PI3K-alpha Inhibitor TOS-358' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198693</classIRI>
<classLabel>Technetium Tc-99m-MIRC213</classLabel>
<newAxiom>'Technetium Tc-99m-MIRC213' SubClassOf 'Radioimmunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198694</classIRI>
<classLabel>Topical Piper crocatum Extract</classLabel>
<newAxiom>'Topical Piper crocatum Extract' SubClassOf 'Topical Preparation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198695</classIRI>
<classLabel>Anti-CCR8 Monoclonal Antibody SRF114</classLabel>
<newAxiom>'Anti-CCR8 Monoclonal Antibody SRF114' SubClassOf 'Anti-CCR8 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198696</classIRI>
<classLabel>Pan-FGFR Inhibitor ABSK-121</classLabel>
<newAxiom>'Pan-FGFR Inhibitor ABSK-121' SubClassOf 'FGFR Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198697</classIRI>
<classLabel>Site Specific Immunomodulator QBECO</classLabel>
<newAxiom>'Site Specific Immunomodulator QBECO' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198698</classIRI>
<classLabel>Anti-CLDN18.2 Heavy Chain Antibody Fc Fusion Protein DR30303</classLabel>
<newAxiom>'Anti-CLDN18.2 Heavy Chain Antibody Fc Fusion Protein DR30303' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198699</classIRI>
<classLabel>Vaginal Hyaluronic Acid/Lactic Acid-based Formulation IC-LC02S2Q2</classLabel>
<newAxiom>'Vaginal Hyaluronic Acid/Lactic Acid-based Formulation IC-LC02S2Q2' SubClassOf 'Topical Preparation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198600</classIRI>
<classLabel>Goat Neoplasm</classLabel>
<newAxiom>'Goat Neoplasm' SubClassOf 'Non-Human or Experimental Organism Neoplasm by Organism'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198601</classIRI>
<classLabel>Goat Melanoma</classLabel>
<newAxiom>'Goat Melanoma' SubClassOf 'Goat Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198602</classIRI>
<classLabel>Parkinson Disease 1, Autosomal Dominant</classLabel>
<newAxiom>'Parkinson Disease 1, Autosomal Dominant' SubClassOf 'Parkinson's Disease'</newAxiom>
<newAxiom>'Parkinson Disease 1, Autosomal Dominant' SubClassOf 'Disease_Mapped_To_Gene' some 'SNCA Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198603</classIRI>
<classLabel>Parkinson Disease 2, Autosomal Recessive Juvenile</classLabel>
<newAxiom>'Parkinson Disease 2, Autosomal Recessive Juvenile' SubClassOf 'Disease_Mapped_To_Gene' some 'PRKN Gene'</newAxiom>
<newAxiom>'Parkinson Disease 2, Autosomal Recessive Juvenile' SubClassOf 'Parkinson's Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198604</classIRI>
<classLabel>Parkinson Disease 4, Autosomal Dominant</classLabel>
<newAxiom>'Parkinson Disease 4, Autosomal Dominant' SubClassOf 'Disease_Mapped_To_Gene' some 'SNCA Gene'</newAxiom>
<newAxiom>'Parkinson Disease 4, Autosomal Dominant' SubClassOf 'Parkinson's Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198605</classIRI>
<classLabel>Parkinson Disease 8, Autosomal Dominant</classLabel>
<newAxiom>'Parkinson Disease 8, Autosomal Dominant' SubClassOf 'Disease_Mapped_To_Gene' some 'LRRK2 Gene'</newAxiom>
<newAxiom>'Parkinson Disease 8, Autosomal Dominant' SubClassOf 'Parkinson's Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198606</classIRI>
<classLabel>Parkinson Disease 7, Autosomal Recessive Early-Onset</classLabel>
<newAxiom>'Parkinson Disease 7, Autosomal Recessive Early-Onset' SubClassOf 'Parkinson's Disease'</newAxiom>
<newAxiom>'Parkinson Disease 7, Autosomal Recessive Early-Onset' SubClassOf 'Disease_Mapped_To_Gene' some 'PARK7 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198607</classIRI>
<classLabel>Parkinson Disease 15, Autosomal Recessive Early-Onset</classLabel>
<newAxiom>'Parkinson Disease 15, Autosomal Recessive Early-Onset' SubClassOf 'Parkinson's Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198608</classIRI>
<classLabel>Parkinson Disease 19A, Juvenile-Onset</classLabel>
<newAxiom>'Parkinson Disease 19A, Juvenile-Onset' SubClassOf 'Parkinson's Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198609</classIRI>
<classLabel>Parkinson Disease 19B, Early-Onset</classLabel>
<newAxiom>'Parkinson Disease 19B, Early-Onset' SubClassOf 'Parkinson's Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198610</classIRI>
<classLabel>VISS Syndrome</classLabel>
<newAxiom>'VISS Syndrome' SubClassOf 'Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198611</classIRI>
<classLabel>Malignant Effusion</classLabel>
<newAxiom>'Malignant Effusion' SubClassOf 'Effusion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198612</classIRI>
<classLabel>CFI Gene</classLabel>
<newAxiom>'CFI Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Negative Regulation of Complement Activation'</newAxiom>
<newAxiom>'CFI Gene' SubClassOf 'Peptidase Gene'</newAxiom>
<newAxiom>'CFI Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Cleavage'</newAxiom>
<newAxiom>'CFI Gene' SubClassOf 'Complement Component Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198613</classIRI>
<classLabel>CFI wt Allele</classLabel>
<newAxiom>'CFI wt Allele' EquivalentTo 'CFI Gene' and ('Gene_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_In_Chromosomal_Location' some '4q25')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198614</classIRI>
<classLabel>Complement Factor I</classLabel>
<newAxiom>'Complement Factor I' EquivalentTo 'Serine Protease' and 'Complement Component Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Scavenger Receptor Cysteine-Rich Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Negative Regulation of Complement Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Cleavage') and ('Gene_Product_Encoded_By_Gene' some 'CFI Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198615</classIRI>
<classLabel>Resectable Esophageal Adenocarcinoma</classLabel>
<newAxiom>'Resectable Esophageal Adenocarcinoma' EquivalentTo 'Resectable Digestive System Carcinoma' and 'Esophageal Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198616</classIRI>
<classLabel>Resectable Ampulla of Vater Adenocarcinoma</classLabel>
<newAxiom>'Resectable Ampulla of Vater Adenocarcinoma' EquivalentTo 'Resectable Digestive System Carcinoma' and 'Ampulla of Vater Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198617</classIRI>
<classLabel>Resectable Gallbladder Adenocarcinoma</classLabel>
<newAxiom>'Resectable Gallbladder Adenocarcinoma' EquivalentTo 'Resectable Digestive System Carcinoma' and 'Gallbladder Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198618</classIRI>
<classLabel>Sexuality Answer</classLabel>
<newAxiom>'Sexuality Answer' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198619</classIRI>
<classLabel>Have not Figured Out or Is Figuring Out Sexuality</classLabel>
<newAxiom>'Have not Figured Out or Is Figuring Out Sexuality' SubClassOf 'Sexuality Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198620</classIRI>
<classLabel>Consider Self Mostly Straight</classLabel>
<newAxiom>'Consider Self Mostly Straight' SubClassOf 'Sexuality Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198621</classIRI>
<classLabel>Does Not Have Sexuality</classLabel>
<newAxiom>'Does Not Have Sexuality' SubClassOf 'Sexuality Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198622</classIRI>
<classLabel>CFHR5 Gene</classLabel>
<newAxiom>'CFHR5 Gene' SubClassOf 'Complement Component Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198623</classIRI>
<classLabel>Do Not Use Labels for Sexuality</classLabel>
<newAxiom>'Do Not Use Labels for Sexuality' SubClassOf 'Sexuality Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198624</classIRI>
<classLabel>CFHR5 wt Allele</classLabel>
<newAxiom>'CFHR5 wt Allele' EquivalentTo 'CFHR5 Gene' and ('Gene_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_In_Chromosomal_Location' some '1q31.3')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198625</classIRI>
<classLabel>Does Not Know Their Sexuality</classLabel>
<newAxiom>'Does Not Know Their Sexuality' SubClassOf 'Sexuality Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198626</classIRI>
<classLabel>Some Other Sexual Orientation</classLabel>
<newAxiom>'Some Other Sexual Orientation' SubClassOf 'Sexuality Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198627</classIRI>
<classLabel>Complement Factor H-Related Protein 5</classLabel>
<newAxiom>'Complement Factor H-Related Protein 5' EquivalentTo 'Complement Component Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Expressed_In_Tissue' some 'Blood') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Sushi Domain') and ('Gene_Product_Encoded_By_Gene' some 'CFHR5 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198628</classIRI>
<classLabel>CHRNE Gene</classLabel>
<newAxiom>'CHRNE Gene' SubClassOf 'Ion Channel Protein Gene'</newAxiom>
<newAxiom>'CHRNE Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Neuronal Transmission'</newAxiom>
<newAxiom>'CHRNE Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Muscle Contraction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198629</classIRI>
<classLabel>CHRNE wt Allele</classLabel>
<newAxiom>'CHRNE wt Allele' EquivalentTo 'CHRNE Gene' and ('Gene_Is_Element_In_Pathway' some 'Neuroactive Ligand-Receptor Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'ERBB2/ERBB3 Signaling Pathway') and ('Gene_In_Chromosomal_Location' some '17p13.2')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198630</classIRI>
<classLabel>Acetylcholine Receptor Subunit Epsilon</classLabel>
<newAxiom>'Acetylcholine Receptor Subunit Epsilon' EquivalentTo 'Ion Channel Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Neuroactive Ligand-Receptor Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'ERBB2/ERBB3 Signaling Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Gated Ion Channel') and ('Gene_Product_Has_Associated_Anatomy' some 'Postsynaptic Membrane') and ('Gene_Product_Is_Physical_Part_Of' some 'Nicotinic Acetylcholine Receptor') and ('Gene_Product_Has_Biochemical_Function' some 'Cell Surface Receptor') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Neuronal Transmission') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Muscle Contraction') and ('Gene_Product_Encoded_By_Gene' some 'CHRNE Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198631</classIRI>
