<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
552
</numberChangedClasses>
<numberNewClasses>
637
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C53147</classIRI>
<classLabel>Biceps Femoris</classLabel>
<deletedAxiom>&apos;Biceps Femoris&apos; SubClassOf &apos;Biceps&apos;</deletedAxiom>
<newAxiom>&apos;Biceps Femoris&apos; SubClassOf &apos;Muscle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C105048</classIRI>
<classLabel>Unhappy with Face and Neck Appearance</classLabel>
<newAxiom>&apos;Unhappy with Face and Neck Appearance&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3339</classIRI>
<classLabel>Familial Adenomatous Polyposis</classLabel>
<deletedAxiom>&apos;Familial Adenomatous Polyposis&apos; EquivalentTo &apos;Hereditary Colorectal Cancer Syndrome&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;APC Gene Inactivation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Diarrhea&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Colorectal Carcinoma&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Adenomatous Polyp&apos;) and (&apos;Disease_Mapped_To_Chromosome&apos; some &apos;Chromosome 5&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;APC Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Familial Adenomatous Polyposis&apos; EquivalentTo &apos;Hereditary Colorectal Cancer Syndrome&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;APC Gene Inactivation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Diarrhea&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Colorectal Carcinoma&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Adenomatous Polyp&apos;) and (&apos;Disease_Mapped_To_Chromosome&apos; some &apos;Chromosome 5&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;APC Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3273</classIRI>
<classLabel>Neurofibromatosis Type 1</classLabel>
<deletedAxiom>&apos;Neurofibromatosis Type 1&apos; EquivalentTo &apos;Neurofibromatosis&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;NF1 Gene Inactivation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Cafe Au Lait Spot&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;NF1-Associated Malignant Peripheral Nerve Sheath Tumor&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Seizure Disorder&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Hydrocephalus&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Adrenal Gland Pheochromocytoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Rhabdomyosarcoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Macrocephaly&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Pilocytic Astrocytoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Optic Nerve Glioma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Neuropathy&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Duodenal Neuroendocrine Tumor G1&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ampulla of Vater Neuroendocrine Neoplasm&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Neurofibroma&apos;) and (&apos;Disease_Mapped_To_Chromosome&apos; some &apos;Chromosome 17&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;NF1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Neurofibromatosis Type 1&apos; EquivalentTo &apos;Neurofibromatosis&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;NF1 Gene Inactivation&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Cafe Au Lait Spot&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;NF1-Associated Malignant Peripheral Nerve Sheath Tumor&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Seizure Disorder&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Hydrocephalus&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Adrenal Gland Pheochromocytoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Rhabdomyosarcoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Macrocephaly&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Pilocytic Astrocytoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Optic Nerve Glioma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Neuropathy&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Duodenal Neuroendocrine Tumor G1&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ampulla of Vater Neuroendocrine Neoplasm&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Neurofibroma&apos;) and (&apos;Disease_Mapped_To_Chromosome&apos; some &apos;Chromosome 17&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;NF1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C119233</classIRI>
<classLabel>Physical Examination Findings of New or Worsening Heart Failure</classLabel>
<deletedAxiom>&apos;Physical Examination Findings of New or Worsening Heart Failure&apos; SubClassOf &apos;Clinical Test Result&apos;</deletedAxiom>
<newAxiom>&apos;Physical Examination Findings of New or Worsening Heart Failure&apos; SubClassOf &apos;Physical Exam Result&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158531</classIRI>
<classLabel>X-Linked Hyper-IgM Syndrome</classLabel>
<newAxiom>&apos;X-Linked Hyper-IgM Syndrome&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;CD40LG Gene&apos;</newAxiom>
<newAxiom>&apos;X-Linked Hyper-IgM Syndrome&apos; SubClassOf &apos;Immunodeficiency With Hyper-IgM&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3758</classIRI>
<classLabel>Hepatocellular Adenoma</classLabel>
<deletedAxiom>&apos;Hepatocellular Adenoma&apos; EquivalentTo &apos;Adenoma&apos; and &apos;Benign Liver and Intrahepatic Bile Duct Epithelial Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Liver&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Hepatic Tissue&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Hepatocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fibrosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemorrhagic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Gastrointestinal Tract&apos;)</deletedAxiom>
<newAxiom>&apos;Hepatocellular Adenoma&apos; EquivalentTo &apos;Digestive System Adenoma&apos; and &apos;Benign Liver and Intrahepatic Bile Duct Epithelial Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Liver&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Hepatic Tissue&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Hepatocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fibrosis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemorrhagic Change&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_Excludes_Primary_Anatomic_Site&apos; some &apos;Gastrointestinal Tract&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3764</classIRI>
<classLabel>Adenomatous Polyp</classLabel>
<deletedAxiom>&apos;Adenomatous Polyp&apos; EquivalentTo &apos;Adenoma&apos; and &apos;Neoplastic Polyp&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Glandular Cell&apos;)</deletedAxiom>
<newAxiom>&apos;Adenomatous Polyp&apos; EquivalentTo &apos;Digestive System Adenoma&apos; and &apos;Neoplastic Polyp&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Gastrointestinal Tract&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Glandular Cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87416</classIRI>
<classLabel>2,3-Dimercapto-1-Propanesulfonic Acid</classLabel>
<deletedAxiom>&apos;2,3-Dimercapto-1-Propanesulfonic Acid&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;2,3-Dimercapto-1-Propanesulfonic Acid&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3696</classIRI>
<classLabel>Subependymal Giant Cell Astrocytoma</classLabel>
<deletedAxiom>&apos;Subependymal Giant Cell Astrocytoma&apos; EquivalentTo &apos;Low Grade Astrocytic Tumor&apos; and &apos;Astrocytoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Lateral Ventricle&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Subependymal Tissue&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Large Ganglioid Astrocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Slow Growing Mass&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 1&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Giant Astrocyte&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Seizure&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Headache&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Mitotic Activity&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Calcification&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Perivascular Pseudopalisading&apos;)</deletedAxiom>
<newAxiom>&apos;Subependymal Giant Cell Astrocytoma&apos; EquivalentTo &apos;Low Grade Astrocytic Tumor&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Lateral Ventricle&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Subependymal Tissue&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Large Ganglioid Astrocyte&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Slow Growing Mass&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 1&apos;) and (&apos;Disease_May_Have_Abnormal_Cell&apos; some &apos;Giant Astrocyte&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Seizure&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Headache&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Mitotic Activity&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Calcification&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Perivascular Pseudopalisading&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158318</classIRI>
<classLabel>Radiological/Nuclear Challenge Agent Source Type</classLabel>
<deletedAxiom>&apos;Radiological/Nuclear Challenge Agent Source Type&apos; SubClassOf &apos;Radiation Source&apos;</deletedAxiom>
<newAxiom>&apos;Radiological/Nuclear Challenge Agent Source Type&apos; SubClassOf &apos;Type&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73030</classIRI>
<classLabel>Deferiprone</classLabel>
<deletedAxiom>&apos;Deferiprone&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Deferiprone&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3476</classIRI>
<classLabel>Li-Fraumeni Syndrome</classLabel>
<deletedAxiom>&apos;Li-Fraumeni Syndrome&apos; EquivalentTo &apos;Hereditary Neoplastic Syndrome&apos; and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Colorectal Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Medulloblastoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Choroid Plexus Neoplasm&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Gastric Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Astrocytic Tumor&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Osteosarcoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Soft Tissue Sarcoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Adrenal Cortex Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Malignant Breast Neoplasm&apos;) and (&apos;Disease_Mapped_To_Chromosome&apos; some &apos;Chromosome 17&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;TP53 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CHEK2 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Li-Fraumeni Syndrome&apos; EquivalentTo &apos;Hereditary Neoplastic Syndrome&apos; and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Soft Tissue Sarcoma&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124827</classIRI>
<classLabel>PSA Level</classLabel>
<deletedAxiom>&apos;PSA Level&apos; SubClassOf &apos;Property or Attribute&apos;</deletedAxiom>
<newAxiom>&apos;PSA Level&apos; SubClassOf &apos;Quantitative Concept&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48384</classIRI>
<classLabel>Deferasirox</classLabel>
<deletedAxiom>&apos;Deferasirox&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Deferasirox&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3994</classIRI>
<classLabel>Stage IV Colon Cancer AJCC v6</classLabel>
<deletedAxiom>&apos;Stage IV Colon Cancer AJCC v6&apos; EquivalentTo &apos;Stage IV Colorectal Cancer AJCC v6&apos; and &apos;Colon Cancer by AJCC v6 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Stage IV Colon Cancer AJCC v6&apos; EquivalentTo &apos;Stage IV Colorectal Cancer AJCC v6&apos; and &apos;Colon Cancer by AJCC v6 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73477</classIRI>
<classLabel>Emulsifier</classLabel>
<deletedAxiom>&apos;Emulsifier&apos; SubClassOf &apos;Substance&apos;</deletedAxiom>
<newAxiom>&apos;Emulsifier&apos; SubClassOf &apos;Pharmaceutical Excipient&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C111009</classIRI>
<classLabel>Someone to Give You Information to Help You Understand a Situation</classLabel>
<newAxiom>&apos;Someone to Give You Information to Help You Understand a Situation&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C111059</classIRI>
<classLabel>Able to Read Like They Used To</classLabel>
<newAxiom>&apos;Able to Read Like They Used To&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176426</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125328</classIRI>
<classLabel>Usual Severity Feeling of I Don&apos;t Look Like Myself</classLabel>
<newAxiom>&apos;Usual Severity Feeling of I Don&apos;t Look Like Myself&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125507</classIRI>
<classLabel>Medical Care I Have Been Receiving is Just About Perfect</classLabel>
<deletedAxiom>&apos;Medical Care I Have Been Receiving is Just About Perfect&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Medical Care I Have Been Receiving is Just About Perfect&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125509</classIRI>
<classLabel>Confident That I Can Get the Medical Care I Need Without Being Set Back Financially</classLabel>
<newAxiom>&apos;Confident That I Can Get the Medical Care I Need Without Being Set Back Financially&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125506</classIRI>
<classLabel>Doctor&apos;s Office Has Everything Needed to Provide Complete Medical Care</classLabel>
<newAxiom>&apos;Doctor&apos;s Office Has Everything Needed to Provide Complete Medical Care&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125520</classIRI>
<classLabel>Find it Hard to Get an Appointment for Medical Care Right Away</classLabel>
<newAxiom>&apos;Find it Hard to Get an Appointment for Medical Care Right Away&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125516</classIRI>
<classLabel>Those Providing Medical Care Sometimes Hurry Too Much When They Treat Me</classLabel>
<deletedAxiom>&apos;Those Providing Medical Care Sometimes Hurry Too Much When They Treat Me&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Those Providing Medical Care Sometimes Hurry Too Much When They Treat Me&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125511</classIRI>
<classLabel>Have to Pay More of My Medical Care Than I Can Afford</classLabel>
<deletedAxiom>&apos;Have to Pay More of My Medical Care Than I Can Afford&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Have to Pay More of My Medical Care Than I Can Afford&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125513</classIRI>
<classLabel>Wait for Emergency Treatment is Too Long Where I Get Medical Care</classLabel>
<newAxiom>&apos;Wait for Emergency Treatment is Too Long Where I Get Medical Care&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125521</classIRI>
<classLabel>Dissatisfied With Some Things About the Medical Care I Receive</classLabel>
<newAxiom>&apos;Dissatisfied With Some Things About the Medical Care I Receive&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125522</classIRI>
<classLabel>Able to Get Medical Care Whenever I Need It</classLabel>
<newAxiom>&apos;Able to Get Medical Care Whenever I Need It&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150438</classIRI>
<classLabel>Activating NTRK Family Fusion Gene Mutation</classLabel>
<newAxiom>&apos;Activating NTRK Family Fusion Gene Mutation&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176689</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150439</classIRI>
<classLabel>Activating NTRK Family Point Mutation</classLabel>
<deletedAxiom>&apos;Activating NTRK Family Point Mutation&apos; SubClassOf &apos;NTRK Family Gene Mutation&apos;</deletedAxiom>
<newAxiom>&apos;Activating NTRK Family Point Mutation&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176689</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125414</classIRI>
<classLabel>Don&apos;t Look Like Myself</classLabel>
<deletedAxiom>&apos;Don&apos;t Look Like Myself&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Don&apos;t Look Like Myself&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125070</classIRI>
<classLabel>Dissatisfied</classLabel>
<deletedAxiom>&apos;Dissatisfied&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Dissatisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125071</classIRI>
<classLabel>Uncertain if Satisfied or Dissatisfied</classLabel>
<deletedAxiom>&apos;Uncertain if Satisfied or Dissatisfied&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Uncertain if Satisfied or Dissatisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125072</classIRI>
<classLabel>Satisfied</classLabel>
<deletedAxiom>&apos;Satisfied&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Satisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125038</classIRI>
<classLabel>Ability to Have An Erection</classLabel>
<newAxiom>&apos;Ability to Have An Erection&apos; SubClassOf &apos;Sex Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C164301</classIRI>
<classLabel>Propel Wheelchair</classLabel>
<deletedAxiom>&apos;Propel Wheelchair&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Propel Wheelchair&apos; SubClassOf &apos;Play or Do Physical Activity Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C164305</classIRI>
<classLabel>Needs Help to Walk on Level Surface</classLabel>
<newAxiom>&apos;Needs Help to Walk on Level Surface&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C164306</classIRI>
<classLabel>Independent Walking on Level Surface</classLabel>
<newAxiom>&apos;Independent Walking on Level Surface&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C130975</classIRI>
<classLabel>Usually Need Help from Another Person for Walking</classLabel>
<newAxiom>&apos;Usually Need Help from Another Person for Walking&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C130963</classIRI>
<classLabel>Walker Usually Used</classLabel>
<deletedAxiom>&apos;Walker Usually Used&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Walker Usually Used&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C164122</classIRI>
<classLabel>Not At All Satisfied</classLabel>
<deletedAxiom>&apos;Not At All Satisfied&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Not At All Satisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C105884</classIRI>
<classLabel>Like My Body Appearance</classLabel>
<deletedAxiom>&apos;Like My Body Appearance&apos; SubClassOf &apos;Findings-Based Question&apos;</deletedAxiom>
<newAxiom>&apos;Like My Body Appearance&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C164046</classIRI>
<classLabel>Vascular Invasion Negative</classLabel>
<deletedAxiom>&apos;Vascular Invasion Negative&apos; SubClassOf &apos;Morphologic Finding&apos;</deletedAxiom>
<newAxiom>&apos;Vascular Invasion Negative&apos; SubClassOf &apos;Absence of Invasion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C139012</classIRI>
<classLabel>Breast Implant-Associated Anaplastic Large Cell Lymphoma</classLabel>
<deletedAxiom>&apos;Breast Implant-Associated Anaplastic Large Cell Lymphoma&apos; EquivalentTo &apos;Anaplastic Large Cell Lymphoma, ALK-Negative&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Breast&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Breast Implant-Related Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Breast Implant-Associated Anaplastic Large Cell Lymphoma&apos; EquivalentTo &apos;Anaplastic Large Cell Lymphoma, ALK-Negative&apos; and &apos;Breast T-Cell Non-Hodgkin Lymphoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Breast Implant-Related Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C119987</classIRI>
<classLabel>Had No Pain</classLabel>
<deletedAxiom>&apos;Had No Pain&apos; SubClassOf &apos;Have Symptom or Condition Question&apos;</deletedAxiom>
<newAxiom>&apos;Had No Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54581</classIRI>
<classLabel>Intestinal Hemorrhage</classLabel>
<deletedAxiom>&apos;Intestinal Hemorrhage&apos; SubClassOf &apos;Lower Gastrointestinal Hemorrhage&apos;</deletedAxiom>
<newAxiom>&apos;Intestinal Hemorrhage&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118264</classIRI>
<classLabel>Difficulty Absent</classLabel>
<deletedAxiom>&apos;Difficulty Absent&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Difficulty Absent&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118265</classIRI>
<classLabel>Worst Imaginable Difficulty</classLabel>
<newAxiom>&apos;Worst Imaginable Difficulty&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40259</classIRI>
<classLabel>Vaginal Villous Adenoma</classLabel>
<deletedAxiom>&apos;Vaginal Villous Adenoma&apos; EquivalentTo &apos;Vaginal Adenoma&apos; and &apos;Villous Adenoma&apos;</deletedAxiom>
<newAxiom>&apos;Vaginal Villous Adenoma&apos; EquivalentTo &apos;Vaginal Adenoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Villous Pattern&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Tubular Pattern&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40257</classIRI>
<classLabel>Vaginal Tubular Adenoma</classLabel>
<deletedAxiom>&apos;Vaginal Tubular Adenoma&apos; EquivalentTo &apos;Vaginal Adenoma&apos; and &apos;Tubular Adenoma&apos;</deletedAxiom>
<newAxiom>&apos;Vaginal Tubular Adenoma&apos; EquivalentTo &apos;Vaginal Adenoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Tubular Pattern&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Villous Pattern&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40258</classIRI>
<classLabel>Vaginal Tubulovillous Adenoma</classLabel>
<deletedAxiom>&apos;Vaginal Tubulovillous Adenoma&apos; EquivalentTo &apos;Vaginal Adenoma&apos; and &apos;Tubulovillous Adenoma&apos;</deletedAxiom>
<newAxiom>&apos;Vaginal Tubulovillous Adenoma&apos; EquivalentTo &apos;Vaginal Adenoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Tubular Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Villous Pattern&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40400</classIRI>
<classLabel>Breast Granular Cell Tumor</classLabel>
<deletedAxiom>&apos;Breast Granular Cell Tumor&apos; EquivalentTo &apos;Breast Neoplasm&apos; and &apos;Granular Cell Tumor&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Breast&apos;)</deletedAxiom>
<newAxiom>&apos;Breast Granular Cell Tumor&apos; EquivalentTo &apos;Granular Cell Tumor&apos; and &apos;Breast Soft Tissue Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157576</classIRI>
<classLabel>Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate</classLabel>
<newAxiom>&apos;Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;TP63 Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74001</classIRI>
<classLabel>Tiomolibdate Diammonium</classLabel>
<deletedAxiom>&apos;Tiomolibdate Diammonium&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Tiomolibdate Diammonium&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40801</classIRI>
<classLabel>Intercellular Transport Process</classLabel>
<deletedAxiom>&apos;Intercellular Transport Process&apos; SubClassOf &apos;Other Finding&apos;</deletedAxiom>
<newAxiom>&apos;Intercellular Transport Process&apos; SubClassOf &apos;Multicellular Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40965</classIRI>
<classLabel>CHEK2 Gene</classLabel>
<newAxiom>&apos;CHEK2 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176588</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157036</classIRI>
<classLabel>Zero to Ten Seconds Walking</classLabel>
<deletedAxiom>&apos;Zero to Ten Seconds Walking&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Zero to Ten Seconds Walking&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157037</classIRI>
<classLabel>Eleven to Twenty Seconds Walking</classLabel>
<deletedAxiom>&apos;Eleven to Twenty Seconds Walking&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Eleven to Twenty Seconds Walking&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157038</classIRI>
<classLabel>Greater Than Twenty Seconds Walking, or Patient Unwilling, or Requires Assistance Walking</classLabel>
<deletedAxiom>&apos;Greater Than Twenty Seconds Walking, or Patient Unwilling, or Requires Assistance Walking&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Greater Than Twenty Seconds Walking, or Patient Unwilling, or Requires Assistance Walking&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74576</classIRI>
<classLabel>Pentetate Calcium Trisodium</classLabel>
<deletedAxiom>&apos;Pentetate Calcium Trisodium&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Pentetate Calcium Trisodium&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137843</classIRI>
<classLabel>Have to Read Something Several Times to Understand</classLabel>
<deletedAxiom>&apos;Have to Read Something Several Times to Understand&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Have to Read Something Several Times to Understand&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176426</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C137844</classIRI>
<classLabel>Current Difficulty Reading and Following Complex Instructions</classLabel>
<newAxiom>&apos;Current Difficulty Reading and Following Complex Instructions&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176426</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162782</classIRI>
<classLabel>Non-Metastatic Breast Carcinoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Breast Carcinoma&apos; EquivalentTo &apos;Breast Carcinoma&apos; and &apos;Non-Metastatic Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Breast Carcinoma&apos; EquivalentTo &apos;Breast Carcinoma&apos; and &apos;Localized Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124220</classIRI>
<classLabel>Often Have Persistent and Severe Coughing Spells</classLabel>
<deletedAxiom>&apos;Often Have Persistent and Severe Coughing Spells&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Often Have Persistent and Severe Coughing Spells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176248</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124216</classIRI>
<classLabel>Seldom Cough</classLabel>
<deletedAxiom>&apos;Seldom Cough&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Seldom Cough&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176248</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124217</classIRI>
<classLabel>Have Occasional Cough</classLabel>
<deletedAxiom>&apos;Have Occasional Cough&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Have Occasional Cough&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176248</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124218</classIRI>
<classLabel>Often Cough</classLabel>
<deletedAxiom>&apos;Often Cough&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Often Cough&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176248</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124219</classIRI>
<classLabel>Often Cough and Have Occasionally Severe Coughing Spells</classLabel>
<deletedAxiom>&apos;Often Cough and Have Occasionally Severe Coughing Spells&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Often Cough and Have Occasionally Severe Coughing Spells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176248</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124212</classIRI>
<classLabel>Worried and Frightened About Things</classLabel>
<newAxiom>&apos;Worried and Frightened About Things&apos; SubClassOf &apos;Worry Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C60639</classIRI>
<classLabel>Rectal Small Cell Neuroendocrine Carcinoma</classLabel>
<deletedAxiom>&apos;Rectal Small Cell Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Colorectal Small Cell Neuroendocrine Carcinoma&apos; and &apos;Rectal Neuroendocrine Neoplasm&apos; and &apos;Rectal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Rectal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Rectal Small Cell Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Colorectal Small Cell Neuroendocrine Carcinoma&apos; and &apos;Rectal Neuroendocrine Neoplasm&apos; and &apos;Rectal Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124176</classIRI>
<classLabel>Have Very Mild Pain</classLabel>
<deletedAxiom>&apos;Have Very Mild Pain&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Have Very Mild Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124177</classIRI>
<classLabel>Have Mildly Distressing Pain</classLabel>
<deletedAxiom>&apos;Have Mildly Distressing Pain&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Have Mildly Distressing Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124178</classIRI>
<classLabel>Usually Have Fairly Intense Pain</classLabel>
<deletedAxiom>&apos;Usually Have Fairly Intense Pain&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Usually Have Fairly Intense Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124171</classIRI>
<classLabel>Have Pain Once in a While</classLabel>
<deletedAxiom>&apos;Have Pain Once in a While&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Have Pain Once in a While&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124172</classIRI>
<classLabel>Have Pain Several Times a Week</classLabel>
<deletedAxiom>&apos;Have Pain Several Times a Week&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Have Pain Several Times a Week&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124173</classIRI>
<classLabel>Usually in Some Degree of Pain</classLabel>
<deletedAxiom>&apos;Usually in Some Degree of Pain&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Usually in Some Degree of Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124174</classIRI>
<classLabel>In Some Degree of Pain Almost Constantly</classLabel>
<deletedAxiom>&apos;In Some Degree of Pain Almost Constantly&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;In Some Degree of Pain Almost Constantly&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124170</classIRI>
<classLabel>Almost Never Have Pain</classLabel>
<deletedAxiom>&apos;Almost Never Have Pain&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Almost Never Have Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176245</newAxiom>
<newAxiom>&apos;Almost Never Have Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124168</classIRI>
<classLabel>Have Difficulty Getting to Sleep and Staying Asleep</classLabel>
<deletedAxiom>&apos;Have Difficulty Getting to Sleep and Staying Asleep&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Have Difficulty Getting to Sleep and Staying Asleep&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
<newAxiom>&apos;Have Difficulty Getting to Sleep and Staying Asleep&apos; SubClassOf &apos;Sleep Responses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124180</classIRI>
<classLabel>Have Almost Unbearable Pain</classLabel>
<deletedAxiom>&apos;Have Almost Unbearable Pain&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Have Almost Unbearable Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C124179</classIRI>
<classLabel>Have Very Intense Pain</classLabel>
<deletedAxiom>&apos;Have Very Intense Pain&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Have Very Intense Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C94526</classIRI>
<classLabel>Tumor Mass Fragmentation</classLabel>
<deletedAxiom>&apos;Tumor Mass Fragmentation&apos; SubClassOf &apos;Abnormal Finding&apos;</deletedAxiom>
<newAxiom>&apos;Tumor Mass Fragmentation&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138080</classIRI>
<classLabel>Never Have Erection When Want One</classLabel>
<newAxiom>&apos;Never Have Erection When Want One&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176245</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138009</classIRI>
<classLabel>About Half the Time</classLabel>
<deletedAxiom>&apos;About Half the Time&apos; SubClassOf &apos;Temporal Frequency&apos;</deletedAxiom>
<newAxiom>&apos;About Half the Time&apos; SubClassOf &apos;Time Frequency Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138011</classIRI>
<classLabel>Mostly Dissatisfied</classLabel>
<deletedAxiom>&apos;Mostly Dissatisfied&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Mostly Dissatisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C94796</classIRI>
<classLabel>Locally Recurrent Malignant Neoplasm</classLabel>
<deletedAxiom>&apos;Locally Recurrent Malignant Neoplasm&apos; EquivalentTo &apos;Recurrent Malignant Neoplasm&apos; and &apos;Localized Malignant Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Localized Disease&apos;)</deletedAxiom>
<newAxiom>&apos;Locally Recurrent Malignant Neoplasm&apos; EquivalentTo &apos;Recurrent Malignant Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176551)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104478</classIRI>
<classLabel>Agree</classLabel>
<deletedAxiom>&apos;Agree&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Agree&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176244</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104479</classIRI>
<classLabel>Disagree</classLabel>
<deletedAxiom>&apos;Disagree&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Disagree&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176244</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118844</classIRI>
<classLabel>Hypohidrotic Ectodermal Dysplasia with Immune Deficiency</classLabel>
<newAxiom>&apos;Hypohidrotic Ectodermal Dysplasia with Immune Deficiency&apos; SubClassOf &apos;Immunodeficiency Syndrome&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104307</classIRI>
<classLabel>Difficulty Concentrating Reading Newspaper or Watching Television</classLabel>
<newAxiom>&apos;Difficulty Concentrating Reading Newspaper or Watching Television&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176426</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104320</classIRI>
<classLabel>Look Flushed or Red</classLabel>
<newAxiom>&apos;Look Flushed or Red&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104374</classIRI>
<classLabel>Have Problem Receiving Adequate Disease and Treatment Information</classLabel>
<newAxiom>&apos;Have Problem Receiving Adequate Disease and Treatment Information&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118663</classIRI>
<classLabel>Have Trouble Remembering New Information</classLabel>
<newAxiom>&apos;Have Trouble Remembering New Information&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118730</classIRI>
<classLabel>Have Been Told that I Have Trouble Remembering Information</classLabel>
<newAxiom>&apos;Have Been Told that I Have Trouble Remembering Information&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5543</classIRI>
<classLabel>Cecum Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Cecum Adenocarcinoma&apos; EquivalentTo &apos;Cecum Carcinoma&apos; and &apos;Colon Adenocarcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Cecum Adenocarcinoma&apos; EquivalentTo &apos;Cecum Carcinoma&apos; and &apos;Colon Adenocarcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C166171</classIRI>
<classLabel>Non-Metastatic Esophageal Carcinoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Esophageal Carcinoma&apos; EquivalentTo &apos;Esophageal Carcinoma&apos; and &apos;Non-Metastatic Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Esophageal Carcinoma&apos; EquivalentTo &apos;Esophageal Carcinoma&apos; and &apos;Localized Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C166153</classIRI>
