<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
247
</numberChangedClasses>
<numberNewClasses>
693
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178070</classIRI>
<classLabel>Interim Maintenance Therapy</classLabel>
<deletedAxiom>&apos;Interim Maintenance Therapy&apos; SubClassOf &apos;Chemotherapy&apos;</deletedAxiom>
<newAxiom>&apos;Interim Maintenance Therapy&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178078</classIRI>
<classLabel>Interim Maintenance Therapy</classLabel>
<deletedAxiom>&apos;Interim Maintenance Therapy&apos; SubClassOf &apos;Chemotherapy&apos;</deletedAxiom>
<newAxiom>&apos;Interim Maintenance Therapy&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178271</classIRI>
<classLabel>Locally Advanced Digestive System Neuroendocrine Neoplasm</classLabel>
<deletedAxiom>&apos;Locally Advanced Digestive System Neuroendocrine Neoplasm&apos; EquivalentTo &apos;Metastatic Digestive System Neuroendocrine Neoplasm&apos; and &apos;Locally Advanced Neuroendocrine Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Locally Advanced Digestive System Neuroendocrine Neoplasm&apos; EquivalentTo &apos;Metastatic Digestive System Neuroendocrine Neoplasm&apos; and &apos;Locally Advanced Neuroendocrine Neoplasm&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179181</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C53457</classIRI>
<classLabel>Multiple Osteochondromas</classLabel>
<deletedAxiom>&apos;Multiple Osteochondromas&apos; EquivalentTo &apos;Osteochondroma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Multifocal Lesion&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EXT1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EXT2 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Multiple Osteochondromas&apos; EquivalentTo &apos;Osteochondroma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Multifocal Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C130041</classIRI>
<classLabel>Indolent T-Lymphoblastic Proliferation</classLabel>
<newAxiom>&apos;Indolent T-Lymphoblastic Proliferation&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179053</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3335</classIRI>
<classLabel>Rothmund-Thomson Syndrome</classLabel>
<deletedAxiom>&apos;Rothmund-Thomson Syndrome&apos; EquivalentTo &apos;Genodermatosis&apos; and &apos;Hereditary Neoplastic Syndrome&apos; and &apos;Rare Neoplastic Syndrome&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Skin Photosensitivity&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Skin Rash&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Alopecia&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Osteosarcoma&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Telangiectasia&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Skin Atrophy&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Poikiloderma&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Juvenile Cataract&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Hypogonadism&apos;) and (&apos;Disease_Mapped_To_Chromosome&apos; some &apos;Chromosome 8&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;RECQL4 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Rothmund-Thomson Syndrome&apos; EquivalentTo &apos;Genodermatosis&apos; and &apos;Hereditary Neoplastic Syndrome&apos; and &apos;Rare Neoplastic Syndrome&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Skin Photosensitivity&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Skin Rash&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Alopecia&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Telangiectasia&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Skin Atrophy&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Poikiloderma&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Hypogonadism&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C53677</classIRI>
<classLabel>Intimal Sarcoma</classLabel>
<deletedAxiom>&apos;Intimal Sarcoma&apos; EquivalentTo &apos;Spindle Cell Sarcoma&apos; and &apos;Malignant Soft Tissue Tumor of Uncertain Differentiation&apos; and &apos;Soft Tissue Sarcoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Blood Vessel&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Tunica Intima&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Intraluminal Tumor Growth&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 4q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 12q13-14&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Arterial Embolic Tumor Spread&apos;)</deletedAxiom>
<newAxiom>&apos;Intimal Sarcoma&apos; EquivalentTo &apos;Spindle Cell Sarcoma&apos; and &apos;Malignant Soft Tissue Tumor of Uncertain Differentiation&apos; and &apos;Soft Tissue Sarcoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Blood Vessel&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Tunica Intima&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Intraluminal Tumor Growth&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 4q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 12q13-14&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Arterial Embolic Tumor Spread&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;MDM2 Gene Amplification&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3297</classIRI>
<classLabel>Osteoid Osteoma</classLabel>
<deletedAxiom>&apos;Osteoid Osteoma&apos; EquivalentTo &apos;Benign Bone Neoplasm&apos; and &apos;Benign Osteogenic Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Surface&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Bone Tissue&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Pain&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Nidus Formation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lesion with Diameter of 2 cm or Less&apos;) and (&apos;Disease_Excludes_Normal_Tissue_Origin&apos; some &apos;Medullary Bone&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Lesion with Diameter Greater than 2 cm&apos;)</deletedAxiom>
<newAxiom>&apos;Osteoid Osteoma&apos; EquivalentTo &apos;Benign Bone Neoplasm&apos; and &apos;Benign Osteogenic Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Surface&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Bone Tissue&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Pain&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Nidus Formation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lesion with Diameter of 2 cm or Less&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178557) and (&apos;Disease_Excludes_Normal_Tissue_Origin&apos; some &apos;Medullary Bone&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Lesion with Diameter Greater than 2 cm&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3294</classIRI>
<classLabel>Osteoblastoma</classLabel>
<deletedAxiom>&apos;Osteoblastoma&apos; EquivalentTo &apos;Benign Bone Neoplasm&apos; and &apos;Benign Osteogenic Neoplasm&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Osteoclast-Like Giant Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lesion with Diameter Greater than 2 cm&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cystic Change&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Epithelioid Osteoblast&apos;)</deletedAxiom>
<newAxiom>&apos;Osteoblastoma&apos; EquivalentTo &apos;Benign Bone Neoplasm&apos; and &apos;Benign Osteogenic Neoplasm&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Osteoclast-Like Giant Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lesion with Diameter Greater than 2 cm&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178557) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cystic Change&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Epithelioid Osteoblast&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3295</classIRI>
<classLabel>Osteochondroma</classLabel>
<deletedAxiom>&apos;Osteochondroma&apos; EquivalentTo &apos;Benign Bone Neoplasm&apos; and &apos;Benign Chondrogenic Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cartilage&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Chondrocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Chondrocyte&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(8q24.1)&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Mitotic Activity&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Increased Cellularity Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Atypia&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EXT1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Osteochondroma&apos; EquivalentTo &apos;Benign Bone Neoplasm&apos; and &apos;Benign Chondrogenic Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cartilage&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Chondrocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Chondrocyte&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(8q24.1)&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Mitotic Activity&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Increased Cellularity Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Atypia&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EXT1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EXT2 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178471) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178472)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3204</classIRI>
<classLabel>Lymphangioleiomyoma</classLabel>
<deletedAxiom>&apos;Lymphangioleiomyoma&apos; EquivalentTo &apos;PEComa&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Lymphatic Vessel&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Smooth Muscle Component Present&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Spindle Cell&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Tuberous Sclerosis&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;TSC2 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TSC2 Gene Inactivation&apos;)</deletedAxiom>
<newAxiom>&apos;Lymphangioleiomyoma&apos; EquivalentTo &apos;PEComa&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Lymphatic Vessel&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Smooth Muscle Component Present&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Spindle Cell&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Tuberous Sclerosis&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3184</classIRI>
<classLabel>Adult T-Cell Leukemia/Lymphoma</classLabel>
<deletedAxiom>&apos;Adult T-Cell Leukemia/Lymphoma&apos; EquivalentTo &apos;HTLV-1-Related Malignant Neoplasm&apos; and &apos;Virus-Related Lymphoma&apos; and &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and &apos;Aggressive Adult Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;CD4-Positive T-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;)</deletedAxiom>
<newAxiom>&apos;Adult T-Cell Leukemia/Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178547 and &apos;HTLV-1-Related Malignant Neoplasm&apos; and &apos;Virus-Related Lymphoma&apos; and &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and &apos;Aggressive Adult Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;CD4-Positive T-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C53971</classIRI>
<classLabel>Monostotic Fibrous Dysplasia</classLabel>
<deletedAxiom>&apos;Monostotic Fibrous Dysplasia&apos; SubClassOf &apos;Fibrous Dysplasia&apos;</deletedAxiom>
<newAxiom>&apos;Monostotic Fibrous Dysplasia&apos; EquivalentTo &apos;Fibrous Dysplasia&apos; and (&apos;Disease_Excludes_Finding&apos; some &apos;Multifocal Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3745</classIRI>
<classLabel>Clear Cell Sarcoma of Soft Tissue</classLabel>
<deletedAxiom>&apos;Clear Cell Sarcoma of Soft Tissue&apos; EquivalentTo &apos;Malignant Soft Tissue Tumor of Uncertain Differentiation&apos; and &apos;Soft Tissue Sarcoma&apos; and ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(12;22)(q13;q12)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-ATF1 Fusion Protein Expression&apos;)) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Polygonal Cell with Eosinophilic Cytoplasm&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Nested Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Fascicular Pattern&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Spindle Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Wreath-Like Multinucleated Giant Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 7&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Melanosomes Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Slow Growing Mass&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/ATF1 Fusion Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Clear Cell Sarcoma of Soft Tissue&apos; EquivalentTo &apos;Malignant Soft Tissue Tumor of Uncertain Differentiation&apos; and &apos;Soft Tissue Sarcoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Polygonal Cell with Eosinophilic Cytoplasm&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Nested Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Fascicular Pattern&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Spindle Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Wreath-Like Multinucleated Giant Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(2;22)(q34;q12)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(12;22)(q13;q12)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 7&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Melanosomes Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Slow Growing Mass&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/ATF1 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/CREB1 Fusion Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-CREB1 Fusion Protein Expression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-ATF1 Fusion Protein Expression&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3769</classIRI>
<classLabel>Endometrioid Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Endometrioid Adenocarcinoma&apos; EquivalentTo &apos;Adenocarcinoma&apos; and &apos;Malignant Female Reproductive System Neoplasm&apos; and &apos;Endometrioid Tumor&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Female Reproductive System&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Malignant Glandular Epithelium Resembling the Normal Endometrium Present&apos;)</deletedAxiom>
<newAxiom>&apos;Endometrioid Adenocarcinoma&apos; EquivalentTo &apos;Adenocarcinoma&apos; and &apos;Endometrioid Tumor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3714</classIRI>
<classLabel>Epithelioid Sarcoma</classLabel>
<deletedAxiom>&apos;Epithelioid Sarcoma&apos; EquivalentTo &apos;Malignant Soft Tissue Tumor of Uncertain Differentiation&apos; and &apos;FNCLCC Sarcoma Grade 3&apos; and &apos;Soft Tissue Sarcoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Epithelioid Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 8p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 22q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;i(8)(q10)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 11q13&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Change&apos;)</deletedAxiom>
<newAxiom>&apos;Epithelioid Sarcoma&apos; EquivalentTo &apos;Malignant Soft Tissue Tumor of Uncertain Differentiation&apos; and &apos;FNCLCC Sarcoma Grade 3&apos; and &apos;Soft Tissue Sarcoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Epithelioid Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 8p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 22q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;i(8)(q10)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 11q13&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Loss of INI 1 Protein Expression&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Change&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158493</classIRI>
<classLabel>Platinum-Resistant Lung Small Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Platinum-Resistant Lung Small Cell Carcinoma&apos; EquivalentTo &apos;Lung Small Cell Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Platinum Resistance&apos;)</deletedAxiom>
<newAxiom>&apos;Platinum-Resistant Lung Small Cell Carcinoma&apos; EquivalentTo &apos;Refractory Lung Small Cell Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Platinum Resistance&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3725</classIRI>
<classLabel>Lymphangioleiomyomatosis</classLabel>
<deletedAxiom>&apos;Lymphangioleiomyomatosis&apos; EquivalentTo &apos;PEComa&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Multifocal Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Smooth Muscle Component Present&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Tuberous Sclerosis&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Localized Disease&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;TSC2 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TSC2 Gene Inactivation&apos;)</deletedAxiom>
<newAxiom>&apos;Lymphangioleiomyomatosis&apos; EquivalentTo &apos;PEComa&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Multifocal Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Smooth Muscle Component Present&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Tuberous Sclerosis&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Localized Disease&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3460</classIRI>
<classLabel>Grade 3 Follicular Lymphoma</classLabel>
<deletedAxiom>&apos;Grade 3 Follicular Lymphoma&apos; EquivalentTo &apos;Follicular Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Centroblast&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Nodular Pattern&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 3&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(14;18)(q32;q21)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(9;14)(p13;q32)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(2;18)(p12;q21)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(6q21)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(6q23)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(6q25-27)&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BCL2 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal BCL2 Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal BCL6 Gene Rearrangement&apos;)</deletedAxiom>
<newAxiom>&apos;Grade 3 Follicular Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178541 and &apos;Follicular Lymphoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Centroblast&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Nodular Pattern&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 3&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(14;18)(q32;q21)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(9;14)(p13;q32)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(2;18)(p12;q21)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(6q21)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(6q23)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(6q25-27)&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BCL2 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal BCL2 Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal BCL6 Gene Rearrangement&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158421</classIRI>
<classLabel>Recurrent Endometrioid Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Recurrent Endometrioid Adenocarcinoma&apos; EquivalentTo &apos;Recurrent Adenocarcinoma&apos; and &apos;Endometrioid Adenocarcinoma&apos; and &apos;Recurrent Female Reproductive System Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Endometrioid Adenocarcinoma&apos; EquivalentTo &apos;Recurrent Adenocarcinoma&apos; and &apos;Endometrioid Adenocarcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158108</classIRI>
<classLabel>VEGF Overexpression Positive</classLabel>
<deletedAxiom>&apos;VEGF Overexpression Positive&apos; SubClassOf &apos;Elevated Expression&apos;</deletedAxiom>
<newAxiom>&apos;VEGF Overexpression Positive&apos; SubClassOf &apos;Growth Factor Overexpression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3808</classIRI>
<classLabel>Rhabdoid Tumor</classLabel>
<deletedAxiom>&apos;Rhabdoid Tumor&apos; EquivalentTo &apos;Embryonal Neoplasm&apos; and ((&apos;Disease_Has_Finding&apos; some &apos;Intermediate Filaments Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Intracytoplasmic Eosinophilic Inclusion&apos;)) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Cell with Large Nucleus and Abundant Eosinophilic Cytoplasm&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 4&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Non-Neoplastic Osteoclast-Like Giant Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;High Mitotic Activity&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;SMARCB1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Rhabdoid Tumor&apos; EquivalentTo &apos;Embryonal Neoplasm&apos; and ((&apos;Disease_Has_Finding&apos; some &apos;Intermediate Filaments Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Intracytoplasmic Eosinophilic Inclusion&apos;)) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Cell with Large Nucleus and Abundant Eosinophilic Cytoplasm&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 4&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Non-Neoplastic Osteoclast-Like Giant Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 22&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Loss of INI 1 Protein Expression&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;High Mitotic Activity&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;SMARCB1 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;SMARCB1 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150716</classIRI>
<classLabel>Mutation-Negative Lynch Syndrome</classLabel>
<deletedAxiom>&apos;Mutation-Negative Lynch Syndrome&apos; SubClassOf &apos;Genetic Finding&apos;</deletedAxiom>
<deletedAxiom>&apos;Mutation-Negative Lynch Syndrome&apos; SubClassOf &apos;Negative Test Result&apos;</deletedAxiom>
<newAxiom>&apos;Mutation-Negative Lynch Syndrome&apos; SubClassOf &apos;Gene Variant Negative&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48876</classIRI>
<classLabel>Dedifferentiated Chordoma</classLabel>
<deletedAxiom>&apos;Dedifferentiated Chordoma&apos; EquivalentTo &apos;Chordoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Sarcomatous Component Present&apos;)</deletedAxiom>
<newAxiom>&apos;Dedifferentiated Chordoma&apos; EquivalentTo &apos;Chordoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Physaliphorous Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Epithelioid Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lobulated Growth Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myxoid Stroma Formation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Sarcomatous Component Present&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125408</classIRI>
<classLabel>Problem with Sexual Interest or Activity</classLabel>
<deletedAxiom>&apos;Problem with Sexual Interest or Activity&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Problem with Sexual Interest or Activity&apos; SubClassOf &apos;Sex Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125355</classIRI>
<classLabel>How Much Distress Change in the Way Food Tastes</classLabel>
<newAxiom>&apos;How Much Distress Change in the Way Food Tastes&apos; SubClassOf &apos;Taste Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125349</classIRI>
<classLabel>How Much Distress Itching</classLabel>
<newAxiom>&apos;How Much Distress Itching&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125316</classIRI>
<classLabel>Usual Severity Problems with Sexual Interest or Activity</classLabel>
<deletedAxiom>&apos;Usual Severity Problems with Sexual Interest or Activity&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Usual Severity Problems with Sexual Interest or Activity&apos; SubClassOf &apos;Sex Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125317</classIRI>
<classLabel>Usual Severity Itching</classLabel>
<deletedAxiom>&apos;Usual Severity Itching&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Usual Severity Itching&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125323</classIRI>
<classLabel>Usual Severity Change in the Way Food Tastes</classLabel>
<deletedAxiom>&apos;Usual Severity Change in the Way Food Tastes&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Usual Severity Change in the Way Food Tastes&apos; SubClassOf &apos;Taste Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150485</classIRI>
<classLabel>EGFRvIII Positive</classLabel>
<newAxiom>&apos;EGFRvIII Positive&apos; SubClassOf &apos;Receptor Status&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150489</classIRI>
<classLabel>Severe Mosquito Bite Allergy</classLabel>
<newAxiom>&apos;Severe Mosquito Bite Allergy&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179053</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150495</classIRI>
<classLabel>Intestinal T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Intestinal T-Cell Lymphoma&apos; EquivalentTo &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and &apos;Digestive System Non-Hodgkin Lymphoma&apos; and &apos;Malignant Intestinal Neoplasm&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Intraepithelial T-Lymphocyte&apos;)</deletedAxiom>
<newAxiom>&apos;Intestinal T-Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178547 and &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and &apos;Digestive System Non-Hodgkin Lymphoma&apos; and &apos;Malignant Intestinal Neoplasm&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Intraepithelial T-Lymphocyte&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150132</classIRI>
<classLabel>Recurrent Monomorphic Epitheliotropic Intestinal T-cell Lymphoma</classLabel>
<deletedAxiom>&apos;Recurrent Monomorphic Epitheliotropic Intestinal T-cell Lymphoma&apos; EquivalentTo &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and &apos;Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Monomorphic Epitheliotropic Intestinal T-cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178554 and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and &apos;Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34585</classIRI>
<classLabel>Endomyocardial Fibrosis</classLabel>
<deletedAxiom>&apos;Endomyocardial Fibrosis&apos; SubClassOf &apos;Non-Neoplastic Heart Disorder&apos;</deletedAxiom>
<newAxiom>&apos;Endomyocardial Fibrosis&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178564</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125213</classIRI>
<classLabel>Voltage-Dependent Calcium Channel Gamma-Like Subunit</classLabel>
<deletedAxiom>&apos;Voltage-Dependent Calcium Channel Gamma-Like Subunit&apos; EquivalentTo &apos;Regulatory Protein&apos; and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cellular Membrane&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transmembrane Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Calcium Channel Inhibition&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TMEM37 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Voltage-Dependent Calcium Channel Gamma-Like Subunit&apos; EquivalentTo &apos;Regulatory Protein&apos; and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cellular Membrane&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Transmembrane Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Transmembrane Transport&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Calcium Channel Inhibition&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Voltage-Gated Potassium Ion Channel Activation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;TMEM37 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34609</classIRI>
<classLabel>Fibrous Dysplasia</classLabel>
<deletedAxiom>&apos;Fibrous Dysplasia&apos; SubClassOf &apos;Bone Tumor of Undefined Neoplastic Nature&apos;</deletedAxiom>
<deletedAxiom>&apos;Fibrous Dysplasia&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;GNAS Gene&apos;</deletedAxiom>
<newAxiom>&apos;Fibrous Dysplasia&apos; EquivalentTo &apos;Benign Bone Neoplasm&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Medullary Bone&apos;) and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178603) and (&apos;Disease_Has_Finding&apos; some &apos;Fibrotic Stroma Formation&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;GNAS Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;GNAS Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34610</classIRI>
<classLabel>Polyostotic Fibrous Dysplasia</classLabel>
<deletedAxiom>&apos;Polyostotic Fibrous Dysplasia&apos; SubClassOf &apos;Fibrous Dysplasia&apos;</deletedAxiom>
<newAxiom>&apos;Polyostotic Fibrous Dysplasia&apos; EquivalentTo &apos;Fibrous Dysplasia&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Multifocal Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125284</classIRI>
<classLabel>How Often Problems with Sexual Interest or Activity</classLabel>
<newAxiom>&apos;How Often Problems with Sexual Interest or Activity&apos; SubClassOf &apos;Sex Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125285</classIRI>
<classLabel>How Often Itching</classLabel>
<newAxiom>&apos;How Often Itching&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125291</classIRI>
<classLabel>How Often Change in Food Tastes</classLabel>
<newAxiom>&apos;How Often Change in Food Tastes&apos; SubClassOf &apos;Taste Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34726</classIRI>
<classLabel>Infectious Mononucleosis</classLabel>
<deletedAxiom>&apos;Infectious Mononucleosis&apos; EquivalentTo &apos;EBV Infection&apos; and &apos;Benign Lymphoproliferative Disorder&apos; and (((&apos;Disease_Has_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Splenic Rupture&apos;)) or ((&apos;Disease_Has_Finding&apos; some &apos;Atypical Lymphocytes Present in Peripheral Blood&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Polymorphic Cellular Infiltrate&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Diffuse Immunoblastic Proliferation&apos;))) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;EBV-Specific Cytotoxic T-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Reactive Lymphocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Acute Hepatitis&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Clonal Antigen Receptor Gene Rearrangement&apos;)</deletedAxiom>
<newAxiom>&apos;Infectious Mononucleosis&apos; EquivalentTo &apos;EBV Infection&apos; and &apos;Benign Lymphoproliferative Disorder&apos; and (((&apos;Disease_Has_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Splenic Rupture&apos;)) or ((&apos;Disease_Has_Finding&apos; some &apos;Atypical Lymphocytes Present in Peripheral Blood&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Polymorphic Cellular Infiltrate&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Diffuse Immunoblastic Proliferation&apos;))) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Reactive Lymphocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Acute Hepatitis&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Clonal Antigen Receptor Gene Rearrangement&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125077</classIRI>
<classLabel>Bleed Easily</classLabel>
<deletedAxiom>&apos;Bleed Easily&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Bleed Easily&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179032</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125018</classIRI>
<classLabel>How Big a Problem is Bleeding with Urination</classLabel>
<newAxiom>&apos;How Big a Problem is Bleeding with Urination&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179032</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C139666</classIRI>
<classLabel>BCOR/CCNB3 Fusion Gene</classLabel>
<newAxiom>&apos;BCOR/CCNB3 Fusion Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178466</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C105940</classIRI>
<classLabel>Serum Amyloid A</classLabel>
<newAxiom>&apos;Serum Amyloid A&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Inflammatory Response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C93268</classIRI>
<classLabel>Rhabdoid Tumor Predisposition Syndrome</classLabel>
<deletedAxiom>&apos;Rhabdoid Tumor Predisposition Syndrome&apos; EquivalentTo &apos;Hereditary Neoplastic Syndrome&apos; and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Medulloblastoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Choroid Plexus Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Extrarenal Rhabdoid Tumor&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Supratentorial Embryonal Tumor, Not Otherwise Specified&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Rhabdoid Tumor of the Kidney&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Atypical Teratoid/Rhabdoid Tumor&apos;)</deletedAxiom>
<newAxiom>&apos;Rhabdoid Tumor Predisposition Syndrome&apos; EquivalentTo &apos;Hereditary Neoplastic Syndrome&apos; and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Medulloblastoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Choroid Plexus Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Supratentorial Embryonal Tumor, Not Otherwise Specified&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Atypical Teratoid/Rhabdoid Tumor&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20495</classIRI>
<classLabel>Interferon Beta</classLabel>
<deletedAxiom>&apos;Interferon Beta&apos; SubClassOf &apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Epithelial Cell&apos;</deletedAxiom>
<deletedAxiom>&apos;Interferon Beta&apos; SubClassOf &apos;Interferon&apos;</deletedAxiom>
<deletedAxiom>&apos;Interferon Beta&apos; SubClassOf &apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Glycoprotein&apos;</deletedAxiom>
<deletedAxiom>&apos;Interferon Beta&apos; SubClassOf &apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Fibroblast&apos;</deletedAxiom>
<deletedAxiom>&apos;Interferon Beta&apos; SubClassOf &apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Macrophage&apos;</deletedAxiom>
<newAxiom>&apos;Interferon Beta&apos; EquivalentTo &apos;Interferon&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Natural Killer Cell-Mediated Cytotoxicity Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cytokine-Cytokine Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cytosolic DNA-Sensing Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Toll-Like Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;NOD-Like Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;RIG-I-Like Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Jak-STAT Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Chagas Disease Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Regulation of Nuclear SMAD2/3 Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Shigellosis Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Glycoprotein&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Fibroblast&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Macrophage&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Epithelial Cell&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Humoral Immunity&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;B Cell Proliferation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Antitumor Response&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Antimicrobial Effect&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178570)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54090</classIRI>
<classLabel>Neoplastic Vacuolated Stromal Cell</classLabel>
<newAxiom>&apos;Neoplastic Vacuolated Stromal Cell&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178561</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29085</classIRI>
<classLabel>HIV Peptide Vaccine</classLabel>
<newAxiom>&apos;HIV Peptide Vaccine&apos; SubClassOf &apos;HIV Vaccine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C105619</classIRI>
<classLabel>As Bad as You Can Imagine</classLabel>
<deletedAxiom>&apos;As Bad as You Can Imagine&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;As Bad as You Can Imagine&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178394</classIRI>
<classLabel>Rhabdoid Tumor Predisposition Syndrome 2</classLabel>
<deletedAxiom>&apos;Rhabdoid Tumor Predisposition Syndrome 2&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SMARCA4 Gene&apos;</deletedAxiom>
<deletedAxiom>&apos;Rhabdoid Tumor Predisposition Syndrome 2&apos; SubClassOf &apos;Rhabdoid Tumor Predisposition Syndrome&apos;</deletedAxiom>
<newAxiom>&apos;Rhabdoid Tumor Predisposition Syndrome 2&apos; EquivalentTo &apos;Rhabdoid Tumor Predisposition Syndrome&apos; and (&apos;Disease_Mapped_To_Gene&apos; some &apos;SMARCA4 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178392</classIRI>
<classLabel>Genetic Predisposition to Non-Syndromic Wilms Tumor</classLabel>
<deletedAxiom>&apos;Genetic Predisposition to Non-Syndromic Wilms Tumor&apos; SubClassOf &apos;Genetic Predisposition to Tumor&apos;</deletedAxiom>
<newAxiom>&apos;Genetic Predisposition to Non-Syndromic Wilms Tumor&apos; SubClassOf &apos;Genetic Predisposition to Malignant Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178393</classIRI>
<classLabel>Rhabdoid Tumor Predisposition Syndrome 1</classLabel>
<deletedAxiom>&apos;Rhabdoid Tumor Predisposition Syndrome 1&apos; SubClassOf &apos;Rhabdoid Tumor Predisposition Syndrome&apos;</deletedAxiom>
<deletedAxiom>&apos;Rhabdoid Tumor Predisposition Syndrome 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;SMARCB1 Gene&apos;</deletedAxiom>
<newAxiom>&apos;Rhabdoid Tumor Predisposition Syndrome 1&apos; EquivalentTo &apos;Rhabdoid Tumor Predisposition Syndrome&apos; and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Extrarenal Rhabdoid Tumor&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Rhabdoid Tumor of the Kidney&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;SMARCB1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178377</classIRI>
<classLabel>Genetic Predisposition to Leukemia</classLabel>
<deletedAxiom>&apos;Genetic Predisposition to Leukemia&apos; SubClassOf &apos;Genetic Predisposition to Cancer&apos;</deletedAxiom>
<newAxiom>&apos;Genetic Predisposition to Leukemia&apos; SubClassOf &apos;Genetic Predisposition to Malignant Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178378</classIRI>
<classLabel>Genetic Predisposition to Cancer</classLabel>
<deletedAxiom>&apos;Genetic Predisposition to Cancer&apos; SubClassOf &apos;Finding by Cause&apos;</deletedAxiom>
<newAxiom>&apos;Genetic Predisposition to Cancer&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29321</classIRI>
<classLabel>Phosphate Buffer</classLabel>
<deletedAxiom>&apos;Phosphate Buffer&apos; SubClassOf &apos;Reagent&apos;</deletedAxiom>
<newAxiom>&apos;Phosphate Buffer&apos; SubClassOf &apos;Buffer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118271</classIRI>
<classLabel>Have Vaginal Itching or Irritation</classLabel>
<newAxiom>&apos;Have Vaginal Itching or Irritation&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118272</classIRI>
<classLabel>Have Vaginal Bleeding or Spotting</classLabel>
<newAxiom>&apos;Have Vaginal Bleeding or Spotting&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179032</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118276</classIRI>
<classLabel>Have Gained Weight</classLabel>
<deletedAxiom>&apos;Have Gained Weight&apos; SubClassOf &apos;Have Symptom or Condition Question&apos;</deletedAxiom>
<newAxiom>&apos;Have Gained Weight&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157821</classIRI>
<classLabel>Cognitive Behavioral Therapy for Insomnia</classLabel>
<deletedAxiom>&apos;Cognitive Behavioral Therapy for Insomnia&apos; SubClassOf &apos;Behavioral Intervention&apos;</deletedAxiom>
<newAxiom>&apos;Cognitive Behavioral Therapy for Insomnia&apos; SubClassOf &apos;Cognitive Behavior Therapy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54718</classIRI>
<classLabel>Adenocarcinoma Cell with Abundant Finely Vacuolated Cytoplasm</classLabel>
<newAxiom>&apos;Adenocarcinoma Cell with Abundant Finely Vacuolated Cytoplasm&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178561</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118394</classIRI>
<classLabel>MLH1 Gene Mutation</classLabel>
<newAxiom>&apos;MLH1 Gene Mutation&apos; SubClassOf &apos;Gene_Mutant_Encodes_Gene_Product_Sequence_Variation&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178530</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118395</classIRI>
<classLabel>MSH6 Gene Mutation</classLabel>
<newAxiom>&apos;MSH6 Gene Mutation&apos; SubClassOf &apos;Gene_Mutant_Encodes_Gene_Product_Sequence_Variation&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178531</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118397</classIRI>
<classLabel>PMS2 Gene Mutation</classLabel>
<newAxiom>&apos;PMS2 Gene Mutation&apos; SubClassOf &apos;Gene_Mutant_Encodes_Gene_Product_Sequence_Variation&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178529</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40239</classIRI>
<classLabel>Cervical Melanoma</classLabel>
<deletedAxiom>&apos;Cervical Melanoma&apos; EquivalentTo &apos;Mucosal Melanoma&apos; and &apos;Malignant Cervical Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cervix Uteri&apos;) and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Female Reproductive System&apos;) and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Uterus&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Cervical Melanoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178437 and &apos;Malignant Cervical Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Cervix Uteri&apos;) and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Uterus&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157622</classIRI>
<classLabel>Platinum-Resistant Primary Peritoneal Carcinoma</classLabel>
<deletedAxiom>&apos;Platinum-Resistant Primary Peritoneal Carcinoma&apos; EquivalentTo &apos;Refractory Primary Peritoneal Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Platinum Resistance&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Platinum Sensitivity&apos;)</deletedAxiom>
<newAxiom>&apos;Platinum-Resistant Primary Peritoneal Carcinoma&apos; EquivalentTo &apos;Refractory Primary Peritoneal Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Platinum Resistance&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157694</classIRI>
<classLabel>Refractory Monomorphic Epitheliotropic Intestinal T-cell Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory Monomorphic Epitheliotropic Intestinal T-cell Lymphoma&apos; EquivalentTo &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and &apos;Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Monomorphic Epitheliotropic Intestinal T-cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178556 and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and &apos;Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88334</classIRI>
<classLabel>Non-Adjuvanted A(H1N1) Influenza Vaccine</classLabel>
<deletedAxiom>&apos;Non-Adjuvanted A(H1N1) Influenza Vaccine&apos; SubClassOf &apos;Viral Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;Non-Adjuvanted A(H1N1) Influenza Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178427</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88320</classIRI>
<classLabel>AS03-Adjuvanted H1N1 Pandemic Influenza Vaccine</classLabel>
<newAxiom>&apos;AS03-Adjuvanted H1N1 Pandemic Influenza Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178427</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40459</classIRI>