<classLabel>CHST14 Gene</classLabel>
<newAxiom>'CHST14 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Biosynthetic Process'</newAxiom>
<newAxiom>'CHST14 Gene' SubClassOf 'Transferase Gene'</newAxiom>
<newAxiom>'CHST14 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Carbohydrate Metabolic Process'</newAxiom>
<newAxiom>'CHST14 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Metabolism Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198632</classIRI>
<classLabel>CHST14 wt Allele</classLabel>
<newAxiom>'CHST14 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Glycosaminoglycan Biosynthesis Pathway - Chondroitin Sulfate'</newAxiom>
<newAxiom>'CHST14 wt Allele' SubClassOf 'CHST14 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198633</classIRI>
<classLabel>Carbohydrate Sulfotransferase 14</classLabel>
<newAxiom>'Carbohydrate Sulfotransferase 14' EquivalentTo 'Transferase' and ('Gene_Product_Is_Element_In_Pathway' some 'Glycosaminoglycan Biosynthesis Pathway - Chondroitin Sulfate') and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Golgi Apparatus') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Sulfotransferase') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Biosynthetic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Carbohydrate Metabolic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Metabolism Process') and ('Gene_Product_Encoded_By_Gene' some 'CHST14 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198634</classIRI>
<classLabel>CD19-targeting Agent</classLabel>
<newAxiom>'CD19-targeting Agent' SubClassOf 'Targeted Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198635</classIRI>
<classLabel>Deafness or Have Difficulty Hearing</classLabel>
<newAxiom>'Deafness or Have Difficulty Hearing' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
<newAxiom>'Deafness or Have Difficulty Hearing' SubClassOf 'Hearing Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198636</classIRI>
<classLabel>Blindness or Have Difficulty Seeing</classLabel>
<newAxiom>'Blindness or Have Difficulty Seeing' SubClassOf 'Vision Question'</newAxiom>
<newAxiom>'Blindness or Have Difficulty Seeing' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198637</classIRI>
<classLabel>Have Difficulty Concentrating, Remembering, and Deciding</classLabel>
<newAxiom>'Have Difficulty Concentrating, Remembering, and Deciding' SubClassOf 'Memory Question'</newAxiom>
<newAxiom>'Have Difficulty Concentrating, Remembering, and Deciding' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198638</classIRI>
<classLabel>Have Difficulty Walking or Climbing Stairs</classLabel>
<newAxiom>'Have Difficulty Walking or Climbing Stairs' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
<newAxiom>'Have Difficulty Walking or Climbing Stairs' SubClassOf 'Walking Question'</newAxiom>
<newAxiom>'Have Difficulty Walking or Climbing Stairs' SubClassOf 'Climbing Steps or Stairs Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198639</classIRI>
<classLabel>Have Difficulty Dressing or Bathing</classLabel>
<newAxiom>'Have Difficulty Dressing or Bathing' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
<newAxiom>'Have Difficulty Dressing or Bathing' SubClassOf 'Play or Do Physical Activity Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198640</classIRI>
<classLabel>Have Difficulty Doing Errands Alone</classLabel>
<newAxiom>'Have Difficulty Doing Errands Alone' SubClassOf 'Play or Do Physical Activity Question'</newAxiom>
<newAxiom>'Have Difficulty Doing Errands Alone' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198642</classIRI>
<classLabel>IL-34 Inhibitor</classLabel>
<newAxiom>'IL-34 Inhibitor' SubClassOf 'Interleukin Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198643</classIRI>
<classLabel>CSF1R-targeting Agent</classLabel>
<newAxiom>'CSF1R-targeting Agent' SubClassOf 'Targeted Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198644</classIRI>
<classLabel>CSF1-targeting Agent</classLabel>
<newAxiom>'CSF1-targeting Agent' SubClassOf 'Targeted Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198645</classIRI>
<classLabel>Anti-CSF1R Monoclonal Antibody</classLabel>
<newAxiom>'Anti-CSF1R Monoclonal Antibody' SubClassOf 'Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-CSF1R Monoclonal Antibody' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-CSF1R Monoclonal Antibody' SubClassOf 'CSF1R-targeting Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198646</classIRI>
<classLabel>CSF1R Inhibitor</classLabel>
<newAxiom>'CSF1R Inhibitor' SubClassOf 'CSF1R-targeting Agent'</newAxiom>
<newAxiom>'CSF1R Inhibitor' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198647</classIRI>
<classLabel>Autologous Anti-CD3/Anti-SLAMF7 Bispecific Antibody-armed Activated T-lymphocytes</classLabel>
<newAxiom>'Autologous Anti-CD3/Anti-SLAMF7 Bispecific Antibody-armed Activated T-lymphocytes' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous Anti-CD3/Anti-SLAMF7 Bispecific Antibody-armed Activated T-lymphocytes' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198648</classIRI>
<classLabel>MALDI-TOF DNA Sequencing</classLabel>
<newAxiom>'MALDI-TOF DNA Sequencing' SubClassOf 'DNA Sequencing'</newAxiom>
<newAxiom>'MALDI-TOF DNA Sequencing' SubClassOf 'Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198649</classIRI>
<classLabel>Endoscopic Ultrasound-Guided Radiofrequency Ablation</classLabel>
<newAxiom>'Endoscopic Ultrasound-Guided Radiofrequency Ablation' SubClassOf 'Image-Guided Local Therapy'</newAxiom>
<newAxiom>'Endoscopic Ultrasound-Guided Radiofrequency Ablation' SubClassOf 'Radiofrequency Ablation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198650</classIRI>
<classLabel>Some High School, No Diploma</classLabel>
<newAxiom>'Some High School, No Diploma' SubClassOf 'Education Level'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198651</classIRI>
<classLabel>Percent Area of Head and Neck Affected</classLabel>
<newAxiom>'Percent Area of Head and Neck Affected' SubClassOf 'Percentage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198652</classIRI>
<classLabel>Percent Area of Upper Limbs Affected</classLabel>
<newAxiom>'Percent Area of Upper Limbs Affected' SubClassOf 'Percentage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198653</classIRI>
<classLabel>Percent Area of Trunk Affected</classLabel>
<newAxiom>'Percent Area of Trunk Affected' SubClassOf 'Percentage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198654</classIRI>
<classLabel>Percent Area of Lower Limbs Affected</classLabel>
<newAxiom>'Percent Area of Lower Limbs Affected' SubClassOf 'Percentage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198655</classIRI>
<classLabel>Copper 64 Cu-labeled Macrophage-targeted Nanoparticle</classLabel>
<newAxiom>'Copper 64 Cu-labeled Macrophage-targeted Nanoparticle' SubClassOf 'Radioimmunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198656</classIRI>
<classLabel>Treating Investigator</classLabel>
<newAxiom>'Treating Investigator' SubClassOf 'Investigator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198657</classIRI>
<classLabel>Treatment of Choice</classLabel>
<newAxiom>'Treatment of Choice' SubClassOf 'Other Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198658</classIRI>
<classLabel>D3-Creatine Dilution</classLabel>
<newAxiom>'D3-Creatine Dilution' SubClassOf 'Skeletal Muscle Mass'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198659</classIRI>
<classLabel>Health Care System</classLabel>
<newAxiom>'Health Care System' SubClassOf 'Professional Organization or Group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198660</classIRI>
<classLabel>RAS Signal Transduction Pathway Activated</classLabel>
<newAxiom>'RAS Signal Transduction Pathway Activated' SubClassOf 'Positive Laboratory Test Result'</newAxiom>
<newAxiom>'RAS Signal Transduction Pathway Activated' SubClassOf 'Signaling Pathway Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198661</classIRI>
<classLabel>Juvenile Myelomonocytic Leukemia-Like Neoplasm</classLabel>
<newAxiom>'Juvenile Myelomonocytic Leukemia-Like Neoplasm' EquivalentTo 'Pediatric and/or Germline Mutation-Associated Myeloid Disorder' and ('Disease_Has_Finding' some 'Monocytosis') and ('Disease_Has_Finding' some 'Leukocytosis') and ('Disease_Has_Finding' some 'Blasts Under 20 Percent of Peripheral Blood White Cells') and ('Disease_Has_Finding' some 'Blasts Under 20 Percent of Bone Marrow Nucleated Cells') and ('Disease_Excludes_Molecular_Abnormality' some 'BCR-ABL1 Fusion Protein Expression') and ('Disease_Excludes_Finding' some 'RAS Signal Transduction Pathway Activated')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198662</classIRI>
<classLabel>Noonan Syndrome-Associated Myeloproliferative Disorder</classLabel>
<newAxiom>'Noonan Syndrome-Associated Myeloproliferative Disorder' EquivalentTo 'Pediatric and/or Germline Mutation-Associated Myeloid Disorder' and 'Childhood Hematopoietic and Lymphoid Cell Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Bone Marrow') and ('Disease_Has_Normal_Cell_Origin' some 'Myeloid Cell') and ('Disease_Has_Abnormal_Cell' some 'Neoplastic Myeloid Cell') and ('Disease_Has_Molecular_Abnormality' some 'Germline Variation') and ('Disease_Has_Associated_Disease' some 'Noonan Syndrome') and ('Disease_May_Have_Molecular_Abnormality' some 'RIT1 Gene Mutation') and ('Disease_May_Have_Molecular_Abnormality' some 'KRAS Gene Mutation') and ('Disease_May_Have_Molecular_Abnormality' some 'NRAS Gene Mutation') and ('Disease_May_Have_Molecular_Abnormality' some 'PTPN11 Gene Mutation')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198663</classIRI>