<classLabel>Autosomal Recessive Severe Congenital Neutropenia</classLabel>
<deletedAxiom>&apos;Autosomal Recessive Severe Congenital Neutropenia&apos; SubClassOf &apos;Severe Congenital Neutropenia&apos;</deletedAxiom>
<newAxiom>&apos;Autosomal Recessive Severe Congenital Neutropenia&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176624</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C166217</classIRI>
<classLabel>Have Difficulties Using Smartphones or Tablets</classLabel>
<deletedAxiom>&apos;Have Difficulties Using Smartphones or Tablets&apos; SubClassOf &apos;Ability Answer&apos;</deletedAxiom>
<newAxiom>&apos;Have Difficulties Using Smartphones or Tablets&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80963</classIRI>
<classLabel>Ditiocarb Sodium</classLabel>
<deletedAxiom>&apos;Ditiocarb Sodium&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Ditiocarb Sodium&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107586</classIRI>
<classLabel>Interleukin-10 Receptor Subunit Alpha</classLabel>
<deletedAxiom>&apos;Interleukin-10 Receptor Subunit Alpha&apos; EquivalentTo &apos;Cytokine Receptor&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;IL10 Anti-inflammatory Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;IL22 Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cytokine-Cytokine Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Jak-STAT Signaling Pathway&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immune Response Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Receptor Signaling&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Interleukin Signaling Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;IL10RA Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Interleukin-10 Receptor Subunit Alpha&apos; EquivalentTo &apos;Cytokine Receptor&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;IL10 Anti-inflammatory Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;IL22 Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cytokine-Cytokine Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Jak-STAT Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176754) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immune Response Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Receptor Signaling&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Interleukin Signaling Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;IL10RA Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16424</classIRI>
<classLabel>Child Abuse and Neglect</classLabel>
<deletedAxiom>&apos;Child Abuse and Neglect&apos; SubClassOf &apos;Other Finding&apos;</deletedAxiom>
<newAxiom>&apos;Child Abuse and Neglect&apos; SubClassOf &apos;Event&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107643</classIRI>
<classLabel>Not Firm Enough for Sexual Activity</classLabel>
<deletedAxiom>&apos;Not Firm Enough for Sexual Activity&apos; SubClassOf &apos;General Qualifier&apos;</deletedAxiom>
<deletedAxiom>&apos;Not Firm Enough for Sexual Activity&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Not Firm Enough for Sexual Activity&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176252</newAxiom>
<newAxiom>&apos;Not Firm Enough for Sexual Activity&apos; SubClassOf &apos;Erection Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5810</classIRI>
<classLabel>Stage IV Small Intestinal Cancer AJCC v7</classLabel>
<deletedAxiom>&apos;Stage IV Small Intestinal Cancer AJCC v7&apos; EquivalentTo &apos;Small Intestinal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage IV&apos;)</deletedAxiom>
<newAxiom>&apos;Stage IV Small Intestinal Cancer AJCC v7&apos; EquivalentTo &apos;Small Intestinal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage IV&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5809</classIRI>
<classLabel>Stage III Small Intestinal Cancer AJCC v7</classLabel>
<deletedAxiom>&apos;Stage III Small Intestinal Cancer AJCC v7&apos; EquivalentTo &apos;Small Intestinal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage III&apos;)</deletedAxiom>
<newAxiom>&apos;Stage III Small Intestinal Cancer AJCC v7&apos; EquivalentTo &apos;Small Intestinal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage III&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5808</classIRI>
<classLabel>Stage II Small Intestinal Cancer AJCC v7</classLabel>
<deletedAxiom>&apos;Stage II Small Intestinal Cancer AJCC v7&apos; EquivalentTo &apos;Small Intestinal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage II&apos;)</deletedAxiom>
<newAxiom>&apos;Stage II Small Intestinal Cancer AJCC v7&apos; EquivalentTo &apos;Small Intestinal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage II&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5807</classIRI>
<classLabel>Stage I Small Intestinal Cancer AJCC v7</classLabel>
<deletedAxiom>&apos;Stage I Small Intestinal Cancer AJCC v7&apos; EquivalentTo &apos;Small Intestinal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage I&apos;)</deletedAxiom>
<newAxiom>&apos;Stage I Small Intestinal Cancer AJCC v7&apos; EquivalentTo &apos;Small Intestinal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage I&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C146823</classIRI>
<classLabel>Autologous iCASP9-CD19-expressing T-Lymphocytes</classLabel>
<deletedAxiom>&apos;Autologous iCASP9-CD19-expressing T-Lymphocytes&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous iCASP9-CD19-expressing T-Lymphocytes&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5672</classIRI>
<classLabel>Lung Large Cell Neuroendocrine Carcinoma</classLabel>
<deletedAxiom>&apos;Lung Large Cell Neuroendocrine Carcinoma&apos; EquivalentTo &apos;High Grade Lung Neuroendocrine Neoplasm&apos; and &apos;Lung Carcinoma&apos; and &apos;Large Cell Neuroendocrine Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Peripheral Nuclear Palisading&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Nuclear Molding&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;More than 10 Mitoses per 10HPF&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Dyspnea&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemoptysis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Trabecular Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Rosette Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cough&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Sheet-Like Growth Pattern&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;RB1 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;FGFR1 Gene Amplification&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;C-KIT Tyrosine Kinase Protein Overexpression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CDKN2A Gene Deletion&apos;)</deletedAxiom>
<newAxiom>&apos;Lung Large Cell Neuroendocrine Carcinoma&apos; EquivalentTo &apos;High Grade Lung Neuroendocrine Neoplasm&apos; and &apos;Large Cell Neuroendocrine Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Peripheral Nuclear Palisading&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Nuclear Molding&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;More than 10 Mitoses per 10HPF&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Dyspnea&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemoptysis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Trabecular Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Rosette Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cough&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Sheet-Like Growth Pattern&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;RB1 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;FGFR1 Gene Amplification&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;C-KIT Tyrosine Kinase Protein Overexpression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CDKN2A Gene Deletion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132221</classIRI>
<classLabel>Not Sexually Active</classLabel>
<deletedAxiom>&apos;Not Sexually Active&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Not Sexually Active&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176252</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132258</classIRI>
<classLabel>STING Agonist MK-1454</classLabel>
<deletedAxiom>&apos;STING Agonist MK-1454&apos; SubClassOf &apos;Antineoplastic Immunomodulating Agent&apos;</deletedAxiom>
<newAxiom>&apos;STING Agonist MK-1454&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176586</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171822</classIRI>
<classLabel>Deferitazole Magnesium</classLabel>
<deletedAxiom>&apos;Deferitazole Magnesium&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Deferitazole Magnesium&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C89992</classIRI>
<classLabel>Stage II Rectosigmoid Cancer AJCC v7</classLabel>
<deletedAxiom>&apos;Stage II Rectosigmoid Cancer AJCC v7&apos; EquivalentTo &apos;Stage II Colorectal Cancer AJCC v7&apos; and &apos;Rectosigmoid Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;)</deletedAxiom>
<newAxiom>&apos;Stage II Rectosigmoid Cancer AJCC v7&apos; EquivalentTo &apos;Stage II Colorectal Cancer AJCC v7&apos; and &apos;Rectosigmoid Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C89994</classIRI>
<classLabel>Stage III Colorectal Cancer AJCC v7</classLabel>
<deletedAxiom>&apos;Stage III Colorectal Cancer AJCC v7&apos; EquivalentTo &apos;Colorectal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage III&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;)</deletedAxiom>
<newAxiom>&apos;Stage III Colorectal Cancer AJCC v7&apos; EquivalentTo &apos;Colorectal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage III&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C89997</classIRI>
<classLabel>Stage III Rectosigmoid Cancer AJCC v7</classLabel>
<deletedAxiom>&apos;Stage III Rectosigmoid Cancer AJCC v7&apos; EquivalentTo &apos;Stage III Colorectal Cancer AJCC v7&apos; and &apos;Rectosigmoid Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;)</deletedAxiom>
<newAxiom>&apos;Stage III Rectosigmoid Cancer AJCC v7&apos; EquivalentTo &apos;Stage III Colorectal Cancer AJCC v7&apos; and &apos;Rectosigmoid Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C89999</classIRI>
<classLabel>Stage IV Colon Cancer AJCC v7</classLabel>
<deletedAxiom>&apos;Stage IV Colon Cancer AJCC v7&apos; EquivalentTo &apos;Stage IV Colorectal Cancer AJCC v7&apos; and &apos;Colon Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Stage IV Colon Cancer AJCC v7&apos; EquivalentTo &apos;Stage IV Colorectal Cancer AJCC v7&apos; and &apos;Colon Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C89989</classIRI>
<classLabel>Stage II Colorectal Cancer AJCC v7</classLabel>
<deletedAxiom>&apos;Stage II Colorectal Cancer AJCC v7&apos; EquivalentTo &apos;Colorectal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage II&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;)</deletedAxiom>
<newAxiom>&apos;Stage II Colorectal Cancer AJCC v7&apos; EquivalentTo &apos;Colorectal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage II&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36037</classIRI>
<classLabel>Non-Metastatic Neoplasm</classLabel>
<deletedAxiom>&apos;Non-Metastatic Neoplasm&apos; EquivalentTo &apos;Neoplasm by Special Category&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Neoplasm&apos; EquivalentTo &apos;Neoplasm by Special Category&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Localized Disease&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Primary Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176551) and (&apos;Disease_Excludes_Finding&apos; some &apos;Metastatic Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36101</classIRI>
<classLabel>BRCA2 Syndrome</classLabel>
<deletedAxiom>&apos;BRCA2 Syndrome&apos; EquivalentTo &apos;Hereditary Breast and Ovarian Cancer Syndrome&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;BRCA2 Gene Mutation&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Melanoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Gallbladder Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Pancreatic Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Fallopian Tube Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Prostate Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ovarian Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Gastric Carcinoma&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BRCA2 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;BRCA2 Syndrome&apos; EquivalentTo &apos;Hereditary Breast and Ovarian Cancer Syndrome&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Deleterious BRCA2 Gene Mutation&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Melanoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Gallbladder Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Pancreatic Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Fallopian Tube Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Prostate Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ovarian Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Gastric Carcinoma&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BRCA2 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36100</classIRI>
<classLabel>BRCA1 Syndrome</classLabel>
<deletedAxiom>&apos;BRCA1 Syndrome&apos; EquivalentTo &apos;Hereditary Breast and Ovarian Cancer Syndrome&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;BRCA1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Hepatocellular Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Fallopian Tube Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Primary Peritoneal Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ovarian Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Colon Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Endometrial Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Cervical Carcinoma&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BRCA1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;BRCA1 Syndrome&apos; EquivalentTo &apos;Hereditary Breast and Ovarian Cancer Syndrome&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Deleterious BRCA1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Hepatocellular Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Fallopian Tube Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Primary Peritoneal Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Breast Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ovarian Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Colon Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Endometrial Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Cervical Carcinoma&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;BRCA1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36207</classIRI>
<classLabel>Digestive System Adenoma</classLabel>
<deletedAxiom>&apos;Digestive System Adenoma&apos; EquivalentTo &apos;Adenoma&apos; and &apos;Benign Digestive System Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Gastrointestinal Tract&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Glandular Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Dysplasia&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Intraepithelial Neoplasia&apos;)</deletedAxiom>
<newAxiom>&apos;Digestive System Adenoma&apos; EquivalentTo &apos;Adenoma&apos; and &apos;Benign Digestive System Neoplasm&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Glandular Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Dysplasia&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Well-Circumscribed Lesion&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Intraepithelial Neoplasia&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172057</classIRI>
<classLabel>Autologous Anti-CD19/CD20 Bispecific Nanobody-based CAR-T cells</classLabel>
<newAxiom>&apos;Autologous Anti-CD19/CD20 Bispecific Nanobody-based CAR-T cells&apos; SubClassOf &apos;Therapeutic Autologous Lymphocytes&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113331</classIRI>
<classLabel>DKK1-Neutralizing Monoclonal Antibody DKN-01</classLabel>
<deletedAxiom>&apos;DKK1-Neutralizing Monoclonal Antibody DKN-01&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;DKK1-Neutralizing Monoclonal Antibody DKN-01&apos; SubClassOf &apos;Monoclonal Antibody&apos;</deletedAxiom>
<newAxiom>&apos;DKK1-Neutralizing Monoclonal Antibody DKN-01&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61987</classIRI>
<classLabel>Trientine Hydrochloride</classLabel>
<deletedAxiom>&apos;Trientine Hydrochloride&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Trientine Hydrochloride&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61953</classIRI>
<classLabel>Succimer</classLabel>
<deletedAxiom>&apos;Succimer&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Succimer&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95892</classIRI>
<classLabel>PSMA-targeted Docetaxel Nanoparticles BIND-014</classLabel>
<newAxiom>&apos;PSMA-targeted Docetaxel Nanoparticles BIND-014&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81328</classIRI>
<classLabel>Body Weight</classLabel>
<newAxiom>&apos;Body Weight&apos; SubClassOf &apos;Personal Attribute&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C166785</classIRI>
<classLabel>Emeramide</classLabel>
<deletedAxiom>&apos;Emeramide&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Emeramide&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C166753</classIRI>
<classLabel>Deferitazole</classLabel>
<deletedAxiom>&apos;Deferitazole&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Deferitazole&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C152051</classIRI>
<classLabel>AP-2 Complex Subunit Beta</classLabel>
<deletedAxiom>&apos;AP-2 Complex Subunit Beta&apos; EquivalentTo &apos;Transport Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Huntington&apos;s Disease Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Endocytosis Pathway&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Coated Pit&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Proline-Rich Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Endocytotic Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intracellular Transport&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;AP2B1 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;AP-2 Complex Subunit Beta&apos; EquivalentTo &apos;Transport Protein&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Huntington&apos;s Disease Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Endocytosis Pathway&apos;) and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Scaffolding Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Coated Pit&apos;) and (&apos;Gene_Product_Has_Structural_Domain_Or_Motif&apos; some &apos;Proline-Rich Domain&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Endocytotic Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intracellular Transport&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;AP2B1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C127062</classIRI>
<classLabel>Never Smoked Cigarettes Regularly</classLabel>
<newAxiom>&apos;Never Smoked Cigarettes Regularly&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176245</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17359</classIRI>
<classLabel>TP53 Gene</classLabel>
<deletedAxiom>&apos;TP53 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some &apos;Li-Fraumeni Syndrome&apos;</deletedAxiom>
<newAxiom>&apos;TP53 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176587</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6169</classIRI>
<classLabel>Urethral Condyloma</classLabel>
<deletedAxiom>&apos;Urethral Condyloma&apos; EquivalentTo &apos;Condyloma&apos; and &apos;Urethra Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Urethra&apos;)</deletedAxiom>
<newAxiom>&apos;Urethral Condyloma&apos; EquivalentTo &apos;Condyloma&apos; and &apos;Benign Urethral Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81983</classIRI>
<classLabel>Carcinoembryonic Antigen Measurement</classLabel>
<newAxiom>&apos;Carcinoembryonic Antigen Measurement&apos; SubClassOf &apos;Protein or Enzyme Type Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4133</classIRI>
<classLabel>Tubular Adenoma</classLabel>
<deletedAxiom>&apos;Tubular Adenoma&apos; EquivalentTo &apos;Adenoma&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Glandular Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Tubular Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Exophytic Polypoid Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Dysplasia&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Intraepithelial Neoplasia&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Villous Pattern&apos;)</deletedAxiom>
<newAxiom>&apos;Tubular Adenoma&apos; EquivalentTo &apos;Digestive System Adenoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Gastrointestinal Tract&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Glandular Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Tubular Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Exophytic Polypoid Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Dysplasia&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Intraepithelial Neoplasia&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Villous Pattern&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4143</classIRI>
<classLabel>Tubulovillous Adenoma</classLabel>
<deletedAxiom>&apos;Tubulovillous Adenoma&apos; EquivalentTo &apos;Adenoma&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Glandular Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Tubular Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Villous Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Exophytic Polypoid Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Dysplasia&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Intraepithelial Neoplasia&apos;)</deletedAxiom>
<newAxiom>&apos;Tubulovillous Adenoma&apos; EquivalentTo &apos;Digestive System Adenoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Gastrointestinal Tract&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Neoplastic Glandular Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Tubular Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Villous Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Exophytic Polypoid Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Dysplasia&apos;) and (&apos;Disease_Has_Associated_Disease&apos; some &apos;Intraepithelial Neoplasia&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C42664</classIRI>
<classLabel>Flavor Excipient</classLabel>
<deletedAxiom>&apos;Flavor Excipient&apos; SubClassOf &apos;Pharmaceutical Excipient&apos;</deletedAxiom>
<newAxiom>&apos;Flavor Excipient&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176635</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C42658</classIRI>
<classLabel>Sweetener Excipient</classLabel>
<deletedAxiom>&apos;Sweetener Excipient&apos; SubClassOf &apos;Pharmaceutical Excipient&apos;</deletedAxiom>
<newAxiom>&apos;Sweetener Excipient&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176635</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C42656</classIRI>
<classLabel>Color Excipient</classLabel>
<deletedAxiom>&apos;Color Excipient&apos; SubClassOf &apos;Pharmaceutical Excipient&apos;</deletedAxiom>
<newAxiom>&apos;Color Excipient&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176635</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131214</classIRI>
<classLabel>Autologous iCasp9-deltaNGFR-CD19CAR-expressing T Cells</classLabel>
<deletedAxiom>&apos;Autologous iCasp9-deltaNGFR-CD19CAR-expressing T Cells&apos; SubClassOf &apos;Chimeric Antigen Receptor T-cells&apos;</deletedAxiom>
<newAxiom>&apos;Autologous iCasp9-deltaNGFR-CD19CAR-expressing T Cells&apos; SubClassOf &apos;Anti-CD19-targeting CAR-T Cells&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C106374</classIRI>
<classLabel>Charlson Comorbidity Index Derived from Chart Review</classLabel>
<deletedAxiom>&apos;Charlson Comorbidity Index Derived from Chart Review&apos; SubClassOf &apos;Clinical or Research Assessment Questionnaire&apos;</deletedAxiom>
<newAxiom>&apos;Charlson Comorbidity Index Derived from Chart Review&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176422</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4671</classIRI>
<classLabel>Breast Lymphoma</classLabel>
<deletedAxiom>&apos;Breast Lymphoma&apos; EquivalentTo &apos;Lymphoma by Site&apos; and &apos;Malignant Breast Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Breast&apos;) and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Mammary Gland Tissue&apos;)</deletedAxiom>
<newAxiom>&apos;Breast Lymphoma&apos; EquivalentTo &apos;Lymphoma by Site&apos; and &apos;Malignant Breast Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Breast&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76325</classIRI>
<classLabel>Birth Weight</classLabel>
<newAxiom>&apos;Birth Weight&apos; SubClassOf &apos;Personal Attribute&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76597</classIRI>
<classLabel>Deferitrin</classLabel>
<deletedAxiom>&apos;Deferitrin&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Deferitrin&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76602</classIRI>
<classLabel>Ranelic Acid</classLabel>
<deletedAxiom>&apos;Ranelic Acid&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Ranelic Acid&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C111817</classIRI>
<classLabel>Hyperpyrexia</classLabel>
<deletedAxiom>&apos;Hyperpyrexia&apos; SubClassOf &apos;Fever&apos;</deletedAxiom>
<newAxiom>&apos;Hyperpyrexia&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176698</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159926</classIRI>
<classLabel>Have Concerns About How You Look</classLabel>
<newAxiom>&apos;Have Concerns About How You Look&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4954</classIRI>
<classLabel>Non-Metastatic Malignant Brain Neoplasm</classLabel>
<deletedAxiom>&apos;Non-Metastatic Malignant Brain Neoplasm&apos; EquivalentTo &apos;Malignant Brain Neoplasm&apos; and &apos;Non-Metastatic Brain Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Malignant Brain Neoplasm&apos; EquivalentTo &apos;Malignant Brain Neoplasm&apos; and &apos;Non-Metastatic Brain Neoplasm&apos; and &apos;Localized Malignant Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4917</classIRI>
<classLabel>Lung Small Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Lung Small Cell Carcinoma&apos; EquivalentTo &apos;Small Cell Neuroendocrine Carcinoma&apos; and &apos;High Grade Lung Neuroendocrine Neoplasm&apos; and &apos;Lung Carcinoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bronchus&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Peripheral Nuclear Palisading&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Nuclear Molding&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;More than 10 Mitoses per 10HPF&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 5q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(13q14)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 19&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 17q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 3q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 5p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 18q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 17p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 3p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 10q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 4&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 6p&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Trabecular Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Rosette Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Sheet-Like Growth Pattern&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Paraneoplastic Syndrome&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PTEN Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;RB1 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;FGFR1 Gene Amplification&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NMYC Gene Amplification&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;C-KIT Tyrosine Kinase Protein Overexpression&apos;)</deletedAxiom>
<newAxiom>&apos;Lung Small Cell Carcinoma&apos; EquivalentTo &apos;Small Cell Neuroendocrine Carcinoma&apos; and &apos;High Grade Lung Neuroendocrine Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bronchus&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Peripheral Nuclear Palisading&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Nuclear Molding&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;More than 10 Mitoses per 10HPF&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 5q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;del(13q14)&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 19&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 20q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 17q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 3q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 8q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 5p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 18q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 17p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 3p&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 10q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 4&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 6p&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Trabecular Pattern&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Rosette Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Sheet-Like Growth Pattern&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Paraneoplastic Syndrome&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PTEN Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;RB1 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;FGFR1 Gene Amplification&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;NMYC Gene Amplification&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;C-KIT Tyrosine Kinase Protein Overexpression&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C111664</classIRI>
<classLabel>Some Problems Walking</classLabel>
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<newAxiom>&apos;Duodenal Carcinoma&apos; EquivalentTo &apos;Small Intestinal Carcinoma&apos; and &apos;Malignant Duodenal Neoplasm&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Duodenum&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
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<classLabel>Spinocerebellar Ataxia Type 7</classLabel>
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<classLabel>XIAP Deficiency</classLabel>
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<newAxiom>&apos;XIAP Deficiency&apos; SubClassOf &apos;X-Linked Lymphoproliferative Syndrome&apos;</newAxiom>
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<classLabel>Over Ninety Activity Hours</classLabel>
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<classLabel>Sixty-One to Ninety Activity Hours</classLabel>
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<classLabel>Two to Five Activity Hours</classLabel>
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<newAxiom>&apos;Two to Five Activity Hours&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176256</newAxiom>
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<classLabel>Eleven or More Activity Hours</classLabel>
<deletedAxiom>&apos;Eleven or More Activity Hours&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Eleven or More Activity Hours&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176256</newAxiom>
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<classLabel>Eleven to Twenty Activity Hours</classLabel>
<deletedAxiom>&apos;Eleven to Twenty Activity Hours&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Eleven to Twenty Activity Hours&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176256</newAxiom>
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<changedClass>
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<classLabel>Six to Ten Activity Hours</classLabel>
<deletedAxiom>&apos;Six to Ten Activity Hours&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Six to Ten Activity Hours&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176256</newAxiom>
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<classLabel>Seven to Ten Activity Hours</classLabel>
<deletedAxiom>&apos;Seven to Ten Activity Hours&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Seven to Ten Activity Hours&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176256</newAxiom>
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<changedClass>
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<classLabel>Four to Six Activity Hours</classLabel>
<deletedAxiom>&apos;Four to Six Activity Hours&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Four to Six Activity Hours&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176256</newAxiom>
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<classLabel>Two to Three Activity Hours</classLabel>
<deletedAxiom>&apos;Two to Three Activity Hours&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Two to Three Activity Hours&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176256</newAxiom>
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<classLabel>Easy or Casual Walking Pace</classLabel>
<deletedAxiom>&apos;Easy or Casual Walking Pace&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Easy or Casual Walking Pace&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
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<classLabel>Brisk Walking Pace</classLabel>
<deletedAxiom>&apos;Brisk Walking Pace&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Brisk Walking Pace&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
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<classLabel>Normal or Average Walking Pace</classLabel>
<deletedAxiom>&apos;Normal or Average Walking Pace&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Normal or Average Walking Pace&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
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<classLabel>Neutrophil-Activating Peptide 2 Measurement</classLabel>
<deletedAxiom>&apos;Neutrophil-Activating Peptide 2 Measurement&apos; SubClassOf &apos;Protein or Enzyme Type Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Neutrophil-Activating Peptide 2 Measurement&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126350</classIRI>
<classLabel>SH2D1A Deficiency</classLabel>
<deletedAxiom>&apos;SH2D1A Deficiency&apos; SubClassOf &apos;Immunodeficiency Syndrome&apos;</deletedAxiom>
<newAxiom>&apos;SH2D1A Deficiency&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165955</classIRI>
<classLabel>Chemokine (C-X-C Motif) Ligand 7 Measurement</classLabel>
<newAxiom>&apos;Chemokine (C-X-C Motif) Ligand 7 Measurement&apos; SubClassOf &apos;Protein or Enzyme Type Measurement&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126346</classIRI>
<classLabel>STAT1 Gain of Function</classLabel>
<deletedAxiom>&apos;STAT1 Gain of Function&apos; SubClassOf &apos;STAT Family Gene Mutation&apos;</deletedAxiom>