<classLabel>ATM Gene Mutation</classLabel>
<newAxiom>&apos;ATM Gene Mutation&apos; SubClassOf &apos;Gene_Mutant_Encodes_Gene_Product_Sequence_Variation&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178532</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157020</classIRI>
<classLabel>Have Urinary Incontinence</classLabel>
<newAxiom>&apos;Have Urinary Incontinence&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178809</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137871</classIRI>
<classLabel>Magnetic Resonance Imaging of the Whole Body without Contrast</classLabel>
<newAxiom>&apos;Magnetic Resonance Imaging of the Whole Body without Contrast&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178628</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2643</classIRI>
<classLabel>Trivalent Influenza Vaccine</classLabel>
<newAxiom>&apos;Trivalent Influenza Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178427</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137921</classIRI>
<classLabel>Magnetic Resonance Imaging of the Whole Body with and without Contrast</classLabel>
<deletedAxiom>&apos;Magnetic Resonance Imaging of the Whole Body with and without Contrast&apos; SubClassOf &apos;Magnetic Resonance Imaging&apos;</deletedAxiom>
<newAxiom>&apos;Magnetic Resonance Imaging of the Whole Body with and without Contrast&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178628</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137930</classIRI>
<classLabel>Multiphasic Magnetic Resonance Imaging of the Abdomen</classLabel>
<newAxiom>&apos;Multiphasic Magnetic Resonance Imaging of the Abdomen&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179164</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137931</classIRI>
<classLabel>Multiphasic Magnetic Resonance imaging of the Abdomen and Pelvis</classLabel>
<newAxiom>&apos;Multiphasic Magnetic Resonance imaging of the Abdomen and Pelvis&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179164</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2947</classIRI>
<classLabel>Chordoma</classLabel>
<deletedAxiom>&apos;Chordoma&apos; EquivalentTo &apos;Malignant Bone Neoplasm&apos; and &apos;Notochordal Tumor&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Lobulated Growth Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myxoid Stroma Formation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Solitary Mass&apos;)</deletedAxiom>
<newAxiom>&apos;Chordoma&apos; EquivalentTo &apos;Malignant Bone Neoplasm&apos; and &apos;Notochordal Tumor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35712</classIRI>
<classLabel>Follicular Bronchitis/Bronchiolitis</classLabel>
<deletedAxiom>&apos;Follicular Bronchitis/Bronchiolitis&apos; EquivalentTo &apos;Benign Lymphoproliferative Disorder&apos; and &apos;Chronic Lung Disorder&apos; and ((&apos;Disease_Has_Finding&apos; some &apos;Nodular Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lymphocytic Infiltrate&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Peribronchial and Lobular Septal Involvement Only&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphoplasmacytic Infiltrate&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Reactive Germinal Centers Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Lymphoepithelial Lesion&apos;)) and (&apos;Disease_Has_Associated_Anatomic_Site&apos; some &apos;Lung&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Bronchus-Associated Lymphoid Tissue&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Mature Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Reactive Lymphocyte&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Rheumatologic Disorder&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Immunodeficiency Syndrome&apos;)</deletedAxiom>
<newAxiom>&apos;Follicular Bronchitis/Bronchiolitis&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179052 and &apos;Benign Lymphoproliferative Disorder&apos; and &apos;Chronic Lung Disorder&apos; and ((&apos;Disease_Has_Finding&apos; some &apos;Nodular Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lymphocytic Infiltrate&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Peribronchial and Lobular Septal Involvement Only&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphoplasmacytic Infiltrate&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Reactive Germinal Centers Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Lymphoepithelial Lesion&apos;)) and (&apos;Disease_Has_Associated_Anatomic_Site&apos; some &apos;Lung&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Bronchus-Associated Lymphoid Tissue&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Mature Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Reactive Lymphocyte&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Rheumatologic Disorder&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Immunodeficiency Syndrome&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2912</classIRI>
<classLabel>Burkitt Lymphoma</classLabel>
<deletedAxiom>&apos;Burkitt Lymphoma&apos; EquivalentTo &apos;Mature B-Cell Non-Hodgkin Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Germinal Center B-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized B-Lymphocyte with Basophilic Cytoplasm&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Heavy Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;MYC Gene Amplification&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Starry Sky Pattern&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(2;8)(p11;q24)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(8;14)(q24;q32)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(8;22)(q24;q11)&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Bulky Disease&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Tumor Lysis Syndrome&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MYC Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Burkitt Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178541 and &apos;Mature B-Cell Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Germinal Center B-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized B-Lymphocyte with Basophilic Cytoplasm&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Heavy Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;MYC Gene Amplification&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Starry Sky Pattern&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(2;8)(p11;q24)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(8;14)(q24;q32)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(8;22)(q24;q11)&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Bulky Disease&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Tumor Lysis Syndrome&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MYC Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C69144</classIRI>
<classLabel>Recurrent Grade III Lymphomatoid Granulomatosis</classLabel>
<deletedAxiom>&apos;Recurrent Grade III Lymphomatoid Granulomatosis&apos; EquivalentTo &apos;Recurrent EBV-Related Lymphoma&apos; and &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Grade III Lymphomatoid Granulomatosis&apos; and &apos;Recurrent Lymphomatoid Granulomatosis&apos; and &apos;Recurrent Diffuse Large B-Cell Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Grade III Lymphomatoid Granulomatosis&apos; EquivalentTo &apos;Recurrent EBV-Related Lymphoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178553 and &apos;Grade III Lymphomatoid Granulomatosis&apos; and &apos;Recurrent Lymphomatoid Granulomatosis&apos; and &apos;Recurrent Diffuse Large B-Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104931</classIRI>
<classLabel>Have Itch</classLabel>
<newAxiom>&apos;Have Itch&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104934</classIRI>
<classLabel>Notice Change in the Way Food Tastes</classLabel>
<newAxiom>&apos;Notice Change in the Way Food Tastes&apos; SubClassOf &apos;Taste Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138027</classIRI>
<classLabel>Recurrent Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type</classLabel>
<deletedAxiom>&apos;Recurrent Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; EquivalentTo &apos;Recurrent Primary Cutaneous Lymphoma&apos; and &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; and &apos;Recurrent Diffuse Large B-Cell Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; EquivalentTo &apos;Recurrent Primary Cutaneous Lymphoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178553 and &apos;Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; and &apos;Recurrent Diffuse Large B-Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138028</classIRI>
<classLabel>Refractory Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type</classLabel>
<deletedAxiom>&apos;Refractory Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; EquivalentTo &apos;Refractory Primary Cutaneous Lymphoma&apos; and &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; and &apos;Refractory Diffuse Large B-Cell Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; EquivalentTo &apos;Refractory Primary Cutaneous Lymphoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178555 and &apos;Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; and &apos;Refractory Diffuse Large B-Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138131</classIRI>
<classLabel>Magnetic Resonance Whole Body Diffusion-Weighted Imaging</classLabel>
<newAxiom>&apos;Magnetic Resonance Whole Body Diffusion-Weighted Imaging&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178628</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118832</classIRI>
<classLabel>Bothered by Vaginal Discharge or Bleeding</classLabel>
<newAxiom>&apos;Bothered by Vaginal Discharge or Bleeding&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179032</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118601</classIRI>
<classLabel>Able to Do Usual Activities</classLabel>
<deletedAxiom>&apos;Able to Do Usual Activities&apos; SubClassOf &apos;Ability Question&apos;</deletedAxiom>
<newAxiom>&apos;Able to Do Usual Activities&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80936</classIRI>
<classLabel>Poloxamer 188</classLabel>
<newAxiom>&apos;Poloxamer 188&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178536</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132215</classIRI>
<classLabel>Past Seven Days How Much Urinary Incontinence Interfered with Usual or Daily Activities</classLabel>
<newAxiom>&apos;Past Seven Days How Much Urinary Incontinence Interfered with Usual or Daily Activities&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178809</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107207</classIRI>
<classLabel>Distress over Physical Problem with Dry or Itchy Skin</classLabel>
<newAxiom>&apos;Distress over Physical Problem with Dry or Itchy Skin&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171840</classIRI>
<classLabel>Talquetamab</classLabel>
<deletedAxiom>&apos;Talquetamab&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Talquetamab&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132256</classIRI>
<classLabel>Unspecified Tissue</classLabel>
<deletedAxiom>&apos;Unspecified Tissue&apos; SubClassOf &apos;Tissue&apos;</deletedAxiom>
<newAxiom>&apos;Unspecified Tissue&apos; SubClassOf &apos;Tissue Sample&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132199</classIRI>
<classLabel>Past Seven Days Frequency of Urinary Incontinence</classLabel>
<newAxiom>&apos;Past Seven Days Frequency of Urinary Incontinence&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178809</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75563</classIRI>
<classLabel>Unemployment</classLabel>
<deletedAxiom>&apos;Unemployment&apos; SubClassOf &apos;Employment&apos;</deletedAxiom>
<newAxiom>&apos;Unemployment&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179143</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171210</classIRI>
<classLabel>Genetic Predisposition to Malignant Neoplasm</classLabel>
<deletedAxiom>&apos;Genetic Predisposition to Malignant Neoplasm&apos; SubClassOf &apos;Genetic Predisposition to Cancer&apos;</deletedAxiom>
<newAxiom>&apos;Genetic Predisposition to Malignant Neoplasm&apos; SubClassOf &apos;Genetic Predisposition to Tumor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75622</classIRI>
<classLabel>KCNQ1 Gene</classLabel>
<newAxiom>&apos;KCNQ1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Voltage-Gated Potassium Ion Channel Activation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75624</classIRI>
<classLabel>Potassium Voltage-Gated Channel Subfamily KQT Member 1</classLabel>
<deletedAxiom>&apos;Potassium Voltage-Gated Channel Subfamily KQT Member 1&apos; EquivalentTo &apos;Ion Channel Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Gastric Acid Secretion Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Gated Ion Channel&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Endosome&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Neuronal Transmission&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cardiac Muscle Contraction&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;KCNQ1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Potassium Voltage-Gated Channel Subfamily KQT Member 1&apos; EquivalentTo &apos;Ion Channel Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Gastric Acid Secretion Pathway&apos;) and (&apos;Gene_Product_Has_Organism_Source&apos; some &apos;Human&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Gated Ion Channel&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Endosome&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Neuronal Transmission&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cardiac Muscle Contraction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Voltage-Gated Potassium Ion Channel Activation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;KCNQ1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36081</classIRI>
<classLabel>Diffuse Large B-Cell Lymphoma Activated B-Cell Type</classLabel>
<deletedAxiom>&apos;Diffuse Large B-Cell Lymphoma Activated B-Cell Type&apos; EquivalentTo &apos;Diffuse Large B-Cell Lymphoma, Not Otherwise Specified by Gene Expression Profile&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (((&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic B-Immunoblast&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Immunoblastic Lymphoma&apos;)) or ((&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Centroblast&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Centroblastic Lymphoma&apos;))) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Activated B-Lymphocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;PKCbeta1 Messenger RNA Overexpression&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Cyclin D2 Messenger RNA Overexpression&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;BCL2 Gene mRNA Overexpression&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;IRF4/MUM1 Messenger RNA Overexpression&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;CD44 Messenger RNA Overexpression&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Increased NFkappaB Pathway Activation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;)</deletedAxiom>
<newAxiom>&apos;Diffuse Large B-Cell Lymphoma Activated B-Cell Type&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178541 and &apos;Diffuse Large B-Cell Lymphoma, Not Otherwise Specified by Gene Expression Profile&apos; and (((&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic B-Immunoblast&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Immunoblastic Lymphoma&apos;)) or ((&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Centroblast&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Centroblastic Lymphoma&apos;))) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Activated B-Lymphocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;PKCbeta1 Messenger RNA Overexpression&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Cyclin D2 Messenger RNA Overexpression&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;BCL2 Gene mRNA Overexpression&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;IRF4/MUM1 Messenger RNA Overexpression&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;CD44 Messenger RNA Overexpression&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Increased NFkappaB Pathway Activation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171051</classIRI>
<classLabel>FGF23 Overexpression Positive</classLabel>
<deletedAxiom>&apos;FGF23 Overexpression Positive&apos; SubClassOf &apos;Elevated Expression&apos;</deletedAxiom>
<deletedAxiom>&apos;FGF23 Overexpression Positive&apos; SubClassOf &apos;Positive Laboratory Test Result&apos;</deletedAxiom>
<newAxiom>&apos;FGF23 Overexpression Positive&apos; SubClassOf &apos;Growth Factor Overexpression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36394</classIRI>
<classLabel>t(9;15)(q22;q21)</classLabel>
<deletedAxiom>&apos;t(9;15)(q22;q21)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<deletedAxiom>&apos;t(9;15)(q22;q21)&apos; SubClassOf &apos;Molecular_Abnormality_Involves_Gene&apos; some &apos;NR4A3 Gene&apos;</deletedAxiom>
<newAxiom>&apos;t(9;15)(q22;q21)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178431</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36393</classIRI>
<classLabel>t(9;17)(q22;q11)</classLabel>
<deletedAxiom>&apos;t(9;17)(q22;q11)&apos; SubClassOf &apos;Molecular_Abnormality_Involves_Gene&apos; some &apos;NR4A3 Gene&apos;</deletedAxiom>
<deletedAxiom>&apos;t(9;17)(q22;q11)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<newAxiom>&apos;t(9;17)(q22;q11)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178431</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113453</classIRI>
<classLabel>Gaining Weight</classLabel>
<newAxiom>&apos;Gaining Weight&apos; SubClassOf &apos;Have Symptom or Condition Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95840</classIRI>
<classLabel>G Protein-Activated Inward Rectifier Potassium Channel 4</classLabel>
<deletedAxiom>&apos;G Protein-Activated Inward Rectifier Potassium Channel 4&apos; EquivalentTo &apos;Ion Channel Protein&apos; and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Heart&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Long QT Syndrome&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Exocrine Pancreas&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Neuronal Transmission&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;KCNJ5 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;G Protein-Activated Inward Rectifier Potassium Channel 4&apos; EquivalentTo &apos;Ion Channel Protein&apos; and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Transmembrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Heart&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Malfunction_Associated_With_Disease&apos; some &apos;Long QT Syndrome&apos;) and (&apos;Gene_Product_Expressed_In_Tissue&apos; some &apos;Exocrine Pancreas&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Neuronal Transmission&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Ion Transport Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Voltage-Gated Potassium Ion Channel Activation&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;KCNJ5 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95838</classIRI>
<classLabel>KCNJ5 Gene</classLabel>
<newAxiom>&apos;KCNJ5 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Voltage-Gated Potassium Ion Channel Activation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4264</classIRI>
<classLabel>Clear Cell Sarcoma of the Kidney</classLabel>
<deletedAxiom>&apos;Clear Cell Sarcoma of the Kidney&apos; EquivalentTo &apos;Childhood Malignant Kidney Neoplasm&apos; and &apos;Kidney Sarcoma&apos; and &apos;Childhood Soft Tissue Sarcoma&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Renal Medulla&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Fibrovascular Septa Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Cord-Like Pattern&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Epithelioid Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Spindle Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(10;17)(q22;p13)&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BCOR Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;YWHAE/FAM22 Fusion Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;YWHAE-FAM22 Fusion Protein Expression&apos;)</deletedAxiom>
<newAxiom>&apos;Clear Cell Sarcoma of the Kidney&apos; EquivalentTo &apos;Childhood Malignant Kidney Neoplasm&apos; and &apos;Kidney Sarcoma&apos; and &apos;Childhood Soft Tissue Sarcoma&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Renal Medulla&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Fibrovascular Septa Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Cord-Like Pattern&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Epithelioid Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Spindle Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(10;17)(q22;p13)&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BCOR Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;YWHAE/FAM22 Fusion Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;YWHAE-FAM22 Fusion Protein Expression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;BCOR Final Exon Internal Tandem Duplication&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170807</classIRI>
<classLabel>Advanced Endometrioid Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Advanced Endometrioid Adenocarcinoma&apos; EquivalentTo &apos;Advanced Adenocarcinoma&apos; and &apos;Advanced Genitourinary System Carcinoma&apos; and &apos;Advanced Malignant Female Reproductive System Neoplasm&apos; and &apos;Metastatic Endometrioid Adenocarcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Endometrioid Adenocarcinoma&apos; EquivalentTo &apos;Advanced Adenocarcinoma&apos; and &apos;Metastatic Endometrioid Adenocarcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170848</classIRI>
<classLabel>Bothered by Itching</classLabel>
<newAxiom>&apos;Bothered by Itching&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131340</classIRI>
<classLabel>Past Seven Days Frequency of Nosebleeds</classLabel>
<newAxiom>&apos;Past Seven Days Frequency of Nosebleeds&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179032</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131344</classIRI>
<classLabel>Worst Severity Past Seven Days Nosebleeds</classLabel>
<newAxiom>&apos;Worst Severity Past Seven Days Nosebleeds&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179032</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170955</classIRI>
<classLabel>Platinum-Resistant Malignant Germ Cell Tumor</classLabel>
<deletedAxiom>&apos;Platinum-Resistant Malignant Germ Cell Tumor&apos; EquivalentTo &apos;Malignant Germ Cell Tumor&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Platinum Resistance&apos;)</deletedAxiom>
<newAxiom>&apos;Platinum-Resistant Malignant Germ Cell Tumor&apos; EquivalentTo &apos;Refractory Malignant Germ Cell Tumor&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Platinum Resistance&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C106050</classIRI>
<classLabel>ChIP-On-Chip</classLabel>
<newAxiom>&apos;ChIP-On-Chip&apos; SubClassOf &apos;Chromatin Immunoprecipitation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4684</classIRI>
<classLabel>Nasal Type Extranodal NK/T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Nasal Type Extranodal NK/T-Cell Lymphoma&apos; EquivalentTo &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;CD56-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Normal_Cell_Origin&apos; some &apos;Cytotoxic T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Normal_Cell_Origin&apos; some &apos;Activated Natural Killer Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic T-Immunoblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Large T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Anaplastic Large T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Small T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(6q21q25)&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Diffuse Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;High Mitotic Activity&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemophagocytosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Malaise&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Polymorphic Cellular Infiltrate&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Coagulative Necrosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;EBV Infection&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Angiocentric Immunoproliferative Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Nasal Type Extranodal NK/T-Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178547 and &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;CD56-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Normal_Cell_Origin&apos; some &apos;Cytotoxic T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Normal_Cell_Origin&apos; some &apos;Activated Natural Killer Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic T-Immunoblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Large T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Anaplastic Large T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Small T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(6q21q25)&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Diffuse Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;High Mitotic Activity&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemophagocytosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Malaise&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Polymorphic Cellular Infiltrate&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Coagulative Necrosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;EBV Infection&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Angiocentric Immunoproliferative Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4337</classIRI>
<classLabel>Mantle Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Mantle Cell Lymphoma&apos; EquivalentTo &apos;Mature B-Cell Non-Hodgkin Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(11;14)(q13;q32)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal CCND1 Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CCND1 Protein Overexpression&apos;)) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Mantle Zone&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Peripheral B-Lymphocyte of Inner Mantle Zone&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Small to Medium-Sized B-Lymphocyte Resembling a Centrocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Heavy Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Trisomy 12&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(13q14)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 17p&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CCND1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Mantle Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178541 and &apos;Mature B-Cell Non-Hodgkin Lymphoma&apos; and ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(11;14)(q13;q32)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal CCND1 Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CCND1 Protein Overexpression&apos;)) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Mantle Zone&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Peripheral B-Lymphocyte of Inner Mantle Zone&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Small to Medium-Sized B-Lymphocyte Resembling a Centrocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Heavy Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Trisomy 12&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(13q14)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 17p&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;CCND1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4340</classIRI>
<classLabel>Peripheral T-Cell Lymphoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; EquivalentTo &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Peripheral (Post-Thymic) T-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Neoplastic Cells with TFH Cell Phenotype Present&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;)</deletedAxiom>
<newAxiom>&apos;Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178547 and &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Peripheral (Post-Thymic) T-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Neoplastic Cells with TFH Cell Phenotype Present&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4303</classIRI>
<classLabel>Myxoid Chondrosarcoma</classLabel>
<deletedAxiom>&apos;Myxoid Chondrosarcoma&apos; EquivalentTo &apos;Chondrosarcoma&apos; and &apos;FNCLCC Sarcoma Grade 2&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Myxoid Stroma Formation&apos;)</deletedAxiom>
<newAxiom>&apos;Myxoid Chondrosarcoma&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C37091</classIRI>
<classLabel>Vacuolated Endothelial Cell</classLabel>
<newAxiom>&apos;Vacuolated Endothelial Cell&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178561</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C37194</classIRI>
<classLabel>Anaplastic Large Cell Lymphoma, ALK-Negative</classLabel>
<deletedAxiom>&apos;Anaplastic Large Cell Lymphoma, ALK-Negative&apos; EquivalentTo &apos;Anaplastic Large Cell Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Activated Mature Cytotoxic T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Extranodal Disease&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;ALK Fusion Protein Expression&apos;)</deletedAxiom>
<newAxiom>&apos;Anaplastic Large Cell Lymphoma, ALK-Negative&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178547 and &apos;Anaplastic Large Cell Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Activated Mature Cytotoxic T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Extranodal Disease&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;ALK Fusion Protein Expression&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159663</classIRI>
<classLabel>Bladder Melanoma</classLabel>
<deletedAxiom>&apos;Bladder Melanoma&apos; EquivalentTo &apos;Mucosal Melanoma&apos; and &apos;Malignant Bladder Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bladder&apos;)</deletedAxiom>
<newAxiom>&apos;Bladder Melanoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178453 and &apos;Malignant Bladder Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bladder&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159665</classIRI>
<classLabel>Urethral Melanoma</classLabel>
<deletedAxiom>&apos;Urethral Melanoma&apos; EquivalentTo &apos;Mucosal Melanoma&apos; and &apos;Malignant Urethral Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Urethra&apos;)</deletedAxiom>
<newAxiom>&apos;Urethral Melanoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178453 and &apos;Malignant Urethral Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Urethra&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96402</classIRI>
<classLabel>Live Attenuated Influenza Vaccine</classLabel>
<newAxiom>&apos;Live Attenuated Influenza Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178427</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126662</classIRI>
<classLabel>Skin Itching at its Worst</classLabel>
<newAxiom>&apos;Skin Itching at its Worst&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165424</classIRI>
<classLabel>Does Skin in Treatment Area Itch</classLabel>
<newAxiom>&apos;Does Skin in Treatment Area Itch&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18251</classIRI>
<classLabel>EXT1 Gene</classLabel>
<deletedAxiom>&apos;EXT1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Multiple Osteochondromas&apos;</deletedAxiom>
<newAxiom>&apos;EXT1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Osteochondroma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18252</classIRI>
<classLabel>EXT2 Gene</classLabel>
<deletedAxiom>&apos;EXT2 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Multiple Osteochondromas&apos;</deletedAxiom>
<newAxiom>&apos;EXT2 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Osteochondroma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18260</classIRI>
<classLabel>TSC2 Gene</classLabel>
<deletedAxiom>&apos;TSC2 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Lymphangioleiomyomatosis&apos;</deletedAxiom>
<deletedAxiom>&apos;TSC2 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Lymphangioleiomyoma&apos;</deletedAxiom>
<newAxiom>&apos;TSC2 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;PEComa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18394</classIRI>
<classLabel>SMARCB1 Gene</classLabel>
<newAxiom>&apos;SMARCB1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178506</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5026</classIRI>
<classLabel>Recurrent Nasal Type Extranodal NK/T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Recurrent Nasal Type Extranodal NK/T-Cell Lymphoma&apos; EquivalentTo &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Nasal Type Extranodal NK/T-Cell Lymphoma&apos; and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Nasal Type Extranodal NK/T-Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178554 and &apos;Nasal Type Extranodal NK/T-Cell Lymphoma&apos; and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5008</classIRI>
<classLabel>Recurrent Burkitt Lymphoma</classLabel>
<deletedAxiom>&apos;Recurrent Burkitt Lymphoma&apos; EquivalentTo &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Recurrent Mature B-Cell Non-Hodgkin Lymphoma&apos; and &apos;Burkitt Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Burkitt Lymphoma&apos; EquivalentTo &apos;Recurrent Mature B-Cell Non-Hodgkin Lymphoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178553 and &apos;Burkitt Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131906</classIRI>
<classLabel>EBV-Positive Mucocutaneous Ulcer</classLabel>
<deletedAxiom>&apos;EBV-Positive Mucocutaneous Ulcer&apos; EquivalentTo &apos;EBV-Related Lymphoproliferative Disorder&apos; and &apos;Atypical Lymphoproliferative Disorder&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Skin&apos;) and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Mucosa&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;B-Lymphocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Skin Ulcer&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Immunodeficiency-Related Disorder&apos;)</deletedAxiom>
<newAxiom>&apos;EBV-Positive Mucocutaneous Ulcer&apos; EquivalentTo &apos;EBV-Related Lymphoproliferative Disorder&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179052 and &apos;Atypical Lymphoproliferative Disorder&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Skin&apos;) and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Mucosa&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Skin Ulcer&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Immunodeficiency-Related Disorder&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131911</classIRI>
<classLabel>Burkitt-Like Lymphoma with 11q Aberration</classLabel>
<deletedAxiom>&apos;Burkitt-Like Lymphoma with 11q Aberration&apos; EquivalentTo &apos;Mature B-Cell Non-Hodgkin Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized B-Lymphocyte with Basophilic Cytoplasm&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;11q Aberration&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;MYC Gene Amplification&apos;) and (&apos;Disease_Mapped_To_Chromosome&apos; some &apos;Chromosome 11&apos;)</deletedAxiom>
<newAxiom>&apos;Burkitt-Like Lymphoma with 11q Aberration&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178541 and &apos;Mature B-Cell Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized B-Lymphocyte with Basophilic Cytoplasm&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;11q Aberration&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;MYC Gene Amplification&apos;) and (&apos;Disease_Mapped_To_Chromosome&apos; some &apos;Chromosome 11&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131693</classIRI>
<classLabel>Have Dry or Itchy Skin</classLabel>
<newAxiom>&apos;Have Dry or Itchy Skin&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168700</classIRI>
<classLabel>Bothered by Genital Itching and/or Irritation</classLabel>
<newAxiom>&apos;Bothered by Genital Itching and/or Irritation&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7933</classIRI>
<classLabel>Grade III Lymphomatoid Granulomatosis</classLabel>
<deletedAxiom>&apos;Grade III Lymphomatoid Granulomatosis&apos; EquivalentTo &apos;EBV-Related Non-Hodgkin Lymphoma&apos; and &apos;Lymphomatoid Granulomatosis&apos; and &apos;Diffuse Large B-Cell Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Monomorphic Cellular Infiltrate&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Atypia&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 3&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic B-Immunoblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Hodgkin-Like Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fibrinoid Necrosis&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Heavy Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement&apos;)</deletedAxiom>
<newAxiom>&apos;Grade III Lymphomatoid Granulomatosis&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178541 and &apos;EBV-Related Non-Hodgkin Lymphoma&apos; and &apos;Lymphomatoid Granulomatosis&apos; and &apos;Diffuse Large B-Cell Lymphoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Monomorphic Cellular Infiltrate&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Atypia&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 3&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic B-Immunoblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Hodgkin-Like Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fibrinoid Necrosis&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Heavy Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168529</classIRI>
<classLabel>Elevated MET Protein Expression</classLabel>
<deletedAxiom>&apos;Elevated MET Protein Expression&apos; SubClassOf &apos;Elevated Expression&apos;</deletedAxiom>
<newAxiom>&apos;Elevated MET Protein Expression&apos; SubClassOf &apos;MET Overexpression Positive&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38150</classIRI>
<classLabel>PEComa</classLabel>
<deletedAxiom>&apos;PEComa&apos; EquivalentTo &apos;Soft Tissue Tumor of Uncertain Differentiation&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Perivascular Epithelioid Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;S-100-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Perivascular Arrangement of Tumor Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;HMB-45-Positive Neoplastic Cells Present&apos;)</deletedAxiom>
<newAxiom>&apos;PEComa&apos; EquivalentTo &apos;Soft Tissue Tumor of Uncertain Differentiation&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Perivascular Epithelioid Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;S-100-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Perivascular Arrangement of Tumor Cells&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;HMB-45-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;TFE3 Gene Rearrangement&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;TSC2 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TSC2 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38448</classIRI>
<classLabel>Lymphotoxin-Alpha Overexpression</classLabel>
<deletedAxiom>&apos;Lymphotoxin-Alpha Overexpression&apos; SubClassOf &apos;Elevated Expression&apos;</deletedAxiom>
<newAxiom>&apos;Lymphotoxin-Alpha Overexpression&apos; SubClassOf &apos;Growth Factor Overexpression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38450</classIRI>
<classLabel>Colony-Stimulating Factor Overexpression</classLabel>
<deletedAxiom>&apos;Colony-Stimulating Factor Overexpression&apos; SubClassOf &apos;Elevated Expression&apos;</deletedAxiom>
<newAxiom>&apos;Colony-Stimulating Factor Overexpression&apos; SubClassOf &apos;Growth Factor Overexpression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173926</classIRI>
<classLabel>Craniofacial Fibrous Dysplasia</classLabel>
<deletedAxiom>&apos;Craniofacial Fibrous Dysplasia&apos; SubClassOf &apos;Fibrous Dysplasia&apos;</deletedAxiom>
<newAxiom>&apos;Craniofacial Fibrous Dysplasia&apos; EquivalentTo &apos;Fibrous Dysplasia&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Skull&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101641</classIRI>
<classLabel>PALB2 Gene Mutation</classLabel>
<newAxiom>&apos;PALB2 Gene Mutation&apos; SubClassOf &apos;Gene_Mutant_Encodes_Gene_Product_Sequence_Variation&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178538</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97766</classIRI>
<classLabel>Sorting Nexin-29</classLabel>
<newAxiom>&apos;Sorting Nexin-29&apos; SubClassOf &apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Coiled-Coil Domain&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101443</classIRI>
<classLabel>H3-3A Gene</classLabel>
<newAxiom>&apos;H3-3A Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Giant Cell Tumor of Bone&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174484</classIRI>
<classLabel>t(9;22)(q22;q12)</classLabel>
<deletedAxiom>&apos;t(9;22)(q22;q12)&apos; SubClassOf &apos;Cytogenetic_Abnormality_Involves_Chromosome&apos; some &apos;Chromosome 9&apos;</deletedAxiom>
<deletedAxiom>&apos;t(9;22)(q22;q12)&apos; SubClassOf &apos;Molecular_Abnormality_Involves_Gene&apos; some &apos;NR4A3 Gene&apos;</deletedAxiom>
<newAxiom>&apos;t(9;22)(q22;q12)&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178431</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101573</classIRI>
<classLabel>SUMO-Activating Enzyme Subunit 1</classLabel>
<deletedAxiom>&apos;SUMO-Activating Enzyme Subunit 1&apos; EquivalentTo &apos;Ligase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Ubiquitin-mediated Proteolysis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Sumoylation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Endoplasmic Reticulum Degradation Pathway&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Post-Translational Modification&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;SAE1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;SUMO-Activating Enzyme Subunit 1&apos; EquivalentTo &apos;Ligase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Ubiquitin-mediated Proteolysis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Sumoylation Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Endoplasmic Reticulum Degradation Pathway&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178574) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Post-Translational Modification&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;SAE1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101570</classIRI>
<classLabel>SUMO-Activating Enzyme Subunit 2</classLabel>