<classLabel>Pediatric and/or Germline Mutation-Associated Myeloid Disorder</classLabel>
<newAxiom>'Pediatric and/or Germline Mutation-Associated Myeloid Disorder' SubClassOf 'Myeloid Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198664</classIRI>
<classLabel>Somatic Mosaicism</classLabel>
<newAxiom>'Somatic Mosaicism' SubClassOf 'Mosaicism'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198665</classIRI>
<classLabel>Somatic DNA</classLabel>
<newAxiom>'Somatic DNA' SubClassOf 'Genomic DNA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198666</classIRI>
<classLabel>Ipilimumab/Nivolumab Followed by Nivolumab Regimen</classLabel>
<newAxiom>'Ipilimumab/Nivolumab Followed by Nivolumab Regimen' SubClassOf 'Regimen Used to Treat Malignant Renal Neoplasm'</newAxiom>
<newAxiom>'Ipilimumab/Nivolumab Followed by Nivolumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Ipilimumab'</newAxiom>
<newAxiom>'Ipilimumab/Nivolumab Followed by Nivolumab Regimen' SubClassOf 'Regimen Used to Treat Appendiceal Cancer'</newAxiom>
<newAxiom>'Ipilimumab/Nivolumab Followed by Nivolumab Regimen' SubClassOf 'Regimen Used to Treat Colorectal Carcinoma'</newAxiom>
<newAxiom>'Ipilimumab/Nivolumab Followed by Nivolumab Regimen' SubClassOf 'Regimen Used to Treat Malignant Neuroendocrine and Adrenal Neoplasm'</newAxiom>
<newAxiom>'Ipilimumab/Nivolumab Followed by Nivolumab Regimen' SubClassOf 'Regimen Used to Treat Malignant Intestinal Neoplasm'</newAxiom>
<newAxiom>'Ipilimumab/Nivolumab Followed by Nivolumab Regimen' SubClassOf 'Regimen Used to Treat Melanoma'</newAxiom>
<newAxiom>'Ipilimumab/Nivolumab Followed by Nivolumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Nivolumab'</newAxiom>
<newAxiom>'Ipilimumab/Nivolumab Followed by Nivolumab Regimen' SubClassOf 'Regimen Used to Treat Hepatobiliary Cancer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198667</classIRI>
<classLabel>Interferon gamma-1b Regimen</classLabel>
<newAxiom>'Interferon gamma-1b Regimen' SubClassOf 'Regimen Used to Treat Non-Hodgkin Lymphoma'</newAxiom>
<newAxiom>'Interferon gamma-1b Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Interferon Gamma-1b'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198668</classIRI>
<classLabel>Low-dose Ipilimumab/Pembrolizumab Regimen</classLabel>
<newAxiom>'Low-dose Ipilimumab/Pembrolizumab Regimen' SubClassOf 'Regimen Used to Treat Melanoma'</newAxiom>
<newAxiom>'Low-dose Ipilimumab/Pembrolizumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Ipilimumab'</newAxiom>
<newAxiom>'Low-dose Ipilimumab/Pembrolizumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Pembrolizumab'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198669</classIRI>
<classLabel>Clofarabine/Cyclophosphamide/Etoposide Regimen</classLabel>
<newAxiom>'Clofarabine/Cyclophosphamide/Etoposide Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Cyclophosphamide'</newAxiom>
<newAxiom>'Clofarabine/Cyclophosphamide/Etoposide Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Clofarabine'</newAxiom>
<newAxiom>'Clofarabine/Cyclophosphamide/Etoposide Regimen' SubClassOf 'Regimen Used to Treat Acute Lymphoblastic Leukemia'</newAxiom>
<newAxiom>'Clofarabine/Cyclophosphamide/Etoposide Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Etoposide'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198670</classIRI>
<classLabel>SC-EPOCH-RR  Regimen</classLabel>
<newAxiom>'SC-EPOCH-RR  Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Prednisone'</newAxiom>
<newAxiom>'SC-EPOCH-RR  Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Cyclophosphamide'</newAxiom>
<newAxiom>'SC-EPOCH-RR  Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Etoposide'</newAxiom>
<newAxiom>'SC-EPOCH-RR  Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Rituximab'</newAxiom>
<newAxiom>'SC-EPOCH-RR  Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Vincristine Sulfate'</newAxiom>
<newAxiom>'SC-EPOCH-RR  Regimen' SubClassOf 'Regimen Used to Treat Non-Hodgkin Lymphoma'</newAxiom>
<newAxiom>'SC-EPOCH-RR  Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Doxorubicin Hydrochloride'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198671</classIRI>
<classLabel>SC-EPOCH-R Regimen</classLabel>
<newAxiom>'SC-EPOCH-R Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Etoposide'</newAxiom>
<newAxiom>'SC-EPOCH-R Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Vincristine Sulfate'</newAxiom>
<newAxiom>'SC-EPOCH-R Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Prednisone'</newAxiom>
<newAxiom>'SC-EPOCH-R Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Doxorubicin Hydrochloride'</newAxiom>
<newAxiom>'SC-EPOCH-R Regimen' SubClassOf 'Regimen Used to Treat Non-Hodgkin Lymphoma'</newAxiom>
<newAxiom>'SC-EPOCH-R Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Cyclophosphamide'</newAxiom>
<newAxiom>'SC-EPOCH-R Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Rituximab'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198672</classIRI>
<classLabel>Modified CODOX-M-R Regimen</classLabel>
<newAxiom>'Modified CODOX-M-R Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Methotrexate'</newAxiom>
<newAxiom>'Modified CODOX-M-R Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Rituximab'</newAxiom>
<newAxiom>'Modified CODOX-M-R Regimen' SubClassOf 'Regimen_Has_Accepted_Use_For_Disease' some 'AIDS-Related Non-Hodgkin Lymphoma'</newAxiom>
<newAxiom>'Modified CODOX-M-R Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Doxorubicin'</newAxiom>
<newAxiom>'Modified CODOX-M-R Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Cyclophosphamide'</newAxiom>
<newAxiom>'Modified CODOX-M-R Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Vincristine'</newAxiom>
<newAxiom>'Modified CODOX-M-R Regimen' SubClassOf 'Regimen Used to Treat Non-Hodgkin Lymphoma'</newAxiom>
<newAxiom>'Modified CODOX-M-R Regimen' SubClassOf 'Regimen_Has_Accepted_Use_For_Disease' some 'Non-Hodgkin Lymphoma'</newAxiom>
<newAxiom>'Modified CODOX-M-R Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Leucovorin Calcium'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198673</classIRI>
<classLabel>Additional or Unexpected Endoscopic Procedure</classLabel>
<newAxiom>'Additional or Unexpected Endoscopic Procedure' SubClassOf 'Endoscopic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198674</classIRI>
<classLabel>Nullisomy</classLabel>
<newAxiom>'Nullisomy' SubClassOf 'Aneuploidy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198675</classIRI>
<classLabel>B-Scan Ocular Ultrasonography</classLabel>
<newAxiom>'B-Scan Ocular Ultrasonography' SubClassOf 'B-Mode Ultrasound Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198676</classIRI>
<classLabel>Sleepiness / Drowsiness / Somnolence</classLabel>
<newAxiom>'Sleepiness / Drowsiness / Somnolence' SubClassOf 'Symptom'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198677</classIRI>
<classLabel>Urinary Frequency / Polyuria</classLabel>
<newAxiom>'Urinary Frequency / Polyuria' SubClassOf 'Urinary System Finding'</newAxiom>
<newAxiom>'Urinary Frequency / Polyuria' SubClassOf 'Genitourinary Signs and Symptoms'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198678</classIRI>
<classLabel>Recurrent Mesonephric Adenocarcinoma</classLabel>
<newAxiom>'Recurrent Mesonephric Adenocarcinoma' EquivalentTo 'Recurrent Adenocarcinoma' and 'Mesonephric Adenocarcinoma' and 'Recurrent Female Reproductive System Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198679</classIRI>
<classLabel>Donor Relationship</classLabel>
<newAxiom>'Donor Relationship' SubClassOf 'Relationship'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198680</classIRI>
<classLabel>Juvenile Myelomonocytic Leukemia Associated with Neurofibromatosis</classLabel>
<newAxiom>'Juvenile Myelomonocytic Leukemia Associated with Neurofibromatosis' EquivalentTo 'Hematologic Neoplasm with Germline Predisposition Associated with a Constitutional Disorder Affecting Multiple Organ Systems' and 'Juvenile Myelomonocytic Leukemia' and ('Disease_Has_Associated_Disease' some 'Neurofibromatosis Type 1')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198681</classIRI>
<classLabel>Noonan Syndrome-Like Disorder</classLabel>
<newAxiom>'Noonan Syndrome-Like Disorder' EquivalentTo 'Hereditary Neoplastic Syndrome' and ('Disease_Has_Molecular_Abnormality' some 'CBL Gene Mutation') and ('Disease_May_Have_Associated_Disease' some 'Juvenile Myelomonocytic Leukemia Associated with Noonan Syndrome-Like Disorder') and ('Disease_Has_Associated_Disease' some 'Developmental Delay') and ('Disease_Has_Associated_Disease' some 'Congenital Heart Disease') and ('Disease_Mapped_To_Gene' some 'CBL Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198720</classIRI>
<classLabel>Artistic, Cultural and Culinary Associate Professional</classLabel>
<newAxiom>'Artistic, Cultural and Culinary Associate Professional' SubClassOf 'Occupation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198722</classIRI>
<classLabel>Author, Journalist and Linguist</classLabel>
<newAxiom>'Author, Journalist and Linguist' SubClassOf 'Media and Communication Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198721</classIRI>
<classLabel>Assembler</classLabel>
<newAxiom>'Assembler' SubClassOf 'Assemblers and Fabricators'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198724</classIRI>
<classLabel>Building and Housekeeping Supervisor</classLabel>
<newAxiom>'Building and Housekeeping Supervisor' SubClassOf 'Construction Trades Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198723</classIRI>
<classLabel>Blacksmith, Toolmaker and Related Trades Worker</classLabel>
<newAxiom>'Blacksmith, Toolmaker and Related Trades Worker' SubClassOf 'Other Construction and Related Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198726</classIRI>
<classLabel>Building Frame and Related Trades Worker</classLabel>
<newAxiom>'Building Frame and Related Trades Worker' SubClassOf 'Construction Trades Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198725</classIRI>