<deletedAxiom>&apos;STAT1 Gain of Function&apos; SubClassOf &apos;Molecular_Abnormality_Involves_Gene&apos; some &apos;STAT1 Gene&apos;</deletedAxiom>
<newAxiom>&apos;STAT1 Gain of Function&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176672</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165691</classIRI>
<classLabel>Doctor Helped Me Understand All Information</classLabel>
<newAxiom>&apos;Doctor Helped Me Understand All Information&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165655</classIRI>
<classLabel>STING Agonist IMSA101</classLabel>
<deletedAxiom>&apos;STING Agonist IMSA101&apos; SubClassOf &apos;Antineoplastic Immunomodulating Agent&apos;</deletedAxiom>
<newAxiom>&apos;STING Agonist IMSA101&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176586</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126151</classIRI>
<classLabel>Putting on Shoes, Stockings, or Socks Without Rest or a Break</classLabel>
<deletedAxiom>&apos;Putting on Shoes, Stockings, or Socks Without Rest or a Break&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Putting on Shoes, Stockings, or Socks Without Rest or a Break&apos; SubClassOf &apos;Dressing Ability&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126160</classIRI>
<classLabel>Putting Groceries on Shelves</classLabel>
<deletedAxiom>&apos;Putting Groceries on Shelves&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Putting Groceries on Shelves&apos; SubClassOf &apos;Play or Do Physical Activity Question&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165737</classIRI>
<classLabel>Locally Recurrent Skin Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Locally Recurrent Skin Squamous Cell Carcinoma&apos; EquivalentTo &apos;Recurrent Skin Squamous Cell Carcinoma&apos; and &apos;Localized Carcinoma&apos; and &apos;Locally Recurrent Malignant Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Locally Recurrent Skin Squamous Cell Carcinoma&apos; EquivalentTo &apos;Recurrent Skin Squamous Cell Carcinoma&apos; and &apos;Locally Recurrent Malignant Neoplasm&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165740</classIRI>
<classLabel>Locally Recurrent Merkel Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Locally Recurrent Merkel Cell Carcinoma&apos; EquivalentTo &apos;Recurrent Merkel Cell Carcinoma&apos; and &apos;Localized Carcinoma&apos; and &apos;Locally Recurrent Malignant Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Locally Recurrent Merkel Cell Carcinoma&apos; EquivalentTo &apos;Recurrent Merkel Cell Carcinoma&apos; and &apos;Locally Recurrent Malignant Neoplasm&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165748</classIRI>
<classLabel>STING Agonist GSK3745417</classLabel>
<deletedAxiom>&apos;STING Agonist GSK3745417&apos; SubClassOf &apos;Antineoplastic Immunomodulating Agent&apos;</deletedAxiom>
<newAxiom>&apos;STING Agonist GSK3745417&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176586</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126146</classIRI>
<classLabel>Getting Clothes from Drawers or Closets</classLabel>
<deletedAxiom>&apos;Getting Clothes from Drawers or Closets&apos; SubClassOf &apos;Ability Question&apos;</deletedAxiom>
<newAxiom>&apos;Getting Clothes from Drawers or Closets&apos; SubClassOf &apos;Dressing Ability&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126140</classIRI>
<classLabel>Reading Ability</classLabel>
<newAxiom>&apos;Reading Ability&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176426</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18249</classIRI>
<classLabel>CDH1 Gene</classLabel>
<newAxiom>&apos;CDH1 Gene&apos; SubClassOf &apos;Gene_Involved_In_Pathogenesis_Of_Disease&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176628</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165566</classIRI>
<classLabel>STING Agonist SB 11285</classLabel>
<deletedAxiom>&apos;STING Agonist SB 11285&apos; SubClassOf &apos;Antineoplastic Immunomodulating Agent&apos;</deletedAxiom>
<newAxiom>&apos;STING Agonist SB 11285&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176586</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5105</classIRI>
<classLabel>Colorectal Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Colorectal Adenocarcinoma&apos; EquivalentTo &apos;Adenocarcinoma&apos; and &apos;Colorectal Carcinoma&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Colorectal Adenocarcinoma&apos; EquivalentTo &apos;Adenocarcinoma&apos; and &apos;Colorectal Carcinoma&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131898</classIRI>
<classLabel>No Hearing Problems</classLabel>
<deletedAxiom>&apos;No Hearing Problems&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;No Hearing Problems&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176249</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18456</classIRI>
<classLabel>S-Phase Fraction</classLabel>
<deletedAxiom>&apos;S-Phase Fraction&apos; SubClassOf &apos;Property or Attribute&apos;</deletedAxiom>
<newAxiom>&apos;S-Phase Fraction&apos; SubClassOf &apos;Quantitative Concept&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5060</classIRI>
<classLabel>Non-Metastatic Fibrosarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Fibrosarcoma&apos; EquivalentTo &apos;Fibrosarcoma&apos; and &apos;Non-Metastatic Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Fibrosarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176558 and &apos;Fibrosarcoma&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5016</classIRI>
<classLabel>Stage I Rectosigmoid Cancer AJCC v6 and v7</classLabel>
<deletedAxiom>&apos;Stage I Rectosigmoid Cancer AJCC v6 and v7&apos; EquivalentTo &apos;Stage I Colorectal Cancer AJCC v6 and v7&apos; and &apos;Rectosigmoid Cancer by AJCC v6 Stage&apos; and &apos;Rectosigmoid Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;)</deletedAxiom>
<newAxiom>&apos;Stage I Rectosigmoid Cancer AJCC v6 and v7&apos; EquivalentTo &apos;Stage I Colorectal Cancer AJCC v6 and v7&apos; and &apos;Rectosigmoid Cancer by AJCC v6 Stage&apos; and &apos;Rectosigmoid Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C5015</classIRI>
<classLabel>Stage II Rectosigmoid Cancer AJCC v6</classLabel>
<deletedAxiom>&apos;Stage II Rectosigmoid Cancer AJCC v6&apos; EquivalentTo &apos;Stage II Colorectal Cancer AJCC v6&apos; and &apos;Rectosigmoid Cancer by AJCC v6 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;)</deletedAxiom>
<newAxiom>&apos;Stage II Rectosigmoid Cancer AJCC v6&apos; EquivalentTo &apos;Stage II Colorectal Cancer AJCC v6&apos; and &apos;Rectosigmoid Cancer by AJCC v6 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131922</classIRI>
<classLabel>Mobility Ability</classLabel>
<deletedAxiom>&apos;Mobility Ability&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Mobility Ability&apos; SubClassOf &apos;Play or Do Physical Activity Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43538</classIRI>
<classLabel>Small Intestinal Undifferentiated Carcinoma</classLabel>
<deletedAxiom>&apos;Small Intestinal Undifferentiated Carcinoma&apos; EquivalentTo &apos;Undifferentiated Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Small Intestinal Undifferentiated Carcinoma&apos; EquivalentTo &apos;Undifferentiated Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43537</classIRI>
<classLabel>Small Intestinal Medullary Carcinoma</classLabel>
<deletedAxiom>&apos;Small Intestinal Medullary Carcinoma&apos; EquivalentTo &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Epithelial Cell with Vesicular Nucleus, Distinct Nucleolus, and Abundant Pink Cytoplasm&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Small Intestinal Medullary Carcinoma&apos; EquivalentTo &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Epithelial Cell with Vesicular Nucleus, Distinct Nucleolus, and Abundant Pink Cytoplasm&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43534</classIRI>
<classLabel>Small Intestinal Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Small Intestinal Squamous Cell Carcinoma&apos; EquivalentTo &apos;Squamous Cell Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Small Intestinal Squamous Cell Carcinoma&apos; EquivalentTo &apos;Squamous Cell Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43536</classIRI>
<classLabel>Small Intestinal Mucinous Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Small Intestinal Mucinous Adenocarcinoma&apos; EquivalentTo &apos;Mucinous Adenocarcinoma&apos; and &apos;Small Intestinal Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Mucoid Stroma Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Small Intestinal Mucinous Adenocarcinoma&apos; EquivalentTo &apos;Mucinous Adenocarcinoma&apos; and &apos;Small Intestinal Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Mucoid Stroma Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43535</classIRI>
<classLabel>Small Intestinal Adenosquamous Carcinoma</classLabel>
<deletedAxiom>&apos;Small Intestinal Adenosquamous Carcinoma&apos; EquivalentTo &apos;Adenosquamous Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Small Intestinal Adenosquamous Carcinoma&apos; EquivalentTo &apos;Adenosquamous Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43543</classIRI>
<classLabel>Small Intestinal Signet Ring Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Small Intestinal Signet Ring Cell Carcinoma&apos; EquivalentTo &apos;Signet Ring Cell Carcinoma&apos; and &apos;Small Intestinal Adenocarcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Small Intestinal Signet Ring Cell Carcinoma&apos; EquivalentTo &apos;Signet Ring Cell Carcinoma&apos; and &apos;Small Intestinal Adenocarcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131996</classIRI>
<classLabel>Did Not Hear Ringing or Other Noises</classLabel>
<deletedAxiom>&apos;Did Not Hear Ringing or Other Noises&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Did Not Hear Ringing or Other Noises&apos; SubClassOf &apos;Ringing or Other Noises Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131995</classIRI>
<classLabel>Hearing Problems Did Not Interfere with Activities</classLabel>
<deletedAxiom>&apos;Hearing Problems Did Not Interfere with Activities&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Hearing Problems Did Not Interfere with Activities&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176249</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131947</classIRI>
<classLabel>Mobily Independent, but May Require a Walking Aid</classLabel>
<newAxiom>&apos;Mobily Independent, but May Require a Walking Aid&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131946</classIRI>
<classLabel>Walks with Help of One Person</classLabel>
<newAxiom>&apos;Walks with Help of One Person&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131697</classIRI>
<classLabel>Have Darker or Lighter Skin than Normal</classLabel>
<newAxiom>&apos;Have Darker or Lighter Skin than Normal&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131699</classIRI>
<classLabel>Nails Look Unusual</classLabel>
<deletedAxiom>&apos;Nails Look Unusual&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Nails Look Unusual&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43591</classIRI>
<classLabel>Colorectal Undifferentiated Carcinoma</classLabel>
<deletedAxiom>&apos;Colorectal Undifferentiated Carcinoma&apos; EquivalentTo &apos;Colorectal Carcinoma&apos; and &apos;Undifferentiated Carcinoma&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Colorectal Undifferentiated Carcinoma&apos; EquivalentTo &apos;Colorectal Carcinoma&apos; and &apos;Undifferentiated Carcinoma&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43590</classIRI>
<classLabel>Colorectal Medullary Carcinoma</classLabel>
<deletedAxiom>&apos;Colorectal Medullary Carcinoma&apos; EquivalentTo &apos;Colorectal Adenocarcinoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Epithelial Cell with Vesicular Nucleus, Distinct Nucleolus, and Abundant Pink Cytoplasm&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Colorectal Medullary Carcinoma&apos; EquivalentTo &apos;Colorectal Adenocarcinoma&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Epithelial Cell with Vesicular Nucleus, Distinct Nucleolus, and Abundant Pink Cytoplasm&apos;) and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43585</classIRI>
<classLabel>Colorectal Mucinous Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Colorectal Mucinous Adenocarcinoma&apos; EquivalentTo &apos;Mucinous Adenocarcinoma&apos; and &apos;Colorectal Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Mucoid Stroma Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Colorectal Mucinous Adenocarcinoma&apos; EquivalentTo &apos;Mucinous Adenocarcinoma&apos; and &apos;Colorectal Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Mucoid Stroma Formation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43584</classIRI>
<classLabel>Rectosigmoid Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Rectosigmoid Adenocarcinoma&apos; EquivalentTo &apos;Colorectal Adenocarcinoma&apos; and &apos;Rectosigmoid Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;)</deletedAxiom>
<newAxiom>&apos;Rectosigmoid Adenocarcinoma&apos; EquivalentTo &apos;Colorectal Adenocarcinoma&apos; and &apos;Rectosigmoid Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43587</classIRI>
<classLabel>Colorectal Small Cell Neuroendocrine Carcinoma</classLabel>
<deletedAxiom>&apos;Colorectal Small Cell Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Digestive System Small Cell Neuroendocrine Carcinoma&apos; and &apos;Colorectal Neuroendocrine Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Colorectal Small Cell Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Digestive System Small Cell Neuroendocrine Carcinoma&apos; and &apos;Colorectal Neuroendocrine Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43586</classIRI>
<classLabel>Colorectal Signet Ring Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Colorectal Signet Ring Cell Carcinoma&apos; EquivalentTo &apos;Colorectal Poorly Cohesive Adenocarcinoma&apos; and &apos;Signet Ring Cell Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Colorectal Signet Ring Cell Carcinoma&apos; EquivalentTo &apos;Colorectal Poorly Cohesive Adenocarcinoma&apos; and &apos;Signet Ring Cell Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43589</classIRI>
<classLabel>Colorectal Adenosquamous Carcinoma</classLabel>
<deletedAxiom>&apos;Colorectal Adenosquamous Carcinoma&apos; EquivalentTo &apos;Colorectal Carcinoma&apos; and &apos;Adenosquamous Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Colorectal Adenosquamous Carcinoma&apos; EquivalentTo &apos;Colorectal Carcinoma&apos; and &apos;Adenosquamous Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43588</classIRI>
<classLabel>Colorectal Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Colorectal Squamous Cell Carcinoma&apos; EquivalentTo &apos;Squamous Cell Carcinoma&apos; and &apos;Colorectal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Colorectal Squamous Cell Carcinoma&apos; EquivalentTo &apos;Squamous Cell Carcinoma&apos; and &apos;Colorectal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C106684</classIRI>
<classLabel>Sitting and Reading</classLabel>
<newAxiom>&apos;Sitting and Reading&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176426</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C131736</classIRI>
<classLabel>Walking on Flat Ground</classLabel>
<deletedAxiom>&apos;Walking on Flat Ground&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Walking on Flat Ground&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168871</classIRI>
<classLabel>Karyotype Status</classLabel>
<deletedAxiom>&apos;Karyotype Status&apos; SubClassOf &apos;Medical Status&apos;</deletedAxiom>
<newAxiom>&apos;Karyotype Status&apos; SubClassOf &apos;Genetic Finding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C154242</classIRI>
<classLabel>Solve Problems with Health Care or Health Care System</classLabel>
<deletedAxiom>&apos;Solve Problems with Health Care or Health Care System&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Solve Problems with Health Care or Health Care System&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120570</classIRI>
<classLabel>Pentetate Zinc</classLabel>
<deletedAxiom>&apos;Pentetate Zinc&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Pentetate Zinc&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120569</classIRI>
<classLabel>Pentetate Calcium</classLabel>
<deletedAxiom>&apos;Pentetate Calcium&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Pentetate Calcium&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7888</classIRI>
<classLabel>Small Intestinal Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Small Intestinal Adenocarcinoma&apos; EquivalentTo &apos;Adenocarcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 5q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 18q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 17p&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Microsatellite Instability&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Loss of E-cadherin Expression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CTNNB1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;SMAD4 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KRAS Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Small Intestinal Adenocarcinoma&apos; EquivalentTo &apos;Adenocarcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_Has_Normal_Tissue_Origin&apos; some &apos;Glandular Epithelium&apos;) and (&apos;Disease_Has_Normal_Cell_Origin&apos; some &apos;Glandular Cell&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 5q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 18q&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Loss of Chromosome 17p&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Microsatellite Instability&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Loss of E-cadherin Expression&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;CTNNB1 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;SMAD4 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KRAS Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7894</classIRI>
<classLabel>Recurrent Small Intestinal Carcinoma</classLabel>
<deletedAxiom>&apos;Recurrent Small Intestinal Carcinoma&apos; EquivalentTo &apos;Recurrent Digestive System Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Recurrent Small Intestinal Carcinoma&apos; EquivalentTo &apos;Recurrent Digestive System Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7826</classIRI>
<classLabel>Localized Parathyroid Gland Carcinoma</classLabel>
<deletedAxiom>&apos;Localized Parathyroid Gland Carcinoma&apos; EquivalentTo &apos;Parathyroid Gland Carcinoma&apos; and &apos;Localized Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Localized Parathyroid Gland Carcinoma&apos; EquivalentTo &apos;Non-Metastatic Head and Neck Carcinoma&apos; and &apos;Parathyroid Gland Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Localized Ewing Sarcoma</classLabel>
<deletedAxiom>&apos;Localized Ewing Sarcoma&apos; EquivalentTo &apos;Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor&apos; and &apos;Ewing Sarcoma&apos;</deletedAxiom>
<newAxiom>&apos;Localized Ewing Sarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176558 and &apos;Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor&apos; and &apos;Ewing Sarcoma&apos;</newAxiom>
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<classLabel>Immunodeficiency with Hyper-IgM Type 2</classLabel>
<deletedAxiom>&apos;Immunodeficiency with Hyper-IgM Type 2&apos; SubClassOf &apos;Rare Non-Neoplastic Disorder&apos;</deletedAxiom>
<deletedAxiom>&apos;Immunodeficiency with Hyper-IgM Type 2&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;AICDA Gene&apos;</deletedAxiom>
<newAxiom>&apos;Immunodeficiency with Hyper-IgM Type 2&apos; EquivalentTo &apos;Immunodeficiency With Hyper-IgM&apos; and (&apos;Disease_Mapped_To_Gene&apos; some &apos;AICDA Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120626</classIRI>
<classLabel>Anti-Neutrophil Cytoplasmic Antibody Measurement</classLabel>
<deletedAxiom>&apos;Anti-Neutrophil Cytoplasmic Antibody Measurement&apos; SubClassOf &apos;Immunology Test&apos;</deletedAxiom>
<newAxiom>&apos;Anti-Neutrophil Cytoplasmic Antibody Measurement&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176313</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C134934</classIRI>
<classLabel>Difficulty Remembering What is Read</classLabel>
<newAxiom>&apos;Difficulty Remembering What is Read&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176426</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C134935</classIRI>
<classLabel>Feel Not Good Looking</classLabel>
<newAxiom>&apos;Feel Not Good Looking&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77835</classIRI>
<classLabel>Pentetate Zinc Trisodium</classLabel>
<deletedAxiom>&apos;Pentetate Zinc Trisodium&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Pentetate Zinc Trisodium&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Severe Problems Walking</classLabel>
<deletedAxiom>&apos;Severe Problems Walking&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Severe Problems Walking&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Slight Problems Walking</classLabel>
<deletedAxiom>&apos;Slight Problems Walking&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Slight Problems Walking&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Moderate Problems Walking</classLabel>
<deletedAxiom>&apos;Moderate Problems Walking&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Moderate Problems Walking&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Unable to Walk</classLabel>
<newAxiom>&apos;Unable to Walk&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Washing or Dressing Self-Care Today</classLabel>
<deletedAxiom>&apos;Washing or Dressing Self-Care Today&apos; SubClassOf &apos;Play or Do Physical Activity Question&apos;</deletedAxiom>
<newAxiom>&apos;Washing or Dressing Self-Care Today&apos; SubClassOf &apos;Dressing Ability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120246</classIRI>
<classLabel>A Lot of Problems Walking</classLabel>
<deletedAxiom>&apos;A Lot of Problems Walking&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;A Lot of Problems Walking&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Isopentane</classLabel>
<deletedAxiom>&apos;Isopentane&apos; SubClassOf &apos;Organic Chemical&apos;</deletedAxiom>
<newAxiom>&apos;Isopentane&apos; SubClassOf &apos;Hydrocarbon&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>CA125 II Assay</classLabel>
<deletedAxiom>&apos;CA125 II Assay&apos; SubClassOf &apos;Immunology Test&apos;</deletedAxiom>
<newAxiom>&apos;CA125 II Assay&apos; SubClassOf &apos;CA-125 Measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63637</classIRI>
<classLabel>RNA Integrity Number</classLabel>
<deletedAxiom>&apos;RNA Integrity Number&apos; SubClassOf &apos;Property or Attribute&apos;</deletedAxiom>
<newAxiom>&apos;RNA Integrity Number&apos; SubClassOf &apos;Quantitative Concept&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173421</classIRI>
<classLabel>Anti-CD47 ADC SGN-CD47M</classLabel>
<deletedAxiom>&apos;Anti-CD47 ADC SGN-CD47M&apos; SubClassOf &apos;Anti-CD30 Antibody-drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD47 ADC SGN-CD47M&apos; SubClassOf &apos;Antineoplastic Antibody-Drug Conjugate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173420</classIRI>
<classLabel>Anti-HER2-DM1 ADC B003</classLabel>
<deletedAxiom>&apos;Anti-HER2-DM1 ADC B003&apos; SubClassOf &apos;Anti-CD30 Antibody-drug Conjugate&apos;</deletedAxiom>
<newAxiom>&apos;Anti-HER2-DM1 ADC B003&apos; SubClassOf &apos;Anti-HER2 Antibody-drug Conjugate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148446</classIRI>
<classLabel>Have Problems Learning About Medical Condition Due to Difficulty Understanding Written Information</classLabel>
<newAxiom>&apos;Have Problems Learning About Medical Condition Due to Difficulty Understanding Written Information&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148473</classIRI>
<classLabel>My Questions Were Answered to My Satisfaction</classLabel>
<deletedAxiom>&apos;My Questions Were Answered to My Satisfaction&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;My Questions Were Answered to My Satisfaction&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148442</classIRI>
<classLabel>Require Help to Read Hospital Materials</classLabel>
<deletedAxiom>&apos;Require Help to Read Hospital Materials&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Require Help to Read Hospital Materials&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176426</newAxiom>
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<changedClass>
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<classLabel>This Doctor Always Follows Up on My Visits to Other Health Care Providers</classLabel>
<newAxiom>&apos;This Doctor Always Follows Up on My Visits to Other Health Care Providers&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
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<classLabel>I Wonder if This Doctor is Cutting Corners on My Health Care</classLabel>
<newAxiom>&apos;I Wonder if This Doctor is Cutting Corners on My Health Care&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148585</classIRI>
<classLabel>My Medical Care Improves When I See the Same Doctor that I Have Seen Before</classLabel>
<newAxiom>&apos;My Medical Care Improves When I See the Same Doctor that I Have Seen Before&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173541</classIRI>
<classLabel>Anti-TRAILR2/CDH17 Tetravalent Bispecific Antibody BI 905711</classLabel>
<deletedAxiom>&apos;Anti-TRAILR2/CDH17 Tetravalent Bispecific Antibody BI 905711&apos; SubClassOf &apos;Anti-CTLA-4 Monoclonal Antibody&apos;</deletedAxiom>
<deletedAxiom>&apos;Anti-TRAILR2/CDH17 Tetravalent Bispecific Antibody BI 905711&apos; SubClassOf &apos;Anti-PD1 Monoclonal Antibody&apos;</deletedAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173529</classIRI>
<classLabel>Inotropic Agent</classLabel>
<deletedAxiom>&apos;Inotropic Agent&apos; SubClassOf &apos;Agent&apos;</deletedAxiom>
<newAxiom>&apos;Inotropic Agent&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148593</classIRI>
<classLabel>This Doctor Keeps Track of All My Health Care</classLabel>
<newAxiom>&apos;This Doctor Keeps Track of All My Health Care&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148592</classIRI>
<classLabel>I Want One Doctor to Coordinate All of the Health Care I Receive</classLabel>
<newAxiom>&apos;I Want One Doctor to Coordinate All of the Health Care I Receive&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148598</classIRI>
<classLabel>This Doctor Takes Responsibility for Helping Me Get All the Health Care I Need</classLabel>
<newAxiom>&apos;This Doctor Takes Responsibility for Helping Me Get All the Health Care I Need&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148588</classIRI>
<classLabel>I Rarely See the Same Doctor When I Go for Medical Care</classLabel>
<newAxiom>&apos;I Rarely See the Same Doctor When I Go for Medical Care&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173590</classIRI>
<classLabel>Macrometastasis Greater than 2.0 mm</classLabel>
<deletedAxiom>&apos;Macrometastasis Greater than 2.0 mm&apos; SubClassOf &apos;Morphologic Finding&apos;</deletedAxiom>
<newAxiom>&apos;Macrometastasis Greater than 2.0 mm&apos; SubClassOf &apos;Micrometastasis&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101613</classIRI>
<classLabel>Sharpin</classLabel>
<deletedAxiom>&apos;Sharpin&apos; EquivalentTo &apos;Ubiquitination Regulation Protein&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cytosol&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immunoregulation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Polyubiquitination&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Tumor Necrosis Factor Signaling Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;SHARPIN Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Sharpin&apos; EquivalentTo &apos;Ubiquitination Regulation Protein&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cytosol&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176221) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immunoregulation&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Polyubiquitination&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Tumor Necrosis Factor Signaling Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;SHARPIN Gene&apos;)</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83119</classIRI>
<classLabel>Physical Exam Result</classLabel>
<newAxiom>&apos;Physical Exam Result&apos; SubClassOf &apos;Clinical Test Result&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C140938</classIRI>
<classLabel>Satisfaction with How Natural Your Reconstructed Breasts Look</classLabel>
<newAxiom>&apos;Satisfaction with How Natural Your Reconstructed Breasts Look&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115997</classIRI>
<classLabel>Localized Adult Undifferentiated High Grade Pleomorphic Sarcoma of Bone</classLabel>
<deletedAxiom>&apos;Localized Adult Undifferentiated High Grade Pleomorphic Sarcoma of Bone&apos; EquivalentTo &apos;Adult Undifferentiated High Grade Pleomorphic Sarcoma of Bone&apos; and &apos;Localized Malignant Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Localized Adult Undifferentiated High Grade Pleomorphic Sarcoma of Bone&apos; EquivalentTo &apos;Adult Undifferentiated High Grade Pleomorphic Sarcoma of Bone&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176558</newAxiom>
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<classLabel>Localized Childhood Undifferentiated High Grade Pleomorphic Sarcoma of Bone</classLabel>
<deletedAxiom>&apos;Localized Childhood Undifferentiated High Grade Pleomorphic Sarcoma of Bone&apos; EquivalentTo &apos;Childhood Undifferentiated High Grade Pleomorphic Sarcoma of Bone&apos; and &apos;Localized Malignant Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Localized Childhood Undifferentiated High Grade Pleomorphic Sarcoma of Bone&apos; EquivalentTo &apos;Childhood Undifferentiated High Grade Pleomorphic Sarcoma of Bone&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176558</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C140954</classIRI>
<classLabel>Satisfaction with Appearance of Abdominal Scars</classLabel>
<newAxiom>&apos;Satisfaction with Appearance of Abdominal Scars&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C140952</classIRI>
<classLabel>Satisfaction with How Your Abdomen Looks When Unclothed</classLabel>
<newAxiom>&apos;Satisfaction with How Your Abdomen Looks When Unclothed&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C140738</classIRI>
<classLabel>Satisfaction with How You Look in Mirror Unclothed</classLabel>
<newAxiom>&apos;Satisfaction with How You Look in Mirror Unclothed&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C140735</classIRI>
<classLabel>Satisfaction with How You Look in Mirror Clothed</classLabel>
<newAxiom>&apos;Satisfaction with How You Look in Mirror Clothed&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115796</classIRI>
<classLabel>Disability Rating Scale Questionnaire</classLabel>
<deletedAxiom>&apos;Disability Rating Scale Questionnaire&apos; SubClassOf &apos;Clinical or Research Assessment Questionnaire&apos;</deletedAxiom>
<newAxiom>&apos;Disability Rating Scale Questionnaire&apos; SubClassOf &apos;Clinical Classification&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115770</classIRI>
<classLabel>Wishes About Care if Dying</classLabel>
<deletedAxiom>&apos;Wishes About Care if Dying&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Wishes About Care if Dying&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174214</classIRI>
<classLabel>Every Time</classLabel>
<deletedAxiom>&apos;Every Time&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Every Time&apos; SubClassOf &apos;Time Frequency Answer&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8576</classIRI>
<classLabel>Localized Malignant Neoplasm</classLabel>
<deletedAxiom>&apos;Localized Malignant Neoplasm&apos; EquivalentTo &apos;Malignant Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Localized Disease&apos;)</deletedAxiom>
<newAxiom>&apos;Localized Malignant Neoplasm&apos; EquivalentTo &apos;Non-Metastatic Neoplasm&apos; and &apos;Malignant Neoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115380</classIRI>
<classLabel>Recurrent Childhood Subependymal Giant Cell Astrocytoma</classLabel>
<deletedAxiom>&apos;Recurrent Childhood Subependymal Giant Cell Astrocytoma&apos; EquivalentTo &apos;Childhood Subependymal Giant Cell Astrocytoma&apos; and &apos;Recurrent Childhood Astrocytic Tumor&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Childhood Subependymal Giant Cell Astrocytoma&apos; EquivalentTo &apos;Childhood Subependymal Giant Cell Astrocytoma&apos; and &apos;Recurrent Childhood Astrocytic Tumor&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176464</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129982</classIRI>
<classLabel>Spinocerebellar Ataxia Type 1</classLabel>
<newAxiom>&apos;Spinocerebellar Ataxia Type 1&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176696</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115342</classIRI>
<classLabel>Concerned About Thinness of Appearance</classLabel>
<newAxiom>&apos;Concerned About Thinness of Appearance&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8514</classIRI>
<classLabel>Stage II Colorectal Cancer AJCC v6</classLabel>
<deletedAxiom>&apos;Stage II Colorectal Cancer AJCC v6&apos; EquivalentTo &apos;Colorectal Cancer by AJCC v6 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage II&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;)</deletedAxiom>
<newAxiom>&apos;Stage II Colorectal Cancer AJCC v6&apos; EquivalentTo &apos;Colorectal Cancer by AJCC v6 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage II&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8515</classIRI>
<classLabel>Stage III Colorectal Cancer AJCC v6</classLabel>
<deletedAxiom>&apos;Stage III Colorectal Cancer AJCC v6&apos; EquivalentTo &apos;Colorectal Cancer by AJCC v6 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage III&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;)</deletedAxiom>
<newAxiom>&apos;Stage III Colorectal Cancer AJCC v6&apos; EquivalentTo &apos;Colorectal Cancer by AJCC v6 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage III&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115372</classIRI>
<classLabel>Recurrent Childhood Pilocytic Astrocytoma</classLabel>
<deletedAxiom>&apos;Recurrent Childhood Pilocytic Astrocytoma&apos; EquivalentTo &apos;Recurrent Childhood Astrocytic Tumor&apos; and &apos;Childhood Pilocytic Astrocytoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Childhood Pilocytic Astrocytoma&apos; EquivalentTo &apos;Recurrent Childhood Astrocytic Tumor&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176464 and &apos;Childhood Pilocytic Astrocytoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8513</classIRI>
<classLabel>Stage I Colorectal Cancer AJCC v6 and v7</classLabel>
<deletedAxiom>&apos;Stage I Colorectal Cancer AJCC v6 and v7&apos; EquivalentTo &apos;Colorectal Cancer by AJCC v6 Stage&apos; and &apos;Colorectal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage I&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;)</deletedAxiom>