<deletedAxiom>&apos;SUMO-Activating Enzyme Subunit 2&apos; EquivalentTo &apos;Ligase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Ubiquitin-mediated Proteolysis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Sumoylation Pathway&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Post-Translational Modification&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;UBA2 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;SUMO-Activating Enzyme Subunit 2&apos; EquivalentTo &apos;Ligase&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Ubiquitin-mediated Proteolysis Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Sumoylation Pathway&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178574) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Post-Translational Modification&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;UBA2 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8158</classIRI>
<classLabel>Recurrent Grade 3 Follicular Lymphoma</classLabel>
<deletedAxiom>&apos;Recurrent Grade 3 Follicular Lymphoma&apos; EquivalentTo &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Grade 3 Follicular Lymphoma&apos; and &apos;Recurrent Follicular Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Grade 3 Follicular Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178553 and &apos;Grade 3 Follicular Lymphoma&apos; and &apos;Recurrent Follicular Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174045</classIRI>
<classLabel>Locally Advanced Endometrioid Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Locally Advanced Endometrioid Adenocarcinoma&apos; EquivalentTo &apos;Locally Advanced Genitourinary System Carcinoma&apos; and &apos;Locally Advanced Adenocarcinoma&apos; and &apos;Locally Advanced Malignant Female Reproductive System Neoplasm&apos; and &apos;Metastatic Endometrioid Adenocarcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Locally Advanced Endometrioid Adenocarcinoma&apos; EquivalentTo &apos;Locally Advanced Adenocarcinoma&apos; and &apos;Metastatic Endometrioid Adenocarcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101094</classIRI>
<classLabel>Trivalent Live-Attenuated Influenza Vaccine</classLabel>
<deletedAxiom>&apos;Trivalent Live-Attenuated Influenza Vaccine&apos; SubClassOf &apos;Polyvalent Vaccine&apos;</deletedAxiom>
<newAxiom>&apos;Trivalent Live-Attenuated Influenza Vaccine&apos; SubClassOf &apos;Trivalent Influenza Vaccine&apos;</newAxiom>
<newAxiom>&apos;Trivalent Live-Attenuated Influenza Vaccine&apos; SubClassOf &apos;Live Attenuated Influenza Vaccine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101091</classIRI>
<classLabel>BCOR Gene</classLabel>
<newAxiom>&apos;BCOR Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178465</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115341</classIRI>
<classLabel>Most Food Tastes Unpleasant</classLabel>
<deletedAxiom>&apos;Most Food Tastes Unpleasant&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Most Food Tastes Unpleasant&apos; SubClassOf &apos;Taste Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8489</classIRI>
<classLabel>Recurrent Mantle Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Recurrent Mantle Cell Lymphoma&apos; EquivalentTo &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Recurrent Mature B-Cell Non-Hodgkin Lymphoma&apos; and &apos;Mantle Cell Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Mantle Cell Lymphoma&apos; EquivalentTo &apos;Recurrent Mature B-Cell Non-Hodgkin Lymphoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178553 and &apos;Mantle Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8459</classIRI>
<classLabel>Hepatosplenic T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Hepatosplenic T-Cell Lymphoma&apos; EquivalentTo &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and &apos;Liver Non-Hodgkin Lymphoma&apos; and &apos;Splenic Non-Hodgkin Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Marrow&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Peripheral (Post-Thymic) T-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized T-Lymphocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Sinusoidal Infiltration&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Bone Marrow Involvement&apos;) and (&apos;Disease_May_Have_Normal_Cell_Origin&apos; some &apos;Immature Peripheral Gamma/Delta Cell of Cytotoxic Type&apos;) and (&apos;Disease_May_Have_Normal_Cell_Origin&apos; some &apos;Immature Peripheral Alpha/Beta Cell of Cytotoxic Type&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Trisomy 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;i(7q)&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Thrombocytopenia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Leukocytosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;CD56-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Anemia&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;CD4-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;CD8-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;)</deletedAxiom>
<newAxiom>&apos;Hepatosplenic T-Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178547 and &apos;Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos; and &apos;Liver Non-Hodgkin Lymphoma&apos; and &apos;Splenic Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Marrow&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Peripheral (Post-Thymic) T-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized T-Lymphocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Sinusoidal Infiltration&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Bone Marrow Involvement&apos;) and (&apos;Disease_May_Have_Normal_Cell_Origin&apos; some &apos;Immature Peripheral Gamma/Delta Cell of Cytotoxic Type&apos;) and (&apos;Disease_May_Have_Normal_Cell_Origin&apos; some &apos;Immature Peripheral Alpha/Beta Cell of Cytotoxic Type&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Trisomy 8&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;i(7q)&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Thrombocytopenia&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Leukocytosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;CD56-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Anemia&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;CD4-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;CD8-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129797</classIRI>
<classLabel>Degree of Urinary Incontinence</classLabel>
<newAxiom>&apos;Degree of Urinary Incontinence&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178809</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8251</classIRI>
<classLabel>Recurrent Adult T-Cell Leukemia/Lymphoma</classLabel>
<deletedAxiom>&apos;Recurrent Adult T-Cell Leukemia/Lymphoma&apos; EquivalentTo &apos;Adult T-Cell Leukemia/Lymphoma&apos; and &apos;Recurrent Aggressive Adult Non-Hodgkin Lymphoma&apos; and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Adult T-Cell Leukemia/Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178554 and &apos;Adult T-Cell Leukemia/Lymphoma&apos; and &apos;Recurrent Aggressive Adult Non-Hodgkin Lymphoma&apos; and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8943</classIRI>
<classLabel>Metastatic Endometrioid Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Metastatic Endometrioid Adenocarcinoma&apos; EquivalentTo &apos;Metastatic Genitourinary System Carcinoma&apos; and &apos;Metastatic Malignant Female Reproductive System Neoplasm&apos; and &apos;Endometrioid Adenocarcinoma&apos; and &apos;Metastatic Adenocarcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Metastatic Endometrioid Adenocarcinoma&apos; EquivalentTo &apos;Endometrioid Adenocarcinoma&apos; and &apos;Metastatic Adenocarcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19837</classIRI>
<classLabel>hSWI/SNF Complex</classLabel>
<deletedAxiom>&apos;hSWI/SNF Complex&apos; SubClassOf &apos;Protein or Riboprotein Complex&apos;</deletedAxiom>
<newAxiom>&apos;hSWI/SNF Complex&apos; SubClassOf &apos;SWI/SNF Family Complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19878</classIRI>
<classLabel>SMARCA4 Gene</classLabel>
<deletedAxiom>&apos;SMARCA4 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Rhabdoid Tumor&apos;</deletedAxiom>
<newAxiom>&apos;SMARCA4 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Atypical Teratoid/Rhabdoid Tumor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8847</classIRI>
<classLabel>Refractory Burkitt Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory Burkitt Lymphoma&apos; EquivalentTo &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Burkitt Lymphoma&apos; and &apos;Refractory Mature B-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Burkitt Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178555 and &apos;Burkitt Lymphoma&apos; and &apos;Refractory Mature B-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8868</classIRI>
<classLabel>B Lymphoblastic Lymphoma</classLabel>
<deletedAxiom>&apos;B Lymphoblastic Lymphoma&apos; EquivalentTo &apos;B-Cell Non-Hodgkin Lymphoma&apos; and &apos;B Lymphoblastic Leukemia/Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Lymphoblastic Lymphoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Nodule&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphoblasts 25 Percent or Less of Bone Marrow Nucleated Cells&apos;)</deletedAxiom>
<newAxiom>&apos;B Lymphoblastic Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178541 and &apos;B Lymphoblastic Leukemia/Lymphoma&apos; and &apos;Lymphoblastic Lymphoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Nodule&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphoblasts 25 Percent or Less of Bone Marrow Nucleated Cells&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8869</classIRI>
<classLabel>Recurrent B Lymphoblastic Lymphoma</classLabel>
<deletedAxiom>&apos;Recurrent B Lymphoblastic Lymphoma&apos; EquivalentTo &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Recurrent B-Cell Non-Hodgkin Lymphoma&apos; and &apos;B Lymphoblastic Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent B Lymphoblastic Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178553 and &apos;B Lymphoblastic Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8870</classIRI>
<classLabel>Refractory B Lymphoblastic Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory B Lymphoblastic Lymphoma&apos; EquivalentTo &apos;Refractory Lymphoblastic Lymphoma&apos; and &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Refractory B-Cell Non-Hodgkin Lymphoma&apos; and &apos;B Lymphoblastic Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory B Lymphoblastic Lymphoma&apos; EquivalentTo &apos;Refractory Lymphoblastic Lymphoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178555 and &apos;B Lymphoblastic Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C154333</classIRI>
<classLabel>Recurrent Peripheral T-Cell Lymphoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Recurrent Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; EquivalentTo &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178554 and &apos;Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8862</classIRI>
<classLabel>Refractory Mantle Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory Mantle Cell Lymphoma&apos; EquivalentTo &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Mantle Cell Lymphoma&apos; and &apos;Refractory Mature B-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Mantle Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178555 and &apos;Mantle Cell Lymphoma&apos; and &apos;Refractory Mature B-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8715</classIRI>
<classLabel>Rhabdoid Tumor of the Kidney</classLabel>
<deletedAxiom>&apos;Rhabdoid Tumor of the Kidney&apos; EquivalentTo &apos;Childhood Malignant Kidney Neoplasm&apos; and &apos;Rhabdoid Tumor&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Kidney&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;SMARCB1 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 22&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Loss of INI 1 Protein Expression&apos;)</deletedAxiom>
<newAxiom>&apos;Rhabdoid Tumor of the Kidney&apos; EquivalentTo &apos;Childhood Malignant Kidney Neoplasm&apos; and &apos;Rhabdoid Tumor&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Kidney&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8680</classIRI>
<classLabel>Recurrent Enteropathy-Associated T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Recurrent Enteropathy-Associated T-Cell Lymphoma&apos; EquivalentTo &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Enteropathy-Associated T-Cell Lymphoma&apos; and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Enteropathy-Associated T-Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178554 and &apos;Enteropathy-Associated T-Cell Lymphoma&apos; and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8681</classIRI>
<classLabel>Refractory Enteropathy-Associated T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory Enteropathy-Associated T-Cell Lymphoma&apos; EquivalentTo &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Enteropathy-Associated T-Cell Lymphoma&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Enteropathy-Associated T-Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178556 and &apos;Enteropathy-Associated T-Cell Lymphoma&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8669</classIRI>
<classLabel>Refractory Nasal Type Extranodal NK/T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory Nasal Type Extranodal NK/T-Cell Lymphoma&apos; EquivalentTo &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Nasal Type Extranodal NK/T-Cell Lymphoma&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Nasal Type Extranodal NK/T-Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178556 and &apos;Nasal Type Extranodal NK/T-Cell Lymphoma&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8676</classIRI>
<classLabel>Recurrent Angioimmunoblastic T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Recurrent Angioimmunoblastic T-Cell Lymphoma&apos; EquivalentTo &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Angioimmunoblastic T-Cell Lymphoma&apos; and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Angioimmunoblastic T-Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178554 and &apos;Angioimmunoblastic T-Cell Lymphoma&apos; and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8671</classIRI>
<classLabel>Refractory Angioimmunoblastic T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory Angioimmunoblastic T-Cell Lymphoma&apos; EquivalentTo &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Angioimmunoblastic T-Cell Lymphoma&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Angioimmunoblastic T-Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178556 and &apos;Angioimmunoblastic T-Cell Lymphoma&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8657</classIRI>
<classLabel>Refractory Adult T-Cell Leukemia/Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory Adult T-Cell Leukemia/Lymphoma&apos; EquivalentTo &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Adult T-Cell Leukemia/Lymphoma&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Adult T-Cell Leukemia/Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178556 and &apos;Adult T-Cell Leukemia/Lymphoma&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6586</classIRI>
<classLabel>Extrarenal Rhabdoid Tumor</classLabel>
<deletedAxiom>&apos;Extrarenal Rhabdoid Tumor&apos; EquivalentTo &apos;Rhabdoid Tumor&apos; and &apos;Childhood Malignant Neoplasm&apos; and &apos;Malignant Soft Tissue Tumor of Uncertain Differentiation&apos; and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 22&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Loss of INI 1 Protein Expression&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Kidney&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Brain&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;SMARCB1 Gene Inactivation&apos;)</deletedAxiom>
<newAxiom>&apos;Extrarenal Rhabdoid Tumor&apos; EquivalentTo &apos;Rhabdoid Tumor&apos; and &apos;Childhood Malignant Neoplasm&apos; and &apos;Malignant Soft Tissue Tumor of Uncertain Differentiation&apos; and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Kidney&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Brain&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6474</classIRI>
<classLabel>Low Grade Central Osteosarcoma</classLabel>
<deletedAxiom>&apos;Low Grade Central Osteosarcoma&apos; EquivalentTo &apos;Primary Bone Osteosarcoma&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Medullary Bone&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Spindle-Shaped Osteoblast&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Osteoid Formation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Intraosseous Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Low Grade&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pathologic Fracture&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pain&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;MDM2 Gene Amplification&apos;)</deletedAxiom>
<newAxiom>&apos;Low Grade Central Osteosarcoma&apos; EquivalentTo &apos;Primary Bone Osteosarcoma&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Medullary Bone&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Spindle-Shaped Osteoblast&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Osteoid Formation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Intraosseous Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Low Grade&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pathologic Fracture&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pain&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CDK4 Gene Amplification&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;MDM2 Gene Amplification&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6472</classIRI>
<classLabel>Asynchronous Multifocal Osteosarcoma</classLabel>
<deletedAxiom>&apos;Asynchronous Multifocal Osteosarcoma&apos; SubClassOf &apos;Multifocal Osteosarcoma&apos;</deletedAxiom>
<newAxiom>&apos;Asynchronous Multifocal Osteosarcoma&apos; EquivalentTo &apos;Multifocal Osteosarcoma&apos; and (&apos;Disease_Excludes_Finding&apos; some &apos;Synchronous Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C64345</classIRI>
<classLabel>Cognitive Behavior Therapy</classLabel>
<newAxiom>&apos;Cognitive Behavior Therapy&apos; SubClassOf &apos;Behavioral Intervention&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172984</classIRI>
<classLabel>Bothered by Vaginal Bleeding or Spotting</classLabel>
<newAxiom>&apos;Bothered by Vaginal Bleeding or Spotting&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179032</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39591</classIRI>
<classLabel>Chronic Lymphoproliferative Disorder of NK-Cells</classLabel>
<deletedAxiom>&apos;Chronic Lymphoproliferative Disorder of NK-Cells&apos; EquivalentTo &apos;Mature T-Cell and NK-Cell Neoplasm&apos; and &apos;Benign Lymphoproliferative Disorder&apos; and (&apos;Disease_Has_Associated_Anatomic_Site&apos; some &apos;Lymphatic System&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Lymphoid Tissue&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Natural Killer Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Abnormal Large Granular Lymphocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Indolent Clinical Course&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Vasculitis&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Nephrotic Syndrome&apos;)</deletedAxiom>
<newAxiom>&apos;Chronic Lymphoproliferative Disorder of NK-Cells&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179053 and &apos;Mature T-Cell and NK-Cell Neoplasm&apos; and &apos;Benign Lymphoproliferative Disorder&apos; and (&apos;Disease_Has_Associated_Anatomic_Site&apos; some &apos;Lymphatic System&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Lymphoid Tissue&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Natural Killer Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Abnormal Large Granular Lymphocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Indolent Clinical Course&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Vasculitis&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Nephrotic Syndrome&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6906</classIRI>
<classLabel>Atypical Teratoid/Rhabdoid Tumor</classLabel>
<deletedAxiom>&apos;Atypical Teratoid/Rhabdoid Tumor&apos; EquivalentTo &apos;Rhabdoid Tumor&apos; and &apos;Central Nervous System Embryonal Neoplasm&apos; and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 22&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Loss of INI 1 Protein Expression&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Loss of BRG1 Protein Expression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;SMARCB1 Gene Inactivation&apos;)</deletedAxiom>
<newAxiom>&apos;Atypical Teratoid/Rhabdoid Tumor&apos; EquivalentTo &apos;Rhabdoid Tumor&apos; and &apos;Central Nervous System Embryonal Neoplasm&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Loss of BRG1 Protein Expression&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;SMARCA4 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;SMARCA4 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6902</classIRI>
<classLabel>Chondroid Chordoma</classLabel>
<deletedAxiom>&apos;Chondroid Chordoma&apos; EquivalentTo &apos;Chordoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Cartilage-Like Elements Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;High Grade Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Chondroid Chordoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178563 and (&apos;Disease_Has_Finding&apos; some &apos;Cartilage-Like Elements Present&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;High Grade Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6919</classIRI>
<classLabel>T Lymphoblastic Lymphoma</classLabel>
<deletedAxiom>&apos;T Lymphoblastic Lymphoma&apos; EquivalentTo &apos;T-Cell Non-Hodgkin Lymphoma&apos; and &apos;T Lymphoblastic Leukemia/Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Lymphoblastic Lymphoma&apos; and ((&apos;Disease_May_Have_Finding&apos; some &apos;Starry Sky Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;)) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Nodule&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphoblasts 25 Percent or Less of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;NOTCH1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;T Lymphoblastic Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178547 and &apos;T Lymphoblastic Leukemia/Lymphoma&apos; and &apos;Lymphoblastic Lymphoma&apos; and ((&apos;Disease_May_Have_Finding&apos; some &apos;Starry Sky Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;)) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Nodule&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphoblasts 25 Percent or Less of Bone Marrow Nucleated Cells&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;NOTCH1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25172</classIRI>
<classLabel>Employment</classLabel>
<deletedAxiom>&apos;Employment&apos; SubClassOf &apos;Personal Attribute&apos;</deletedAxiom>
<newAxiom>&apos;Employment&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179143</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172314</classIRI>
<classLabel>Refractory Grade 3 Follicular Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory Grade 3 Follicular Lymphoma&apos; EquivalentTo &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Grade 3 Follicular Lymphoma&apos; and &apos;Refractory Follicular Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Grade 3 Follicular Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178555 and &apos;Grade 3 Follicular Lymphoma&apos; and &apos;Refractory Follicular Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84070</classIRI>
<classLabel>Poloxamer 331</classLabel>
<newAxiom>&apos;Poloxamer 331&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178536</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84071</classIRI>
<classLabel>Poloxamer 407</classLabel>
<newAxiom>&apos;Poloxamer 407&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178536</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45194</classIRI>
<classLabel>Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type</classLabel>
<deletedAxiom>&apos;Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; EquivalentTo &apos;Primary Cutaneous Diffuse Large B-Cell Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;BCL2 Gene mRNA Overexpression&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;IRF4/MUM1 Messenger RNA Overexpression&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Confluent Sheets of Neoplastic B-Lymphocytes Present&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic B-Immunoblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Centroblast&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Rapidly Enlarging Mass&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Extracutaneous Dissemination of Disease&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Diffuse Large B-Cell Lymphoma Activated B-Cell Type&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(14;18)(q32;q21)&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178541 and &apos;Primary Cutaneous Diffuse Large B-Cell Lymphoma&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;BCL2 Gene mRNA Overexpression&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;IRF4/MUM1 Messenger RNA Overexpression&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Confluent Sheets of Neoplastic B-Lymphocytes Present&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic B-Immunoblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Centroblast&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Rapidly Enlarging Mass&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Extracutaneous Dissemination of Disease&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Diffuse Large B-Cell Lymphoma Activated B-Cell Type&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;t(14;18)(q32;q21)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84861</classIRI>
<classLabel>dHER2 Vaccine+AS15 Adjuvant</classLabel>
<deletedAxiom>&apos;dHER2 Vaccine+AS15 Adjuvant&apos; SubClassOf &apos;Agent Combination Indexed in Open Clinical Trials&apos;</deletedAxiom>
<newAxiom>&apos;dHER2 Vaccine+AS15 Adjuvant&apos; SubClassOf &apos;Peptide Vaccine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45231</classIRI>
<classLabel>Diffuse Large B-Cell Lymphoma Unclassifiable</classLabel>
<deletedAxiom>&apos;Diffuse Large B-Cell Lymphoma Unclassifiable&apos; EquivalentTo &apos;Diffuse Large B-Cell Lymphoma, Not Otherwise Specified by Gene Expression Profile&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (((&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic B-Immunoblast&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Immunoblastic Lymphoma&apos;)) or ((&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Centroblast&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Centroblastic Lymphoma&apos;))) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Cyclin D2 Messenger RNA Overexpression&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;IRF4/MUM1 Messenger RNA Overexpression&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCL2 Gene Translocation&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;REL Gene Amplification&apos;)</deletedAxiom>
<newAxiom>&apos;Diffuse Large B-Cell Lymphoma Unclassifiable&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178541 and &apos;Diffuse Large B-Cell Lymphoma, Not Otherwise Specified by Gene Expression Profile&apos; and (((&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic B-Immunoblast&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Immunoblastic Lymphoma&apos;)) or ((&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Centroblast&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Centroblastic Lymphoma&apos;))) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Cyclin D2 Messenger RNA Overexpression&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;IRF4/MUM1 Messenger RNA Overexpression&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;BCL2 Gene Translocation&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;REL Gene Amplification&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45339</classIRI>
<classLabel>Primary Cutaneous CD8-Positive Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Primary Cutaneous CD8-Positive Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma&apos; EquivalentTo &apos;Primary Cutaneous Peripheral T-Cell Lymphoma, Rare Subtype&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Cytotoxic T-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Nuclear Pleomorphism&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Epidermotropic Lymphocytic Infiltrate&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;CD8-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Small to Medium-Sized T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized to Large T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Nodule&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Angiocentric Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Angioinvasion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Patch&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Plaque&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Extracutaneous Dissemination of Disease&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Localized Skin Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Papular Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Multiple Tumor Masses&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Cutaneous CD8-Positive Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178547 and &apos;Primary Cutaneous Peripheral T-Cell Lymphoma, Rare Subtype&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Cytotoxic T-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Nuclear Pleomorphism&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Epidermotropic Lymphocytic Infiltrate&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;CD8-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Small to Medium-Sized T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized to Large T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Nodule&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Angiocentric Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Angioinvasion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Patch&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Plaque&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Extracutaneous Dissemination of Disease&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Localized Skin Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Papular Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Multiple Tumor Masses&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45340</classIRI>
<classLabel>Primary Cutaneous Gamma-Delta T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Primary Cutaneous Gamma-Delta T-Cell Lymphoma&apos; EquivalentTo &apos;Primary Cutaneous Peripheral T-Cell Lymphoma, Rare Subtype&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and ((&apos;Disease_May_Have_Finding&apos; some &apos;Subcutaneous Involvement&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Rimming of Adipose Tissue Cells Present&apos;)) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Activated Mature Gamma/Delta T-Lymphocyte with a Cytotoxic Phenotype&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized to Large T-Lymphocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Nodule&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Angioinvasion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Plaque&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Epidermotropic Lymphocytic Infiltrate&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;CD56-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Dermal Involvement&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;CD8-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Hemophagocytic Syndrome&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Cutaneous Gamma-Delta T-Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178547 and &apos;Primary Cutaneous Peripheral T-Cell Lymphoma, Rare Subtype&apos; and ((&apos;Disease_May_Have_Finding&apos; some &apos;Subcutaneous Involvement&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Rimming of Adipose Tissue Cells Present&apos;)) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Activated Mature Gamma/Delta T-Lymphocyte with a Cytotoxic Phenotype&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized to Large T-Lymphocyte&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Nodule&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Angioinvasion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Plaque&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Epidermotropic Lymphocytic Infiltrate&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;CD56-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Dermal Involvement&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;CD8-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Hemophagocytic Syndrome&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128820</classIRI>
<classLabel>EPCAM Gene Mutation</classLabel>
<newAxiom>&apos;EPCAM Gene Mutation&apos; SubClassOf &apos;Gene_Mutant_Encodes_Gene_Product_Sequence_Variation&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128825</classIRI>
<classLabel>STK11 Gene Mutation</classLabel>
<newAxiom>&apos;STK11 Gene Mutation&apos; SubClassOf &apos;Gene_Mutant_Encodes_Gene_Product_Sequence_Variation&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178533</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128823</classIRI>
<classLabel>PRSS1 Gene Mutation</classLabel>
<newAxiom>&apos;PRSS1 Gene Mutation&apos; SubClassOf &apos;Gene_Mutant_Encodes_Gene_Product_Sequence_Variation&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178535</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7238</classIRI>
<classLabel>Monomorphic T/NK-Cell Post-Transplant Lymphoproliferative Disorder</classLabel>
<deletedAxiom>&apos;Monomorphic T/NK-Cell Post-Transplant Lymphoproliferative Disorder&apos; EquivalentTo &apos;Monomorphic Post-Transplant Lymphoproliferative Disorder&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;CD30-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;)</deletedAxiom>
<newAxiom>&apos;Monomorphic T/NK-Cell Post-Transplant Lymphoproliferative Disorder&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179053 and &apos;Monomorphic Post-Transplant Lymphoproliferative Disorder&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;CD30-Positive Neoplastic Cells Present&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7246</classIRI>
<classLabel>Diffuse Large B-Cell Lymphoma Post-Transplant Lymphoproliferative Disorder</classLabel>
<deletedAxiom>&apos;Diffuse Large B-Cell Lymphoma Post-Transplant Lymphoproliferative Disorder&apos; EquivalentTo &apos;Monomorphic B-Cell Post-Transplant Lymphoproliferative Disorder&apos; and &apos;Diffuse Large B-Cell Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;)</deletedAxiom>
<newAxiom>&apos;Diffuse Large B-Cell Lymphoma Post-Transplant Lymphoproliferative Disorder&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178541 and &apos;Monomorphic B-Cell Post-Transplant Lymphoproliferative Disorder&apos; and &apos;Diffuse Large B-Cell Lymphoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7227</classIRI>
<classLabel>Refractory T Lymphoblastic Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory T Lymphoblastic Lymphoma&apos; EquivalentTo &apos;Refractory Lymphoblastic Lymphoma&apos; and &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;T Lymphoblastic Lymphoma&apos; and &apos;Refractory T-Cell Non-Hodgkin Lymphoma&apos; and &apos;Refractory T Lymphoblastic Leukemia/Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory T Lymphoblastic Lymphoma&apos; EquivalentTo &apos;Refractory Lymphoblastic Lymphoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178556 and &apos;T Lymphoblastic Lymphoma&apos; and &apos;Refractory T Lymphoblastic Leukemia/Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7234</classIRI>
<classLabel>Non-Destructive Post-Transplant Lymphoproliferative Disorder</classLabel>
<deletedAxiom>&apos;Non-Destructive Post-Transplant Lymphoproliferative Disorder&apos; EquivalentTo &apos;Post-Transplant Lymphoproliferative Disorder&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Lymphoid Tissue&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;B-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Reactive Lymphocyte&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;EBV Infection&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Gene Rearrangement&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gene Rearrangement&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Architectural Distortion&apos;)</deletedAxiom>
<newAxiom>&apos;Non-Destructive Post-Transplant Lymphoproliferative Disorder&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179052 and &apos;Post-Transplant Lymphoproliferative Disorder&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Lymphoid Tissue&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Reactive Lymphocyte&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;EBV Infection&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Gene Rearrangement&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gene Rearrangement&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Architectural Distortion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7258</classIRI>
<classLabel>Nodular Lymphocyte Predominant Hodgkin Lymphoma</classLabel>
<deletedAxiom>&apos;Nodular Lymphocyte Predominant Hodgkin Lymphoma&apos; EquivalentTo &apos;Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Germinal Center B-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Popcorn Cell&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Heavy Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Warthin-Finkeldey Polykaryocyte&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Nodular Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Nodular and Diffuse Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Favorable Clinical Outcome&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Progressive Transformation of Germinal Centers&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;CD15-Positive Neoplastic Cells Present&apos;)</deletedAxiom>
<newAxiom>&apos;Nodular Lymphocyte Predominant Hodgkin Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179052 and &apos;Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Germinal Center B-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Popcorn Cell&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Heavy Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Warthin-Finkeldey Polykaryocyte&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Nodular Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Nodular and Diffuse Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Favorable Clinical Outcome&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Progressive Transformation of Germinal Centers&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;CD15-Positive Neoplastic Cells Present&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7212</classIRI>
<classLabel>AIDS-Related Diffuse Large B-cell Lymphoma</classLabel>
<deletedAxiom>&apos;AIDS-Related Diffuse Large B-cell Lymphoma&apos; EquivalentTo &apos;AIDS-Related Non-Hodgkin Lymphoma&apos; and &apos;Diffuse Large B-Cell Lymphoma&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;AIDS-Related Diffuse Large B-cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178541 and &apos;AIDS-Related Non-Hodgkin Lymphoma&apos; and &apos;Diffuse Large B-Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7155</classIRI>
<classLabel>Primary Central Chondrosarcoma</classLabel>
<deletedAxiom>&apos;Primary Central Chondrosarcoma&apos; EquivalentTo &apos;Chondrosarcoma&apos; and &apos;Bone Sarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Lobulated Growth Pattern&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 19&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 10p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(1p36)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(1p13-22)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 4&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(5q13-31)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(6q22-qter)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(9p22-pter)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(10q24-qter)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(11p13-pter)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(11q25)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(13q21-qter)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 18p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(22q13)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 7p13-pter&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 12q15-qter&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Swelling&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;High Mitotic Activity&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Myxoid Stroma Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cystic Change&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Bone Surface&apos;)</deletedAxiom>
<newAxiom>&apos;Primary Central Chondrosarcoma&apos; EquivalentTo &apos;Chondrosarcoma&apos; and &apos;Bone Sarcoma&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Medullary Bone&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Bone Surface&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Secondary Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7113</classIRI>
<classLabel>Endometrioid Tumor</classLabel>
<deletedAxiom>&apos;Endometrioid Tumor&apos; EquivalentTo &apos;Female Reproductive System Neoplasm&apos; and &apos;Epithelial Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Female Reproductive System&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Glandular Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Neoplastic Glandular Epithelium Resembling the Normal Endometrium Present&apos;)</deletedAxiom>
<newAxiom>&apos;Endometrioid Tumor&apos; EquivalentTo &apos;Epithelial Neoplasm&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Glandular Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Neoplastic Glandular Epithelium Resembling the Normal Endometrium Present&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7063</classIRI>
<classLabel>Notochordal Tumor</classLabel>
<deletedAxiom>&apos;Notochordal Tumor&apos; EquivalentTo &apos;Embryonal Neoplasm&apos; and &apos;Bone Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Remnants of the Notochord&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Physaliphorous Cell&apos;)</deletedAxiom>
<newAxiom>&apos;Notochordal Tumor&apos; EquivalentTo &apos;Embryonal Neoplasm&apos; and &apos;Bone Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Remnants of the Notochord&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128455</classIRI>
<classLabel>Quadrivalent Inactivated Influenza Vaccine</classLabel>
<newAxiom>&apos;Quadrivalent Inactivated Influenza Vaccine&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178427</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153579</classIRI>