<classLabel>Building Finisher and Related Trades Worker</classLabel>
<newAxiom>'Building Finisher and Related Trades Worker' SubClassOf 'Supervisors, Building and Grounds Cleaning and Maintenance Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198728</classIRI>
<classLabel>Business Services and Administration Manager</classLabel>
<newAxiom>'Business Services and Administration Manager' SubClassOf 'Business and Financial Operations Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198727</classIRI>
<classLabel>Business Services Agent</classLabel>
<newAxiom>'Business Services Agent' SubClassOf 'Business and Financial Operations Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198729</classIRI>
<classLabel>Car, Van and Motorcycle Driver</classLabel>
<newAxiom>'Car, Van and Motorcycle Driver' SubClassOf 'Transportation and Material Moving Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198731</classIRI>
<classLabel>Chemical and Photographic Products Plant and Machine Operator</classLabel>
<newAxiom>'Chemical and Photographic Products Plant and Machine Operator' SubClassOf 'Plant and System Operators'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198730</classIRI>
<classLabel>Cashier and Ticket Clerk</classLabel>
<newAxiom>'Cashier and Ticket Clerk' SubClassOf 'Clerk'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198733</classIRI>
<classLabel>Client Information Worker</classLabel>
<newAxiom>'Client Information Worker' SubClassOf 'Office and Administrative Support Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198732</classIRI>
<classLabel>Child Care Worker and Teachers' Aide</classLabel>
<newAxiom>'Child Care Worker and Teachers' Aide' SubClassOf 'Other Teachers and Instructors'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198735</classIRI>
<classLabel>Database and Network Professional</classLabel>
<newAxiom>'Database and Network Professional' SubClassOf 'Computer Specialists'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198734</classIRI>
<classLabel>Commissioned Armed Forces Officer</classLabel>
<newAxiom>'Commissioned Armed Forces Officer' SubClassOf 'Military Occupation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198737</classIRI>
<classLabel>Electronics and Telecommunications Installer and Repairer</classLabel>
<newAxiom>'Electronics and Telecommunications Installer and Repairer' SubClassOf 'Electrical and Electronic Equipment Mechanics, Installers, and Repairers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198736</classIRI>
<classLabel>Domestic, Hotel and Office Cleaner and Helper</classLabel>
<newAxiom>'Domestic, Hotel and Office Cleaner and Helper' SubClassOf 'Building and Grounds Cleaning and Maintenance Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198739</classIRI>
<classLabel>Financial and Mathematical Associate Professional</classLabel>
<newAxiom>'Financial and Mathematical Associate Professional' SubClassOf 'Financial Specialists'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198738</classIRI>
<classLabel>Electrotechnology Engineer</classLabel>
<newAxiom>'Electrotechnology Engineer' SubClassOf 'Engineers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198740</classIRI>
<classLabel>Fishery Worker, Hunter and Trapper</classLabel>
<newAxiom>'Fishery Worker, Hunter and Trapper' SubClassOf 'Fishing and Hunting Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198742</classIRI>
<classLabel>Food Preparation Assistant</classLabel>
<newAxiom>'Food Preparation Assistant' SubClassOf 'Cooks and Food Preparation Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198741</classIRI>
<classLabel>Food and Related Products Machine Operator</classLabel>
<newAxiom>'Food and Related Products Machine Operator' SubClassOf 'Cooks and Food Preparation Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198744</classIRI>
<classLabel>Forestry and Related Worker</classLabel>
<newAxiom>'Forestry and Related Worker' SubClassOf 'Forest, Conservation, and Logging Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198743</classIRI>
<classLabel>Food Processing and Related Trades Worker</classLabel>
<newAxiom>'Food Processing and Related Trades Worker' SubClassOf 'Cooks and Food Preparation Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198746</classIRI>
<classLabel>General Office Clerk</classLabel>
<newAxiom>'General Office Clerk' SubClassOf 'Clerk'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198745</classIRI>
<classLabel>Garment and Related Trades Worker</classLabel>
<newAxiom>'Garment and Related Trades Worker' SubClassOf 'Textile, Apparel, and Furnishings Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198748</classIRI>
<classLabel>Hairdresser, Beautician and Related Worker</classLabel>
<newAxiom>'Hairdresser, Beautician and Related Worker' SubClassOf 'Personal Appearance Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198747</classIRI>
<classLabel>Government Regulatory Associate Professional</classLabel>
<newAxiom>'Government Regulatory Associate Professional' SubClassOf 'Occupation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198749</classIRI>
<classLabel>Handicraft Worker</classLabel>
<newAxiom>'Handicraft Worker' SubClassOf 'Artist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198751</classIRI>
<classLabel>Hotel and Restaurant Manager</classLabel>
<newAxiom>'Hotel and Restaurant Manager' SubClassOf 'Manager'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198750</classIRI>
<classLabel>Heavy Truck and Bus Driver</classLabel>
<newAxiom>'Heavy Truck and Bus Driver' SubClassOf 'Transportation and Material Moving Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198753</classIRI>
<classLabel>Information and Communications Technology Service Manager</classLabel>
<newAxiom>'Information and Communications Technology Service Manager' SubClassOf 'Media and Communication Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198752</classIRI>
<classLabel>Information and Communications Technology Operations and User Support Technician</classLabel>
<newAxiom>'Information and Communications Technology Operations and User Support Technician' SubClassOf 'Media and Communication Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198755</classIRI>
<classLabel>Legislator and Senior Official</classLabel>
<newAxiom>'Legislator and Senior Official' SubClassOf 'Legal Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198754</classIRI>
<classLabel>Keyboard Operator</classLabel>
<newAxiom>'Keyboard Operator' SubClassOf 'Clerk'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198757</classIRI>
<classLabel>Locomotive Engine Driver and Related Worker</classLabel>
<newAxiom>'Locomotive Engine Driver and Related Worker' SubClassOf 'Transportation and Material Moving Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198756</classIRI>
<classLabel>Life Science Technician and Related Associate Professional</classLabel>
<newAxiom>'Life Science Technician and Related Associate Professional' SubClassOf 'Life, Physical, and Social Science Technicians'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198759</classIRI>
<classLabel>Managing Director and Chief Executive</classLabel>
<newAxiom>'Managing Director and Chief Executive' SubClassOf 'Manager'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198758</classIRI>
<classLabel>Machinery Mechanics and Repairer</classLabel>
<newAxiom>'Machinery Mechanics and Repairer' SubClassOf 'Occupation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198760</classIRI>
<classLabel>Manufacturing, Mining, Construction and Distribution Manager</classLabel>
<newAxiom>'Manufacturing, Mining, Construction and Distribution Manager' SubClassOf 'Manager'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198762</classIRI>
<classLabel>Material Recording and Transport Clerk</classLabel>
<newAxiom>'Material Recording and Transport Clerk' SubClassOf 'Clerk'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198761</classIRI>
<classLabel>Market Gardener and Crop Grower</classLabel>
<newAxiom>'Market Gardener and Crop Grower' SubClassOf 'Farmer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198764</classIRI>
<classLabel>Medical and Pharmaceutical Technician</classLabel>
<newAxiom>'Medical and Pharmaceutical Technician' SubClassOf 'Allied Health Profession'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198763</classIRI>
<classLabel>Mathematician, Actuary and Statistician</classLabel>
<newAxiom>'Mathematician, Actuary and Statistician' SubClassOf 'Mathematical Science Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198766</classIRI>
<classLabel>Mining and Construction Laborer</classLabel>
<newAxiom>'Mining and Construction Laborer' SubClassOf 'Construction and Extraction Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198765</classIRI>
<classLabel>Metal Processing and Finishing Plant Operator</classLabel>
<newAxiom>'Metal Processing and Finishing Plant Operator' SubClassOf 'Metal Workers and Plastic Workers'</newAxiom>
<newAxiom>'Metal Processing and Finishing Plant Operator' SubClassOf 'Plant and System Operators'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198768</classIRI>
<classLabel>Mining, Manufacturing and Construction Supervisor</classLabel>
<newAxiom>'Mining, Manufacturing and Construction Supervisor' SubClassOf 'Supervisors, Construction and Extraction Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198767</classIRI>
<classLabel>Mining and Mineral Processing Plant Operator</classLabel>
<newAxiom>'Mining and Mineral Processing Plant Operator' SubClassOf 'Construction and Extraction Occupations'</newAxiom>
<newAxiom>'Mining and Mineral Processing Plant Operator' SubClassOf 'Plant and System Operators'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198769</classIRI>
<classLabel>Mixed Crop and Animal Producer</classLabel>
<newAxiom>'Mixed Crop and Animal Producer' SubClassOf 'Farming, Fishing, and Forestry Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198771</classIRI>
