<?xml version="1.0"?>
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437
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254
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0
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<classLabel>Number of Events</classLabel>
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<changedClass>
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<classLabel>Percent Blasts in Peripheral Blood at Diagnosis</classLabel>
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<newAxiom>&apos;Percent Blasts in Peripheral Blood at Diagnosis&apos; SubClassOf &apos;Percent Unit&apos;</newAxiom>
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<classLabel>Autologous CMV-pp65-shLAMP-1 mRNA Loaded Dendritic Cell Vaccine</classLabel>
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<newAxiom>&apos;Number of Other Lymph Nodes Positive for Tumor by IHC staining only&apos; SubClassOf &apos;Number of Lymph Nodes Positive for Tumor by IHC Staining Only&apos;</newAxiom>
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<newAxiom>&apos;Number of Pelvic Lymph Nodes Examined&apos; SubClassOf &apos;Number of Lymph Nodes Examined&apos;</newAxiom>
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<newAxiom>&apos;Age at Initial Pathologic Diagnosis&apos; SubClassOf &apos;Age at Diagnosis&apos;</newAxiom>
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<newAxiom>&apos;Number of Days from Date of Initial Pathologic Diagnosis to Date of Tumor Progression after Initial Treatment&apos; SubClassOf &apos;Number of Days from Date of Initial Cancer Diagnosis to Date of New Tumor Event after Initial Treatment&apos;</newAxiom>
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<newAxiom>&apos;Number of Days from Date of Initial Pathologic Diagnosis to Date of Tumor Reoccurrence After Initial Treatment&apos; SubClassOf &apos;Number of Days from Date of Initial Cancer Diagnosis to Date of New Tumor Event after Initial Treatment&apos;</newAxiom>
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<newAxiom>&apos;Number of Other Lymph Nodes Examined&apos; SubClassOf &apos;Number of Lymph Nodes Examined&apos;</newAxiom>
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<classLabel>Months Since Completion of Primary Therapy</classLabel>
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<classLabel>Primary Site Unknown</classLabel>
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<newAxiom>&apos;Primary Site Unknown&apos; SubClassOf &apos;Clinical Course of Disease&apos;</newAxiom>
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<classLabel>Lucatumumab</classLabel>
<deletedAxiom>&apos;Lucatumumab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Lucatumumab&apos; SubClassOf &apos;Anti-CD40 Monoclonal Antibody&apos;</newAxiom>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34068</classIRI>
<classLabel>Protein PML</classLabel>
<deletedAxiom>&apos;Protein PML&apos; EquivalentTo &apos;Transcription Factor&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Ubiquitin-mediated Proteolysis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;PML Transcription Regulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Endocytosis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Acute Myeloid Leukemia Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;p53 Effector Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;mTOR Signaling Pathway PID&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;TGF-Beta Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Ring Finger Domain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;TRIM Motif&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Binding&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Negative Regulation of Cell Cycle&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Regulation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Positive Regulation of Apoptosis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Tumor Suppression&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;PML Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Protein PML&apos; EquivalentTo &apos;Transcription Factor&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Ubiquitin-mediated Proteolysis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;PML Transcription Regulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Endocytosis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Acute Myeloid Leukemia Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;p53 Effector Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;mTOR Signaling Pathway PID&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;TGF-Beta Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Ring Finger Domain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;TRIM Motif&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;TRIM Family&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Binding&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Negative Regulation of Cell Cycle&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Regulation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Positive Regulation of Apoptosis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Tumor Suppression&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;PML Gene&apos;)</newAxiom>
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<classLabel>Cloth</classLabel>
<deletedAxiom>&apos;Cloth&apos; SubClassOf &apos;Material&apos;</deletedAxiom>
<newAxiom>&apos;Cloth&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
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<classLabel>CD86 Positive</classLabel>
<newAxiom>&apos;CD86 Positive&apos; SubClassOf &apos;Receptor Status&apos;</newAxiom>
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<classLabel>Anti-BCMA/PBD ADC MEDI2228</classLabel>
<deletedAxiom>&apos;Anti-BCMA/PBD ADC MEDI2228&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-BCMA/PBD ADC MEDI2228&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181108</newAxiom>
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<classLabel>EGFR NP_005219.2:p.S768I</classLabel>
<deletedAxiom>&apos;EGFR NP_005219.2:p.S768I&apos; SubClassOf &apos;EGFR Protein Variant&apos;</deletedAxiom>
<newAxiom>&apos;EGFR NP_005219.2:p.S768I&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180970</newAxiom>
</changedClass>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125209</classIRI>
<classLabel>EGFR NM_005228.3:c.2303GT</classLabel>
<deletedAxiom>&apos;EGFR NM_005228.3:c.2303GT&apos; SubClassOf &apos;EGFR Exon 20 Mutation&apos;</deletedAxiom>
<deletedAxiom>&apos;EGFR NM_005228.3:c.2303GT&apos; SubClassOf &apos;EGFR Activating Mutation&apos;</deletedAxiom>
<newAxiom>&apos;EGFR NM_005228.3:c.2303GT&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180953</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C164668</classIRI>
<classLabel>Anti-alpha BCMA/Anti-alpha CD3 T-cell Engaging Bispecific Antibody TNB-383B</classLabel>
<deletedAxiom>&apos;Anti-alpha BCMA/Anti-alpha CD3 T-cell Engaging Bispecific Antibody TNB-383B&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-alpha BCMA/Anti-alpha CD3 T-cell Engaging Bispecific Antibody TNB-383B&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181114</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C164655</classIRI>
<classLabel>Unplanned Treatment Indicator</classLabel>
<deletedAxiom>&apos;Unplanned Treatment Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Unplanned Treatment Indicator&apos; SubClassOf &apos;Therapeutic Indicator&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C164208</classIRI>
<classLabel>BRD3 Gene Translocation</classLabel>
<deletedAxiom>&apos;BRD3 Gene Translocation&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;BRD3 Gene Translocation&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C93581</classIRI>
<classLabel>Involved Surgical Margin Indicator</classLabel>
<deletedAxiom>&apos;Involved Surgical Margin Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Involved Surgical Margin Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54056</classIRI>
<classLabel>Preexisting Condition</classLabel>
<deletedAxiom>&apos;Preexisting Condition&apos; SubClassOf &apos;Medical Condition&apos;</deletedAxiom>
<newAxiom>&apos;Preexisting Condition&apos; SubClassOf &apos;Clinical Course of Disease&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C164023</classIRI>
<classLabel>Initial Genomic Sequencing Date</classLabel>
<deletedAxiom>&apos;Initial Genomic Sequencing Date&apos; SubClassOf &apos;Date of Therapeutic Procedure&apos;</deletedAxiom>
<newAxiom>&apos;Initial Genomic Sequencing Date&apos; SubClassOf &apos;Index Date&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C139062</classIRI>
<classLabel>Heart Chamber Enlargement Indicator</classLabel>
<deletedAxiom>&apos;Heart Chamber Enlargement Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Heart Chamber Enlargement Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C139063</classIRI>
<classLabel>Heart Chamber Hypertrophy Indicator</classLabel>
<deletedAxiom>&apos;Heart Chamber Hypertrophy Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Heart Chamber Hypertrophy Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178636</classIRI>
<classLabel>W_pro1 Cancer Vaccine</classLabel>
<deletedAxiom>&apos;W_pro1 Cancer Vaccine&apos; SubClassOf &apos;mRNA Vaccine&apos;</deletedAxiom>
<deletedAxiom>&apos;W_pro1 Cancer Vaccine&apos; SubClassOf &apos;Antineoplastic Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;W_pro1 Cancer Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C139038</classIRI>
<classLabel>Aneurysm Indicator</classLabel>
<deletedAxiom>&apos;Aneurysm Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Aneurysm Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C139039</classIRI>
<classLabel>Dissection Indicator</classLabel>
<deletedAxiom>&apos;Dissection Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Dissection Indicator&apos; SubClassOf &apos;Symptom Indicator&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C139033</classIRI>
<classLabel>Aortic Coarctation Indicator</classLabel>
<deletedAxiom>&apos;Aortic Coarctation Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Aortic Coarctation Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C139055</classIRI>
<classLabel>Cardiac Valvular Regurgitation Indicator</classLabel>
<deletedAxiom>&apos;Cardiac Valvular Regurgitation Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Cardiac Valvular Regurgitation Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C139057</classIRI>
<classLabel>Eccentric Regurgitant Jet Indicator</classLabel>
<deletedAxiom>&apos;Eccentric Regurgitant Jet Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Eccentric Regurgitant Jet Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C139046</classIRI>
<classLabel>Pericardial Effusion Indicator</classLabel>
<deletedAxiom>&apos;Pericardial Effusion Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Pericardial Effusion Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20819</classIRI>
<classLabel>Nucleoporin Gene</classLabel>
<newAxiom>&apos;Nucleoporin Gene&apos; SubClassOf &apos;Structural Protein Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178309</classIRI>
<classLabel>Autologous mRNA-encoding NSCLC Neoantigens Dendritic Cell Vaccine</classLabel>
<newAxiom>&apos;Autologous mRNA-encoding NSCLC Neoantigens Dendritic Cell Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178431</classIRI>
<classLabel>NR4A3 Gene Rearrangement</classLabel>
<deletedAxiom>&apos;NR4A3 Gene Rearrangement&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;NR4A3 Gene Rearrangement&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178432</classIRI>
<classLabel>Autologous Total Tumor mRNA and CMV-pp65-flLAMP mRNA Loaded Liposome Vaccine</classLabel>
<deletedAxiom>&apos;Autologous Total Tumor mRNA and CMV-pp65-flLAMP mRNA Loaded Liposome Vaccine&apos; SubClassOf &apos;mRNA Vaccine&apos;</deletedAxiom>
<deletedAxiom>&apos;Autologous Total Tumor mRNA and CMV-pp65-flLAMP mRNA Loaded Liposome Vaccine&apos; SubClassOf &apos;Antineoplastic Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Total Tumor mRNA and CMV-pp65-flLAMP mRNA Loaded Liposome Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178410</classIRI>
<classLabel>Anti-PSMA Antibody-drug Conjugate ARX517</classLabel>
<newAxiom>&apos;Anti-PSMA Antibody-drug Conjugate ARX517&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178403</classIRI>
<classLabel>HPV16 E6/7 mRNA Vaccine BNT113</classLabel>
<deletedAxiom>&apos;HPV16 E6/7 mRNA Vaccine BNT113&apos; SubClassOf &apos;Antineoplastic Vaccine&apos;</deletedAxiom>
<deletedAxiom>&apos;HPV16 E6/7 mRNA Vaccine BNT113&apos; SubClassOf &apos;mRNA Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;HPV16 E6/7 mRNA Vaccine BNT113&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54635</classIRI>
<classLabel>Primary Site Unspecified</classLabel>
<deletedAxiom>&apos;Primary Site Unspecified&apos; SubClassOf &apos;Primary Site of Disease&apos;</deletedAxiom>
<newAxiom>&apos;Primary Site Unspecified&apos; SubClassOf &apos;Clinical Course of Disease&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54732</classIRI>
<classLabel>Preoperative</classLabel>
<deletedAxiom>&apos;Preoperative&apos; SubClassOf &apos;Temporal Qualifier&apos;</deletedAxiom>
<newAxiom>&apos;Preoperative&apos; SubClassOf &apos;Pre-Procedure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40243</classIRI>
<classLabel>Vaginal Keratinizing Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Vaginal Keratinizing Squamous Cell Carcinoma&apos; EquivalentTo &apos;Keratinizing Squamous Cell Carcinoma&apos; and &apos;Vaginal Squamous Cell Carcinoma, Not Otherwise Specified&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Dysuria&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Postcoital Bleeding&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pelvic Pain&apos;)</deletedAxiom>
<newAxiom>&apos;Vaginal Keratinizing Squamous Cell Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180915 and &apos;Keratinizing Squamous Cell Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Dysuria&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Postcoital Bleeding&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pelvic Pain&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40248</classIRI>
<classLabel>Vaginal Warty Carcinoma</classLabel>
<deletedAxiom>&apos;Vaginal Warty Carcinoma&apos; EquivalentTo &apos;Warty Carcinoma&apos; and &apos;Human Papillomavirus-Related Squamous Cell Carcinoma&apos; and &apos;Vaginal Squamous Cell Carcinoma, Not Otherwise Specified&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Exophytic Papillary Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Postcoital Bleeding&apos;)</deletedAxiom>
<newAxiom>&apos;Vaginal Warty Carcinoma&apos; EquivalentTo &apos;Warty Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180917 and (&apos;Disease_Has_Finding&apos; some &apos;Exophytic Papillary Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Postcoital Bleeding&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40244</classIRI>
<classLabel>Vaginal Non-Keratinizing Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Vaginal Non-Keratinizing Squamous Cell Carcinoma&apos; EquivalentTo &apos;Vaginal Squamous Cell Carcinoma, Not Otherwise Specified&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Non-Keratinizing Malignant Squamous Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Keratinizing Malignant Squamous Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Dysuria&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Postcoital Bleeding&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pelvic Pain&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Keratin Pearls Formation&apos;)</deletedAxiom>
<newAxiom>&apos;Vaginal Non-Keratinizing Squamous Cell Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180915 and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Non-Keratinizing Malignant Squamous Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Keratinizing Malignant Squamous Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Dysuria&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Postcoital Bleeding&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pelvic Pain&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Keratin Pearls Formation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40245</classIRI>
<classLabel>Vaginal Basaloid Carcinoma</classLabel>
<deletedAxiom>&apos;Vaginal Basaloid Carcinoma&apos; EquivalentTo &apos;Basaloid Squamous Cell Carcinoma&apos; and &apos;Vaginal Squamous Cell Carcinoma, Not Otherwise Specified&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Dysuria&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Postcoital Bleeding&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pelvic Pain&apos;)</deletedAxiom>
<newAxiom>&apos;Vaginal Basaloid Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180915 and &apos;Basaloid Squamous Cell Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Dysuria&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Postcoital Bleeding&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pelvic Pain&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40257</classIRI>
<classLabel>Vaginal Tubular Adenoma</classLabel>
<deletedAxiom>&apos;Vaginal Tubular Adenoma&apos; EquivalentTo &apos;Vaginal Adenoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Tubular Pattern&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Villous Pattern&apos;)</deletedAxiom>
<newAxiom>&apos;Vaginal Tubular Adenoma&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C143051</classIRI>
<classLabel>Crooked Neck-Like Protein 1</classLabel>
<deletedAxiom>&apos;Crooked Neck-Like Protein 1&apos; SubClassOf &apos;RNA Binding Protein&apos;</deletedAxiom>
<deletedAxiom>&apos;Crooked Neck-Like Protein 1&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;RNA Splicing&apos;</deletedAxiom>
<deletedAxiom>&apos;Crooked Neck-Like Protein 1&apos; SubClassOf &apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;Crooked Neck-Like Protein 1&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CRNKL1 Gene&apos;</deletedAxiom>
<deletedAxiom>&apos;Crooked Neck-Like Protein 1&apos; SubClassOf &apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Proline-Rich Domain&apos;</deletedAxiom>
<deletedAxiom>&apos;Crooked Neck-Like Protein 1&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;RNA Binding&apos;</deletedAxiom>
<newAxiom>&apos;Crooked Neck-Like Protein 1&apos; EquivalentTo &apos;RNA Binding Protein&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Proline-Rich Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;RNA Splicing&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;RNA Binding&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CRNKL1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88260</classIRI>
<classLabel>WT1 mRNA-Electroporated Autologous Dendritic Cell Vaccine</classLabel>
<newAxiom>&apos;WT1 mRNA-Electroporated Autologous Dendritic Cell Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157434</classIRI>
<classLabel>Month/Year of Diagnosis</classLabel>
<deletedAxiom>&apos;Month/Year of Diagnosis&apos; SubClassOf &apos;Date&apos;</deletedAxiom>
<newAxiom>&apos;Month/Year of Diagnosis&apos; SubClassOf &apos;Month-Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157572</classIRI>
<classLabel>JAK2 Gene Rearrangement</classLabel>
<deletedAxiom>&apos;JAK2 Gene Rearrangement&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;JAK2 Gene Rearrangement&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74000</classIRI>
<classLabel>AML mRNA Positive Lysate Loaded Autologous Dendritic Cell Vaccine</classLabel>
<newAxiom>&apos;AML mRNA Positive Lysate Loaded Autologous Dendritic Cell Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15889</classIRI>
<classLabel>Traditional Indigenous System</classLabel>
<deletedAxiom>&apos;Traditional Indigenous System&apos; SubClassOf &apos;Alternative Medical System&apos;</deletedAxiom>
<newAxiom>&apos;Traditional Indigenous System&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180905</newAxiom>
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<newAxiom>&apos;Gonadotropin&apos; SubClassOf &apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Glycoprotein&apos;</newAxiom>
<newAxiom>&apos;Gonadotropin&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;G Protein-Coupled Receptor Signaling&apos;</newAxiom>
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<classLabel>Beta-Cell Function Measurement</classLabel>
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<changedClass>
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<classLabel>Anti-Double Stranded DNA Measurement</classLabel>
<deletedAxiom>&apos;Anti-Double Stranded DNA Measurement&apos; SubClassOf &apos;Immunology Test&apos;</deletedAxiom>
<newAxiom>&apos;Anti-Double Stranded DNA Measurement&apos; SubClassOf &apos;Anti-DNA Antibody Measurement&apos;</newAxiom>
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<changedClass>
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<classLabel>EGFR NM_005228.5:c.2305GT</classLabel>
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<deletedAxiom>&apos;EGFR NM_005228.5:c.2305GT&apos; SubClassOf &apos;EGFR Exon 20 Mutation&apos;</deletedAxiom>
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<changedClass>
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<classLabel>EGFR NM_005228.2:c.2499GT</classLabel>
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<deletedAxiom>&apos;EGFR NM_005228.2:c.2499GT&apos; SubClassOf &apos;EGFR Exon 21 Mutation&apos;</deletedAxiom>
<newAxiom>&apos;EGFR NM_005228.2:c.2499GT&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180963</newAxiom>
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<changedClass>
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<classLabel>Nucleoporin</classLabel>
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<newAxiom>&apos;Nucleoporin&apos; SubClassOf &apos;Transport Protein&apos;</newAxiom>