<classLabel>Recurrent Appendix Mucinous Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Recurrent Appendix Mucinous Adenocarcinoma&apos; EquivalentTo &apos;Recurrent Appendix Carcinoma&apos; and &apos;Recurrent Adenocarcinoma&apos; and &apos;Appendix Mucinous Adenocarcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Appendix Mucinous Adenocarcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179174 and &apos;Appendix Mucinous Adenocarcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153358</classIRI>
<classLabel>Locally Advanced Digestive System Carcinoma</classLabel>
<deletedAxiom>&apos;Locally Advanced Digestive System Carcinoma&apos; EquivalentTo &apos;Metastatic Digestive System Carcinoma&apos; and &apos;Locally Advanced Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Locally Advanced Digestive System Carcinoma&apos; EquivalentTo &apos;Metastatic Digestive System Carcinoma&apos; and &apos;Locally Advanced Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179181</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7528</classIRI>
<classLabel>Angioimmunoblastic T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Angioimmunoblastic T-Cell Lymphoma&apos; EquivalentTo &apos;Nodal Peripheral T-Cell Lymphoma of T Follicular Helper Cell Origin&apos; and &apos;Aggressive Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;CD4-Positive T-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Small to Medium-Sized T-Lymphocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Neoplastic Cells with TFH Cell Phenotype Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Polymorphic Cellular Infiltrate&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Proliferation of High Endothelial Venules Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Proliferation of Follicular Dendritic Cells Present&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic T-Immunoblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Reed-Sternberg-Like Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte with Clear Cytoplasm&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Trisomy 3&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Trisomy 5&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome X&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Rash&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;EBV Infection&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;)</deletedAxiom>
<newAxiom>&apos;Angioimmunoblastic T-Cell Lymphoma&apos; EquivalentTo &apos;Nodal Peripheral T-Cell Lymphoma of T Follicular Helper Cell Origin&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178547 and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;CD4-Positive T-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Small to Medium-Sized T-Lymphocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Neoplastic Cells with TFH Cell Phenotype Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Polymorphic Cellular Infiltrate&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Proliferation of High Endothelial Venules Present&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Proliferation of Follicular Dendritic Cells Present&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic T-Immunoblast&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Reed-Sternberg-Like Cell&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized T-Lymphocyte&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte with Clear Cytoplasm&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Trisomy 3&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Trisomy 5&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome X&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hepatomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Splenomegaly&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Skin Rash&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lymphadenopathy&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;EBV Infection&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Beta Chain Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Clonal T-Cell Receptor Gamma Chain Gene Rearrangement&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7400</classIRI>
<classLabel>Burkitt Leukemia</classLabel>
<deletedAxiom>&apos;Burkitt Leukemia&apos; EquivalentTo &apos;Lymphoid Leukemia&apos; and &apos;Acute Leukemia&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Germinal Center B-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized B-Lymphocyte with Basophilic Cytoplasm&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Leukemic Medium-Sized B-Lymphocyte with Basophilic Cytoplasm&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Heavy Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;MYC Gene Amplification&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Bone Marrow and Blood Involvement&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(2;8)(p11;q24)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(8;14)(q24;q32)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(8;22)(q24;q11)&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MYC Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Burkitt Leukemia&apos; EquivalentTo &apos;Mature B-Cell Neoplasm&apos; and &apos;Lymphoid Leukemia&apos; and &apos;Acute Leukemia&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Germinal Center B-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Medium-Sized B-Lymphocyte with Basophilic Cytoplasm&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Leukemic Medium-Sized B-Lymphocyte with Basophilic Cytoplasm&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Heavy Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;MYC Gene Amplification&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Aggressive Clinical Course&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Bone Marrow and Blood Involvement&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(2;8)(p11;q24)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(8;14)(q24;q32)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(8;22)(q24;q11)&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MYC Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153160</classIRI>
<classLabel>Recurrent Hepatosplenic T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Recurrent Hepatosplenic T-Cell Lymphoma&apos; EquivalentTo &apos;Recurrent Primary Malignant Neoplasm&apos; and &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Hepatosplenic T-Cell Lymphoma&apos; and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Hepatosplenic T-Cell Lymphoma&apos; EquivalentTo &apos;Recurrent Primary Malignant Neoplasm&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178554 and &apos;Hepatosplenic T-Cell Lymphoma&apos; and &apos;Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153161</classIRI>
<classLabel>Refractory Hepatosplenic T-Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory Hepatosplenic T-Cell Lymphoma&apos; EquivalentTo &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Hepatosplenic T-Cell Lymphoma&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Hepatosplenic T-Cell Lymphoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178556 and &apos;Hepatosplenic T-Cell Lymphoma&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7357</classIRI>
<classLabel>Periosteal Chondrosarcoma</classLabel>
<deletedAxiom>&apos;Periosteal Chondrosarcoma&apos; EquivalentTo &apos;Chondrosarcoma&apos; and &apos;Bone Sarcoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Surface&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Pain&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lobulated Growth Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Swelling&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;High Mitotic Activity&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Myxoid Stroma Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cystic Change&apos;)</deletedAxiom>
<newAxiom>&apos;Periosteal Chondrosarcoma&apos; EquivalentTo &apos;Chondrosarcoma&apos; and &apos;Bone Sarcoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Surface&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Pain&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Lobulated Growth Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Swelling&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;High Mitotic Activity&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Myxoid Stroma Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cystic Change&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;IDH1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;IDH2 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99238</classIRI>
<classLabel>EWSR1/PATZ1 Fusion Gene</classLabel>
<deletedAxiom>&apos;EWSR1/PATZ1 Fusion Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor&apos;</deletedAxiom>
<newAxiom>&apos;EWSR1/PATZ1 Fusion Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178461</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122832</classIRI>
<classLabel>Vepoloxamer</classLabel>
<newAxiom>&apos;Vepoloxamer&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178536</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99249</classIRI>
<classLabel>EWSR1/CREB1 Fusion Gene</classLabel>
<newAxiom>&apos;EWSR1/CREB1 Fusion Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Clear Cell Sarcoma of Soft Tissue&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26492</classIRI>
<classLabel>RECQL4 Gene</classLabel>
<deletedAxiom>&apos;RECQL4 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Rothmund-Thomson Syndrome&apos;</deletedAxiom>
<newAxiom>&apos;RECQL4 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178827</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176681</classIRI>
<classLabel>Refractory Breast Implant-Associated Anaplastic Large Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Refractory Breast Implant-Associated Anaplastic Large Cell Lymphoma&apos; EquivalentTo &apos;Refractory Breast Lymphoma&apos; and &apos;Breast Implant-Associated Anaplastic Large Cell Lymphoma&apos; and &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Refractory Anaplastic Large Cell Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Breast Implant-Associated Anaplastic Large Cell Lymphoma&apos; EquivalentTo &apos;Refractory Breast Lymphoma&apos; and &apos;Breast Implant-Associated Anaplastic Large Cell Lymphoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178556 and &apos;Refractory Anaplastic Large Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176680</classIRI>
<classLabel>Recurrent Breast Implant-Associated Anaplastic Large Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Recurrent Breast Implant-Associated Anaplastic Large Cell Lymphoma&apos; EquivalentTo &apos;Recurrent Breast Lymphoma&apos; and &apos;Breast Implant-Associated Anaplastic Large Cell Lymphoma&apos; and &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Recurrent Anaplastic Large Cell Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Breast Implant-Associated Anaplastic Large Cell Lymphoma&apos; EquivalentTo &apos;Recurrent Breast Lymphoma&apos; and &apos;Breast Implant-Associated Anaplastic Large Cell Lymphoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178554 and &apos;Recurrent Anaplastic Large Cell Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C32352</classIRI>
<classLabel>Common Carotid Artery</classLabel>
<deletedAxiom>&apos;Common Carotid Artery&apos; SubClassOf &apos;Carotid Artery&apos;</deletedAxiom>
<newAxiom>&apos;Common Carotid Artery&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C32551</classIRI>
<classLabel>External Carotid Artery</classLabel>
<deletedAxiom>&apos;External Carotid Artery&apos; SubClassOf &apos;Carotid Artery&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C32836</classIRI>
<classLabel>Internal Carotid Artery</classLabel>
<deletedAxiom>&apos;Internal Carotid Artery&apos; SubClassOf &apos;Carotid Artery&apos;</deletedAxiom>
<newAxiom>&apos;Internal Carotid Artery&apos; SubClassOf &apos;Common Carotid Artery Branch&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C32956</classIRI>
<classLabel>Left Common Carotid Artery</classLabel>
<deletedAxiom>&apos;Left Common Carotid Artery&apos; SubClassOf &apos;Common Carotid Artery&apos;</deletedAxiom>
<newAxiom>&apos;Left Common Carotid Artery&apos; SubClassOf &apos;Carotid Artery&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121871</classIRI>
<classLabel>Grade III Chondrosarcoma</classLabel>
<deletedAxiom>&apos;Grade III Chondrosarcoma&apos; EquivalentTo &apos;Chondrosarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 3&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Low Grade Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Intermediate Grade Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Grade III Chondrosarcoma&apos; EquivalentTo &apos;Chondrosarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 3&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Low Grade Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Intermediate Grade Lesion&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;IDH1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;IDH2 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121870</classIRI>
<classLabel>Grade II Chondrosarcoma</classLabel>
<deletedAxiom>&apos;Grade II Chondrosarcoma&apos; EquivalentTo &apos;Chondrosarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Intermediate Grade Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 2&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Low Grade Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Grade II Chondrosarcoma&apos; EquivalentTo &apos;Chondrosarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Intermediate Grade Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 2&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Low Grade Lesion&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;IDH1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;IDH2 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121882</classIRI>
<classLabel>Secondary Peripheral Chondrosarcoma</classLabel>
<deletedAxiom>&apos;Secondary Peripheral Chondrosarcoma&apos; EquivalentTo &apos;Secondary Chondrosarcoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Surface&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Osteochondroma&apos;)</deletedAxiom>
<newAxiom>&apos;Secondary Peripheral Chondrosarcoma&apos; EquivalentTo &apos;Secondary Chondrosarcoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bone Surface&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Cartilaginous Tissue&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Osteochondroma&apos;) and (&apos;Disease_Excludes_Normal_Tissue_Origin&apos; some &apos;Medullary Bone&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66852</classIRI>
<classLabel>Carotid Body</classLabel>
<deletedAxiom>&apos;Carotid Body&apos; SubClassOf &apos;Anatomic_Structure_Has_Location&apos; some &apos;Common Carotid Artery&apos;</deletedAxiom>
<newAxiom>&apos;Carotid Body&apos; SubClassOf &apos;Anatomic_Structure_Has_Location&apos; some &apos;Carotid Artery&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27291</classIRI>
<classLabel>Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor</classLabel>
<deletedAxiom>&apos;Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor&apos; EquivalentTo &apos;Embryonal Neoplasm&apos; and (((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(11;22)(q24;q12)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-FLI1 Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(21;22)(q22;q12)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-ERG Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(7;22)(p22;q12)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-ETV1 Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(17;22)(q21;q12)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-ETV4 Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(16;21)(p11;q22)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;FUS-ERG Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(2;22)(q33;q12)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-FEV Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(1;22)(p36.1;q12)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;inv(22q12)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-PATZ1 Fusion Protein Expression&apos;))) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Neural Crest&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Primitive Round to Oval Cell&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;EWSR1 Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Small Round Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemorrhagic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Homer Wright Rosette Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Anemia&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;CIC Gene Rearrangement&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/FLI1 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/ERG Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/FEV Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/PATZ1 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/ETV1 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/ETV4 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;FUS/ERG Fusion Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor&apos; EquivalentTo &apos;Embryonal Neoplasm&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Neural Crest&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Primitive Round to Oval Cell&apos;) and (&apos;Disease_Has_Cytogenetic_Abnormality&apos; some &apos;EWSR1 Gene Rearrangement&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Malignant Small Round Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(11;22)(q24;q12)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(21;22)(q22;q12)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(7;22)(p22;q12)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(17;22)(q21;q12)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(16;21)(p11;q22)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(2;22)(q33;q12)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(1;22)(p36.1;q12)&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemorrhagic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Homer Wright Rosette Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Anemia&apos;) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178457) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178458) and (&apos;Disease_Excludes_Molecular_Abnormality&apos; some &apos;EWSR1-PATZ1 Fusion Protein Expression&apos;) and (&apos;Disease_Excludes_Cytogenetic_Abnormality&apos; some &apos;CIC Gene Rearrangement&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/FLI1 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/ERG Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/FEV Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/ETV1 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/ETV4 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;FUS/ERG Fusion Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-FLI1 Fusion Protein Expression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-ERG Fusion Protein Expression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-ETV1 Fusion Protein Expression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-ETV4 Fusion Protein Expression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-FEV Fusion Protein Expression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;FUS-ERG Fusion Protein Expression&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121932</classIRI>
<classLabel>Giant Cell Tumor of Bone</classLabel>
<deletedAxiom>&apos;Giant Cell Tumor of Bone&apos; EquivalentTo &apos;Intermediate Osteoclastic Giant Cell-Rich Tumor of Bone&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Mononuclear Stromal Cell&apos;)</deletedAxiom>
<newAxiom>&apos;Giant Cell Tumor of Bone&apos; EquivalentTo &apos;Intermediate Osteoclastic Giant Cell-Rich Tumor of Bone&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Mononuclear Stromal Cell&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;H3-3A Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;H3F3A Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121901</classIRI>
<classLabel>Benign Notochordal Cell Tumor</classLabel>
<deletedAxiom>&apos;Benign Notochordal Cell Tumor&apos; EquivalentTo &apos;Benign Bone Neoplasm&apos; and &apos;Notochordal Tumor&apos; and (&apos;Disease_Excludes_Finding&apos; some &apos;Lobulated Growth Pattern&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Myxoid Stroma Formation&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Atypia&apos;)</deletedAxiom>
<newAxiom>&apos;Benign Notochordal Cell Tumor&apos; EquivalentTo &apos;Benign Bone Neoplasm&apos; and &apos;Notochordal Tumor&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178561) and (&apos;Disease_Excludes_Finding&apos; some &apos;Lobulated Growth Pattern&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Myxoid Stroma Formation&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Atypia&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27394</classIRI>
<classLabel>Vaginal Melanoma</classLabel>
<deletedAxiom>&apos;Vaginal Melanoma&apos; EquivalentTo &apos;Mucosal Melanoma&apos; and &apos;Malignant Vaginal Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Female Reproductive System&apos;) and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Vagina&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NF2 Gene Inactivation&apos;)</deletedAxiom>
<newAxiom>&apos;Vaginal Melanoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178437 and &apos;Malignant Vaginal Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Vagina&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Vaginal Hemorrhage&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NF2 Gene Inactivation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27378</classIRI>
<classLabel>Adult Myxoid Chondrosarcoma</classLabel>
<deletedAxiom>&apos;Adult Myxoid Chondrosarcoma&apos; EquivalentTo &apos;Myxoid Chondrosarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Adulthood Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Adult Myxoid Chondrosarcoma&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27377</classIRI>
<classLabel>Childhood Myxoid Chondrosarcoma</classLabel>
<deletedAxiom>&apos;Childhood Myxoid Chondrosarcoma&apos; EquivalentTo &apos;Childhood Malignant Neoplasm&apos; and &apos;Myxoid Chondrosarcoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Chondrocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Childhood Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Childhood Myxoid Chondrosarcoma&apos; EquivalentTo &apos;Extraskeletal Myxoid Chondrosarcoma&apos; and &apos;Childhood Soft Tissue Sarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121761</classIRI>
<classLabel>Worst Severity Past Seven Days Itchy Skin</classLabel>
<newAxiom>&apos;Worst Severity Past Seven Days Itchy Skin&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27502</classIRI>
<classLabel>Extraskeletal Myxoid Chondrosarcoma</classLabel>
<deletedAxiom>&apos;Extraskeletal Myxoid Chondrosarcoma&apos; EquivalentTo &apos;Malignant Soft Tissue Tumor of Uncertain Differentiation&apos; and &apos;Soft Tissue Sarcoma&apos; and (((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(9;17)(q22;q11)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TAF15-NR4A3 Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(9;15)(q22;q21)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TCF12-NR4A3 Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(9;22)(q22-31;q12)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-NR4A3 Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(3;9)(q11-12;q22)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TFG-NR4A3 Fusion Protein Expression&apos;))) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Cell with Eosinophilic Cytoplasm&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Multinodular Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myxoid Stroma Formation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Extraosseous Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemorrhagic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cribriform Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cystic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cord-Like Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Spindle Cell Pattern&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/NR4A3 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;TCF12/NR4A3 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;TAF15/NR4A3 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;TFG/NR4A3 Fusion Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Extraskeletal Myxoid Chondrosarcoma&apos; EquivalentTo &apos;Malignant Soft Tissue Tumor of Uncertain Differentiation&apos; and &apos;Soft Tissue Sarcoma&apos; and (((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(9;17)(q22;q11)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TAF15-NR4A3 Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(9;15)(q22;q21)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TCF12-NR4A3 Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(9;22)(q22-31;q12)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;EWSR1-NR4A3 Fusion Protein Expression&apos;)) or ((&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;t(3;9)(q11-12;q22)&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TFG-NR4A3 Fusion Protein Expression&apos;))) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Cell with Eosinophilic Cytoplasm&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Multinodular Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Myxoid Stroma Formation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Extraosseous Lesion&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178431) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemorrhagic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cribriform Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cystic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cord-Like Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Spindle Cell Pattern&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;EWSR1/NR4A3 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;TCF12/NR4A3 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;TAF15/NR4A3 Fusion Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;TFG/NR4A3 Fusion Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27908</classIRI>
<classLabel>T-Cell and NK-Cell Neoplasm</classLabel>
<deletedAxiom>&apos;T-Cell and NK-Cell Neoplasm&apos; EquivalentTo &apos;Lymphocytic Neoplasm&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;T-Lymphocyte and Natural Killer Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Neoplastic B-Lymphocyte&apos;)</deletedAxiom>
<newAxiom>&apos;T-Cell and NK-Cell Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179053 and &apos;Lymphocytic Neoplasm&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Neoplastic B-Lymphocyte&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27907</classIRI>
<classLabel>B-Cell Neoplasm</classLabel>
<deletedAxiom>&apos;B-Cell Neoplasm&apos; EquivalentTo &apos;Lymphocytic Neoplasm&apos; and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;B-Lymphocyte&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic B-Lymphocyte&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell&apos;)</deletedAxiom>
<newAxiom>&apos;B-Cell Neoplasm&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179052 and &apos;Lymphocytic Neoplasm&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic B-Lymphocyte&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C169021</classIRI>
<classLabel>Platinum-Resistant Malignant Female Reproductive System Neoplasm</classLabel>
<deletedAxiom>&apos;Platinum-Resistant Malignant Female Reproductive System Neoplasm&apos; EquivalentTo &apos;Refractory Malignant Female Reproductive System Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Platinum Resistance&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Platinum Sensitivity&apos;)</deletedAxiom>
<newAxiom>&apos;Platinum-Resistant Malignant Female Reproductive System Neoplasm&apos; EquivalentTo &apos;Refractory Malignant Female Reproductive System Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Platinum Resistance&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160231</classIRI>
<classLabel>Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type</classLabel>
<deletedAxiom>&apos;Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type&apos; EquivalentTo &apos;Recurrent Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified&apos; and &apos;Diffuse Large B-Cell Lymphoma Activated B-Cell Type&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type&apos; EquivalentTo &apos;Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178553 and &apos;Diffuse Large B-Cell Lymphoma Activated B-Cell Type&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160239</classIRI>
<classLabel>Refractory Diffuse Large B-Cell Lymphoma Activated B-Cell Type</classLabel>
<deletedAxiom>&apos;Refractory Diffuse Large B-Cell Lymphoma Activated B-Cell Type&apos; EquivalentTo &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified&apos; and &apos;Diffuse Large B-Cell Lymphoma Activated B-Cell Type&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Diffuse Large B-Cell Lymphoma Activated B-Cell Type&apos; EquivalentTo &apos;Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178555 and &apos;Diffuse Large B-Cell Lymphoma Activated B-Cell Type&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9027</classIRI>
<classLabel>Grade I Chondrosarcoma</classLabel>
<deletedAxiom>&apos;Grade I Chondrosarcoma&apos; EquivalentTo &apos;Chondrosarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Low Grade Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Well Differentiated Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 1&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Intermediate Grade Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Grade I Chondrosarcoma&apos; EquivalentTo &apos;Chondrosarcoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Low Grade Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Well Differentiated Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 1&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Intermediate Grade Lesion&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;IDH1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;IDH2 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136358</classIRI>
<classLabel>How Much Bothered by Being Itchy</classLabel>
<deletedAxiom>&apos;How Much Bothered by Being Itchy&apos; SubClassOf &apos;Have Trouble or Difficulty Question&apos;</deletedAxiom>
<newAxiom>&apos;How Much Bothered by Being Itchy&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136357</classIRI>
<classLabel>How Itchy</classLabel>
<deletedAxiom>&apos;How Itchy&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;How Itchy&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136347</classIRI>
<classLabel>Were Itchy</classLabel>
<deletedAxiom>&apos;Were Itchy&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Were Itchy&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136355</classIRI>
<classLabel>How Much Time Itchy</classLabel>
<deletedAxiom>&apos;How Much Time Itchy&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;How Much Time Itchy&apos; SubClassOf &apos;Pruritus Questions&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9467</classIRI>
<classLabel>Chronic Cancer Pain</classLabel>
<newAxiom>&apos;Chronic Cancer Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178565</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9339</classIRI>
<classLabel>Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified</classLabel>
<deletedAxiom>&apos;Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; EquivalentTo &apos;Refractory Aggressive Non-Hodgkin Lymphoma&apos; and &apos;Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</deletedAxiom>
<newAxiom>&apos;Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178556 and &apos;Peripheral T-Cell Lymphoma, Not Otherwise Specified&apos; and &apos;Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C33473</classIRI>
<classLabel>Right Common Carotid Artery</classLabel>
<deletedAxiom>&apos;Right Common Carotid Artery&apos; SubClassOf &apos;Common Carotid Artery&apos;</deletedAxiom>
<newAxiom>&apos;Right Common Carotid Artery&apos; SubClassOf &apos;Carotid Artery&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116981</classIRI>
<classLabel>Have Problems with Sense of Taste or Smell</classLabel>
<newAxiom>&apos;Have Problems with Sense of Taste or Smell&apos; SubClassOf &apos;Taste Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175005</classIRI>
<classLabel>Age in Days at Laboratory Test</classLabel>
<deletedAxiom>&apos;Age in Days at Laboratory Test&apos; SubClassOf &apos;Age-Days&apos;</deletedAxiom>
<newAxiom>&apos;Age in Days at Laboratory Test&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116453</classIRI>
<classLabel>Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging</classLabel>
<deletedAxiom>&apos;Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging&apos; SubClassOf &apos;Magnetic Resonance Imaging&apos;</deletedAxiom>
<newAxiom>&apos;Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging&apos; SubClassOf &apos;Contrast-enhanced Magnetic Resonance Imaging&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C155787</classIRI>
<classLabel>Cognitive Behavior Therapy for Insomnia</classLabel>
<deletedAxiom>&apos;Cognitive Behavior Therapy for Insomnia&apos; SubClassOf &apos;Cognitive Behavior Therapy&apos;</deletedAxiom>
<newAxiom>&apos;Cognitive Behavior Therapy for Insomnia&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178996</classIRI>
<classLabel>Target Biospecimen is Plasma</classLabel>
<newAxiom>'Target Biospecimen is Plasma' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178997</classIRI>
<classLabel>Target Biospecimen is Serum</classLabel>
<newAxiom>'Target Biospecimen is Serum' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178998</classIRI>
<classLabel>Target Biospecimen is Sputum</classLabel>
<newAxiom>'Target Biospecimen is Sputum' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178999</classIRI>
<classLabel>Target Biospecimen is Venous Whole Blood</classLabel>
<newAxiom>'Target Biospecimen is Venous Whole Blood' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178992</classIRI>
<classLabel>Symptom Resolution Date</classLabel>
<newAxiom>'Symptom Resolution Date' SubClassOf 'Resolution Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178993</classIRI>
<classLabel>Target Biospecimen is Bronchoalveolar Lavage</classLabel>
<newAxiom>'Target Biospecimen is Bronchoalveolar Lavage' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178994</classIRI>
<classLabel>Target Biospecimen is Dried Blood Spot</classLabel>
<newAxiom>'Target Biospecimen is Dried Blood Spot' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178995</classIRI>
<classLabel>Target Biospecimen is Nasal Swab</classLabel>
<newAxiom>'Target Biospecimen is Nasal Swab' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178985</classIRI>
<classLabel>Seasonal Coronavirus Serology Test Result Provenance</classLabel>
<newAxiom>'Seasonal Coronavirus Serology Test Result Provenance' SubClassOf 'Provenance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178986</classIRI>
<classLabel>Semi-Quantitative Concept</classLabel>
<newAxiom>'Semi-Quantitative Concept' SubClassOf 'Property or Attribute'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178987</classIRI>
<classLabel>Serum Sample</classLabel>
<newAxiom>'Serum Sample' SubClassOf 'Blood Sample'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178988</classIRI>
<classLabel>Storage End Date and Time at 2-8 Degrees Celsius</classLabel>
<newAxiom>'Storage End Date and Time at 2-8 Degrees Celsius' SubClassOf 'Date and Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178981</classIRI>
<classLabel>Seasonal Coronavirus Molecular Test Result</classLabel>
<newAxiom>'Seasonal Coronavirus Molecular Test Result' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178982</classIRI>
<classLabel>Seasonal Coronavirus Molecular Test Result Provenance</classLabel>
<newAxiom>'Seasonal Coronavirus Molecular Test Result Provenance' SubClassOf 'Provenance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178983</classIRI>
<classLabel>Seasonal Coronavirus Serology Test Date</classLabel>
<newAxiom>'Seasonal Coronavirus Serology Test Date' SubClassOf 'Laboratory Test Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178984</classIRI>
<classLabel>Seasonal Coronavirus Serology Test Result</classLabel>
<newAxiom>'Seasonal Coronavirus Serology Test Result' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178989</classIRI>
<classLabel>Storage Start Date and Time at 2-8 Degrees Celsius</classLabel>
<newAxiom>'Storage Start Date and Time at 2-8 Degrees Celsius' SubClassOf 'Date and Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178990</classIRI>
<classLabel>Storage Start Date and Time at -80 Degrees Celsius or in Liquid Nitrogen</classLabel>
<newAxiom>'Storage Start Date and Time at -80 Degrees Celsius or in Liquid Nitrogen' SubClassOf 'Start Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178991</classIRI>
<classLabel>Storage Time at 2-8 Degrees Celsius</classLabel>
<newAxiom>'Storage Time at 2-8 Degrees Celsius' SubClassOf 'Period'</newAxiom>
<newAxiom>'Storage Time at 2-8 Degrees Celsius' SubClassOf 'Storage Condition'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178974</classIRI>
<classLabel>Sample Dilution</classLabel>
<newAxiom>'Sample Dilution' SubClassOf 'Biospecimen Condition'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178975</classIRI>
<classLabel>SARS-CoV-2 PCR Diagnosis Date</classLabel>
<newAxiom>'SARS-CoV-2 PCR Diagnosis Date' SubClassOf 'Date of Diagnosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178976</classIRI>
<classLabel>SARS-CoV-2 PCR Sample Collection Date</classLabel>
<newAxiom>'SARS-CoV-2 PCR Sample Collection Date' SubClassOf 'Sample Procurement Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178977</classIRI>
<classLabel>SARS-CoV-2 PCR Test Result</classLabel>
<newAxiom>'SARS-CoV-2 PCR Test Result' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178970</classIRI>
<classLabel>Reagent Name</classLabel>
<newAxiom>'Reagent Name' SubClassOf 'Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178971</classIRI>
<classLabel>Refrigerator</classLabel>
<newAxiom>'Refrigerator' SubClassOf 'Instrumentation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178972</classIRI>
<classLabel>Room Temperature Serum Clotting Time</classLabel>
<newAxiom>'Room Temperature Serum Clotting Time' SubClassOf 'Coagulation Study'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178973</classIRI>
<classLabel>Roswell Park Memorial Institute 1640 Medium</classLabel>
<newAxiom>'Roswell Park Memorial Institute 1640 Medium' SubClassOf 'Medium'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178978</classIRI>
<classLabel>SARS-CoV-2 PCR Test Result Provenance</classLabel>
<newAxiom>'SARS-CoV-2 PCR Test Result Provenance' SubClassOf 'Provenance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178979</classIRI>
<classLabel>Seasonal Coronavirus Infection Duration</classLabel>
<newAxiom>'Seasonal Coronavirus Infection Duration' SubClassOf 'Duration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178980</classIRI>
<classLabel>Seasonal Coronavirus Molecular Test Date</classLabel>
<newAxiom>'Seasonal Coronavirus Molecular Test Date' SubClassOf 'Laboratory Test Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178963</classIRI>
<classLabel>Other Vaccination</classLabel>
<newAxiom>'Other Vaccination' SubClassOf 'Vaccination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178964</classIRI>
<classLabel>Penicillin/Streptomycin Cell Culture Solution</classLabel>
<newAxiom>'Penicillin/Streptomycin Cell Culture Solution' SubClassOf 'Medium'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178965</classIRI>
<classLabel>Peripheral Blood Mononuclear Cell Sample</classLabel>
<newAxiom>'Peripheral Blood Mononuclear Cell Sample' SubClassOf 'Peripheral Blood'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178966</classIRI>
<classLabel>Pneumonia Vaccination</classLabel>
<newAxiom>'Pneumonia Vaccination' SubClassOf 'Vaccination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178960</classIRI>
<classLabel>Other Comorbidity</classLabel>
<newAxiom>'Other Comorbidity' SubClassOf 'Comorbid Condition'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178961</classIRI>
<classLabel>Other Disease Etiology</classLabel>
<newAxiom>'Other Disease Etiology' SubClassOf 'Etiology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178962</classIRI>
<classLabel>Other Symptom</classLabel>
<newAxiom>'Other Symptom' SubClassOf 'Symptom'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178967</classIRI>
<classLabel>Raw Laboratory Result</classLabel>
<newAxiom>'Raw Laboratory Result' SubClassOf 'Raw Data'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178968</classIRI>
<classLabel>Reagent Catalog Number</classLabel>
<newAxiom>'Reagent Catalog Number' SubClassOf 'Catalog Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178969</classIRI>
<classLabel>Reagent Expiration Date</classLabel>
<newAxiom>'Reagent Expiration Date' SubClassOf 'Expiration Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178952</classIRI>
<classLabel>Measurand Antibody Isotype</classLabel>
<newAxiom>'Measurand Antibody Isotype' SubClassOf 'Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178953</classIRI>
<classLabel>Measurand Antibody Type</classLabel>
<newAxiom>'Measurand Antibody Type' SubClassOf 'Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178954</classIRI>
<classLabel>Mechanical Ventilation Required</classLabel>
<newAxiom>'Mechanical Ventilation Required' SubClassOf 'Intervention Required'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178955</classIRI>
<classLabel>Minus 80 Degrees Celsius Freezer</classLabel>
<newAxiom>'Minus 80 Degrees Celsius Freezer' SubClassOf 'Freezer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178950</classIRI>
<classLabel>L-Glutamine Solution</classLabel>
<newAxiom>'L-Glutamine Solution' SubClassOf 'Medium'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178951</classIRI>
<classLabel>Liquid Nitrogen Freezer</classLabel>
<newAxiom>'Liquid Nitrogen Freezer' SubClassOf 'Freezer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178956</classIRI>
<classLabel>Number of False Negatives</classLabel>
<newAxiom>'Number of False Negatives' SubClassOf 'Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178957</classIRI>
<classLabel>Number of False Positives</classLabel>
<newAxiom>'Number of False Positives' SubClassOf 'Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178958</classIRI>
<classLabel>Number of True Negatives</classLabel>
<newAxiom>'Number of True Negatives' SubClassOf 'Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178959</classIRI>
<classLabel>Number of True Positives</classLabel>
<newAxiom>'Number of True Positives' SubClassOf 'Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178941</classIRI>