<classLabel>Non-commissioned Armed Forces Officer</classLabel>
<newAxiom>'Non-commissioned Armed Forces Officer' SubClassOf 'Military Occupation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198770</classIRI>
<classLabel>Mobile Plant Operator</classLabel>
<newAxiom>'Mobile Plant Operator' SubClassOf 'Transportation and Material Moving Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198773</classIRI>
<classLabel>Nursing and Midwifery Associate Professional</classLabel>
<newAxiom>'Nursing and Midwifery Associate Professional' SubClassOf 'Medical Occupation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198772</classIRI>
<classLabel>Numerical Clerk</classLabel>
<newAxiom>'Numerical Clerk' SubClassOf 'Clerk'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198775</classIRI>
<classLabel>Other Clerical Support Worker</classLabel>
<newAxiom>'Other Clerical Support Worker' SubClassOf 'Clerk'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198774</classIRI>
<classLabel>Nursing and Midwifery Professional</classLabel>
<newAxiom>'Nursing and Midwifery Professional' SubClassOf 'Medical Occupation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198777</classIRI>
<classLabel>Other Elementary Worker</classLabel>
<newAxiom>'Other Elementary Worker' SubClassOf 'Occupation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198776</classIRI>
<classLabel>Other Craft and Related Worker</classLabel>
<newAxiom>'Other Craft and Related Worker' SubClassOf 'Artist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198779</classIRI>
<classLabel>Other Health Professional</classLabel>
<newAxiom>'Other Health Professional' SubClassOf 'Health Care Professional'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198778</classIRI>
<classLabel>Other Health Associate Professional</classLabel>
<newAxiom>'Other Health Associate Professional' SubClassOf 'Allied Health Profession'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198780</classIRI>
<classLabel>Other Personal Services Worker</classLabel>
<newAxiom>'Other Personal Services Worker' SubClassOf 'Personal Care and Service Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198782</classIRI>
<classLabel>Other Stationary Plant and Machine Operator</classLabel>
<newAxiom>'Other Stationary Plant and Machine Operator' SubClassOf 'Equipment Operator'</newAxiom>
<newAxiom>'Other Stationary Plant and Machine Operator' SubClassOf 'Plant and System Operators'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198781</classIRI>
<classLabel>Other Services Manager</classLabel>
<newAxiom>'Other Services Manager' SubClassOf 'Manager'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198784</classIRI>
<classLabel>Personal Care Workers in Health Service</classLabel>
<newAxiom>'Personal Care Workers in Health Service' SubClassOf 'Personal Care and Service Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198783</classIRI>
<classLabel>Painter, Building Structure Cleaner and Related Trades Worker</classLabel>
<newAxiom>'Painter, Building Structure Cleaner and Related Trades Worker' SubClassOf 'Building and Grounds Cleaning and Maintenance Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198786</classIRI>
<classLabel>Physical and Engineering Science Technician</classLabel>
<newAxiom>'Physical and Engineering Science Technician' SubClassOf 'Physical Scientists'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198785</classIRI>
<classLabel>Physical and Earth Science Professional</classLabel>
<newAxiom>'Physical and Earth Science Professional' SubClassOf 'Physical Scientists'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198788</classIRI>
<classLabel>Process Control Technician</classLabel>
<newAxiom>'Process Control Technician' SubClassOf 'Equipment Operator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198787</classIRI>
<classLabel>Primary School and Early Childhood Teacher</classLabel>
<newAxiom>'Primary School and Early Childhood Teacher' SubClassOf 'Teacher'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198789</classIRI>
<classLabel>Production Manager in Agriculture, Forestry and Fishery</classLabel>
<newAxiom>'Production Manager in Agriculture, Forestry and Fishery' SubClassOf 'Manager'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198791</classIRI>
<classLabel>Refuse Worker</classLabel>
<newAxiom>'Refuse Worker' SubClassOf 'Occupation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198790</classIRI>
<classLabel>Professional Services Manager</classLabel>
<newAxiom>'Professional Services Manager' SubClassOf 'Manager'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198793</classIRI>
<classLabel>Rubber, Plastic and Paper Products Machine Operator</classLabel>
<newAxiom>'Rubber, Plastic and Paper Products Machine Operator' SubClassOf 'Equipment Operator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198792</classIRI>
<classLabel>Retail and Wholesale Trade Manager</classLabel>
<newAxiom>'Retail and Wholesale Trade Manager' SubClassOf 'Manager'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198795</classIRI>
<classLabel>Sales, Marketing and Development Manager</classLabel>
<newAxiom>'Sales, Marketing and Development Manager' SubClassOf 'Manager'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198794</classIRI>
<classLabel>Sales and Purchasing Agent and Broker</classLabel>
<newAxiom>'Sales and Purchasing Agent and Broker' SubClassOf 'Sales and Related Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198797</classIRI>
<classLabel>Secondary Education Teacher</classLabel>
<newAxiom>'Secondary Education Teacher' SubClassOf 'Teacher'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198796</classIRI>
<classLabel>Sales, Marketing and Public Relations Professional</classLabel>
<newAxiom>'Sales, Marketing and Public Relations Professional' SubClassOf 'Sales and Related Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198799</classIRI>
<classLabel>Sheet and Structural Metal Worker, Molder and Welder, and Related Worker</classLabel>
<newAxiom>'Sheet and Structural Metal Worker, Molder and Welder, and Related Worker' SubClassOf 'Trades, Transport, or Construction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198798</classIRI>
<classLabel>Secretary (General)</classLabel>
<newAxiom>'Secretary (General)' SubClassOf 'Secretaries and Administrative Assistants'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198700</classIRI>
<classLabel>Cytomegalovirus End-Organ Disease</classLabel>
<newAxiom>'Cytomegalovirus End-Organ Disease' SubClassOf 'Cytomegaloviral Infection'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198702</classIRI>
<classLabel>Modified Interleukin-2 LTC004</classLabel>
<newAxiom>'Modified Interleukin-2 LTC004' SubClassOf 'Recombinant Interleukin-2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198701</classIRI>
<classLabel>Anti-DLL3 Bispecific Antibody RO7616789</classLabel>
<newAxiom>'Anti-DLL3 Bispecific Antibody RO7616789' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-DLL3 Bispecific Antibody RO7616789' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198704</classIRI>
<classLabel>Cytomegalovirus DNA Positive</classLabel>
<newAxiom>'Cytomegalovirus DNA Positive' SubClassOf 'Positive Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198703</classIRI>
<classLabel>Ventriculitis</classLabel>
<newAxiom>'Ventriculitis' SubClassOf 'Non-Neoplastic Brain Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198706</classIRI>
<classLabel>Advanced Endometrial Undifferentiated Carcinoma</classLabel>
<newAxiom>'Advanced Endometrial Undifferentiated Carcinoma' EquivalentTo 'Advanced Endometrial Carcinoma' and 'Metastatic Endometrial Undifferentiated Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198705</classIRI>
<classLabel>Metastatic Endometrial Undifferentiated Carcinoma</classLabel>
<newAxiom>'Metastatic Endometrial Undifferentiated Carcinoma' EquivalentTo 'Metastatic Endometrial Carcinoma' and 'Endometrial Undifferentiated Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198708</classIRI>
<classLabel>Gemcitabine/Pazopanib Regimen</classLabel>
<newAxiom>'Gemcitabine/Pazopanib Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Pazopanib Hydrochloride'</newAxiom>
<newAxiom>'Gemcitabine/Pazopanib Regimen' SubClassOf 'Regimen Used to Treat Malignant Soft Tissue Neoplasm'</newAxiom>
<newAxiom>'Gemcitabine/Pazopanib Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Gemcitabine Hydrochloride'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198707</classIRI>
<classLabel>Bexarotene/Peginterferon Alfa-2a Regimen</classLabel>
<newAxiom>'Bexarotene/Peginterferon Alfa-2a Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Peginterferon Alfa-2a'</newAxiom>
<newAxiom>'Bexarotene/Peginterferon Alfa-2a Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Bexarotene'</newAxiom>
<newAxiom>'Bexarotene/Peginterferon Alfa-2a Regimen' SubClassOf 'Regimen Used to Treat Non-Hodgkin Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198709</classIRI>
<classLabel>Streptozocin Regimen</classLabel>
<newAxiom>'Streptozocin Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Streptozocin'</newAxiom>
<newAxiom>'Streptozocin Regimen' SubClassOf 'Regimen Used to Treat Malignant Neuroendocrine and Adrenal Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198711</classIRI>
<classLabel>CBL-B Inhibitor HST-1011</classLabel>
<newAxiom>'CBL-B Inhibitor HST-1011' SubClassOf 'Immunotherapeutic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198710</classIRI>
<classLabel>FAS Regimen</classLabel>
<newAxiom>'FAS Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Doxorubicin'</newAxiom>
<newAxiom>'FAS Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Streptozocin'</newAxiom>
<newAxiom>'FAS Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Fluorouracil'</newAxiom>