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<changedClass>
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<classLabel>Glycocholic Acid Measurement</classLabel>
<deletedAxiom>&apos;Glycocholic Acid Measurement&apos; SubClassOf &apos;Protein or Enzyme Type Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Glycocholic Acid Measurement&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Anti-CTLA4 MoAb RNA-transfected Autologous Dendritic Cell Vaccine</classLabel>
<newAxiom>&apos;Anti-CTLA4 MoAb RNA-transfected Autologous Dendritic Cell Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
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<changedClass>
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<classLabel>Anti-CTLA4 MoAb RNA/GITRL RNA-transfected Autologous Dendritic Cell Vaccine</classLabel>
<newAxiom>&apos;Anti-CTLA4 MoAb RNA/GITRL RNA-transfected Autologous Dendritic Cell Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
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<classLabel>Vascular Endothelial Growth Factor C Measurement</classLabel>
<deletedAxiom>&apos;Vascular Endothelial Growth Factor C Measurement&apos; SubClassOf &apos;Protein or Enzyme Type Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Vascular Endothelial Growth Factor C Measurement&apos; SubClassOf &apos;Vascular Endothelial Growth Factor Measurement&apos;</newAxiom>
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<changedClass>
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<classLabel>Millisecond per Millimeter Mercury</classLabel>
<deletedAxiom>&apos;Millisecond per Millimeter Mercury&apos; SubClassOf &apos;Unit of Measure&apos;</deletedAxiom>
<newAxiom>&apos;Millisecond per Millimeter Mercury&apos; SubClassOf &apos;Unit of Dose Calculation&apos;</newAxiom>
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<changedClass>
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<classLabel>EGFR Exon 20 Tyrosine Kinase Inhibitor Resistant Mutation</classLabel>
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<newAxiom>&apos;EGFR Exon 20 Tyrosine Kinase Inhibitor Resistant Mutation&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180953</newAxiom>
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<changedClass>
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<classLabel>Ovarian Surface Involvement Indicator</classLabel>
<deletedAxiom>&apos;Ovarian Surface Involvement Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Ovarian Surface Involvement Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
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<changedClass>
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<classLabel>Rhabdoid Indicator</classLabel>
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<newAxiom>&apos;Rhabdoid Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
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<changedClass>
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<classLabel>Risk Factor Treatment Indicator</classLabel>
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<newAxiom>&apos;Risk Factor Treatment Indicator&apos; SubClassOf &apos;Therapeutic Indicator&apos;</newAxiom>
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<changedClass>
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<classLabel>MTAP Gene Deletion</classLabel>
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<newAxiom>&apos;MTAP Gene Deletion&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
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<classLabel>EGFR NM_005228.5:c.2224GA</classLabel>
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<deletedAxiom>&apos;EGFR NM_005228.5:c.2224GA&apos; SubClassOf &apos;EGFR Activating Mutation&apos;</deletedAxiom>
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<deletedAxiom>&apos;EGFR NM_005228.5:c.2491CT&apos; SubClassOf &apos;EGFR Activating Mutation&apos;</deletedAxiom>
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<classLabel>EGFR NM_005228.5:c.2320GA</classLabel>
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<deletedAxiom>&apos;EGFR NM_005228.5:c.2320GA&apos; SubClassOf &apos;EGFR Exon 20 Mutation&apos;</deletedAxiom>
<newAxiom>&apos;EGFR NM_005228.5:c.2320GA&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180953</newAxiom>
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<classLabel>EGFR NM_005228.5:c.2591CT</classLabel>
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<deletedAxiom>&apos;EGFR NM_005228.5:c.2591CT&apos; SubClassOf &apos;EGFR Exon 21 Mutation&apos;</deletedAxiom>
<newAxiom>&apos;EGFR NM_005228.5:c.2591CT&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180963</newAxiom>
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<classLabel>EGFR NM_005228.5:c.2305GC</classLabel>
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<deletedAxiom>&apos;EGFR NM_005228.5:c.2305GC&apos; SubClassOf &apos;EGFR Exon 20 Mutation&apos;</deletedAxiom>
<newAxiom>&apos;EGFR NM_005228.5:c.2305GC&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180953</newAxiom>
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<classLabel>Columnar Mucosa Indicator</classLabel>
<deletedAxiom>&apos;Columnar Mucosa Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Columnar Mucosa Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177587</classIRI>
<classLabel>Bone Marrow Malignant Cell Indicator</classLabel>
<deletedAxiom>&apos;Bone Marrow Malignant Cell Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Bone Marrow Malignant Cell Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177591</classIRI>
<classLabel>Esophageal Columnar Metaplasia Indicator</classLabel>
<deletedAxiom>&apos;Esophageal Columnar Metaplasia Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Esophageal Columnar Metaplasia Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
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<changedClass>
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<classLabel>Gastroesophageal Junction Involvement Indicator</classLabel>
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<newAxiom>&apos;Gastroesophageal Junction Involvement Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
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<changedClass>
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<classLabel>Esophageal Columnar Mucosa Goblet Cell Indicator</classLabel>
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<newAxiom>&apos;Esophageal Columnar Mucosa Goblet Cell Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177594</classIRI>
<classLabel>Hysterectomy Margins Involved Indicator</classLabel>
<deletedAxiom>&apos;Hysterectomy Margins Involved Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Hysterectomy Margins Involved Indicator&apos; SubClassOf &apos;Involved Surgical Margin Indicator&apos;</newAxiom>
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<changedClass>
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<classLabel>Metaplasia Indicator</classLabel>
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<newAxiom>&apos;Metaplasia Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177596</classIRI>
<classLabel>Necrosis Indicator</classLabel>
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<newAxiom>&apos;Necrosis Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177598</classIRI>
<classLabel>Non-nodal Tumor Deposits Indicator</classLabel>
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<newAxiom>&apos;Non-nodal Tumor Deposits Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177307</classIRI>
<classLabel>del(9p21)</classLabel>
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<newAxiom>&apos;del(9p21)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
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<changedClass>
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<classLabel>Fasting Blood Sugar Measurement</classLabel>
<deletedAxiom>&apos;Fasting Blood Sugar Measurement&apos; SubClassOf &apos;Blood Chemistry Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Fasting Blood Sugar Measurement&apos; SubClassOf &apos;Blood Glucose Measurement&apos;</newAxiom>
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<changedClass>
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<classLabel>Number of Stem Cell Transplant Cycles</classLabel>
<deletedAxiom>&apos;Number of Stem Cell Transplant Cycles&apos; SubClassOf &apos;Number&apos;</deletedAxiom>
<newAxiom>&apos;Number of Stem Cell Transplant Cycles&apos; SubClassOf &apos;Number of Procedures Performed&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104399</classIRI>
<classLabel>Follitropin Subunit Beta</classLabel>
<deletedAxiom>&apos;Follitropin Subunit Beta&apos; EquivalentTo &apos;Peptide Hormone&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Spermatogenesis Regulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Neuroactive Ligand-Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Gonadotropin-Releasing Hormone Signaling Pathway&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Gametogenesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Pregnancy&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;FSHB Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Follitropin Subunit Beta&apos; EquivalentTo &apos;Peptide Hormone&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Spermatogenesis Regulation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Neuroactive Ligand-Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Gonadotropin-Releasing Hormone Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181076) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Gametogenesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;G Protein-Coupled Receptor Signaling&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;FSHB Gene&apos;)</newAxiom>
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<changedClass>
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<classLabel>KIF2C Gene</classLabel>
<newAxiom>&apos;KIF2C Gene&apos; SubClassOf &apos;Cell Cycle Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104358</classIRI>
<classLabel>Kinesin-Like Protein KIF2C</classLabel>
<deletedAxiom>&apos;Kinesin-Like Protein KIF2C&apos; EquivalentTo &apos;Transport Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Aurora B Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Centromere&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Microtubule&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Microtubule Associated Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Microtubule Depolymerization Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Chromosome Segregation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Prometaphase&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;KIF2C Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Kinesin-Like Protein KIF2C&apos; EquivalentTo &apos;Transport Protein&apos; and &apos;Cell Cycle Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Aurora B Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Centromere&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Microtubule&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Microtubule Associated Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Microtubule Depolymerization Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Chromosome Segregation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Prometaphase&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;KIF2C Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177185</classIRI>
<classLabel>Transcriptional Intermediary Factor 1-Beta</classLabel>
<deletedAxiom>&apos;Transcriptional Intermediary Factor 1-Beta&apos; EquivalentTo &apos;Acyltransferase&apos; and &apos;Transcription Regulatory Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;p53 Pathway for Transcriptional Regulation&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;E2F Transcription Factor Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Bromodomain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Ring Finger Domain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Coiled-Coil Domain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;TRIM Motif&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;PHD Finger&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Transcription Repressor/Corepressor&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Post-Translational Modification&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Chromatin Remodeling&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Antiviral Response&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TRIM28 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Transcriptional Intermediary Factor 1-Beta&apos; EquivalentTo &apos;Acyltransferase&apos; and &apos;Transcription Regulatory Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;p53 Pathway for Transcriptional Regulation&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;E2F Transcription Factor Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Nucleus&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Bromodomain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Ring Finger Domain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Coiled-Coil Domain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;TRIM Motif&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;PHD Finger&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Transcription Repressor/Corepressor&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;TRIM Family&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Post-Translational Modification&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Chromatin Remodeling&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Antiviral Response&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TRIM28 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104161</classIRI>
<classLabel>KIF23 Gene</classLabel>
<newAxiom>&apos;KIF23 Gene&apos; SubClassOf &apos;Cell Cycle Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104163</classIRI>
<classLabel>Kinesin-Like Protein KIF23</classLabel>
<deletedAxiom>&apos;Kinesin-Like Protein KIF23&apos; EquivalentTo &apos;Transport Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Aurora B Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Microtubule&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Contractile System&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Microtubule Associated Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cytokinesis&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;KIF23 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Kinesin-Like Protein KIF23&apos; EquivalentTo &apos;Transport Protein&apos; and &apos;Cell Cycle Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Aurora B Signaling Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Microtubule&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Contractile System&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Microtubule Associated Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cytokinesis&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;KIF23 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118760</classIRI>
<classLabel>Abnormal Vision</classLabel>
<deletedAxiom>&apos;Abnormal Vision&apos; SubClassOf &apos;Sign or Symptom&apos;</deletedAxiom>
<newAxiom>&apos;Abnormal Vision&apos; SubClassOf &apos;Sensory Manifestations&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41376</classIRI>
<classLabel>Plasma Glucose Measurement</classLabel>
<deletedAxiom>&apos;Plasma Glucose Measurement&apos; SubClassOf &apos;Blood Chemistry Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Plasma Glucose Measurement&apos; SubClassOf &apos;Glucose Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132317</classIRI>
<classLabel>CDISC SDTM Genetic Region of Interest Type Terminology</classLabel>
<deletedAxiom>&apos;CDISC SDTM Genetic Region of Interest Type Terminology&apos; SubClassOf &apos;CDISC SDTM Terminology&apos;</deletedAxiom>
<newAxiom>&apos;CDISC SDTM Genetic Region of Interest Type Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132389</classIRI>
<classLabel>Vascular Endothelial Growth Factor A Measurement</classLabel>
<deletedAxiom>&apos;Vascular Endothelial Growth Factor A Measurement&apos; SubClassOf &apos;Protein or Enzyme Type Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Vascular Endothelial Growth Factor A Measurement&apos; SubClassOf &apos;Vascular Endothelial Growth Factor Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132354</classIRI>
<classLabel>Associated Persons Demographics Submission Domain</classLabel>
<deletedAxiom>&apos;Associated Persons Demographics Submission Domain&apos; SubClassOf &apos;Submission Domain&apos;</deletedAxiom>
<newAxiom>&apos;Associated Persons Demographics Submission Domain&apos; SubClassOf &apos;Associated Persons Domain&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132370</classIRI>
<classLabel>1,3-Beta-D-Glucan Measurement</classLabel>
<deletedAxiom>&apos;1,3-Beta-D-Glucan Measurement&apos; SubClassOf &apos;Immunology Test&apos;</deletedAxiom>
<newAxiom>&apos;1,3-Beta-D-Glucan Measurement&apos; SubClassOf &apos;Chemistry Test&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41615</classIRI>
<classLabel>CDKN2A Gene Deletion</classLabel>
<deletedAxiom>&apos;CDKN2A Gene Deletion&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;CDKN2A Gene Deletion&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107477</classIRI>
<classLabel>ELAV-Like Protein 1</classLabel>
<deletedAxiom>&apos;ELAV-Like Protein 1&apos; SubClassOf &apos;RNA Binding Protein&apos;</deletedAxiom>
<deletedAxiom>&apos;ELAV-Like Protein 1&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Translational Regulation&apos;</deletedAxiom>
<deletedAxiom>&apos;ELAV-Like Protein 1&apos; SubClassOf &apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;RNA Recognition Motif&apos;</deletedAxiom>
<deletedAxiom>&apos;ELAV-Like Protein 1&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;RNA Binding&apos;</deletedAxiom>
<deletedAxiom>&apos;ELAV-Like Protein 1&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ELAVL1 Gene&apos;</deletedAxiom>
<newAxiom>&apos;ELAV-Like Protein 1&apos; EquivalentTo &apos;RNA Binding Protein&apos; and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;RNA Recognition Motif&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;RNA Binding&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Translational Regulation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;ELAVL1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132465</classIRI>
<classLabel>Two or More Persisting New Bone Lesions Indicator</classLabel>
<deletedAxiom>&apos;Two or More Persisting New Bone Lesions Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Two or More Persisting New Bone Lesions Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132490</classIRI>
<classLabel>Two or More New Bone Lesions Indicator</classLabel>
<deletedAxiom>&apos;Two or More New Bone Lesions Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Two or More New Bone Lesions Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107154</classIRI>
<classLabel>EGFR NP_005219.2:p.G719X</classLabel>
<deletedAxiom>&apos;EGFR NP_005219.2:p.G719X&apos; SubClassOf &apos;Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant&apos; some &apos;EGFR Exon 18 Mutation&apos;</deletedAxiom>
<deletedAxiom>&apos;EGFR NP_005219.2:p.G719X&apos; SubClassOf &apos;Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant&apos; some &apos;EGFR Activating Mutation&apos;</deletedAxiom>
<newAxiom>&apos;EGFR NP_005219.2:p.G719X&apos; SubClassOf &apos;Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180951</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C146860</classIRI>
<classLabel>Anti-CD3/Anti-BCMA Bispecific Monoclonal Antibody PF-06863135</classLabel>
<deletedAxiom>&apos;Anti-CD3/Anti-BCMA Bispecific Monoclonal Antibody PF-06863135&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-CD3/Anti-BCMA Bispecific Monoclonal Antibody PF-06863135&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD3/Anti-BCMA Bispecific Monoclonal Antibody PF-06863135&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181114</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C146813</classIRI>
<classLabel>mRNA-based Personalized Cancer Vaccine mRNA-4157</classLabel>
<deletedAxiom>&apos;mRNA-based Personalized Cancer Vaccine mRNA-4157&apos; SubClassOf &apos;Antineoplastic Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;mRNA-based Personalized Cancer Vaccine mRNA-4157&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171521</classIRI>
<classLabel>Pneumonia Indicator</classLabel>
<deletedAxiom>&apos;Pneumonia Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Pneumonia Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C146671</classIRI>
<classLabel>FLT3 Positive</classLabel>
<newAxiom>&apos;FLT3 Positive&apos; SubClassOf &apos;Receptor Status&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171631</classIRI>
<classLabel>BCMA/CD3e Tri-specific T-cell Activating Construct HPN217</classLabel>
<newAxiom>&apos;BCMA/CD3e Tri-specific T-cell Activating Construct HPN217&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181111</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C146648</classIRI>
<classLabel>BRCA1 Polymorphism Positive</classLabel>
<newAxiom>&apos;BRCA1 Polymorphism Positive&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180928</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61077</classIRI>
<classLabel>Autologous Dendritic Cell-Autologous Tumor mRNA-Human CD40L Vaccine</classLabel>
<newAxiom>&apos;Autologous Dendritic Cell-Autologous Tumor mRNA-Human CD40L Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171048</classIRI>
<classLabel>KIR3DL2 Positive</classLabel>
<newAxiom>&apos;KIR3DL2 Positive&apos; SubClassOf &apos;Receptor Status&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36349</classIRI>
<classLabel>t(7;9)(q34;q34.3)</classLabel>
<deletedAxiom>&apos;t(7;9)(q34;q34.3)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;t(7;9)(q34;q34.3)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36366</classIRI>