<classLabel>Immunoglobulin G and Immunoglobulin M Measurement</classLabel>
<newAxiom>'Immunoglobulin G and Immunoglobulin M Measurement' SubClassOf 'Immunoglobulin Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178942</classIRI>
<classLabel>Immunosuppressive Disorder</classLabel>
<newAxiom>'Immunosuppressive Disorder' SubClassOf 'Immune System Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178943</classIRI>
<classLabel>Initial Volume of Biospecimen</classLabel>
<newAxiom>'Initial Volume of Biospecimen' SubClassOf 'Volume'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178944</classIRI>
<classLabel>Initials of Person Making Aliquot</classLabel>
<newAxiom>'Initials of Person Making Aliquot' SubClassOf 'Person Initials'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178940</classIRI>
<classLabel>HIV Serology Test Result Provenance</classLabel>
<newAxiom>'HIV Serology Test Result Provenance' SubClassOf 'Provenance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178949</classIRI>
<classLabel>Intubation Required</classLabel>
<newAxiom>'Intubation Required' SubClassOf 'Intervention Required'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178945</classIRI>
<classLabel>Initials of Person who Began Storage of Sample at 2-8 Degrees Celsius</classLabel>
<newAxiom>'Initials of Person who Began Storage of Sample at 2-8 Degrees Celsius' SubClassOf 'Person Initials'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178946</classIRI>
<classLabel>Initials of Person who Ended Storage of Sample at 2-8 Degrees Celsius</classLabel>
<newAxiom>'Initials of Person who Ended Storage of Sample at 2-8 Degrees Celsius' SubClassOf 'Person Initials'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178947</classIRI>
<classLabel>Instrument Identification Number</classLabel>
<newAxiom>'Instrument Identification Number' SubClassOf 'Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178948</classIRI>
<classLabel>Interpretation of Laboratory Test</classLabel>
<newAxiom>'Interpretation of Laboratory Test' SubClassOf 'Clinical Interpretation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178930</classIRI>
<classLabel>Hepatitis B Surface Antigen Test Result</classLabel>
<newAxiom>'Hepatitis B Surface Antigen Test Result' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178931</classIRI>
<classLabel>Hepatitis B Surface Antigen Test Result Provenance</classLabel>
<newAxiom>'Hepatitis B Surface Antigen Test Result Provenance' SubClassOf 'Provenance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178932</classIRI>
<classLabel>Hepatitis B Vaccination</classLabel>
<newAxiom>'Hepatitis B Vaccination' SubClassOf 'Vaccination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178933</classIRI>
<classLabel>HEPES Solution</classLabel>
<newAxiom>'HEPES Solution' SubClassOf 'Medium'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178938</classIRI>
<classLabel>HIV Serology Test Date</classLabel>
<newAxiom>'HIV Serology Test Date' SubClassOf 'Laboratory Test Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178939</classIRI>
<classLabel>HIV Serology Test Result</classLabel>
<newAxiom>'HIV Serology Test Result' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178934</classIRI>
<classLabel>HIV Infection Duration</classLabel>
<newAxiom>'HIV Infection Duration' SubClassOf 'Duration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178935</classIRI>
<classLabel>HIV Molecular Test Date</classLabel>
<newAxiom>'HIV Molecular Test Date' SubClassOf 'Laboratory Test Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178936</classIRI>
<classLabel>HIV Molecular Test Result</classLabel>
<newAxiom>'HIV Molecular Test Result' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178937</classIRI>
<classLabel>HIV Molecular Test Result Provenance</classLabel>
<newAxiom>'HIV Molecular Test Result Provenance' SubClassOf 'Provenance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178920</classIRI>
<classLabel>Equipment Type</classLabel>
<newAxiom>'Equipment Type' SubClassOf 'Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178921</classIRI>
<classLabel>Equivocal Laboratory Test Result</classLabel>
<newAxiom>'Equivocal Laboratory Test Result' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178922</classIRI>
<classLabel>Extracorporeal Membrane Oxygenation Required</classLabel>
<newAxiom>'Extracorporeal Membrane Oxygenation Required' SubClassOf 'Intervention Required'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178927</classIRI>
<classLabel>Hepatitis B Serology Test Result</classLabel>
<newAxiom>'Hepatitis B Serology Test Result' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178928</classIRI>
<classLabel>Hepatitis B Serology Test Result Provenance</classLabel>
<newAxiom>'Hepatitis B Serology Test Result Provenance' SubClassOf 'Provenance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178929</classIRI>
<classLabel>Hepatitis B Surface Antigen Test Date</classLabel>
<newAxiom>'Hepatitis B Surface Antigen Test Date' SubClassOf 'Laboratory Test Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178923</classIRI>
<classLabel>Final Concentration of Biospecimen</classLabel>
<newAxiom>'Final Concentration of Biospecimen' SubClassOf 'Last Concentration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178924</classIRI>
<classLabel>HAART Duration</classLabel>
<newAxiom>'HAART Duration' SubClassOf 'Duration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178925</classIRI>
<classLabel>Hepatitis B Infection Duration</classLabel>
<newAxiom>'Hepatitis B Infection Duration' SubClassOf 'Duration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178926</classIRI>
<classLabel>Hepatitis B Serology Test Date</classLabel>
<newAxiom>'Hepatitis B Serology Test Date' SubClassOf 'Laboratory Test Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178910</classIRI>
<classLabel>EBV Molecular Test Date</classLabel>
<newAxiom>'EBV Molecular Test Date' SubClassOf 'Laboratory Test Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178911</classIRI>
<classLabel>EBV Molecular Test Result</classLabel>
<newAxiom>'EBV Molecular Test Result' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178916</classIRI>
<classLabel>EDTA-Treated Plasma Sample</classLabel>
<newAxiom>'EDTA-Treated Plasma Sample' SubClassOf 'Blood Sample'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178917</classIRI>
<classLabel>Emergency Use Authorization Status</classLabel>
<newAxiom>'Emergency Use Authorization Status' SubClassOf 'Product Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178918</classIRI>
<classLabel>Equipment Calibration Due Date</classLabel>
<newAxiom>'Equipment Calibration Due Date' SubClassOf 'Due Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178919</classIRI>
<classLabel>Equipment Identifier</classLabel>
<newAxiom>'Equipment Identifier' SubClassOf 'Unique Identifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178912</classIRI>
<classLabel>EBV Molecular Test Result Provenance</classLabel>
<newAxiom>'EBV Molecular Test Result Provenance' SubClassOf 'Provenance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178913</classIRI>
<classLabel>EBV Serology Test Date</classLabel>
<newAxiom>'EBV Serology Test Date' SubClassOf 'Laboratory Test Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178914</classIRI>
<classLabel>EBV Serology Test Result</classLabel>
<newAxiom>'EBV Serology Test Result' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178915</classIRI>
<classLabel>EBV Serology Test Result Provenance</classLabel>
<newAxiom>'EBV Serology Test Result Provenance' SubClassOf 'Provenance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178900</classIRI>
<classLabel>Cryovial Label</classLabel>
<newAxiom>'Cryovial Label' SubClassOf 'Label'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178905</classIRI>
<classLabel>Current Seasonal Coronavirus Infection</classLabel>
<newAxiom>'Current Seasonal Coronavirus Infection' SubClassOf 'Viral Infection'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178906</classIRI>
<classLabel>Density Gradient Medium</classLabel>
<newAxiom>'Density Gradient Medium' SubClassOf 'Medium'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178907</classIRI>
<classLabel>Derived Laboratory Result</classLabel>
<newAxiom>'Derived Laboratory Result' SubClassOf 'Derived Value'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178908</classIRI>
<classLabel>Dulbecco's Phosphate-Buffered Saline</classLabel>
<newAxiom>'Dulbecco's Phosphate-Buffered Saline' SubClassOf 'Saline'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178901</classIRI>
<classLabel>Current Cytomegalovirus Infection</classLabel>
<newAxiom>'Current Cytomegalovirus Infection' SubClassOf 'Cytomegaloviral Infection'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178902</classIRI>
<classLabel>Current EBV Infection</classLabel>
<newAxiom>'Current EBV Infection' SubClassOf 'EBV Infection'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178903</classIRI>
<classLabel>Current Hepatitis B Infection</classLabel>
<newAxiom>'Current Hepatitis B Infection' SubClassOf 'Hepatitis B Infection'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178904</classIRI>
<classLabel>Current HIV Infection</classLabel>
<newAxiom>'Current HIV Infection' SubClassOf 'HIV Infection'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178909</classIRI>
<classLabel>EBV Infection Duration</classLabel>
<newAxiom>'EBV Infection Duration' SubClassOf 'Duration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178721</classIRI>
<classLabel>SeroNet Biospecimen Metadata</classLabel>
<newAxiom>'SeroNet Biospecimen Metadata' SubClassOf 'SeroNet Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178722</classIRI>
<classLabel>SeroNet Assay Target Metadata</classLabel>
<newAxiom>'SeroNet Assay Target Metadata' SubClassOf 'SeroNet Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178723</classIRI>
<classLabel>SeroNet Assay Metadata</classLabel>
<newAxiom>'SeroNet Assay Metadata' SubClassOf 'SeroNet Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178724</classIRI>
<classLabel>SeroNet Aliquot Metadata</classLabel>
<newAxiom>'SeroNet Aliquot Metadata' SubClassOf 'SeroNet Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178720</classIRI>
<classLabel>SeroNet Confirmatory Test Result</classLabel>
<newAxiom>'SeroNet Confirmatory Test Result' SubClassOf 'SeroNet Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178725</classIRI>
<classLabel>SeroNet Equipment Metadata</classLabel>
<newAxiom>'SeroNet Equipment Metadata' SubClassOf 'SeroNet Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178726</classIRI>
<classLabel>SeroNet Reagent Metadata</classLabel>
<newAxiom>'SeroNet Reagent Metadata' SubClassOf 'SeroNet Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178727</classIRI>
<classLabel>SeroNet Consumable Metadata</classLabel>
<newAxiom>'SeroNet Consumable Metadata' SubClassOf 'SeroNet Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178710</classIRI>
<classLabel>KCNG4 Gene</classLabel>
<newAxiom>'KCNG4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Potassium Channel Binding'</newAxiom>
<newAxiom>'KCNG4 Gene' SubClassOf 'Ion Channel Protein Gene'</newAxiom>
<newAxiom>'KCNG4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Ion Transport Process'</newAxiom>
<newAxiom>'KCNG4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Voltage-Gated Potassium Ion Channel Activation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178711</classIRI>
<classLabel>KCNG4 wt Allele</classLabel>
<newAxiom>'KCNG4 wt Allele' SubClassOf 'KCNG4 Gene'</newAxiom>
<newAxiom>'KCNG4 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '16q24.1'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178712</classIRI>
<classLabel>Potassium Voltage-Gated Channel Subfamily G Member 4</classLabel>
<newAxiom>'Potassium Voltage-Gated Channel Subfamily G Member 4' EquivalentTo 'Ion Channel Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Ion Transport Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Potassium Channel Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Voltage-Gated Potassium Ion Channel Activation') and ('Gene_Product_Encoded_By_Gene' some 'KCNG4 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178713</classIRI>
<classLabel>STEEP1 Gene</classLabel>
<newAxiom>'STEEP1 Gene' SubClassOf 'Trafficking Protein Gene'</newAxiom>
<newAxiom>'STEEP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Interferon Signaling Process'</newAxiom>
<newAxiom>'STEEP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Subcellular Protein Targeting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178718</classIRI>
<classLabel>SeroNet Research Participant Metadata</classLabel>
<newAxiom>'SeroNet Research Participant Metadata' SubClassOf 'SeroNet Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178719</classIRI>
<classLabel>SeroNet Prior Test Result</classLabel>
<newAxiom>'SeroNet Prior Test Result' SubClassOf 'SeroNet Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178714</classIRI>
<classLabel>STEEP1 wt Allele</classLabel>
<newAxiom>'STEEP1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some 'Xq24'</newAxiom>
<newAxiom>'STEEP1 wt Allele' SubClassOf 'STEEP1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178715</classIRI>
<classLabel>STING ER Exit Protein</classLabel>
<newAxiom>'STING ER Exit Protein' EquivalentTo 'Transport Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoplasm') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Coiled-Coil Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Subcellular Protein Targeting') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Interferon Signaling Process') and ('Gene_Product_Encoded_By_Gene' some 'STEEP1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178716</classIRI>
<classLabel>Complete Remission in Leukemia</classLabel>
<newAxiom>'Complete Remission in Leukemia' SubClassOf 'Complete Remission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178717</classIRI>
<classLabel>Complete Response in Solid Tumors</classLabel>
<newAxiom>'Complete Response in Solid Tumors' SubClassOf 'Complete Remission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178700</classIRI>
<classLabel>Platinum-Refractory Ovarian Carcinoma</classLabel>
<newAxiom>'Platinum-Refractory Ovarian Carcinoma' EquivalentTo 'Refractory Ovarian Carcinoma' and 'Platinum-Refractory Malignant Female Reproductive System Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178701</classIRI>
<classLabel>SeroNet Terminology</classLabel>
<newAxiom>'SeroNet Terminology' SubClassOf 'Terminology Subset'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178702</classIRI>
<classLabel>Platinum-Refractory Primary Peritoneal Carcinoma</classLabel>
<newAxiom>'Platinum-Refractory Primary Peritoneal Carcinoma' EquivalentTo 'Refractory Primary Peritoneal Carcinoma' and ('Disease_Has_Finding' some 'Platinum-Refractory Disease')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178707</classIRI>
<classLabel>AEBP1 Gene</classLabel>
<newAxiom>'AEBP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Histogenic Process'</newAxiom>
<newAxiom>'AEBP1 Gene' SubClassOf 'Transcription Repressor/Corepressor Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178708</classIRI>
<classLabel>AEBP1 wt Allele</classLabel>
<newAxiom>'AEBP1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '7p13'</newAxiom>
<newAxiom>'AEBP1 wt Allele' SubClassOf 'AEBP1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178709</classIRI>
<classLabel>Adipocyte Enhancer-Binding Protein 1</classLabel>
<newAxiom>'Adipocyte Enhancer-Binding Protein 1' EquivalentTo 'Transcription Regulatory Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Osteoblast') and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleus') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoplasm') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Expressed_In_Tissue' some 'Adipose Tissue') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Protease Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Proline-Rich Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Transcription Repressor/Corepressor') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Histogenic Process') and ('Gene_Product_Encoded_By_Gene' some 'AEBP1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178703</classIRI>
<classLabel>APOM Gene</classLabel>
<newAxiom>'APOM Gene' SubClassOf 'Transport Protein Gene'</newAxiom>
<newAxiom>'APOM Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Lipid Binding'</newAxiom>
<newAxiom>'APOM Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Lipid Transport'</newAxiom>
<newAxiom>'APOM Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cholesterol Homeostasis'</newAxiom>
<newAxiom>'APOM Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Lipid Metabolic Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178704</classIRI>
<classLabel>APOM wt Allele</classLabel>
<newAxiom>'APOM wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '6p21.33'</newAxiom>
<newAxiom>'APOM wt Allele' SubClassOf 'APOM Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178705</classIRI>
<classLabel>Apolipoprotein M</classLabel>
<newAxiom>'Apolipoprotein M' EquivalentTo 'Transport Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Expressed_In_Tissue' some 'Plasma') and ('Gene_Product_Is_Physical_Part_Of' some 'Lipoprotein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Lipid Metabolic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Lipid Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Lipid Transport') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cholesterol Homeostasis') and ('Gene_Product_Encoded_By_Gene' some 'APOM Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178706</classIRI>
<classLabel>Anti-STn Antibody-drug Conjugate SGN-STNV</classLabel>
<newAxiom>'Anti-STn Antibody-drug Conjugate SGN-STNV' SubClassOf 'Immunoconjugate'</newAxiom>
<newAxiom>'Anti-STn Antibody-drug Conjugate SGN-STNV' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178897</classIRI>
<classLabel>Consumable Name</classLabel>
<newAxiom>'Consumable Name' SubClassOf 'Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178898</classIRI>
<classLabel>Controlled Rate Freezer</classLabel>
<newAxiom>'Controlled Rate Freezer' SubClassOf 'Freezer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178899</classIRI>
<classLabel>COVID-19 Disease Severity Scale</classLabel>
<newAxiom>'COVID-19 Disease Severity Scale' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178893</classIRI>
<classLabel>Collection Tube Type Lot Number</classLabel>
<newAxiom>'Collection Tube Type Lot Number' SubClassOf 'Lot Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178894</classIRI>
<classLabel>Consumable Catalog Number</classLabel>
<newAxiom>'Consumable Catalog Number' SubClassOf 'Catalog Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178895</classIRI>
<classLabel>Consumable Expiration Date</classLabel>
<newAxiom>'Consumable Expiration Date' SubClassOf 'Expiration Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178896</classIRI>
<classLabel>Consumable Lot Number</classLabel>
<newAxiom>'Consumable Lot Number' SubClassOf 'Lot Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178886</classIRI>
<classLabel>CMV Molecular Test Result Provenance</classLabel>
<newAxiom>'CMV Molecular Test Result Provenance' SubClassOf 'Provenance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178887</classIRI>
<classLabel>CMV Serology Test Date</classLabel>
<newAxiom>'CMV Serology Test Date' SubClassOf 'Laboratory Test Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178888</classIRI>
<classLabel>CMV Serology Test Result</classLabel>
<newAxiom>'CMV Serology Test Result' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178889</classIRI>
<classLabel>CMV Serology Test Result Provenance</classLabel>
<newAxiom>'CMV Serology Test Result Provenance' SubClassOf 'Provenance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178882</classIRI>
<classLabel>Class 3 Obesity</classLabel>
<newAxiom>'Class 3 Obesity' SubClassOf 'Obesity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178883</classIRI>
<classLabel>CMV Infection Duration</classLabel>
<newAxiom>'CMV Infection Duration' SubClassOf 'Duration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178884</classIRI>
<classLabel>CMV Molecular Test Date</classLabel>
<newAxiom>'CMV Molecular Test Date' SubClassOf 'Laboratory Test Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178885</classIRI>
<classLabel>CMV Molecular Test Result</classLabel>
<newAxiom>'CMV Molecular Test Result' SubClassOf 'Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178890</classIRI>
<classLabel>Collection Tube Type</classLabel>
<newAxiom>'Collection Tube Type' SubClassOf 'Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178891</classIRI>
<classLabel>Collection Tube Type Catalog Number</classLabel>
<newAxiom>'Collection Tube Type Catalog Number' SubClassOf 'Catalog Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178892</classIRI>
<classLabel>Collection Tube Type Expiration Date</classLabel>
<newAxiom>'Collection Tube Type Expiration Date' SubClassOf 'Expiration Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178875</classIRI>
<classLabel>Biospecimen Processor Initials</classLabel>
<newAxiom>'Biospecimen Processor Initials' SubClassOf 'Person Initials'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178876</classIRI>
<classLabel>Biospecimen Receipt Time</classLabel>
<newAxiom>'Biospecimen Receipt Time' SubClassOf 'Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178877</classIRI>
<classLabel>Calibration Type</classLabel>
<newAxiom>'Calibration Type' SubClassOf 'Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178878</classIRI>
<classLabel>Calibrator High Reference</classLabel>
<newAxiom>'Calibrator High Reference' SubClassOf 'Reference Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178871</classIRI>
<classLabel>Biospecimen Group</classLabel>
<newAxiom>'Biospecimen Group' SubClassOf 'Group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178872</classIRI>
<classLabel>Biospecimen Identifier</classLabel>
<newAxiom>'Biospecimen Identifier' SubClassOf 'Specimen Identifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178873</classIRI>
<classLabel>Biospecimen Processing Company or Clinic</classLabel>
<newAxiom>'Biospecimen Processing Company or Clinic' SubClassOf 'Clinic'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178874</classIRI>
<classLabel>Biospecimen Processing Date</classLabel>
<newAxiom>'Biospecimen Processing Date' SubClassOf 'Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178879</classIRI>
<classLabel>Calibrator Low Reference</classLabel>
<newAxiom>'Calibrator Low Reference' SubClassOf 'Reference Point'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178880</classIRI>
<classLabel>Cell Culture Grade Dimethyl Sulfoxide</classLabel>
<newAxiom>'Cell Culture Grade Dimethyl Sulfoxide' SubClassOf 'Dimethyl Sulfoxide'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178881</classIRI>
<classLabel>Centrifugation Time</classLabel>
<newAxiom>'Centrifugation Time' SubClassOf 'Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178864</classIRI>
<classLabel>Assay Target Antigen Sub-Region</classLabel>
<newAxiom>'Assay Target Antigen Sub-Region' SubClassOf 'Region'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178865</classIRI>
<classLabel>Assay Technology Type</classLabel>
<newAxiom>'Assay Technology Type' SubClassOf 'Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178866</classIRI>
<classLabel>Automated Cell Counter</classLabel>
<newAxiom>'Automated Cell Counter' SubClassOf 'Instrumentation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178867</classIRI>
<classLabel>Biospecimen Collection Company or Clinic</classLabel>
<newAxiom>'Biospecimen Collection Company or Clinic' SubClassOf 'Clinic'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178860</classIRI>
<classLabel>Assay Result Type</classLabel>
<newAxiom>'Assay Result Type' SubClassOf 'Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178861</classIRI>
<classLabel>Assay Result Unit</classLabel>
<newAxiom>'Assay Result Unit' SubClassOf 'Measurement Unit Description'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178862</classIRI>
<classLabel>Assay Target Antigen</classLabel>
<newAxiom>'Assay Target Antigen' SubClassOf 'Target'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178863</classIRI>
<classLabel>Assay Target Antigen Source</classLabel>
<newAxiom>'Assay Target Antigen Source' SubClassOf 'Source'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178868</classIRI>
<classLabel>Biospecimen Collection Date</classLabel>
<newAxiom>'Biospecimen Collection Date' SubClassOf 'Sample Procurement Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178869</classIRI>
<classLabel>Biospecimen Collection Time</classLabel>
<newAxiom>'Biospecimen Collection Time' SubClassOf 'Collection Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178870</classIRI>
<classLabel>Biospecimen Collector Initials</classLabel>
<newAxiom>'Biospecimen Collector Initials' SubClassOf 'Person Initials'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178853</classIRI>
<classLabel>Assay Internal Control</classLabel>
<newAxiom>'Assay Internal Control' SubClassOf 'Control Analyte'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178854</classIRI>
<classLabel>Assay Kit Lot Number</classLabel>
<newAxiom>'Assay Kit Lot Number' SubClassOf 'Lot Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178855</classIRI>
<classLabel>Assay Manufacturer</classLabel>
<newAxiom>'Assay Manufacturer' SubClassOf 'Manufacturer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178856</classIRI>
<classLabel>Assay Multiplicity</classLabel>
<newAxiom>'Assay Multiplicity' SubClassOf 'Multiplicity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178850</classIRI>
<classLabel>Assay Cutoff Unit</classLabel>
<newAxiom>'Assay Cutoff Unit' SubClassOf 'Measurement Unit Description'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178851</classIRI>
<classLabel>Assay External Control</classLabel>
<newAxiom>'Assay External Control' SubClassOf 'Control Analyte'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178852</classIRI>
<classLabel>Assay Internal and External Controls</classLabel>
<newAxiom>'Assay Internal and External Controls' SubClassOf 'Control Analyte'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178857</classIRI>
<classLabel>Assay Name</classLabel>
<newAxiom>'Assay Name' SubClassOf 'Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178858</classIRI>
<classLabel>Assay Performance Statistics Source</classLabel>
<newAxiom>'Assay Performance Statistics Source' SubClassOf 'Source'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178859</classIRI>
<classLabel>Assay Replicate</classLabel>
<newAxiom>'Assay Replicate' SubClassOf 'Sequence Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178842</classIRI>
<classLabel>50 mL Polypropylene Tube</classLabel>
<newAxiom>'50 mL Polypropylene Tube' SubClassOf 'Tube Device'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178843</classIRI>
<classLabel>Acute Respiratory Distress</classLabel>
<newAxiom>'Acute Respiratory Distress' SubClassOf 'Respiratory Distress'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178844</classIRI>
<classLabel>Aliquot Tube Type</classLabel>
<newAxiom>'Aliquot Tube Type' SubClassOf 'Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178845</classIRI>
<classLabel>Aliquot Tube Type Catalog Number</classLabel>
<newAxiom>'Aliquot Tube Type Catalog Number' SubClassOf 'Catalog Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178840</classIRI>
<classLabel>Have Felt So Sad, Discouraged, Hopeless, or Had So Many Problems Wondered if Anything was Worthwhile</classLabel>
<newAxiom>'Have Felt So Sad, Discouraged, Hopeless, or Had So Many Problems Wondered if Anything was Worthwhile' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178841</classIRI>
<classLabel>15 mL Conical Tube</classLabel>
<newAxiom>'15 mL Conical Tube' SubClassOf 'Tube Device'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178846</classIRI>
<classLabel>Aliquot Tube Type Expiration Date</classLabel>
<newAxiom>'Aliquot Tube Type Expiration Date' SubClassOf 'Expiration Date'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178847</classIRI>
<classLabel>Aliquot Tube Type Lot Number</classLabel>
<newAxiom>'Aliquot Tube Type Lot Number' SubClassOf 'Lot Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178848</classIRI>
<classLabel>Aliquot Unit</classLabel>
<newAxiom>'Aliquot Unit' SubClassOf 'Measurement Unit Description'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178849</classIRI>
<classLabel>Assay Control Type</classLabel>
<newAxiom>'Assay Control Type' SubClassOf 'Type'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178831</classIRI>
<classLabel>Feel I am Not a Healthy Person</classLabel>
<newAxiom>'Feel I am Not a Healthy Person' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178832</classIRI>
<classLabel>Feel Different from Other People</classLabel>
<newAxiom>'Feel Different from Other People' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178833</classIRI>
<classLabel>Hpk1 Inhibitor BGB-15025</classLabel>
<newAxiom>'Hpk1 Inhibitor BGB-15025' SubClassOf 'ALK Inhibitor'</newAxiom>
<newAxiom>'Hpk1 Inhibitor BGB-15025' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178834</classIRI>
<classLabel>Cannot Do Many Things I Want to Do</classLabel>
<newAxiom>'Cannot Do Many Things I Want to Do' SubClassOf 'Ability Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178830</classIRI>
<classLabel>Feel Ashamed</classLabel>
<newAxiom>'Feel Ashamed' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178839</classIRI>
<classLabel>Possibility of Bowel Accidents is Always On My Mind</classLabel>
<newAxiom>'Possibility of Bowel Accidents is Always On My Mind' SubClassOf 'Worry Question'</newAxiom>
<newAxiom>'Possibility of Bowel Accidents is Always On My Mind' SubClassOf 'Continence or Incontinence Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178835</classIRI>
<classLabel>Worry about Bowel Accidents</classLabel>
<newAxiom>'Worry about Bowel Accidents' SubClassOf 'Worry Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178836</classIRI>
<classLabel>Worry about Others Smelling Stool on Me</classLabel>
<newAxiom>'Worry about Others Smelling Stool on Me' SubClassOf 'Worry Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178837</classIRI>
<classLabel>Enjoy Life Less</classLabel>
<newAxiom>'Enjoy Life Less' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178838</classIRI>
<classLabel>Have Sex Less Often than Would Like To</classLabel>
<newAxiom>'Have Sex Less Often than Would Like To' SubClassOf 'Sex Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178820</classIRI>
<classLabel>Stay Near Restroom as Much as Possible When Away from Home</classLabel>
<newAxiom>'Stay Near Restroom as Much as Possible When Away from Home' SubClassOf 'Behavior Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178821</classIRI>
<classLabel>Try to Prevent Bowel Accidents by Staying Very Near Bathroom</classLabel>
<newAxiom>'Try to Prevent Bowel Accidents by Staying Very Near Bathroom' SubClassOf 'Behavior Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178822</classIRI>
<classLabel>Specifically Locate Bathrooms When Going Someplace New</classLabel>
<newAxiom>'Specifically Locate Bathrooms When Going Someplace New' SubClassOf 'Behavior Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178823</classIRI>
<classLabel>Important to Plan Daily Activity Schedule around Bowel Pattern</classLabel>
<newAxiom>'Important to Plan Daily Activity Schedule around Bowel Pattern' SubClassOf 'How Important Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178828</classIRI>
<classLabel>Cannot Hold Bowel Movement Long Enough to Reach Bathroom</classLabel>
<newAxiom>'Cannot Hold Bowel Movement Long Enough to Reach Bathroom' SubClassOf 'Continence or Incontinence Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178829</classIRI>
<classLabel>Leak Stool Without Knowing It</classLabel>
<newAxiom>'Leak Stool Without Knowing It' SubClassOf 'Continence or Incontinence Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178824</classIRI>
<classLabel>Worry about Being Unable to Reach Toilet in Time</classLabel>
<newAxiom>'Worry about Being Unable to Reach Toilet in Time' SubClassOf 'Worry Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178825</classIRI>
<classLabel>Feel I Have No Control Over My Bowels</classLabel>
<newAxiom>'Feel I Have No Control Over My Bowels' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178826</classIRI>
<classLabel>Rothmund–Thomson Syndrome Type 1</classLabel>
<newAxiom>'Rothmund–Thomson Syndrome Type 1' EquivalentTo 'Rothmund-Thomson Syndrome' and ('Disease_May_Have_Associated_Disease' some 'Juvenile Cataract') and ('Disease_Excludes_Molecular_Abnormality' some 'RECQL4 Gene Mutation')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178827</classIRI>
<classLabel>Rothmund–Thomson Syndrome Type 2</classLabel>
<newAxiom>'Rothmund–Thomson Syndrome Type 2' EquivalentTo 'Rothmund-Thomson Syndrome' and ('Disease_Has_Molecular_Abnormality' some 'RECQL4 Gene Mutation') and ('Disease_May_Have_Associated_Disease' some 'Skin Basal Cell Carcinoma') and ('Disease_May_Have_Associated_Disease' some 'Skin Squamous Cell Carcinoma') and ('Disease_May_Have_Associated_Disease' some 'Osteosarcoma') and ('Disease_Mapped_To_Gene' some 'RECQL4 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178810</classIRI>
<classLabel>Due to Accidental Bowel Leakage</classLabel>
<newAxiom>'Due to Accidental Bowel Leakage' SubClassOf 'Continence or Incontinence Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178811</classIRI>
<classLabel>Afraid to Go Out</classLabel>
<newAxiom>'Afraid to Go Out' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178812</classIRI>
<classLabel>Avoid Visiting Friends</classLabel>
<newAxiom>'Avoid Visiting Friends' SubClassOf 'Avoidance Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178817</classIRI>
<classLabel>Difficult to Get Out and Do Things</classLabel>
<newAxiom>'Difficult to Get Out and Do Things' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178818</classIRI>
<classLabel>Behavior Question</classLabel>
<newAxiom>'Behavior Question' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178819</classIRI>
<classLabel>Cut Down on How Much Eaten Before Going Out</classLabel>
<newAxiom>'Cut Down on How Much Eaten Before Going Out' SubClassOf 'Behavior Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178813</classIRI>
<classLabel>Avoid Staying Overnight Away from Home</classLabel>
<newAxiom>'Avoid Staying Overnight Away from Home' SubClassOf 'Avoidance Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178814</classIRI>
<classLabel>Avoid Traveling</classLabel>
<newAxiom>'Avoid Traveling' SubClassOf 'Avoidance Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178815</classIRI>
<classLabel>Avoid Traveling by Plane or Train</classLabel>
<newAxiom>'Avoid Traveling by Plane or Train' SubClassOf 'Avoidance Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178816</classIRI>
<classLabel>Avoid Going Out to Eat</classLabel>
<newAxiom>'Avoid Going Out to Eat' SubClassOf 'Avoidance Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178808</classIRI>
<classLabel>Fecal Incontinence Quality of Life Scale</classLabel>
<newAxiom>'Fecal Incontinence Quality of Life Scale' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178809</classIRI>
<classLabel>Continence or Incontinence Question</classLabel>
<newAxiom>'Continence or Incontinence Question' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178556</classIRI>
<classLabel>Refractory Aggressive T-Cell Non-Hodgkin Lymphoma</classLabel>
<newAxiom>'Refractory Aggressive T-Cell Non-Hodgkin Lymphoma' EquivalentTo 'Refractory Aggressive Non-Hodgkin Lymphoma' and 'Aggressive T-Cell Non-Hodgkin Lymphoma' and 'Refractory T-Cell Non-Hodgkin Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178557</classIRI>
<classLabel>FOS Gene Rearrangement</classLabel>
<newAxiom>'FOS Gene Rearrangement' SubClassOf 'Cytogenetic_Abnormality_Involves_Chromosome' some 'Chromosome 14'</newAxiom>
<newAxiom>'FOS Gene Rearrangement' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'FOS Gene'</newAxiom>
<newAxiom>'FOS Gene Rearrangement' SubClassOf 'Gene Rearrangement Abnormality'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178558</classIRI>
<classLabel>Metastatic Low Grade Glioma</classLabel>
<newAxiom>'Metastatic Low Grade Glioma' EquivalentTo 'Low Grade Glioma' and 'Metastatic Primary Malignant Central Nervous System Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178559</classIRI>
<classLabel>Metastatic Low Grade Astrocytoma</classLabel>
<newAxiom>'Metastatic Low Grade Astrocytoma' EquivalentTo 'Low Grade Astrocytoma' and 'Metastatic Low Grade Glioma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178552</classIRI>
<classLabel>Geboes Grading System</classLabel>
<newAxiom>'Geboes Grading System' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178553</classIRI>
<classLabel>Recurrent Aggressive B-Cell Non-Hodgkin Lymphoma</classLabel>
<newAxiom>'Recurrent Aggressive B-Cell Non-Hodgkin Lymphoma' EquivalentTo 'Recurrent Aggressive Non-Hodgkin Lymphoma' and 'Aggressive B-Cell Non-Hodgkin Lymphoma' and 'Recurrent B-Cell Non-Hodgkin Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178554</classIRI>
<classLabel>Recurrent Aggressive T-Cell Non-Hodgkin Lymphoma</classLabel>
<newAxiom>'Recurrent Aggressive T-Cell Non-Hodgkin Lymphoma' EquivalentTo 'Recurrent Aggressive Non-Hodgkin Lymphoma' and 'Aggressive T-Cell Non-Hodgkin Lymphoma' and 'Recurrent T-Cell Non-Hodgkin Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178555</classIRI>
<classLabel>Refractory Aggressive B-Cell Non-Hodgkin Lymphoma</classLabel>
<newAxiom>'Refractory Aggressive B-Cell Non-Hodgkin Lymphoma' EquivalentTo 'Refractory Aggressive Non-Hodgkin Lymphoma' and 'Aggressive B-Cell Non-Hodgkin Lymphoma' and 'Refractory B-Cell Non-Hodgkin Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178560</classIRI>
<classLabel>Biopsy Twinkling Marker Ultrasound Detection</classLabel>
<newAxiom>'Biopsy Twinkling Marker Ultrasound Detection' SubClassOf 'Detection'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178561</classIRI>
<classLabel>Neoplastic Vacuolated Cell</classLabel>
<newAxiom>'Neoplastic Vacuolated Cell' SubClassOf 'Neoplastic Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178562</classIRI>
<classLabel>KRAS G12C Inhibitor D-1553</classLabel>
<newAxiom>'KRAS G12C Inhibitor D-1553' SubClassOf 'Ras Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178545</classIRI>
<classLabel>FAAP20 Gene Mutation</classLabel>
<newAxiom>'FAAP20 Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'FAAP20 Gene'</newAxiom>
<newAxiom>'FAAP20 Gene Mutation' SubClassOf 'Gene Variant'</newAxiom>
<newAxiom>'FAAP20 Gene Mutation' SubClassOf 'Fanconi Anemia Complementation Group Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178547</classIRI>
<classLabel>Aggressive T-Cell Non-Hodgkin Lymphoma</classLabel>
<newAxiom>'Aggressive T-Cell Non-Hodgkin Lymphoma' EquivalentTo 'T-Cell Non-Hodgkin Lymphoma' and 'Aggressive Non-Hodgkin Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178548</classIRI>
<classLabel>SSEA-4 Antigen</classLabel>
<newAxiom>'SSEA-4 Antigen' SubClassOf 'Ganglioside'</newAxiom>
<newAxiom>'SSEA-4 Antigen' SubClassOf 'Tumor Antigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178541</classIRI>
<classLabel>Aggressive B-Cell Non-Hodgkin Lymphoma</classLabel>
<newAxiom>'Aggressive B-Cell Non-Hodgkin Lymphoma' EquivalentTo 'B-Cell Non-Hodgkin Lymphoma' and 'Aggressive Non-Hodgkin Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178542</classIRI>
<classLabel>FAAP20 Gene</classLabel>
<newAxiom>'FAAP20 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'DNA Repair'</newAxiom>
<newAxiom>'FAAP20 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'DNA Binding'</newAxiom>
<newAxiom>'FAAP20 Gene' SubClassOf 'FA Complementation Group Gene'</newAxiom>
<newAxiom>'FAAP20 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Metal Ion Binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178543</classIRI>
<classLabel>FAAP20 wt Allele</classLabel>
<newAxiom>'FAAP20 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '1p36.33'</newAxiom>
<newAxiom>'FAAP20 wt Allele' SubClassOf 'FAAP20 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178544</classIRI>
<classLabel>Fanconi Anemia Core Complex-Associated Protein 20</classLabel>
<newAxiom>'Fanconi Anemia Core Complex-Associated Protein 20' EquivalentTo 'DNA Repair Protein' and ('Gene_Product_Has_Organism_Source' some 'Human') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Metal Binding Site') and ('Gene_Product_Has_Biochemical_Function' some 'Fanconi Anemia Complementation Group Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Repair') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Metal Ion Binding') and ('Gene_Product_Encoded_By_Gene' some 'FAAP20 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178549</classIRI>
<classLabel>TRA-1-81 Antigen</classLabel>
<newAxiom>'TRA-1-81 Antigen' SubClassOf 'Tumor Antigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178550</classIRI>
<classLabel>TRA-1-60 Antigen</classLabel>
<newAxiom>'TRA-1-60 Antigen' SubClassOf 'Tumor Antigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178551</classIRI>
<classLabel>Mutation Load</classLabel>
<newAxiom>'Mutation Load' SubClassOf 'Burden'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178534</classIRI>
<classLabel>Carnoy's Solution</classLabel>
<newAxiom>'Carnoy's Solution' SubClassOf 'Fixative'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178535</classIRI>
<classLabel>PRSS1 Protein Variant</classLabel>
<newAxiom>'PRSS1 Protein Variant' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'PRSS1 Gene Mutation'</newAxiom>
<newAxiom>'PRSS1 Protein Variant' SubClassOf 'Gene Product Sequence Variation'</newAxiom>
<newAxiom>'PRSS1 Protein Variant' SubClassOf 'Gene_Product_Variant_Of_Gene_Product' some 'Trypsin-1'</newAxiom>
<newAxiom>'PRSS1 Protein Variant' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'PRSS1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178536</classIRI>
<classLabel>Poloxamer</classLabel>
<newAxiom>'Poloxamer' SubClassOf 'Fixative'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178537</classIRI>
<classLabel>EPCAM Protein Variant</classLabel>
<newAxiom>'EPCAM Protein Variant' SubClassOf 'Gene Product Sequence Variation'</newAxiom>
<newAxiom>'EPCAM Protein Variant' SubClassOf 'Gene_Product_Variant_Of_Gene_Product' some 'Epithelial Cell Adhesion Molecule'</newAxiom>
<newAxiom>'EPCAM Protein Variant' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'EPCAM Gene'</newAxiom>
<newAxiom>'EPCAM Protein Variant' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'EPCAM Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178530</classIRI>
<classLabel>MLH1 Protein Variant</classLabel>
<newAxiom>'MLH1 Protein Variant' SubClassOf 'Gene Product Sequence Variation'</newAxiom>
<newAxiom>'MLH1 Protein Variant' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'MLH1 Gene'</newAxiom>
<newAxiom>'MLH1 Protein Variant' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MLH1 Gene Mutation'</newAxiom>
<newAxiom>'MLH1 Protein Variant' SubClassOf 'Gene_Product_Variant_Of_Gene_Product' some 'DNA Mismatch Repair Protein Mlh1'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178531</classIRI>