<newAxiom>'FAS Regimen' SubClassOf 'Regimen Used to Treat Malignant Neuroendocrine and Adrenal Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198713</classIRI>
<classLabel>Oxidative DNA Damage</classLabel>
<newAxiom>'Oxidative DNA Damage' SubClassOf 'DNA Damage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198712</classIRI>
<classLabel>Mouth Rinse Specimen</classLabel>
<newAxiom>'Mouth Rinse Specimen' SubClassOf 'Lavage Fluid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198715</classIRI>
<classLabel>Administration Professional</classLabel>
<newAxiom>'Administration Professional' SubClassOf 'Management Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198714</classIRI>
<classLabel>Experimental Surgical Procedure</classLabel>
<newAxiom>'Experimental Surgical Procedure' SubClassOf 'Experimental Therapeutic Procedure'</newAxiom>
<newAxiom>'Experimental Surgical Procedure' SubClassOf 'Surgical Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198717</classIRI>
<classLabel>Animal Producer</classLabel>
<newAxiom>'Animal Producer' SubClassOf 'Animal Care and Service Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198716</classIRI>
<classLabel>Administrative and Specialized Secretary</classLabel>
<newAxiom>'Administrative and Specialized Secretary' SubClassOf 'Office and Administrative Support Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198719</classIRI>
<classLabel>Armed Forces Occupation, Other Rank</classLabel>
<newAxiom>'Armed Forces Occupation, Other Rank' SubClassOf 'Military Occupation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198718</classIRI>
<classLabel>Architect, Planner, Surveyor and Designer</classLabel>
<newAxiom>'Architect, Planner, Surveyor and Designer' SubClassOf 'Architects, Surveyors, and Cartographers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198841</classIRI>
<classLabel>Acute Myeloid Leukemia with BCOR-RARA</classLabel>
<newAxiom>'Acute Myeloid Leukemia with BCOR-RARA' EquivalentTo 'Acute Myeloid Leukemia with a Variant RARA Rearrangement' and ('Disease_Has_Molecular_Abnormality' some 'BCOR-RARA Fusion Protein Expression') and ('Disease_Mapped_To_Gene' some 'BCOR/RARA Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198840</classIRI>
<classLabel>BCOR-RARA Fusion Protein Expression</classLabel>
<newAxiom>'BCOR-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'BCOR Gene'</newAxiom>
<newAxiom>'BCOR-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'BCOR/RARA Fusion Gene'</newAxiom>
<newAxiom>'BCOR-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'RARA Gene'</newAxiom>
<newAxiom>'BCOR-RARA Fusion Protein Expression' SubClassOf 'Fusion Protein Expression'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198843</classIRI>
<classLabel>Photoplethysmography</classLabel>
<newAxiom>'Photoplethysmography' SubClassOf 'Diagnostic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198842</classIRI>
<classLabel>TTK/PLK1 Inhibitor BAL0891</classLabel>
<newAxiom>'TTK/PLK1 Inhibitor BAL0891' SubClassOf 'PLK1 Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198845</classIRI>
<classLabel>Distal GATA2 Enhancer Repositioning</classLabel>
<newAxiom>'Distal GATA2 Enhancer Repositioning' SubClassOf 'Rearrangement Detected'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198844</classIRI>
<classLabel>t(3;8)(q26.2;q24)</classLabel>
<newAxiom>'t(3;8)(q26.2;q24)' SubClassOf 'C-Myc Translocation'</newAxiom>
<newAxiom>'t(3;8)(q26.2;q24)' SubClassOf 'MECOM Gene Rearrangement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198847</classIRI>
<classLabel>Acute Myeloid Leukemia with t(3;8)(q26.2;q24); MYC, MECOM</classLabel>
<newAxiom>'Acute Myeloid Leukemia with t(3;8)(q26.2;q24); MYC, MECOM' EquivalentTo 'Acute Myeloid Leukemia with a Variant MECOM Rearrangement' and ('Disease_Has_Cytogenetic_Abnormality' some 't(3;8)(q26.2;q24)')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198846</classIRI>
<classLabel>Acute Myeloid Leukemia with a Variant MECOM Rearrangement</classLabel>
<newAxiom>'Acute Myeloid Leukemia with a Variant MECOM Rearrangement' EquivalentTo 'Acute Myeloid Leukemia with Recurrent Genetic Abnormalities' and ('Disease_Has_Cytogenetic_Abnormality' some 'MECOM Gene Rearrangement') and ('Disease_Excludes_Finding' some 'Distal GATA2 Enhancer Repositioning') and ('Disease_Mapped_To_Gene' some 'MECOM Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198849</classIRI>
<classLabel>Acute Myeloid Leukemia with t(3;12)(q26.2;p13.2); ETV6-MECOM</classLabel>
<newAxiom>'Acute Myeloid Leukemia with t(3;12)(q26.2;p13.2); ETV6-MECOM' EquivalentTo 'Acute Myeloid Leukemia with a Variant MECOM Rearrangement' and ('Disease_Has_Cytogenetic_Abnormality' some 't(3;12)(q26.2;p13.2)') and ('Disease_Mapped_To_Gene' some 'ETV6/MECOM Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198848</classIRI>
<classLabel>t(3;12)(q26.2;p13.2)</classLabel>
<newAxiom>'t(3;12)(q26.2;p13.2)' SubClassOf 'MECOM Gene Rearrangement'</newAxiom>
<newAxiom>'t(3;12)(q26.2;p13.2)' SubClassOf 'Chromosomal Translocation'</newAxiom>
<newAxiom>'t(3;12)(q26.2;p13.2)' SubClassOf 'ETV6 Gene Rearrangement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198850</classIRI>
<classLabel>Acute Myeloid Leukemia with t(3;21)(q26.2;q22.1); MECOM-RUNX1</classLabel>
<newAxiom>'Acute Myeloid Leukemia with t(3;21)(q26.2;q22.1); MECOM-RUNX1' EquivalentTo 'Acute Myeloid Leukemia with a Variant MECOM Rearrangement' and ('Disease_Has_Molecular_Abnormality' some 'MECOM-RUNX1 Fusion Protein Expression') and ('Disease_Has_Cytogenetic_Abnormality' some 't(3;21)(q26;q22)') and ('Disease_Mapped_To_Gene' some 'RUNX1/MECOM Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198852</classIRI>
<classLabel>BCOR/RARA Fusion Protein</classLabel>
<newAxiom>'BCOR/RARA Fusion Protein' SubClassOf 'Fusion Protein'</newAxiom>
<newAxiom>'BCOR/RARA Fusion Protein' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'BCOR/RARA Fusion Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198851</classIRI>
<classLabel>BCOR/RARA Fusion Gene</classLabel>
<newAxiom>'BCOR/RARA Fusion Gene' SubClassOf 'Gene_Involved_In_Pathogenesis_Of_Disease' some 'Acute Myeloid Leukemia with BCOR-RARA'</newAxiom>
<newAxiom>'BCOR/RARA Fusion Gene' SubClassOf 'Fusion Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198854</classIRI>
<classLabel>FIP1L1/RARA Fusion Protein</classLabel>
<newAxiom>'FIP1L1/RARA Fusion Protein' SubClassOf 'Fusion Protein'</newAxiom>
<newAxiom>'FIP1L1/RARA Fusion Protein' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'FIP1L1/RARA Fusion Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198853</classIRI>
<classLabel>FIP1L1/RARA Fusion Gene</classLabel>
<newAxiom>'FIP1L1/RARA Fusion Gene' SubClassOf 'Fusion Gene'</newAxiom>
<newAxiom>'FIP1L1/RARA Fusion Gene' SubClassOf 'Gene_Involved_In_Pathogenesis_Of_Disease' some 'Acute Myeloid Leukemia with FIP1L1-RARA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198856</classIRI>
<classLabel>IRF2BP2/RARA Fusion Protein</classLabel>
<newAxiom>'IRF2BP2/RARA Fusion Protein' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'IRF2BP2/RARA Fusion Gene'</newAxiom>
<newAxiom>'IRF2BP2/RARA Fusion Protein' SubClassOf 'Fusion Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198855</classIRI>
<classLabel>IRF2BP2/RARA Fusion Gene</classLabel>
<newAxiom>'IRF2BP2/RARA Fusion Gene' SubClassOf 'Gene_Involved_In_Pathogenesis_Of_Disease' some 'Acute Myeloid Leukemia with t(1;17)(q42.3;q21.2); IRF2BP2-RARA'</newAxiom>
<newAxiom>'IRF2BP2/RARA Fusion Gene' SubClassOf 'Fusion Gene'</newAxiom>
<newAxiom>'IRF2BP2/RARA Fusion Gene' SubClassOf 'Gene_Has_Abnormality' some 't(1;17)(q42.3;q21.2)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198858</classIRI>
<classLabel>TBL1XR1/RARA Fusion Protein</classLabel>
<newAxiom>'TBL1XR1/RARA Fusion Protein' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'TBL1XR1/RARA Fusion Gene'</newAxiom>
<newAxiom>'TBL1XR1/RARA Fusion Protein' SubClassOf 'Fusion Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198857</classIRI>
<classLabel>TBL1XR1/RARA Fusion Gene</classLabel>
<newAxiom>'TBL1XR1/RARA Fusion Gene' SubClassOf 'Gene_Involved_In_Pathogenesis_Of_Disease' some 'Acute Myeloid Leukemia with TBL1XR1-RARA'</newAxiom>
<newAxiom>'TBL1XR1/RARA Fusion Gene' SubClassOf 'Fusion Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198859</classIRI>
<classLabel>Anti-CD19 Antibody-drug Conjugate</classLabel>
<newAxiom>'Anti-CD19 Antibody-drug Conjugate' SubClassOf 'CD19-targeting Agent'</newAxiom>
<newAxiom>'Anti-CD19 Antibody-drug Conjugate' SubClassOf 'Immunoconjugate'</newAxiom>
<newAxiom>'Anti-CD19 Antibody-drug Conjugate' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198861</classIRI>
<classLabel>Acute Myeloid Leukemia with t(4;11)(q21.3;q23.3); AFF1-KMT2A</classLabel>
<newAxiom>'Acute Myeloid Leukemia with t(4;11)(q21.3;q23.3); AFF1-KMT2A' EquivalentTo 'Acute Myeloid Leukemia with a Variant KMT2A Rearrangement' and ('Disease_Has_Molecular_Abnormality' some 'KMT2A-AFF1 Fusion Protein Expression') and ('Disease_Has_Cytogenetic_Abnormality' some 't(4;11)(q21;q23)') and ('Disease_Mapped_To_Gene' some 'MLL/AFF1 Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198860</classIRI>
<classLabel>VEGF-targeting Agent</classLabel>
<newAxiom>'VEGF-targeting Agent' SubClassOf 'Targeted Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198863</classIRI>
<classLabel>RAPNO Tumor Response Criteria</classLabel>
<newAxiom>'RAPNO Tumor Response Criteria' SubClassOf 'Tumor Response System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198862</classIRI>
<classLabel>Modified Macdonald Tumor Response Criteria</classLabel>
<newAxiom>'Modified Macdonald Tumor Response Criteria' SubClassOf 'Tumor Response System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198865</classIRI>
<classLabel>International Neuroblastoma Response Criteria, Brodeur 1993</classLabel>
<newAxiom>'International Neuroblastoma Response Criteria, Brodeur 1993' SubClassOf 'International Neuroblastoma Response Criteria'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198864</classIRI>