<classLabel>t(9;11)(q21;q23)</classLabel>
<deletedAxiom>&apos;t(9;11)(q21;q23)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;t(9;11)(q21;q23)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36370</classIRI>
<classLabel>t(9;11)(p21.3;q23.3)</classLabel>
<deletedAxiom>&apos;t(9;11)(p21.3;q23.3)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;t(9;11)(p21.3;q23.3)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36440</classIRI>
<classLabel>Gain of Chromosome 9p</classLabel>
<deletedAxiom>&apos;Gain of Chromosome 9p&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;Gain of Chromosome 9p&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36463</classIRI>
<classLabel>Gain of Chromosome 9</classLabel>
<deletedAxiom>&apos;Gain of Chromosome 9&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;Gain of Chromosome 9&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36483</classIRI>
<classLabel>Gain of Chromosome 9q</classLabel>
<deletedAxiom>&apos;Gain of Chromosome 9q&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;Gain of Chromosome 9q&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36401</classIRI>
<classLabel>t(8;9)(p11;q32-34)</classLabel>
<deletedAxiom>&apos;t(8;9)(p11;q32-34)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;t(8;9)(p11;q32-34)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36532</classIRI>
<classLabel>t(6;9)(p23;q34.1)</classLabel>
<deletedAxiom>&apos;t(6;9)(p23;q34.1)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;t(6;9)(p23;q34.1)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36552</classIRI>
<classLabel>Gain of Chromosome 1p31</classLabel>
<deletedAxiom>&apos;Gain of Chromosome 1p31&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 1&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36584</classIRI>
<classLabel>Loss of Chromosome 9</classLabel>
<deletedAxiom>&apos;Loss of Chromosome 9&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;Loss of Chromosome 9&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36574</classIRI>
<classLabel>del(9p22-pter)</classLabel>
<deletedAxiom>&apos;del(9p22-pter)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;del(9p22-pter)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36592</classIRI>
<classLabel>Gain of Chromosome 9q34</classLabel>
<deletedAxiom>&apos;Gain of Chromosome 9q34&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;Gain of Chromosome 9q34&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36508</classIRI>
<classLabel>Monosomy 9</classLabel>
<deletedAxiom>&apos;Monosomy 9&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;Monosomy 9&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36604</classIRI>
<classLabel>del(9p21p22)</classLabel>
<deletedAxiom>&apos;del(9p21p22)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;del(9p21p22)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36603</classIRI>
<classLabel>t(7;9)(q34;q32)</classLabel>
<deletedAxiom>&apos;t(7;9)(q34;q32)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;t(7;9)(q34;q32)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36648</classIRI>
<classLabel>der(1;16)(q10;p10)</classLabel>
<deletedAxiom>&apos;der(1;16)(q10;p10)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 1&apos;</deletedAxiom>
<newAxiom>&apos;der(1;16)(q10;p10)&apos; SubClassOf &apos;Chromosome 1 Abnormality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36636</classIRI>
<classLabel>Loss of Chromosome 9p</classLabel>
<deletedAxiom>&apos;Loss of Chromosome 9p&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;Loss of Chromosome 9p&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C147028</classIRI>
<classLabel>Pavurutamab</classLabel>
<deletedAxiom>&apos;Pavurutamab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Pavurutamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181113</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C147018</classIRI>
<classLabel>EGFR NP_005219.2:p.L718V</classLabel>
<deletedAxiom>&apos;EGFR NP_005219.2:p.L718V&apos; SubClassOf &apos;Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant&apos; some &apos;EGFR Exon 18 Mutation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C147017</classIRI>
<classLabel>EGFR NP_005219.2:p.L792Y</classLabel>
<deletedAxiom>&apos;EGFR NP_005219.2:p.L792Y&apos; SubClassOf &apos;Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant&apos; some &apos;EGFR Exon 20 Mutation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C147054</classIRI>
<classLabel>ROS1 Gene Rearrangement Negative</classLabel>
<deletedAxiom>&apos;ROS1 Gene Rearrangement Negative&apos; SubClassOf &apos;Genetic Finding&apos;</deletedAxiom>
<newAxiom>&apos;ROS1 Gene Rearrangement Negative&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180950</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C152979</classIRI>
<classLabel>Immunomodulator LAM-003</classLabel>
<deletedAxiom>&apos;Immunomodulator LAM-003&apos; SubClassOf &apos;Immunotherapeutic Agent&apos;</deletedAxiom>
<newAxiom>&apos;Immunomodulator LAM-003&apos; SubClassOf &apos;HSP90 Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95283</classIRI>
<classLabel>Transcription Intermediary Factor 1-Alpha</classLabel>
<deletedAxiom>&apos;Transcription Intermediary Factor 1-Alpha&apos; EquivalentTo &apos;E3 Ubiquitin-Protein Transferase&apos; and &apos;Transcription Regulatory Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Androgen Receptor Regulation Pathway&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Thyroid Gland Papillary Carcinoma&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Bromodomain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Ring Finger Domain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;TRIM Motif&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;PHD Finger&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Transcription Coactivator&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Activation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TRIM24 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Transcription Intermediary Factor 1-Alpha&apos; EquivalentTo &apos;E3 Ubiquitin-Protein Transferase&apos; and &apos;Transcription Regulatory Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Androgen Receptor Regulation Pathway&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Thyroid Gland Papillary Carcinoma&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Bromodomain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Ring Finger Domain&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;TRIM Motif&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;PHD Finger&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Transcription Coactivator&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;TRIM Family&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transcriptional Activation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TRIM24 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113505</classIRI>
<classLabel>t(9;11)</classLabel>
<deletedAxiom>&apos;t(9;11)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;t(9;11)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127775</classIRI>
<classLabel>Tenderness Indicator</classLabel>
<deletedAxiom>&apos;Tenderness Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Tenderness Indicator&apos; SubClassOf &apos;Symptom Indicator&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127774</classIRI>
<classLabel>Swollen Indicator</classLabel>
<deletedAxiom>&apos;Swollen Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Swollen Indicator&apos; SubClassOf &apos;Symptom Indicator&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127795</classIRI>
<classLabel>Number of Trial Sites within European Union State</classLabel>
<deletedAxiom>&apos;Number of Trial Sites within European Union State&apos; SubClassOf &apos;Quantity&apos;</deletedAxiom>
<newAxiom>&apos;Number of Trial Sites within European Union State&apos; SubClassOf &apos;Number&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127787</classIRI>
<classLabel>Total Number</classLabel>
<newAxiom>&apos;Total Number&apos; SubClassOf &apos;Number&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127553</classIRI>
<classLabel>Cusp Prolapse Indicator</classLabel>
<deletedAxiom>&apos;Cusp Prolapse Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Cusp Prolapse Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127550</classIRI>
<classLabel>Cusp Flail Indicator</classLabel>
<deletedAxiom>&apos;Cusp Flail Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Cusp Flail Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127548</classIRI>
<classLabel>Cusp Doming Indicator</classLabel>
<deletedAxiom>&apos;Cusp Doming Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Cusp Doming Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127560</classIRI>
<classLabel>Cusp Thickening Indicator</classLabel>
<deletedAxiom>&apos;Cusp Thickening Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Cusp Thickening Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127562</classIRI>
<classLabel>Chordae Tendineae Prolapse Indicator</classLabel>
<deletedAxiom>&apos;Chordae Tendineae Prolapse Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Chordae Tendineae Prolapse Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127556</classIRI>
<classLabel>Cusp Restricted Motion Indicator</classLabel>
<deletedAxiom>&apos;Cusp Restricted Motion Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Cusp Restricted Motion Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127558</classIRI>
<classLabel>Cusp Tethering Indicator</classLabel>
<deletedAxiom>&apos;Cusp Tethering Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Cusp Tethering Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127593</classIRI>
<classLabel>Systolic Anterior Motion Indicator</classLabel>
<deletedAxiom>&apos;Systolic Anterior Motion Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Systolic Anterior Motion Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95771</classIRI>
<classLabel>Primary Prostate Cancer Tissue/hTERT/Survivin mRNA-loaded Autologous Dendritic Cell Vaccine</classLabel>
<newAxiom>&apos;Primary Prostate Cancer Tissue/hTERT/Survivin mRNA-loaded Autologous Dendritic Cell Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95841</classIRI>
<classLabel>UBE4B Gene</classLabel>
<deletedAxiom>&apos;UBE4B Gene&apos; SubClassOf &apos;Regulatory Gene&apos;</deletedAxiom>
<newAxiom>&apos;UBE4B Gene&apos; SubClassOf &apos;Ubiquitin-Transferase Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81262</classIRI>
<classLabel>Medical Record Number</classLabel>
<deletedAxiom>&apos;Medical Record Number&apos; SubClassOf &apos;Number&apos;</deletedAxiom>
<newAxiom>&apos;Medical Record Number&apos; SubClassOf &apos;Identifier&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6325</classIRI>
<classLabel>Vaginal Verrucous Carcinoma</classLabel>
<deletedAxiom>&apos;Vaginal Verrucous Carcinoma&apos; EquivalentTo &apos;Verrucous Carcinoma&apos; and &apos;Vaginal Squamous Cell Carcinoma, Not Otherwise Specified&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Postcoital Bleeding&apos;)</deletedAxiom>
<newAxiom>&apos;Vaginal Verrucous Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180915 and &apos;Verrucous Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Postcoital Bleeding&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127049</classIRI>
<classLabel>t(10;17)(q22;p13)</classLabel>
<deletedAxiom>&apos;t(10;17)(q22;p13)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 17&apos;</deletedAxiom>
<newAxiom>&apos;t(10;17)(q22;p13)&apos; SubClassOf &apos;Chromosome 17 Abnormality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81728</classIRI>
<classLabel>Simultaneous Trisomies of Chromosomes 4, 10, and 17</classLabel>
<deletedAxiom>&apos;Simultaneous Trisomies of Chromosomes 4, 10, and 17&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 17&apos;</deletedAxiom>
<newAxiom>&apos;Simultaneous Trisomies of Chromosomes 4, 10, and 17&apos; SubClassOf &apos;Chromosome 17 Abnormality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179409</classIRI>
<classLabel>Anti-BCMA/Alpha-amanitin Antibody-drug Conjugate HDP-101</classLabel>
<deletedAxiom>&apos;Anti-BCMA/Alpha-amanitin Antibody-drug Conjugate HDP-101&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-BCMA/Alpha-amanitin Antibody-drug Conjugate HDP-101&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181108</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131490</classIRI>
<classLabel>ABL1 Gene Rearrangement</classLabel>
<deletedAxiom>&apos;ABL1 Gene Rearrangement&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;ABL1 Gene Rearrangement&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C106436</classIRI>
<classLabel>NOTCH3 Gene</classLabel>
<newAxiom>&apos;NOTCH3 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Infantile Myofibromatosis 2&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4167</classIRI>
<classLabel>Adrenal Cortex Mixed Cell Adenoma</classLabel>
<deletedAxiom>&apos;Adrenal Cortex Mixed Cell Adenoma&apos; EquivalentTo &apos;Mixed Neoplasm&apos; and &apos;Adrenal Cortex Adenoma&apos; and (&apos;Disease_Mapped_To_Gene&apos; some &apos;KCNJ5 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KCNJ5 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Adrenal Cortex Mixed Cell Adenoma&apos; EquivalentTo &apos;Mixed Cell Adenoma&apos; and &apos;Adrenal Cortex Adenoma&apos; and (&apos;Disease_Mapped_To_Gene&apos; some &apos;KCNJ5 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KCNJ5 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4157</classIRI>
<classLabel>Mixed Cell Adenoma</classLabel>
<deletedAxiom>&apos;Mixed Cell Adenoma&apos; EquivalentTo &apos;Adenoma&apos; and &apos;Mixed Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Mesenchymal Component Present&apos;)</deletedAxiom>
<newAxiom>&apos;Mixed Cell Adenoma&apos; EquivalentTo &apos;Adenoma&apos; and &apos;Mixed Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Mixed Neoplastic Epithelial Cell Population&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Mesenchymal Component Present&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179545</classIRI>
<classLabel>EGFR NM_005228.5:c.2609AG</classLabel>
<deletedAxiom>&apos;EGFR NM_005228.5:c.2609AG&apos; SubClassOf &apos;EGFR Activating Mutation&apos;</deletedAxiom>
<deletedAxiom>&apos;EGFR NM_005228.5:c.2609AG&apos; SubClassOf &apos;EGFR Exon 21 Mutation&apos;</deletedAxiom>
<newAxiom>&apos;EGFR NM_005228.5:c.2609AG&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180963</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C106525</classIRI>
<classLabel>Hemoglobin Distribution Width Measurement</classLabel>
<deletedAxiom>&apos;Hemoglobin Distribution Width Measurement&apos; SubClassOf &apos;Hematology Test&apos;</deletedAxiom>
<newAxiom>&apos;Hemoglobin Distribution Width Measurement&apos; SubClassOf &apos;Hemoglobin Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C106231</classIRI>
<classLabel>mRNA-derived Prostate Cancer Vaccine CV9104</classLabel>
<deletedAxiom>&apos;mRNA-derived Prostate Cancer Vaccine CV9104&apos; SubClassOf &apos;Antineoplastic Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;mRNA-derived Prostate Cancer Vaccine CV9104&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170915</classIRI>
<classLabel>Anti-BCMA Antibody-drug Conjugate CC-99712</classLabel>
<deletedAxiom>&apos;Anti-BCMA Antibody-drug Conjugate CC-99712&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-BCMA Antibody-drug Conjugate CC-99712&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181108</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131321</classIRI>
<classLabel>NTRK2 Gene Rearrangement</classLabel>
<deletedAxiom>&apos;NTRK2 Gene Rearrangement&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;NTRK2 Gene Rearrangement&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179342</classIRI>
<classLabel>PSMA-specific Targeting Module TMpPSMA</classLabel>
<newAxiom>&apos;PSMA-specific Targeting Module TMpPSMA&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170989</classIRI>
<classLabel>Concomitant or Additional Treatment Given Indicator</classLabel>
<deletedAxiom>&apos;Concomitant or Additional Treatment Given Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Concomitant or Additional Treatment Given Indicator&apos; SubClassOf &apos;Therapeutic Indicator&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C106035</classIRI>
<classLabel>Tripartite Motif-Containing Protein 16</classLabel>
<deletedAxiom>&apos;Tripartite Motif-Containing Protein 16&apos; EquivalentTo &apos;Regulatory Protein&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cytoplasm&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Keratinocyte&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Binding&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Keratinocyte Differentiation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Histone Acetylation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Keratinization Induction&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TRIM16 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Tripartite Motif-Containing Protein 16&apos; EquivalentTo &apos;E3 Ubiquitin-Protein Transferase&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cytoplasm&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Keratinocyte&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;TRIM Motif&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;TRIM Family&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;DNA Binding&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Keratinocyte Differentiation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Histone Acetylation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Keratinization Induction&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TRIM16 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170579</classIRI>
<classLabel>Soluble Complement C5b-9 Measurement</classLabel>
<deletedAxiom>&apos;Soluble Complement C5b-9 Measurement&apos; SubClassOf &apos;Complement Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Soluble Complement C5b-9 Measurement&apos; SubClassOf &apos;Complement C5b-9 Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4521</classIRI>
<classLabel>Vaginal Intraepithelial Neoplasia</classLabel>
<deletedAxiom>&apos;Vaginal Intraepithelial Neoplasia&apos; EquivalentTo &apos;Female Reproductive System Precancerous Condition&apos; and &apos;Vaginal Neoplasm&apos; and &apos;Intraepithelial Neoplasia&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Vagina&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Human Papillomavirus Infection&apos;)</deletedAxiom>
<newAxiom>&apos;Vaginal Intraepithelial Neoplasia&apos; EquivalentTo &apos;Female Reproductive System Precancerous Condition&apos; and &apos;Vaginal Squamous Neoplasm&apos; and &apos;Intraepithelial Neoplasia&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Vagina&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Human Papillomavirus Infection&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179107</classIRI>
<classLabel>Nezulcitinib</classLabel>
<deletedAxiom>&apos;Nezulcitinib&apos; SubClassOf &apos;JAK Inhibitor&apos;</deletedAxiom>
<newAxiom>&apos;Nezulcitinib&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4550</classIRI>
<classLabel>Conjunctival Melanoma</classLabel>
<deletedAxiom>&apos;Conjunctival Melanoma&apos; EquivalentTo &apos;Malignant Conjunctival Neoplasm&apos; and &apos;Ocular Melanoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Conjunctiva&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;BRAF NP_004324.2:p.V600X&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TERT Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KIT Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NRAS Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Conjunctival Melanoma&apos; EquivalentTo &apos;Malignant Conjunctival Neoplasm&apos; and &apos;Ocular Melanoma&apos; and &apos;Non-Cutaneous Melanoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Conjunctiva&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;BRAF NP_004324.2:p.V600X&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TERT Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KIT Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NRAS Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4553</classIRI>
<classLabel>Corneal Melanoma</classLabel>
<deletedAxiom>&apos;Corneal Melanoma&apos; EquivalentTo &apos;Malignant Corneal Neoplasm&apos; and &apos;Ocular Melanoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cornea&apos;)</deletedAxiom>
<newAxiom>&apos;Corneal Melanoma&apos; EquivalentTo &apos;Malignant Corneal Neoplasm&apos; and &apos;Ocular Melanoma&apos; and &apos;Non-Cutaneous Melanoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cornea&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170747</classIRI>
<classLabel>Autologous Anti-BCMA-CAR-4-1BB-CD3zeta-expressing T-cells C-CAR088</classLabel>
<deletedAxiom>&apos;Autologous Anti-BCMA-CAR-4-1BB-CD3zeta-expressing T-cells C-CAR088&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Anti-BCMA-CAR-4-1BB-CD3zeta-expressing T-cells C-CAR088&apos; SubClassOf &apos;Anti-BCMA-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4508</classIRI>
<classLabel>Ovarian Seromucinous Tumor</classLabel>
<deletedAxiom>&apos;Ovarian Seromucinous Tumor&apos; EquivalentTo &apos;Ovarian Epithelial Tumor&apos; and &apos;Mixed Neoplasm&apos; and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Transitional Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Serous Epithelial Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Epithelial Cell with Intracytoplasmic Mucin&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Neoplastic Glandular Epithelium Resembling the Normal Endometrium Present&apos;)</deletedAxiom>