<newAxiom>&apos;Stage I Colorectal Cancer AJCC v6 and v7&apos; EquivalentTo &apos;Colorectal Cancer by AJCC v6 Stage&apos; and &apos;Colorectal Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;) and (&apos;Disease_Is_Stage&apos; some &apos;Stage I&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115447</classIRI>
<classLabel>Preference for Details of Information About Diagnosis and Treatment</classLabel>
<newAxiom>&apos;Preference for Details of Information About Diagnosis and Treatment&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115448</classIRI>
<classLabel>Rating of the Quality of Information from Oncologist About Treatment Choices</classLabel>
<newAxiom>&apos;Rating of the Quality of Information from Oncologist About Treatment Choices&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115454</classIRI>
<classLabel>Quality of the Information Received About Cancer Prognosis</classLabel>
<deletedAxiom>&apos;Quality of the Information Received About Cancer Prognosis&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Quality of the Information Received About Cancer Prognosis&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115453</classIRI>
<classLabel>Feelings About the Amount of Information Known About Cancer Prognosis</classLabel>
<newAxiom>&apos;Feelings About the Amount of Information Known About Cancer Prognosis&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8493</classIRI>
<classLabel>Hereditary Breast and Ovarian Cancer Syndrome</classLabel>
<deletedAxiom>&apos;Hereditary Breast and Ovarian Cancer Syndrome&apos; EquivalentTo &apos;Hereditary Neoplastic Syndrome&apos; and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Female Breast Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ovarian Carcinoma&apos;)</deletedAxiom>
<newAxiom>&apos;Hereditary Breast and Ovarian Cancer Syndrome&apos; EquivalentTo &apos;Hereditary Neoplastic Syndrome&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Deleterious BRCA Gene Mutation&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Female Breast Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ovarian Carcinoma&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8494</classIRI>
<classLabel>Lynch Syndrome</classLabel>
<deletedAxiom>&apos;Lynch Syndrome&apos; EquivalentTo &apos;Hereditary Nonpolyposis Colorectal Cancer Syndrome&apos; and &apos;DNA Repair Disorder&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ovarian Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Renal Pelvis Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Endometrial Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Small Intestinal Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ureter Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Gastric Intestinal-Type Adenocarcinoma&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;PMS1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;PMS2 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MSH6 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Inactivating MSH6 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PMS1 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Inactivating PMS2 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Lynch Syndrome&apos; EquivalentTo &apos;Hereditary Nonpolyposis Colorectal Cancer Syndrome&apos; and &apos;DNA Repair Disorder&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ovarian Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Renal Pelvis Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Endometrial Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Small Intestinal Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Ureter Carcinoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Gastric Intestinal-Type Adenocarcinoma&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;PMS1 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;PMS2 Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;MSH6 Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;High-Frequency Microsatellite Instability&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Inactivating MSH6 Gene Mutation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;PMS1 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;Inactivating PMS2 Gene Mutation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115401</classIRI>
<classLabel>CDISC Questionnaire DRS Test Name Terminology</classLabel>
<deletedAxiom>&apos;CDISC Questionnaire DRS Test Name Terminology&apos; SubClassOf &apos;CDISC Questionnaire Terminology&apos;</deletedAxiom>
<newAxiom>&apos;CDISC Questionnaire DRS Test Name Terminology&apos; SubClassOf &apos;CDISC Clinical Classification Terminology&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115402</classIRI>
<classLabel>CDISC Questionnaire DRS Test Code Terminology</classLabel>
<deletedAxiom>&apos;CDISC Questionnaire DRS Test Code Terminology&apos; SubClassOf &apos;CDISC Questionnaire Terminology&apos;</deletedAxiom>
<newAxiom>&apos;CDISC Questionnaire DRS Test Code Terminology&apos; SubClassOf &apos;CDISC Clinical Classification Terminology&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129765</classIRI>
<classLabel>Telomere Length</classLabel>
<deletedAxiom>&apos;Telomere Length&apos; SubClassOf &apos;Physical Property&apos;</deletedAxiom>
<newAxiom>&apos;Telomere Length&apos; SubClassOf &apos;Quantitative Concept&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115276</classIRI>
<classLabel>Have Difficulty Saying Some Words But Can Be Understood Over the Phone</classLabel>
<deletedAxiom>&apos;Have Difficulty Saying Some Words But Can Be Understood Over the Phone&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Have Difficulty Saying Some Words But Can Be Understood Over the Phone&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115285</classIRI>
<classLabel>Pain or Weakness in Shoulder has Caused Work Change</classLabel>
<deletedAxiom>&apos;Pain or Weakness in Shoulder has Caused Work Change&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Pain or Weakness in Shoulder has Caused Work Change&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115292</classIRI>
<classLabel>Non-Metastatic Childhood Soft Tissue Sarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Childhood Soft Tissue Sarcoma&apos; EquivalentTo &apos;Non-Metastatic Neoplasm&apos; and &apos;Childhood Soft Tissue Sarcoma&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Childhood Soft Tissue Sarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176558 and &apos;Childhood Soft Tissue Sarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115232</classIRI>
<classLabel>Have Severe Pain Controlled Only By Narcotics</classLabel>
<deletedAxiom>&apos;Have Severe Pain Controlled Only By Narcotics&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Have Severe Pain Controlled Only By Narcotics&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115233</classIRI>
<classLabel>Have Severe Pain Not Controlled By Medication</classLabel>
<deletedAxiom>&apos;Have Severe Pain Not Controlled By Medication&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Have Severe Pain Not Controlled By Medication&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115230</classIRI>
<classLabel>Mild Pain Not Needing Medication</classLabel>
<deletedAxiom>&apos;Mild Pain Not Needing Medication&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Mild Pain Not Needing Medication&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C115231</classIRI>
<classLabel>Have Moderate Pain that Requires Medication</classLabel>
<deletedAxiom>&apos;Have Moderate Pain that Requires Medication&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Have Moderate Pain that Requires Medication&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78197</classIRI>
<classLabel>Autologous Anti-PSMA Gene-Modified T-Lymphocytes</classLabel>
<deletedAxiom>&apos;Autologous Anti-PSMA Gene-Modified T-Lymphocytes&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168966</classIRI>
<classLabel>Inotropic Support</classLabel>
<deletedAxiom>&apos;Inotropic Support&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Inotropic Support&apos; SubClassOf &apos;Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8809</classIRI>
<classLabel>Non-Metastatic Extraskeletal Osteosarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Extraskeletal Osteosarcoma&apos; EquivalentTo &apos;Non-Metastatic Neoplasm&apos; and &apos;Extraskeletal Osteosarcoma&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Extraskeletal Osteosarcoma&apos; EquivalentTo &apos;Localized Osteosarcoma&apos; and &apos;Extraskeletal Osteosarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8802</classIRI>
<classLabel>Non-Metastatic Extraskeletal Ewing Sarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Extraskeletal Ewing Sarcoma&apos; EquivalentTo &apos;Non-Metastatic Neoplasm&apos; and &apos;Extraskeletal Ewing Sarcoma&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Extraskeletal Ewing Sarcoma&apos; EquivalentTo &apos;Extraskeletal Ewing Sarcoma&apos; and &apos;Localized Ewing Sarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8800</classIRI>
<classLabel>Non-Metastatic Epithelioid Sarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Epithelioid Sarcoma&apos; EquivalentTo &apos;Non-Metastatic Neoplasm&apos; and &apos;Epithelioid Sarcoma&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Epithelioid Sarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176558 and &apos;Epithelioid Sarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129350</classIRI>
<classLabel>Never or Almost Never</classLabel>
<deletedAxiom>&apos;Never or Almost Never&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Never or Almost Never&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176245</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8826</classIRI>
<classLabel>Non-Metastatic Synovial Sarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Synovial Sarcoma&apos; EquivalentTo &apos;Synovial Sarcoma&apos; and &apos;Non-Metastatic Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Synovial Sarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176558 and &apos;Synovial Sarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8817</classIRI>
<classLabel>Non-Metastatic Liposarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Liposarcoma&apos; EquivalentTo &apos;Liposarcoma&apos; and &apos;Non-Metastatic Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Liposarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176558 and &apos;Liposarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8814</classIRI>
<classLabel>Non-Metastatic Leiomyosarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Leiomyosarcoma&apos; EquivalentTo &apos;Leiomyosarcoma&apos; and &apos;Non-Metastatic Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Leiomyosarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176558 and &apos;Leiomyosarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78257</classIRI>
<classLabel>Duodenal Hemorrhage</classLabel>
<deletedAxiom>&apos;Duodenal Hemorrhage&apos; SubClassOf &apos;Intestinal Hemorrhage&apos;</deletedAxiom>
<newAxiom>&apos;Duodenal Hemorrhage&apos; SubClassOf &apos;Lower Gastrointestinal Hemorrhage&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78234</classIRI>
<classLabel>Cecal Hemorrhage</classLabel>
<deletedAxiom>&apos;Cecal Hemorrhage&apos; SubClassOf &apos;Intestinal Hemorrhage&apos;</deletedAxiom>
<newAxiom>&apos;Cecal Hemorrhage&apos; SubClassOf &apos;Lower Gastrointestinal Hemorrhage&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78240</classIRI>
<classLabel>Colonic Hemorrhage</classLabel>
<deletedAxiom>&apos;Colonic Hemorrhage&apos; SubClassOf &apos;Intestinal Hemorrhage&apos;</deletedAxiom>
<newAxiom>&apos;Colonic Hemorrhage&apos; SubClassOf &apos;Lower Gastrointestinal Hemorrhage&apos;</newAxiom>
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<classLabel>Extremely Dissatisfied</classLabel>
<deletedAxiom>&apos;Extremely Dissatisfied&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Extremely Dissatisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
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<changedClass>
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<classLabel>Extremely Satisfied</classLabel>
<deletedAxiom>&apos;Extremely Satisfied&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Extremely Satisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
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<changedClass>
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<deletedAxiom>&apos;Somewhat Dissatisfied&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Somewhat Dissatisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
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<changedClass>
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<newAxiom>&apos;Somewhat Satisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
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<changedClass>
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<newAxiom>&apos;Neither Satisfied nor Dissatisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
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<changedClass>
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<classLabel>Non-Metastatic Alveolar Soft Part Sarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Alveolar Soft Part Sarcoma&apos; EquivalentTo &apos;Non-Metastatic Neoplasm&apos; and &apos;Alveolar Soft Part Sarcoma&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Alveolar Soft Part Sarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176558 and &apos;Alveolar Soft Part Sarcoma&apos;</newAxiom>
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<changedClass>
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<classLabel>Jejunal Hemorrhage</classLabel>
<deletedAxiom>&apos;Jejunal Hemorrhage&apos; SubClassOf &apos;Intestinal Hemorrhage&apos;</deletedAxiom>
<newAxiom>&apos;Jejunal Hemorrhage&apos; SubClassOf &apos;Lower Gastrointestinal Hemorrhage&apos;</newAxiom>
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<classLabel>No Sexual Activity</classLabel>
<deletedAxiom>&apos;No Sexual Activity&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;No Sexual Activity&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176252</newAxiom>
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<classLabel>Very Satisfied</classLabel>
<deletedAxiom>&apos;Very Satisfied&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Very Satisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
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<changedClass>
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<classLabel>Moderately Satisfied</classLabel>
<deletedAxiom>&apos;Moderately Satisfied&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Moderately Satisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
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<changedClass>
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<classLabel>Slightly Difficult</classLabel>
<deletedAxiom>&apos;Slightly Difficult&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Slightly Difficult&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
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<classLabel>Not Difficult</classLabel>
<deletedAxiom>&apos;Not Difficult&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Not Difficult&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
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<deletedAxiom>&apos;Very Difficult&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Very Difficult&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
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<classLabel>Difficult</classLabel>
<deletedAxiom>&apos;Difficult&apos; SubClassOf &apos;Very Difficult&apos;</deletedAxiom>
<newAxiom>&apos;Difficult&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
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<classLabel>Extremely Difficult or Impossible</classLabel>
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<newAxiom>&apos;Extremely Difficult or Impossible&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
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<deletedAxiom>&apos;Moderately Dissatisfied&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Moderately Dissatisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
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<newAxiom>&apos;Very Dissatisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
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<changedClass>
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<classLabel>About Equally Satisfied and Dissatisfied</classLabel>
<deletedAxiom>&apos;About Equally Satisfied and Dissatisfied&apos; SubClassOf &apos;Moderately Satisfied&apos;</deletedAxiom>
<newAxiom>&apos;About Equally Satisfied and Dissatisfied&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78371</classIRI>
<classLabel>Intestinal Stoma Site Hemorrhage</classLabel>
<deletedAxiom>&apos;Intestinal Stoma Site Hemorrhage&apos; SubClassOf &apos;Intestinal Hemorrhage&apos;</deletedAxiom>
<newAxiom>&apos;Intestinal Stoma Site Hemorrhage&apos; SubClassOf &apos;Lower Gastrointestinal Hemorrhage&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78353</classIRI>
<classLabel>Ileal Hemorrhage</classLabel>
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<newAxiom>&apos;Ileal Hemorrhage&apos; SubClassOf &apos;Lower Gastrointestinal Hemorrhage&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8639</classIRI>
<classLabel>Resectable Small Intestinal Carcinoma</classLabel>
<deletedAxiom>&apos;Resectable Small Intestinal Carcinoma&apos; EquivalentTo &apos;Resectable Digestive System Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Resectable Small Intestinal Carcinoma&apos; EquivalentTo &apos;Resectable Digestive System Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8637</classIRI>
<classLabel>Metastatic Small Intestinal Carcinoma</classLabel>
<deletedAxiom>&apos;Metastatic Small Intestinal Carcinoma&apos; EquivalentTo &apos;Metastatic Digestive System Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Metastatic Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Metastatic Small Intestinal Carcinoma&apos; EquivalentTo &apos;Metastatic Digestive System Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176678 and &apos;Small Intestinal Carcinoma&apos;</newAxiom>
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<classLabel>Unresectable Small Intestinal Carcinoma</classLabel>
<deletedAxiom>&apos;Unresectable Small Intestinal Carcinoma&apos; EquivalentTo &apos;Unresectable Digestive System Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Unresectable Small Intestinal Carcinoma&apos; EquivalentTo &apos;Unresectable Digestive System Carcinoma&apos; and &apos;Small Intestinal Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8635</classIRI>
<classLabel>Stage III Rectosigmoid Cancer AJCC v6</classLabel>
<deletedAxiom>&apos;Stage III Rectosigmoid Cancer AJCC v6&apos; EquivalentTo &apos;Stage III Colorectal Cancer AJCC v6&apos; and &apos;Rectosigmoid Cancer by AJCC v6 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;)</deletedAxiom>
<newAxiom>&apos;Stage III Rectosigmoid Cancer AJCC v6&apos; EquivalentTo &apos;Stage III Colorectal Cancer AJCC v6&apos; and &apos;Rectosigmoid Cancer by AJCC v6 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8636</classIRI>
<classLabel>Stage IV Rectosigmoid Cancer AJCC v6</classLabel>
<deletedAxiom>&apos;Stage IV Rectosigmoid Cancer AJCC v6&apos; EquivalentTo &apos;Stage IV Colorectal Cancer AJCC v6&apos; and &apos;Rectosigmoid Cancer by AJCC v6 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;)</deletedAxiom>
<newAxiom>&apos;Stage IV Rectosigmoid Cancer AJCC v6&apos; EquivalentTo &apos;Stage IV Colorectal Cancer AJCC v6&apos; and &apos;Rectosigmoid Cancer by AJCC v6 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133870</classIRI>
<classLabel>Pharmaceutical Quality/CMC Validation Parameter Terminology</classLabel>
<deletedAxiom>&apos;Pharmaceutical Quality/CMC Validation Parameter Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;Pharmaceutical Quality/CMC Validation Parameter Terminology&apos; SubClassOf &apos;FDA Pharmaceutical Quality/CMC Terminology&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C6657</classIRI>
<classLabel>Ampulla of Vater Adenoma, Intestinal-Type</classLabel>
<deletedAxiom>&apos;Ampulla of Vater Adenoma, Intestinal-Type&apos; EquivalentTo &apos;Adenoma, Intestinal-Type&apos; and &apos;Digestive System Adenoma&apos; and &apos;Preinvasive Neoplasm of the Ampullary Region&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Ampulla of Vater&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Exophytic Polypoid Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Jaundice&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;APC Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;KRAS Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;APC Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KRAS Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;Ampulla of Vater Adenoma, Intestinal-Type&apos; EquivalentTo &apos;Adenoma, Intestinal-Type&apos; and &apos;Preinvasive Neoplasm of the Ampullary Region&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Ampulla of Vater&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Exophytic Polypoid Lesion&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Jaundice&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;APC Gene&apos;) and (&apos;Disease_Mapped_To_Gene&apos; some &apos;KRAS Gene&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;TP53 Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;APC Gene Inactivation&apos;) and (&apos;Disease_May_Have_Molecular_Abnormality&apos; some &apos;KRAS Gene Mutation&apos;)</newAxiom>
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<classLabel>Pharmaceutical Quality/CMC Chemical Structure Data File Type Terminology</classLabel>
<deletedAxiom>&apos;Pharmaceutical Quality/CMC Chemical Structure Data File Type Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;Pharmaceutical Quality/CMC Chemical Structure Data File Type Terminology&apos; SubClassOf &apos;FDA Pharmaceutical Quality/CMC Terminology&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133869</classIRI>
<classLabel>Pharmaceutical Quality/CMC Testing Site Unique Identifier Type Terminology</classLabel>
<deletedAxiom>&apos;Pharmaceutical Quality/CMC Testing Site Unique Identifier Type Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;Pharmaceutical Quality/CMC Testing Site Unique Identifier Type Terminology&apos; SubClassOf &apos;FDA Pharmaceutical Quality/CMC Terminology&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133860</classIRI>
<classLabel>Pharmaceutical Quality/CMC Quality Benchmark Terminology</classLabel>
<deletedAxiom>&apos;Pharmaceutical Quality/CMC Quality Benchmark Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;Pharmaceutical Quality/CMC Quality Benchmark Terminology&apos; SubClassOf &apos;FDA Pharmaceutical Quality/CMC Terminology&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133865</classIRI>
<classLabel>Pharmaceutical Quality/CMC Storage Conditions Terminology</classLabel>
<deletedAxiom>&apos;Pharmaceutical Quality/CMC Storage Conditions Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;Pharmaceutical Quality/CMC Storage Conditions Terminology&apos; SubClassOf &apos;FDA Pharmaceutical Quality/CMC Terminology&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133866</classIRI>
<classLabel>Pharmaceutical Quality/CMC Study Type Terminology</classLabel>
<deletedAxiom>&apos;Pharmaceutical Quality/CMC Study Type Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;Pharmaceutical Quality/CMC Study Type Terminology&apos; SubClassOf &apos;FDA Pharmaceutical Quality/CMC Terminology&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133857</classIRI>
<classLabel>Pharmaceutical Quality/CMC Interpretation Code (text) Terminology</classLabel>
<deletedAxiom>&apos;Pharmaceutical Quality/CMC Interpretation Code (text) Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;Pharmaceutical Quality/CMC Interpretation Code (text) Terminology&apos; SubClassOf &apos;FDA Pharmaceutical Quality/CMC Terminology&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C167270</classIRI>
<classLabel>STING-expressing E. coli SYNB1891</classLabel>
<deletedAxiom>&apos;STING-expressing E. coli SYNB1891&apos; SubClassOf &apos;Antineoplastic Immunomodulating Agent&apos;</deletedAxiom>
<newAxiom>&apos;STING-expressing E. coli SYNB1891&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176586</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C167193</classIRI>
<classLabel>PALB2-Mutated Breast Carcinoma</classLabel>
<deletedAxiom>&apos;PALB2-Mutated Breast Carcinoma&apos; EquivalentTo &apos;Hereditary Breast Carcinoma&apos; and (&apos;Disease_Has_Molecular_Abnormality&apos; some &apos;Deleterious PALB2 Gene Mutation&apos;)</deletedAxiom>
<newAxiom>&apos;PALB2-Mutated Breast Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176729 and &apos;Hereditary Breast Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C167316</classIRI>
<classLabel>Severe Difficulty</classLabel>
<deletedAxiom>&apos;Severe Difficulty&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Severe Difficulty&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C167314</classIRI>
<classLabel>Mild Difficulty</classLabel>
<deletedAxiom>&apos;Mild Difficulty&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Mild Difficulty&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C167315</classIRI>
<classLabel>Moderate Difficulty</classLabel>
<deletedAxiom>&apos;Moderate Difficulty&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Moderate Difficulty&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C167313</classIRI>
<classLabel>No Difficulty</classLabel>
<deletedAxiom>&apos;No Difficulty&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;No Difficulty&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C167323</classIRI>
<classLabel>So Much Difficulty Can&apos;t Sleep</classLabel>
<deletedAxiom>&apos;So Much Difficulty Can&apos;t Sleep&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;So Much Difficulty Can&apos;t Sleep&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
<newAxiom>&apos;So Much Difficulty Can&apos;t Sleep&apos; SubClassOf &apos;Sleep Responses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C167292</classIRI>
<classLabel>STING Agonist BMS-986301</classLabel>
<deletedAxiom>&apos;STING Agonist BMS-986301&apos; SubClassOf &apos;Antineoplastic Immunomodulating Agent&apos;</deletedAxiom>
<newAxiom>&apos;STING Agonist BMS-986301&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176586</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C167081</classIRI>
<classLabel>Recurrent Diffuse Astrocytoma</classLabel>
<deletedAxiom>&apos;Recurrent Diffuse Astrocytoma&apos; EquivalentTo &apos;Recurrent WHO Grade II Glioma&apos; and &apos;Diffuse Astrocytoma&apos;</deletedAxiom>
<newAxiom>&apos;Recurrent Diffuse Astrocytoma&apos; EquivalentTo &apos;Recurrent WHO Grade II Glioma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176464 and &apos;Diffuse Astrocytoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172780</classIRI>
<classLabel>Skin is Sensitive</classLabel>
<deletedAxiom>&apos;Skin is Sensitive&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Skin is Sensitive&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172784</classIRI>
<classLabel>Annoyed By Skin Condition</classLabel>
<deletedAxiom>&apos;Annoyed By Skin Condition&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Annoyed By Skin Condition&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172782</classIRI>
<classLabel>Humiliated by Skin Condition</classLabel>
<deletedAxiom>&apos;Humiliated by Skin Condition&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Humiliated by Skin Condition&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172785</classIRI>
<classLabel>Skin Condition Interferes with Sex Life</classLabel>
<newAxiom>&apos;Skin Condition Interferes with Sex Life&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176252</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172772</classIRI>
<classLabel>Water Bothers Skin Condition</classLabel>
<newAxiom>&apos;Water Bothers Skin Condition&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172770</classIRI>
<classLabel>Tend to Do Things Alone Because of Skin Condition</classLabel>
<deletedAxiom>&apos;Tend to Do Things Alone Because of Skin Condition&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Tend to Do Things Alone Because of Skin Condition&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172771</classIRI>
<classLabel>Angry About Skin Condition</classLabel>
<deletedAxiom>&apos;Angry About Skin Condition&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Angry About Skin Condition&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172777</classIRI>
<classLabel>Embarrassed by Skin Condition</classLabel>
<deletedAxiom>&apos;Embarrassed by Skin Condition&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Embarrassed by Skin Condition&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172775</classIRI>
<classLabel>Skin is Irritated</classLabel>
<deletedAxiom>&apos;Skin is Irritated&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Skin is Irritated&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172779</classIRI>
<classLabel>Frustrated By Skin Condition</classLabel>
<deletedAxiom>&apos;Frustrated By Skin Condition&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Frustrated By Skin Condition&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172765</classIRI>
<classLabel>Worry About Getting Scars from Skin Condition</classLabel>
<newAxiom>&apos;Worry About Getting Scars from Skin Condition&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172766</classIRI>
<classLabel>Skin Itches</classLabel>
<deletedAxiom>&apos;Skin Itches&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Skin Itches&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172764</classIRI>
<classLabel>Tend to Stay at Home Because of Skin Condition</classLabel>
<deletedAxiom>&apos;Tend to Stay at Home Because of Skin Condition&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Tend to Stay at Home Because of Skin Condition&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172769</classIRI>
<classLabel>Worry that Skin Condition May Get Worse</classLabel>
<newAxiom>&apos;Worry that Skin Condition May Get Worse&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172768</classIRI>
<classLabel>Ashamed of Skin Condition</classLabel>
<deletedAxiom>&apos;Ashamed of Skin Condition&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Ashamed of Skin Condition&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172759</classIRI>
<classLabel>Worry that Skin Condition May Be Serious</classLabel>
<newAxiom>&apos;Worry that Skin Condition May Be Serious&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172757</classIRI>
<classLabel>Skin Hurts</classLabel>
<deletedAxiom>&apos;Skin Hurts&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Skin Hurts&apos; SubClassOf &apos;Skin Condition Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39872</classIRI>
<classLabel>Urethral Villous Adenoma</classLabel>
<deletedAxiom>&apos;Urethral Villous Adenoma&apos; EquivalentTo &apos;Urethra Neoplasm&apos; and &apos;Villous Adenoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Urethra&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hematuria&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Rectal Tubulovillous Adenoma&apos;) and (&apos;Disease_May_Have_Associated_Disease&apos; some &apos;Rectal Adenocarcinoma&apos;)</deletedAxiom>
<newAxiom>&apos;Urethral Villous Adenoma&apos; EquivalentTo &apos;Adenoma&apos; and &apos;Benign Urethral Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Villous Pattern&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172933</classIRI>
<classLabel>Never Affects Sleep</classLabel>
<newAxiom>&apos;Never Affects Sleep&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176245</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25271</classIRI>
<classLabel>Painful</classLabel>
<deletedAxiom>&apos;Painful&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Painful&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25272</classIRI>
<classLabel>Painless</classLabel>
<deletedAxiom>&apos;Painless&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Painless&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172594</classIRI>
<classLabel>Hemofiltration</classLabel>
<newAxiom>&apos;Hemofiltration&apos; SubClassOf &apos;Blood Treatment&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172648</classIRI>
<classLabel>Unresectable Paranasal Sinus Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Unresectable Paranasal Sinus Squamous Cell Carcinoma&apos; EquivalentTo &apos;Unresectable Head and Neck Squamous Cell Carcinoma&apos; and &apos;Paranasal Sinus Squamous Cell Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Unresectable Paranasal Sinus Squamous Cell Carcinoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176513 and &apos;Paranasal Sinus Squamous Cell Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C50624</classIRI>
<classLabel>Irritation</classLabel>
<deletedAxiom>&apos;Irritation&apos; SubClassOf &apos;Other Finding&apos;</deletedAxiom>
<newAxiom>&apos;Irritation&apos; SubClassOf &apos;Inflammation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172498</classIRI>
<classLabel>Chenodeoxycholate Measurement</classLabel>
<deletedAxiom>&apos;Chenodeoxycholate Measurement&apos; SubClassOf &apos;Bile Acid Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Chenodeoxycholate Measurement&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176239</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C172499</classIRI>
<classLabel>Cholate Measurement</classLabel>
<deletedAxiom>&apos;Cholate Measurement&apos; SubClassOf &apos;Bile Acid Measurement&apos;</deletedAxiom>
<newAxiom>&apos;Cholate Measurement&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176232</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25953</classIRI>
<classLabel>Ribonuclease Gene</classLabel>
<deletedAxiom>&apos;Ribonuclease Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;RNA Degradation&apos;</deletedAxiom>
<newAxiom>&apos;Ribonuclease Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;RNA Processing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148315</classIRI>
<classLabel>Spinocerebellar Ataxia Type 2</classLabel>
<newAxiom>&apos;Spinocerebellar Ataxia Type 2&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176696</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148316</classIRI>
<classLabel>Spinocerebellar Ataxia Type 36</classLabel>
<newAxiom>&apos;Spinocerebellar Ataxia Type 36&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176696</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173377</classIRI>
<classLabel>STING Agonist TAK-676</classLabel>
<deletedAxiom>&apos;STING Agonist TAK-676&apos; SubClassOf &apos;Antineoplastic Immunomodulating Agent&apos;</deletedAxiom>
<newAxiom>&apos;STING Agonist TAK-676&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176586</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84539</classIRI>