<classLabel>International Neuroblastoma Response Criteria, Park 2017</classLabel>
<newAxiom>'International Neuroblastoma Response Criteria, Park 2017' SubClassOf 'International Neuroblastoma Response Criteria'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198867</classIRI>
<classLabel>t(10;11)(q21.3;q23.3)</classLabel>
<newAxiom>'t(10;11)(q21.3;q23.3)' SubClassOf 'TET1 Gene Rearrangement'</newAxiom>
<newAxiom>'t(10;11)(q21.3;q23.3)' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'KMT2A/TET1 Fusion Gene'</newAxiom>
<newAxiom>'t(10;11)(q21.3;q23.3)' SubClassOf 'KMT2A Gene Translocation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198866</classIRI>
<classLabel>Age at Stem Cell Harvest</classLabel>
<newAxiom>'Age at Stem Cell Harvest' SubClassOf 'Age'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198869</classIRI>
<classLabel>Acute Myeloid Leukemia with t(10;11)(q21.3;q23.3); TET1-KMT2A</classLabel>
<newAxiom>'Acute Myeloid Leukemia with t(10;11)(q21.3;q23.3); TET1-KMT2A' EquivalentTo 'Acute Myeloid Leukemia with a Variant KMT2A Rearrangement' and ('Disease_Has_Molecular_Abnormality' some 'TET1-KMT2A Fusion Protein Expression') and ('Disease_Has_Cytogenetic_Abnormality' some 't(10;11)(q21.3;q23.3)') and ('Disease_Mapped_To_Gene' some 'KMT2A/TET1 Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198868</classIRI>
<classLabel>TET1-KMT2A Fusion Protein Expression</classLabel>
<newAxiom>'TET1-KMT2A Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'KMT2A/TET1 Fusion Gene'</newAxiom>
<newAxiom>'TET1-KMT2A Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'TET1 Gene'</newAxiom>
<newAxiom>'TET1-KMT2A Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'KMT2A Gene'</newAxiom>
<newAxiom>'TET1-KMT2A Fusion Protein Expression' SubClassOf 'Fusion Protein Expression'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198870</classIRI>
<classLabel>Acute Myeloid Leukemia with t(11;19)(q23.3;p13.1); KMT2A-ELL</classLabel>
<newAxiom>'Acute Myeloid Leukemia with t(11;19)(q23.3;p13.1); KMT2A-ELL' EquivalentTo 'Acute Myeloid Leukemia with a Variant KMT2A Rearrangement' and ('Disease_Has_Molecular_Abnormality' some 'KMT2A-ELL Fusion Protein Expression') and ('Disease_Has_Cytogenetic_Abnormality' some 't(11;19)(q23.3;p13.1)') and ('Disease_Mapped_To_Gene' some 'MLL/ELL Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198872</classIRI>
<classLabel>KMT2A/TET1 Fusion Protein</classLabel>
<newAxiom>'KMT2A/TET1 Fusion Protein' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'KMT2A/TET1 Fusion Gene'</newAxiom>
<newAxiom>'KMT2A/TET1 Fusion Protein' SubClassOf 'Fusion Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198871</classIRI>
<classLabel>KMT2A/TET1 Fusion Gene</classLabel>
<newAxiom>'KMT2A/TET1 Fusion Gene' SubClassOf 'Fusion Gene'</newAxiom>
<newAxiom>'KMT2A/TET1 Fusion Gene' SubClassOf 'Gene_Has_Abnormality' some 't(10;11)(q21.3;q23.3)'</newAxiom>
<newAxiom>'KMT2A/TET1 Fusion Gene' SubClassOf 'Gene_Involved_In_Pathogenesis_Of_Disease' some 'Acute Myeloid Leukemia with t(10;11)(q21.3;q23.3); TET1-KMT2A'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198874</classIRI>
<classLabel>Acute Myeloid Leukemia with t(11;19)(q23.3;p13.3); KMT2A-MLLT1</classLabel>
<newAxiom>'Acute Myeloid Leukemia with t(11;19)(q23.3;p13.3); KMT2A-MLLT1' EquivalentTo 'Acute Myeloid Leukemia with a Variant KMT2A Rearrangement' and ('Disease_Has_Molecular_Abnormality' some 'KMT2A-MLLT1 Fusion Protein Expression') and ('Disease_Has_Cytogenetic_Abnormality' some 't(11;19)(q23.3;p13.3)') and ('Disease_Mapped_To_Gene' some 'MLL/MLLT1 Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198873</classIRI>
<classLabel>mFOLFOX6-Pembrolizumab Regimen</classLabel>
<newAxiom>'mFOLFOX6-Pembrolizumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Oxaliplatin'</newAxiom>
<newAxiom>'mFOLFOX6-Pembrolizumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Leucovorin Calcium'</newAxiom>
<newAxiom>'mFOLFOX6-Pembrolizumab Regimen' SubClassOf 'Regimen Used to Treat Esophageal Carcinoma'</newAxiom>
<newAxiom>'mFOLFOX6-Pembrolizumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Fluorouracil'</newAxiom>
<newAxiom>'mFOLFOX6-Pembrolizumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Pembrolizumab'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198876</classIRI>
<classLabel>CMV Pentamer Complex Proteins/gB-encoding mRNA Vaccine mRNA-1647</classLabel>
<newAxiom>'CMV Pentamer Complex Proteins/gB-encoding mRNA Vaccine mRNA-1647' SubClassOf 'mRNA Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198875</classIRI>
<classLabel>Human Cytomegalovirus Envelope Glycoprotein B Immunoglobulin G</classLabel>
<newAxiom>'Human Cytomegalovirus Envelope Glycoprotein B Immunoglobulin G' SubClassOf 'IgG'</newAxiom>
<newAxiom>'Human Cytomegalovirus Envelope Glycoprotein B Immunoglobulin G' SubClassOf 'Cytomegalovirus Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198878</classIRI>
<classLabel>Anti-CD19/CD20 Bicistronic CAR T-cells</classLabel>
<newAxiom>'Anti-CD19/CD20 Bicistronic CAR T-cells' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Anti-CD19/CD20 Bicistronic CAR T-cells' SubClassOf 'Anti-CD19-targeting CAR-T Cells'</newAxiom>
<newAxiom>'Anti-CD19/CD20 Bicistronic CAR T-cells' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198877</classIRI>
<classLabel>Human Cytomegalovirus Envelope Pentamer Immunoglobulin G</classLabel>
<newAxiom>'Human Cytomegalovirus Envelope Pentamer Immunoglobulin G' SubClassOf 'IgG'</newAxiom>
<newAxiom>'Human Cytomegalovirus Envelope Pentamer Immunoglobulin G' SubClassOf 'Cytomegalovirus Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198879</classIRI>
<classLabel>Intravesical Docetaxel Regimen</classLabel>
<newAxiom>'Intravesical Docetaxel Regimen' SubClassOf 'Regimen Used to Treat Bladder Carcinoma'</newAxiom>
<newAxiom>'Intravesical Docetaxel Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Docetaxel'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198881</classIRI>
<classLabel>Docetaxel/Fluorouracil/Oxaliplatin Regimen</classLabel>
<newAxiom>'Docetaxel/Fluorouracil/Oxaliplatin Regimen' SubClassOf 'Regimen Used to Treat Esophageal Carcinoma'</newAxiom>
<newAxiom>'Docetaxel/Fluorouracil/Oxaliplatin Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Oxaliplatin'</newAxiom>
<newAxiom>'Docetaxel/Fluorouracil/Oxaliplatin Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Docetaxel'</newAxiom>
<newAxiom>'Docetaxel/Fluorouracil/Oxaliplatin Regimen' SubClassOf 'Regimen Used to Treat Gastric Carcinoma'</newAxiom>
<newAxiom>'Docetaxel/Fluorouracil/Oxaliplatin Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Fluorouracil'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198880</classIRI>
<classLabel>Docetaxel/Irinotecan Regimen</classLabel>
<newAxiom>'Docetaxel/Irinotecan Regimen' SubClassOf 'Regimen Used to Treat Gastric Carcinoma'</newAxiom>
<newAxiom>'Docetaxel/Irinotecan Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Irinotecan'</newAxiom>
<newAxiom>'Docetaxel/Irinotecan Regimen' SubClassOf 'Regimen Used to Treat Esophageal Carcinoma'</newAxiom>
<newAxiom>'Docetaxel/Irinotecan Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Docetaxel'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198801</classIRI>
<classLabel>Ships' Deck Crew and Related Worker</classLabel>
<newAxiom>'Ships' Deck Crew and Related Worker' SubClassOf 'Transportation and Material Moving Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198800</classIRI>
<classLabel>Ship and Aircraft Controller and Technician</classLabel>
<newAxiom>'Ship and Aircraft Controller and Technician' SubClassOf 'Transportation and Material Moving Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198803</classIRI>
<classLabel>Software and Applications Developer and Analyst</classLabel>
<newAxiom>'Software and Applications Developer and Analyst' SubClassOf 'Computer and Mathematical Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198802</classIRI>
<classLabel>Social and Religious Professional</classLabel>
<newAxiom>'Social and Religious Professional' SubClassOf 'Religious Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198805</classIRI>
<classLabel>Street and Market Salesperson</classLabel>
<newAxiom>'Street and Market Salesperson' SubClassOf 'Sales and Related Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198804</classIRI>
<classLabel>Sports and Fitness Worker</classLabel>
<newAxiom>'Sports and Fitness Worker' SubClassOf 'Personal Care and Service Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198807</classIRI>
<classLabel>Street Vendor (Excluding Food)</classLabel>
<newAxiom>'Street Vendor (Excluding Food)' SubClassOf 'Sales and Related Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198806</classIRI>
<classLabel>Street and Related Service Worker</classLabel>
<newAxiom>'Street and Related Service Worker' SubClassOf 'Personal Care and Service Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198809</classIRI>
<classLabel>Subsistence Fisherman, Hunter, Trapper and Gatherer</classLabel>
<newAxiom>'Subsistence Fisherman, Hunter, Trapper and Gatherer' SubClassOf 'Fishing and Hunting Workers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198808</classIRI>
<classLabel>Subsistence Crop Farmer</classLabel>
<newAxiom>'Subsistence Crop Farmer' SubClassOf 'Farmer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198810</classIRI>
<classLabel>Subsistence Livestock Farmer</classLabel>
<newAxiom>'Subsistence Livestock Farmer' SubClassOf 'Farmer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198812</classIRI>
<classLabel>Telecommunications and Broadcasting Technician</classLabel>
<newAxiom>'Telecommunications and Broadcasting Technician' SubClassOf 'Arts, Design, Entertainment, Sports and Media Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198811</classIRI>
<classLabel>Subsistence Mixed Crop and Livestock Farmer</classLabel>