<classLabel>MSH6 Protein Variant</classLabel>
<newAxiom>'MSH6 Protein Variant' SubClassOf 'Gene Product Sequence Variation'</newAxiom>
<newAxiom>'MSH6 Protein Variant' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'MSH6 Gene'</newAxiom>
<newAxiom>'MSH6 Protein Variant' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'MSH6 Gene Mutation'</newAxiom>
<newAxiom>'MSH6 Protein Variant' SubClassOf 'Gene_Product_Variant_Of_Gene_Product' some 'DNA Mismatch Repair Protein Msh6'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178532</classIRI>
<classLabel>ATM Protein Variant</classLabel>
<newAxiom>'ATM Protein Variant' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'ATM Gene'</newAxiom>
<newAxiom>'ATM Protein Variant' SubClassOf 'Gene_Product_Variant_Of_Gene_Product' some 'Serine-Protein Kinase ATM'</newAxiom>
<newAxiom>'ATM Protein Variant' SubClassOf 'Gene Product Sequence Variation'</newAxiom>
<newAxiom>'ATM Protein Variant' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'ATM Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178533</classIRI>
<classLabel>STK11 Protein Variant</classLabel>
<newAxiom>'STK11 Protein Variant' SubClassOf 'Gene Product Sequence Variation'</newAxiom>
<newAxiom>'STK11 Protein Variant' SubClassOf 'Gene_Product_Variant_Of_Gene_Product' some 'Serine/Threonine-Protein Kinase STK11'</newAxiom>
<newAxiom>'STK11 Protein Variant' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'STK11 Gene'</newAxiom>
<newAxiom>'STK11 Protein Variant' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'STK11 Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178538</classIRI>
<classLabel>PALB2 Protein Variant</classLabel>
<newAxiom>'PALB2 Protein Variant' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'PALB2 Gene Mutation'</newAxiom>
<newAxiom>'PALB2 Protein Variant' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'PALB2 Gene'</newAxiom>
<newAxiom>'PALB2 Protein Variant' SubClassOf 'Gene Product Sequence Variation'</newAxiom>
<newAxiom>'PALB2 Protein Variant' SubClassOf 'Gene_Product_Variant_Of_Gene_Product' some 'Partner and Localizer of BRCA2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178539</classIRI>
<classLabel>Biological Cryopreservation Medium</classLabel>
<newAxiom>'Biological Cryopreservation Medium' SubClassOf 'Reagent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178540</classIRI>
<classLabel>FAN1 Gene Mutation</classLabel>
<newAxiom>'FAN1 Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'FAN1 Gene'</newAxiom>
<newAxiom>'FAN1 Gene Mutation' SubClassOf 'DNA Repair Gene Mutation'</newAxiom>
<newAxiom>'FAN1 Gene Mutation' SubClassOf 'Gene Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178523</classIRI>
<classLabel>Yolk Sac Tumor with Somatic-Type Malignancy</classLabel>
<newAxiom>'Yolk Sac Tumor with Somatic-Type Malignancy' EquivalentTo 'Yolk Sac Tumor' and ('Disease_Has_Associated_Disease' some 'Somatic-Type Malignancy')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178524</classIRI>
<classLabel>MCPyV Positive</classLabel>
<newAxiom>'MCPyV Positive' SubClassOf 'Positive Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178525</classIRI>
<classLabel>SARS Coronavirus 2 RNA Positive</classLabel>
<newAxiom>'SARS Coronavirus 2 RNA Positive' SubClassOf 'Positive Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178526</classIRI>
<classLabel>Elevated HMGA2</classLabel>
<newAxiom>'Elevated HMGA2' SubClassOf 'Elevated Expression'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178520</classIRI>
<classLabel>TYRP1 Positive</classLabel>
<newAxiom>'TYRP1 Positive' SubClassOf 'Expression Positive'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178521</classIRI>
<classLabel>Pharyngeal Melanoma</classLabel>
<newAxiom>'Pharyngeal Melanoma' EquivalentTo 'Mucosal Melanoma of the Head and Neck' and 'Malignant Pharyngeal Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Pharynx')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178522</classIRI>
<classLabel>Nasopharyngeal Melanoma</classLabel>
<newAxiom>'Nasopharyngeal Melanoma' EquivalentTo 'Pharyngeal Melanoma' and 'Malignant Nasopharyngeal Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Nasopharynx')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178527</classIRI>
<classLabel>TNFRSF8 Negative</classLabel>
<newAxiom>'TNFRSF8 Negative' SubClassOf 'Receptor Status'</newAxiom>
<newAxiom>'TNFRSF8 Negative' SubClassOf 'Expression Negative'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178528</classIRI>
<classLabel>Mass Spectrometry-based Cancer Detection via Hand-held Extraction Device</classLabel>
<newAxiom>'Mass Spectrometry-based Cancer Detection via Hand-held Extraction Device' SubClassOf 'Cancer Detection'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178529</classIRI>
<classLabel>PMS2 Protein Variant</classLabel>
<newAxiom>'PMS2 Protein Variant' SubClassOf 'Gene_Product_Variant_Of_Gene_Product' some 'Mismatch Repair Endonuclease PMS2'</newAxiom>
<newAxiom>'PMS2 Protein Variant' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'PMS2 Gene'</newAxiom>
<newAxiom>'PMS2 Protein Variant' SubClassOf 'Gene Product Sequence Variation'</newAxiom>
<newAxiom>'PMS2 Protein Variant' SubClassOf 'Gene_Product_Sequence_Variation_Encoded_By_Gene_Mutant' some 'PMS2 Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178512</classIRI>
<classLabel>RET Gene Mutation Negative</classLabel>
<newAxiom>'RET Gene Mutation Negative' SubClassOf 'Wildtype Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178513</classIRI>
<classLabel>SRSF2 NP_003007.2:p.P95X</classLabel>
<newAxiom>'SRSF2 NP_003007.2:p.P95X' SubClassOf 'SRSF2 Protein Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178514</classIRI>
<classLabel>Brain Metastasis Velocity Greater Than or Equal to 4 per Year</classLabel>
<newAxiom>'Brain Metastasis Velocity Greater Than or Equal to 4 per Year' SubClassOf 'Radiologic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178515</classIRI>
<classLabel>ALCAM Positive</classLabel>
<newAxiom>'ALCAM Positive' SubClassOf 'Expression Positive'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178510</classIRI>
<classLabel>ZRSR2 Gene Mutation Negative</classLabel>
<newAxiom>'ZRSR2 Gene Mutation Negative' SubClassOf 'Wildtype Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178511</classIRI>
<classLabel>SF3B1 Gene Mutation Negative</classLabel>
<newAxiom>'SF3B1 Gene Mutation Negative' SubClassOf 'Wildtype Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178516</classIRI>
<classLabel>EGFRvIII Negative</classLabel>
<newAxiom>'EGFRvIII Negative' SubClassOf 'Receptor Status'</newAxiom>
<newAxiom>'EGFRvIII Negative' SubClassOf 'Expression Negative'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178517</classIRI>
<classLabel>Penile Mucosal Melanoma</classLabel>
<newAxiom>'Penile Mucosal Melanoma' EquivalentTo 'Penile Melanoma' and 'Mucosal Melanoma of the Genitourinary System'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178518</classIRI>
<classLabel>Penile Cutaneous Melanoma</classLabel>
<newAxiom>'Penile Cutaneous Melanoma' EquivalentTo 'Penile Melanoma' and 'Cutaneous Melanoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178519</classIRI>
<classLabel>Gastric Melanoma</classLabel>
<newAxiom>'Gastric Melanoma' EquivalentTo 'Mucosal Melanoma of the Digestive System' and 'Malignant Gastric Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Stomach')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178501</classIRI>
<classLabel>Allogeneic Invariant Natural Killer T-cells agenT-797</classLabel>
<newAxiom>'Allogeneic Invariant Natural Killer T-cells agenT-797' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Allogeneic Invariant Natural Killer T-cells agenT-797' SubClassOf 'Therapeutic Allogeneic Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178502</classIRI>
<classLabel>Multisystem Inflammatory Syndrome in Adults</classLabel>
<newAxiom>'Multisystem Inflammatory Syndrome in Adults' SubClassOf 'Syndrome'</newAxiom>
<newAxiom>'Multisystem Inflammatory Syndrome in Adults' SubClassOf 'Infectious Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178503</classIRI>
<classLabel>Time from COVID-19 Symptom Onset to Hospitalization</classLabel>
<newAxiom>'Time from COVID-19 Symptom Onset to Hospitalization' SubClassOf 'Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178504</classIRI>
<classLabel>Time from COVID-19 Diagnosis to Hospitalization</classLabel>
<newAxiom>'Time from COVID-19 Diagnosis to Hospitalization' SubClassOf 'Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178500</classIRI>
<classLabel>Probable Case Based on Vital Records</classLabel>
<newAxiom>'Probable Case Based on Vital Records' SubClassOf 'Probable Case'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178509</classIRI>
<classLabel>U2AF1 Gene Mutation Negative</classLabel>
<newAxiom>'U2AF1 Gene Mutation Negative' SubClassOf 'Wildtype Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178505</classIRI>
<classLabel>60 Months</classLabel>
<newAxiom>'60 Months' SubClassOf 'Period'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178506</classIRI>
<classLabel>Central Nervous System SMARCB1/INI1-Deficient Tumor</classLabel>
<newAxiom>'Central Nervous System SMARCB1/INI1-Deficient Tumor' EquivalentTo 'Primary Central Nervous System Neoplasm' and ('Disease_Has_Molecular_Abnormality' some 'SMARCB1 Gene Mutation') and ('Disease_Has_Finding' some 'Loss of INI 1 Protein Expression') and ('Disease_Mapped_To_Gene' some 'SMARCB1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178507</classIRI>
<classLabel>Desmoplastic Myxoid Tumor, SMARCB1-Mutant</classLabel>
<newAxiom>'Desmoplastic Myxoid Tumor, SMARCB1-Mutant' EquivalentTo 'Central Nervous System SMARCB1/INI1-Deficient Tumor' and 'Pineal Region Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Pineal Gland') and ('Disease_Has_Abnormal_Cell' some 'Neoplastic Spindle Cell') and ('Disease_Has_Abnormal_Cell' some 'Neoplastic Epithelioid Cell') and ('Disease_Has_Finding' some 'Desmoplastic Stroma Formation') and ('Disease_Has_Finding' some 'Low Grade Lesion') and ('Disease_Has_Finding' some 'Myxoid Changes Present')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178508</classIRI>
<classLabel>SRSF2 Gene Mutation Negative</classLabel>
<newAxiom>'SRSF2 Gene Mutation Negative' SubClassOf 'Wildtype Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178596</classIRI>
<classLabel>SKP1 Gene</classLabel>
<newAxiom>'SKP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Regulation'</newAxiom>
<newAxiom>'SKP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Signal Transduction'</newAxiom>
<newAxiom>'SKP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Ubiquitinated Protein Degradation'</newAxiom>
<newAxiom>'SKP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell Cycle Progression'</newAxiom>
<newAxiom>'SKP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein-Protein Interaction'</newAxiom>
<newAxiom>'SKP1 Gene' SubClassOf 'Regulatory Gene'</newAxiom>
<newAxiom>'SKP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Ubiquitination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178597</classIRI>
<classLabel>SKP1 wt Allele</classLabel>
<newAxiom>'SKP1 wt Allele' EquivalentTo 'SKP1 Gene' and ('Gene_Is_Element_In_Pathway' some 'Cell Cycle Pathway') and ('Gene_Is_Element_In_Pathway' some 'Circadian Rhythm Pathway KEGG') and ('Gene_Is_Element_In_Pathway' some 'Ubiquitin-mediated Proteolysis Pathway') and ('Gene_Is_Element_In_Pathway' some 'Salmonella Pathway') and ('Gene_Is_Element_In_Pathway' some 'Oocyte Meiosis Pathway') and ('Gene_Is_Element_In_Pathway' some 'TGF-beta Signaling Pathway KEGG') and ('Gene_Is_Element_In_Pathway' some 'Wnt Signaling Pathway KEGG') and ('Gene_Is_Element_In_Pathway' some 'Shigellosis Pathway') and ('Gene_In_Chromosomal_Location' some '5q31.1')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178598</classIRI>
<classLabel>S-Phase Kinase-Associated Protein 1</classLabel>
<newAxiom>'S-Phase Kinase-Associated Protein 1' EquivalentTo 'Ubiquitination Regulation Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Cell Cycle Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Circadian Rhythm Pathway KEGG') and ('Gene_Product_Is_Element_In_Pathway' some 'Ubiquitin-mediated Proteolysis Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Salmonella Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Oocyte Meiosis Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'TGF-beta Signaling Pathway KEGG') and ('Gene_Product_Is_Element_In_Pathway' some 'Wnt Signaling Pathway KEGG') and ('Gene_Product_Is_Element_In_Pathway' some 'Shigellosis Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleus') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytosol') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'BTB/POZ Domain') and ('Gene_Product_Is_Physical_Part_Of' some 'Ubiquitin Protein Ligase') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Signal Transduction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Protein Interaction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Regulation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Ubiquitination') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Ubiquitinated Protein Degradation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Cycle Progression') and ('Gene_Product_Encoded_By_Gene' some 'SKP1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178599</classIRI>
<classLabel>Fibrocartilaginous Mesenchymoma</classLabel>
<newAxiom>'Fibrocartilaginous Mesenchymoma' EquivalentTo 'Intermediate Bone Neoplasm' and ('Disease_Has_Abnormal_Cell' some 'Neoplastic Connective and Soft Tissue Spindle Cell') and ('Disease_Has_Finding' some 'Cartilaginous Component Present')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178589</classIRI>
<classLabel>Anti-CD19/CD3 Bispecific Antibody GNR-084</classLabel>
<newAxiom>'Anti-CD19/CD3 Bispecific Antibody GNR-084' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-CD19/CD3 Bispecific Antibody GNR-084' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178585</classIRI>
<classLabel>EGFR Inhibitor XZP-5809</classLabel>
<newAxiom>'EGFR Inhibitor XZP-5809' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'EGFR Inhibitor XZP-5809' SubClassOf 'Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178586</classIRI>
<classLabel>Serine Racemase</classLabel>
<newAxiom>'Serine Racemase' EquivalentTo 'Isomerase' and 'Lyase' and ('Gene_Product_Is_Element_In_Pathway' some 'Glycine, Serine and Threonine Metabolism Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytosol') and ('Gene_Product_Expressed_In_Tissue' some 'Brain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Metabolic Process') and ('Gene_Product_Encoded_By_Gene' some 'SRR Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178587</classIRI>
<classLabel>Allogeneic Anti-CD5-IL-15/IL-15sushi-safety Switch CAR T Cells</classLabel>
<newAxiom>'Allogeneic Anti-CD5-IL-15/IL-15sushi-safety Switch CAR T Cells' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Allogeneic Anti-CD5-IL-15/IL-15sushi-safety Switch CAR T Cells' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Allogeneic Anti-CD5-IL-15/IL-15sushi-safety Switch CAR T Cells' SubClassOf 'Therapeutic Allogeneic Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178588</classIRI>
<classLabel>Autologous Anti-CD19 CAR-T Cells GC019F</classLabel>
<newAxiom>'Autologous Anti-CD19 CAR-T Cells GC019F' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Autologous Anti-CD19 CAR-T Cells GC019F' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous Anti-CD19 CAR-T Cells GC019F' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178592</classIRI>
<classLabel>OCIA Domain-Containing Protein 1</classLabel>
<newAxiom>'OCIA Domain-Containing Protein 1' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Endosome'</newAxiom>
<newAxiom>'OCIA Domain-Containing Protein 1' SubClassOf 'Signaling Protein'</newAxiom>
<newAxiom>'OCIA Domain-Containing Protein 1' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'OCIAD1 Gene'</newAxiom>
<newAxiom>'OCIA Domain-Containing Protein 1' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Signal Transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178593</classIRI>
<classLabel>UBE2I Gene</classLabel>
<newAxiom>'UBE2I Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Post-Translational Modification'</newAxiom>
<newAxiom>'UBE2I Gene' SubClassOf 'Transferase Gene'</newAxiom>
<newAxiom>'UBE2I Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Chromosome Segregation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178594</classIRI>
<classLabel>UBE2I wt Allele</classLabel>
<newAxiom>'UBE2I wt Allele' EquivalentTo 'UBE2I Gene' and ('Gene_Is_Element_In_Pathway' some 'Ubiquitin-mediated Proteolysis Pathway') and ('Gene_Is_Element_In_Pathway' some 'Coregulation Pathway for Androgen Receptor Activity') and ('Gene_Is_Element_In_Pathway' some 'HDAC Class I Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'HDAC Class II Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'RANBP2-Mediated Sumoylation Transcription Regulation Pathway') and ('Gene_In_Chromosomal_Location' some '16p13.3')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178595</classIRI>
<classLabel>SUMO-Conjugating Enzyme UBC9</classLabel>
<newAxiom>'SUMO-Conjugating Enzyme UBC9' EquivalentTo 'Acyltransferase' and ('Gene_Product_Is_Element_In_Pathway' some 'Ubiquitin-mediated Proteolysis Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Coregulation Pathway for Androgen Receptor Activity') and ('Gene_Product_Is_Element_In_Pathway' some 'HDAC Class I Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'HDAC Class II Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'RANBP2-Mediated Sumoylation Transcription Regulation Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleus') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoplasm') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'UBC Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Post-Translational Modification') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Chromosome Segregation') and ('Gene_Product_Encoded_By_Gene' some 'UBE2I Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178590</classIRI>
<classLabel>OCIAD1 Gene</classLabel>
<newAxiom>'OCIAD1 Gene' SubClassOf 'Signaling Pathway Gene'</newAxiom>
<newAxiom>'OCIAD1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Signal Transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178591</classIRI>
<classLabel>OCIAD1 wt Allele</classLabel>
<newAxiom>'OCIAD1 wt Allele' SubClassOf 'OCIAD1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178578</classIRI>
<classLabel>TRK Inhibitor VC004</classLabel>
<newAxiom>'TRK Inhibitor VC004' SubClassOf 'TRK Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178579</classIRI>
<classLabel>SLC6A19 Gene</classLabel>
<newAxiom>'SLC6A19 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transmembrane Transport'</newAxiom>
<newAxiom>'SLC6A19 Gene' SubClassOf 'Transport Protein Gene'</newAxiom>
<newAxiom>'SLC6A19 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Ion Transport Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178574</classIRI>
<classLabel>SUMO-Activating Enzyme</classLabel>
<newAxiom>'SUMO-Activating Enzyme' SubClassOf 'Protein or Riboprotein Complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178575</classIRI>
<classLabel>BCMA-specific Universal CAR-expressing T-lymphocytes LCAR-BCX</classLabel>
<newAxiom>'BCMA-specific Universal CAR-expressing T-lymphocytes LCAR-BCX' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'BCMA-specific Universal CAR-expressing T-lymphocytes LCAR-BCX' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178576</classIRI>
<classLabel>Anti-TROP2 Monoclonal Antibody-Tub196 Conjugate JS108</classLabel>
<newAxiom>'Anti-TROP2 Monoclonal Antibody-Tub196 Conjugate JS108' SubClassOf 'Antineoplastic Antibody-Drug Conjugate'</newAxiom>
<newAxiom>'Anti-TROP2 Monoclonal Antibody-Tub196 Conjugate JS108' SubClassOf 'Immunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178577</classIRI>
<classLabel>Anti-CD19/CD3 Bispecific Antibody TNB-486</classLabel>
<newAxiom>'Anti-CD19/CD3 Bispecific Antibody TNB-486' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-CD19/CD3 Bispecific Antibody TNB-486' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178581</classIRI>
<classLabel>Gallium Ga 68-ICAM-1pep</classLabel>
<newAxiom>'Gallium Ga 68-ICAM-1pep' SubClassOf 'Radioconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178582</classIRI>
<classLabel>Sodium-Dependent Neutral Amino Acid Transporter B(0)AT1</classLabel>
<newAxiom>'Sodium-Dependent Neutral Amino Acid Transporter B(0)AT1' EquivalentTo 'Transport Protein' and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Solute Carrier Family') and ('Gene_Product_Has_Biochemical_Function' some 'Amino Acid Transporter') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transmembrane Transport') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Ion Transport Process') and ('Gene_Product_Encoded_By_Gene' some 'SLC6A19 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178583</classIRI>
<classLabel>SRR Gene</classLabel>
<newAxiom>'SRR Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Metabolic Process'</newAxiom>
<newAxiom>'SRR Gene' SubClassOf 'Lyase Gene'</newAxiom>
<newAxiom>'SRR Gene' SubClassOf 'Isomerase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178584</classIRI>
<classLabel>SRR wt Allele</classLabel>
<newAxiom>'SRR wt Allele' EquivalentTo 'SRR Gene' and ('Gene_Is_Element_In_Pathway' some 'Glycine, Serine and Threonine Metabolism Pathway') and ('Gene_In_Chromosomal_Location' some '17p13.3')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178580</classIRI>
<classLabel>SLC6A19 wt Allele</classLabel>
<newAxiom>'SLC6A19 wt Allele' SubClassOf 'SLC6A19 Gene'</newAxiom>
<newAxiom>'SLC6A19 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '5p15.33'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178567</classIRI>
<classLabel>Membrane Attack Complex</classLabel>
<newAxiom>'Membrane Attack Complex' SubClassOf 'Protein or Riboprotein Complex'</newAxiom>
<newAxiom>'Membrane Attack Complex' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Complement-Dependent Cytotoxicity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178568</classIRI>
<classLabel>MicroRNA 181a</classLabel>
<newAxiom>'MicroRNA 181a' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'MIR181A2 Gene'</newAxiom>
<newAxiom>'MicroRNA 181a' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'MIR181A1 Gene'</newAxiom>
<newAxiom>'MicroRNA 181a' SubClassOf 'MicroRNA 181'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178569</classIRI>
<classLabel>Adenosine A2A Receptor Antagonist DZD2269</classLabel>
<newAxiom>'Adenosine A2A Receptor Antagonist DZD2269' SubClassOf 'Immunostimulant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178563</classIRI>
<classLabel>Conventional Chordoma</classLabel>
<newAxiom>'Conventional Chordoma' EquivalentTo 'Chordoma' and ('Disease_Has_Abnormal_Cell' some 'Physaliphorous Cell') and ('Disease_Has_Abnormal_Cell' some 'Malignant Epithelioid Cell') and ('Disease_Has_Finding' some 'Lobulated Growth Pattern') and ('Disease_Has_Finding' some 'Myxoid Stroma Formation') and ('Disease_Excludes_Finding' some 'Sarcomatous Component Present')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178564</classIRI>
<classLabel>Cardiac Fibrosis</classLabel>
<newAxiom>'Cardiac Fibrosis' SubClassOf 'Fibrosis'</newAxiom>
<newAxiom>'Cardiac Fibrosis' SubClassOf 'Non-Neoplastic Heart Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178565</classIRI>
<classLabel>Cancer-Associated Pain</classLabel>
<newAxiom>'Cancer-Associated Pain' SubClassOf 'Pain'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178566</classIRI>
<classLabel>Pyruvate Dehydrogenase Kinase</classLabel>
<newAxiom>'Pyruvate Dehydrogenase Kinase' SubClassOf 'Kinase'</newAxiom>
<newAxiom>'Pyruvate Dehydrogenase Kinase' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Carbohydrate Metabolic Process'</newAxiom>
<newAxiom>'Pyruvate Dehydrogenase Kinase' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Serine/Threonine Phosphorylation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178570</classIRI>
<classLabel>IFNB1 Gene</classLabel>
<newAxiom>'IFNB1 Gene' SubClassOf 'Signaling Pathway Gene'</newAxiom>
<newAxiom>'IFNB1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Antitumor Response'</newAxiom>
<newAxiom>'IFNB1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'B Cell Proliferation'</newAxiom>
<newAxiom>'IFNB1 Gene' SubClassOf 'Cytokine Gene'</newAxiom>
<newAxiom>'IFNB1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Antimicrobial Effect'</newAxiom>
<newAxiom>'IFNB1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Humoral Immunity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178571</classIRI>
<classLabel>IFNB1 wt Allele</classLabel>
<newAxiom>'IFNB1 wt Allele' EquivalentTo 'IFNB1 Gene' and ('Gene_Is_Element_In_Pathway' some 'Human Cytomegalovirus Infection Pathway') and ('Gene_Is_Element_In_Pathway' some 'Natural Killer Cell-Mediated Cytotoxicity Pathway') and ('Gene_Is_Element_In_Pathway' some 'Cytokine-Cytokine Receptor Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Cytosolic DNA-Sensing Pathway') and ('Gene_Is_Element_In_Pathway' some 'Toll-Like Receptor Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'NOD-Like Receptor Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'RIG-I-Like Receptor Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Jak-STAT Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Chagas Disease Pathway') and ('Gene_Is_Element_In_Pathway' some 'Regulation of Nuclear SMAD2/3 Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Shigellosis Pathway') and ('Gene_In_Chromosomal_Location' some '9p21.3')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178572</classIRI>
<classLabel>Buffer TCL</classLabel>
<newAxiom>'Buffer TCL' SubClassOf 'Buffer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178573</classIRI>
<classLabel>NP40 Lysis Buffer</classLabel>
<newAxiom>'NP40 Lysis Buffer' SubClassOf 'Buffer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178677</classIRI>
<classLabel>Refractory High Grade Ovarian Serous Adenocarcinoma</classLabel>
<newAxiom>'Refractory High Grade Ovarian Serous Adenocarcinoma' EquivalentTo 'High Grade Ovarian Serous Adenocarcinoma' and 'Refractory Ovarian Serous Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178678</classIRI>
<classLabel>Refractory Low Grade Fallopian Tube Serous Adenocarcinoma</classLabel>
<newAxiom>'Refractory Low Grade Fallopian Tube Serous Adenocarcinoma' EquivalentTo 'Low Grade Fallopian Tube Serous Adenocarcinoma' and 'Refractory Fallopian Tube Serous Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178679</classIRI>
<classLabel>Refractory Low Grade Ovarian Serous Adenocarcinoma</classLabel>
<newAxiom>'Refractory Low Grade Ovarian Serous Adenocarcinoma' EquivalentTo 'Low Grade Ovarian Serous Adenocarcinoma' and 'Refractory Ovarian Serous Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178673</classIRI>
<classLabel>Refractory Fallopian Tube Endometrioid Adenocarcinoma</classLabel>
<newAxiom>'Refractory Fallopian Tube Endometrioid Adenocarcinoma' EquivalentTo 'Refractory Fallopian Tube Adenocarcinoma' and 'Fallopian Tube Endometrioid Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178674</classIRI>
<classLabel>Refractory Fallopian Tube Transitional Cell Carcinoma</classLabel>
<newAxiom>'Refractory Fallopian Tube Transitional Cell Carcinoma' EquivalentTo 'Refractory Fallopian Tube Carcinoma' and 'Fallopian Tube Transitional Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178675</classIRI>
<classLabel>Refractory Fallopian Tube Undifferentiated Carcinoma</classLabel>
<newAxiom>'Refractory Fallopian Tube Undifferentiated Carcinoma' EquivalentTo 'Refractory Fallopian Tube Carcinoma' and 'Fallopian Tube Undifferentiated Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178676</classIRI>
<classLabel>Refractory High Grade Fallopian Tube Serous Adenocarcinoma</classLabel>
<newAxiom>'Refractory High Grade Fallopian Tube Serous Adenocarcinoma' EquivalentTo 'High Grade Fallopian Tube Serous Adenocarcinoma' and 'Refractory Fallopian Tube Serous Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178680</classIRI>
<classLabel>Refractory Ovarian Clear Cell Adenocarcinoma</classLabel>
<newAxiom>'Refractory Ovarian Clear Cell Adenocarcinoma' EquivalentTo 'Refractory Ovarian Adenocarcinoma' and 'Ovarian Clear Cell Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178681</classIRI>
<classLabel>Refractory Ovarian Mucinous Adenocarcinoma</classLabel>
<newAxiom>'Refractory Ovarian Mucinous Adenocarcinoma' EquivalentTo 'Refractory Ovarian Adenocarcinoma' and 'Ovarian Mucinous Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178682</classIRI>
<classLabel>Refractory Ovarian Transitional Cell Carcinoma</classLabel>
<newAxiom>'Refractory Ovarian Transitional Cell Carcinoma' EquivalentTo 'Refractory Ovarian Carcinoma' and 'Ovarian Transitional Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178683</classIRI>
<classLabel>Refractory Ovarian Undifferentiated Carcinoma</classLabel>
<newAxiom>'Refractory Ovarian Undifferentiated Carcinoma' EquivalentTo 'Refractory Ovarian Carcinoma' and 'Ovarian Undifferentiated Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178666</classIRI>
<classLabel>IL1RL2 wt Allele</classLabel>
<newAxiom>'IL1RL2 wt Allele' SubClassOf 'IL1RL2 Gene'</newAxiom>
<newAxiom>'IL1RL2 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Cytokine-Cytokine Receptor Signaling Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178667</classIRI>
<classLabel>Interleukin-1 Receptor-Like 2</classLabel>
<newAxiom>'Interleukin-1 Receptor-Like 2' EquivalentTo 'Hydrolase' and 'Cytokine Receptor' and ('Gene_Product_Is_Element_In_Pathway' some 'Cytokine-Cytokine Receptor Signaling Pathway') and ('Gene_Product_Has_Chemical_Classification' some 'Immunoglobulin Family Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Immunoglobulin-Like C2-Type Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Nucleotide Metabolic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Interferon Signaling Process') and ('Gene_Product_Encoded_By_Gene' some 'IL1RL2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178668</classIRI>
<classLabel>Recurrent Fallopian Tube Mucinous Adenocarcinoma</classLabel>
<newAxiom>'Recurrent Fallopian Tube Mucinous Adenocarcinoma' EquivalentTo 'Recurrent Fallopian Tube Adenocarcinoma' and 'Fallopian Tube Mucinous Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178669</classIRI>
<classLabel>Recurrent Ovarian Seromucinous Carcinoma</classLabel>
<newAxiom>'Recurrent Ovarian Seromucinous Carcinoma' EquivalentTo 'Ovarian Seromucinous Carcinoma' and 'Recurrent Ovarian Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178662</classIRI>
<classLabel>CA242 Antigen</classLabel>
<newAxiom>'CA242 Antigen' SubClassOf 'Tumor Antigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178663</classIRI>
<classLabel>KL-6 Antigen</classLabel>
<newAxiom>'KL-6 Antigen' SubClassOf 'Tumor Antigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178664</classIRI>
<classLabel>CT-RCC-1 Antigen</classLabel>
<newAxiom>'CT-RCC-1 Antigen' SubClassOf 'Tumor Antigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178665</classIRI>
<classLabel>IL1RL2 Gene</classLabel>
<newAxiom>'IL1RL2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Nucleotide Metabolic Process'</newAxiom>
<newAxiom>'IL1RL2 Gene' SubClassOf 'Hydrolase Gene'</newAxiom>
<newAxiom>'IL1RL2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Interleukin Signaling Process'</newAxiom>
<newAxiom>'IL1RL2 Gene' SubClassOf 'Cytokine Receptor Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178670</classIRI>
<classLabel>Refractory Fallopian Tube Mucinous Adenocarcinoma</classLabel>
<newAxiom>'Refractory Fallopian Tube Mucinous Adenocarcinoma' EquivalentTo 'Refractory Fallopian Tube Adenocarcinoma' and 'Fallopian Tube Mucinous Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178671</classIRI>
<classLabel>Refractory Ovarian Seromucinous Carcinoma</classLabel>
<newAxiom>'Refractory Ovarian Seromucinous Carcinoma' EquivalentTo 'Refractory Ovarian Carcinoma' and 'Ovarian Seromucinous Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178672</classIRI>
<classLabel>Refractory Fallopian Tube Clear Cell Adenocarcinoma</classLabel>
<newAxiom>'Refractory Fallopian Tube Clear Cell Adenocarcinoma' EquivalentTo 'Refractory Fallopian Tube Adenocarcinoma' and 'Fallopian Tube Clear Cell Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178655</classIRI>
<classLabel>Serum Amyloid A-2 Protein</classLabel>
<newAxiom>'Serum Amyloid A-2 Protein' EquivalentTo 'Immunoprotein' and ('Gene_Product_Has_Chemical_Classification' some 'Circulating Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Expressed_In_Tissue' some 'Plasma') and ('Gene_Product_Has_Biochemical_Function' some 'Serum Amyloid A') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immunity') and ('Gene_Product_Encoded_By_Gene' some 'SAA2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178656</classIRI>
<classLabel>SAA4 Gene</classLabel>
<newAxiom>'SAA4 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immunity'</newAxiom>
<newAxiom>'SAA4 Gene' SubClassOf 'Immunoprotein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178657</classIRI>
<classLabel>SAA4 wt Allele</classLabel>
<newAxiom>'SAA4 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '11p15.1'</newAxiom>
<newAxiom>'SAA4 wt Allele' SubClassOf 'SAA4 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178658</classIRI>
<classLabel>Serum Amyloid A-4 Protein</classLabel>
<newAxiom>'Serum Amyloid A-4 Protein' EquivalentTo 'Immunoprotein' and ('Gene_Product_Has_Chemical_Classification' some 'Circulating Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Expressed_In_Tissue' some 'Plasma') and ('Gene_Product_Has_Biochemical_Function' some 'Serum Amyloid A') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immunity') and ('Gene_Product_Encoded_By_Gene' some 'SAA4 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178651</classIRI>
<classLabel>SAA1 wt Allele</classLabel>
<newAxiom>'SAA1 wt Allele' SubClassOf 'SAA1 Gene'</newAxiom>
<newAxiom>'SAA1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '11p15.1'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178652</classIRI>
<classLabel>Serum Amyloid A-1 Protein</classLabel>
<newAxiom>'Serum Amyloid A-1 Protein' EquivalentTo 'Immunoprotein' and ('Gene_Product_Has_Chemical_Classification' some 'Circulating Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Expressed_In_Tissue' some 'Plasma') and ('Gene_Product_Has_Biochemical_Function' some 'Serum Amyloid A') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immunity') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Heparin Binding') and ('Gene_Product_Encoded_By_Gene' some 'SAA1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178653</classIRI>
<classLabel>SAA2 Gene</classLabel>
<newAxiom>'SAA2 Gene' SubClassOf 'Immunoprotein Gene'</newAxiom>
<newAxiom>'SAA2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immunity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178654</classIRI>
<classLabel>SAA2 wt Allele</classLabel>
<newAxiom>'SAA2 wt Allele' SubClassOf 'SAA2 Gene'</newAxiom>
<newAxiom>'SAA2 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '11p15.1'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178659</classIRI>
<classLabel>HERV-E</classLabel>
<newAxiom>'HERV-E' SubClassOf 'Endogenous Retrovirus'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178660</classIRI>
<classLabel>MG7 Antigen</classLabel>
<newAxiom>'MG7 Antigen' SubClassOf 'Tumor Antigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178661</classIRI>
<classLabel>CA6 Antigen</classLabel>
<newAxiom>'CA6 Antigen' SubClassOf 'Tumor Antigen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178644</classIRI>
<classLabel>C6 Gene</classLabel>
<newAxiom>'C6 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Activation of Membrane Attack Complex'</newAxiom>
<newAxiom>'C6 Gene' SubClassOf 'Complement Component Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178645</classIRI>
<classLabel>C6 wt Allele</classLabel>
<newAxiom>'C6 wt Allele' EquivalentTo 'C6 Gene' and ('Gene_Is_Element_In_Pathway' some 'Prion Disease Pathway') and ('Gene_Is_Element_In_Pathway' some 'Systemic Lupus Erythematosus Pathway') and ('Gene_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_Is_Element_In_Pathway' some 'Amoebiasis Pathway') and ('Gene_In_Chromosomal_Location' some '5p13.1')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178646</classIRI>
<classLabel>Complement Component C6</classLabel>
<newAxiom>'Complement Component C6' EquivalentTo 'Complement Component Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Prion Disease Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Systemic Lupus Erythematosus Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_Product_Is_Element_In_Pathway' some 'Amoebiasis Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'EGF-Like Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Sushi Domain') and ('Gene_Product_Is_Physical_Part_Of' some 'Membrane Attack Complex') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Activation of Membrane Attack Complex') and ('Gene_Product_Encoded_By_Gene' some 'C6 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178647</classIRI>
<classLabel>CFB Gene</classLabel>
<newAxiom>'CFB Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Complement Activation'</newAxiom>
<newAxiom>'CFB Gene' SubClassOf 'Peptidase Gene'</newAxiom>
<newAxiom>'CFB Gene' SubClassOf 'Complement Component Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178640</classIRI>
<classLabel>APCS Gene</classLabel>
<newAxiom>'APCS Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Calcium Binding'</newAxiom>
<newAxiom>'APCS Gene' SubClassOf 'Ligand Binding Protein Gene'</newAxiom>
<newAxiom>'APCS Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Unfolded Protein Response'</newAxiom>
<newAxiom>'APCS Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immune Response Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178641</classIRI>
<classLabel>APCS wt Allele</classLabel>
<newAxiom>'APCS wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '1q23.2'</newAxiom>
<newAxiom>'APCS wt Allele' SubClassOf 'APCS Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178642</classIRI>
<classLabel>Serum Amyloid P-Component</classLabel>
<newAxiom>'Serum Amyloid P-Component' EquivalentTo 'Calcium Binding Protein' and ('Gene_Product_Has_Chemical_Classification' some 'Serum Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Expressed_In_Tissue' some 'Urine') and ('Gene_Product_Expressed_In_Tissue' some 'Serum') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Unfolded Protein Response') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immune Response Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Calcium Binding') and ('Gene_Product_Encoded_By_Gene' some 'APCS Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178643</classIRI>
<classLabel>Nanoparticle SN-38-encapsulated Micelle Formulation SNB-101</classLabel>
<newAxiom>'Nanoparticle SN-38-encapsulated Micelle Formulation SNB-101' SubClassOf 'Topoisomerase-I Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178648</classIRI>
<classLabel>CFB wt Allele</classLabel>
<newAxiom>'CFB wt Allele' EquivalentTo 'CFB Gene' and ('Gene_Is_Element_In_Pathway' some 'Alternative Complement Pathway') and ('Gene_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_In_Chromosomal_Location' some '6p21.33')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178649</classIRI>
<classLabel>Complement Factor B</classLabel>
<newAxiom>'Complement Factor B' EquivalentTo 'Serine Protease' and 'Complement Component Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Alternative Complement Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Sushi Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Complement Activation') and ('Gene_Product_Encoded_By_Gene' some 'CFB Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178650</classIRI>
<classLabel>SAA1 Gene</classLabel>
<newAxiom>'SAA1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Heparin Binding'</newAxiom>
<newAxiom>'SAA1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immunity'</newAxiom>
<newAxiom>'SAA1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'G Protein-Coupled Receptor Signaling'</newAxiom>
<newAxiom>'SAA1 Gene' SubClassOf 'Immunoprotein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178633</classIRI>
<classLabel>C9 Gene</classLabel>
<newAxiom>'C9 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Activation of Membrane Attack Complex'</newAxiom>
<newAxiom>'C9 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Complement-Dependent Cytotoxicity'</newAxiom>
<newAxiom>'C9 Gene' SubClassOf 'Complement Component Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178634</classIRI>
<classLabel>C9 wt Allele</classLabel>
<newAxiom>'C9 wt Allele' EquivalentTo 'C9 Gene' and ('Gene_Is_Element_In_Pathway' some 'Prion Disease Pathway') and ('Gene_Is_Element_In_Pathway' some 'Systemic Lupus Erythematosus Pathway') and ('Gene_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_Is_Element_In_Pathway' some 'Amoebiasis Pathway') and ('Gene_In_Chromosomal_Location' some '5p13.1')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178635</classIRI>
<classLabel>Complement Component C9</classLabel>
<newAxiom>'Complement Component C9' EquivalentTo 'Complement Component Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Prion Disease Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Systemic Lupus Erythematosus Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_Product_Is_Element_In_Pathway' some 'Amoebiasis Pathway') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'EGF-Like Domain') and ('Gene_Product_Is_Physical_Part_Of' some 'Membrane Attack Complex') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Complement-Dependent Cytotoxicity') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Activation of Membrane Attack Complex') and ('Gene_Product_Encoded_By_Gene' some 'C9 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178636</classIRI>
<classLabel>W_pro1 Cancer Vaccine</classLabel>
<newAxiom>'W_pro1 Cancer Vaccine' SubClassOf 'DNA Vaccine'</newAxiom>
<newAxiom>'W_pro1 Cancer Vaccine' SubClassOf 'Antineoplastic Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178630</classIRI>
<classLabel>Limit or Avoid Public Places</classLabel>
<newAxiom>'Limit or Avoid Public Places' SubClassOf 'Social Distancing'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178631</classIRI>
<classLabel>Limit Gatherings to Cohabitants</classLabel>
<newAxiom>'Limit Gatherings to Cohabitants' SubClassOf 'Social Distancing'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178632</classIRI>
<classLabel>Covering Cough or Sneeze</classLabel>
<newAxiom>'Covering Cough or Sneeze' SubClassOf 'Personal Behavior'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178637</classIRI>
<classLabel>IL1RAP Gene</classLabel>
<newAxiom>'IL1RAP Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Interleukin Signaling Process'</newAxiom>
<newAxiom>'IL1RAP Gene' SubClassOf 'Adaptor Signaling Protein Gene'</newAxiom>
<newAxiom>'IL1RAP Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Nucleotide Metabolic Process'</newAxiom>
<newAxiom>'IL1RAP Gene' SubClassOf 'Hydrolase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178638</classIRI>