<classLabel>Acyl-CoA Dehydrogenase, Short-Chain Deficiency</classLabel>
<newAxiom>&apos;Acyl-CoA Dehydrogenase, Short-Chain Deficiency&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;ACADS Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84562</classIRI>
<classLabel>Anhidrotic Ectodermal Dysplasia 1</classLabel>
<newAxiom>&apos;Anhidrotic Ectodermal Dysplasia 1&apos; SubClassOf &apos;Disease_Mapped_To_Gene&apos; some &apos;EDA Gene&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C148035</classIRI>
<classLabel>PSMA-Positive Tumor</classLabel>
<newAxiom>&apos;PSMA-Positive Tumor&apos; SubClassOf &apos;FOLH1 Positive&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C100173</classIRI>
<classLabel>CDISC Questionnaire SF36 v1.0 Standard Test Name Terminology</classLabel>
<deletedAxiom>&apos;CDISC Questionnaire SF36 v1.0 Standard Test Name Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;CDISC Questionnaire SF36 v1.0 Standard Test Name Terminology&apos; SubClassOf &apos;CDISC Questionnaire Terminology&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C100174</classIRI>
<classLabel>CDISC Questionnaire SF36 v1.0 Standard Test Code Terminology</classLabel>
<deletedAxiom>&apos;CDISC Questionnaire SF36 v1.0 Standard Test Code Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;CDISC Questionnaire SF36 v1.0 Standard Test Code Terminology&apos; SubClassOf &apos;CDISC Questionnaire Terminology&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84718</classIRI>
<classLabel>Friedreich Ataxia</classLabel>
<newAxiom>&apos;Friedreich Ataxia&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176696</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84717</classIRI>
<classLabel>Fragile X Syndrome</classLabel>
<newAxiom>&apos;Fragile X Syndrome&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176696</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84830</classIRI>
<classLabel>Spinocerebellar Ataxia Type 3</classLabel>
<newAxiom>&apos;Spinocerebellar Ataxia Type 3&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176696</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C114566</classIRI>
<classLabel>Phosphofurin Acidic Cluster Sorting Protein 1</classLabel>
<deletedAxiom>&apos;Phosphofurin Acidic Cluster Sorting Protein 1&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Membrane Protein Traffic&apos;</deletedAxiom>
<deletedAxiom>&apos;Phosphofurin Acidic Cluster Sorting Protein 1&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Golgi Targeting&apos;</deletedAxiom>
<deletedAxiom>&apos;Phosphofurin Acidic Cluster Sorting Protein 1&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Antiviral Response&apos;</deletedAxiom>
<deletedAxiom>&apos;Phosphofurin Acidic Cluster Sorting Protein 1&apos; SubClassOf &apos;Transport Protein&apos;</deletedAxiom>
<deletedAxiom>&apos;Phosphofurin Acidic Cluster Sorting Protein 1&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;PACS1 Gene&apos;</deletedAxiom>
<deletedAxiom>&apos;Phosphofurin Acidic Cluster Sorting Protein 1&apos; SubClassOf &apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Trans-Golgi Network&apos;</deletedAxiom>
<newAxiom>&apos;Phosphofurin Acidic Cluster Sorting Protein 1&apos; EquivalentTo &apos;Transport Protein&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Trans-Golgi Network&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Membrane Protein Traffic&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Golgi Targeting&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Antiviral Response&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;PACS1 Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84942</classIRI>
<classLabel>Oculopharyngeal Muscular Dystrophy</classLabel>
<newAxiom>&apos;Oculopharyngeal Muscular Dystrophy&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176696</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128922</classIRI>
<classLabel>High Resolution Anoscopy with Biopsy</classLabel>
<deletedAxiom>&apos;High Resolution Anoscopy with Biopsy&apos; SubClassOf &apos;Diagnostic Endoscopic Procedure&apos;</deletedAxiom>
<newAxiom>&apos;High Resolution Anoscopy with Biopsy&apos; SubClassOf &apos;Endoscopic Biopsy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45569</classIRI>
<classLabel>High Grade Lung Neuroendocrine Neoplasm</classLabel>
<deletedAxiom>&apos;High Grade Lung Neuroendocrine Neoplasm&apos; EquivalentTo &apos;Malignant Endocrine Neoplasm&apos; and &apos;Lung Neuroendocrine Neoplasm&apos; and &apos;Malignant Lung Neoplasm&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Neuroendocrine Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;High Grade Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;High Grade Lung Neuroendocrine Neoplasm&apos; EquivalentTo &apos;Neuroendocrine Carcinoma, Excluding Head and Neck&apos; and &apos;Lung Carcinoma&apos; and &apos;Lung Neuroendocrine Neoplasm&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Malignant Neuroendocrine Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;High Grade Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7173</classIRI>
<classLabel>Diffuse Astrocytoma</classLabel>
<deletedAxiom>&apos;Diffuse Astrocytoma&apos; EquivalentTo &apos;Diffuse Glioma&apos; and &apos;WHO Grade II Glioma&apos; and &apos;Astrocytoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Infiltrative Growth Pattern&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 2&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 7q&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Seizure&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Headache&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Calcification&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Motor Manifestations&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Sensory Manifestations&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Mitotic Activity&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Microvascular Proliferation&apos;)</deletedAxiom>
<newAxiom>&apos;Diffuse Astrocytoma&apos; EquivalentTo &apos;Low Grade Astrocytic Tumor&apos; and &apos;Diffuse Glioma&apos; and &apos;WHO Grade II Glioma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Infiltrative Growth Pattern&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 2&apos;) and (&apos;Disease_May_Have_Cytogenetic_Abnormality&apos; some &apos;Gain of Chromosome 7q&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Seizure&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Headache&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Calcification&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Motor Manifestations&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Sensory Manifestations&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Mitotic Activity&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Necrotic Change&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Microvascular Proliferation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153564</classIRI>
<classLabel>Preference for Making Decisions about Health Care</classLabel>
<newAxiom>&apos;Preference for Making Decisions about Health Care&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153537</classIRI>
<classLabel>Patients Generally Want Reassurance Rather than Information about Health</classLabel>
<deletedAxiom>&apos;Patients Generally Want Reassurance Rather than Information about Health&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Patients Generally Want Reassurance Rather than Information about Health&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153545</classIRI>
<classLabel>When Patients Look up Medical Information This Confuses More than Helps</classLabel>
<deletedAxiom>&apos;When Patients Look up Medical Information This Confuses More than Helps&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;When Patients Look up Medical Information This Confuses More than Helps&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153529</classIRI>
<classLabel>Health Care is Less Personal but Pays for Medical Advances</classLabel>
<deletedAxiom>&apos;Health Care is Less Personal but Pays for Medical Advances&apos; SubClassOf &apos;Clinical or Research Assessment Question&apos;</deletedAxiom>
<newAxiom>&apos;Health Care is Less Personal but Pays for Medical Advances&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7780</classIRI>
<classLabel>Localized Osteosarcoma</classLabel>
<deletedAxiom>&apos;Localized Osteosarcoma&apos; EquivalentTo &apos;Localized Malignant Neoplasm&apos; and &apos;Osteosarcoma&apos;</deletedAxiom>
<newAxiom>&apos;Localized Osteosarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176558 and &apos;Osteosarcoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7591</classIRI>
<classLabel>Combined Lung Carcinoma</classLabel>
<deletedAxiom>&apos;Combined Lung Carcinoma&apos; EquivalentTo &apos;Mixed Carcinoma&apos; and &apos;Neuroendocrine Carcinoma, Excluding Head and Neck&apos; and &apos;High Grade Lung Neuroendocrine Neoplasm&apos; and &apos;Lung Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Dyspnea&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemoptysis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cough&apos;)</deletedAxiom>
<newAxiom>&apos;Combined Lung Carcinoma&apos; EquivalentTo &apos;Mixed Carcinoma&apos; and &apos;High Grade Lung Neuroendocrine Neoplasm&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Dyspnea&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemoptysis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Cough&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7414</classIRI>
<classLabel>Bladder Villous Adenoma</classLabel>
<deletedAxiom>&apos;Bladder Villous Adenoma&apos; EquivalentTo &apos;Bladder Neoplasm&apos; and &apos;Villous Adenoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Bladder&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hematuria&apos;)</deletedAxiom>
<newAxiom>&apos;Bladder Villous Adenoma&apos; EquivalentTo &apos;Adenoma&apos; and &apos;Benign Bladder Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Villous Pattern&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90019</classIRI>
<classLabel>Stage IV Rectosigmoid Cancer AJCC v7</classLabel>
<deletedAxiom>&apos;Stage IV Rectosigmoid Cancer AJCC v7&apos; EquivalentTo &apos;Stage IV Colorectal Cancer AJCC v7&apos; and &apos;Rectosigmoid Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;)</deletedAxiom>
<newAxiom>&apos;Stage IV Rectosigmoid Cancer AJCC v7&apos; EquivalentTo &apos;Stage IV Colorectal Cancer AJCC v7&apos; and &apos;Rectosigmoid Cancer by AJCC v7 Stage&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Tenesmus&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153159</classIRI>
<classLabel>Actinium Ac-225 Anti-PSMA Monoclonal Antibody J591</classLabel>
<deletedAxiom>&apos;Actinium Ac-225 Anti-PSMA Monoclonal Antibody J591&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7399</classIRI>
<classLabel>Villous Adenoma</classLabel>
<deletedAxiom>&apos;Villous Adenoma&apos; EquivalentTo &apos;Adenoma&apos; and &apos;Glandular Cell Neoplasm&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Villous Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Exophytic Polypoid Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Tubular Pattern&apos;)</deletedAxiom>
<newAxiom>&apos;Villous Adenoma&apos; EquivalentTo &apos;Digestive System Adenoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Gastrointestinal Tract&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Villous Pattern&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Exophytic Polypoid Lesion&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Tubular Pattern&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142111</classIRI>
<classLabel>Neoplastic Plasma Cells More than 5 Percent of Peripheral Blood White Cells</classLabel>
<deletedAxiom>&apos;Neoplastic Plasma Cells More than 5 Percent of Peripheral Blood White Cells&apos; SubClassOf &apos;Atypical Lymphocytes Present in Peripheral Blood&apos;</deletedAxiom>
<newAxiom>&apos;Neoplastic Plasma Cells More than 5 Percent of Peripheral Blood White Cells&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176685</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65193</classIRI>
<classLabel>Flat Adenoma</classLabel>
<deletedAxiom>&apos;Flat Adenoma&apos; EquivalentTo &apos;Digestive System Adenoma&apos; and (&apos;Disease_Excludes_Finding&apos; some &apos;Exophytic Polypoid Lesion&apos;)</deletedAxiom>
<newAxiom>&apos;Flat Adenoma&apos; EquivalentTo &apos;Digestive System Adenoma&apos; and (&apos;Disease_Has_Primary_Anatomic_Site&apos; some &apos;Gastrointestinal Tract&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Exophytic Polypoid Lesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C117100</classIRI>
<classLabel>FBP1 Gene</classLabel>
<newAxiom>&apos;FBP1 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Gluconeogenic Process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156827</classIRI>
<classLabel>Current Smoker Includes Daily and Non-daily Smokers</classLabel>
<deletedAxiom>&apos;Current Smoker Includes Daily and Non-daily Smokers&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Current Smoker Includes Daily and Non-daily Smokers&apos; SubClassOf &apos;Smoking Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C117008</classIRI>
<classLabel>Satisfied with Information Received about Disease or Treatment</classLabel>
<newAxiom>&apos;Satisfied with Information Received about Disease or Treatment&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156687</classIRI>
<classLabel>Advanced Small Intestinal Neuroendocrine Carcinoma</classLabel>
<deletedAxiom>&apos;Advanced Small Intestinal Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Advanced Neuroendocrine Carcinoma&apos; and &apos;Metastatic Small Intestinal Neuroendocrine Carcinoma&apos; and &apos;Advanced Digestive System Carcinoma&apos; and &apos;Advanced Digestive System Neuroendocrine Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Advanced Small Intestinal Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Advanced Neuroendocrine Carcinoma&apos; and &apos;Metastatic Small Intestinal Neuroendocrine Carcinoma&apos; and &apos;Advanced Digestive System Carcinoma&apos; and &apos;Advanced Digestive System Neuroendocrine Neoplasm&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176679</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156681</classIRI>
<classLabel>PSMA/CD3 Tri-specific T-cell Activating Construct HPN424</classLabel>
<newAxiom>&apos;PSMA/CD3 Tri-specific T-cell Activating Construct HPN424&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156125</classIRI>
<classLabel>Ability to See Well Enough to Read Ordinary Newsprint</classLabel>
<newAxiom>&apos;Ability to See Well Enough to Read Ordinary Newsprint&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176426</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26270</classIRI>
<classLabel>Interleukin-10 Receptor Subunit Beta</classLabel>
<deletedAxiom>&apos;Interleukin-10 Receptor Subunit Beta&apos; EquivalentTo &apos;Cytokine Receptor&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;IL10 Anti-inflammatory Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cytokine-Cytokine Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Jak-STAT Signaling Pathway&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immune Response Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Receptor Signaling&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Interleukin Signaling Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;IL10RB Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Interleukin-10 Receptor Subunit Beta&apos; EquivalentTo &apos;Cytokine Receptor&apos; and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;IL10 Anti-inflammatory Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Cytokine-Cytokine Receptor Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Element_In_Pathway&apos; some &apos;Jak-STAT Signaling Pathway&apos;) and (&apos;Gene_Product_Is_Physical_Part_Of&apos; some http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176754) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Immune Response Process&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Receptor Signaling&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Interleukin Signaling Process&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;IL10RB Gene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156203</classIRI>
<classLabel>Had Great Difficulty When Trying to Think and Solve Day-to-day Problems</classLabel>
<deletedAxiom>&apos;Had Great Difficulty When Trying to Think and Solve Day-to-day Problems&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Had Great Difficulty When Trying to Think and Solve Day-to-day Problems&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156202</classIRI>
<classLabel>Had Some Difficulty When Trying to Think and Solve Day-to-day Problems</classLabel>
<deletedAxiom>&apos;Had Some Difficulty When Trying to Think and Solve Day-to-day Problems&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Had Some Difficulty When Trying to Think and Solve Day-to-day Problems&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156201</classIRI>
<classLabel>Had a Little Difficulty When Trying to Think and Solve Day-to-day Problems</classLabel>
<deletedAxiom>&apos;Had a Little Difficulty When Trying to Think and Solve Day-to-day Problems&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Had a Little Difficulty When Trying to Think and Solve Day-to-day Problems&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156188</classIRI>
<classLabel>Unable to Walk at All</classLabel>
<newAxiom>&apos;Unable to Walk at All&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156187</classIRI>
<classLabel>Unable to Walk Alone, Even with Walking Equipment; Able to Walk Short Distances with Help; Require Wheelchair to Get Around the Neighborhood</classLabel>
<newAxiom>&apos;Unable to Walk Alone, Even with Walking Equipment; Able to Walk Short Distances with Help; Require Wheelchair to Get Around the Neighborhood&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156186</classIRI>
<classLabel>Able to Walk Only Short Distances with Walking Equipment; Required a Wheelchair to Get Around the Neighborhood</classLabel>
<newAxiom>&apos;Able to Walk Only Short Distances with Walking Equipment; Required a Wheelchair to Get Around the Neighborhood&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156185</classIRI>
<classLabel>Able to Walk Around Neighborhood with Walking Equipment; No Help Required</classLabel>
<newAxiom>&apos;Able to Walk Around Neighborhood with Walking Equipment; No Help Required&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156184</classIRI>
<classLabel>Able to Walk Around Neighborhood with Difficulty; No Walking Equipment or Help Required</classLabel>
<newAxiom>&apos;Able to Walk Around Neighborhood with Difficulty; No Walking Equipment or Help Required&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156183</classIRI>
<classLabel>Able to Walk Around Neighborhood Without Difficulty; No Walking Equipment Needed</classLabel>
<newAxiom>&apos;Able to Walk Around Neighborhood Without Difficulty; No Walking Equipment Needed&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156149</classIRI>
<classLabel>Able to Hear with Hearing Aids</classLabel>
<newAxiom>&apos;Able to Hear with Hearing Aids&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176249</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156148</classIRI>
<classLabel>Able to Hear without Hearing Aids</classLabel>
<newAxiom>&apos;Able to Hear without Hearing Aids&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176249</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156152</classIRI>
<classLabel>Unable to Hear at All</classLabel>
<newAxiom>&apos;Unable to Hear at All&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176249</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156151</classIRI>
<classLabel>Unable to Hear, but did not Wear Hearing Aids</classLabel>
<newAxiom>&apos;Unable to Hear, but did not Wear Hearing Aids&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176249</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156150</classIRI>
<classLabel>Unable to Hear even with Hearing Aids</classLabel>
<newAxiom>&apos;Unable to Hear even with Hearing Aids&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176249</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122653</classIRI>
<classLabel>Dentatorubral-Pallidoluysian Atrophy</classLabel>
<newAxiom>&apos;Dentatorubral-Pallidoluysian Atrophy&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176696</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1333</classIRI>
<classLabel>Dexrazoxane</classLabel>
<deletedAxiom>&apos;Dexrazoxane&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Dexrazoxane&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1972</classIRI>
<classLabel>Deferoxamine Hydrochloride</classLabel>
<deletedAxiom>&apos;Deferoxamine Hydrochloride&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Deferoxamine Hydrochloride&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162569</classIRI>
<classLabel>Non-Metastatic Head and Neck Carcinoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Head and Neck Carcinoma&apos; EquivalentTo &apos;Head and Neck Carcinoma&apos; and &apos;Non-Metastatic Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Head and Neck Carcinoma&apos; EquivalentTo &apos;Head and Neck Carcinoma&apos; and &apos;Localized Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162570</classIRI>
<classLabel>Non-Metastatic Lung Carcinoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Lung Carcinoma&apos; EquivalentTo &apos;Lung Carcinoma&apos; and &apos;Non-Metastatic Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Lung Carcinoma&apos; EquivalentTo &apos;Lung Carcinoma&apos; and &apos;Localized Carcinoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12753</classIRI>
<classLabel>Mitral Valve</classLabel>
<deletedAxiom>&apos;Mitral Valve&apos; SubClassOf &apos;Cardiac Valve&apos;</deletedAxiom>
<newAxiom>&apos;Mitral Valve&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176322</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162650</classIRI>
<classLabel>Localized Metastasis</classLabel>
<deletedAxiom>&apos;Localized Metastasis&apos; SubClassOf &apos;Localized Disease&apos;</deletedAxiom>
<newAxiom>&apos;Localized Metastasis&apos; SubClassOf &apos;Clinical Course of Disease&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12805</classIRI>
<classLabel>Tricuspid Valve</classLabel>
<deletedAxiom>&apos;Tricuspid Valve&apos; SubClassOf &apos;Cardiac Valve&apos;</deletedAxiom>
<newAxiom>&apos;Tricuspid Valve&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176322</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C162638</classIRI>
<classLabel>Non-Metastatic Prostate Carcinoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Prostate Carcinoma&apos; EquivalentTo &apos;Prostate Carcinoma&apos; and &apos;Non-Metastatic Carcinoma&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Prostate Carcinoma&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1710</classIRI>
<classLabel>Pentetic Acid Calcium</classLabel>
<deletedAxiom>&apos;Pentetic Acid Calcium&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Pentetic Acid Calcium&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C416</classIRI>
<classLabel>Deferoxamine</classLabel>
<deletedAxiom>&apos;Deferoxamine&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Deferoxamine&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C417</classIRI>
<classLabel>Deferoxamine Mesylate</classLabel>
<deletedAxiom>&apos;Deferoxamine Mesylate&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Deferoxamine Mesylate&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C432</classIRI>
<classLabel>Ditiocarb</classLabel>
<deletedAxiom>&apos;Ditiocarb&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Ditiocarb&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C460</classIRI>
<classLabel>Pentetic Acid</classLabel>
<deletedAxiom>&apos;Pentetic Acid&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Pentetic Acid&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103305</classIRI>
<classLabel>Difficult to Look at Self Naked</classLabel>
<deletedAxiom>&apos;Difficult to Look at Self Naked&apos; SubClassOf &apos;Findings-Based Question&apos;</deletedAxiom>
<newAxiom>&apos;Difficult to Look at Self Naked&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103321</classIRI>
<classLabel>Important that I Look Good</classLabel>
<deletedAxiom>&apos;Important that I Look Good&apos; SubClassOf &apos;Findings-Based Question&apos;</deletedAxiom>
<newAxiom>&apos;Important that I Look Good&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103318</classIRI>
<classLabel>Careful to Buy Clothes that Make Me Look Good</classLabel>
<deletedAxiom>&apos;Careful to Buy Clothes that Make Me Look Good&apos; SubClassOf &apos;Findings-Based Question&apos;</deletedAxiom>
<newAxiom>&apos;Careful to Buy Clothes that Make Me Look Good&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142527</classIRI>
<classLabel>Electronic Data Capture</classLabel>
<deletedAxiom>&apos;Electronic Data Capture&apos; SubClassOf &apos;System&apos;</deletedAxiom>
<newAxiom>&apos;Electronic Data Capture&apos; SubClassOf &apos;Data Capture&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176003</classIRI>
<classLabel>Comfortable Calling Healthcare Provider About Symptom that May be Related to Return of Breast Cancer</classLabel>
<newAxiom>&apos;Comfortable Calling Healthcare Provider About Symptom that May be Related to Return of Breast Cancer&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176032</classIRI>
<classLabel>Never True</classLabel>
<newAxiom>&apos;Never True&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176245</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156982</classIRI>
<classLabel>Do Reading</classLabel>
<newAxiom>&apos;Do Reading&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176426</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91242</classIRI>
<classLabel>How Useful Numerical Information</classLabel>
<newAxiom>&apos;How Useful Numerical Information&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66633</classIRI>
<classLabel>Trientine</classLabel>
<deletedAxiom>&apos;Trientine&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Trientine&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27054</classIRI>
<classLabel>Rectal Hemorrhage</classLabel>
<deletedAxiom>&apos;Rectal Hemorrhage&apos; SubClassOf &apos;Intestinal Hemorrhage&apos;</deletedAxiom>
<newAxiom>&apos;Rectal Hemorrhage&apos; SubClassOf &apos;Lower Gastrointestinal Hemorrhage&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121819</classIRI>
<classLabel>Feel No Choice about Amount of Money Spent on Care</classLabel>
<newAxiom>&apos;Feel No Choice about Amount of Money Spent on Care&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121803</classIRI>
<classLabel>Have Difficulty Reading Because of Vision</classLabel>
<newAxiom>&apos;Have Difficulty Reading Because of Vision&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176426</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66945</classIRI>
<classLabel>Dexrazoxane Hydrochloride</classLabel>
<deletedAxiom>&apos;Dexrazoxane Hydrochloride&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Dexrazoxane Hydrochloride&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121737</classIRI>
<classLabel>Can Do With a Little Difficulty</classLabel>
<deletedAxiom>&apos;Can Do With a Little Difficulty&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Can Do With a Little Difficulty&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121736</classIRI>
<classLabel>Can Do Without Any Difficulty</classLabel>
<deletedAxiom>&apos;Can Do Without Any Difficulty&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Can Do Without Any Difficulty&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121739</classIRI>
<classLabel>Can Do With Some Difficulty</classLabel>
<deletedAxiom>&apos;Can Do With Some Difficulty&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Can Do With Some Difficulty&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121740</classIRI>
<classLabel>Can Do With Much Difficulty</classLabel>
<deletedAxiom>&apos;Can Do With Much Difficulty&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Can Do With Much Difficulty&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27449</classIRI>
<classLabel>Small Intestinal Small Cell Neuroendocrine Carcinoma</classLabel>
<deletedAxiom>&apos;Small Intestinal Small Cell Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Digestive System Small Cell Neuroendocrine Carcinoma&apos; and &apos;Small Intestinal Neuroendocrine Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Small Intestinal Small Cell Neuroendocrine Carcinoma&apos; EquivalentTo &apos;Digestive System Small Cell Neuroendocrine Carcinoma&apos; and &apos;Small Intestinal Neuroendocrine Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121438</classIRI>
<classLabel>No Independent Walking Ability</classLabel>
<newAxiom>&apos;No Independent Walking Ability&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121437</classIRI>
<classLabel>Inside Only Walking Ability</classLabel>
<deletedAxiom>&apos;Inside Only Walking Ability&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Inside Only Walking Ability&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121436</classIRI>
<classLabel>Greatly Limited Walking Ability</classLabel>
<deletedAxiom>&apos;Greatly Limited Walking Ability&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Greatly Limited Walking Ability&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121435</classIRI>
<classLabel>Limited Walking Ability</classLabel>
<deletedAxiom>&apos;Limited Walking Ability&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Limited Walking Ability&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121434</classIRI>
<classLabel>Reduced Walking Ability</classLabel>
<deletedAxiom>&apos;Reduced Walking Ability&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Reduced Walking Ability&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121433</classIRI>
<classLabel>Unlimited Walking Ability</classLabel>
<deletedAxiom>&apos;Unlimited Walking Ability&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Unlimited Walking Ability&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121405</classIRI>
<classLabel>Moderate Satisfaction with Extremity</classLabel>
<deletedAxiom>&apos;Moderate Satisfaction with Extremity&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Moderate Satisfaction with Extremity&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121404</classIRI>
<classLabel>Emotionally Satisfied with Extremity</classLabel>
<deletedAxiom>&apos;Emotionally Satisfied with Extremity&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Emotionally Satisfied with Extremity&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121211</classIRI>
<classLabel>Anti-CD47 Monoclonal Antibody CC-90002</classLabel>
<deletedAxiom>&apos;Anti-CD47 Monoclonal Antibody CC-90002&apos; SubClassOf &apos;Antineoplastic Antibody&apos;</deletedAxiom>
<newAxiom>&apos;Anti-CD47 Monoclonal Antibody CC-90002&apos; SubClassOf &apos;Anti-CD47 Monoclonal Antibody&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121220</classIRI>
<classLabel>Ability to Put on Shoes</classLabel>
<deletedAxiom>&apos;Ability to Put on Shoes&apos; SubClassOf &apos;Ability Question&apos;</deletedAxiom>
<newAxiom>&apos;Ability to Put on Shoes&apos; SubClassOf &apos;Dressing Ability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121241</classIRI>
<classLabel>Ability to Put on a Pair of Pants</classLabel>
<deletedAxiom>&apos;Ability to Put on a Pair of Pants&apos; SubClassOf &apos;Ability Question&apos;</deletedAxiom>
<newAxiom>&apos;Ability to Put on a Pair of Pants&apos; SubClassOf &apos;Dressing Ability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121243</classIRI>
<classLabel>Ability to Put on Socks or Stockings</classLabel>
<deletedAxiom>&apos;Ability to Put on Socks or Stockings&apos; SubClassOf &apos;Ability Question&apos;</deletedAxiom>
<newAxiom>&apos;Ability to Put on Socks or Stockings&apos; SubClassOf &apos;Dressing Ability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121246</classIRI>
<classLabel>Ability to Button a Shirt</classLabel>
<deletedAxiom>&apos;Ability to Button a Shirt&apos; SubClassOf &apos;Ability Question&apos;</deletedAxiom>
<newAxiom>&apos;Ability to Button a Shirt&apos; SubClassOf &apos;Dressing Ability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121391</classIRI>
<classLabel>Extremity Pain Between None and Modest</classLabel>
<deletedAxiom>&apos;Extremity Pain Between None and Modest&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Extremity Pain Between None and Modest&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176247</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121390</classIRI>
<classLabel>No Extremity Pain</classLabel>
<deletedAxiom>&apos;No Extremity Pain&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;No Extremity Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176247</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121395</classIRI>
<classLabel>Severe Extremity Pain</classLabel>
<deletedAxiom>&apos;Severe Extremity Pain&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Severe Extremity Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176247</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Moderate Extremity Pain</classLabel>
<deletedAxiom>&apos;Moderate Extremity Pain&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Moderate Extremity Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176247</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Extremity Pain Between Modest and Moderate</classLabel>
<deletedAxiom>&apos;Extremity Pain Between Modest and Moderate&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Extremity Pain Between Modest and Moderate&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176247</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Modest Extremity Pain</classLabel>
<deletedAxiom>&apos;Modest Extremity Pain&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Modest Extremity Pain&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176247</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Never, Under Any Circumstances Leak Urine or Lose Bladder Control</classLabel>
<deletedAxiom>&apos;Never, Under Any Circumstances Leak Urine or Lose Bladder Control&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Never, Under Any Circumstances Leak Urine or Lose Bladder Control&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176245</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Little Decrease of Sexual Drive or Interest</classLabel>
<deletedAxiom>&apos;Little Decrease of Sexual Drive or Interest&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Little Decrease of Sexual Drive or Interest&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176252</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Normal Amount of Sexual Drive and Interest</classLabel>