<newAxiom>&apos;Ovarian Seromucinous Tumor&apos; EquivalentTo &apos;Ovarian Epithelial Tumor&apos; and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Transitional Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Serous Epithelial Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Epithelial Cell with Intracytoplasmic Mucin&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Neoplastic Glandular Epithelium Resembling the Normal Endometrium Present&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76404</classIRI>
<classLabel>Ticagrelor</classLabel>
<deletedAxiom>&apos;Ticagrelor&apos; SubClassOf &apos;Thienopyridine Antiplatelet Agent&apos;</deletedAxiom>
<newAxiom>&apos;Ticagrelor&apos; SubClassOf &apos;Antiplatelet Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C37190</classIRI>
<classLabel>t(9;22)(q22-31;q12)</classLabel>
<deletedAxiom>&apos;t(9;22)(q22-31;q12)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;t(9;22)(q22-31;q12)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170195</classIRI>
<classLabel>Nadorameran </classLabel>
<deletedAxiom>&apos;Nadorameran &apos; SubClassOf &apos;Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;Nadorameran &apos; SubClassOf &apos;mRNA Vaccine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159652</classIRI>
<classLabel>Pacanalotamab</classLabel>
<deletedAxiom>&apos;Pacanalotamab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Pacanalotamab&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181113</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C111574</classIRI>
<classLabel>mRNA-derived Lung Cancer Vaccine BI 1361849</classLabel>
<deletedAxiom>&apos;mRNA-derived Lung Cancer Vaccine BI 1361849&apos; SubClassOf &apos;Antineoplastic Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;mRNA-derived Lung Cancer Vaccine BI 1361849&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150827</classIRI>
<classLabel>Number of Occurrences</classLabel>
<deletedAxiom>&apos;Number of Occurrences&apos; SubClassOf &apos;Quantity&apos;</deletedAxiom>
<newAxiom>&apos;Number of Occurrences&apos; SubClassOf &apos;Number&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C111207</classIRI>
<classLabel>Hemoglobin A1C to Hemoglobin Ratio Measurement</classLabel>
<newAxiom>&apos;Hemoglobin A1C to Hemoglobin Ratio Measurement&apos; SubClassOf &apos;Hemoglobin Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C37890</classIRI>
<classLabel>t(9;22)(p24;q11)</classLabel>
<deletedAxiom>&apos;t(9;22)(p24;q11)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;t(9;22)(p24;q11)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C37885</classIRI>
<classLabel>t(9;12)(q34;p13)</classLabel>
<deletedAxiom>&apos;t(9;12)(q34;p13)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;t(9;12)(q34;p13)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C37887</classIRI>
<classLabel>t(9;12)(p24;p13)</classLabel>
<deletedAxiom>&apos;t(9;12)(p24;p13)&apos; SubClassOf &apos;Molecular_Abnormality_Involves_Gene&apos; some &apos;ETV6 Gene&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112288</classIRI>
<classLabel>Hemoglobin C Crystals Measurement</classLabel>
<deletedAxiom>&apos;Hemoglobin C Crystals Measurement&apos; SubClassOf &apos;Hematology Test&apos;</deletedAxiom>
<newAxiom>&apos;Hemoglobin C Crystals Measurement&apos; SubClassOf &apos;Hemoglobin Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112022</classIRI>
<classLabel>Surgical Organ or Space</classLabel>
<deletedAxiom>&apos;Surgical Organ or Space&apos; SubClassOf &apos;Anatomic Site&apos;</deletedAxiom>
<newAxiom>&apos;Surgical Organ or Space&apos; SubClassOf &apos;Surgical Site&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96616</classIRI>
<classLabel>Oxyhemoglobin Measurement</classLabel>
<deletedAxiom>&apos;Oxyhemoglobin Measurement&apos; SubClassOf &apos;Hematology Test&apos;</deletedAxiom>
<newAxiom>&apos;Oxyhemoglobin Measurement&apos; SubClassOf &apos;Hemoglobin Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96689</classIRI>
<classLabel>Methemoglobin Measurement</classLabel>
<deletedAxiom>&apos;Methemoglobin Measurement&apos; SubClassOf &apos;Hematology Test&apos;</deletedAxiom>
<newAxiom>&apos;Methemoglobin Measurement&apos; SubClassOf &apos;Hemoglobin Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96652</classIRI>
<classLabel>Glucose Clearance Measurement</classLabel>
<deletedAxiom>&apos;Glucose Clearance Measurement&apos; SubClassOf &apos;Chemistry Test&apos;</deletedAxiom>
<newAxiom>&apos;Glucose Clearance Measurement&apos; SubClassOf &apos;Glucose Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96739</classIRI>
<classLabel>Ovarian Cancer Stem Cell/hTERT/Survivin mRNAs-loaded Autologous Dendritic Cell Vaccine DC-006</classLabel>
<newAxiom>&apos;Ovarian Cancer Stem Cell/hTERT/Survivin mRNAs-loaded Autologous Dendritic Cell Vaccine DC-006&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126522</classIRI>
<classLabel>KIF20A Gene</classLabel>
<newAxiom>&apos;KIF20A Gene&apos; SubClassOf &apos;Cell Cycle Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126524</classIRI>
<classLabel>Kinesin-Like Protein KIF20A</classLabel>
<deletedAxiom>&apos;Kinesin-Like Protein KIF20A&apos; EquivalentTo &apos;Transport Protein&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Microtubule&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;ATPase&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Microtubule Associated Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cytokinesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;ATP Hydrolysis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Subcellular Protein Targeting&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;KIF20A Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Kinesin-Like Protein KIF20A&apos; EquivalentTo &apos;Transport Protein&apos; and &apos;Cell Cycle Protein&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Microtubule&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;ATPase&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Microtubule Associated Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cytokinesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;ATP Hydrolysis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Subcellular Protein Targeting&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;KIF20A Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82258</classIRI>
<classLabel>Alpha-1-Proteinase Inhibitor Human</classLabel>
<newAxiom>&apos;Alpha-1-Proteinase Inhibitor Human&apos; SubClassOf &apos;Protease Inhibitor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165656</classIRI>
<classLabel>Anti-BCMA/Anti-CD3 Bispecific Antibody REGN5459</classLabel>
<deletedAxiom>&apos;Anti-BCMA/Anti-CD3 Bispecific Antibody REGN5459&apos; SubClassOf &apos;Bispecific Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-BCMA/Anti-CD3 Bispecific Antibody REGN5459&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-BCMA/Anti-CD3 Bispecific Antibody REGN5459&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181114</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126056</classIRI>
<classLabel>Calcification Indicator</classLabel>
<deletedAxiom>&apos;Calcification Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Calcification Indicator&apos; SubClassOf &apos;Symptom Indicator&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82654</classIRI>
<classLabel>mRNA-Derived Prostate Cancer Vaccine CV9103</classLabel>
<deletedAxiom>&apos;mRNA-Derived Prostate Cancer Vaccine CV9103&apos; SubClassOf &apos;Vaccinia Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;mRNA-Derived Prostate Cancer Vaccine CV9103&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18142</classIRI>
<classLabel>Tandem Mass Spectrometry</classLabel>
<deletedAxiom>&apos;Tandem Mass Spectrometry&apos; SubClassOf &apos;Mass Spectrometry&apos;</deletedAxiom>
<newAxiom>&apos;Tandem Mass Spectrometry&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181005</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126126</classIRI>
<classLabel>KIF20B Gene</classLabel>
<newAxiom>&apos;KIF20B Gene&apos; SubClassOf &apos;Cell Cycle Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126128</classIRI>
<classLabel>Kinesin-Like Protein KIF20B</classLabel>
<deletedAxiom>&apos;Kinesin-Like Protein KIF20B&apos; EquivalentTo &apos;Transport Protein&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Microtubule&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Contractile System&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Centrosome&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;ATPase&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Microtubule Associated Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cytokinesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intracellular Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;ATP Hydrolysis&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;KIF20B Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Kinesin-Like Protein KIF20B&apos; EquivalentTo &apos;Transport Protein&apos; and &apos;Cell Cycle Protein&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Microtubule&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Contractile System&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Centrosome&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;ATPase&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Microtubule Associated Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cytokinesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intracellular Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;ATP Hydrolysis&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;KIF20B Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165478</classIRI>
<classLabel>Psoralen and Ultraviolet A (PUVA) Therapy Exposure</classLabel>
<deletedAxiom>&apos;Psoralen and Ultraviolet A (PUVA) Therapy Exposure&apos; SubClassOf &apos;Exposure&apos;</deletedAxiom>
<newAxiom>&apos;Psoralen and Ultraviolet A (PUVA) Therapy Exposure&apos; SubClassOf &apos;Radiation Exposure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179823</classIRI>
<classLabel>Hematoma Indicator</classLabel>
<deletedAxiom>&apos;Hematoma Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Hematoma Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179632</classIRI>
<classLabel>Anti-BCMA/Anti-CD3 Bispecific Antibody EMB-06</classLabel>
<newAxiom>&apos;Anti-BCMA/Anti-CD3 Bispecific Antibody EMB-06&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181114</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179670</classIRI>
<classLabel>Autologous CMV-pp65-LAMP mRNA Loaded Monocyte Vaccine MT-201-GBM</classLabel>
<newAxiom>&apos;Autologous CMV-pp65-LAMP mRNA Loaded Monocyte Vaccine MT-201-GBM&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165152</classIRI>
<classLabel>Study Site Investigator Identifier</classLabel>
<deletedAxiom>&apos;Study Site Investigator Identifier&apos; SubClassOf &apos;Identifier&apos;</deletedAxiom>
<newAxiom>&apos;Study Site Investigator Identifier&apos; SubClassOf &apos;Investigator Identifier&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C154158</classIRI>
<classLabel>FGFR1 Positive</classLabel>
<newAxiom>&apos;FGFR1 Positive&apos; SubClassOf &apos;Receptor Status&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168865</classIRI>
<classLabel>Number of Intended Intrathecal Chemotherapy Doses</classLabel>
<deletedAxiom>&apos;Number of Intended Intrathecal Chemotherapy Doses&apos; SubClassOf &apos;Number&apos;</deletedAxiom>
<newAxiom>&apos;Number of Intended Intrathecal Chemotherapy Doses&apos; SubClassOf &apos;Number of Doses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C154274</classIRI>
<classLabel>mRNA-based TriMix Melanoma Vaccine ECI-006</classLabel>
<newAxiom>&apos;mRNA-based TriMix Melanoma Vaccine ECI-006&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120661</classIRI>
<classLabel>Sjogrens SS-A52 Antibody Measurement</classLabel>
<deletedAxiom>&apos;Sjogrens SS-A52 Antibody Measurement&apos; SubClassOf &apos;Immunology Test&apos;</deletedAxiom>
<newAxiom>&apos;Sjogrens SS-A52 Antibody Measurement&apos; SubClassOf &apos;Sjogren&apos;s SS-A Antibody Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120662</classIRI>
<classLabel>Sjogrens SS-A60 Antibody Measurement</classLabel>
<deletedAxiom>&apos;Sjogrens SS-A60 Antibody Measurement&apos; SubClassOf &apos;Immunology Test&apos;</deletedAxiom>
<newAxiom>&apos;Sjogrens SS-A60 Antibody Measurement&apos; SubClassOf &apos;Sjogren&apos;s SS-A Antibody Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120393</classIRI>
<classLabel>Pro-Opiomelanocortin Deficiency</classLabel>
<newAxiom>&apos;Pro-Opiomelanocortin Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;POMC Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120394</classIRI>
<classLabel>Melanocortin 4 Receptor Deficiency</classLabel>
<newAxiom>&apos;Melanocortin 4 Receptor Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;MC4R Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120386</classIRI>
<classLabel>Leptin Receptor Deficiency</classLabel>
<newAxiom>&apos;Leptin Receptor Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;LEPR Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120384</classIRI>
<classLabel>Leptin Deficiency</classLabel>
<newAxiom>&apos;Leptin Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;LEP Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120385</classIRI>
<classLabel>Brain-Derived Neurotropic Factor Deficiency</classLabel>
<newAxiom>&apos;Brain-Derived Neurotropic Factor Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;BDNF Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77676</classIRI>
<classLabel>Application Site</classLabel>
<deletedAxiom>&apos;Application Site&apos; SubClassOf &apos;Anatomic Site&apos;</deletedAxiom>
<newAxiom>&apos;Application Site&apos; SubClassOf &apos;Targeted Anatomic Site&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120406</classIRI>
<classLabel>Neurotropic Tyrosine Kinase Receptor Type 2 Deficiency</classLabel>
<newAxiom>&apos;Neurotropic Tyrosine Kinase Receptor Type 2 Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;NTRK2 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120407</classIRI>
<classLabel>Prohormone Convertase 1 Deficiency</classLabel>
<newAxiom>&apos;Prohormone Convertase 1 Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;PCSK1 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120039</classIRI>
<classLabel>Antigen-targeted Personalized Breast Cancer Vaccine</classLabel>
<deletedAxiom>&apos;Antigen-targeted Personalized Breast Cancer Vaccine&apos; SubClassOf &apos;Antineoplastic Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;Antigen-targeted Personalized Breast Cancer Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38629</classIRI>
<classLabel>Lower Extremity Part</classLabel>
<newAxiom>&apos;Lower Extremity Part&apos; SubClassOf &apos;Anatomic_Structure_Is_Physical_Part_Of&apos; some &apos;Lower Extremity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38628</classIRI>
<classLabel>Upper Extremity Part</classLabel>
<newAxiom>&apos;Upper Extremity Part&apos; SubClassOf &apos;Anatomic_Structure_Is_Physical_Part_Of&apos; some &apos;Upper Extremity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173861</classIRI>
<classLabel>ROS1 Gene Mutation Negative</classLabel>
<newAxiom>&apos;ROS1 Gene Mutation Negative&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180950</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173862</classIRI>
<classLabel>NTRK Family Gene Mutation Negative</classLabel>
<newAxiom>&apos;NTRK Family Gene Mutation Negative&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180949</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173851</classIRI>
<classLabel>Zorecimeran</classLabel>
<deletedAxiom>&apos;Zorecimeran&apos; SubClassOf &apos;COVID-19 Vaccine&apos;</deletedAxiom>
<deletedAxiom>&apos;Zorecimeran&apos; SubClassOf &apos;mRNA Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;Zorecimeran&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181140</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173968</classIRI>
<classLabel>Autologous Pancreatic Adenocarcinoma Lysate and mRNA-loaded Dendritic Cell Vaccine</classLabel>
<newAxiom>&apos;Autologous Pancreatic Adenocarcinoma Lysate and mRNA-loaded Dendritic Cell Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148515</classIRI>
<classLabel>Advanced Uveal Melanoma</classLabel>
<deletedAxiom>&apos;Advanced Uveal Melanoma&apos; EquivalentTo &apos;Metastatic Uveal Melanoma&apos; and &apos;Advanced Melanoma&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Uveal Melanoma&apos; EquivalentTo &apos;Metastatic Uveal Melanoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180895</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148506</classIRI>
<classLabel>Autologous BCMA-4-1BBz-targeted CAR T-cells</classLabel>
<deletedAxiom>&apos;Autologous BCMA-4-1BBz-targeted CAR T-cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous BCMA-4-1BBz-targeted CAR T-cells&apos; SubClassOf &apos;Anti-BCMA-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97417</classIRI>
<classLabel>Clathrin Heavy Chain 2</classLabel>
<deletedAxiom>&apos;Clathrin Heavy Chain 2&apos; EquivalentTo &apos;Structural Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Huntington&apos;s Disease Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Lysosome Assembly Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Endocytosis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Bacterial Invasion of Epithelial Cell Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Membrane Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Receptor Mediated Endocytosis&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CLTCL1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Clathrin Heavy Chain 2&apos; EquivalentTo &apos;Structural Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Huntington&apos;s Disease Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Lysosome Assembly Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Endocytosis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Bacterial Invasion of Epithelial Cell Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Membrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Coated Pit&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Receptor Mediated Endocytosis&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CLTCL1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97414</classIRI>
<classLabel>Clathrin Heavy Chain 1</classLabel>
<deletedAxiom>&apos;Clathrin Heavy Chain 1&apos; EquivalentTo &apos;Structural Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Huntington&apos;s Disease Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Lysosome Assembly Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Endocytosis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Arf6 Trafficking Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;FAS Signaling Pathway PID&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Bacterial Invasion of Epithelial Cell Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Membrane Protein&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Receptor Mediated Endocytosis&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CLTC Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Clathrin Heavy Chain 1&apos; EquivalentTo &apos;Structural Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Huntington&apos;s Disease Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Lysosome Assembly Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Endocytosis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Arf6 Trafficking Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;FAS Signaling Pathway PID&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Bacterial Invasion of Epithelial Cell Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Membrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Coated Pit&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Receptor Mediated Endocytosis&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CLTC Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148498</classIRI>
<classLabel>Ciltacabtagene Autoleucel</classLabel>
<deletedAxiom>&apos;Ciltacabtagene Autoleucel&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Ciltacabtagene Autoleucel&apos; SubClassOf &apos;Anti-BCMA-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C24667</classIRI>
<classLabel>PDGFRB Gene</classLabel>
<newAxiom>&apos;PDGFRB Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Infantile Myofibromatosis 1&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83085</classIRI>
<classLabel>Concomitant Medication Use Indication</classLabel>
<deletedAxiom>&apos;Concomitant Medication Use Indication&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Concomitant Medication Use Indication&apos; SubClassOf &apos;Therapeutic Indicator&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83197</classIRI>
<classLabel>Adverse Event Body System or Organ Class</classLabel>
<deletedAxiom>&apos;Adverse Event Body System or Organ Class&apos; SubClassOf &apos;Other Anatomic Concept&apos;</deletedAxiom>
<newAxiom>&apos;Adverse Event Body System or Organ Class&apos; SubClassOf &apos;Organ System&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C135010</classIRI>
<classLabel>CDISC SDTM Pharmacogenomics/Genetics Methods and Supporting Information Test Code Terminology</classLabel>
<deletedAxiom>&apos;CDISC SDTM Pharmacogenomics/Genetics Methods and Supporting Information Test Code Terminology&apos; SubClassOf &apos;CDISC SDTM Terminology&apos;</deletedAxiom>
<newAxiom>&apos;CDISC SDTM Pharmacogenomics/Genetics Methods and Supporting Information Test Code Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C135011</classIRI>
<classLabel>CDISC SDTM Pharmacogenomics/Genetics Methods and Supporting Information Test Name Terminology</classLabel>
<deletedAxiom>&apos;CDISC SDTM Pharmacogenomics/Genetics Methods and Supporting Information Test Name Terminology&apos; SubClassOf &apos;CDISC SDTM Terminology&apos;</deletedAxiom>
<newAxiom>&apos;CDISC SDTM Pharmacogenomics/Genetics Methods and Supporting Information Test Name Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174339</classIRI>