<classLabel>Interleukin-1 Receptor Accessory Protein</classLabel>
<newAxiom>'Interleukin-1 Receptor Accessory Protein' EquivalentTo 'Hydrolase' and 'Adaptor Signaling Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'MAPK Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Cytokine-Cytokine Receptor Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'IL1-Mediated Signaling Pathway') and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Chemical_Classification' some 'Immunoglobulin Family Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Immunoglobulin-Like C2-Type Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Nucleotide Metabolic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Interferon Signaling Process') and ('Gene_Product_Encoded_By_Gene' some 'IL1RAP Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178639</classIRI>
<classLabel>IL1RAP wt Allele</classLabel>
<newAxiom>'IL1RAP wt Allele' EquivalentTo 'IL1RAP Gene' and ('Gene_Is_Element_In_Pathway' some 'MAPK Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Cytokine-Cytokine Receptor Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'IL1-Mediated Signaling Pathway') and ('Gene_In_Chromosomal_Location' some '3q28')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178622</classIRI>
<classLabel>Worried about Being Unable to Pay Bills</classLabel>
<newAxiom>'Worried about Being Unable to Pay Bills' SubClassOf 'Worry Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178623</classIRI>
<classLabel>Worried about Not Getting Good Medical Care if Sick</classLabel>
<newAxiom>'Worried about Not Getting Good Medical Care if Sick' SubClassOf 'Worry Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178624</classIRI>
<classLabel>Feeling of Being Treated Differently</classLabel>
<newAxiom>'Feeling of Being Treated Differently' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178625</classIRI>
<classLabel>Staying Home More than Usual</classLabel>
<newAxiom>'Staying Home More than Usual' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178620</classIRI>
<classLabel>Worried that it will Affect Health</classLabel>
<newAxiom>'Worried that it will Affect Health' SubClassOf 'Worry Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178621</classIRI>
<classLabel>Worried about Working at Home or Taking or Being Asked to Take Sick Leave</classLabel>
<newAxiom>'Worried about Working at Home or Taking or Being Asked to Take Sick Leave' SubClassOf 'Worry Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178626</classIRI>
<classLabel>EGFR Inhibitor XZP-5809 Tartrate</classLabel>
<newAxiom>'EGFR Inhibitor XZP-5809 Tartrate' SubClassOf 'Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor'</newAxiom>
<newAxiom>'EGFR Inhibitor XZP-5809 Tartrate' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178627</classIRI>
<classLabel>Comfortable with Local Government Preparation</classLabel>
<newAxiom>'Comfortable with Local Government Preparation' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178628</classIRI>
<classLabel>Whole Body Magnetic Resonance Imaging</classLabel>
<newAxiom>'Whole Body Magnetic Resonance Imaging' SubClassOf 'Magnetic Resonance Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178629</classIRI>
<classLabel>Limit or Avoid Gatherings Greater than 10 People</classLabel>
<newAxiom>'Limit or Avoid Gatherings Greater than 10 People' SubClassOf 'Social Distancing'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178611</classIRI>
<classLabel>C8B Gene</classLabel>
<newAxiom>'C8B Gene' SubClassOf 'Complement Component Gene'</newAxiom>
<newAxiom>'C8B Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Activation of Membrane Attack Complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178612</classIRI>
<classLabel>C8B wt Allele</classLabel>
<newAxiom>'C8B wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Amoebiasis Pathway'</newAxiom>
<newAxiom>'C8B wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade'</newAxiom>
<newAxiom>'C8B wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Systemic Lupus Erythematosus Pathway'</newAxiom>
<newAxiom>'C8B wt Allele' SubClassOf 'C8B Gene'</newAxiom>
<newAxiom>'C8B wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Prion Disease Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178613</classIRI>
<classLabel>Bone Rosai-Dorfman Disease</classLabel>
<newAxiom>'Bone Rosai-Dorfman Disease' SubClassOf 'Non-Neoplastic Bone Disorder'</newAxiom>
<newAxiom>'Bone Rosai-Dorfman Disease' SubClassOf 'Rosai-Dorfman Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178614</classIRI>
<classLabel>Complement Component C8 Beta Chain</classLabel>
<newAxiom>'Complement Component C8 Beta Chain' EquivalentTo 'Complement Component Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Prion Disease Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Systemic Lupus Erythematosus Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_Product_Is_Element_In_Pathway' some 'Amoebiasis Pathway') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'EGF-Like Domain') and ('Gene_Product_Is_Physical_Part_Of' some 'Membrane Attack Complex') and ('Gene_Product_Is_Physical_Part_Of' some 'Complement Component C8') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Activation of Membrane Attack Complex') and ('Gene_Product_Encoded_By_Gene' some 'C8B Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178610</classIRI>
<classLabel>NCI Cancer Atlas</classLabel>
<newAxiom>'NCI Cancer Atlas' SubClassOf 'Cancer Research'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178619</classIRI>
<classLabel>Complement Component C8</classLabel>
<newAxiom>'Complement Component C8' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Activation of Membrane Attack Complex'</newAxiom>
<newAxiom>'Complement Component C8' SubClassOf 'Protein or Riboprotein Complex'</newAxiom>
<newAxiom>'Complement Component C8' SubClassOf 'Gene_Product_Is_Physical_Part_Of' some 'Membrane Attack Complex'</newAxiom>
<newAxiom>'Complement Component C8' SubClassOf 'Complement Component Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178615</classIRI>
<classLabel>DNAJB1-PRKACA Fusion Kinase Peptide Vaccine</classLabel>
<newAxiom>'DNAJB1-PRKACA Fusion Kinase Peptide Vaccine' SubClassOf 'Antineoplastic Vaccine'</newAxiom>
<newAxiom>'DNAJB1-PRKACA Fusion Kinase Peptide Vaccine' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'T-Cell Activation'</newAxiom>
<newAxiom>'DNAJB1-PRKACA Fusion Kinase Peptide Vaccine' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Immunopotentiation'</newAxiom>
<newAxiom>'DNAJB1-PRKACA Fusion Kinase Peptide Vaccine' SubClassOf 'Chemical_Or_Drug_Has_Mechanism_Of_Action' some 'Antigen Sensitization'</newAxiom>
<newAxiom>'DNAJB1-PRKACA Fusion Kinase Peptide Vaccine' SubClassOf 'Peptide Vaccine'</newAxiom>
<newAxiom>'DNAJB1-PRKACA Fusion Kinase Peptide Vaccine' SubClassOf 'Chemical_Or_Drug_Affects_Cell_Type_Or_Tissue' some 'Cytotoxic T-Lymphocyte'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178616</classIRI>
<classLabel>C8G Gene</classLabel>
<newAxiom>'C8G Gene' SubClassOf 'Complement Component Gene'</newAxiom>
<newAxiom>'C8G Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Activation of Membrane Attack Complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178617</classIRI>
<classLabel>C8G wt Allele</classLabel>
<newAxiom>'C8G wt Allele' EquivalentTo 'C8G Gene' and ('Gene_Is_Element_In_Pathway' some 'Prion Disease Pathway') and ('Gene_Is_Element_In_Pathway' some 'Systemic Lupus Erythematosus Pathway') and ('Gene_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_Is_Element_In_Pathway' some 'Amoebiasis Pathway') and ('Gene_In_Chromosomal_Location' some '9q34.3')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178618</classIRI>
<classLabel>Complement Component C8 Gamma Chain</classLabel>
<newAxiom>'Complement Component C8 Gamma Chain' EquivalentTo 'Complement Component Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Prion Disease Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Systemic Lupus Erythematosus Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_Product_Is_Element_In_Pathway' some 'Amoebiasis Pathway') and ('Gene_Product_Is_Physical_Part_Of' some 'Membrane Attack Complex') and ('Gene_Product_Is_Physical_Part_Of' some 'Complement Component C8') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Activation of Membrane Attack Complex') and ('Gene_Product_Encoded_By_Gene' some 'C8G Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178600</classIRI>
<classLabel>TRAF3IP2 Gene</classLabel>
<newAxiom>'TRAF3IP2 Gene' SubClassOf 'Ubiquitin-Transferase Gene'</newAxiom>
<newAxiom>'TRAF3IP2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Interleukin Signaling Process'</newAxiom>
<newAxiom>'TRAF3IP2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Polyubiquitination'</newAxiom>
<newAxiom>'TRAF3IP2 Gene' SubClassOf 'Adaptor Signaling Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178601</classIRI>
<classLabel>TRAF3IP2 wt Allele</classLabel>
<newAxiom>'TRAF3IP2 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '6p21'</newAxiom>
<newAxiom>'TRAF3IP2 wt Allele' SubClassOf 'TRAF3IP2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178602</classIRI>
<classLabel>E3 Ubiquitin Ligase TRAF3IP2</classLabel>
<newAxiom>'E3 Ubiquitin Ligase TRAF3IP2' EquivalentTo 'E3 Ubiquitin-Protein Transferase' and 'Adaptor Signaling Protein' and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Polyubiquitination') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Interleukin Signaling Process') and ('Gene_Product_Encoded_By_Gene' some 'TRAF3IP2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178603</classIRI>
<classLabel>Poorly Organized and Inadequately Mineralized Bone Present</classLabel>
<newAxiom>'Poorly Organized and Inadequately Mineralized Bone Present' SubClassOf 'Abnormal Tissue Present'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178608</classIRI>
<classLabel>Complement Component C8 Alpha Chain</classLabel>
<newAxiom>'Complement Component C8 Alpha Chain' EquivalentTo 'Complement Component Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Prion Disease Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Systemic Lupus Erythematosus Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade') and ('Gene_Product_Is_Element_In_Pathway' some 'Amoebiasis Pathway') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'EGF-Like Domain') and ('Gene_Product_Is_Physical_Part_Of' some 'Membrane Attack Complex') and ('Gene_Product_Is_Physical_Part_Of' some 'Complement Component C8') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Activation of Membrane Attack Complex') and ('Gene_Product_Encoded_By_Gene' some 'C8A Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178609</classIRI>
<classLabel>Bone Erdheim-Chester Disease</classLabel>
<newAxiom>'Bone Erdheim-Chester Disease' EquivalentTo 'Erdheim-Chester Disease' and 'Bone Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178604</classIRI>
<classLabel>Bone Hibernoma</classLabel>
<newAxiom>'Bone Hibernoma' EquivalentTo 'Bone Lipoma' and 'Hibernoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178605</classIRI>
<classLabel>C8A Gene</classLabel>
<newAxiom>'C8A Gene' SubClassOf 'Complement Component Gene'</newAxiom>
<newAxiom>'C8A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Activation of Membrane Attack Complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178606</classIRI>
<classLabel>C8A wt Allele</classLabel>
<newAxiom>'C8A wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Prion Disease Pathway'</newAxiom>
<newAxiom>'C8A wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Systemic Lupus Erythematosus Pathway'</newAxiom>
<newAxiom>'C8A wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Amoebiasis Pathway'</newAxiom>
<newAxiom>'C8A wt Allele' SubClassOf 'C8A Gene'</newAxiom>
<newAxiom>'C8A wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Complement and Coagulation Cascade'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178607</classIRI>
<classLabel>Bone Langerhans Cell Histiocytosis</classLabel>
<newAxiom>'Bone Langerhans Cell Histiocytosis' EquivalentTo 'Langerhans Cell Histiocytosis' and 'Bone Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178695</classIRI>
<classLabel>APOD wt Allele</classLabel>
<newAxiom>'APOD wt Allele' SubClassOf 'APOD Gene'</newAxiom>
<newAxiom>'APOD wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '3q29'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178696</classIRI>
<classLabel>Apolipoprotein D</classLabel>
<newAxiom>'Apolipoprotein D' EquivalentTo 'Transport Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Is_Physical_Part_Of' some 'Lipoprotein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Lipid Metabolic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Lipid Transport') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cholesterol Homeostasis') and ('Gene_Product_Encoded_By_Gene' some 'APOD Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178697</classIRI>
<classLabel>Platinum-Refractory Malignant Female Reproductive System Neoplasm</classLabel>
<newAxiom>'Platinum-Refractory Malignant Female Reproductive System Neoplasm' EquivalentTo 'Refractory Malignant Female Reproductive System Neoplasm' and ('Disease_Has_Finding' some 'Platinum-Refractory Disease')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178698</classIRI>
<classLabel>Platinum-Refractory Fallopian Tube Carcinoma</classLabel>
<newAxiom>'Platinum-Refractory Fallopian Tube Carcinoma' EquivalentTo 'Refractory Fallopian Tube Carcinoma' and 'Platinum-Refractory Malignant Female Reproductive System Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178688</classIRI>
<classLabel>Refractory Primary Peritoneal Transitional Cell Carcinoma</classLabel>
<newAxiom>'Refractory Primary Peritoneal Transitional Cell Carcinoma' EquivalentTo 'Refractory Primary Peritoneal Carcinoma' and 'Primary Peritoneal Transitional Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178689</classIRI>
<classLabel>Refractory Primary Peritoneal Undifferentiated Carcinoma</classLabel>
<newAxiom>'Refractory Primary Peritoneal Undifferentiated Carcinoma' EquivalentTo 'Refractory Primary Peritoneal Carcinoma' and 'Primary Peritoneal Undifferentiated Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178684</classIRI>
<classLabel>Refractory Primary Peritoneal Clear Cell Adenocarcinoma</classLabel>
<newAxiom>'Refractory Primary Peritoneal Clear Cell Adenocarcinoma' EquivalentTo 'Primary Peritoneal Clear Cell Adenocarcinoma' and 'Refractory Primary Peritoneal Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178685</classIRI>
<classLabel>Refractory Primary Peritoneal Endometrioid Adenocarcinoma</classLabel>
<newAxiom>'Refractory Primary Peritoneal Endometrioid Adenocarcinoma' EquivalentTo 'Primary Peritoneal Endometrioid Adenocarcinoma' and 'Refractory Primary Peritoneal Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178686</classIRI>
<classLabel>Refractory Primary Peritoneal High Grade Serous Adenocarcinoma</classLabel>
<newAxiom>'Refractory Primary Peritoneal High Grade Serous Adenocarcinoma' EquivalentTo 'Primary Peritoneal High Grade Serous Adenocarcinoma' and 'Refractory Primary Peritoneal Serous Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178687</classIRI>
<classLabel>Refractory Primary Peritoneal Low Grade Serous Adenocarcinoma</classLabel>
<newAxiom>'Refractory Primary Peritoneal Low Grade Serous Adenocarcinoma' EquivalentTo 'Primary Peritoneal Low Grade Serous Adenocarcinoma' and 'Refractory Primary Peritoneal Serous Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178691</classIRI>
<classLabel>Platinum-Refractory Disease</classLabel>
<newAxiom>'Platinum-Refractory Disease' SubClassOf 'Disease Response'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178692</classIRI>
<classLabel>CPN1 wt Allele</classLabel>
<newAxiom>'CPN1 wt Allele' SubClassOf 'CPN1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178693</classIRI>
<classLabel>Carboxypeptidase N Catalytic Chain</classLabel>
<newAxiom>'Carboxypeptidase N Catalytic Chain' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Proteolysis'</newAxiom>
<newAxiom>'Carboxypeptidase N Catalytic Chain' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Peptide Metabolism'</newAxiom>
<newAxiom>'Carboxypeptidase N Catalytic Chain' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'CPN1 Gene'</newAxiom>
<newAxiom>'Carboxypeptidase N Catalytic Chain' SubClassOf 'Metallopeptidase'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178694</classIRI>
<classLabel>APOD Gene</classLabel>
<newAxiom>'APOD Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Lipid Metabolic Process'</newAxiom>
<newAxiom>'APOD Gene' SubClassOf 'Transport Protein Gene'</newAxiom>
<newAxiom>'APOD Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Lipid Transport'</newAxiom>
<newAxiom>'APOD Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cholesterol Homeostasis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178690</classIRI>
<classLabel>CPN1 Gene</classLabel>
<newAxiom>'CPN1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Proteolysis'</newAxiom>
<newAxiom>'CPN1 Gene' SubClassOf 'Metallopeptidase Gene'</newAxiom>
<newAxiom>'CPN1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Peptide Metabolism'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178435</classIRI>
<classLabel>Aurora Kinase/FLT3 Inhibitor EP0042</classLabel>
<newAxiom>'Aurora Kinase/FLT3 Inhibitor EP0042' SubClassOf 'Aurora Kinase Inhibitor'</newAxiom>
<newAxiom>'Aurora Kinase/FLT3 Inhibitor EP0042' SubClassOf 'FLT3 Inhibitor'</newAxiom>
<newAxiom>'Aurora Kinase/FLT3 Inhibitor EP0042' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178436</classIRI>
<classLabel>TLR7 Agonist APR003</classLabel>
<newAxiom>'TLR7 Agonist APR003' SubClassOf 'Toll-like Receptor 7 Agonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178437</classIRI>
<classLabel>Mucosal Melanoma of the Female Genital Tract</classLabel>
<newAxiom>'Mucosal Melanoma of the Female Genital Tract' EquivalentTo 'Mucosal Melanoma of the Genitourinary System' and 'Malignant Female Reproductive System Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Female Reproductive System')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178438</classIRI>
<classLabel>Xiang Sha Liu Jun Zi Decoction</classLabel>
<newAxiom>'Xiang Sha Liu Jun Zi Decoction' SubClassOf 'Traditional Chinese Medicine Formulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178431</classIRI>
<classLabel>NR4A3 Gene Rearrangement</classLabel>
<newAxiom>'NR4A3 Gene Rearrangement' SubClassOf 'Gene Rearrangement Abnormality'</newAxiom>
<newAxiom>'NR4A3 Gene Rearrangement' SubClassOf 'Cytogenetic_Abnormality_Involves_Chromosome' some 'Chromosome 9'</newAxiom>
<newAxiom>'NR4A3 Gene Rearrangement' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'NR4A3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178432</classIRI>
<classLabel>Autologous Total Tumor mRNA and CMV-pp65-flLAMP mRNA Loaded Liposome Vaccine</classLabel>
<newAxiom>'Autologous Total Tumor mRNA and CMV-pp65-flLAMP mRNA Loaded Liposome Vaccine' SubClassOf 'mRNA Vaccine'</newAxiom>
<newAxiom>'Autologous Total Tumor mRNA and CMV-pp65-flLAMP mRNA Loaded Liposome Vaccine' SubClassOf 'Antineoplastic Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178433</classIRI>
<classLabel>Allogeneic CD19CAR-CD28-CD3-zeta-expressing T-lymphocytes</classLabel>
<newAxiom>'Allogeneic CD19CAR-CD28-CD3-zeta-expressing T-lymphocytes' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Allogeneic CD19CAR-CD28-CD3-zeta-expressing T-lymphocytes' SubClassOf 'Anti-CD19-targeting CAR-T Cells'</newAxiom>
<newAxiom>'Allogeneic CD19CAR-CD28-CD3-zeta-expressing T-lymphocytes' SubClassOf 'Therapeutic Allogeneic Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178434</classIRI>
<classLabel>Allogeneic CRISPR-edited Anti-CD19 CAR T Cells PBLTT52CAR19</classLabel>
<newAxiom>'Allogeneic CRISPR-edited Anti-CD19 CAR T Cells PBLTT52CAR19' SubClassOf 'Therapeutic Allogeneic Lymphocytes'</newAxiom>
<newAxiom>'Allogeneic CRISPR-edited Anti-CD19 CAR T Cells PBLTT52CAR19' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Allogeneic CRISPR-edited Anti-CD19 CAR T Cells PBLTT52CAR19' SubClassOf 'Anti-CD19-targeting CAR-T Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178439</classIRI>
<classLabel>Anti-MSLN CAR-T Cells LCAR-M23</classLabel>
<newAxiom>'Anti-MSLN CAR-T Cells LCAR-M23' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Anti-MSLN CAR-T Cells LCAR-M23' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178440</classIRI>
<classLabel>A2A/A2B Adenosine Receptor Antagonist INCB106385</classLabel>
<newAxiom>'A2A/A2B Adenosine Receptor Antagonist INCB106385' SubClassOf 'Immunostimulant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178441</classIRI>
<classLabel>Ovarian Melanoma</classLabel>
<newAxiom>'Ovarian Melanoma' EquivalentTo 'Malignant Ovarian Neoplasm' and 'Non-Cutaneous Melanoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178424</classIRI>
<classLabel>Allogeneic CD20 CAR-grafted Gamma Delta T-cells ADI-001</classLabel>
<newAxiom>'Allogeneic CD20 CAR-grafted Gamma Delta T-cells ADI-001' SubClassOf 'CD20-targeting Agent'</newAxiom>
<newAxiom>'Allogeneic CD20 CAR-grafted Gamma Delta T-cells ADI-001' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Allogeneic CD20 CAR-grafted Gamma Delta T-cells ADI-001' SubClassOf 'Therapeutic Allogeneic Lymphocytes'</newAxiom>
<newAxiom>'Allogeneic CD20 CAR-grafted Gamma Delta T-cells ADI-001' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178425</classIRI>
<classLabel>PD-1-positive B-cell Peptide Antigen/MVF IMU-201/Montanide Vaccine</classLabel>
<newAxiom>'PD-1-positive B-cell Peptide Antigen/MVF IMU-201/Montanide Vaccine' SubClassOf 'Peptide Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178426</classIRI>
<classLabel>NTRK-Rearranged Spindle Cell Neoplasm</classLabel>
<newAxiom>'NTRK-Rearranged Spindle Cell Neoplasm' EquivalentTo 'Soft Tissue Tumor of Uncertain Differentiation' and ('Disease_Has_Abnormal_Cell' some 'Neoplastic Connective and Soft Tissue Spindle Cell') and ('Disease_Has_Cytogenetic_Abnormality' some 'NTRK Gene Rearrangement') and ('Disease_Has_Finding' some 'Hyalinized Stroma Formation') and ('Disease_Has_Finding' some 'Monomorphic Cellular Infiltrate') and ('Disease_Has_Finding' some 'S-100-Positive Neoplastic Cells Present') and ('Disease_Has_Finding' some 'CD34-Positive Neoplastic Cells Present')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178427</classIRI>
<classLabel>Influenza Vaccine</classLabel>
<newAxiom>'Influenza Vaccine' SubClassOf 'Viral Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178422</classIRI>
<classLabel>Talc Poudrage</classLabel>
<newAxiom>'Talc Poudrage' SubClassOf 'Therapeutic Thoracoscopic Surgery'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178428</classIRI>
<classLabel>Urbanized Area</classLabel>
<newAxiom>'Urbanized Area' SubClassOf 'Geographic Area'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178429</classIRI>
<classLabel>Urban Cluster</classLabel>
<newAxiom>'Urban Cluster' SubClassOf 'Geographic Area'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178430</classIRI>
<classLabel>Rural Area</classLabel>
<newAxiom>'Rural Area' SubClassOf 'Geographic Area'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178497</classIRI>
<classLabel>Probable Case</classLabel>
<newAxiom>'Probable Case' SubClassOf 'Case Classification'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178498</classIRI>
<classLabel>Probable Case Based on Clinical and Epidemiologic Evidence</classLabel>
<newAxiom>'Probable Case Based on Clinical and Epidemiologic Evidence' SubClassOf 'Probable Case'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178499</classIRI>
<classLabel>Probable Case Based on Laboratory Results and Clinical or Epidemiologic Evidence</classLabel>
<newAxiom>'Probable Case Based on Laboratory Results and Clinical or Epidemiologic Evidence' SubClassOf 'Probable Case'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178486</classIRI>
<classLabel>Autologous Anti-CLL-1-CAR T-lymphocytes KITE-222</classLabel>
<newAxiom>'Autologous Anti-CLL-1-CAR T-lymphocytes KITE-222' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous Anti-CLL-1-CAR T-lymphocytes KITE-222' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Autologous Anti-CLL-1-CAR T-lymphocytes KITE-222' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178487</classIRI>
<classLabel>EWSR1/NFATC2 Fusion Gene</classLabel>
<newAxiom>'EWSR1/NFATC2 Fusion Gene' SubClassOf 'Fusion Gene'</newAxiom>
<newAxiom>'EWSR1/NFATC2 Fusion Gene' SubClassOf 'Gene_Involved_In_Pathogenesis_Of_Disease' some 'Round Cell Sarcoma with EWSR1-NFATC2 Gene Fusion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178488</classIRI>
<classLabel>FUS/NFATC2 Fusion Gene</classLabel>
<newAxiom>'FUS/NFATC2 Fusion Gene' SubClassOf 'Fusion Gene'</newAxiom>
<newAxiom>'FUS/NFATC2 Fusion Gene' SubClassOf 'Gene_Involved_In_Pathogenesis_Of_Disease' some 'Round Cell Sarcoma with FUS-NFATC2 Gene Fusion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178489</classIRI>
<classLabel>EWSR1/NFATC2 Fusion Protein</classLabel>
<newAxiom>'EWSR1/NFATC2 Fusion Protein' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'EWSR1/NFATC2 Fusion Gene'</newAxiom>
<newAxiom>'EWSR1/NFATC2 Fusion Protein' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Activation'</newAxiom>
<newAxiom>'EWSR1/NFATC2 Fusion Protein' SubClassOf 'Fusion Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178493</classIRI>
<classLabel>Central Chondrosarcoma, Grade 3</classLabel>
<newAxiom>'Central Chondrosarcoma, Grade 3' EquivalentTo 'Chondrosarcoma, Grade 3' and ('Disease_Has_Normal_Tissue_Origin' some 'Medullary Bone') and ('Disease_Excludes_Finding' some 'Secondary Lesion')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178494</classIRI>
<classLabel>Secondary Peripheral Chondrosarcoma, Grade 3</classLabel>
<newAxiom>'Secondary Peripheral Chondrosarcoma, Grade 3' EquivalentTo 'Chondrosarcoma, Grade 3' and 'Secondary Peripheral Chondrosarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178495</classIRI>
<classLabel>Microbiota-based Formulation RBX7455</classLabel>
<newAxiom>'Microbiota-based Formulation RBX7455' SubClassOf 'Immunotherapeutic Agent'</newAxiom>
<newAxiom>'Microbiota-based Formulation RBX7455' SubClassOf 'Biological Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178496</classIRI>
<classLabel>Case Classification</classLabel>
<newAxiom>'Case Classification' SubClassOf 'Classification'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178490</classIRI>
<classLabel>FUS/NFATC2 Fusion Protein</classLabel>
<newAxiom>'FUS/NFATC2 Fusion Protein' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'FUS/NFATC2 Fusion Gene'</newAxiom>
<newAxiom>'FUS/NFATC2 Fusion Protein' SubClassOf 'Fusion Protein'</newAxiom>
<newAxiom>'FUS/NFATC2 Fusion Protein' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Activation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178491</classIRI>
<classLabel>Central Chondrosarcoma, Grade 2</classLabel>
<newAxiom>'Central Chondrosarcoma, Grade 2' EquivalentTo 'Chondrosarcoma, Grade 2' and ('Disease_Has_Normal_Tissue_Origin' some 'Medullary Bone') and ('Disease_Excludes_Finding' some 'Secondary Lesion')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178492</classIRI>
<classLabel>Secondary Peripheral Chondrosarcoma, Grade 2</classLabel>
<newAxiom>'Secondary Peripheral Chondrosarcoma, Grade 2' EquivalentTo 'Chondrosarcoma, Grade 2' and 'Secondary Peripheral Chondrosarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178479</classIRI>
<classLabel>Central Chondrosarcoma, Grade 1</classLabel>
<newAxiom>'Central Chondrosarcoma, Grade 1' EquivalentTo 'Central Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1' and 'Chondrosarcoma, Grade 1'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178476</classIRI>
<classLabel>Primary Central Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1</classLabel>
<newAxiom>'Primary Central Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1' EquivalentTo 'Central Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1' and 'Primary Central Chondrosarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178477</classIRI>
<classLabel>Secondary Central Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1</classLabel>
<newAxiom>'Secondary Central Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1' EquivalentTo 'Secondary Central Chondrosarcoma' and 'Central Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178478</classIRI>
<classLabel>Central Atypical Cartilaginous Tumor</classLabel>
<newAxiom>'Central Atypical Cartilaginous Tumor' EquivalentTo 'Central Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1' and 'Atypical Cartilaginous Tumor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178482</classIRI>
<classLabel>Secondary Peripheral Atypical Cartilaginous Tumor</classLabel>
<newAxiom>'Secondary Peripheral Atypical Cartilaginous Tumor' EquivalentTo 'Secondary Peripheral Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1' and 'Atypical Cartilaginous Tumor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178483</classIRI>
<classLabel>Atypical Cartilaginous Tumor</classLabel>
<newAxiom>'Atypical Cartilaginous Tumor' EquivalentTo 'Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1' and ('Disease_Has_Primary_Anatomic_Site' some 'Appendicular Skeleton')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178484</classIRI>
<classLabel>Chondrosarcoma, Grade 1</classLabel>
<newAxiom>'Chondrosarcoma, Grade 1' EquivalentTo 'Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1' and ('Disease_Has_Primary_Anatomic_Site' some 'Axial Skeleton')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178485</classIRI>
<classLabel>Promonocyte to Leukocyte Ratio Measurement</classLabel>
<newAxiom>'Promonocyte to Leukocyte Ratio Measurement' SubClassOf 'Blood Cell Count Ratio Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178480</classIRI>
<classLabel>Secondary Peripheral Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1</classLabel>
<newAxiom>'Secondary Peripheral Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1' EquivalentTo 'Secondary Malignant Neoplasm' and 'Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1' and ('Disease_Has_Normal_Tissue_Origin' some 'Cartilaginous Tissue') and ('Disease_Has_Associated_Disease' some 'Osteochondroma') and ('Disease_Excludes_Normal_Tissue_Origin' some 'Medullary Bone')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178481</classIRI>
<classLabel>Secondary Peripheral Chondrosarcoma, Grade 1</classLabel>
<newAxiom>'Secondary Peripheral Chondrosarcoma, Grade 1' EquivalentTo 'Secondary Peripheral Chondrosarcoma' and 'Secondary Peripheral Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1' and 'Chondrosarcoma, Grade 1'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178468</classIRI>
<classLabel>BCOR ITD Sarcoma</classLabel>
<newAxiom>'BCOR ITD Sarcoma' EquivalentTo 'Sarcoma with BCOR Genetic Alterations' and ('Disease_Has_Molecular_Abnormality' some 'BCOR Final Exon Internal Tandem Duplication')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178469</classIRI>
<classLabel>SHP2 Inhibitor PF-07284892</classLabel>
<newAxiom>'SHP2 Inhibitor PF-07284892' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178464</classIRI>
<classLabel>BCOR Genetic Alteration</classLabel>
<newAxiom>'BCOR Genetic Alteration' SubClassOf 'Genetic Finding'</newAxiom>
<newAxiom>'BCOR Genetic Alteration' SubClassOf 'Positive Laboratory Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178465</classIRI>
<classLabel>Sarcoma with BCOR Genetic Alterations</classLabel>
<newAxiom>'Sarcoma with BCOR Genetic Alterations' EquivalentTo 'Small Cell Sarcoma' and ('Disease_Has_Abnormal_Cell' some 'Malignant Small Round Cell') and ('Disease_Has_Finding' some 'BCOR Genetic Alteration') and ('Disease_Mapped_To_Gene' some 'BCOR Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178466</classIRI>
<classLabel>BCOR-CCNB3 Sarcoma</classLabel>
<newAxiom>'BCOR-CCNB3 Sarcoma' EquivalentTo 'Sarcoma with BCOR Genetic Alterations' and ('Disease_Has_Molecular_Abnormality' some 'BCOR-CCNB3 Fusion Protein Expression') and ('Disease_Has_Cytogenetic_Abnormality' some 'BCOR Gene Rearrangement') and ('Disease_Mapped_To_Gene' some 'BCOR/CCNB3 Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178467</classIRI>
<classLabel>BCOR-CCNB3 Fusion Protein Expression</classLabel>
<newAxiom>'BCOR-CCNB3 Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'BCOR Gene'</newAxiom>
<newAxiom>'BCOR-CCNB3 Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'BCOR/CCNB3 Fusion Gene'</newAxiom>
<newAxiom>'BCOR-CCNB3 Fusion Protein Expression' SubClassOf 'Fusion Protein Expression'</newAxiom>
<newAxiom>'BCOR-CCNB3 Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'CCNB3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178471</classIRI>
<classLabel>EXT1 Gene Mutation</classLabel>
<newAxiom>'EXT1 Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'EXT1 Gene'</newAxiom>
<newAxiom>'EXT1 Gene Mutation' SubClassOf 'Gene Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178472</classIRI>
<classLabel>EXT2 Gene Mutation</classLabel>
<newAxiom>'EXT2 Gene Mutation' SubClassOf 'Gene Variant'</newAxiom>
<newAxiom>'EXT2 Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'EXT2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178473</classIRI>
<classLabel>Central Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1</classLabel>
<newAxiom>'Central Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1' EquivalentTo 'Atypical Cartilaginous Tumor/Chondrosarcoma, Grade 1' and ('Disease_Has_Normal_Tissue_Origin' some 'Medullary Bone')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178474</classIRI>
<classLabel>KAT6 Inhibitor PF-07248144</classLabel>
<newAxiom>'KAT6 Inhibitor PF-07248144' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178470</classIRI>
<classLabel>Genitourinary Syndrome of Menopause</classLabel>
<newAxiom>'Genitourinary Syndrome of Menopause' SubClassOf 'Syndrome'</newAxiom>
<newAxiom>'Genitourinary Syndrome of Menopause' SubClassOf 'Non-Neoplastic Genitourinary System Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178457</classIRI>
<classLabel>EWSR1-NFATC2 Fusion Protein Expression</classLabel>
<newAxiom>'EWSR1-NFATC2 Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'EWSR1 Gene'</newAxiom>
<newAxiom>'EWSR1-NFATC2 Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'EWSR1/NFATC2 Fusion Gene'</newAxiom>
<newAxiom>'EWSR1-NFATC2 Fusion Protein Expression' SubClassOf 'Fusion Protein Expression'</newAxiom>
<newAxiom>'EWSR1-NFATC2 Fusion Protein Expression' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'NFATC2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178458</classIRI>
<classLabel>FUS-NFATC2 Fusion Protein Expression</classLabel>
<newAxiom>'FUS-NFATC2 Fusion Protein Expression' SubClassOf 'Fusion Protein Expression'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178459</classIRI>
<classLabel>Round Cell Sarcoma with EWSR1–non-ETS Fusion</classLabel>
<newAxiom>'Round Cell Sarcoma with EWSR1–non-ETS Fusion' EquivalentTo 'Small Cell Sarcoma' and ('Disease_Has_Abnormal_Cell' some 'Malignant Small Round Cell') and ('Disease_May_Have_Abnormal_Cell' some 'Malignant Mesenchymal Spindle Cell') and ('Disease_Excludes_Molecular_Abnormality' some 'EWSR1-FLI1 Fusion Protein Expression') and ('Disease_Excludes_Molecular_Abnormality' some 'EWSR1-ERG Fusion Protein Expression') and ('Disease_Excludes_Molecular_Abnormality' some 'EWSR1-ETV1 Fusion Protein Expression') and ('Disease_Excludes_Molecular_Abnormality' some 'EWSR1-ETV4 Fusion Protein Expression') and ('Disease_Excludes_Molecular_Abnormality' some 'EWSR1-FEV Fusion Protein Expression') and ('Disease_Excludes_Molecular_Abnormality' some 'FUS-ERG Fusion Protein Expression') and ('Disease_Excludes_Cytogenetic_Abnormality' some 't(11;22)(q24;q12)') and ('Disease_Excludes_Cytogenetic_Abnormality' some 't(21;22)(q22;q12)') and ('Disease_Excludes_Cytogenetic_Abnormality' some 't(7;22)(p22;q12)') and ('Disease_Excludes_Cytogenetic_Abnormality' some 't(17;22)(q21;q12)') and ('Disease_Excludes_Cytogenetic_Abnormality' some 't(16;21)(p11;q22)') and ('Disease_Excludes_Cytogenetic_Abnormality' some 't(2;22)(q33;q12)') and ('Disease_Excludes_Cytogenetic_Abnormality' some 't(1;22)(p36.1;q12)')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178453</classIRI>
<classLabel>Mucosal Melanoma of the Urinary System</classLabel>
<newAxiom>'Mucosal Melanoma of the Urinary System' EquivalentTo 'Mucosal Melanoma of the Genitourinary System' and 'Malignant Urinary System Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Urinary System')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178454</classIRI>
<classLabel>DHODH Inhibitor JNJ-74856665</classLabel>
<newAxiom>'DHODH Inhibitor JNJ-74856665' SubClassOf 'Dihydroorotate Dehydrogenase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178455</classIRI>
<classLabel>Allogeneic Natural Killer Cells PB103</classLabel>
<newAxiom>'Allogeneic Natural Killer Cells PB103' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Allogeneic Natural Killer Cells PB103' SubClassOf 'Therapeutic Allogeneic Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178456</classIRI>
<classLabel>5-Carbon C 13-labeled Glutamine</classLabel>
<newAxiom>'5-Carbon C 13-labeled Glutamine' SubClassOf 'Radioconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178460</classIRI>
<classLabel>Round Cell Sarcoma with EWSR1-NFATC2 Gene Fusion</classLabel>
<newAxiom>'Round Cell Sarcoma with EWSR1-NFATC2 Gene Fusion' EquivalentTo 'Round Cell Sarcoma with EWSR1–non-ETS Fusion' and ('Disease_Has_Molecular_Abnormality' some 'EWSR1-NFATC2 Fusion Protein Expression') and ('Disease_Has_Cytogenetic_Abnormality' some 'EWSR1 Gene Rearrangement') and ('Disease_Mapped_To_Gene' some 'EWSR1/NFATC2 Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178461</classIRI>
<classLabel>Round Cell Sarcoma with EWSR1-PATZ1 Gene Fusion</classLabel>
<newAxiom>'Round Cell Sarcoma with EWSR1-PATZ1 Gene Fusion' EquivalentTo 'Round Cell Sarcoma with EWSR1–non-ETS Fusion' and ('Disease_Has_Molecular_Abnormality' some 'EWSR1-PATZ1 Fusion Protein Expression') and ('Disease_Has_Cytogenetic_Abnormality' some 'EWSR1 Gene Rearrangement') and ('Disease_Mapped_To_Gene' some 'EWSR1/PATZ1 Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178462</classIRI>
<classLabel>Round Cell Sarcoma with FUS-NFATC2 Gene Fusion</classLabel>
<newAxiom>'Round Cell Sarcoma with FUS-NFATC2 Gene Fusion' EquivalentTo 'Round Cell Sarcoma with EWSR1–non-ETS Fusion' and ('Disease_Has_Molecular_Abnormality' some 'FUS-NFATC2 Fusion Protein Expression') and ('Disease_Has_Cytogenetic_Abnormality' some 'FUS Gene Rearrangement') and ('Disease_Mapped_To_Gene' some 'FUS/NFATC2 Fusion Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178463</classIRI>
<classLabel>CDK9 Inhibitor KB-0742</classLabel>
<newAxiom>'CDK9 Inhibitor KB-0742' SubClassOf 'Chemical_Or_Drug_Affects_Gene_Product' some 'Cyclin-Dependent Kinase'</newAxiom>
<newAxiom>'CDK9 Inhibitor KB-0742' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Protein Phosphorylation Inhibition'</newAxiom>
<newAxiom>'CDK9 Inhibitor KB-0742' SubClassOf 'Cyclin-Dependent Kinase Inhibitor'</newAxiom>
<newAxiom>'CDK9 Inhibitor KB-0742' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'CDK9 Inhibitor KB-0742' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Positive Regulation of Apoptosis'</newAxiom>
<newAxiom>'CDK9 Inhibitor KB-0742' SubClassOf 'Chemical_Or_Drug_Has_Mechanism_Of_Action' some 'Enzyme Inhibition'</newAxiom>
<newAxiom>'CDK9 Inhibitor KB-0742' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Gene Regulation Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178446</classIRI>
<classLabel>Anti-EGFR/c-Met Bispecific Antibody CKD-702</classLabel>
<newAxiom>'Anti-EGFR/c-Met Bispecific Antibody CKD-702' SubClassOf 'Bispecific Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178447</classIRI>
<classLabel>Autologous Neoantigen-specific T-lymphocytes GEN-011</classLabel>
<newAxiom>'Autologous Neoantigen-specific T-lymphocytes GEN-011' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous Neoantigen-specific T-lymphocytes GEN-011' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178448</classIRI>
<classLabel>Anti-CD19/CD3/PD-L1/4-1BB Tetra-specific Antibody GNC-038</classLabel>
<newAxiom>'Anti-CD19/CD3/PD-L1/4-1BB Tetra-specific Antibody GNC-038' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178449</classIRI>
<classLabel>Anti-PD-1/CTLA-4 Bispecific Antibody SI-B003</classLabel>
<newAxiom>'Anti-PD-1/CTLA-4 Bispecific Antibody SI-B003' SubClassOf 'Immune Checkpoint Inhibitor'</newAxiom>
<newAxiom>'Anti-PD-1/CTLA-4 Bispecific Antibody SI-B003' SubClassOf 'Bispecific Monoclonal Antibody'</newAxiom>
<newAxiom>'Anti-PD-1/CTLA-4 Bispecific Antibody SI-B003' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178442</classIRI>
<classLabel>Lactobacillus bulgaricus/Bifidobacterium longum/Streptococcus thermophilus-based Probiotic Supplement</classLabel>
<newAxiom>'Lactobacillus bulgaricus/Bifidobacterium longum/Streptococcus thermophilus-based Probiotic Supplement' SubClassOf 'Dietary Supplement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178443</classIRI>
<classLabel>Mucosal Melanoma of the Genitourinary System</classLabel>
<newAxiom>'Mucosal Melanoma of the Genitourinary System' EquivalentTo 'Mucosal Melanoma' and 'Malignant Genitourinary System Neoplasm' and ('Disease_Has_Primary_Anatomic_Site' some 'Genitourinary System')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178444</classIRI>
<classLabel>Montmorillonite</classLabel>
<newAxiom>'Montmorillonite' SubClassOf 'Antidiarrheal Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178445</classIRI>
<classLabel>Autologous MG7-pulsed Dendritic Cell Vaccine</classLabel>
<newAxiom>'Autologous MG7-pulsed Dendritic Cell Vaccine' SubClassOf 'Therapeutic Autologous Dendritic Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178450</classIRI>
<classLabel>Memorial Sloan-Kettering Cancer Center/Motzer Score for Metastatic Renal Cell Carcinoma</classLabel>
<newAxiom>'Memorial Sloan-Kettering Cancer Center/Motzer Score for Metastatic Renal Cell Carcinoma' SubClassOf 'Predictive Cancer Model'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178451</classIRI>
<classLabel>Fermented Soybean Extract MS-20</classLabel>
<newAxiom>'Fermented Soybean Extract MS-20' SubClassOf 'Dietary Supplement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178452</classIRI>
<classLabel>Autologous Anti-CD19/CD20 CAR-T Cells EXP039</classLabel>
<newAxiom>'Autologous Anti-CD19/CD20 CAR-T Cells EXP039' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous Anti-CD19/CD20 CAR-T Cells EXP039' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Autologous Anti-CD19/CD20 CAR-T Cells EXP039' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179200</classIRI>
<classLabel>CDK7 Inhibitor XL102</classLabel>
<newAxiom>'CDK7 Inhibitor XL102' SubClassOf 'Cyclin-Dependent Kinase Inhibitor'</newAxiom>
<newAxiom>'CDK7 Inhibitor XL102' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179190</classIRI>
<classLabel>Diastolic Hypotension</classLabel>
<newAxiom>'Diastolic Hypotension' SubClassOf 'Hypotension'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179192</classIRI>
<classLabel>Injectable Product-Related Reaction</classLabel>
<newAxiom>'Injectable Product-Related Reaction' SubClassOf 'Side Effect'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179191</classIRI>
<classLabel>Hypotensive Shock</classLabel>