<newAxiom>'Subsistence Mixed Crop and Livestock Farmer' SubClassOf 'Farmer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198814</classIRI>
<classLabel>Traditional and Complementary Medicine Associate Professional</classLabel>
<newAxiom>'Traditional and Complementary Medicine Associate Professional' SubClassOf 'Personal Care and Service Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198813</classIRI>
<classLabel>Textile, Fur and Leather Products Machine Operator</classLabel>
<newAxiom>'Textile, Fur and Leather Products Machine Operator' SubClassOf 'Equipment Operator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198816</classIRI>
<classLabel>Transport and Storage Laborer</classLabel>
<newAxiom>'Transport and Storage Laborer' SubClassOf 'Transportation and Material Moving Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198815</classIRI>
<classLabel>Traditional and Complementary Medicine Professional</classLabel>
<newAxiom>'Traditional and Complementary Medicine Professional' SubClassOf 'Personal Care and Service Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198818</classIRI>
<classLabel>Vehicle, Window, Laundry and Other Hand Cleaning Worker</classLabel>
<newAxiom>'Vehicle, Window, Laundry and Other Hand Cleaning Worker' SubClassOf 'Personal Care and Service Occupations'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198817</classIRI>
<classLabel>Travel Attendant, Conductor and Guide</classLabel>
<newAxiom>'Travel Attendant, Conductor and Guide' SubClassOf 'Transportation, Tourism, and Lodging Attendants'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198819</classIRI>
<classLabel>Vocational Education Teacher</classLabel>
<newAxiom>'Vocational Education Teacher' SubClassOf 'Teacher'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198821</classIRI>
<classLabel>Wood Treater, Cabinet-maker and Related Trades Worker</classLabel>
<newAxiom>'Wood Treater, Cabinet-maker and Related Trades Worker' SubClassOf 'Trades, Transport, or Construction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198820</classIRI>
<classLabel>Wood Processing and Papermaking Plant Operator</classLabel>
<newAxiom>'Wood Processing and Papermaking Plant Operator' SubClassOf 'Trades, Transport, or Construction'</newAxiom>
<newAxiom>'Wood Processing and Papermaking Plant Operator' SubClassOf 'Plant and System Operators'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198823</classIRI>
<classLabel>Doxorubicin/Streptozocin Regimen</classLabel>
<newAxiom>'Doxorubicin/Streptozocin Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Doxorubicin'</newAxiom>
<newAxiom>'Doxorubicin/Streptozocin Regimen' SubClassOf 'Regimen Used to Treat Malignant Neuroendocrine and Adrenal Neoplasm'</newAxiom>
<newAxiom>'Doxorubicin/Streptozocin Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Streptozocin'</newAxiom>
<newAxiom>'Doxorubicin/Streptozocin Regimen' SubClassOf 'Regimen Used to Treat Thyroid Cancer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198822</classIRI>
<classLabel>Legal, Social and Religious Associate Professional</classLabel>
<newAxiom>'Legal, Social and Religious Associate Professional' SubClassOf 'Administration Professional'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198825</classIRI>
<classLabel>Cisplatin/Nivolumab/Pemetrexed Regimen</classLabel>
<newAxiom>'Cisplatin/Nivolumab/Pemetrexed Regimen' SubClassOf 'Regimen Used to Treat Non-Small Cell Lung Carcinoma'</newAxiom>
<newAxiom>'Cisplatin/Nivolumab/Pemetrexed Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Nivolumab'</newAxiom>
<newAxiom>'Cisplatin/Nivolumab/Pemetrexed Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Pemetrexed Disodium'</newAxiom>
<newAxiom>'Cisplatin/Nivolumab/Pemetrexed Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Cisplatin'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198824</classIRI>
<classLabel>Fluorouracil/Streptozocin Regimen</classLabel>
<newAxiom>'Fluorouracil/Streptozocin Regimen' SubClassOf 'Regimen Used to Treat Malignant Neuroendocrine and Adrenal Neoplasm'</newAxiom>
<newAxiom>'Fluorouracil/Streptozocin Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Streptozocin'</newAxiom>
<newAxiom>'Fluorouracil/Streptozocin Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Fluorouracil'</newAxiom>
<newAxiom>'Fluorouracil/Streptozocin Regimen' SubClassOf 'Regimen Used to Treat Thyroid Cancer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198827</classIRI>
<classLabel>Acute Myeloid Leukemia with STAT3-RARA</classLabel>
<newAxiom>'Acute Myeloid Leukemia with STAT3-RARA' EquivalentTo 'Acute Myeloid Leukemia with a Variant RARA Rearrangement' and ('Disease_Has_Molecular_Abnormality' some 'STAT3-RARA Fusion Protein Expression') and ('Disease_Mapped_To_Gene' some 'STAT3/RARA Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198826</classIRI>
<classLabel>Modified Chang Staging System for Medulloblastoma</classLabel>
<newAxiom>'Modified Chang Staging System for Medulloblastoma' SubClassOf 'Staging System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198829</classIRI>
<classLabel>t(1;17)(q42.3;q21.2)</classLabel>
<newAxiom>'t(1;17)(q42.3;q21.2)' SubClassOf 'RARA Gene Translocation'</newAxiom>
<newAxiom>'t(1;17)(q42.3;q21.2)' SubClassOf 'Chromosome 1 Abnormality'</newAxiom>
<newAxiom>'t(1;17)(q42.3;q21.2)' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'IRF2BP2/RARA Fusion Gene'</newAxiom>
<newAxiom>'t(1;17)(q42.3;q21.2)' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'IRF2BP2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198828</classIRI>
<classLabel>STAT3-RARA Fusion Protein Expression</classLabel>
<newAxiom>'STAT3-RARA Fusion Protein Expression' SubClassOf 'Fusion Protein Expression'</newAxiom>
<newAxiom>'STAT3-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'STAT3/RARA Fusion Gene'</newAxiom>
<newAxiom>'STAT3-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'RARA Gene'</newAxiom>
<newAxiom>'STAT3-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'STAT3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198830</classIRI>
<classLabel>IRF2BP2-RARA Fusion Protein Expression</classLabel>
<newAxiom>'IRF2BP2-RARA Fusion Protein Expression' SubClassOf 'Fusion Protein Expression'</newAxiom>
<newAxiom>'IRF2BP2-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'RARA Gene'</newAxiom>
<newAxiom>'IRF2BP2-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'IRF2BP2/RARA Fusion Gene'</newAxiom>
<newAxiom>'IRF2BP2-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'IRF2BP2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198832</classIRI>
<classLabel>STAT3/RARA Fusion Gene</classLabel>
<newAxiom>'STAT3/RARA Fusion Gene' SubClassOf 'Fusion Gene'</newAxiom>
<newAxiom>'STAT3/RARA Fusion Gene' SubClassOf 'Gene_Involved_In_Pathogenesis_Of_Disease' some 'Acute Myeloid Leukemia with STAT3-RARA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198831</classIRI>
<classLabel>Acute Myeloid Leukemia with t(1;17)(q42.3;q21.2); IRF2BP2-RARA</classLabel>
<newAxiom>'Acute Myeloid Leukemia with t(1;17)(q42.3;q21.2); IRF2BP2-RARA' EquivalentTo 'Acute Myeloid Leukemia with a Variant RARA Rearrangement' and ('Disease_Has_Molecular_Abnormality' some 'IRF2BP2-RARA Fusion Protein Expression') and ('Disease_Has_Cytogenetic_Abnormality' some 't(1;17)(q42.3;q21.2)') and ('Disease_Mapped_To_Gene' some 'IRF2BP2/RARA Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198834</classIRI>
<classLabel>Acute Myeloid Leukemia with TBL1XR1-RARA</classLabel>
<newAxiom>'Acute Myeloid Leukemia with TBL1XR1-RARA' EquivalentTo 'Acute Myeloid Leukemia with a Variant RARA Rearrangement' and ('Disease_Has_Molecular_Abnormality' some 'TBL1XR1-RARA Fusion Protein Expression') and ('Disease_Mapped_To_Gene' some 'TBL1XR1/RARA Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198833</classIRI>
<classLabel>STAT3/RARA Fusion Protein</classLabel>
<newAxiom>'STAT3/RARA Fusion Protein' SubClassOf 'Fusion Protein'</newAxiom>
<newAxiom>'STAT3/RARA Fusion Protein' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'STAT3/RARA Fusion Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198836</classIRI>
<classLabel>TBL1XR1-RARA Fusion Protein Expression</classLabel>
<newAxiom>'TBL1XR1-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'RARA Gene'</newAxiom>
<newAxiom>'TBL1XR1-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'TBL1XR1 Gene'</newAxiom>
<newAxiom>'TBL1XR1-RARA Fusion Protein Expression' SubClassOf 'Fusion Protein Expression'</newAxiom>
<newAxiom>'TBL1XR1-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'TBL1XR1/RARA Fusion Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198835</classIRI>
<classLabel>Experimental Therapeutic Procedure</classLabel>
<newAxiom>'Experimental Therapeutic Procedure' SubClassOf 'Therapeutic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198838</classIRI>
<classLabel>FIP1L1-RARA Fusion Protein Expression</classLabel>
<newAxiom>'FIP1L1-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'FIP1L1 Gene'</newAxiom>
<newAxiom>'FIP1L1-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'RARA Gene'</newAxiom>
<newAxiom>'FIP1L1-RARA Fusion Protein Expression' SubClassOf 'Fusion Protein Expression'</newAxiom>
<newAxiom>'FIP1L1-RARA Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'FIP1L1/RARA Fusion Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198837</classIRI>
<classLabel>Eye Enucleation</classLabel>
<newAxiom>'Eye Enucleation' SubClassOf 'Ophthalmologic Surgical Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198839</classIRI>
<classLabel>Acute Myeloid Leukemia with FIP1L1-RARA</classLabel>
<newAxiom>'Acute Myeloid Leukemia with FIP1L1-RARA' EquivalentTo 'Acute Myeloid Leukemia with a Variant RARA Rearrangement' and ('Disease_Has_Molecular_Abnormality' some 'FIP1L1-RARA Fusion Protein Expression') and ('Disease_Mapped_To_Gene' some 'FIP1L1/RARA Fusion Gene')</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>