<classLabel>Mycolicibacterium mucogenicum</classLabel>
<deletedAxiom>&apos;Mycolicibacterium mucogenicum&apos; SubClassOf &apos;Mycobacterium&apos;</deletedAxiom>
<newAxiom>&apos;Mycolicibacterium mucogenicum&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>t(1;16)(p34;p11)</classLabel>
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<newAxiom>&apos;t(1;16)(p34;p11)&apos; SubClassOf &apos;Chromosome 1 Abnormality&apos;</newAxiom>
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<deletedAxiom>&apos;Liposome-encapsulated TAAs mRNA Vaccine W_ova1&apos; SubClassOf &apos;Antineoplastic Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;Liposome-encapsulated TAAs mRNA Vaccine W_ova1&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
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<newAxiom>&apos;Retinal Melanoma&apos; EquivalentTo &apos;Malignant Retinal Neoplasm&apos; and &apos;Ocular Melanoma&apos; and &apos;Non-Cutaneous Melanoma&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Retina&apos;)</newAxiom>
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<classLabel>Personalized Cancer Vaccine RO7198457</classLabel>
<deletedAxiom>&apos;Personalized Cancer Vaccine RO7198457&apos; SubClassOf &apos;Antineoplastic Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;Personalized Cancer Vaccine RO7198457&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
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<classLabel>Phenoxybenzamine Hydrochloride</classLabel>
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<changedClass>
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<newAxiom>&apos;Mass Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
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<classLabel>Ecchymosis Indicator</classLabel>
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<newAxiom>&apos;Ecchymosis Indicator&apos; SubClassOf &apos;Symptom Indicator&apos;</newAxiom>
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<changedClass>
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<classLabel>Edema Indicator</classLabel>
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<newAxiom>&apos;Edema Indicator&apos; SubClassOf &apos;Symptom Indicator&apos;</newAxiom>
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<changedClass>
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<classLabel>Pustule Indicator</classLabel>
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<newAxiom>&apos;Pustule Indicator&apos; SubClassOf &apos;Symptom Indicator&apos;</newAxiom>
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<classLabel>Bartholin&apos;s Gland Abnormality Indicator</classLabel>
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<newAxiom>&apos;Bartholin&apos;s Gland Abnormality Indicator&apos; SubClassOf &apos;Abnormal Indicator&apos;</newAxiom>
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<changedClass>
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<classLabel>Ulcer Indicator</classLabel>
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<newAxiom>&apos;Ulcer Indicator&apos; SubClassOf &apos;Symptom Indicator&apos;</newAxiom>
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<classLabel>Abnormal Bleeding Indicator</classLabel>
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<newAxiom>&apos;Abnormal Bleeding Indicator&apos; SubClassOf &apos;Abnormal Indicator&apos;</newAxiom>
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<newAxiom>&apos;Glycoprotein Hormones Alpha Chain Protein&apos; EquivalentTo &apos;Peptide Hormone&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Neuroactive Ligand-Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Gonadotropin-Releasing Hormone Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Autoimmune Thyroid Disease Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Extracellular Space&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181076) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Human Chorionic Gonadotropin&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Thyroid-Stimulating Hormone&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;G Protein-Coupled Receptor Signaling&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;CGA Gene&apos;)</newAxiom>
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<newAxiom>&apos;t(8;9)(p22;p24.1)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
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<classLabel>Cancer Primary Site Known Indicator</classLabel>
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<newAxiom>&apos;Cancer Primary Site Known Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
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<classLabel>Skene&apos;s Gland Abnormality Indicator</classLabel>
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<newAxiom>&apos;Skene&apos;s Gland Abnormality Indicator&apos; SubClassOf &apos;Abnormal Indicator&apos;</newAxiom>
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<classLabel>Erythema Indicator</classLabel>
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<newAxiom>&apos;Erythema Indicator&apos; SubClassOf &apos;Symptom Indicator&apos;</newAxiom>
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<newAxiom>&apos;Rash Indicator&apos; SubClassOf &apos;Symptom Indicator&apos;</newAxiom>
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<classLabel>KRAS NM_004985.3:c.436GA</classLabel>
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<deletedAxiom>&apos;Autologous Bladder Cell Carcinoma RNAs/CD40L RNA Electroporated Autologous Matured Dendritic Cells&apos; SubClassOf &apos;Antineoplastic Immune Cell&apos;</deletedAxiom>
<newAxiom>&apos;Autologous Bladder Cell Carcinoma RNAs/CD40L RNA Electroporated Autologous Matured Dendritic Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
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<changedClass>
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<classLabel>Stress Response Signaling</classLabel>
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<classLabel>Autologous OFA-iLRP RNA-Transfected Dendritic Cell Vaccine</classLabel>
<newAxiom>&apos;Autologous OFA-iLRP RNA-Transfected Dendritic Cell Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
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<classLabel>Anatomic Site of Origin for Matched Normal Tissue</classLabel>
<deletedAxiom>&apos;Anatomic Site of Origin for Matched Normal Tissue&apos; SubClassOf &apos;Anatomic Site&apos;</deletedAxiom>
<newAxiom>&apos;Anatomic Site of Origin for Matched Normal Tissue&apos; SubClassOf &apos;Sample Anatomic Site&apos;</newAxiom>
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<changedClass>
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<classLabel>PTCH1 Gene Deletion</classLabel>
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<newAxiom>&apos;PTCH1 Gene Deletion&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
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<changedClass>
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<classLabel>Fabric</classLabel>
<deletedAxiom>&apos;Fabric&apos; SubClassOf &apos;Device Component or Accessory&apos;</deletedAxiom>
<newAxiom>&apos;Fabric&apos; SubClassOf &apos;Material&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C64798</classIRI>
<classLabel>Erythrocyte Mean Corpuscular Hemoglobin Concentration</classLabel>
<deletedAxiom>&apos;Erythrocyte Mean Corpuscular Hemoglobin Concentration&apos; SubClassOf &apos;Hematology Test&apos;</deletedAxiom>
<newAxiom>&apos;Erythrocyte Mean Corpuscular Hemoglobin Concentration&apos; SubClassOf &apos;Hemoglobin Measurement&apos;</newAxiom>
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<newAxiom>&apos;Erythrocyte Mean Corpuscular Hemoglobin&apos; SubClassOf &apos;Hemoglobin Measurement&apos;</newAxiom>
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<changedClass>
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<classLabel>Loss of Chromosome 9q</classLabel>
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<newAxiom>&apos;Loss of Chromosome 9q&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
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<newAxiom>&apos;Carcinoma of Skene Glands&apos; EquivalentTo &apos;Adenocarcinoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Skene Gland&apos;)</newAxiom>
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<newAxiom>&apos;Primary Tumor Site Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
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<newAxiom>&apos;Juvenile Diabetes Foundation Unit&apos; SubClassOf &apos;Unit of Biological and Biochemical Measurement&apos;</newAxiom>
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<deletedAxiom>&apos;Lipid Nanoparticle-encapsulated mRNA-based SARS-CoV-2 Vaccine mRNA-1273&apos; SubClassOf &apos;mRNA Vaccine&apos;</deletedAxiom>
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<deletedAxiom>&apos;CDISC SDTM Pharmacogenomics Biomarker Medical Statement Terminology&apos; SubClassOf &apos;CDISC SDTM Terminology&apos;</deletedAxiom>
<newAxiom>&apos;CDISC SDTM Pharmacogenomics Biomarker Medical Statement Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</newAxiom>
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<classLabel>TSC1 Gene Rearrangement</classLabel>
<deletedAxiom>&apos;TSC1 Gene Rearrangement&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;TSC1 Gene Rearrangement&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
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<changedClass>
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<classLabel>Uveal Melanoma</classLabel>
<deletedAxiom>&apos;Uveal Melanoma&apos; EquivalentTo &apos;Malignant Uveal Neoplasm&apos; and &apos;Ocular Melanoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Uvea&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BAP1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;GNAQ Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;GNA11 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;BAP1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;SF3B1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CYSLTR2 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PLCB4 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EIF1AX Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;GNAQ Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;GNA11 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Uveal Melanoma&apos; EquivalentTo &apos;Malignant Uveal Neoplasm&apos; and &apos;Ocular Melanoma&apos; and &apos;Non-Cutaneous Melanoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Uvea&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BAP1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;GNAQ Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;GNA11 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;BAP1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;SF3B1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CYSLTR2 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PLCB4 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EIF1AX Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;GNAQ Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;GNA11 Gene Mutation&apos;)</newAxiom>
</changedClass>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7736</classIRI>
<classLabel>Vaginal Squamous Cell Carcinoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Vaginal Squamous Cell Carcinoma, Not Otherwise Specified&apos; EquivalentTo &apos;Squamous Cell Carcinoma&apos; and &apos;Vaginal Carcinoma&apos; and &apos;Vaginal Squamous Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Vaginal Squamous Cell Carcinoma, Not Otherwise Specified&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180915 and (&apos;Disease_Has_Finding&apos; some &apos;p16 Immunohistochemistry or HPV Testing Status Unknown&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128060</classIRI>
<classLabel>Vaginal Papillary Carcinoma</classLabel>
<deletedAxiom>&apos;Vaginal Papillary Carcinoma&apos; EquivalentTo &apos;Papillary Squamous Cell Carcinoma&apos; and &apos;Vaginal Squamous Cell Carcinoma, Not Otherwise Specified&apos; and (&apos;Disease_Excludes_Finding&apos; some &apos;Pushing Tumor Margin&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Koilocytotic Atypia&apos;)</deletedAxiom>
<newAxiom>&apos;Vaginal Papillary Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180915 and &apos;Papillary Squamous Cell Carcinoma&apos; and (&apos;Disease_Excludes_Finding&apos; some &apos;Pushing Tumor Margin&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Koilocytotic Atypia&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142108</classIRI>
<classLabel>CTLA4 Positive</classLabel>
<newAxiom>&apos;CTLA4 Positive&apos; SubClassOf &apos;Receptor Status&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90144</classIRI>
<classLabel>Cytochrome C Oxidase Assembly Protein COX11, Mitochondrial</classLabel>
<deletedAxiom>&apos;Cytochrome C Oxidase Assembly Protein COX11, Mitochondrial&apos; EquivalentTo &apos;Ligand Binding Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Oxidative Phosphorylation Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Mitochondrion&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Inner Mitochondrial Membrane&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;All Sites&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Cytochrome C Oxidase&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Energy Metabolism Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;COX11 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Cytochrome C Oxidase Assembly Protein COX11, Mitochondrial&apos; EquivalentTo &apos;Ligand Binding Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Oxidative Phosphorylation Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Mitochondrion&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Inner Mitochondrial Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Electron-Transport Chain of the Respiratory Enzymes&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;All Sites&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Cytochrome C Oxidase&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Energy Metabolism Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;COX11 Gene&apos;)</newAxiom>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C117116</classIRI>
<classLabel>t(9;22)</classLabel>
<deletedAxiom>&apos;t(9;22)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;t(9;22)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</newAxiom>
</changedClass>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C117291</classIRI>
<classLabel>PSMA-targeted Tubulysin B-containing Conjugate EC1169</classLabel>
<deletedAxiom>&apos;PSMA-targeted Tubulysin B-containing Conjugate EC1169&apos; SubClassOf &apos;Radioconjugate&apos;</deletedAxiom>
<newAxiom>&apos;PSMA-targeted Tubulysin B-containing Conjugate EC1169&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</newAxiom>
<newAxiom>&apos;PSMA-targeted Tubulysin B-containing Conjugate EC1169&apos; SubClassOf &apos;Immunoconjugate&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156860</classIRI>
<classLabel>Number of Days from Date of Initial Cancer Diagnosis to Date of Additional Surgery for New Tumor Event</classLabel>
<deletedAxiom>&apos;Number of Days from Date of Initial Cancer Diagnosis to Date of Additional Surgery for New Tumor Event&apos; SubClassOf &apos;CPTAC Questions&apos;</deletedAxiom>
<newAxiom>&apos;Number of Days from Date of Initial Cancer Diagnosis to Date of Additional Surgery for New Tumor Event&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181040</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142244</classIRI>
<classLabel>Cardiac Valvular Stenosis Indicator</classLabel>
<deletedAxiom>&apos;Cardiac Valvular Stenosis Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Cardiac Valvular Stenosis Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156856</classIRI>
<classLabel>Number of Days from Date of Initial Cancer Diagnosis to Date of New Tumor Event after Initial Treatment</classLabel>
<deletedAxiom>&apos;Number of Days from Date of Initial Cancer Diagnosis to Date of New Tumor Event after Initial Treatment&apos; SubClassOf &apos;Number&apos;</deletedAxiom>
<newAxiom>&apos;Number of Days from Date of Initial Cancer Diagnosis to Date of New Tumor Event after Initial Treatment&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181040</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156857</classIRI>
<classLabel>Number of Days from Date of Initial Pathologic Diagnosis to Date of Additional Surgery for New Tumor Event</classLabel>
<deletedAxiom>&apos;Number of Days from Date of Initial Pathologic Diagnosis to Date of Additional Surgery for New Tumor Event&apos; SubClassOf &apos;Number&apos;</deletedAxiom>
<newAxiom>&apos;Number of Days from Date of Initial Pathologic Diagnosis to Date of Additional Surgery for New Tumor Event&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181040</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156504</classIRI>
<classLabel>Bowel Perforation Indicator</classLabel>
<deletedAxiom>&apos;Bowel Perforation Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Bowel Perforation Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156503</classIRI>
<classLabel>Bowel Obstruction Indicator</classLabel>
<deletedAxiom>&apos;Bowel Obstruction Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Bowel Obstruction Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156505</classIRI>
<classLabel>Lymphovascular Invasion Indicator</classLabel>
<deletedAxiom>&apos;Lymphovascular Invasion Indicator&apos; SubClassOf &apos;Indicator&apos;</deletedAxiom>
<newAxiom>&apos;Lymphovascular Invasion Indicator&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90560</classIRI>
<classLabel>Autologous TriMix-DC Melanoma Vaccine</classLabel>
<newAxiom>&apos;Autologous TriMix-DC Melanoma Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26027</classIRI>
<classLabel>Cytochrome C Oxidase Subunit 6C</classLabel>
<deletedAxiom>&apos;Cytochrome C Oxidase Subunit 6C&apos; EquivalentTo &apos;Regulatory Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Alzheimer&apos;s Disease Pathway KEGG&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Huntington&apos;s Disease Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Oxidative Phosphorylation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Parkinson&apos;s Disease Pathway KEGG&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cardiac Muscle Contraction Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Mitochondrion&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Inner Mitochondrial Membrane&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;All Sites&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Cytochrome C Oxidase&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Energy Metabolism Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;COX6C Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Cytochrome C Oxidase Subunit 6C&apos; EquivalentTo &apos;Regulatory Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Alzheimer&apos;s Disease Pathway KEGG&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Huntington&apos;s Disease Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Oxidative Phosphorylation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Parkinson&apos;s Disease Pathway KEGG&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cardiac Muscle Contraction Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Mitochondrion&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Inner Mitochondrial Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Electron-Transport Chain of the Respiratory Enzymes&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;All Sites&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some &apos;Cytochrome C Oxidase&apos;) and (&apos;Gene_Product_Has_Biochemical_Function&apos; some &apos;Protein Complex Subunit&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Energy Metabolism Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;COX6C Gene&apos;)</newAxiom>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26034</classIRI>
<classLabel>Cytochrome C Oxidase</classLabel>
<newAxiom>&apos;Cytochrome C Oxidase&apos; SubClassOf &apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Electron-Transport Chain of the Respiratory Enzymes&apos;</newAxiom>
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<changedClass>
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<classLabel>Days between Diagnosis and Death</classLabel>
<deletedAxiom>&apos;Days between Diagnosis and Death&apos; SubClassOf &apos;Number&apos;</deletedAxiom>
<newAxiom>&apos;Days between Diagnosis and Death&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181060</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156418</classIRI>
<classLabel>Days Between Birth and Diagnosis</classLabel>
<deletedAxiom>&apos;Days Between Birth and Diagnosis&apos; SubClassOf &apos;Number&apos;</deletedAxiom>
<newAxiom>&apos;Days Between Birth and Diagnosis&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181061</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156417</classIRI>
<classLabel>Days Between Diagnosis and Treatment</classLabel>
<deletedAxiom>&apos;Days Between Diagnosis and Treatment&apos; SubClassOf &apos;Number&apos;</deletedAxiom>
<newAxiom>&apos;Days Between Diagnosis and Treatment&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181040</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99116</classIRI>
<classLabel>hTERT mRNA/Survivin Peptide-double-loaded Autologous Dendritic Cell Vaccine</classLabel>
<newAxiom>&apos;hTERT mRNA/Survivin Peptide-double-loaded Autologous Dendritic Cell Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99114</classIRI>
<classLabel>TRP2 mRNA-electroporated Autologous Langerhans-type Dendritic Cell Vaccine</classLabel>
<newAxiom>&apos;TRP2 mRNA-electroporated Autologous Langerhans-type Dendritic Cell Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156052</classIRI>