<deletedAxiom>&apos;Normal Amount of Sexual Drive and Interest&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Normal Amount of Sexual Drive and Interest&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176252</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Erections, But Not Firm Enough for Any Sexual Activity</classLabel>
<newAxiom>&apos;Erections, But Not Firm Enough for Any Sexual Activity&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176252</newAxiom>
</changedClass>
<changedClass>
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<classLabel>No Sexual Drive or Interest</classLabel>
<deletedAxiom>&apos;No Sexual Drive or Interest&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;No Sexual Drive or Interest&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176252</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C135636</classIRI>
<classLabel>Substantial Decrease of Sexual Drive or Interest</classLabel>
<deletedAxiom>&apos;Substantial Decrease of Sexual Drive or Interest&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Substantial Decrease of Sexual Drive or Interest&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176252</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Moderate Decrease of Sexual Drive or Interest</classLabel>
<deletedAxiom>&apos;Moderate Decrease of Sexual Drive or Interest&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Moderate Decrease of Sexual Drive or Interest&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176252</newAxiom>
</changedClass>
<changedClass>
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<classLabel>No Pain and No Disturbing Body Sensations</classLabel>
<deletedAxiom>&apos;No Pain and No Disturbing Body Sensations&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;No Pain and No Disturbing Body Sensations&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Severe Pain or Disturbing Body Sensations that Limit Many Activities</classLabel>
<deletedAxiom>&apos;Severe Pain or Disturbing Body Sensations that Limit Many Activities&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Severe Pain or Disturbing Body Sensations that Limit Many Activities&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C135584</classIRI>
<classLabel>Moderate to Severe Pain or Disturbing Body Sensations that Limit Some Activities</classLabel>
<deletedAxiom>&apos;Moderate to Severe Pain or Disturbing Body Sensations that Limit Some Activities&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Moderate to Severe Pain or Disturbing Body Sensations that Limit Some Activities&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Moderate Pain or Disturbing Body Sensations that Limit Few Activities</classLabel>
<deletedAxiom>&apos;Moderate Pain or Disturbing Body Sensations that Limit Few Activities&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Moderate Pain or Disturbing Body Sensations that Limit Few Activities&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
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<classLabel>Mild Pain or Disturbing Body Sensations Not Limiting Activities</classLabel>
<deletedAxiom>&apos;Mild Pain or Disturbing Body Sensations Not Limiting Activities&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Mild Pain or Disturbing Body Sensations Not Limiting Activities&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121166</classIRI>
<classLabel>Extremely Difficult</classLabel>
<deletedAxiom>&apos;Extremely Difficult&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Extremely Difficult&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121165</classIRI>
<classLabel>Somewhat Difficult</classLabel>
<deletedAxiom>&apos;Somewhat Difficult&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Somewhat Difficult&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
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<classLabel>More Difficult than Expected</classLabel>
<deletedAxiom>&apos;More Difficult than Expected&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;More Difficult than Expected&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160684</classIRI>
<classLabel>Tetrathiomolybdate</classLabel>
<deletedAxiom>&apos;Tetrathiomolybdate&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Tetrathiomolybdate&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101827</classIRI>
<classLabel>CDISC Questionnaire SF36 v2.0 Standard Test Name Terminology</classLabel>
<deletedAxiom>&apos;CDISC Questionnaire SF36 v2.0 Standard Test Name Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;CDISC Questionnaire SF36 v2.0 Standard Test Name Terminology&apos; SubClassOf &apos;CDISC Questionnaire Terminology&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101826</classIRI>
<classLabel>CDISC Questionnaire SF36 v2.0 Standard Test Code Terminology</classLabel>
<deletedAxiom>&apos;CDISC Questionnaire SF36 v2.0 Standard Test Code Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;CDISC Questionnaire SF36 v2.0 Standard Test Code Terminology&apos; SubClassOf &apos;CDISC Questionnaire Terminology&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101825</classIRI>
<classLabel>CDISC Questionnaire SF36 v2.0 Acute Test Name Terminology</classLabel>
<deletedAxiom>&apos;CDISC Questionnaire SF36 v2.0 Acute Test Name Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;CDISC Questionnaire SF36 v2.0 Acute Test Name Terminology&apos; SubClassOf &apos;CDISC Questionnaire Terminology&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101824</classIRI>
<classLabel>CDISC Questionnaire SF36 v1.0 Acute Test Name Terminology</classLabel>
<deletedAxiom>&apos;CDISC Questionnaire SF36 v1.0 Acute Test Name Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;CDISC Questionnaire SF36 v1.0 Acute Test Name Terminology&apos; SubClassOf &apos;CDISC Questionnaire Terminology&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101823</classIRI>
<classLabel>CDISC Questionnaire SF36 v1.0 Acute Test Code Terminology</classLabel>
<deletedAxiom>&apos;CDISC Questionnaire SF36 v1.0 Acute Test Code Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;CDISC Questionnaire SF36 v1.0 Acute Test Code Terminology&apos; SubClassOf &apos;CDISC Questionnaire Terminology&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101884</classIRI>
<classLabel>CDISC Questionnaire SF36 v2.0 Acute Test Code Terminology</classLabel>
<deletedAxiom>&apos;CDISC Questionnaire SF36 v2.0 Acute Test Code Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</deletedAxiom>
<newAxiom>&apos;CDISC Questionnaire SF36 v2.0 Acute Test Code Terminology&apos; SubClassOf &apos;CDISC Questionnaire Terminology&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174901</classIRI>
<classLabel>Mavacamten </classLabel>
<deletedAxiom>&apos;Mavacamten &apos; SubClassOf &apos;Inotropic Agent&apos;</deletedAxiom>
<newAxiom>&apos;Mavacamten &apos; SubClassOf &apos;Inotropic Support&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160220</classIRI>
<classLabel>Who Needed Medical Care but Family Unable to Afford it</classLabel>
<newAxiom>&apos;Who Needed Medical Care but Family Unable to Afford it&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160219</classIRI>
<classLabel>Needed Medical Care or Prescription Medicine but Unable to Afford it</classLabel>
<newAxiom>&apos;Needed Medical Care or Prescription Medicine but Unable to Afford it&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9050</classIRI>
<classLabel>Recurrent Lung Small Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Recurrent Lung Small Cell Carcinoma&apos; EquivalentTo &apos;Recurrent Neuroendocrine Carcinoma&apos; and &apos;Lung Small Cell Carcinoma&apos; and &apos;Recurrent Lung Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemoptysis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hoarseness&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Solitary Pulmonary Nodule&apos;)</deletedAxiom>
<newAxiom>&apos;Recurrent Lung Small Cell Carcinoma&apos; EquivalentTo &apos;Recurrent Neuroendocrine Carcinoma&apos; and http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176711 and &apos;Lung Small Cell Carcinoma&apos; and &apos;Recurrent Lung Carcinoma&apos; and (&apos;Disease_May_Have_Finding&apos; some &apos;Hemoptysis&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Hoarseness&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Solitary Pulmonary Nodule&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C86972</classIRI>
<classLabel>DNA Index</classLabel>
<deletedAxiom>&apos;DNA Index&apos; SubClassOf &apos;Property or Attribute&apos;</deletedAxiom>
<newAxiom>&apos;DNA Index&apos; SubClassOf &apos;Quantitative Concept&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47494</classIRI>
<classLabel>Dimercaprol</classLabel>
<deletedAxiom>&apos;Dimercaprol&apos; SubClassOf &apos;Metal Chelator&apos;</deletedAxiom>
<newAxiom>&apos;Dimercaprol&apos; SubClassOf &apos;Chelating Agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136333</classIRI>
<classLabel>A Medium Amount of Time</classLabel>
<deletedAxiom>&apos;A Medium Amount of Time&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;A Medium Amount of Time&apos; SubClassOf &apos;Time Frequency Answer&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C136332</classIRI>
<classLabel>A Very Short Time</classLabel>
<deletedAxiom>&apos;A Very Short Time&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;A Very Short Time&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176242</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175640</classIRI>
<classLabel>Ras-Related Protein Rab-35</classLabel>
<deletedAxiom>&apos;Ras-Related Protein Rab-35&apos; EquivalentTo &apos;RAS Superfamily Protein&apos; and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Membrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Endosome&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cytokinesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intracellular Transport&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RAB12 Gene&apos;)</deletedAxiom>
<newAxiom>&apos;Ras-Related Protein Rab-35&apos; EquivalentTo &apos;RAS Superfamily Protein&apos; and (&apos;Gene_Product_Has_Chemical_Classification&apos; some &apos;Membrane Protein&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Plasma Membrane&apos;) and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Membrane of the Endosome&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cytokinesis&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Intracellular Transport&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;RAB35 Gene&apos;)</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175455</classIRI>
<classLabel>Pain or Discomfort Answer</classLabel>
<deletedAxiom>&apos;Pain or Discomfort Answer&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Pain or Discomfort Answer&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9481</classIRI>
<classLabel>Non-Metastatic Carcinoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Carcinoma&apos; EquivalentTo &apos;Carcinoma&apos; and &apos;Non-Metastatic Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Carcinoma&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9448</classIRI>
<classLabel>Grade 3 Colorectal Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Grade 3 Colorectal Adenocarcinoma&apos; EquivalentTo &apos;Colorectal Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Poorly Differentiated Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 3&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Grade 3 Colorectal Adenocarcinoma&apos; EquivalentTo &apos;Colorectal Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Poorly Differentiated Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 3&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9447</classIRI>
<classLabel>Grade 2 Colorectal Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Grade 2 Colorectal Adenocarcinoma&apos; EquivalentTo &apos;Colorectal Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Moderately Differentiated Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 2&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Grade 2 Colorectal Adenocarcinoma&apos; EquivalentTo &apos;Colorectal Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Moderately Differentiated Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 2&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9446</classIRI>
<classLabel>Grade 1 Colorectal Adenocarcinoma</classLabel>
<deletedAxiom>&apos;Grade 1 Colorectal Adenocarcinoma&apos; EquivalentTo &apos;Colorectal Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Well Differentiated Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 1&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Intestinal Hemorrhage&apos;)</deletedAxiom>
<newAxiom>&apos;Grade 1 Colorectal Adenocarcinoma&apos; EquivalentTo &apos;Colorectal Adenocarcinoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Well Differentiated Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Grade 1&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Abdominal Pain&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Fever&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Weight Loss&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Constipation&apos;) and (&apos;Disease_May_Have_Finding&apos; some &apos;Lower Gastrointestinal Hemorrhage&apos;)</newAxiom>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9348</classIRI>
<classLabel>Mast Cell Sarcoma</classLabel>
<deletedAxiom>&apos;Mast Cell Sarcoma&apos; EquivalentTo &apos;Localized Malignant Neoplasm&apos; and &apos;Malignant Mastocytosis&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Immature Malignant Mast Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Unifocal Disease at Presentation&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Neoplastic Fibroblast&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Cutaneous Involvement&apos;)</deletedAxiom>
<newAxiom>&apos;Mast Cell Sarcoma&apos; EquivalentTo &apos;Malignant Mastocytosis&apos; and (&apos;Disease_Has_Abnormal_Cell&apos; some &apos;Immature Malignant Mast Cell&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;High Grade Lesion&apos;) and (&apos;Disease_Has_Finding&apos; some &apos;Unifocal Disease at Presentation&apos;) and (&apos;Disease_Excludes_Abnormal_Cell&apos; some &apos;Neoplastic Fibroblast&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Cutaneous Involvement&apos;) and (&apos;Disease_Excludes_Finding&apos; some &apos;Diffuse Lesion&apos;)</newAxiom>
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<classLabel>Autologous Anti-PSMA CAR-T Cells P-PSMA-101</classLabel>
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<classLabel>Ringing or Other Noises Answer</classLabel>
<deletedAxiom>&apos;Ringing or Other Noises Answer&apos; SubClassOf &apos;Clinical or Research Assessment Answer&apos;</deletedAxiom>
<newAxiom>&apos;Ringing or Other Noises Answer&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176249</newAxiom>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9275</classIRI>
<classLabel>Non-Metastatic Angiosarcoma</classLabel>
<deletedAxiom>&apos;Non-Metastatic Angiosarcoma&apos; EquivalentTo &apos;Angiosarcoma&apos; and &apos;Non-Metastatic Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Non-Metastatic Angiosarcoma&apos; EquivalentTo http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176558 and &apos;Angiosarcoma&apos;</newAxiom>
</changedClass>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102260</classIRI>
<classLabel>CD34 Measurement</classLabel>
<newAxiom>&apos;CD34 Measurement&apos; SubClassOf &apos;Protein or Enzyme Type Measurement&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C175364</classIRI>
<classLabel>Locally Recurrent Anal Canal Squamous Cell Carcinoma</classLabel>
<deletedAxiom>&apos;Locally Recurrent Anal Canal Squamous Cell Carcinoma&apos; EquivalentTo &apos;Recurrent Anal Canal Squamous Cell Carcinoma&apos; and &apos;Localized Carcinoma&apos; and &apos;Locally Recurrent Malignant Neoplasm&apos;</deletedAxiom>
<newAxiom>&apos;Locally Recurrent Anal Canal Squamous Cell Carcinoma&apos; EquivalentTo &apos;Recurrent Anal Canal Squamous Cell Carcinoma&apos; and &apos;Locally Recurrent Malignant Neoplasm&apos;</newAxiom>
</changedClass>
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<classLabel>Satisfied with Medical Care Received</classLabel>
<newAxiom>&apos;Satisfied with Medical Care Received&apos; SubClassOf http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</newAxiom>
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<classLabel>Thorium Th 227 Anti-PSMA Monoclonal Antibody BAY 2315497</classLabel>
<deletedAxiom>&apos;Thorium Th 227 Anti-PSMA Monoclonal Antibody BAY 2315497&apos; SubClassOf &apos;PSMA-targeting Agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C141214</classIRI>
<classLabel>Satisfaction with How Natural Your Reconstructed Nipples Look</classLabel>
<newAxiom>&apos;Satisfaction with How Natural Your Reconstructed Nipples Look&apos; SubClassOf &apos;Appearance Question&apos;</newAxiom>
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<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C92449</classIRI>
<classLabel>Childhood Abuse and Neglect</classLabel>
<deletedAxiom>&apos;Childhood Abuse and Neglect&apos; SubClassOf &apos;Event&apos;</deletedAxiom>
<newAxiom>&apos;Childhood Abuse and Neglect&apos; SubClassOf &apos;Retired Concept Current Year&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116342</classIRI>
<classLabel>Low Grade Astrocytic Tumor</classLabel>
<deletedAxiom>&apos;Low Grade Astrocytic Tumor&apos; EquivalentTo &apos;Low Grade Glioma&apos; and &apos;Astrocytic Tumor&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Low Grade Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Low Grade&apos;)</deletedAxiom>
<newAxiom>&apos;Low Grade Astrocytic Tumor&apos; EquivalentTo &apos;Low Grade Glioma&apos; and &apos;Astrocytoma&apos; and (&apos;Disease_Has_Finding&apos; some &apos;Low Grade Lesion&apos;) and (&apos;Disease_Is_Grade&apos; some &apos;Low Grade&apos;)</newAxiom>
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<classLabel>Dedicator of Cytokinesis Protein 8</classLabel>
<deletedAxiom>&apos;Dedicator of Cytokinesis Protein 8&apos; SubClassOf &apos;Gene_Product_Encoded_By_Gene&apos; some &apos;DOCK8 Gene&apos;</deletedAxiom>
<deletedAxiom>&apos;Dedicator of Cytokinesis Protein 8&apos; SubClassOf &apos;Signaling Protein&apos;</deletedAxiom>
<deletedAxiom>&apos;Dedicator of Cytokinesis Protein 8&apos; SubClassOf &apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cytosol&apos;</deletedAxiom>
<deletedAxiom>&apos;Dedicator of Cytokinesis Protein 8&apos; SubClassOf &apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;</deletedAxiom>
<newAxiom>&apos;Dedicator of Cytokinesis Protein 8&apos; EquivalentTo &apos;Guanine Nucleotide Exchange Factor&apos; and (&apos;Gene_Product_Has_Associated_Anatomy&apos; some &apos;Cytosol&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Cell-Mediated Immunity&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Signal Transduction&apos;) and (&apos;Gene_Product_Plays_Role_In_Biological_Process&apos; some &apos;Leukocyte Trafficking Induction&apos;) and (&apos;Gene_Product_Encoded_By_Gene&apos; some &apos;DOCK8 Gene&apos;)</newAxiom>
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<classLabel>DOCK8 Gene</classLabel>
<newAxiom>&apos;DOCK8 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Cell-Mediated Immunity&apos;</newAxiom>
<newAxiom>&apos;DOCK8 Gene&apos; SubClassOf &apos;Gene_Plays_Role_In_Process&apos; some &apos;Leukocyte Trafficking Induction&apos;</newAxiom>
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<classLabel>Proliferative Index</classLabel>
<deletedAxiom>&apos;Proliferative Index&apos; SubClassOf &apos;Property or Attribute&apos;</deletedAxiom>
<newAxiom>&apos;Proliferative Index&apos; SubClassOf &apos;Quantitative Concept&apos;</newAxiom>
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<changedClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116111</classIRI>
<classLabel>CDISC SDTM Species Terminology</classLabel>
<deletedAxiom>&apos;CDISC SDTM Species Terminology&apos; SubClassOf &apos;CDISC SDTM Terminology&apos;</deletedAxiom>
<newAxiom>&apos;CDISC SDTM Species Terminology&apos; SubClassOf &apos;Unused Subset Concept&apos;</newAxiom>
</changedClass>
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<classLabel>Immunodeficiency 26 with or without Neurologic Abnormalities</classLabel>
<newAxiom>'Immunodeficiency 26 with or without Neurologic Abnormalities' SubClassOf 'Severe Combined Immunodeficiency'</newAxiom>
<newAxiom>'Immunodeficiency 26 with or without Neurologic Abnormalities' SubClassOf 'Disease_Mapped_To_Gene' some 'PRKDC Gene'</newAxiom>
</newClass>
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<classLabel>Porcupine Inhibitor Wnt-C59</classLabel>
<newAxiom>'Porcupine Inhibitor Wnt-C59' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
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<classLabel>British Pharmacopeia</classLabel>
<newAxiom>'British Pharmacopeia' SubClassOf 'Information Resource'</newAxiom>
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<classLabel>Gastrointestinal Defects and Immunodeficiency Syndrome</classLabel>
<newAxiom>'Gastrointestinal Defects and Immunodeficiency Syndrome' SubClassOf 'Disease_Mapped_To_Gene' some 'TTC7A Gene'</newAxiom>
<newAxiom>'Gastrointestinal Defects and Immunodeficiency Syndrome' SubClassOf 'Syndrome'</newAxiom>
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<classLabel>DOCK2-Associated Immunodeficiency</classLabel>
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<newAxiom>'DOCK2-Associated Immunodeficiency' SubClassOf 'Disease_Mapped_To_Gene' some 'DOCK2 Gene'</newAxiom>
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<classLabel>Amendment to Supplement Submission</classLabel>
<newAxiom>'Amendment to Supplement Submission' SubClassOf 'Regulatory Submission'</newAxiom>
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<classLabel>Supplement to Original Submission</classLabel>
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<classLabel>Amendment to Original Submission</classLabel>
<newAxiom>'Amendment to Original Submission' SubClassOf 'Regulatory Submission'</newAxiom>
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<classLabel>47,XXY Karyotype</classLabel>
<newAxiom>'47,XXY Karyotype' SubClassOf 'Karyotype Status'</newAxiom>
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<classLabel>PARP Inhibitor AZD5305</classLabel>
<newAxiom>'PARP Inhibitor AZD5305' SubClassOf 'Poly (ADP-Ribose) Polymerase Inhibitor'</newAxiom>
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<classLabel>47,XYY Karyotype</classLabel>
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<classLabel>45,XO with Y Chromosomal Material</classLabel>
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<classLabel>PQ/CMC Application Submission Type Terminology</classLabel>
<newAxiom>'PQ/CMC Application Submission Type Terminology' SubClassOf 'FDA Pharmaceutical Quality/CMC Terminology'</newAxiom>
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<classLabel>48,XXXX Karyotype</classLabel>
<newAxiom>'48,XXXX Karyotype' SubClassOf 'Karyotype Status'</newAxiom>
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<classLabel>48,XXXY Karyotype</classLabel>
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<classLabel>47,XXX Karyotype</classLabel>
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<classLabel>PQ/CMC Co-Packaged Indicator Terminology</classLabel>
<newAxiom>'PQ/CMC Co-Packaged Indicator Terminology' SubClassOf 'FDA Pharmaceutical Quality/CMC Terminology'</newAxiom>
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<newAxiom>'B-Cell Expansion with NFKB and T-Cell Anergy' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
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<newAxiom>'PQ/CMC Process Related Impurity Category Terminology' SubClassOf 'FDA Pharmaceutical Quality/CMC Terminology'</newAxiom>
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<newAxiom>'Gallium Ga 68 NODAGA-LM3' SubClassOf 'Radioconjugate'</newAxiom>
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<newAxiom>'Autologous Anti-CD20 CAR T-cells C-CAR066' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Autologous Anti-CD20 CAR T-cells C-CAR066' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous Anti-CD20 CAR T-cells C-CAR066' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
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<classLabel>Anti-CFH Monoclonal Antibody GT103</classLabel>
<newAxiom>'Anti-CFH Monoclonal Antibody GT103' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-CFH Monoclonal Antibody GT103' SubClassOf 'Monoclonal Antibody'</newAxiom>
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<classLabel>HSV- thymidine Kinase-m2/hGM-CSF Genes-encoding GEN2</classLabel>
<newAxiom>'HSV- thymidine Kinase-m2/hGM-CSF Genes-encoding GEN2' SubClassOf 'Gene Therapy Agent'</newAxiom>
</newClass>
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<classLabel>Collagen Tile Brachytherapy</classLabel>
<newAxiom>'Collagen Tile Brachytherapy' SubClassOf 'Internal Radiation Therapy'</newAxiom>
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<classLabel>GammaTile</classLabel>
<newAxiom>'GammaTile' SubClassOf 'Radiation Source'</newAxiom>
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<classLabel>PI3K/mTOR Inhibitor HEC 68498</classLabel>
<newAxiom>'PI3K/mTOR Inhibitor HEC 68498' SubClassOf 'Phosphatidylinositide 3-Kinase Inhibitor'</newAxiom>
<newAxiom>'PI3K/mTOR Inhibitor HEC 68498' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
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<classLabel>Fluorine F 18 DPA-714</classLabel>
<newAxiom>'Fluorine F 18 DPA-714' SubClassOf 'Radioconjugate'</newAxiom>
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<classLabel>Tempol-containing MBM-02</classLabel>
<newAxiom>'Tempol-containing MBM-02' SubClassOf 'Chemoprotective Agent'</newAxiom>
<newAxiom>'Tempol-containing MBM-02' SubClassOf 'Radioprotective Agent'</newAxiom>
<newAxiom>'Tempol-containing MBM-02' SubClassOf 'Antioxidant'</newAxiom>
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<classLabel>Hip/Inguinal Region</classLabel>
<newAxiom>'Hip/Inguinal Region' SubClassOf 'Anatomic_Structure_Has_Location' some 'Abdomen'</newAxiom>
<newAxiom>'Hip/Inguinal Region' SubClassOf 'Body Region'</newAxiom>
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<classLabel>45,XO Karyotype</classLabel>
<newAxiom>'45,XO Karyotype' SubClassOf 'Karyotype Status'</newAxiom>
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<classLabel>Granulocyte Antibody Measurement</classLabel>
<newAxiom>'Granulocyte Antibody Measurement' SubClassOf 'Immunology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176761</classIRI>
<classLabel>Thyroid Peroxidase Antibody Measurement</classLabel>
<newAxiom>'Thyroid Peroxidase Antibody Measurement' SubClassOf 'Immunology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176760</classIRI>
<classLabel>Platelet Antibody Measurement</classLabel>
<newAxiom>'Platelet Antibody Measurement' SubClassOf 'Immunology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176766</classIRI>
<classLabel>Micro-immunotherapeutic Agent 2LEBV</classLabel>
<newAxiom>'Micro-immunotherapeutic Agent 2LEBV' SubClassOf 'Antineoplastic Biological Agent'</newAxiom>
<newAxiom>'Micro-immunotherapeutic Agent 2LEBV' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176765</classIRI>
<classLabel>ERK1/2 Inhibitor ATG-017</classLabel>
<newAxiom>'ERK1/2 Inhibitor ATG-017' SubClassOf 'ERK Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176764</classIRI>
<classLabel>Birthplace</classLabel>
<newAxiom>'Birthplace' SubClassOf 'Personal Attribute'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176763</classIRI>
<classLabel>Ancestry</classLabel>
<newAxiom>'Ancestry' SubClassOf 'Personal Attribute'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176769</classIRI>
<classLabel>Differentiated Anti-BCMA Autologous CAR T Cells ARI0002h</classLabel>
<newAxiom>'Differentiated Anti-BCMA Autologous CAR T Cells ARI0002h' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Differentiated Anti-BCMA Autologous CAR T Cells ARI0002h' SubClassOf 'Chemical_Or_Drug_Has_Mechanism_Of_Action' some 'Antigen Sensitization'</newAxiom>
<newAxiom>'Differentiated Anti-BCMA Autologous CAR T Cells ARI0002h' SubClassOf 'Chemical_Or_Drug_Affects_Cell_Type_Or_Tissue' some 'Cytotoxic T-Lymphocyte'</newAxiom>
<newAxiom>'Differentiated Anti-BCMA Autologous CAR T Cells ARI0002h' SubClassOf 'Anti-BCMA-targeting CAR-T Cells'</newAxiom>
<newAxiom>'Differentiated Anti-BCMA Autologous CAR T Cells ARI0002h' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'T-Cell Activation'</newAxiom>
<newAxiom>'Differentiated Anti-BCMA Autologous CAR T Cells ARI0002h' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Differentiated Anti-BCMA Autologous CAR T Cells ARI0002h' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Immunopotentiation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176768</classIRI>
<classLabel>IDH2 Mutant Inhibitor TQB3455</classLabel>
<newAxiom>'IDH2 Mutant Inhibitor TQB3455' SubClassOf 'IDH2 inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176767</classIRI>
<classLabel>Micro-immunotherapeutic Agent 2LXFS</classLabel>
<newAxiom>'Micro-immunotherapeutic Agent 2LXFS' SubClassOf 'Antineoplastic Biological Agent'</newAxiom>
<newAxiom>'Micro-immunotherapeutic Agent 2LXFS' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176751</classIRI>
<classLabel>JAK2 Inhibitor TQ05105</classLabel>
<newAxiom>'JAK2 Inhibitor TQ05105' SubClassOf 'JAK2 Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176750</classIRI>
<classLabel>CXCR1/2 Inhibitor RP72</classLabel>
<newAxiom>'CXCR1/2 Inhibitor RP72' SubClassOf 'Chemokine Receptor Antagonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176755</classIRI>
<classLabel>Follicular Helper T Cell</classLabel>
<newAxiom>'Follicular Helper T Cell' SubClassOf 'Helper-Inducer T-Lymphocyte'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176754</classIRI>
<classLabel>Interleukin 10 Receptor</classLabel>
<newAxiom>'Interleukin 10 Receptor' SubClassOf 'Protein or Riboprotein Complex'</newAxiom>
<newAxiom>'Interleukin 10 Receptor' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Ligand Binding'</newAxiom>
<newAxiom>'Interleukin 10 Receptor' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Receptor Signaling'</newAxiom>
<newAxiom>'Interleukin 10 Receptor' SubClassOf 'Gene_Product_Has_Biochemical_Function' some 'Cytokine Receptor'</newAxiom>
<newAxiom>'Interleukin 10 Receptor' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Interleukin Signaling Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176753</classIRI>
<classLabel>Lindera obtusiloba Extract</classLabel>
<newAxiom>'Lindera obtusiloba Extract' SubClassOf 'Dietary Supplement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176752</classIRI>
<classLabel>NEMO Deleted Exon 5 Autoinflammatory Syndrome</classLabel>
<newAxiom>'NEMO Deleted Exon 5 Autoinflammatory Syndrome' SubClassOf 'Autoinflammatory Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176759</classIRI>
<classLabel>Nuclear Pore gp120 Antibody Measurement</classLabel>
<newAxiom>'Nuclear Pore gp120 Antibody Measurement' SubClassOf 'Immunology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176758</classIRI>
<classLabel>SP100 Antibody Measurement</classLabel>
<newAxiom>'SP100 Antibody Measurement' SubClassOf 'Immunology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176757</classIRI>
<classLabel>Tumor-Infiltrating T Helper 17 Cell</classLabel>
<newAxiom>'Tumor-Infiltrating T Helper 17 Cell' SubClassOf 'Tumor Infiltrating Lymphocyte'</newAxiom>
<newAxiom>'Tumor-Infiltrating T Helper 17 Cell' SubClassOf 'T Helper 17 Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176756</classIRI>
<classLabel>Tumor-Infiltrating Follicular Helper T Cell</classLabel>
<newAxiom>'Tumor-Infiltrating Follicular Helper T Cell' SubClassOf 'Follicular Helper T Cell'</newAxiom>
<newAxiom>'Tumor-Infiltrating Follicular Helper T Cell' SubClassOf 'Tumor Infiltrating Lymphocyte'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176740</classIRI>
<classLabel>Interferon Gamma-primed Human Bone Marrow-derived Mesenchymal Stromal Cells</classLabel>
<newAxiom>'Interferon Gamma-primed Human Bone Marrow-derived Mesenchymal Stromal Cells' SubClassOf 'Adoptive Cell Therapy Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176744</classIRI>
<classLabel>Anti-CD47/Anti-PD-L1 Bispecific Antibody IBI322</classLabel>
<newAxiom>'Anti-CD47/Anti-PD-L1 Bispecific Antibody IBI322' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-CD47/Anti-PD-L1 Bispecific Antibody IBI322' SubClassOf 'Bispecific Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176743</classIRI>
<classLabel>Eye Tracking via Glasses</classLabel>
<newAxiom>'Eye Tracking via Glasses' SubClassOf 'Eye Tracking'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176742</classIRI>
<classLabel>Eye Tracking</classLabel>
<newAxiom>'Eye Tracking' SubClassOf 'Diagnostic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176741</classIRI>
<classLabel>Eye-Tracking Glasses</classLabel>
<newAxiom>'Eye-Tracking Glasses' SubClassOf 'Glasses'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176748</classIRI>
<classLabel>Oncolytic Herpes Simplex Virus-1 Expressing Anti-CTLA-4 Antibody-like Molecule and GM-CSF RP2</classLabel>
<newAxiom>'Oncolytic Herpes Simplex Virus-1 Expressing Anti-CTLA-4 Antibody-like Molecule and GM-CSF RP2' SubClassOf 'Oncolytic Virus'</newAxiom>
<newAxiom>'Oncolytic Herpes Simplex Virus-1 Expressing Anti-CTLA-4 Antibody-like Molecule and GM-CSF RP2' SubClassOf 'Gene Therapy Agent'</newAxiom>
<newAxiom>'Oncolytic Herpes Simplex Virus-1 Expressing Anti-CTLA-4 Antibody-like Molecule and GM-CSF RP2' SubClassOf 'Immunostimulant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176747</classIRI>
<classLabel>IKKb-matured RNA-loaded Autologous Dendritic Cells DCIKKb</classLabel>
<newAxiom>'IKKb-matured RNA-loaded Autologous Dendritic Cells DCIKKb' SubClassOf 'Dendritic Cell Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176746</classIRI>
<classLabel>Anti-TIGIT Monoclonal Antibody EOS884448</classLabel>
<newAxiom>'Anti-TIGIT Monoclonal Antibody EOS884448' SubClassOf 'Antineoplastic Antibody'</newAxiom>
<newAxiom>'Anti-TIGIT Monoclonal Antibody EOS884448' SubClassOf 'Anti-TIGIT Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176745</classIRI>
<classLabel>Factor D Inhibitor BCX9930</classLabel>
<newAxiom>'Factor D Inhibitor BCX9930' SubClassOf 'Immunotherapeutic Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176749</classIRI>
<classLabel>TLR7 Agonist RO7119929</classLabel>
<newAxiom>'TLR7 Agonist RO7119929' SubClassOf 'Immunostimulant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176733</classIRI>
<classLabel>Variant Autoimmune Hepatitis</classLabel>
<newAxiom>'Variant Autoimmune Hepatitis' SubClassOf 'Autoimmune Hepatitis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176732</classIRI>
<classLabel>Type 2 Autoimmune Hepatitis</classLabel>
<newAxiom>'Type 2 Autoimmune Hepatitis' SubClassOf 'Autoimmune Hepatitis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176731</classIRI>
<classLabel>Type 1 Autoimmune Hepatitis</classLabel>
<newAxiom>'Type 1 Autoimmune Hepatitis' SubClassOf 'Autoimmune Hepatitis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176730</classIRI>