<newAxiom>'Hypotensive Shock' SubClassOf 'Shock'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179198</classIRI>
<classLabel>Electronically Activated Recording</classLabel>
<newAxiom>'Electronically Activated Recording' SubClassOf 'Healthcare Activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179197</classIRI>
<classLabel>Cancer-Associated Anorexia</classLabel>
<newAxiom>'Cancer-Associated Anorexia' SubClassOf 'Anorexia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179199</classIRI>
<classLabel>Omacetaxine</classLabel>
<newAxiom>'Omacetaxine' EquivalentTo 'Antineoplastic Plant Product' and 'Differentiation Inducer' and ('Chemical_Or_Drug_Has_Mechanism_Of_Action' some 'Ribosomal Function Inhibition') and ('Chemical_Or_Drug_Has_Physiologic_Effect' some 'Apoptosis') and ('Chemical_Or_Drug_Has_Physiologic_Effect' some 'Translational Repression') and ('Chemical_Or_Drug_Has_Physiologic_Effect' some 'Positive Regulation of Cell Differentiation') and ('Chemical_Or_Drug_Affects_Cell_Type_Or_Tissue' some 'Ribosome')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179194</classIRI>
<classLabel>Concentrate and Solvent for Intravesical Solution</classLabel>
<newAxiom>'Concentrate and Solvent for Intravesical Solution' SubClassOf 'Combined Dosage Form'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179193</classIRI>
<classLabel>Reactogenicity</classLabel>
<newAxiom>'Reactogenicity' SubClassOf 'Adverse Reaction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179196</classIRI>
<classLabel>Anti-EGFR/LGR5 Bispecific Antibody MCLA-158</classLabel>
<newAxiom>'Anti-EGFR/LGR5 Bispecific Antibody MCLA-158' SubClassOf 'Bispecific Antibody'</newAxiom>
<newAxiom>'Anti-EGFR/LGR5 Bispecific Antibody MCLA-158' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179195</classIRI>
<classLabel>Concentrate and Solvent for Dispersion for Injection</classLabel>
<newAxiom>'Concentrate and Solvent for Dispersion for Injection' SubClassOf 'Combined Dosage Form'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179179</classIRI>
<classLabel>Recurrent Pseudomyxoma Peritonei</classLabel>
<newAxiom>'Recurrent Pseudomyxoma Peritonei' EquivalentTo 'Recurrent Metastatic Malignant Neoplasm' and 'Recurrent Adenocarcinoma' and 'Pseudomyxoma Peritonei'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179181</classIRI>
<classLabel>Locally Advanced Malignant Digestive System Neoplasm</classLabel>
<newAxiom>'Locally Advanced Malignant Digestive System Neoplasm' EquivalentTo 'Metastatic Malignant Digestive System Neoplasm' and 'Locally Advanced Malignant Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179180</classIRI>
<classLabel>Refractory Pseudomyxoma Peritonei</classLabel>
<newAxiom>'Refractory Pseudomyxoma Peritonei' EquivalentTo 'Refractory Adenocarcinoma' and 'Pseudomyxoma Peritonei'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179187</classIRI>
<classLabel>Autologous Cytokine-induced Killer Cells/Vaccinia Virus DD-CDSR CRX100</classLabel>
<newAxiom>'Autologous Cytokine-induced Killer Cells/Vaccinia Virus DD-CDSR CRX100' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous Cytokine-induced Killer Cells/Vaccinia Virus DD-CDSR CRX100' SubClassOf 'Vaccinia Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179186</classIRI>
<classLabel>Doxycycline Hyclate Matrix Formulation</classLabel>
<newAxiom>'Doxycycline Hyclate Matrix Formulation' SubClassOf 'Tetracycline Antibiotic'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179189</classIRI>
<classLabel>Systolic Hypotension</classLabel>
<newAxiom>'Systolic Hypotension' SubClassOf 'Hypotension'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179188</classIRI>
<classLabel>Leaky Severe Combined Immunodeficiency</classLabel>
<newAxiom>'Leaky Severe Combined Immunodeficiency' SubClassOf 'Severe Combined Immunodeficiency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179183</classIRI>
<classLabel>Action Research Arm Test</classLabel>
<newAxiom>'Action Research Arm Test' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179182</classIRI>
<classLabel>Locally Recurrent Uterine Corpus Leiomyosarcoma</classLabel>
<newAxiom>'Locally Recurrent Uterine Corpus Leiomyosarcoma' EquivalentTo 'Uterine Corpus Leiomyosarcoma' and 'Recurrent Uterine Corpus Sarcoma' and 'Recurrent Leiomyosarcoma' and 'Locally Recurrent Malignant Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179185</classIRI>
<classLabel>Proprioception Assessment</classLabel>
<newAxiom>'Proprioception Assessment' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179184</classIRI>
<classLabel>Motor Function Assessment</classLabel>
<newAxiom>'Motor Function Assessment' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179169</classIRI>
<classLabel>Near Infrared Spectroscopy</classLabel>
<newAxiom>'Near Infrared Spectroscopy' SubClassOf 'Spectroscopy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179168</classIRI>
<classLabel>Anti-CSF1R Monoclonal Antibody AMB-05X</classLabel>
<newAxiom>'Anti-CSF1R Monoclonal Antibody AMB-05X' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-CSF1R Monoclonal Antibody AMB-05X' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179170</classIRI>
<classLabel>International Pediatric Non-Hodgkin Lymphoma Response Criteria</classLabel>
<newAxiom>'International Pediatric Non-Hodgkin Lymphoma Response Criteria' SubClassOf 'Classification'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179176</classIRI>
<classLabel>Unsolicited Adverse Event</classLabel>
<newAxiom>'Unsolicited Adverse Event' SubClassOf 'Adverse Event'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179175</classIRI>
<classLabel>Solicited Adverse Event</classLabel>
<newAxiom>'Solicited Adverse Event' SubClassOf 'Adverse Event'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179178</classIRI>
<classLabel>Refractory Appendix Adenocarcinoma</classLabel>
<newAxiom>'Refractory Appendix Adenocarcinoma' EquivalentTo 'Refractory Adenocarcinoma' and 'Refractory Appendix Carcinoma' and 'Appendix Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179177</classIRI>
<classLabel>Refractory Appendix Carcinoma</classLabel>
<newAxiom>'Refractory Appendix Carcinoma' EquivalentTo 'Refractory Digestive System Carcinoma' and 'Appendix Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179172</classIRI>
<classLabel>Behavioral Activation Therapy</classLabel>
<newAxiom>'Behavioral Activation Therapy' SubClassOf 'Cognitive Behavior Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179171</classIRI>
<classLabel>mTORC1 Kinase Inhibitor RMC-5552</classLabel>
<newAxiom>'mTORC1 Kinase Inhibitor RMC-5552' SubClassOf 'mTOR Inhibitor'</newAxiom>
<newAxiom>'mTORC1 Kinase Inhibitor RMC-5552' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179174</classIRI>
<classLabel>Recurrent Appendix Adenocarcinoma</classLabel>
<newAxiom>'Recurrent Appendix Adenocarcinoma' EquivalentTo 'Recurrent Appendix Carcinoma' and 'Recurrent Adenocarcinoma' and 'Appendix Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179173</classIRI>
<classLabel>Solicit</classLabel>
<newAxiom>'Solicit' SubClassOf 'Action'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179158</classIRI>
<classLabel>PDK2 Gene</classLabel>
<newAxiom>'PDK2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Fatty Acid Metabolism'</newAxiom>
<newAxiom>'PDK2 Gene' SubClassOf 'Serine/Threonine Protein Kinase Gene'</newAxiom>
<newAxiom>'PDK2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Carbohydrate Metabolic Process'</newAxiom>
<newAxiom>'PDK2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Serine/Threonine Phosphorylation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179157</classIRI>
<classLabel>Corticotropin-Releasing Factor Receptor 2</classLabel>
<newAxiom>'Corticotropin-Releasing Factor Receptor 2' EquivalentTo 'G Protein-Coupled Receptor' and ('Gene_Product_Is_Element_In_Pathway' some 'Neuroactive Ligand-Receptor Signaling Pathway') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Ligand Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'G Protein-Coupled Receptor Signaling') and ('Gene_Product_Encoded_By_Gene' some 'CRHR2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179159</classIRI>
<classLabel>PDK2 wt Allele</classLabel>
<newAxiom>'PDK2 wt Allele' SubClassOf 'PDK2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179165</classIRI>
<classLabel>Arterial-phase Contrast Enhancement Magnetic Resonance Imaging</classLabel>
<newAxiom>'Arterial-phase Contrast Enhancement Magnetic Resonance Imaging' SubClassOf 'Magnetic Resonance Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179164</classIRI>
<classLabel>Multiphasic Magnetic Resonance Imaging</classLabel>
<newAxiom>'Multiphasic Magnetic Resonance Imaging' SubClassOf 'Magnetic Resonance Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179167</classIRI>
<classLabel>Human Embryonic Stem Cell-derived Midbrain Dopamine Neuron Cells MSK-DA01</classLabel>
<newAxiom>'Human Embryonic Stem Cell-derived Midbrain Dopamine Neuron Cells MSK-DA01' SubClassOf 'Adoptive Cell Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179166</classIRI>
<classLabel>Venous-phase Contrast Enhancement Magnetic Resonance Imaging</classLabel>
<newAxiom>'Venous-phase Contrast Enhancement Magnetic Resonance Imaging' SubClassOf 'Magnetic Resonance Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179161</classIRI>
<classLabel>PDK3 Gene</classLabel>
<newAxiom>'PDK3 Gene' SubClassOf 'Serine/Threonine Protein Kinase Gene'</newAxiom>
<newAxiom>'PDK3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Carbohydrate Metabolic Process'</newAxiom>
<newAxiom>'PDK3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Serine/Threonine Phosphorylation'</newAxiom>
<newAxiom>'PDK3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell Respiration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179160</classIRI>
<classLabel>[Pyruvate Dehydrogenase (Acetyl-Transferring)] Kinase Isozyme 2, Mitochondrial</classLabel>
<newAxiom>'[Pyruvate Dehydrogenase (Acetyl-Transferring)] Kinase Isozyme 2, Mitochondrial' EquivalentTo 'Serine/Threonine Protein Kinase' and ('Gene_Product_Has_Associated_Anatomy' some 'Mitochondrial Matrix') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Carbohydrate Metabolic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Serine/Threonine Phosphorylation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Fatty Acid Metabolism') and ('Gene_Product_Encoded_By_Gene' some 'PDK2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179163</classIRI>
<classLabel>[Pyruvate Dehydrogenase (Acetyl-Transferring)] Kinase Isozyme 3, Mitochondrial</classLabel>
<newAxiom>'[Pyruvate Dehydrogenase (Acetyl-Transferring)] Kinase Isozyme 3, Mitochondrial' EquivalentTo 'Serine/Threonine Protein Kinase' and ('Gene_Product_Has_Associated_Anatomy' some 'Mitochondrial Matrix') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Respiration') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Carbohydrate Metabolic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Serine/Threonine Phosphorylation') and ('Gene_Product_Encoded_By_Gene' some 'PDK3 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179162</classIRI>
<classLabel>PDK3 wt Allele</classLabel>
<newAxiom>'PDK3 wt Allele' SubClassOf 'PDK3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179147</classIRI>
<classLabel>TICAM1 Gene</classLabel>
<newAxiom>'TICAM1 Gene' SubClassOf 'Adaptor Signaling Protein Gene'</newAxiom>
<newAxiom>'TICAM1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Antibacterial Response'</newAxiom>
<newAxiom>'TICAM1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Antiviral Response'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179146</classIRI>
<classLabel>Transmembrane Emp24 Domain-Containing Protein 2</classLabel>
<newAxiom>'Transmembrane Emp24 Domain-Containing Protein 2' EquivalentTo 'Transport Protein' and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Coated Vesicle') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Golgi Apparatus') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Rough Endoplasmic Reticulum') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Smooth Endoplasmic Reticulum') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Coiled-Coil Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Secretion') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Subcellular Protein Targeting') and ('Gene_Product_Encoded_By_Gene' some 'TMED2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179149</classIRI>
<classLabel>TIR Domain-Containing Adapter Molecule 1</classLabel>
<newAxiom>'TIR Domain-Containing Adapter Molecule 1' EquivalentTo 'Adaptor Signaling Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Toll-Like Receptor Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'NOD-Like Receptor Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Chagas Disease Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoplasm') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Proline-Rich Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Antiviral Response') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Antibacterial Response') and ('Gene_Product_Encoded_By_Gene' some 'TICAM1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179148</classIRI>
<classLabel>TICAM1 wt Allele</classLabel>
<newAxiom>'TICAM1 wt Allele' EquivalentTo 'TICAM1 Gene' and ('Gene_Is_Element_In_Pathway' some 'Toll-Like Receptor Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'NOD-Like Receptor Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Chagas Disease Pathway') and ('Gene_In_Chromosomal_Location' some '19p13.3')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179154</classIRI>
<classLabel>Protein Unc-93 Homolog B1</classLabel>
<newAxiom>'Protein Unc-93 Homolog B1' EquivalentTo 'Transport Protein' and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Antigen Presenting Cell') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Endosome') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Golgi Apparatus') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Rough Endoplasmic Reticulum') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Smooth Endoplasmic Reticulum') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immunity') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Receptor Signaling') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Subcellular Protein Targeting') and ('Gene_Product_Encoded_By_Gene' some 'UNC93B1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179153</classIRI>
<classLabel>UNC93B1 wt Allele</classLabel>
<newAxiom>'UNC93B1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '11q13.2'</newAxiom>
<newAxiom>'UNC93B1 wt Allele' SubClassOf 'UNC93B1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179156</classIRI>
<classLabel>CRHR2 wt Allele</classLabel>
<newAxiom>'CRHR2 wt Allele' SubClassOf 'CRHR2 Gene'</newAxiom>
<newAxiom>'CRHR2 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Neuroactive Ligand-Receptor Signaling Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179155</classIRI>
<classLabel>CRHR2 Gene</classLabel>
<newAxiom>'CRHR2 Gene' SubClassOf 'G Protein-Coupled Receptor Gene'</newAxiom>
<newAxiom>'CRHR2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Ligand Binding'</newAxiom>
<newAxiom>'CRHR2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'G Protein-Coupled Receptor Signaling'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179150</classIRI>
<classLabel>Perilesional Route of Administration</classLabel>
<newAxiom>'Perilesional Route of Administration' SubClassOf 'Parenteral Route of Administration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179152</classIRI>
<classLabel>UNC93B1 Gene</classLabel>
<newAxiom>'UNC93B1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Receptor Binding'</newAxiom>
<newAxiom>'UNC93B1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Receptor Signaling'</newAxiom>
<newAxiom>'UNC93B1 Gene' SubClassOf 'Trafficking Protein Gene'</newAxiom>
<newAxiom>'UNC93B1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immunity'</newAxiom>
<newAxiom>'UNC93B1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Subcellular Protein Targeting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179151</classIRI>
<classLabel>Platinum-Resistant Head and Neck Carcinoma</classLabel>
<newAxiom>'Platinum-Resistant Head and Neck Carcinoma' EquivalentTo 'Refractory Head and Neck Carcinoma' and ('Disease_Has_Finding' some 'Platinum-Resistant Disease')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179139</classIRI>
<classLabel>FAS-Associated Factor 2</classLabel>
<newAxiom>'FAS-Associated Factor 2' EquivalentTo 'Regulatory Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Endoplasmic Reticulum') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Coiled-Coil Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'UBA Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Unfolded Protein Response') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Turnover') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Ubiquitinated Protein Degradation') and ('Gene_Product_Encoded_By_Gene' some 'FAF2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179136</classIRI>
<classLabel>Zilebesiran</classLabel>
<newAxiom>'Zilebesiran' SubClassOf 'Antihypertensive Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179135</classIRI>
<classLabel>Zaloglanstat</classLabel>
<newAxiom>'Zaloglanstat' SubClassOf 'Cyclooxygenase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179138</classIRI>
<classLabel>FAF2 wt Allele</classLabel>
<newAxiom>'FAF2 wt Allele' SubClassOf 'FAF2 Gene'</newAxiom>
<newAxiom>'FAF2 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '5q35.2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179137</classIRI>
<classLabel>FAF2 Gene</classLabel>
<newAxiom>'FAF2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Unfolded Protein Response'</newAxiom>
<newAxiom>'FAF2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Turnover'</newAxiom>
<newAxiom>'FAF2 Gene' SubClassOf 'Regulatory Gene'</newAxiom>
<newAxiom>'FAF2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Ubiquitinated Protein Degradation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179143</classIRI>
<classLabel>Employment Status</classLabel>
<newAxiom>'Employment Status' SubClassOf 'Personal Attribute'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179142</classIRI>
<classLabel>Sorting Nexin-8</classLabel>
<newAxiom>'Sorting Nexin-8' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Lipid Binding'</newAxiom>
<newAxiom>'Sorting Nexin-8' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Intracellular Membrane'</newAxiom>
<newAxiom>'Sorting Nexin-8' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'SNX8 Gene'</newAxiom>
<newAxiom>'Sorting Nexin-8' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Subcellular Protein Targeting'</newAxiom>
<newAxiom>'Sorting Nexin-8' SubClassOf 'Transport Protein'</newAxiom>
<newAxiom>'Sorting Nexin-8' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Endosome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179145</classIRI>
<classLabel>TMED2 wt Allele</classLabel>
<newAxiom>'TMED2 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '12q24.31'</newAxiom>
<newAxiom>'TMED2 wt Allele' SubClassOf 'TMED2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179144</classIRI>
<classLabel>TMED2 Gene</classLabel>
<newAxiom>'TMED2 Gene' SubClassOf 'Trafficking Protein Gene'</newAxiom>
<newAxiom>'TMED2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Secretion'</newAxiom>
<newAxiom>'TMED2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Subcellular Protein Targeting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179141</classIRI>
<classLabel>SNX8 wt Allele</classLabel>
<newAxiom>'SNX8 wt Allele' SubClassOf 'SNX8 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179140</classIRI>
<classLabel>SNX8 Gene</classLabel>
<newAxiom>'SNX8 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Subcellular Protein Targeting'</newAxiom>
<newAxiom>'SNX8 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Lipid Binding'</newAxiom>
<newAxiom>'SNX8 Gene' SubClassOf 'Trafficking Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179008</classIRI>
<classLabel>Vital Stain</classLabel>
<newAxiom>'Vital Stain' SubClassOf 'Dye'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179007</classIRI>
<classLabel>Viable Cells by Hemocytometry</classLabel>
<newAxiom>'Viable Cells by Hemocytometry' SubClassOf 'Viable Cell Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179009</classIRI>
<classLabel>Approved for Emergency Use Authorization</classLabel>
<newAxiom>'Approved for Emergency Use Authorization' SubClassOf 'Emergency Use Authorization Status'</newAxiom>
</newClass>
<newClass>
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<classLabel>Viability by Automated Count</classLabel>
<newAxiom>'Viability by Automated Count' SubClassOf 'Sample Viability Percent Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179003</classIRI>
<classLabel>Total Cells by Hemocytometry</classLabel>
<newAxiom>'Total Cells by Hemocytometry' SubClassOf 'Cell Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179006</classIRI>
<classLabel>Viable Cells by Automated Count</classLabel>
<newAxiom>'Viable Cells by Automated Count' SubClassOf 'Viable Cell Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179005</classIRI>
<classLabel>Viability by Hemocytometry</classLabel>
<newAxiom>'Viability by Hemocytometry' SubClassOf 'Sample Viability Percent Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179011</classIRI>
<classLabel>COVID-19 Disease Severity 1</classLabel>
<newAxiom>'COVID-19 Disease Severity 1' SubClassOf 'COVID-19 Disease Severity Scale'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179010</classIRI>
<classLabel>COVID-19 Disease Severity 0</classLabel>
<newAxiom>'COVID-19 Disease Severity 0' SubClassOf 'COVID-19 Disease Severity Scale'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179013</classIRI>
<classLabel>COVID-19 Disease Severity 3</classLabel>
<newAxiom>'COVID-19 Disease Severity 3' SubClassOf 'COVID-19 Disease Severity Scale'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179012</classIRI>
<classLabel>COVID-19 Disease Severity 2</classLabel>
<newAxiom>'COVID-19 Disease Severity 2' SubClassOf 'COVID-19 Disease Severity Scale'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179000</classIRI>
<classLabel>Target Organism</classLabel>
<newAxiom>'Target Organism' SubClassOf 'Organism'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179002</classIRI>
<classLabel>Total Cells by Automated Count</classLabel>
<newAxiom>'Total Cells by Automated Count' SubClassOf 'Cell Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179001</classIRI>
<classLabel>Test Operator Initials</classLabel>
<newAxiom>'Test Operator Initials' SubClassOf 'Person Initials'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179129</classIRI>
<classLabel>Tozorakimab</classLabel>
<newAxiom>'Tozorakimab' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179128</classIRI>
<classLabel>Torudokimab</classLabel>
<newAxiom>'Torudokimab' SubClassOf 'Immunotherapeutic Agent'</newAxiom>
<newAxiom>'Torudokimab' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179125</classIRI>
<classLabel>Temgicoluril</classLabel>
<newAxiom>'Temgicoluril' SubClassOf 'Agent Affecting Nervous System'</newAxiom>
</newClass>
<newClass>
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<classLabel>Tadnersen</classLabel>
<newAxiom>'Tadnersen' SubClassOf 'Antisense RNA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179127</classIRI>
<classLabel>Tomligisiran</classLabel>
<newAxiom>'Tomligisiran' SubClassOf 'Antiviral Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179126</classIRI>
<classLabel>Tigulixostat</classLabel>
<newAxiom>'Tigulixostat' SubClassOf 'Xanthine Oxidase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179132</classIRI>
<classLabel>Usmarapride</classLabel>
<newAxiom>'Usmarapride' SubClassOf 'Serotonin Agonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179131</classIRI>
<classLabel>Unasnemab</classLabel>
<newAxiom>'Unasnemab' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179134</classIRI>
<classLabel>Zabedosertib</classLabel>
<newAxiom>'Zabedosertib' SubClassOf 'Serine/Threonine Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179133</classIRI>
<classLabel>Varoglutamstat</classLabel>
<newAxiom>'Varoglutamstat' SubClassOf 'Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179130</classIRI>
<classLabel>Ulotaront</classLabel>
<newAxiom>'Ulotaront' SubClassOf 'Antipsychotic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179118</classIRI>
<classLabel>Sapablursen</classLabel>
<newAxiom>'Sapablursen' SubClassOf 'Antisense Oligonucleotides'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179117</classIRI>
<classLabel>Ropanicant</classLabel>
<newAxiom>'Ropanicant' SubClassOf 'Nicotinic Antagonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179119</classIRI>
<classLabel>Sesiclenegene Cosaparvovec</classLabel>
<newAxiom>'Sesiclenegene Cosaparvovec' SubClassOf 'Gene Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179114</classIRI>
<classLabel>Pemziviptadil</classLabel>
<newAxiom>'Pemziviptadil' SubClassOf 'Therapeutic Hormone'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179113</classIRI>
<classLabel>Peboctocogene Camaparvovec</classLabel>
<newAxiom>'Peboctocogene Camaparvovec' SubClassOf 'Gene Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179116</classIRI>
<classLabel>Prusogliptin</classLabel>
<newAxiom>'Prusogliptin' SubClassOf 'Dipeptidyl Peptidase-4 Inhibitor'</newAxiom>
</newClass>
<newClass>
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<classLabel>Plazinemdor</classLabel>
<newAxiom>'Plazinemdor' SubClassOf 'Antipsychotic Agent'</newAxiom>
</newClass>
<newClass>
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<classLabel>Simpinicline</classLabel>
<newAxiom>'Simpinicline' SubClassOf 'Nicotinic Agonist'</newAxiom>
</newClass>
<newClass>
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<classLabel>Sibeprenlimab</classLabel>
<newAxiom>'Sibeprenlimab' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
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<classLabel>Sunobinop</classLabel>
<newAxiom>'Sunobinop' SubClassOf 'Opioid Receptor Agonist'</newAxiom>
</newClass>
<newClass>
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<classLabel>Sirelretigene Suboparvove</classLabel>
<newAxiom>'Sirelretigene Suboparvove' SubClassOf 'Gene Therapy Agent'</newAxiom>
</newClass>
<newClass>
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<classLabel>Nezulcitinib</classLabel>
<newAxiom>'Nezulcitinib' SubClassOf 'JAK Inhibitor'</newAxiom>
</newClass>
<newClass>
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<classLabel>Nendratareotide</classLabel>
<newAxiom>'Nendratareotide' SubClassOf 'Recombinant Somatostatin'</newAxiom>
</newClass>
<newClass>
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<classLabel>Ninerafaxstat</classLabel>
<newAxiom>'Ninerafaxstat' SubClassOf 'Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
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<classLabel>Nilofabicin</classLabel>
<newAxiom>'Nilofabicin' SubClassOf 'Antibiotic'</newAxiom>
</newClass>
<newClass>
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<classLabel>Mibavademab</classLabel>
<newAxiom>'Mibavademab' SubClassOf 'Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179102</classIRI>
<classLabel>Lusvertikimab</classLabel>
<newAxiom>'Lusvertikimab' SubClassOf 'Monoclonal Antibody'</newAxiom>
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<newClass>
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<classLabel>Nanvuranlat</classLabel>
<newAxiom>'Nanvuranlat' SubClassOf 'Antineoplastic Protein Inhibitor'</newAxiom>
</newClass>
<newClass>
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<classLabel>Nadecnemab</classLabel>
<newAxiom>'Nadecnemab' SubClassOf 'Monoclonal Antibody'</newAxiom>
<newAxiom>'Nadecnemab' SubClassOf 'Analgesic Agent'</newAxiom>
</newClass>
<newClass>
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<classLabel>Palopegteriparatide</classLabel>
<newAxiom>'Palopegteriparatide' SubClassOf 'Recombinant Parathyroid Hormone'</newAxiom>
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<newClass>
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<classLabel>Oremepermin Alfa</classLabel>
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<classLabel>Lonigutamab Ugodotin</classLabel>
<newAxiom>'Lonigutamab Ugodotin' SubClassOf 'Monoclonal Antibody'</newAxiom>
<newAxiom>'Lonigutamab Ugodotin' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
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<classLabel>Licaminlimab</classLabel>
<newAxiom>'Licaminlimab' SubClassOf 'Monoclonal Antibody'</newAxiom>
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<classLabel>Inupadenant Hydrochloride</classLabel>
<newAxiom>'Inupadenant Hydrochloride' SubClassOf 'Immunostimulant'</newAxiom>
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<newClass>
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<classLabel>Ilofotase Alfa</classLabel>
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<newClass>
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<classLabel>Irsenontrine Maleate</classLabel>
<newAxiom>'Irsenontrine Maleate' SubClassOf 'Phosphodiesterase Inhibitor'</newAxiom>
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<newClass>
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<classLabel>Irsenontrine</classLabel>
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<classLabel>Libvatrep</classLabel>
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<classLabel>Latozinemab</classLabel>
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<newAxiom>'Latozinemab' SubClassOf 'Dopamine Agonist'</newAxiom>
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<classLabel>Isuzinaxib</classLabel>
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<classLabel>Isaralgagene Civaparvovec</classLabel>
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<newClass>
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<classLabel>Larsucosterol</classLabel>
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<classLabel>Labuvirtide</classLabel>
<newAxiom>'Labuvirtide' SubClassOf 'Anti-HIV Agent'</newAxiom>
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<classLabel>Defosbarasertib</classLabel>
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<newAxiom>'Defosbarasertib' SubClassOf 'Aurora Kinase Inhibitor'</newAxiom>
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<classLabel>Ebdarokimab</classLabel>
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<classLabel>Ebaresdax</classLabel>
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<classLabel>Govorestat</classLabel>
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<classLabel>Firzacorvir</classLabel>
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<classLabel>Encoberminogene Rezmadenovec</classLabel>
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<classLabel>Adezmapimod</classLabel>
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<newClass>
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<classLabel>Cofirasersen Sodium</classLabel>
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<classLabel>Amlitelimab</classLabel>
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<classLabel>Aficamten</classLabel>
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</newClass>
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<classLabel>Bevufenogene Nofeparvovec</classLabel>
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</newClass>
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<classLabel>Atuzaginstat</classLabel>
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<classLabel>SeroNet Schema Details</classLabel>
<newAxiom>'SeroNet Schema Details' SubClassOf 'SeroNet Terminology'</newAxiom>
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<classLabel>HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis</classLabel>
<newAxiom>'HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis' SubClassOf 'Central Nervous System Infectious Disorder'</newAxiom>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179060</classIRI>
<classLabel>SeroNet Schema Version</classLabel>
<newAxiom>'SeroNet Schema Version' SubClassOf 'Identifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179066</classIRI>
<classLabel>Genetic Predisposition to Disease</classLabel>
<newAxiom>'Genetic Predisposition to Disease' SubClassOf 'Finding by Cause'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179065</classIRI>
<classLabel>Ensovibep</classLabel>
<newAxiom>'Ensovibep' SubClassOf 'Immunotherapeutic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179068</classIRI>
<classLabel>Acavameran</classLabel>
<newAxiom>'Acavameran' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179067</classIRI>
<classLabel>Susceptibility to Idiopathic Generalized Epilepsy-15</classLabel>
<newAxiom>'Susceptibility to Idiopathic Generalized Epilepsy-15' SubClassOf 'Genetic Predisposition to Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179062</classIRI>
<classLabel>Multiphasic Contrast-enhanced MRI</classLabel>
<newAxiom>'Multiphasic Contrast-enhanced MRI' SubClassOf 'Contrast-enhanced Magnetic Resonance Imaging'</newAxiom>
<newAxiom>'Multiphasic Contrast-enhanced MRI' SubClassOf 'Multiphasic Magnetic Resonance Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179061</classIRI>
<classLabel>Diffusion Weighted MRI with Background Subtraction</classLabel>
<newAxiom>'Diffusion Weighted MRI with Background Subtraction' SubClassOf 'Diffusion Weighted Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179064</classIRI>
<classLabel>Delayed-phase Contrast Enhancement Magnetic Resonance Imaging</classLabel>
<newAxiom>'Delayed-phase Contrast Enhancement Magnetic Resonance Imaging' SubClassOf 'Contrast-enhanced Magnetic Resonance Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179063</classIRI>
<classLabel>Multiphasic Unenhanced MRI</classLabel>
<newAxiom>'Multiphasic Unenhanced MRI' SubClassOf 'MRI Without Contrast'</newAxiom>
<newAxiom>'Multiphasic Unenhanced MRI' SubClassOf 'Multiphasic Magnetic Resonance Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179048</classIRI>
<classLabel>Have Decreased Desire for Anal Sexual Activity</classLabel>
<newAxiom>'Have Decreased Desire for Anal Sexual Activity' SubClassOf 'Sex Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179047</classIRI>
<classLabel>Have Decreased Enjoyment of Sexual Activity Other than Anal Activity</classLabel>
<newAxiom>'Have Decreased Enjoyment of Sexual Activity Other than Anal Activity' SubClassOf 'Sex Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179049</classIRI>
<classLabel>Have Decreased Desire for Sexual Activity Other than Anal Sexual Activity</classLabel>
<newAxiom>'Have Decreased Desire for Sexual Activity Other than Anal Sexual Activity' SubClassOf 'Sex Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179055</classIRI>
<classLabel>Rat Lymphosarcoma</classLabel>
<newAxiom>'Rat Lymphosarcoma' SubClassOf 'Rat Neoplasms by Morphology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179054</classIRI>
<classLabel>Familial Hypertrophic Cardiomyopathy Type 27</classLabel>
<newAxiom>'Familial Hypertrophic Cardiomyopathy Type 27' SubClassOf 'Familial Hypertrophic Cardiomyopathy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179057</classIRI>
<classLabel>Primary Hypertrophic Osteoarthropathy, Autosomal Recessive Type 1</classLabel>
<newAxiom>'Primary Hypertrophic Osteoarthropathy, Autosomal Recessive Type 1' SubClassOf 'Primary Hypertrophic Osteoarthropathy'</newAxiom>
<newAxiom>'Primary Hypertrophic Osteoarthropathy, Autosomal Recessive Type 1' SubClassOf 'Disease_Mapped_To_Gene' some 'HPGD Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179056</classIRI>
<classLabel>Rat Thyroid Neoplasm</classLabel>
<newAxiom>'Rat Thyroid Neoplasm' SubClassOf 'Rat Neoplasms by Morphology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179051</classIRI>
<classLabel>Have Problems with Intimate Relationships</classLabel>
<newAxiom>'Have Problems with Intimate Relationships' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179050</classIRI>
<classLabel>Worry about My Condition Worsening</classLabel>
<newAxiom>'Worry about My Condition Worsening' SubClassOf 'Worry Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179053</classIRI>
<classLabel>T/NK-Cell Lymphoproliferative Disorder</classLabel>
<newAxiom>'T/NK-Cell Lymphoproliferative Disorder' EquivalentTo 'Lymphoproliferative Disorder' and ('Disease_Has_Normal_Cell_Origin' some 'T-Lymphocyte and Natural Killer Cell')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179052</classIRI>
<classLabel>B-Cell Lymphoproliferative Disorder</classLabel>
<newAxiom>'B-Cell Lymphoproliferative Disorder' EquivalentTo 'Lymphoproliferative Disorder' and ('Disease_Has_Normal_Cell_Origin' some 'B-Lymphocyte')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179037</classIRI>
<classLabel>Have Burning Sensations in Anal Area</classLabel>
<newAxiom>'Have Burning Sensations in Anal Area' SubClassOf 'Have Symptom or Condition Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179036</classIRI>
<classLabel>Have Discharge or Wetness in Anal Area</classLabel>
<newAxiom>'Have Discharge or Wetness in Anal Area' SubClassOf 'Have Symptom or Condition Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179039</classIRI>
<classLabel>Have Problems with Physical Ability to Move Around</classLabel>
<newAxiom>'Have Problems with Physical Ability to Move Around' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179038</classIRI>
<classLabel>Have Urgency for Bowel Movements</classLabel>
<newAxiom>'Have Urgency for Bowel Movements' SubClassOf 'Have Symptom or Condition Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179044</classIRI>
<classLabel>Have Problems Participating in Social Activities</classLabel>
<newAxiom>'Have Problems Participating in Social Activities' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
<newAxiom>'Have Problems Participating in Social Activities' SubClassOf 'Activity Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179043</classIRI>
<classLabel>Have Problems Participating in Leisure Activities</classLabel>
<newAxiom>'Have Problems Participating in Leisure Activities' SubClassOf 'Activity Question'</newAxiom>
<newAxiom>'Have Problems Participating in Leisure Activities' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179046</classIRI>
<classLabel>Have Decreased Enjoyment of Anal Sexual Activity</classLabel>
<newAxiom>'Have Decreased Enjoyment of Anal Sexual Activity' SubClassOf 'Sex Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179045</classIRI>
<classLabel>Have Problems with Work Productivity</classLabel>
<newAxiom>'Have Problems with Work Productivity' SubClassOf 'Work Question'</newAxiom>
<newAxiom>'Have Problems with Work Productivity' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179040</classIRI>
<classLabel>Have Problems with Sitting</classLabel>
<newAxiom>'Have Problems with Sitting' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179042</classIRI>
<classLabel>Have Problems Taking Care of Myself</classLabel>
<newAxiom>'Have Problems Taking Care of Myself' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179041</classIRI>
<classLabel>Have Problems Completing Daily Household Chores</classLabel>
<newAxiom>'Have Problems Completing Daily Household Chores' SubClassOf 'Have Trouble or Difficulty Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179029</classIRI>
<classLabel>Have Anal Pain</classLabel>
<newAxiom>'Have Anal Pain' SubClassOf 'Pain Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179026</classIRI>
<classLabel>SeroNet Variables</classLabel>
<newAxiom>'SeroNet Variables' SubClassOf 'SeroNet Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179025</classIRI>
<classLabel>Submitted for Emergency Use Authorization</classLabel>
<newAxiom>'Submitted for Emergency Use Authorization' SubClassOf 'Emergency Use Authorization Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179028</classIRI>
<classLabel>ANCHOR Health-Related Symptom Index</classLabel>
<newAxiom>'ANCHOR Health-Related Symptom Index' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179027</classIRI>
<classLabel>SeroNet Permissible Values</classLabel>
<newAxiom>'SeroNet Permissible Values' SubClassOf 'SeroNet Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179033</classIRI>
<classLabel>Have Bleeding from Anus</classLabel>
<newAxiom>'Have Bleeding from Anus' SubClassOf 'Bleeding Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179032</classIRI>
<classLabel>Bleeding Question</classLabel>
<newAxiom>'Bleeding Question' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179035</classIRI>
<classLabel>Have Itching in or Around Anus</classLabel>
<newAxiom>'Have Itching in or Around Anus' SubClassOf 'Have Itch'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179031</classIRI>
<classLabel>Have Pain During Bowel Movements</classLabel>
<newAxiom>'Have Pain During Bowel Movements' SubClassOf 'Pain Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179030</classIRI>
<classLabel>Have Pain Other than Anal Pain</classLabel>
<newAxiom>'Have Pain Other than Anal Pain' SubClassOf 'Pain Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179019</classIRI>
<classLabel>Multiplex Assay</classLabel>
<newAxiom>'Multiplex Assay' SubClassOf 'Assay Multiplicity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179018</classIRI>
<classLabel>COVID-19 Disease Severity 8</classLabel>
<newAxiom>'COVID-19 Disease Severity 8' SubClassOf 'COVID-19 Disease Severity Scale'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179015</classIRI>
<classLabel>COVID-19 Disease Severity 5</classLabel>
<newAxiom>'COVID-19 Disease Severity 5' SubClassOf 'COVID-19 Disease Severity Scale'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179014</classIRI>
<classLabel>COVID-19 Disease Severity 4</classLabel>
<newAxiom>'COVID-19 Disease Severity 4' SubClassOf 'COVID-19 Disease Severity Scale'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179017</classIRI>
<classLabel>COVID-19 Disease Severity 7</classLabel>
<newAxiom>'COVID-19 Disease Severity 7' SubClassOf 'COVID-19 Disease Severity Scale'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179016</classIRI>
<classLabel>COVID-19 Disease Severity 6</classLabel>
<newAxiom>'COVID-19 Disease Severity 6' SubClassOf 'COVID-19 Disease Severity Scale'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179022</classIRI>
<classLabel>Positive Biospecimen</classLabel>
<newAxiom>'Positive Biospecimen' SubClassOf 'Biospecimen Group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179021</classIRI>
<classLabel>Not Submitted for Emergency Use Authorization</classLabel>
<newAxiom>'Not Submitted for Emergency Use Authorization' SubClassOf 'Emergency Use Authorization Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179024</classIRI>
<classLabel>Singleplex Assay</classLabel>
<newAxiom>'Singleplex Assay' SubClassOf 'Assay Multiplicity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179023</classIRI>
<classLabel>Serosurveillance Biospecimen</classLabel>
<newAxiom>'Serosurveillance Biospecimen' SubClassOf 'Biospecimen Group'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179020</classIRI>
<classLabel>Negative Biospecimen</classLabel>
<newAxiom>'Negative Biospecimen' SubClassOf 'Biospecimen Group'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>