<classLabel>BCMA x CD3 T-cell Engaging Antibody CC-93269</classLabel>
<deletedAxiom>&apos;BCMA x CD3 T-cell Engaging Antibody CC-93269&apos; SubClassOf &apos;Bispecific Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;BCMA x CD3 T-cell Engaging Antibody CC-93269&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;BCMA x CD3 T-cell Engaging Antibody CC-93269&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181114</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156067</classIRI>
<classLabel>Autologous CMV-pp65-flLAMP mRNA Loaded Dendritic Cell Vaccine</classLabel>
<newAxiom>&apos;Autologous CMV-pp65-flLAMP mRNA Loaded Dendritic Cell Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99287</classIRI>
<classLabel>Product Reference Number</classLabel>
<deletedAxiom>&apos;Product Reference Number&apos; SubClassOf &apos;Number&apos;</deletedAxiom>
<newAxiom>&apos;Product Reference Number&apos; SubClassOf &apos;Product Identifier&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99286</classIRI>
<classLabel>Catalog Number</classLabel>
<deletedAxiom>&apos;Catalog Number&apos; SubClassOf &apos;Number&apos;</deletedAxiom>
<newAxiom>&apos;Catalog Number&apos; SubClassOf &apos;Identifier&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99285</classIRI>
<classLabel>Model Number</classLabel>
<deletedAxiom>&apos;Model Number&apos; SubClassOf &apos;Number&apos;</deletedAxiom>
<newAxiom>&apos;Model Number&apos; SubClassOf &apos;Identifier&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90964</classIRI>
<classLabel>Human Interleukin-10</classLabel>
<deletedAxiom>&apos;Human Interleukin-10&apos; SubClassOf &apos;Recombinant Interleukin&apos;</deletedAxiom>
<newAxiom>&apos;Human Interleukin-10&apos; SubClassOf &apos;Recombinant Interleukin 10&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26618</classIRI>
<classLabel>Alpha Granule</classLabel>
<deletedAxiom>&apos;Alpha Granule&apos; SubClassOf &apos;Other Anatomic Concept&apos;</deletedAxiom>
<newAxiom>&apos;Alpha Granule&apos; SubClassOf &apos;Cell Part&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C51654</classIRI>
<classLabel>Stereotactic Biopsy</classLabel>
<deletedAxiom>&apos;Stereotactic Biopsy&apos; SubClassOf &apos;Biopsy&apos;</deletedAxiom>
<newAxiom>&apos;Stereotactic Biopsy&apos; SubClassOf &apos;Image Guided Biopsy&apos;</newAxiom>
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<newAxiom>'Level 4 Metabolite Identification Confidence' SubClassOf 'Metabolite Identification Confidence Level'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181009</classIRI>
<classLabel>Level 3 Metabolite Identification Confidence</classLabel>
<newAxiom>'Level 3 Metabolite Identification Confidence' SubClassOf 'Metabolite Identification Confidence Level'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181008</classIRI>
<classLabel>Level 2 Metabolite Identification Confidence</classLabel>
<newAxiom>'Level 2 Metabolite Identification Confidence' SubClassOf 'Metabolite Identification Confidence Level'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181007</classIRI>
<classLabel>Level 1 Metabolite Identification Confidence</classLabel>
<newAxiom>'Level 1 Metabolite Identification Confidence' SubClassOf 'Metabolite Identification Confidence Level'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181006</classIRI>
<classLabel>Metabolite Identification Confidence Level</classLabel>
<newAxiom>'Metabolite Identification Confidence Level' SubClassOf 'Classification'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181005</classIRI>
<classLabel>Sequential Mass Spectrometry</classLabel>
<newAxiom>'Sequential Mass Spectrometry' SubClassOf 'Mass Spectrometry'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181004</classIRI>
<classLabel>MRI Quantification of Liver Iron Concentration</classLabel>
<newAxiom>'MRI Quantification of Liver Iron Concentration' SubClassOf 'Magnetic Resonance Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181003</classIRI>
<classLabel>Dysmetria</classLabel>
<newAxiom>'Dysmetria' SubClassOf 'Neurological Signs and Symptoms'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181002</classIRI>
<classLabel>Joubert Syndrome 9</classLabel>
<newAxiom>'Joubert Syndrome 9' SubClassOf 'Joubert Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181001</classIRI>
<classLabel>Mental Retardation, X-Linked Syndromic, Christianson Type</classLabel>
<newAxiom>'Mental Retardation, X-Linked Syndromic, Christianson Type' SubClassOf 'Mental Retardation'</newAxiom>
<newAxiom>'Mental Retardation, X-Linked Syndromic, Christianson Type' SubClassOf 'Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181000</classIRI>
<classLabel>Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2Y</classLabel>
<newAxiom>'Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2Y' SubClassOf 'Limb-Girdle Muscular Dystrophy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181099</classIRI>
<classLabel>METTL14 Gene</classLabel>
<newAxiom>'METTL14 Gene' SubClassOf 'Regulatory Gene'</newAxiom>
<newAxiom>'METTL14 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Processing'</newAxiom>
<newAxiom>'METTL14 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Methylation'</newAxiom>
<newAxiom>'METTL14 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Translational Regulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181098</classIRI>
<classLabel>N6-Adenosine-Methyltransferase Non-Catalytic Subunit</classLabel>
<newAxiom>'N6-Adenosine-Methyltransferase Non-Catalytic Subunit' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Nucleus'</newAxiom>
<newAxiom>'N6-Adenosine-Methyltransferase Non-Catalytic Subunit' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Processing'</newAxiom>
<newAxiom>'N6-Adenosine-Methyltransferase Non-Catalytic Subunit' SubClassOf 'Regulatory Protein'</newAxiom>
<newAxiom>'N6-Adenosine-Methyltransferase Non-Catalytic Subunit' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Translational Regulation'</newAxiom>
<newAxiom>'N6-Adenosine-Methyltransferase Non-Catalytic Subunit' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'METTL14 Gene'</newAxiom>
<newAxiom>'N6-Adenosine-Methyltransferase Non-Catalytic Subunit' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Methylation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181097</classIRI>
<classLabel>N6-Adenosine-Methyltransferase Catalytic Subunit</classLabel>
<newAxiom>'N6-Adenosine-Methyltransferase Catalytic Subunit' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Nucleus'</newAxiom>
<newAxiom>'N6-Adenosine-Methyltransferase Catalytic Subunit' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'METTL3 Gene'</newAxiom>
<newAxiom>'N6-Adenosine-Methyltransferase Catalytic Subunit' SubClassOf 'Methyltransferase'</newAxiom>
<newAxiom>'N6-Adenosine-Methyltransferase Catalytic Subunit' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Translational Regulation'</newAxiom>
<newAxiom>'N6-Adenosine-Methyltransferase Catalytic Subunit' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Processing'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181096</classIRI>
<classLabel>METTL3 wt Allele</classLabel>
<newAxiom>'METTL3 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '14q11.2'</newAxiom>
<newAxiom>'METTL3 wt Allele' SubClassOf 'METTL3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181095</classIRI>
<classLabel>METTL3 Gene</classLabel>
<newAxiom>'METTL3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Processing'</newAxiom>
<newAxiom>'METTL3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Translational Regulation'</newAxiom>
<newAxiom>'METTL3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Methylation'</newAxiom>
<newAxiom>'METTL3 Gene' SubClassOf 'Methyltransferase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181094</classIRI>
<classLabel>Oncolytic Virus CF33-expressing hNIS/Anti-PD-L1 Antibody</classLabel>
<newAxiom>'Oncolytic Virus CF33-expressing hNIS/Anti-PD-L1 Antibody' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
<newAxiom>'Oncolytic Virus CF33-expressing hNIS/Anti-PD-L1 Antibody' SubClassOf 'Gene Transfer or Gene Delivery Agent'</newAxiom>
<newAxiom>'Oncolytic Virus CF33-expressing hNIS/Anti-PD-L1 Antibody' SubClassOf 'Gene Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181093</classIRI>
<classLabel>Aquaporin-1</classLabel>
<newAxiom>'Aquaporin-1' SubClassOf 'Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein'</newAxiom>
<newAxiom>'Aquaporin-1' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain'</newAxiom>
<newAxiom>'Aquaporin-1' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane'</newAxiom>
<newAxiom>'Aquaporin-1' SubClassOf 'Transport Protein'</newAxiom>
<newAxiom>'Aquaporin-1' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'AQP1 Gene'</newAxiom>
<newAxiom>'Aquaporin-1' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Homeostatic Process'</newAxiom>
<newAxiom>'Aquaporin-1' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Transmembrane Transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181089</classIRI>
<classLabel>KIF18A wt Allele</classLabel>
<newAxiom>'KIF18A wt Allele' SubClassOf 'KIF18A Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181088</classIRI>
<classLabel>KIF18A Gene</classLabel>
<newAxiom>'KIF18A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'ATP Hydrolysis'</newAxiom>
<newAxiom>'KIF18A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Microtubule Depolymerization Process'</newAxiom>
<newAxiom>'KIF18A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Chromosome Segregation'</newAxiom>
<newAxiom>'KIF18A Gene' SubClassOf 'Transport Protein Gene'</newAxiom>
<newAxiom>'KIF18A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Metaphase Process'</newAxiom>
<newAxiom>'KIF18A Gene' SubClassOf 'Cell Cycle Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181087</classIRI>
<classLabel>SS18/SSX Rearrangement Positive</classLabel>
<newAxiom>'SS18/SSX Rearrangement Positive' SubClassOf 'Rearrangement Detected'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181086</classIRI>
<classLabel>D'Amico Prostate Cancer Risk Classification</classLabel>
<newAxiom>'D'Amico Prostate Cancer Risk Classification' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181085</classIRI>
<classLabel>University of California San Francisco Cancer of the Prostate Risk Assessment Score</classLabel>
<newAxiom>'University of California San Francisco Cancer of the Prostate Risk Assessment Score' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181084</classIRI>
<classLabel>National Comprehensive Cancer Network Prostate Cancer Risk Stratification for Clinically Localized Disease</classLabel>
<newAxiom>'National Comprehensive Cancer Network Prostate Cancer Risk Stratification for Clinically Localized Disease' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181083</classIRI>
<classLabel>Number of Peripancreatic Lymph Nodes Examined</classLabel>
<newAxiom>'Number of Peripancreatic Lymph Nodes Examined' SubClassOf 'Number of Lymph Nodes Examined'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181082</classIRI>
<classLabel>Iron Conjugated Polymers in Saline Suspension</classLabel>
<newAxiom>'Iron Conjugated Polymers in Saline Suspension' SubClassOf 'Contrast Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181092</classIRI>
<classLabel>AQP1 wt Allele</classLabel>
<newAxiom>'AQP1 wt Allele' SubClassOf 'AQP1 Gene'</newAxiom>
<newAxiom>'AQP1 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Proximal Tubule Bicarbonate Reclamation Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181091</classIRI>
<classLabel>AQP1 Gene</classLabel>
<newAxiom>'AQP1 Gene' SubClassOf 'Transport Protein Gene'</newAxiom>
<newAxiom>'AQP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transmembrane Transport'</newAxiom>
<newAxiom>'AQP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Homeostatic Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181090</classIRI>
<classLabel>Kinesin-Like Protein KIF18A</classLabel>
<newAxiom>'Kinesin-Like Protein KIF18A' EquivalentTo 'Transport Protein' and 'Cell Cycle Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Microtubule') and ('Gene_Product_Has_Associated_Anatomy' some 'Centrosome') and ('Gene_Product_Has_Biochemical_Function' some 'ATPase') and ('Gene_Product_Has_Biochemical_Function' some 'Microtubule Associated Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Metaphase Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Microtubule Depolymerization Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'ATP Hydrolysis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Chromosome Segregation') and ('Gene_Product_Encoded_By_Gene' some 'KIF18A Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181079</classIRI>
<classLabel>Hybrid Salivary Gland Carcinoma</classLabel>
<newAxiom>'Hybrid Salivary Gland Carcinoma' EquivalentTo 'Mixed Carcinoma' and 'Hybrid Salivary Gland Tumor' and 'Salivary Gland Carcinoma' and ('Disease_Excludes_Abnormal_Cell' some 'Malignant Squamous Cell')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181078</classIRI>
<classLabel>Hybrid Salivary Gland Tumor</classLabel>
<newAxiom>'Hybrid Salivary Gland Tumor' EquivalentTo 'Salivary Gland Neoplasm' and 'Mixed Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Salivary Gland') and ('Disease_Has_Finding' some 'Mixed Neoplastic Epithelial Cell Population') and ('Disease_Excludes_Abnormal_Cell' some 'Neoplastic Squamous Cell')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181077</classIRI>
<classLabel>Anti-GARP Monoclonal Antibody DS-1055a</classLabel>
<newAxiom>'Anti-GARP Monoclonal Antibody DS-1055a' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-GARP Monoclonal Antibody DS-1055a' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181076</classIRI>
<classLabel>Follicle-Stimulating Hormone</classLabel>
<newAxiom>'Follicle-Stimulating Hormone' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Intercellular Communication Process'</newAxiom>
<newAxiom>'Follicle-Stimulating Hormone' SubClassOf 'Gonadotropin'</newAxiom>
<newAxiom>'Follicle-Stimulating Hormone' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Gametogenesis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181075</classIRI>
<classLabel>SARS Coronavirus 2 AY.3</classLabel>
<newAxiom>'SARS Coronavirus 2 AY.3' SubClassOf 'SARS Coronavirus 2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181074</classIRI>
<classLabel>Age Data Obfuscated Indicator</classLabel>
<newAxiom>'Age Data Obfuscated Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181073</classIRI>
<classLabel>Number of Days Between Index Date and Treatment Start</classLabel>
<newAxiom>'Number of Days Between Index Date and Treatment Start' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181072</classIRI>
<classLabel>Number of Days Between Index Date and Treatment End</classLabel>
<newAxiom>'Number of Days Between Index Date and Treatment End' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181071</classIRI>
<classLabel>Number of Days Between Index Date and Specimen Collection</classLabel>
<newAxiom>'Number of Days Between Index Date and Specimen Collection' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181081</classIRI>
<classLabel>Early Stage Triple-Negative Breast Carcinoma</classLabel>
<newAxiom>'Early Stage Triple-Negative Breast Carcinoma' EquivalentTo 'Triple-Negative Breast Carcinoma' and 'Early Stage Breast Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181080</classIRI>
<classLabel>PDGFR alpha/KIT Mutant-specific Inhibitor NB003</classLabel>
<newAxiom>'PDGFR alpha/KIT Mutant-specific Inhibitor NB003' SubClassOf 'PDGFR Inhibitor'</newAxiom>
<newAxiom>'PDGFR alpha/KIT Mutant-specific Inhibitor NB003' SubClassOf 'c-KIT Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181069</classIRI>
<classLabel>Number of Days Between Index Date and Participation Consent</classLabel>
<newAxiom>'Number of Days Between Index Date and Participation Consent' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181068</classIRI>
<classLabel>Number of Days Between Index Date and Nucleotide Sequencing Assay</classLabel>
<newAxiom>'Number of Days Between Index Date and Nucleotide Sequencing Assay' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181067</classIRI>
<classLabel>Number of Days Between Index Date and Lost to Follow Up</classLabel>
<newAxiom>'Number of Days Between Index Date and Lost to Follow Up' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181066</classIRI>
<classLabel>Number of Days Between Index Date and Last Known Disease Status</classLabel>
<newAxiom>'Number of Days Between Index Date and Last Known Disease Status' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181065</classIRI>
<classLabel>Number of Days Between Index Date and Last Follow Up</classLabel>
<newAxiom>'Number of Days Between Index Date and Last Follow Up' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181064</classIRI>
<classLabel>Number of Days Between Index Date and Imaging Procedure</classLabel>
<newAxiom>'Number of Days Between Index Date and Imaging Procedure' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181063</classIRI>
<classLabel>Number of Days Between Index Date and Disease Progression</classLabel>
<newAxiom>'Number of Days Between Index Date and Disease Progression' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181062</classIRI>
<classLabel>Number of Days Between Index Date and Disease Recurrence</classLabel>
<newAxiom>'Number of Days Between Index Date and Disease Recurrence' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181061</classIRI>
<classLabel>Number of Days Between Index Date and Diagnosis</classLabel>
<newAxiom>'Number of Days Between Index Date and Diagnosis' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181060</classIRI>
<classLabel>Number of Days Between Index Date and Death</classLabel>
<newAxiom>'Number of Days Between Index Date and Death' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181070</classIRI>
<classLabel>Number of Days Between Index Date and Progression Free Status</classLabel>
<newAxiom>'Number of Days Between Index Date and Progression Free Status' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181059</classIRI>
<classLabel>Number of Days Between Index Date and Comorbidity</classLabel>
<newAxiom>'Number of Days Between Index Date and Comorbidity' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181057</classIRI>
<classLabel>Number of Days Between Index Date and Best Overall Response</classLabel>
<newAxiom>'Number of Days Between Index Date and Best Overall Response' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181056</classIRI>
<classLabel>Number of Days Between Index Date and Adverse Event</classLabel>
<newAxiom>'Number of Days Between Index Date and Adverse Event' SubClassOf 'Number of Elapsed Days'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181055</classIRI>
<classLabel>Selected Normal Whole Genome Sequencing Indicator</classLabel>
<newAxiom>'Selected Normal Whole Genome Sequencing Indicator' SubClassOf 'Selected Normal Sample Aliquot Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181054</classIRI>
<classLabel>Selected Normal Whole Exome Sequencing Indicator</classLabel>
<newAxiom>'Selected Normal Whole Exome Sequencing Indicator' SubClassOf 'Selected Normal Sample Aliquot Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181053</classIRI>
<classLabel>Selected Normal Targeted Sequencing Sample Aliquot Indicator</classLabel>
<newAxiom>'Selected Normal Targeted Sequencing Sample Aliquot Indicator' SubClassOf 'Selected Normal Sample Aliquot Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181052</classIRI>
<classLabel>Selected Normal Low Pass Whole Genome Sequencing Indicator</classLabel>
<newAxiom>'Selected Normal Low Pass Whole Genome Sequencing Indicator' SubClassOf 'Selected Normal Sample Aliquot Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181051</classIRI>
<classLabel>No Matched Normal Whole Genome Sequencing Indicator</classLabel>
<newAxiom>'No Matched Normal Whole Genome Sequencing Indicator' SubClassOf 'No Matched Normal Sequencing Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181050</classIRI>
<classLabel>No Matched Normal Whole Exome Sequencing Indicator</classLabel>
<newAxiom>'No Matched Normal Whole Exome Sequencing Indicator' SubClassOf 'No Matched Normal Sequencing Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181141</classIRI>
<classLabel>mRNA Cancer Vaccine</classLabel>
<newAxiom>'mRNA Cancer Vaccine' SubClassOf 'Antineoplastic Vaccine'</newAxiom>
<newAxiom>'mRNA Cancer Vaccine' SubClassOf 'mRNA Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181140</classIRI>
<classLabel>mRNA COVID-19 Vaccine</classLabel>
<newAxiom>'mRNA COVID-19 Vaccine' SubClassOf 'COVID-19 Vaccine'</newAxiom>
<newAxiom>'mRNA COVID-19 Vaccine' SubClassOf 'mRNA Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181139</classIRI>
<classLabel>Soluble CD40 Ligand Measurement</classLabel>
<newAxiom>'Soluble CD40 Ligand Measurement' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181138</classIRI>
<classLabel>Soluble CD40 Measurement</classLabel>
<newAxiom>'Soluble CD40 Measurement' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181137</classIRI>
<classLabel>NTRK3 Fusion Negative</classLabel>
<newAxiom>'NTRK3 Fusion Negative' SubClassOf 'TRK Receptor Family Fusion Negative'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181136</classIRI>
<classLabel>NTRK2 Fusion Negative</classLabel>
<newAxiom>'NTRK2 Fusion Negative' SubClassOf 'TRK Receptor Family Fusion Negative'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181135</classIRI>
<classLabel>NTRK1 Fusion Negative</classLabel>
<newAxiom>'NTRK1 Fusion Negative' SubClassOf 'TRK Receptor Family Fusion Negative'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181134</classIRI>
<classLabel>Transbronchial Cryobiopsy Guided by Three-Dimensional Fluoroscopy</classLabel>
<newAxiom>'Transbronchial Cryobiopsy Guided by Three-Dimensional Fluoroscopy' SubClassOf 'Image Guided Biopsy'</newAxiom>
<newAxiom>'Transbronchial Cryobiopsy Guided by Three-Dimensional Fluoroscopy' SubClassOf 'Transbronchial Lung Biopsy'</newAxiom>