<classLabel>Autoimmune Neutropenia</classLabel>
<newAxiom>'Autoimmune Neutropenia' SubClassOf 'Autoimmune Cytopenia'</newAxiom>
<newAxiom>'Autoimmune Neutropenia' SubClassOf 'Neutropenia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176737</classIRI>
<classLabel>Respiratory Band</classLabel>
<newAxiom>'Respiratory Band' SubClassOf 'Instrumentation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176736</classIRI>
<classLabel>EEG Monitoring via Cap</classLabel>
<newAxiom>'EEG Monitoring via Cap' SubClassOf 'Electroencephalography'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176735</classIRI>
<classLabel>Electroencephalography Cap</classLabel>
<newAxiom>'Electroencephalography Cap' SubClassOf 'Instrumentation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176734</classIRI>
<classLabel>Neutrophilic Dermatosis</classLabel>
<newAxiom>'Neutrophilic Dermatosis' SubClassOf 'Dermatosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176739</classIRI>
<classLabel>Accelerometry</classLabel>
<newAxiom>'Accelerometry' SubClassOf 'Diagnostic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176738</classIRI>
<classLabel>Respiratory Monitoring via Band</classLabel>
<newAxiom>'Respiratory Monitoring via Band' SubClassOf 'Pulmonary Function Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176722</classIRI>
<classLabel>Diagnostic Criteria Met</classLabel>
<newAxiom>'Diagnostic Criteria Met' SubClassOf 'Medical Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176721</classIRI>
<classLabel>Diagnostic Criteria Not Met</classLabel>
<newAxiom>'Diagnostic Criteria Not Met' SubClassOf 'Medical Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176720</classIRI>
<classLabel>Medication Status</classLabel>
<newAxiom>'Medication Status' SubClassOf 'Treatment Status'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176726</classIRI>
<classLabel>Transplant Complication</classLabel>
<newAxiom>'Transplant Complication' SubClassOf 'Complication due to Medical/Surgical Care'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176725</classIRI>
<classLabel>Prosthetic Complication</classLabel>
<newAxiom>'Prosthetic Complication' SubClassOf 'Device Complication'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176724</classIRI>
<classLabel>Absence of Sequelae</classLabel>
<newAxiom>'Absence of Sequelae' SubClassOf 'Clinical Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176723</classIRI>
<classLabel>No Alleviating Factor</classLabel>
<newAxiom>'No Alleviating Factor' SubClassOf 'Clinical Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176729</classIRI>
<classLabel>PALB2-Associated Malignant Neoplasm</classLabel>
<newAxiom>'PALB2-Associated Malignant Neoplasm' EquivalentTo 'Hereditary Malignant Neoplasm' and ('Disease_Has_Molecular_Abnormality' some 'Deleterious PALB2 Gene Mutation')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176728</classIRI>
<classLabel>Locally Advanced Unresectable Primary Central Chondrosarcoma</classLabel>
<newAxiom>'Locally Advanced Unresectable Primary Central Chondrosarcoma' EquivalentTo 'Locally Advanced Unresectable Bone Sarcoma' and 'Locally Advanced Chondrosarcoma' and 'Unresectable Primary Central Chondrosarcoma' and 'Metastatic Primary Central Chondrosarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176727</classIRI>
<classLabel>Advanced Lung Adenocarcinoma</classLabel>
<newAxiom>'Advanced Lung Adenocarcinoma' EquivalentTo 'Advanced Lung Non-Squamous Non-Small Cell Carcinoma' and 'Metastatic Lung Adenocarcinoma' and 'Advanced Adenocarcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176711</classIRI>
<classLabel>Recurrent Lung Neuroendocrine Neoplasm</classLabel>
<newAxiom>'Recurrent Lung Neuroendocrine Neoplasm' EquivalentTo 'Recurrent Neuroendocrine Neoplasm' and 'Lung Neuroendocrine Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176710</classIRI>
<classLabel>Breast Examination Finding</classLabel>
<newAxiom>'Breast Examination Finding' SubClassOf 'Physical Examination Finding'</newAxiom>
<newAxiom>'Breast Examination Finding' SubClassOf 'Breast Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176715</classIRI>
<classLabel>Locally Advanced Lung Neuroendocrine Neoplasm</classLabel>
<newAxiom>'Locally Advanced Lung Neuroendocrine Neoplasm' EquivalentTo 'Metastatic Lung Neuroendocrine Neoplasm' and 'Locally Advanced Neuroendocrine Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176714</classIRI>
<classLabel>Complaint</classLabel>
<newAxiom>'Complaint' SubClassOf 'Symptom'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176713</classIRI>
<classLabel>Abuse</classLabel>
<newAxiom>'Abuse' SubClassOf 'Personal Behavior'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176712</classIRI>
<classLabel>Cancer-related Symptom</classLabel>
<newAxiom>'Cancer-related Symptom' SubClassOf 'Symptom'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176719</classIRI>
<classLabel>Lymph Node Finding</classLabel>
<newAxiom>'Lymph Node Finding' SubClassOf 'Immune System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176718</classIRI>
<classLabel>Physiological Condition</classLabel>
<newAxiom>'Physiological Condition' SubClassOf 'Condition'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176717</classIRI>
<classLabel>Tissue or Organ Disruption</classLabel>
<newAxiom>'Tissue or Organ Disruption' SubClassOf 'Congenital or Acquired Anatomic Abnormality'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176716</classIRI>
<classLabel>Exercise Tolerance Test Result</classLabel>
<newAxiom>'Exercise Tolerance Test Result' SubClassOf 'Clinical Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176700</classIRI>
<classLabel>Phosphorus-32 Beta Radiation</classLabel>
<newAxiom>'Phosphorus-32 Beta Radiation' SubClassOf 'Beta Radiation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176704</classIRI>
<classLabel>YARSopathy</classLabel>
<newAxiom>'YARSopathy' SubClassOf 'Rare Non-Neoplastic Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176703</classIRI>
<classLabel>PIK3R1-Associated Immunodeficiency</classLabel>
<newAxiom>'PIK3R1-Associated Immunodeficiency' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176702</classIRI>
<classLabel>Feline Progressive Histiocytosis</classLabel>
<newAxiom>'Feline Progressive Histiocytosis' SubClassOf 'Feline Experimental Organism Diagnosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176701</classIRI>
<classLabel>Canine Sebaceous Gland Epithelioma</classLabel>
<newAxiom>'Canine Sebaceous Gland Epithelioma' SubClassOf 'Canine Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176708</classIRI>
<classLabel>Imaging Finding</classLabel>
<newAxiom>'Imaging Finding' SubClassOf 'Clinical Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176707</classIRI>
<classLabel>Physical Examination Finding</classLabel>
<newAxiom>'Physical Examination Finding' SubClassOf 'Retired Concept Current Year'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176706</classIRI>
<classLabel>Non-Functioning Lung Carcinoid Tumor</classLabel>
<newAxiom>'Non-Functioning Lung Carcinoid Tumor' EquivalentTo 'Lung Carcinoid Tumor' and 'Non-Functioning Endocrine Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176705</classIRI>
<classLabel>Functioning Lung Carcinoid Tumor</classLabel>
<newAxiom>'Functioning Lung Carcinoid Tumor' EquivalentTo 'Lung Carcinoid Tumor' and 'Functioning Endocrine Neoplasm' and ('Disease_Has_Associated_Disease' some 'Carcinoid Syndrome')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176709</classIRI>
<classLabel>Breast Finding</classLabel>
<newAxiom>'Breast Finding' SubClassOf 'Female Reproductive System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176810</classIRI>
<classLabel>Microbiological Property</classLabel>
<newAxiom>'Microbiological Property' SubClassOf 'Organism Characteristic'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176814</classIRI>
<classLabel>PQ/CMC Product Related Impurity Category Terminology</classLabel>
<newAxiom>'PQ/CMC Product Related Impurity Category Terminology' SubClassOf 'FDA Pharmaceutical Quality/CMC Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176813</classIRI>
<classLabel>Product Related Impurity</classLabel>
<newAxiom>'Product Related Impurity' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176812</classIRI>
<classLabel>Process Related Impurity</classLabel>
<newAxiom>'Process Related Impurity' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176811</classIRI>
<classLabel>Physico-Chemical Properties</classLabel>
<newAxiom>'Physico-Chemical Properties' SubClassOf 'Physical Object Property'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176818</classIRI>
<classLabel>Neutropenia, Severe Congenital, X-Linked</classLabel>
<newAxiom>'Neutropenia, Severe Congenital, X-Linked' SubClassOf 'Disease_Mapped_To_Gene' some 'WAS Gene'</newAxiom>
<newAxiom>'Neutropenia, Severe Congenital, X-Linked' SubClassOf 'Severe Congenital Neutropenia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176817</classIRI>
<classLabel>Purine Nucleoside Phosphorylase Deficiency</classLabel>
<newAxiom>'Purine Nucleoside Phosphorylase Deficiency' SubClassOf 'Immune System Disorder'</newAxiom>
<newAxiom>'Purine Nucleoside Phosphorylase Deficiency' SubClassOf 'Disease_Mapped_To_Gene' some 'PNP Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176816</classIRI>
<classLabel>Degradant</classLabel>
<newAxiom>'Degradant' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176815</classIRI>
<classLabel>Residual Solvent</classLabel>
<newAxiom>'Residual Solvent' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176819</classIRI>
<classLabel>Warts, Hypogammaglobulinemia, Infections, and Myelokathexis Syndrome</classLabel>
<newAxiom>'Warts, Hypogammaglobulinemia, Infections, and Myelokathexis Syndrome' SubClassOf 'Disease_Mapped_To_Gene' some 'CXCR4 Gene'</newAxiom>
<newAxiom>'Warts, Hypogammaglobulinemia, Infections, and Myelokathexis Syndrome' SubClassOf 'Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176803</classIRI>
<classLabel>Amendment to Master Drug File</classLabel>
<newAxiom>'Amendment to Master Drug File' SubClassOf 'Regulatory Submission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176802</classIRI>
<classLabel>Amendment to Investigational New Drug</classLabel>
<newAxiom>'Amendment to Investigational New Drug' SubClassOf 'Regulatory Submission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176801</classIRI>
<classLabel>Immunodeficiency, Common Variable, 11</classLabel>
<newAxiom>'Immunodeficiency, Common Variable, 11' SubClassOf 'Disease_Mapped_To_Gene' some 'IL21 Gene'</newAxiom>
<newAxiom>'Immunodeficiency, Common Variable, 11' SubClassOf 'Common Variable Immunodeficiency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176800</classIRI>
<classLabel>IL12RB1-Associated Immunodeficiency</classLabel>
<newAxiom>'IL12RB1-Associated Immunodeficiency' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
<newAxiom>'IL12RB1-Associated Immunodeficiency' SubClassOf 'Disease_Mapped_To_Gene' some 'IL12RB1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176807</classIRI>
<classLabel>Severe Combined Immunodeficiency, Autosomal Recessive, T-Cell Negative, B-Cell Positive, NK-Cell Negative</classLabel>
<newAxiom>'Severe Combined Immunodeficiency, Autosomal Recessive, T-Cell Negative, B-Cell Positive, NK-Cell Negative' SubClassOf 'Severe Combined Immunodeficiency'</newAxiom>
<newAxiom>'Severe Combined Immunodeficiency, Autosomal Recessive, T-Cell Negative, B-Cell Positive, NK-Cell Negative' SubClassOf 'Disease_Mapped_To_Gene' some 'JAK3 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176806</classIRI>
<classLabel>Interferon Gamma Receptor 1 Deficiency</classLabel>
<newAxiom>'Interferon Gamma Receptor 1 Deficiency' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
<newAxiom>'Interferon Gamma Receptor 1 Deficiency' SubClassOf 'Disease_Mapped_To_Gene' some 'IFNGR1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176805</classIRI>
<classLabel>Interferon Gamma Receptor 2 Deficiency</classLabel>
<newAxiom>'Interferon Gamma Receptor 2 Deficiency' SubClassOf 'Disease_Mapped_To_Gene' some 'IFNGR2 Gene'</newAxiom>
<newAxiom>'Interferon Gamma Receptor 2 Deficiency' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176804</classIRI>
<classLabel>Severe Combined Immunodeficiency, Autosomal Recessive, T-Cell Negative, B Cell-Positive, NK Cell-Positive</classLabel>
<newAxiom>'Severe Combined Immunodeficiency, Autosomal Recessive, T-Cell Negative, B Cell-Positive, NK Cell-Positive' SubClassOf 'Severe Combined Immunodeficiency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176809</classIRI>
<classLabel>Immunodeficiency, Common Variable, 8, with Autoimmunity</classLabel>
<newAxiom>'Immunodeficiency, Common Variable, 8, with Autoimmunity' SubClassOf 'Disease_Mapped_To_Gene' some 'LRBA Gene'</newAxiom>
<newAxiom>'Immunodeficiency, Common Variable, 8, with Autoimmunity' SubClassOf 'Common Variable Immunodeficiency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176808</classIRI>
<classLabel>LCK-Associated Immunodeficiency</classLabel>
<newAxiom>'LCK-Associated Immunodeficiency' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
<newAxiom>'LCK-Associated Immunodeficiency' SubClassOf 'Disease_Mapped_To_Gene' some 'LCK Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176850</classIRI>
<classLabel>Allogeneic Anti-CD19 1XX-CAR T-cells FT819</classLabel>
<newAxiom>'Allogeneic Anti-CD19 1XX-CAR T-cells FT819' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Allogeneic Anti-CD19 1XX-CAR T-cells FT819' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Allogeneic Anti-CD19 1XX-CAR T-cells FT819' SubClassOf 'Anti-CD19-targeting CAR-T Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176854</classIRI>
<classLabel>High Resolution Anoscopy</classLabel>
<newAxiom>'High Resolution Anoscopy' SubClassOf 'Diagnostic Endoscopic Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176853</classIRI>
<classLabel>Lutetium Lu 177-DOTA-ABM-5G</classLabel>
<newAxiom>'Lutetium Lu 177-DOTA-ABM-5G' SubClassOf 'Radioconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176852</classIRI>
<classLabel>Gallium Ga 68-DOTA-5G</classLabel>
<newAxiom>'Gallium Ga 68-DOTA-5G' SubClassOf 'Radioconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176851</classIRI>
<classLabel>CXCR2 Agonist MGTA-145</classLabel>
<newAxiom>'CXCR2 Agonist MGTA-145' SubClassOf 'Pharmacologic Substance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176858</classIRI>
<classLabel>Refractory Lung Non-Squamous Non-Small Cell Carcinoma</classLabel>
<newAxiom>'Refractory Lung Non-Squamous Non-Small Cell Carcinoma' EquivalentTo 'Lung Non-Squamous Non-Small Cell Carcinoma' and 'Refractory Lung Non-Small Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176857</classIRI>
<classLabel>Locally Advanced Lung Small Cell Carcinoma</classLabel>
<newAxiom>'Locally Advanced Lung Small Cell Carcinoma' EquivalentTo 'Locally Advanced Lung Carcinoma' and 'Metastatic Lung Small Cell Carcinoma' and 'Locally Advanced Small Cell Neuroendocrine Carcinoma' and 'Locally Advanced Lung Neuroendocrine Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176856</classIRI>
<classLabel>Microscopy with Ultraviolet Surface Excitation</classLabel>
<newAxiom>'Microscopy with Ultraviolet Surface Excitation' SubClassOf 'Ultraviolet Microscopy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176855</classIRI>
<classLabel>LentiGlobin BB305 Lentiviral Vector-transduced Autologous SCD CD34+ Hemaptopoietic Stem Cells bb1111</classLabel>
<newAxiom>'LentiGlobin BB305 Lentiviral Vector-transduced Autologous SCD CD34+ Hemaptopoietic Stem Cells bb1111' SubClassOf 'Genetically-engineered Immune Cell'</newAxiom>
<newAxiom>'LentiGlobin BB305 Lentiviral Vector-transduced Autologous SCD CD34+ Hemaptopoietic Stem Cells bb1111' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176843</classIRI>
<classLabel>Recombinant Newcastle Disease Virus-encoding Interleukin-12 MEDI9253</classLabel>
<newAxiom>'Recombinant Newcastle Disease Virus-encoding Interleukin-12 MEDI9253' SubClassOf 'Oncolytic Virus'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176842</classIRI>
<classLabel>SP100 Gene</classLabel>
<newAxiom>'SP100 Gene' SubClassOf 'Transcription Factor Gene'</newAxiom>
<newAxiom>'SP100 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Tumor Suppression'</newAxiom>
<newAxiom>'SP100 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Activation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176841</classIRI>
<classLabel>Vibostolimab/Pembrolizumab MK-7684A</classLabel>
<newAxiom>'Vibostolimab/Pembrolizumab MK-7684A' SubClassOf 'Anti-TIGIT Monoclonal Antibody'</newAxiom>
<newAxiom>'Vibostolimab/Pembrolizumab MK-7684A' SubClassOf 'Anti-PD1 Monoclonal Antibody'</newAxiom>
<newAxiom>'Vibostolimab/Pembrolizumab MK-7684A' SubClassOf 'Antineoplastic Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176840</classIRI>
<classLabel>Survivor Unmet Needs Survey</classLabel>
<newAxiom>'Survivor Unmet Needs Survey' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176847</classIRI>
<classLabel>Pneumatic Compression Therapy</classLabel>
<newAxiom>'Pneumatic Compression Therapy' SubClassOf 'Compression Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176846</classIRI>
<classLabel>Antisense Oligonucleotide ION537</classLabel>
<newAxiom>'Antisense Oligonucleotide ION537' SubClassOf 'Antisense Oligonucleotides'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176845</classIRI>
<classLabel>Nuclear Autoantigen Sp-100</classLabel>
<newAxiom>'Nuclear Autoantigen Sp-100' EquivalentTo 'Transcription Factor' and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'HMG-Box') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Coiled-Coil Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Nuclear Localization Signal') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Tumor Suppression') and ('Gene_Product_Encoded_By_Gene' some 'SP100 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176844</classIRI>
<classLabel>SP100 wt Allele</classLabel>
<newAxiom>'SP100 wt Allele' SubClassOf 'SP100 Gene'</newAxiom>
<newAxiom>'SP100 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '2q37.1'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176849</classIRI>
<classLabel>Healthcare Utilization</classLabel>
<newAxiom>'Healthcare Utilization' SubClassOf 'Healthcare Activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176848</classIRI>
<classLabel>Pneumatic Compression Therapy with Reminders</classLabel>
<newAxiom>'Pneumatic Compression Therapy with Reminders' SubClassOf 'Pneumatic Compression Therapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176832</classIRI>
<classLabel>Financial Hardship</classLabel>
<newAxiom>'Financial Hardship' SubClassOf 'Personal Attribute'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176831</classIRI>
<classLabel>CDK2/4/6 Inhibitor NUV-422</classLabel>
<newAxiom>'CDK2/4/6 Inhibitor NUV-422' SubClassOf 'Cyclin-Dependent Kinase Inhibitor'</newAxiom>
<newAxiom>'CDK2/4/6 Inhibitor NUV-422' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176830</classIRI>
<classLabel>Fear of Cancer Recurrence Questionnaire</classLabel>
<newAxiom>'Fear of Cancer Recurrence Questionnaire' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176836</classIRI>
<classLabel>EORTC Quality of Life Questionnaire-Core 30</classLabel>
<newAxiom>'EORTC Quality of Life Questionnaire-Core 30' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176835</classIRI>
<classLabel>CAHPS Cancer Care Survey</classLabel>
<newAxiom>'CAHPS Cancer Care Survey' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176834</classIRI>
<classLabel>CD38-targeting Antibody Recruiting Molecule KP1237</classLabel>
<newAxiom>'CD38-targeting Antibody Recruiting Molecule KP1237' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176833</classIRI>
<classLabel>Patient-Centered Communication in Cancer Care-Long Form</classLabel>
<newAxiom>'Patient-Centered Communication in Cancer Care-Long Form' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176839</classIRI>
<classLabel>Supportive Care Needs Survey-Short Form 34</classLabel>
<newAxiom>'Supportive Care Needs Survey-Short Form 34' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176838</classIRI>
<classLabel>Quality of Life Patient/Cancer Survivor Version</classLabel>
<newAxiom>'Quality of Life Patient/Cancer Survivor Version' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176837</classIRI>
<classLabel>Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being 12 Item Scale</classLabel>
<newAxiom>'Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being 12 Item Scale' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176821</classIRI>
<classLabel>Immunodeficiency 48; Selective T-Cell Defect; STCD</classLabel>
<newAxiom>'Immunodeficiency 48; Selective T-Cell Defect; STCD' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
<newAxiom>'Immunodeficiency 48; Selective T-Cell Defect; STCD' SubClassOf 'Disease_Mapped_To_Gene' some 'ZAP70 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176820</classIRI>
<classLabel>Wiskott-Aldrich Syndrome 2</classLabel>
<newAxiom>'Wiskott-Aldrich Syndrome 2' SubClassOf 'Disease_Mapped_To_Gene' some 'WIPF1 Gene'</newAxiom>
<newAxiom>'Wiskott-Aldrich Syndrome 2' SubClassOf 'Syndrome'</newAxiom>
<newAxiom>'Wiskott-Aldrich Syndrome 2' SubClassOf 'Congenital Combined Immunodeficiency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176825</classIRI>
<classLabel>Interferon Regulatory Factor 8 Deficiency</classLabel>
<newAxiom>'Interferon Regulatory Factor 8 Deficiency' SubClassOf 'Disease_Mapped_To_Gene' some 'IRF8 Gene'</newAxiom>
<newAxiom>'Interferon Regulatory Factor 8 Deficiency' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176824</classIRI>
<classLabel>Autologous Anti-HER2 CAR Macrophages CT-0508</classLabel>
<newAxiom>'Autologous Anti-HER2 CAR Macrophages CT-0508' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176823</classIRI>
<classLabel>MHC Class II Deficiency</classLabel>
<newAxiom>'MHC Class II Deficiency' SubClassOf 'Severe Combined Immunodeficiency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176822</classIRI>
<classLabel>Autosomal Recessive Agammaglobulinemia</classLabel>
<newAxiom>'Autosomal Recessive Agammaglobulinemia' SubClassOf 'Hypogammaglobulinemia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176829</classIRI>
<classLabel>Self-Administered Comorbidity Questionnaire</classLabel>
<newAxiom>'Self-Administered Comorbidity Questionnaire' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176828</classIRI>
<classLabel>Medical Expenditure Panel Survey</classLabel>
<newAxiom>'Medical Expenditure Panel Survey' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176827</classIRI>
<classLabel>Severe Congenital Neutropenia Type 1, Autosomal Dominant</classLabel>
<newAxiom>'Severe Congenital Neutropenia Type 1, Autosomal Dominant' SubClassOf 'Autosomal Dominant Severe Congenital Neutropenia'</newAxiom>
<newAxiom>'Severe Congenital Neutropenia Type 1, Autosomal Dominant' SubClassOf 'Disease_Mapped_To_Gene' some 'ELANE Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176826</classIRI>
<classLabel>Ectodermal Dysplasia and Immunodeficiency 2</classLabel>
<newAxiom>'Ectodermal Dysplasia and Immunodeficiency 2' SubClassOf 'Ectodermal Dysplasia and Immunodeficiency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176597</classIRI>
<classLabel>Immunodeficiencies Affecting Cellular and Humoral Immunity - Combined Immune Deficiency</classLabel>
<newAxiom>'Immunodeficiencies Affecting Cellular and Humoral Immunity - Combined Immune Deficiency' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176596</classIRI>
<classLabel>Combined Immunodeficiencies Associated with Syndromic Features</classLabel>
<newAxiom>'Combined Immunodeficiencies Associated with Syndromic Features' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176595</classIRI>
<classLabel>Immune Dysregulation Disorder</classLabel>
<newAxiom>'Immune Dysregulation Disorder' SubClassOf 'Immune System Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176594</classIRI>
<classLabel>Defects in Intrinsic and Innate Immunity</classLabel>
<newAxiom>'Defects in Intrinsic and Innate Immunity' SubClassOf 'Immune System Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176599</classIRI>
<classLabel>Predominantly Antibody Deficiencies</classLabel>
<newAxiom>'Predominantly Antibody Deficiencies' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176598</classIRI>
<classLabel>Immunodeficiencies Affecting Cellular and Humoral Immunity - Severe Combined Immune Deficiency</classLabel>
<newAxiom>'Immunodeficiencies Affecting Cellular and Humoral Immunity - Severe Combined Immune Deficiency' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176586</classIRI>
<classLabel>STING Agonist</classLabel>
<newAxiom>'STING Agonist' SubClassOf 'Antineoplastic Immunomodulating Agent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176585</classIRI>
<classLabel>RNA Component of Mitochondrial RNA Processing Endoribonuclease</classLabel>
<newAxiom>'RNA Component of Mitochondrial RNA Processing Endoribonuclease' SubClassOf 'Gene_Product_Has_Biochemical_Function' some 'Endoribonuclease'</newAxiom>
<newAxiom>'RNA Component of Mitochondrial RNA Processing Endoribonuclease' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Replication'</newAxiom>
<newAxiom>'RNA Component of Mitochondrial RNA Processing Endoribonuclease' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Mitochondrial Matrix'</newAxiom>
<newAxiom>'RNA Component of Mitochondrial RNA Processing Endoribonuclease' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Processing'</newAxiom>
<newAxiom>'RNA Component of Mitochondrial RNA Processing Endoribonuclease' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'RMRP Gene'</newAxiom>
<newAxiom>'RNA Component of Mitochondrial RNA Processing Endoribonuclease' SubClassOf 'LincRNA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176584</classIRI>
<classLabel>RMRP wt Allele</classLabel>
<newAxiom>'RMRP wt Allele' SubClassOf 'RMRP Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176583</classIRI>
<classLabel>RMRP Gene</classLabel>
<newAxiom>'RMRP Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'DNA Replication'</newAxiom>
<newAxiom>'RMRP Gene' SubClassOf 'Endoribonuclease Gene'</newAxiom>
<newAxiom>'RMRP Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Processing'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176589</classIRI>
<classLabel>TTC7A Gene</classLabel>
<newAxiom>'TTC7A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein-Protein Interaction'</newAxiom>
<newAxiom>'TTC7A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Subcellular Protein Targeting'</newAxiom>
<newAxiom>'TTC7A Gene' SubClassOf 'Ligand Binding Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176588</classIRI>
<classLabel>CHEK2-Associated Li-Fraumeni Syndrome</classLabel>
<newAxiom>'CHEK2-Associated Li-Fraumeni Syndrome' EquivalentTo 'Li-Fraumeni Syndrome' and ('Disease_Has_Molecular_Abnormality' some 'CHEK2 Gene Mutation') and ('Disease_May_Have_Associated_Disease' some 'Colorectal Carcinoma') and ('Disease_May_Have_Associated_Disease' some 'Non-Hodgkin Lymphoma') and ('Disease_May_Have_Associated_Disease' some 'Thyroid Gland Carcinoma') and ('Disease_May_Have_Associated_Disease' some 'Prostate Carcinoma') and ('Disease_May_Have_Associated_Disease' some 'Gastric Carcinoma') and ('Disease_May_Have_Associated_Disease' some 'Kidney Carcinoma') and ('Disease_Mapped_To_Gene' some 'CHEK2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176587</classIRI>
<classLabel>TP53-Associated Li-Fraumeni Syndrome</classLabel>
<newAxiom>'TP53-Associated Li-Fraumeni Syndrome' EquivalentTo 'Li-Fraumeni Syndrome' and ('Disease_Has_Molecular_Abnormality' some 'TP53 Gene Mutation') and ('Disease_May_Have_Associated_Disease' some 'Leukemia') and ('Disease_May_Have_Associated_Disease' some 'Medulloblastoma') and ('Disease_May_Have_Associated_Disease' some 'Choroid Plexus Carcinoma') and ('Disease_May_Have_Associated_Disease' some 'Astrocytic Tumor') and ('Disease_May_Have_Associated_Disease' some 'Osteosarcoma') and ('Disease_May_Have_Associated_Disease' some 'Adrenal Cortex Carcinoma') and ('Disease_Mapped_To_Gene' some 'TP53 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176593</classIRI>
<classLabel>Congenital Defects of Phagocyte Number, Function, or Both</classLabel>
<newAxiom>'Congenital Defects of Phagocyte Number, Function, or Both' SubClassOf 'Immune System Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176592</classIRI>
<classLabel>Ectodermal Dysplasia and Immunodeficiency 1</classLabel>
<newAxiom>'Ectodermal Dysplasia and Immunodeficiency 1' SubClassOf 'Ectodermal Dysplasia and Immunodeficiency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176591</classIRI>
<classLabel>Tetratricopeptide Repeat Protein 7A</classLabel>
<newAxiom>'Tetratricopeptide Repeat Protein 7A' EquivalentTo 'Ligand Binding Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Expressed_In_Tissue' some 'Epithelial Tissue') and ('Gene_Product_Has_Biochemical_Function' some 'Scaffolding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Protein Interaction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Subcellular Protein Targeting') and ('Gene_Product_Encoded_By_Gene' some 'TTC7A Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176590</classIRI>
<classLabel>TTC7A wt Allele</classLabel>
<newAxiom>'TTC7A wt Allele' SubClassOf 'TTC7A Gene'</newAxiom>
<newAxiom>'TTC7A wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '2p21'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176575</classIRI>
<classLabel>RFXAP Gene</classLabel>
<newAxiom>'RFXAP Gene' SubClassOf 'Transcription Factor Gene'</newAxiom>
<newAxiom>'RFXAP Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Activation'</newAxiom>
<newAxiom>'RFXAP Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immune System Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176574</classIRI>
<classLabel>DNA-Binding Protein RFXANK</classLabel>
<newAxiom>'DNA-Binding Protein RFXANK' EquivalentTo 'Transcription Factor' and ('Gene_Product_Is_Element_In_Pathway' some 'Antigen Processing and Presentation Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Primary Immunodeficiency Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'HDAC Class II Signaling Pathway') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Ankyrin Repeat') and ('Gene_Product_Is_Physical_Part_Of' some 'Regulatory Factor X Complex') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immune System Process') and ('Gene_Product_Encoded_By_Gene' some 'RFXANK Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176573</classIRI>
<classLabel>Autologous Tolerogenic Proinsulin Peptide-loaded Dendritic Cells PIpepTolDC</classLabel>
<newAxiom>'Autologous Tolerogenic Proinsulin Peptide-loaded Dendritic Cells PIpepTolDC' SubClassOf 'Therapeutic Autologous Dendritic Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176572</classIRI>
<classLabel>RFXANK wt Allele</classLabel>
<newAxiom>'RFXANK wt Allele' EquivalentTo 'RFXANK Gene' and ('Gene_Is_Element_In_Pathway' some 'Antigen Processing and Presentation Pathway') and ('Gene_Is_Element_In_Pathway' some 'Primary Immunodeficiency Pathway') and ('Gene_Is_Element_In_Pathway' some 'HDAC Class II Signaling Pathway') and ('Gene_In_Chromosomal_Location' some '19p13.11')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176579</classIRI>
<classLabel>Invasive Female Breast Carcinoma</classLabel>
<newAxiom>'Invasive Female Breast Carcinoma' EquivalentTo 'Female Breast Carcinoma' and 'Invasive Breast Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176578</classIRI>
<classLabel>IRE1 RNase Inhibitor ORIN1001</classLabel>
<newAxiom>'IRE1 RNase Inhibitor ORIN1001' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176577</classIRI>
<classLabel>Regulatory Factor X-Associated Protein</classLabel>
<newAxiom>'Regulatory Factor X-Associated Protein' EquivalentTo 'Transcription Factor' and ('Gene_Product_Is_Element_In_Pathway' some 'Antigen Processing and Presentation Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Primary Immunodeficiency Pathway') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Nuclear Localization Signal') and ('Gene_Product_Is_Physical_Part_Of' some 'Regulatory Factor X Complex') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immune System Process') and ('Gene_Product_Encoded_By_Gene' some 'RFXAP Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176576</classIRI>
<classLabel>RFXAP wt Allele</classLabel>
<newAxiom>'RFXAP wt Allele' EquivalentTo 'RFXAP Gene' and ('Gene_Is_Element_In_Pathway' some 'Antigen Processing and Presentation Pathway') and ('Gene_Is_Element_In_Pathway' some 'Primary Immunodeficiency Pathway') and ('Gene_In_Chromosomal_Location' some '13q13.3')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176582</classIRI>
<classLabel>Combined Positive Score</classLabel>
<newAxiom>'Combined Positive Score' SubClassOf 'Cell Count'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176581</classIRI>
<classLabel>STING Agonist-containing PTGFRN-expressing Exosomes CDK002</classLabel>
<newAxiom>'STING Agonist-containing PTGFRN-expressing Exosomes CDK002' SubClassOf 'STING Agonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176580</classIRI>
<classLabel>Female Breast Carcinoma In Situ</classLabel>
<newAxiom>'Female Breast Carcinoma In Situ' EquivalentTo 'Female Breast Carcinoma' and 'Stage 0 Breast Cancer AJCC v6 and v7'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176564</classIRI>
<classLabel>Parotid-Sparing Whole-Brain Radiation Therapy</classLabel>
<newAxiom>'Parotid-Sparing Whole-Brain Radiation Therapy' SubClassOf 'Whole-Brain Radiotherapy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176563</classIRI>
<classLabel>CDK7 Inhibitor LY3405105</classLabel>
<newAxiom>'CDK7 Inhibitor LY3405105' SubClassOf 'Chemical_Or_Drug_Has_Mechanism_Of_Action' some 'Enzyme Inhibition'</newAxiom>
<newAxiom>'CDK7 Inhibitor LY3405105' SubClassOf 'Cyclin-Dependent Kinase Inhibitor'</newAxiom>
<newAxiom>'CDK7 Inhibitor LY3405105' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'CDK7 Inhibitor LY3405105' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Negative Regulation of Cell Cycle'</newAxiom>
<newAxiom>'CDK7 Inhibitor LY3405105' SubClassOf 'Chemical_Or_Drug_Affects_Gene_Product' some 'Cyclin-Dependent Kinase'</newAxiom>
<newAxiom>'CDK7 Inhibitor LY3405105' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Positive Regulation of Apoptosis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176562</classIRI>
<classLabel>STING Agonist MK-2118</classLabel>
<newAxiom>'STING Agonist MK-2118' SubClassOf 'STING Agonist'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176561</classIRI>
<classLabel>Phosphoacetylglucosamine Mutase</classLabel>
<newAxiom>'Phosphoacetylglucosamine Mutase' EquivalentTo 'Isomerase' and ('Gene_Product_Is_Element_In_Pathway' some 'Amino and Nucleotide Sugars Metabolism Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytosol') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Glycosylation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Biosynthetic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Carbohydrate Metabolic Process') and ('Gene_Product_Encoded_By_Gene' some 'PGM3 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176568</classIRI>
<classLabel>Autologous Anti-CD22 CAR-expressing T-cells SCRI-CAR22v2</classLabel>