<newAxiom>'Transbronchial Cryobiopsy Guided by Three-Dimensional Fluoroscopy' SubClassOf 'Cryobiopsy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181133</classIRI>
<classLabel>Cryobiopsy</classLabel>
<newAxiom>'Cryobiopsy' SubClassOf 'Endoscopic Biopsy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181132</classIRI>
<classLabel>Lymphocyte Antigen 96</classLabel>
<newAxiom>'Lymphocyte Antigen 96' EquivalentTo 'Immunoprotein' and ('Gene_Product_Is_Element_In_Pathway' some 'Toll-Like Receptor Signaling Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Receptor Signaling') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Antibacterial Response') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Defense Process') and ('Gene_Product_Encoded_By_Gene' some 'LY96 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181131</classIRI>
<classLabel>LY96 wt Allele</classLabel>
<newAxiom>'LY96 wt Allele' SubClassOf 'LY96 Gene'</newAxiom>
<newAxiom>'LY96 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Toll-Like Receptor Signaling Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181130</classIRI>
<classLabel>LY96 Gene</classLabel>
<newAxiom>'LY96 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell Defense Process'</newAxiom>
<newAxiom>'LY96 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Antibacterial Response'</newAxiom>
<newAxiom>'LY96 Gene' SubClassOf 'Immunoprotein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181129</classIRI>
<classLabel>p53-Induced Death Domain-Containing Protein 1</classLabel>
<newAxiom>'p53-Induced Death Domain-Containing Protein 1' EquivalentTo 'Serine Protease' and ('Gene_Product_Is_Element_In_Pathway' some 'Apoptosis Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'p53 Signaling Pathway KEGG') and ('Gene_Product_Is_Element_In_Pathway' some 'Caspase Cascade in Apoptosis') and ('Gene_Product_Is_Element_In_Pathway' some 'p53 Effector Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleus') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoplasm') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Death Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Leucine-Rich Repeat') and ('Gene_Product_Has_Biochemical_Function' some 'Endopeptidase') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Proteolysis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Positive Regulation of Apoptosis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Death Signaling Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Caspase Activation') and ('Gene_Product_Encoded_By_Gene' some 'PIDD1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181128</classIRI>
<classLabel>PIDD1 wt Allele</classLabel>
<newAxiom>'PIDD1 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Apoptosis Pathway'</newAxiom>
<newAxiom>'PIDD1 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Caspase Cascade in Apoptosis'</newAxiom>
<newAxiom>'PIDD1 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'p53 Effector Pathway'</newAxiom>
<newAxiom>'PIDD1 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'p53 Signaling Pathway KEGG'</newAxiom>
<newAxiom>'PIDD1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '11p15.5'</newAxiom>
<newAxiom>'PIDD1 wt Allele' SubClassOf 'PIDD1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181127</classIRI>
<classLabel>PIDD1 Gene</classLabel>
<newAxiom>'PIDD1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell Death Signaling Process'</newAxiom>
<newAxiom>'PIDD1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Positive Regulation of Apoptosis'</newAxiom>
<newAxiom>'PIDD1 Gene' SubClassOf 'Peptidase Gene'</newAxiom>
<newAxiom>'PIDD1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Caspase Activation'</newAxiom>
<newAxiom>'PIDD1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Proteolysis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181126</classIRI>
<classLabel>Cytochrome C Oxidase Subunit 6A2, Mitochondrial</classLabel>
<newAxiom>'Cytochrome C Oxidase Subunit 6A2, Mitochondrial' EquivalentTo 'Regulatory Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Alzheimer's Disease Pathway KEGG') and ('Gene_Product_Is_Element_In_Pathway' some 'Amyotrophic Lateral Sclerosis Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Huntington's Disease Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Oxidative Phosphorylation Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Parkinson's Disease Pathway KEGG') and ('Gene_Product_Is_Element_In_Pathway' some 'Prion Disease Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Cardiac Muscle Contraction Pathway') and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Chemical_Classification' some 'Mitochondrial Membrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Mitochondrion') and ('Gene_Product_Has_Associated_Anatomy' some 'Inner Mitochondrial Membrane') and ('Gene_Product_Has_Associated_Anatomy' some 'Electron-Transport Chain of the Respiratory Enzymes') and ('Gene_Product_Expressed_In_Tissue' some 'All Sites') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Is_Physical_Part_Of' some 'Cytochrome C Oxidase') and ('Gene_Product_Has_Biochemical_Function' some 'Protein Complex Subunit') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Energy Metabolism Process') and ('Gene_Product_Encoded_By_Gene' some 'COX6A2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181125</classIRI>
<classLabel>COX6A2 wt Allele</classLabel>
<newAxiom>'COX6A2 wt Allele' EquivalentTo 'COX6A2 Gene' and ('Gene_Is_Element_In_Pathway' some 'Alzheimer's Disease Pathway KEGG') and ('Gene_Is_Element_In_Pathway' some 'Amyotrophic Lateral Sclerosis Pathway') and ('Gene_Is_Element_In_Pathway' some 'Huntington's Disease Pathway') and ('Gene_Is_Element_In_Pathway' some 'Oxidative Phosphorylation Pathway') and ('Gene_Is_Element_In_Pathway' some 'Parkinson's Disease Pathway KEGG') and ('Gene_Is_Element_In_Pathway' some 'Prion Disease Pathway') and ('Gene_Is_Element_In_Pathway' some 'Cardiac Muscle Contraction Pathway') and ('Gene_In_Chromosomal_Location' some '16p11.2')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181124</classIRI>
<classLabel>COX6A2 Gene</classLabel>
<newAxiom>'COX6A2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Energy Metabolism Process'</newAxiom>
<newAxiom>'COX6A2 Gene' SubClassOf 'Oxidoreductase Gene'</newAxiom>
<newAxiom>'COX6A2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Oxidation/Reduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181123</classIRI>
<classLabel>Clathrin Coat Assembly Protein AP180</classLabel>
<newAxiom>'Clathrin Coat Assembly Protein AP180' EquivalentTo 'Structural Protein' and ('Gene_Product_Has_Chemical_Classification' some 'Membrane Protein') and ('Gene_Product_Has_Chemical_Classification' some 'Phosphoprotein') and ('Gene_Product_Has_Associated_Anatomy' some 'Coated Pit') and ('Gene_Product_Has_Biochemical_Function' some 'Scaffolding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Endocytotic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Protein Interaction') and ('Gene_Product_Encoded_By_Gene' some 'SNAP91 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181122</classIRI>
<classLabel>SNAP91 wt Allele</classLabel>
<newAxiom>'SNAP91 wt Allele' SubClassOf 'SNAP91 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181121</classIRI>
<classLabel>SNAP91 Gene</classLabel>
<newAxiom>'SNAP91 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Endocytotic Process'</newAxiom>
<newAxiom>'SNAP91 Gene' SubClassOf 'Structural Protein Gene'</newAxiom>
<newAxiom>'SNAP91 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein-Protein Interaction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181120</classIRI>
<classLabel>F-BAR Domain Only Protein 1</classLabel>
<newAxiom>'F-BAR Domain Only Protein 1' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Coated Pit'</newAxiom>
<newAxiom>'F-BAR Domain Only Protein 1' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Endocytotic Process'</newAxiom>
<newAxiom>'F-BAR Domain Only Protein 1' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Regulation of Cell Shape'</newAxiom>
<newAxiom>'F-BAR Domain Only Protein 1' SubClassOf 'Structural Protein'</newAxiom>
<newAxiom>'F-BAR Domain Only Protein 1' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'FCHO1 Gene'</newAxiom>
<newAxiom>'F-BAR Domain Only Protein 1' SubClassOf 'Gene_Product_Has_Chemical_Classification' some 'Membrane Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181119</classIRI>
<classLabel>FCHO1 wt Allele</classLabel>
<newAxiom>'FCHO1 wt Allele' SubClassOf 'FCHO1 Gene'</newAxiom>
<newAxiom>'FCHO1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '19p13.11'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181118</classIRI>
<classLabel>FCHO1 Gene</classLabel>
<newAxiom>'FCHO1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Endocytotic Process'</newAxiom>
<newAxiom>'FCHO1 Gene' SubClassOf 'Structural Protein Gene'</newAxiom>
<newAxiom>'FCHO1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Regulation of Cell Shape'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181117</classIRI>
<classLabel>E3 Ubiquitin-Protein Ligase Pellino Homolog 3</classLabel>
<newAxiom>'E3 Ubiquitin-Protein Ligase Pellino Homolog 3' EquivalentTo 'E3 Ubiquitin-Protein Transferase' and ('Gene_Product_Has_Associated_Anatomy' some 'Cytosol') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Ring Finger Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Receptor Signaling') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Polyubiquitination') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Interleukin Signaling Process') and ('Gene_Product_Encoded_By_Gene' some 'PELI3 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181116</classIRI>
<classLabel>PELI3 wt Allele</classLabel>
<newAxiom>'PELI3 wt Allele' SubClassOf 'PELI3 Gene'</newAxiom>
<newAxiom>'PELI3 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '11q13.2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181115</classIRI>
<classLabel>PELI3 Gene</classLabel>
<newAxiom>'PELI3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Polyubiquitination'</newAxiom>
<newAxiom>'PELI3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Receptor Signaling'</newAxiom>
<newAxiom>'PELI3 Gene' SubClassOf 'Ubiquitin-Transferase Gene'</newAxiom>
<newAxiom>'PELI3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Interleukin Signaling Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181114</classIRI>
<classLabel>Anti-BCMA/CD3 Bispecific Monoclonal Antibody</classLabel>
<newAxiom>'Anti-BCMA/CD3 Bispecific Monoclonal Antibody' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-BCMA/CD3 Bispecific Monoclonal Antibody' SubClassOf 'Anti-BCMA Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181113</classIRI>
<classLabel>Anti-BCMA Monoclonal Antibody</classLabel>
<newAxiom>'Anti-BCMA Monoclonal Antibody' SubClassOf 'BCMA-targeting Agent'</newAxiom>
<newAxiom>'Anti-BCMA Monoclonal Antibody' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-BCMA Monoclonal Antibody' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181112</classIRI>
<classLabel>60 kDa SS-A/Ro Ribonucleoprotein</classLabel>
<newAxiom>'60 kDa SS-A/Ro Ribonucleoprotein' EquivalentTo 'RNA Binding Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Systemic Lupus Erythematosus Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoplasm') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'RNA Recognition Motif') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Interferon Signaling Process') and ('Gene_Product_Encoded_By_Gene' some 'RO60 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181111</classIRI>
<classLabel>BCMA-targeting Agent</classLabel>
<newAxiom>'BCMA-targeting Agent' SubClassOf 'Targeted Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181110</classIRI>
<classLabel>RO60 wt Allele</classLabel>
<newAxiom>'RO60 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Systemic Lupus Erythematosus Pathway'</newAxiom>
<newAxiom>'RO60 wt Allele' SubClassOf 'RO60 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181108</classIRI>
<classLabel>Anti-BCMA Antibody-drug Conjugate</classLabel>
<newAxiom>'Anti-BCMA Antibody-drug Conjugate' SubClassOf 'BCMA-targeting Agent'</newAxiom>
<newAxiom>'Anti-BCMA Antibody-drug Conjugate' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181107</classIRI>
<classLabel>Polyadenylate-Binding Protein-Interacting Protein 1</classLabel>
<newAxiom>'Polyadenylate-Binding Protein-Interacting Protein 1' EquivalentTo 'Translation Process Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoplasm') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'RNA-Protein Interaction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Translational Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Translation Initiation') and ('Gene_Product_Encoded_By_Gene' some 'PAIP1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181106</classIRI>
<classLabel>PAIP1 wt Allele</classLabel>
<newAxiom>'PAIP1 wt Allele' SubClassOf 'PAIP1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181105</classIRI>
<classLabel>PAIP1 Gene</classLabel>
<newAxiom>'PAIP1 Gene' SubClassOf 'Translation Process Gene'</newAxiom>
<newAxiom>'PAIP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Translational Activation'</newAxiom>
<newAxiom>'PAIP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Translation Initiation'</newAxiom>
<newAxiom>'PAIP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA-Protein Interaction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181104</classIRI>
<classLabel>Bispecific Antibody JNJ-70218902</classLabel>
<newAxiom>'Bispecific Antibody JNJ-70218902' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
<newAxiom>'Bispecific Antibody JNJ-70218902' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181103</classIRI>
<classLabel>Persephin</classLabel>
<newAxiom>'Persephin' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'PSPN Gene'</newAxiom>
<newAxiom>'Persephin' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Nerve Cell Survival'</newAxiom>
<newAxiom>'Persephin' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space'</newAxiom>
<newAxiom>'Persephin' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Nervous System Development'</newAxiom>
<newAxiom>'Persephin' SubClassOf 'Neurotrophic Factor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181102</classIRI>
<classLabel>PSPN wt Allele</classLabel>
<newAxiom>'PSPN wt Allele' SubClassOf 'PSPN Gene'</newAxiom>
<newAxiom>'PSPN wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '19p13.3'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181101</classIRI>
<classLabel>PSPN Gene</classLabel>
<newAxiom>'PSPN Gene' SubClassOf 'Growth Factor Gene'</newAxiom>
<newAxiom>'PSPN Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Nervous System Development'</newAxiom>
<newAxiom>'PSPN Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Nerve Cell Survival'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181100</classIRI>
<classLabel>METTL14 wt Allele</classLabel>
<newAxiom>'METTL14 wt Allele' SubClassOf 'METTL14 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181109</classIRI>
<classLabel>RO60 Gene</classLabel>
<newAxiom>'RO60 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Binding'</newAxiom>
<newAxiom>'RO60 Gene' SubClassOf 'Ligand Binding Protein Gene'</newAxiom>
<newAxiom>'RO60 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Interferon Signaling Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180899</classIRI>
<classLabel>T1b3 Stage Finding</classLabel>
<newAxiom>'T1b3 Stage Finding' SubClassOf 'T1b Stage Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180898</classIRI>
<classLabel>Dynamic Contrast-enhanced MR Perfusion</classLabel>
<newAxiom>'Dynamic Contrast-enhanced MR Perfusion' SubClassOf 'Perfusion Magnetic Resonance Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180897</classIRI>
<classLabel>Refractory Acute Myeloid Leukemia with Myelodysplasia-Related Changes</classLabel>
<newAxiom>'Refractory Acute Myeloid Leukemia with Myelodysplasia-Related Changes' EquivalentTo 'Refractory Acute Myeloid Leukemia' and 'Acute Myeloid Leukemia with Myelodysplasia-Related Changes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180896</classIRI>
<classLabel>Advanced Mucosal Melanoma</classLabel>
<newAxiom>'Advanced Mucosal Melanoma' EquivalentTo 'Metastatic Mucosal Melanoma' and 'Advanced Non-Cutaneous Melanoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180895</classIRI>
<classLabel>Advanced Non-Cutaneous Melanoma</classLabel>
<newAxiom>'Advanced Non-Cutaneous Melanoma' EquivalentTo 'Advanced Melanoma' and 'Metastatic Non-Cutaneous Melanoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180894</classIRI>
<classLabel>Refractory Mucosal Melanoma</classLabel>
<newAxiom>'Refractory Mucosal Melanoma' EquivalentTo 'Mucosal Melanoma' and 'Refractory Non-Cutaneous Melanoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180893</classIRI>
<classLabel>Recurrent Medulloblastoma, WNT-Activated</classLabel>
<newAxiom>'Recurrent Medulloblastoma, WNT-Activated' EquivalentTo 'Medulloblastoma, WNT-Activated' and 'Recurrent Medulloblastoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180892</classIRI>
<classLabel>Refractory Medulloblastoma, WNT-Activated</classLabel>
<newAxiom>'Refractory Medulloblastoma, WNT-Activated' EquivalentTo 'Medulloblastoma, WNT-Activated' and 'Refractory Medulloblastoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180891</classIRI>
<classLabel>Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck</classLabel>
<newAxiom>'Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck' EquivalentTo 'Locally Advanced Skin Squamous Cell Carcinoma' and 'Locally Advanced Head and Neck Squamous Cell Carcinoma' and 'Metastatic Cutaneous Squamous Cell Carcinoma of the Head and Neck'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180890</classIRI>
<classLabel>Imaging Finding Ranges</classLabel>
<newAxiom>'Imaging Finding Ranges' SubClassOf 'Imaging Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180888</classIRI>
<classLabel>Adult Myofibroma</classLabel>
<newAxiom>'Adult Myofibroma' EquivalentTo 'Myofibroma' and ('Disease_Has_Finding' some 'Adulthood Lesion')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180887</classIRI>
<classLabel>Infantile Myofibroma</classLabel>
<newAxiom>'Infantile Myofibroma' EquivalentTo 'Myofibroma' and ('Disease_Has_Finding' some 'Infantile Lesion')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180886</classIRI>
<classLabel>International Diffuse Intrinsic Pontine Glioma Registry Case Report Form Questionnaire</classLabel>
<newAxiom>'International Diffuse Intrinsic Pontine Glioma Registry Case Report Form Questionnaire' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180889</classIRI>
<classLabel>Anti-CD226 Agonist Antibody LY3435151</classLabel>
<newAxiom>'Anti-CD226 Agonist Antibody LY3435151' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180998</classIRI>
<classLabel>Cranial Nerve XI Palsy</classLabel>
<newAxiom>'Cranial Nerve XI Palsy' SubClassOf 'Cranial Nerve Palsy'</newAxiom>
<newAxiom>'Cranial Nerve XI Palsy' SubClassOf 'Accessory Nerve Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180997</classIRI>
<classLabel>Cranial Nerve X Palsy</classLabel>
<newAxiom>'Cranial Nerve X Palsy' SubClassOf 'Vagus Nerve Disorder'</newAxiom>
<newAxiom>'Cranial Nerve X Palsy' SubClassOf 'Cranial Nerve Palsy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180996</classIRI>
<classLabel>Cranial Nerve VIII Palsy</classLabel>
<newAxiom>'Cranial Nerve VIII Palsy' SubClassOf 'Cranial Nerve Palsy'</newAxiom>
<newAxiom>'Cranial Nerve VIII Palsy' SubClassOf 'Vestibulocochlear Nerve Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180995</classIRI>
<classLabel>Cranial Nerve V Palsy</classLabel>
<newAxiom>'Cranial Nerve V Palsy' SubClassOf 'Non-Neoplastic Trigeminal Nerve Disorder'</newAxiom>
<newAxiom>'Cranial Nerve V Palsy' SubClassOf 'Cranial Nerve Palsy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180994</classIRI>
<classLabel>Cranial Nerve IV Palsy</classLabel>
<newAxiom>'Cranial Nerve IV Palsy' SubClassOf 'Trochlear Nerve Disorder'</newAxiom>
<newAxiom>'Cranial Nerve IV Palsy' SubClassOf 'Cranial Nerve Palsy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180993</classIRI>
<classLabel>F-18 DCFPyL PSMA Positron Emission Tomography</classLabel>
<newAxiom>'F-18 DCFPyL PSMA Positron Emission Tomography' SubClassOf 'F-18 Sodium Fluoride Positron Emission Tomography'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180992</classIRI>
<classLabel>Cranial Nerve II Palsy</classLabel>
<newAxiom>'Cranial Nerve II Palsy' SubClassOf 'Cranial Nerve Palsy'</newAxiom>
<newAxiom>'Cranial Nerve II Palsy' SubClassOf 'Non-Neoplastic Optic Nerve Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180991</classIRI>
<classLabel>Sapiosexuality</classLabel>
<newAxiom>'Sapiosexuality' SubClassOf 'Sexual Orientation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180990</classIRI>
<classLabel>Omnisexuality</classLabel>
<newAxiom>'Omnisexuality' SubClassOf 'Sexual Orientation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180999</classIRI>
<classLabel>Cranial Nerve XII Palsy</classLabel>
<newAxiom>'Cranial Nerve XII Palsy' SubClassOf 'Cranial Nerve Palsy'</newAxiom>
<newAxiom>'Cranial Nerve XII Palsy' SubClassOf 'Hypoglossal Nerve Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180987</classIRI>
<classLabel>Bacillus Calmette-Guerin Substrain Danish 1331 Live Antigen</classLabel>
<newAxiom>'Bacillus Calmette-Guerin Substrain Danish 1331 Live Antigen' SubClassOf 'Bacillus Calmette-Guerin Antigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180986</classIRI>
<classLabel>Refractory T-Cell Large Granular Lymphocyte Leukemia</classLabel>
<newAxiom>'Refractory T-Cell Large Granular Lymphocyte Leukemia' EquivalentTo 'Refractory Chronic Leukemia' and 'Refractory Mature T-Cell and NK-Cell Neoplasm' and 'T-Cell Large Granular Lymphocyte Leukemia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180985</classIRI>
<classLabel>Recurrent T-Cell Large Granular Lymphocyte Leukemia</classLabel>
<newAxiom>'Recurrent T-Cell Large Granular Lymphocyte Leukemia' EquivalentTo 'Recurrent Chronic Leukemia' and 'Recurrent Mature T-Cell and NK-Cell Neoplasm' and 'T-Cell Large Granular Lymphocyte Leukemia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180984</classIRI>
<classLabel>TRA-2-39 Antigen</classLabel>
<newAxiom>'TRA-2-39 Antigen' SubClassOf 'Tumor Antigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180983</classIRI>
<classLabel>TRA-1-80 Antigen</classLabel>
<newAxiom>'TRA-1-80 Antigen' SubClassOf 'Tumor Antigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180982</classIRI>
<classLabel>SSEA-5 Antigen</classLabel>
<newAxiom>'SSEA-5 Antigen' SubClassOf 'Ganglioside'</newAxiom>
<newAxiom>'SSEA-5 Antigen' SubClassOf 'Tumor Antigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180981</classIRI>
<classLabel>SSEA-3 Antigen</classLabel>
<newAxiom>'SSEA-3 Antigen' SubClassOf 'Tumor Antigen'</newAxiom>
<newAxiom>'SSEA-3 Antigen' SubClassOf 'Ganglioside'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180980</classIRI>
<classLabel>Recurrent Clear Cell Sarcoma of Soft Tissue</classLabel>
<newAxiom>'Recurrent Clear Cell Sarcoma of Soft Tissue' EquivalentTo 'Recurrent Soft Tissue Sarcoma' and 'Clear Cell Sarcoma of Soft Tissue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180989</classIRI>
<classLabel>Polysexuality</classLabel>
<newAxiom>'Polysexuality' SubClassOf 'Sexual Orientation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180988</classIRI>
<classLabel>Two-spirit</classLabel>
<newAxiom>'Two-spirit' SubClassOf 'Gender'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180976</classIRI>
<classLabel>EWSR1/WT1 Fusion Positive</classLabel>
<newAxiom>'EWSR1/WT1 Fusion Positive' SubClassOf 'Rearrangement Detected'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180975</classIRI>
<classLabel>Tumor Mutation Burden Greater than or Equal to 10 Mutations per Megabase</classLabel>
<newAxiom>'Tumor Mutation Burden Greater than or Equal to 10 Mutations per Megabase' SubClassOf 'High Tumor Mutation Burden'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180974</classIRI>
<classLabel>Deleterious RECQL Gene Mutation</classLabel>
<newAxiom>'Deleterious RECQL Gene Mutation' SubClassOf 'RECQL Gene Mutation'</newAxiom>
<newAxiom>'Deleterious RECQL Gene Mutation' SubClassOf 'Deleterious Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180973</classIRI>
<classLabel>RECQL Gene Mutation</classLabel>
<newAxiom>'RECQL Gene Mutation' SubClassOf 'Gene Variant'</newAxiom>
<newAxiom>'RECQL Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'RECQL Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180972</classIRI>
<classLabel>BRD9 Degrader FHD-609</classLabel>
<newAxiom>'BRD9 Degrader FHD-609' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180971</classIRI>
<classLabel>Simulated Forest Immersion Therapy</classLabel>
<newAxiom>'Simulated Forest Immersion Therapy' SubClassOf 'Therapeutic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180970</classIRI>
<classLabel>EGFR NP_005219.2:p.S768X</classLabel>
<newAxiom>'EGFR NP_005219.2:p.S768X' SubClassOf 'EGFR Protein Variant'</newAxiom>
<newAxiom>'EGFR NP_005219.2:p.S768X' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'EGFR Exon 20 Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180979</classIRI>
<classLabel>Refractory Clear Cell Sarcoma of Soft Tissue</classLabel>
<newAxiom>'Refractory Clear Cell Sarcoma of Soft Tissue' EquivalentTo 'Refractory Soft Tissue Sarcoma' and 'Clear Cell Sarcoma of Soft Tissue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180978</classIRI>
<classLabel>Very High Risk</classLabel>
<newAxiom>'Very High Risk' SubClassOf 'Risk'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180977</classIRI>
<classLabel>SARS Coronavirus 2 AY.1</classLabel>
<newAxiom>'SARS Coronavirus 2 AY.1' SubClassOf 'SARS Coronavirus 2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180965</classIRI>
<classLabel>Cervical Cancer Pathologic Primary Tumor TNM Finding v9</classLabel>
<newAxiom>'Cervical Cancer Pathologic Primary Tumor TNM Finding v9' SubClassOf 'Cervical Cancer Pathologic TNM Finding v9'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180964</classIRI>
<classLabel>Cervical Cancer pM1 TNM Finding v9</classLabel>
<newAxiom>'Cervical Cancer pM1 TNM Finding v9' SubClassOf 'Cervical Cancer Pathologic Distant Metastasis TNM Finding v9'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180963</classIRI>
<classLabel>Activating EGFR Exon 21 Mutation</classLabel>
<newAxiom>'Activating EGFR Exon 21 Mutation' SubClassOf 'EGFR Activating Mutation'</newAxiom>
<newAxiom>'Activating EGFR Exon 21 Mutation' SubClassOf 'EGFR Exon 21 Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180962</classIRI>
<classLabel>Cervical Cancer cM1 TNM Finding v9</classLabel>
<newAxiom>'Cervical Cancer cM1 TNM Finding v9' SubClassOf 'Cervical Cancer Clinical Distant Metastasis TNM Finding v9'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180961</classIRI>
<classLabel>Cervical Cancer cM0 TNM Finding v9</classLabel>
<newAxiom>'Cervical Cancer cM0 TNM Finding v9' SubClassOf 'Cervical Cancer Clinical Distant Metastasis TNM Finding v9'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180960</classIRI>
<classLabel>Cervical Cancer Pathologic Distant Metastasis TNM Finding v9</classLabel>
<newAxiom>'Cervical Cancer Pathologic Distant Metastasis TNM Finding v9' SubClassOf 'Cervical Cancer Pathologic TNM Finding v9'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180969</classIRI>
<classLabel>Fatty Acyl</classLabel>
<newAxiom>'Fatty Acyl' SubClassOf 'Lipid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180968</classIRI>
<classLabel>Polyketide</classLabel>
<newAxiom>'Polyketide' SubClassOf 'Lipid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180967</classIRI>
<classLabel>EGFR NP_005219.2:p.L861X</classLabel>
<newAxiom>'EGFR NP_005219.2:p.L861X' SubClassOf 'EGFR Protein Variant'</newAxiom>
<newAxiom>'EGFR NP_005219.2:p.L861X' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'EGFR Exon 21 Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180966</classIRI>
<classLabel>Prenol Lipid</classLabel>
<newAxiom>'Prenol Lipid' SubClassOf 'Lipid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180954</classIRI>
<classLabel>Female Reproductive System Cancer TNM Finding v9</classLabel>
<newAxiom>'Female Reproductive System Cancer TNM Finding v9' SubClassOf 'Cancer TNM Finding by Site'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180953</classIRI>
<classLabel>Activating EGFR Exon 20 Mutation</classLabel>
<newAxiom>'Activating EGFR Exon 20 Mutation' SubClassOf 'EGFR Exon 20 Mutation'</newAxiom>
<newAxiom>'Activating EGFR Exon 20 Mutation' SubClassOf 'EGFR Activating Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180952</classIRI>
<classLabel>Activating EGFR Exon 19 Mutation</classLabel>
<newAxiom>'Activating EGFR Exon 19 Mutation' SubClassOf 'EGFR Exon 19 Mutation'</newAxiom>
<newAxiom>'Activating EGFR Exon 19 Mutation' SubClassOf 'EGFR Activating Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180951</classIRI>
<classLabel>Activating EGFR Exon 18 Mutation</classLabel>
<newAxiom>'Activating EGFR Exon 18 Mutation' SubClassOf 'EGFR Activating Mutation'</newAxiom>
<newAxiom>'Activating EGFR Exon 18 Mutation' SubClassOf 'EGFR Exon 18 Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180950</classIRI>
<classLabel>ROS1 Gene Alteration Negative</classLabel>
<newAxiom>'ROS1 Gene Alteration Negative' SubClassOf 'Negative Test Result'</newAxiom>
<newAxiom>'ROS1 Gene Alteration Negative' SubClassOf 'Genetic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180959</classIRI>
<classLabel>Cervical Cancer Clinical Distant Metastasis TNM Finding v9</classLabel>
<newAxiom>'Cervical Cancer Clinical Distant Metastasis TNM Finding v9' SubClassOf 'Cervical Cancer Clinical TNM Finding v9'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180958</classIRI>
<classLabel>Cervical Cancer Pathologic TNM Finding v9</classLabel>
<newAxiom>'Cervical Cancer Pathologic TNM Finding v9' SubClassOf 'Cervical Cancer TNM Finding v9'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180957</classIRI>
<classLabel>Spiked-in Standard</classLabel>
<newAxiom>'Spiked-in Standard' SubClassOf 'Scientific Control'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180956</classIRI>
<classLabel>Cervical Cancer Clinical TNM Finding v9</classLabel>
<newAxiom>'Cervical Cancer Clinical TNM Finding v9' SubClassOf 'Cervical Cancer TNM Finding v9'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180955</classIRI>
<classLabel>Cervical Cancer TNM Finding v9</classLabel>
<newAxiom>'Cervical Cancer TNM Finding v9' SubClassOf 'Female Reproductive System Cancer TNM Finding v9'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180943</classIRI>
<classLabel>Human Papillomavirus-Related Vaginal Adenocarcinoma</classLabel>
<newAxiom>'Human Papillomavirus-Related Vaginal Adenocarcinoma' EquivalentTo 'Human Papillomavirus-Related Adenocarcinoma' and 'Vaginal Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180942</classIRI>
<classLabel>Chromosome 9 Abnormality</classLabel>
<newAxiom>'Chromosome 9 Abnormality' SubClassOf 'Cytogenetic Abnormality'</newAxiom>
<newAxiom>'Chromosome 9 Abnormality' SubClassOf 'Cytogenetic_Abnormality_Involves_Chromosome' some 'Chromosome 9'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180941</classIRI>
<classLabel>Monoallelic RB1 Gene Mutation</classLabel>
<newAxiom>'Monoallelic RB1 Gene Mutation' SubClassOf 'Monoallelic Mutation'</newAxiom>
<newAxiom>'Monoallelic RB1 Gene Mutation' SubClassOf 'RB1 Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180940</classIRI>
<classLabel>Biallelic RB1 Gene Mutation</classLabel>
<newAxiom>'Biallelic RB1 Gene Mutation' SubClassOf 'Biallelic Mutation'</newAxiom>
<newAxiom>'Biallelic RB1 Gene Mutation' SubClassOf 'RB1 Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180949</classIRI>
<classLabel>NTRK Family Gene Alteration Negative</classLabel>
<newAxiom>'NTRK Family Gene Alteration Negative' SubClassOf 'Negative Test Result'</newAxiom>
<newAxiom>'NTRK Family Gene Alteration Negative' SubClassOf 'Genetic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180948</classIRI>
<classLabel>Urethral Adenocarcinoma of Skene Gland Origin</classLabel>
<newAxiom>'Urethral Adenocarcinoma of Skene Gland Origin' EquivalentTo 'Adenocarcinoma of Skene Gland Origin' and 'Accessory Urethral Gland Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180947</classIRI>
<classLabel>Vaginal Adenocarcinoma of Skene Gland Origin</classLabel>
<newAxiom>'Vaginal Adenocarcinoma of Skene Gland Origin' EquivalentTo 'Adenocarcinoma of Skene Gland Origin' and 'Vaginal Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180946</classIRI>
<classLabel>Vaginal Mucinous Adenocarcinoma, Intestinal-Type</classLabel>
<newAxiom>'Vaginal Mucinous Adenocarcinoma, Intestinal-Type' EquivalentTo 'Vaginal Mucinous Adenocarcinoma' and 'Intestinal-Type Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180945</classIRI>
<classLabel>Vaginal Mucinous Adenocarcinoma, Gastric-Type</classLabel>
<newAxiom>'Vaginal Mucinous Adenocarcinoma, Gastric-Type' EquivalentTo 'Vaginal Mucinous Adenocarcinoma' and ('Disease_Has_Finding' some 'Gastric-Type Epithelial Differentiation')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180944</classIRI>
<classLabel>BRAF Gene Alteration Negative</classLabel>
<newAxiom>'BRAF Gene Alteration Negative' SubClassOf 'Negative Test Result'</newAxiom>
<newAxiom>'BRAF Gene Alteration Negative' SubClassOf 'Genetic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180932</classIRI>
<classLabel>Circulating Neutrophil Extracellular Trap Measurement</classLabel>
<newAxiom>'Circulating Neutrophil Extracellular Trap Measurement' SubClassOf 'Immunology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180931</classIRI>
<classLabel>Neutrophil Extracellular Trap</classLabel>
<newAxiom>'Neutrophil Extracellular Trap' SubClassOf 'Extracellular Structure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180930</classIRI>
<classLabel>NPM1 Gene Alteration Positive</classLabel>
<newAxiom>'NPM1 Gene Alteration Positive' SubClassOf 'Positive Laboratory Test Result'</newAxiom>
<newAxiom>'NPM1 Gene Alteration Positive' SubClassOf 'Genetic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180939</classIRI>
<classLabel>Non-Synonymous KRAS Gene Mutation</classLabel>
<newAxiom>'Non-Synonymous KRAS Gene Mutation' SubClassOf 'KRAS Gene Mutation'</newAxiom>
<newAxiom>'Non-Synonymous KRAS Gene Mutation' SubClassOf 'Non-synonymous RAS Family Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180938</classIRI>
<classLabel>MYBL1 Gene Rearrangement</classLabel>
<newAxiom>'MYBL1 Gene Rearrangement' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'MYBL1 Gene'</newAxiom>
<newAxiom>'MYBL1 Gene Rearrangement' SubClassOf 'Cytogenetic_Abnormality_Involves_Chromosome' some 'Chromosome 8'</newAxiom>
<newAxiom>'MYBL1 Gene Rearrangement' SubClassOf 'Gene Rearrangement Abnormality'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180937</classIRI>
<classLabel>MYB Gene Rearrangement</classLabel>
<newAxiom>'MYB Gene Rearrangement' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'MYB Gene'</newAxiom>
<newAxiom>'MYB Gene Rearrangement' SubClassOf 'Cytogenetic_Abnormality_Involves_Chromosome' some 'Chromosome 6'</newAxiom>
<newAxiom>'MYB Gene Rearrangement' SubClassOf 'Gene Rearrangement Abnormality'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180936</classIRI>
<classLabel>MYBL1 Gene Fusion Positive</classLabel>
<newAxiom>'MYBL1 Gene Fusion Positive' SubClassOf 'Genetic Fusion Positive'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180935</classIRI>
<classLabel>MYB Gene Fusion Positive</classLabel>
<newAxiom>'MYB Gene Fusion Positive' SubClassOf 'Genetic Fusion Positive'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180934</classIRI>
<classLabel>H3.3 G35X Variant</classLabel>
<newAxiom>'H3.3 G35X Variant' SubClassOf 'Gene_Product_Variant_Of_Gene_Product' some 'Histone H3.3'</newAxiom>
<newAxiom>'H3.3 G35X Variant' SubClassOf 'H3 G35X Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180933</classIRI>
<classLabel>H3 G35X Variant</classLabel>
<newAxiom>'H3 G35X Variant' SubClassOf 'H3 Protein Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180921</classIRI>
<classLabel>Advanced Vaginal Squamous Cell Carcinoma, Not Otherwise Specified</classLabel>
<newAxiom>'Advanced Vaginal Squamous Cell Carcinoma, Not Otherwise Specified' EquivalentTo 'Advanced Vaginal Squamous Cell Carcinoma' and 'Vaginal Squamous Cell Carcinoma, Not Otherwise Specified'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180920</classIRI>
<classLabel>Advanced Vaginal Adenocarcinoma</classLabel>
<newAxiom>'Advanced Vaginal Adenocarcinoma' EquivalentTo 'Advanced Adenocarcinoma' and 'Advanced Vaginal Carcinoma' and 'Metastatic Vaginal Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180929</classIRI>
<classLabel>KMT2A Gene Alteration Positive</classLabel>
<newAxiom>'KMT2A Gene Alteration Positive' SubClassOf 'Genetic Finding'</newAxiom>
<newAxiom>'KMT2A Gene Alteration Positive' SubClassOf 'Positive Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180928</classIRI>
<classLabel>Homologous Recombination Repair Gene Alteration Positive</classLabel>
<newAxiom>'Homologous Recombination Repair Gene Alteration Positive' SubClassOf 'Positive Laboratory Test Result'</newAxiom>
<newAxiom>'Homologous Recombination Repair Gene Alteration Positive' SubClassOf 'Genetic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180927</classIRI>
<classLabel>Regenerative Peripheral Nerve Interface Surgery</classLabel>
<newAxiom>'Regenerative Peripheral Nerve Interface Surgery' SubClassOf 'Surgical Procedure by Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180926</classIRI>
<classLabel>Targeted Muscle Reinnervation</classLabel>
<newAxiom>'Targeted Muscle Reinnervation' SubClassOf 'Surgical Procedure by Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180925</classIRI>
<classLabel>Advanced HER2-Positive Breast Carcinoma</classLabel>
<newAxiom>'Advanced HER2-Positive Breast Carcinoma' EquivalentTo 'Advanced Breast Adenocarcinoma' and 'Metastatic HER2-Positive Breast Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180924</classIRI>
<classLabel>Metastatic HER2-Positive Breast Carcinoma</classLabel>
<newAxiom>'Metastatic HER2-Positive Breast Carcinoma' EquivalentTo 'Metastatic Breast Adenocarcinoma' and 'HER2-Positive Breast Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180923</classIRI>
<classLabel>Recurrent Bronchogenic Carcinoma</classLabel>
<newAxiom>'Recurrent Bronchogenic Carcinoma' EquivalentTo 'Bronchogenic Carcinoma' and 'Recurrent Lung Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180922</classIRI>
<classLabel>Advanced Bronchogenic Carcinoma</classLabel>
<newAxiom>'Advanced Bronchogenic Carcinoma' EquivalentTo 'Advanced Lung Carcinoma' and 'Bronchogenic Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180910</classIRI>
<classLabel>Lenvatinib/Pembrolizumab Regimen</classLabel>
<newAxiom>'Lenvatinib/Pembrolizumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Pembrolizumab'</newAxiom>
<newAxiom>'Lenvatinib/Pembrolizumab Regimen' SubClassOf 'Chemotherapy_Regimen_Has_Component' some 'Lenvatinib Mesylate'</newAxiom>
<newAxiom>'Lenvatinib/Pembrolizumab Regimen' SubClassOf 'Regimen Used to Treat Endometrial Carcinoma'</newAxiom>
<newAxiom>'Lenvatinib/Pembrolizumab Regimen' SubClassOf 'Regimen Used to Treat Malignant Renal Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180919</classIRI>
<classLabel>Human Papillomavirus-Independent Vaginal Squamous Cell Carcinoma</classLabel>
<newAxiom>'Human Papillomavirus-Independent Vaginal Squamous Cell Carcinoma' EquivalentTo 'Human Papillomavirus-Negative Squamous Cell Carcinoma' and 'Vaginal Squamous Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180918</classIRI>
<classLabel>Ambulance</classLabel>
<newAxiom>'Ambulance' SubClassOf 'Device'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180917</classIRI>
<classLabel>Human Papillomavirus-Related Vaginal Squamous Cell Carcinoma</classLabel>
<newAxiom>'Human Papillomavirus-Related Vaginal Squamous Cell Carcinoma' EquivalentTo 'Vaginal Squamous Cell Carcinoma' and 'Human Papillomavirus-Related Squamous Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180916</classIRI>
<classLabel>Appointment</classLabel>
<newAxiom>'Appointment' SubClassOf 'Meeting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180915</classIRI>
<classLabel>Vaginal Squamous Cell Carcinoma</classLabel>
<newAxiom>'Vaginal Squamous Cell Carcinoma' EquivalentTo 'Squamous Cell Carcinoma' and 'Vaginal Carcinoma' and 'Vaginal Squamous Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180914</classIRI>
<classLabel>Vaginal Atrophy</classLabel>
<newAxiom>'Vaginal Atrophy' SubClassOf 'Vaginal Non-Neoplastic Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180913</classIRI>
<classLabel>SARS Coronavirus 2 B.1.621</classLabel>
<newAxiom>'SARS Coronavirus 2 B.1.621' SubClassOf 'SARS Coronavirus 2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180912</classIRI>
<classLabel>Anti-SARS-CoV-2 Monoclonal Antibodies C135-LS/C144-LS</classLabel>
<newAxiom>'Anti-SARS-CoV-2 Monoclonal Antibodies C135-LS/C144-LS' SubClassOf 'Anti-spike Protein SARS-CoV-2 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180911</classIRI>
<classLabel>Interferon Beta-1a Inhalation Solution SNG001</classLabel>
<newAxiom>'Interferon Beta-1a Inhalation Solution SNG001' SubClassOf 'Recombinant Interferon Beta'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180909</classIRI>
<classLabel>EGFR/EGFRvIII Inhibitor CM93</classLabel>
<newAxiom>'EGFR/EGFRvIII Inhibitor CM93' SubClassOf 'Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor'</newAxiom>
<newAxiom>'EGFR/EGFRvIII Inhibitor CM93' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180908</classIRI>
<classLabel>Autologous Multiple Antigen-specific T-cells MASE-T</classLabel>
<newAxiom>'Autologous Multiple Antigen-specific T-cells MASE-T' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous Multiple Antigen-specific T-cells MASE-T' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180907</classIRI>
<classLabel>Anti-PD-1/Anti-TIGIT Bispecific Antibody IBI321</classLabel>
<newAxiom>'Anti-PD-1/Anti-TIGIT Bispecific Antibody IBI321' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-PD-1/Anti-TIGIT Bispecific Antibody IBI321' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180906</classIRI>
<classLabel>Antibody-drug Conjugate RC118</classLabel>
<newAxiom>'Antibody-drug Conjugate RC118' SubClassOf 'Immunoconjugate'</newAxiom>
<newAxiom>'Antibody-drug Conjugate RC118' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180905</classIRI>
<classLabel>Traditional Medicine</classLabel>
<newAxiom>'Traditional Medicine' SubClassOf 'Alternative Medical System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180904</classIRI>
<classLabel>Anti-ILT2/Anti-ILT4 Monoclonal Antibody NGM707</classLabel>
<newAxiom>'Anti-ILT2/Anti-ILT4 Monoclonal Antibody NGM707' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-ILT2/Anti-ILT4 Monoclonal Antibody NGM707' SubClassOf 'Immune Checkpoint Inhibitor'</newAxiom>
<newAxiom>'Anti-ILT2/Anti-ILT4 Monoclonal Antibody NGM707' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180903</classIRI>
<classLabel>Herb</classLabel>
<newAxiom>'Herb' SubClassOf 'Plant-based Natural Product'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180902</classIRI>
<classLabel>EGFR-targeting Agent ABBV-637</classLabel>
<newAxiom>'EGFR-targeting Agent ABBV-637' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
<newAxiom>'EGFR-targeting Agent ABBV-637' SubClassOf 'EGFR-targeting Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180901</classIRI>
<classLabel>AJCC v9 Stage</classLabel>
<newAxiom>'AJCC v9 Stage' SubClassOf 'Disease Stage Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180900</classIRI>
<classLabel>Cervical Cancer pT1b3 TNM Finding v9</classLabel>
<newAxiom>'Cervical Cancer pT1b3 TNM Finding v9' SubClassOf 'Cancer TNM Finding by Site'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>