<newAxiom>'Autologous Anti-CD22 CAR-expressing T-cells SCRI-CAR22v2' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
<newAxiom>'Autologous Anti-CD22 CAR-expressing T-cells SCRI-CAR22v2' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous Anti-CD22 CAR-expressing T-cells SCRI-CAR22v2' SubClassOf 'Anti-CD19-targeting CAR-T Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176567</classIRI>
<classLabel>RFX5 wt Allele</classLabel>
<newAxiom>'RFX5 wt Allele' EquivalentTo 'RFX5 Gene' and ('Gene_Is_Element_In_Pathway' some 'Antigen Processing and Presentation Pathway') and ('Gene_Is_Element_In_Pathway' some 'Primary Immunodeficiency Pathway') and ('Gene_In_Chromosomal_Location' some '1q21.3')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176566</classIRI>
<classLabel>RFX5 Gene</classLabel>
<newAxiom>'RFX5 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immune System Process'</newAxiom>
<newAxiom>'RFX5 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Activation'</newAxiom>
<newAxiom>'RFX5 Gene' SubClassOf 'Transcription Factor Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176565</classIRI>
<classLabel>CDK7 Inhibitor LY3405105 Besylate</classLabel>
<newAxiom>'CDK7 Inhibitor LY3405105 Besylate' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Positive Regulation of Apoptosis'</newAxiom>
<newAxiom>'CDK7 Inhibitor LY3405105 Besylate' SubClassOf 'Chemical_Or_Drug_Has_Mechanism_Of_Action' some 'Enzyme Inhibition'</newAxiom>
<newAxiom>'CDK7 Inhibitor LY3405105 Besylate' SubClassOf 'Cyclin-Dependent Kinase Inhibitor'</newAxiom>
<newAxiom>'CDK7 Inhibitor LY3405105 Besylate' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Negative Regulation of Cell Cycle'</newAxiom>
<newAxiom>'CDK7 Inhibitor LY3405105 Besylate' SubClassOf 'Chemical_Or_Drug_Affects_Gene_Product' some 'Cyclin-Dependent Kinase'</newAxiom>
<newAxiom>'CDK7 Inhibitor LY3405105 Besylate' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176569</classIRI>
<classLabel>DNA-Binding Protein RFX5</classLabel>
<newAxiom>'DNA-Binding Protein RFX5' EquivalentTo 'Transcription Factor' and ('Gene_Product_Is_Element_In_Pathway' some 'Antigen Processing and Presentation Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Primary Immunodeficiency Pathway') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Leucine-Rich Repeat') and ('Gene_Product_Is_Physical_Part_Of' some 'Regulatory Factor X Complex') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immune System Process') and ('Gene_Product_Encoded_By_Gene' some 'RFX5 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176571</classIRI>
<classLabel>RFXANK Gene</classLabel>
<newAxiom>'RFXANK Gene' SubClassOf 'Transcription Factor Gene'</newAxiom>
<newAxiom>'RFXANK Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Activation'</newAxiom>
<newAxiom>'RFXANK Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immune System Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176570</classIRI>
<classLabel>Synthetic MVA-based SARS-CoV-2 Vaccine COH04S1</classLabel>
<newAxiom>'Synthetic MVA-based SARS-CoV-2 Vaccine COH04S1' SubClassOf 'COVID-19 Vaccine'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176553</classIRI>
<classLabel>Rate Overall Experience with Communication Related to Cancer Care</classLabel>
<newAxiom>'Rate Overall Experience with Communication Related to Cancer Care' SubClassOf 'Question about Healthcare'</newAxiom>
<newAxiom>'Rate Overall Experience with Communication Related to Cancer Care' SubClassOf 'Communication with Doctor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176552</classIRI>
<classLabel>Was Involved in Making Decisions as Much as Wanted</classLabel>
<newAxiom>'Was Involved in Making Decisions as Much as Wanted' SubClassOf 'Question about Healthcare'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176551</classIRI>
<classLabel>Locally Recurrent Disease</classLabel>
<newAxiom>'Locally Recurrent Disease' SubClassOf 'Recurrent Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176550</classIRI>
<classLabel>Lipopolysaccharide-Responsive and Beige-Like Anchor Protein</classLabel>
<newAxiom>'Lipopolysaccharide-Responsive and Beige-Like Anchor Protein' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'PH Domain'</newAxiom>
<newAxiom>'Lipopolysaccharide-Responsive and Beige-Like Anchor Protein' SubClassOf 'Gene_Product_Has_Associated_Anatomy' some 'Cellular Membrane'</newAxiom>
<newAxiom>'Lipopolysaccharide-Responsive and Beige-Like Anchor Protein' SubClassOf 'Adaptor Signaling Protein'</newAxiom>
<newAxiom>'Lipopolysaccharide-Responsive and Beige-Like Anchor Protein' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Immunologic Factor Process'</newAxiom>
<newAxiom>'Lipopolysaccharide-Responsive and Beige-Like Anchor Protein' SubClassOf 'Gene_Product_Encoded_By_Gene' some 'LRBA Gene'</newAxiom>
<newAxiom>'Lipopolysaccharide-Responsive and Beige-Like Anchor Protein' SubClassOf 'Gene_Product_Has_Structural_Domain_Or_Motif' some 'WD Repeat'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176557</classIRI>
<classLabel>Regulatory Factor X Complex</classLabel>
<newAxiom>'Regulatory Factor X Complex' SubClassOf 'Gene_Product_Has_Biochemical_Function' some 'Transcription Factor'</newAxiom>
<newAxiom>'Regulatory Factor X Complex' SubClassOf 'Protein or Riboprotein Complex'</newAxiom>
<newAxiom>'Regulatory Factor X Complex' SubClassOf 'Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Activation'</newAxiom>
<newAxiom>'Regulatory Factor X Complex' SubClassOf 'Gene_Product_Has_Biochemical_Function' some 'Sequence-Specific DNA Binding Protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176556</classIRI>
<classLabel>Volume-Regulated Anion Channel Subunit LRRC8A</classLabel>
<newAxiom>'Volume-Regulated Anion Channel Subunit LRRC8A' EquivalentTo 'Ion Channel Protein' and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Leucine-Rich Repeat') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cellular Stress Response') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Homeostatic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Osmotic Activity') and ('Gene_Product_Encoded_By_Gene' some 'LRRC8A Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176555</classIRI>
<classLabel>LRRC8A wt Allele</classLabel>
<newAxiom>'LRRC8A wt Allele' SubClassOf 'LRRC8A Gene'</newAxiom>
<newAxiom>'LRRC8A wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '9q34.11'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176554</classIRI>
<classLabel>LRRC8A Gene</classLabel>
<newAxiom>'LRRC8A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cellular Stress Response'</newAxiom>
<newAxiom>'LRRC8A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Osmotic Activity'</newAxiom>
<newAxiom>'LRRC8A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Homeostatic Process'</newAxiom>
<newAxiom>'LRRC8A Gene' SubClassOf 'Ion Channel Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176559</classIRI>
<classLabel>PGM3 Gene</classLabel>
<newAxiom>'PGM3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Carbohydrate Metabolic Process'</newAxiom>
<newAxiom>'PGM3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Biosynthetic Process'</newAxiom>
<newAxiom>'PGM3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Glycosylation'</newAxiom>
<newAxiom>'PGM3 Gene' SubClassOf 'Isomerase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176558</classIRI>
<classLabel>Localized Sarcoma</classLabel>
<newAxiom>'Localized Sarcoma' EquivalentTo 'Localized Malignant Neoplasm' and 'Sarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176560</classIRI>
<classLabel>PGM3 wt Allele</classLabel>
<newAxiom>'PGM3 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Amino and Nucleotide Sugars Metabolism Pathway'</newAxiom>
<newAxiom>'PGM3 wt Allele' SubClassOf 'PGM3 Gene'</newAxiom>
<newAxiom>'PGM3 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '6q14.1'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176542</classIRI>
<classLabel>LRBA Gene</classLabel>
<newAxiom>'LRBA Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immunologic Factor Process'</newAxiom>
<newAxiom>'LRBA Gene' SubClassOf 'Adaptor Signaling Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176541</classIRI>
<classLabel>Knew Who to Contact with a Question or Concern</classLabel>
<newAxiom>'Knew Who to Contact with a Question or Concern' SubClassOf 'Concern Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176540</classIRI>
<classLabel>Got Consistent Information from Doctors and Nurses</classLabel>
<newAxiom>'Got Consistent Information from Doctors and Nurses' SubClassOf 'Information Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176546</classIRI>
<classLabel>LRBA wt Allele</classLabel>
<newAxiom>'LRBA wt Allele' SubClassOf 'LRBA Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176545</classIRI>
<classLabel>Question about Healthcare</classLabel>
<newAxiom>'Question about Healthcare' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176544</classIRI>
<classLabel>Felt Optimism and Hope from Doctors and Nurses</classLabel>
<newAxiom>'Felt Optimism and Hope from Doctors and Nurses' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176543</classIRI>
<classLabel>Felt Comfortable Bringing up Anything on Mind</classLabel>
<newAxiom>'Felt Comfortable Bringing up Anything on Mind' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176549</classIRI>
<classLabel>Knew Who in Healthcare System to Reach Out to if Worried that Something had Gone Wrong with Care</classLabel>
<newAxiom>'Knew Who in Healthcare System to Reach Out to if Worried that Something had Gone Wrong with Care' SubClassOf 'Worry Question'</newAxiom>
<newAxiom>'Knew Who in Healthcare System to Reach Out to if Worried that Something had Gone Wrong with Care' SubClassOf 'Question about Healthcare'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176548</classIRI>
<classLabel>Cancer Care Team Helped with Difficult Feelings</classLabel>
<newAxiom>'Cancer Care Team Helped with Difficult Feelings' SubClassOf 'Question about Healthcare'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176547</classIRI>
<classLabel>Cancer Care Team Helped Coping with Uncertainty or Unknowns</classLabel>
<newAxiom>'Cancer Care Team Helped Coping with Uncertainty or Unknowns' SubClassOf 'Question about Healthcare'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176531</classIRI>
<classLabel>Felt Known as a Person</classLabel>
<newAxiom>'Felt Known as a Person' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176530</classIRI>
<classLabel>Was Treated with Sensitivity and Respect</classLabel>
<newAxiom>'Was Treated with Sensitivity and Respect' SubClassOf 'Treatment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176535</classIRI>
<classLabel>Protein Jagunal Homolog 1</classLabel>
<newAxiom>'Protein Jagunal Homolog 1' EquivalentTo 'Transport Protein' and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Rough Endoplasmic Reticulum') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Smooth Endoplasmic Reticulum') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Exocytosis') and ('Gene_Product_Encoded_By_Gene' some 'JAGN1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176534</classIRI>
<classLabel>Felt Everyone Worked Together as a Team Taking Care of Me</classLabel>
<newAxiom>'Felt Everyone Worked Together as a Team Taking Care of Me' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176533</classIRI>
<classLabel>Felt Comfortable Asking Questions and Voicing Concerns</classLabel>
<newAxiom>'Felt Comfortable Asking Questions and Voicing Concerns' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176532</classIRI>
<classLabel>Felt Listened to</classLabel>
<newAxiom>'Felt Listened to' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176539</classIRI>
<classLabel>Got Clear, Understandable Information</classLabel>
<newAxiom>'Got Clear, Understandable Information' SubClassOf 'Information Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176538</classIRI>
<classLabel>Got Information Needed When Needed</classLabel>
<newAxiom>'Got Information Needed When Needed' SubClassOf 'Information Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176537</classIRI>
<classLabel>Information Question</classLabel>
<newAxiom>'Information Question' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176536</classIRI>
<classLabel>Wishes Were Respected</classLabel>
<newAxiom>'Wishes Were Respected' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176520</classIRI>
<classLabel>HCLS1-Associated Protein X-1</classLabel>
<newAxiom>'HCLS1-Associated Protein X-1' EquivalentTo 'Signaling Protein' and ('Gene_Product_Has_Associated_Anatomy' some 'Cellular Membrane') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Acidic Region') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cytoskeletal Modeling') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Granulopoiesis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cytokine Signaling Process') and ('Gene_Product_Encoded_By_Gene' some 'HAX1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176524</classIRI>
<classLabel>IGHM Gene</classLabel>
<newAxiom>'IGHM Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Humoral Immunity'</newAxiom>
<newAxiom>'IGHM Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Antigen Binding'</newAxiom>
<newAxiom>'IGHM Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immune Response Process'</newAxiom>
<newAxiom>'IGHM Gene' SubClassOf 'Immunoprotein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176523</classIRI>
<classLabel>Heterogeneous Nuclear Ribonucleoprotein H2</classLabel>
<newAxiom>'Heterogeneous Nuclear Ribonucleoprotein H2' EquivalentTo 'RNA Binding Protein' and ('Gene_Product_Has_Chemical_Classification' some 'Ribonucleoprotein') and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleus') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'RNA Recognition Motif') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Processing') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'RNA Binding') and ('Gene_Product_Encoded_By_Gene' some 'HNRNPH2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176522</classIRI>
<classLabel>HNRNPH2 wt Allele</classLabel>
<newAxiom>'HNRNPH2 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some 'Xq22.1'</newAxiom>
<newAxiom>'HNRNPH2 wt Allele' SubClassOf 'HNRNPH2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176521</classIRI>
<classLabel>HNRNPH2 Gene</classLabel>
<newAxiom>'HNRNPH2 Gene' SubClassOf 'Ligand Binding Protein Gene'</newAxiom>
<newAxiom>'HNRNPH2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA-Protein Interaction'</newAxiom>
<newAxiom>'HNRNPH2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'RNA Processing'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176528</classIRI>
<classLabel>Patient Assessment of Cancer Communication Experiences</classLabel>
<newAxiom>'Patient Assessment of Cancer Communication Experiences' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176527</classIRI>
<classLabel>JAGN1 Gene</classLabel>
<newAxiom>'JAGN1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Exocytosis'</newAxiom>
<newAxiom>'JAGN1 Gene' SubClassOf 'Transport Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176526</classIRI>
<classLabel>Immunoglobulin Heavy Constant Mu</classLabel>
<newAxiom>'Immunoglobulin Heavy Constant Mu' EquivalentTo 'Immunoprotein' and ('Gene_Product_Has_Chemical_Classification' some 'Immunoglobulin Family Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Extracellular Space') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Immunoglobulin Constant Region') and ('Gene_Product_Is_Physical_Part_Of' some 'Immunoglobulin Heavy Chain') and ('Gene_Product_Is_Physical_Part_Of' some 'Immunoglobulin') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Humoral Immunity') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Signal Transduction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Antigen Binding') and ('Gene_Product_Encoded_By_Gene' some 'IGHM Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176525</classIRI>
<classLabel>IGHM wt Allele</classLabel>
<newAxiom>'IGHM wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '14q32.33'</newAxiom>
<newAxiom>'IGHM wt Allele' SubClassOf 'IGHM Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176529</classIRI>
<classLabel>JAGN1 wt Allele</classLabel>
<newAxiom>'JAGN1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '3p25.3'</newAxiom>
<newAxiom>'JAGN1 wt Allele' SubClassOf 'JAGN1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176513</classIRI>
<classLabel>Unresectable Sinonasal Squamous Cell Carcinoma</classLabel>
<newAxiom>'Unresectable Sinonasal Squamous Cell Carcinoma' EquivalentTo 'Unresectable Head and Neck Squamous Cell Carcinoma' and 'Sinonasal Squamous Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176512</classIRI>
<classLabel>Zinc Finger Protein Gfi-1</classLabel>
<newAxiom>'Zinc Finger Protein Gfi-1' EquivalentTo 'Transcription Factor' and ('Gene_Product_Expressed_In_Tissue' some 'Hematopoietic Stem Cell') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'C2H2 Zinc Finger') and ('Gene_Product_Has_Biochemical_Function' some 'Transcription Repressor/Corepressor') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Repression') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Hematopoietic Process') and ('Gene_Product_Encoded_By_Gene' some 'GFI1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176511</classIRI>
<classLabel>GFI1 wt Allele</classLabel>
<newAxiom>'GFI1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '1p22.1'</newAxiom>
<newAxiom>'GFI1 wt Allele' SubClassOf 'GFI1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176510</classIRI>
<classLabel>GFI1 Gene</classLabel>
<newAxiom>'GFI1 Gene' SubClassOf 'Transcription Factor Gene'</newAxiom>
<newAxiom>'GFI1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Hematopoietic Process'</newAxiom>
<newAxiom>'GFI1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Repression'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176517</classIRI>
<classLabel>Localized Prostate Carcinoma</classLabel>
<newAxiom>'Localized Prostate Carcinoma' EquivalentTo 'Prostate Carcinoma' and 'Localized Carcinoma'</newAxiom>
<newAxiom>'Localized Prostate Carcinoma' SubClassOf 'Prostate Carcinoma'</newAxiom>
<newAxiom>'Localized Prostate Carcinoma' SubClassOf 'Localized Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176516</classIRI>
<classLabel>Cancerization of Pancreatic Ducts</classLabel>
<newAxiom>'Cancerization of Pancreatic Ducts' SubClassOf 'Morphologic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176515</classIRI>
<classLabel>Vulvar Angiosarcoma</classLabel>
<newAxiom>'Vulvar Angiosarcoma' EquivalentTo 'Soft Tissue Angiosarcoma' and 'Vulvar Sarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176514</classIRI>
<classLabel>Unresectable Nasal Cavity Squamous Cell Carcinoma</classLabel>
<newAxiom>'Unresectable Nasal Cavity Squamous Cell Carcinoma' EquivalentTo 'Unresectable Sinonasal Squamous Cell Carcinoma' and 'Nasal Cavity Squamous Cell Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176519</classIRI>
<classLabel>HAX1 wt Allele</classLabel>
<newAxiom>'HAX1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '1q21.3'</newAxiom>
<newAxiom>'HAX1 wt Allele' SubClassOf 'HAX1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176518</classIRI>
<classLabel>HAX1 Gene</classLabel>
<newAxiom>'HAX1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Granulopoiesis'</newAxiom>
<newAxiom>'HAX1 Gene' SubClassOf 'Signaling Pathway Gene'</newAxiom>
<newAxiom>'HAX1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cytoskeletal Modeling'</newAxiom>
<newAxiom>'HAX1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cytokine Signaling Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176502</classIRI>
<classLabel>Dedicator of Cytokinesis Protein 2</classLabel>
<newAxiom>'Dedicator of Cytokinesis Protein 2' EquivalentTo 'Guanine Nucleotide Exchange Factor' and ('Gene_Product_Is_Element_In_Pathway' some 'Chemokine Signaling Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Leukocyte') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytosol') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'SH3 Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell-Mediated Immunity') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'T-Cell Differentiation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cytoskeletal Modeling') and ('Gene_Product_Encoded_By_Gene' some 'DOCK2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176501</classIRI>
<classLabel>DOCK2 wt Allele</classLabel>
<newAxiom>'DOCK2 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Chemokine Signaling Pathway'</newAxiom>
<newAxiom>'DOCK2 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '5q35.1'</newAxiom>
<newAxiom>'DOCK2 wt Allele' SubClassOf 'DOCK2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176500</classIRI>
<classLabel>DOCK2 Gene</classLabel>
<newAxiom>'DOCK2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cell-Mediated Immunity'</newAxiom>
<newAxiom>'DOCK2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cytoskeletal Modeling'</newAxiom>
<newAxiom>'DOCK2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'T-Cell Differentiation'</newAxiom>
<newAxiom>'DOCK2 Gene' SubClassOf 'Signaling Pathway Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176506</classIRI>
<classLabel>G6PC3 Gene</classLabel>
<newAxiom>'G6PC3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Dephosphorylation'</newAxiom>
<newAxiom>'G6PC3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Carbohydrate Metabolic Process'</newAxiom>
<newAxiom>'G6PC3 Gene' SubClassOf 'Phosphatase Family Gene'</newAxiom>
<newAxiom>'G6PC3 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Gluconeogenic Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176505</classIRI>
<classLabel>Fluorine F 18 W372</classLabel>
<newAxiom>'Fluorine F 18 W372' SubClassOf 'Radioconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176504</classIRI>
<classLabel>Invasive Male Breast Carcinoma</classLabel>
<newAxiom>'Invasive Male Breast Carcinoma' EquivalentTo 'Male Breast Carcinoma' and 'Invasive Breast Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176503</classIRI>
<classLabel>Male Breast Carcinoma In Situ</classLabel>
<newAxiom>'Male Breast Carcinoma In Situ' EquivalentTo 'Stage 0 Breast Cancer AJCC v6 and v7' and 'Male Breast Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176509</classIRI>
<classLabel>CDK4/6 Inhibitor GLR2007</classLabel>
<newAxiom>'CDK4/6 Inhibitor GLR2007' SubClassOf 'Antineoplastic Enzyme Inhibitor'</newAxiom>
<newAxiom>'CDK4/6 Inhibitor GLR2007' SubClassOf 'Cyclin-Dependent Kinase Inhibitor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176508</classIRI>
<classLabel>Glucose-6-Phosphatase 3</classLabel>
<newAxiom>'Glucose-6-Phosphatase 3' EquivalentTo 'Phosphatase' and ('Gene_Product_Is_Element_In_Pathway' some 'Galactose Metabolism Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Glycolysis/Gluconeogenesis Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Starch and Sucrose Metabolism Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Insulin Resistance Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Adipocytokine Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Insulin/Insulin Receptor Signaling Pathway') and ('Gene_Product_Has_Chemical_Classification' some 'Transmembrane Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Rough Endoplasmic Reticulum') and ('Gene_Product_Has_Associated_Anatomy' some 'Membrane of the Smooth Endoplasmic Reticulum') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Carbohydrate Metabolic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Dephosphorylation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Gluconeogenic Process') and ('Gene_Product_Encoded_By_Gene' some 'G6PC3 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176507</classIRI>
<classLabel>G6PC3 wt Allele</classLabel>
<newAxiom>'G6PC3 wt Allele' EquivalentTo 'G6PC3 Gene' and ('Gene_Is_Element_In_Pathway' some 'Galactose Metabolism Pathway') and ('Gene_Is_Element_In_Pathway' some 'Glycolysis/Gluconeogenesis Pathway') and ('Gene_Is_Element_In_Pathway' some 'Starch and Sucrose Metabolism Pathway') and ('Gene_Is_Element_In_Pathway' some 'Insulin Resistance Pathway') and ('Gene_Is_Element_In_Pathway' some 'Adipocytokine Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Insulin/Insulin Receptor Signaling Pathway') and ('Gene_In_Chromosomal_Location' some '17q21.31')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176696</classIRI>
<classLabel>Repeat Expansion Disease</classLabel>
<newAxiom>'Repeat Expansion Disease' SubClassOf 'Genetic Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176695</classIRI>
<classLabel>Predisposition to Viral Infections</classLabel>
<newAxiom>'Predisposition to Viral Infections' SubClassOf 'Immune System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176694</classIRI>
<classLabel>Predisposition to Fungal Infections</classLabel>
<newAxiom>'Predisposition to Fungal Infections' SubClassOf 'Immune System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176693</classIRI>
<classLabel>Predisposition to Bacterial Infections</classLabel>
<newAxiom>'Predisposition to Bacterial Infections' SubClassOf 'Immune System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176699</classIRI>
<classLabel>Moderate Grade Fever</classLabel>
<newAxiom>'Moderate Grade Fever' SubClassOf 'Fever'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176698</classIRI>
<classLabel>High Grade Fever</classLabel>
<newAxiom>'High Grade Fever' SubClassOf 'Fever'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176697</classIRI>
<classLabel>Rectal Large Cell Neuroendocrine Carcinoma</classLabel>
<newAxiom>'Rectal Large Cell Neuroendocrine Carcinoma' EquivalentTo 'Rectal Neuroendocrine Neoplasm' and 'Rectal Carcinoma' and 'Colorectal Large Cell Neuroendocrine Carcinoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176685</classIRI>
<classLabel>Neoplastic Plasma Cells 5 Percent or More of Peripheral Blood White Cells</classLabel>
<newAxiom>'Neoplastic Plasma Cells 5 Percent or More of Peripheral Blood White Cells' SubClassOf 'Atypical Lymphocytes Present in Peripheral Blood'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176684</classIRI>
<classLabel>Minimal Residual Disease Less Than 0.1 Percent</classLabel>
<newAxiom>'Minimal Residual Disease Less Than 0.1 Percent' SubClassOf 'Clinical Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176683</classIRI>
<classLabel>HLA-A*03:01 Positive Cells Present</classLabel>
<newAxiom>'HLA-A*03:01 Positive Cells Present' SubClassOf 'HLA-A3 Positive Cells Present'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176682</classIRI>
<classLabel>Locally Recurrent Head and Neck Squamous Cell Carcinoma</classLabel>
<newAxiom>'Locally Recurrent Head and Neck Squamous Cell Carcinoma' EquivalentTo 'Recurrent Head and Neck Squamous Cell Carcinoma' and 'Locally Recurrent Malignant Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176689</classIRI>
<classLabel>Activating NTRK Family Gene Mutation</classLabel>
<newAxiom>'Activating NTRK Family Gene Mutation' SubClassOf 'NTRK Family Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176688</classIRI>
<classLabel>SARS Coronavirus 2 Negative</classLabel>
<newAxiom>'SARS Coronavirus 2 Negative' SubClassOf 'Negative Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176687</classIRI>
<classLabel>Ki-67 Positive Cells Greater than or Equal to 5 Percent</classLabel>
<newAxiom>'Ki-67 Positive Cells Greater than or Equal to 5 Percent' SubClassOf 'Immunophenotypic Finding'</newAxiom>
<newAxiom>'Ki-67 Positive Cells Greater than or Equal to 5 Percent' SubClassOf 'MKI67 Positive'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176686</classIRI>
<classLabel>Crosslinked Multimeric Type III Procollagen Propeptide</classLabel>
<newAxiom>'Crosslinked Multimeric Type III Procollagen Propeptide' SubClassOf 'Prognostic Marker'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176692</classIRI>
<classLabel>EBV Susceptibility</classLabel>
<newAxiom>'EBV Susceptibility' SubClassOf 'Immune System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176691</classIRI>
<classLabel>Activating MET Exon 14 Skipping Mutation</classLabel>
<newAxiom>'Activating MET Exon 14 Skipping Mutation' SubClassOf 'Activating MET Mutation'</newAxiom>
<newAxiom>'Activating MET Exon 14 Skipping Mutation' SubClassOf 'MET Exon 14 Skipping Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176690</classIRI>
<classLabel>Millisiemens</classLabel>
<newAxiom>'Millisiemens' SubClassOf 'Unit of Electrical Conductance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176674</classIRI>
<classLabel>Inactivating STAT5B Gene Mutation</classLabel>
<newAxiom>'Inactivating STAT5B Gene Mutation' SubClassOf 'STAT5B Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176673</classIRI>
<classLabel>Inactivating STAT1 Gene Mutation</classLabel>
<newAxiom>'Inactivating STAT1 Gene Mutation' SubClassOf 'STAT1 Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176672</classIRI>
<classLabel>STAT1 Gene Mutation</classLabel>
<newAxiom>'STAT1 Gene Mutation' SubClassOf 'Gene Variant'</newAxiom>
<newAxiom>'STAT1 Gene Mutation' SubClassOf 'STAT Family Gene Mutation'</newAxiom>
<newAxiom>'STAT1 Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'STAT1 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176671</classIRI>
<classLabel>Activating JAK1 Gene Mutation</classLabel>
<newAxiom>'Activating JAK1 Gene Mutation' SubClassOf 'JAK1 Gene Mutation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176678</classIRI>
<classLabel>Metastatic Malignant Small Intestinal Neoplasm</classLabel>
<newAxiom>'Metastatic Malignant Small Intestinal Neoplasm' EquivalentTo 'Metastatic Malignant Digestive System Neoplasm' and 'Malignant Small Intestinal Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176677</classIRI>
<classLabel>PQ/CMC Units of Measure Terminology</classLabel>
<newAxiom>'PQ/CMC Units of Measure Terminology' SubClassOf 'FDA Pharmaceutical Quality/CMC Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176676</classIRI>
<classLabel>PQ/CMC Excipient Function Terminology</classLabel>
<newAxiom>'PQ/CMC Excipient Function Terminology' SubClassOf 'FDA Pharmaceutical Quality/CMC Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176675</classIRI>
<classLabel>PQ/CMC Drug Product Component Function Category Terminology</classLabel>
<newAxiom>'PQ/CMC Drug Product Component Function Category Terminology' SubClassOf 'FDA Pharmaceutical Quality/CMC Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176679</classIRI>
<classLabel>Advanced Malignant Small Intestinal Neoplasm</classLabel>
<newAxiom>'Advanced Malignant Small Intestinal Neoplasm' EquivalentTo 'Advanced Malignant Digestive System Neoplasm' and 'Metastatic Malignant Small Intestinal Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176681</classIRI>
<classLabel>Refractory Breast Implant-Associated Anaplastic Large Cell Lymphoma</classLabel>
<newAxiom>'Refractory Breast Implant-Associated Anaplastic Large Cell Lymphoma' EquivalentTo 'Refractory Breast Lymphoma' and 'Breast Implant-Associated Anaplastic Large Cell Lymphoma' and 'Refractory Aggressive Non-Hodgkin Lymphoma' and 'Refractory Anaplastic Large Cell Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176680</classIRI>
<classLabel>Recurrent Breast Implant-Associated Anaplastic Large Cell Lymphoma</classLabel>
<newAxiom>'Recurrent Breast Implant-Associated Anaplastic Large Cell Lymphoma' EquivalentTo 'Recurrent Breast Lymphoma' and 'Breast Implant-Associated Anaplastic Large Cell Lymphoma' and 'Recurrent Aggressive Non-Hodgkin Lymphoma' and 'Recurrent Anaplastic Large Cell Lymphoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176663</classIRI>
<classLabel>Suppository Base</classLabel>
<newAxiom>'Suppository Base' SubClassOf 'Drug Vehicle'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176662</classIRI>
<classLabel>Release Modifying Excipient</classLabel>
<newAxiom>'Release Modifying Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176661</classIRI>
<classLabel>Propellant</classLabel>
<newAxiom>'Propellant' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176660</classIRI>
<classLabel>Ophthalmic Polymer</classLabel>
<newAxiom>'Ophthalmic Polymer' SubClassOf 'Polymer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176667</classIRI>
<classLabel>Water Repelling Excipient</classLabel>
<newAxiom>'Water Repelling Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176666</classIRI>
<classLabel>Viscosity Modifying Excipient</classLabel>
<newAxiom>'Viscosity Modifying Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176665</classIRI>
<classLabel>Transfer Ligand Excipient</classLabel>
<newAxiom>'Transfer Ligand Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176664</classIRI>
<classLabel>Transdermal Delivery Excipient</classLabel>
<newAxiom>'Transdermal Delivery Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176669</classIRI>
<classLabel>Immunodeficiency due to Functional Defects</classLabel>
<newAxiom>'Immunodeficiency due to Functional Defects' SubClassOf 'Immunodeficiency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176668</classIRI>
<classLabel>Wetting Excipient</classLabel>
<newAxiom>'Wetting Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176670</classIRI>
<classLabel>Immunodeficiency due to Quantitative Defects</classLabel>
<newAxiom>'Immunodeficiency due to Quantitative Defects' SubClassOf 'Immunodeficiency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176652</classIRI>
<classLabel>Lyophilization Excipient</classLabel>
<newAxiom>'Lyophilization Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176651</classIRI>
<classLabel>Humectant Excipient</classLabel>
<newAxiom>'Humectant Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176650</classIRI>
<classLabel>Gelling Excipient</classLabel>
<newAxiom>'Gelling Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176656</classIRI>
<classLabel>Opacifying Excipient</classLabel>
<newAxiom>'Opacifying Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176655</classIRI>
<classLabel>Ointment Base</classLabel>
<newAxiom>'Ointment Base' SubClassOf 'Drug Vehicle'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176654</classIRI>
<classLabel>Microencapsulating Excipient</classLabel>
<newAxiom>'Microencapsulating Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176653</classIRI>
<classLabel>Matrix Forming Excipient</classLabel>
<newAxiom>'Matrix Forming Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176659</classIRI>
<classLabel>Polishing Excipient</classLabel>
<newAxiom>'Polishing Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176658</classIRI>
<classLabel>pH Modifying Excipient</classLabel>
<newAxiom>'pH Modifying Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176657</classIRI>
<classLabel>Osmotic Excipient</classLabel>
<newAxiom>'Osmotic Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176641</classIRI>
<classLabel>Tonicity Excipient</classLabel>
<newAxiom>'Tonicity Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176640</classIRI>
<classLabel>Solubilizing Excipient</classLabel>
<newAxiom>'Solubilizing Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176645</classIRI>
<classLabel>Carrier Excipient</classLabel>
<newAxiom>'Carrier Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176644</classIRI>
<classLabel>Bulking Excipient</classLabel>
<newAxiom>'Bulking Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176643</classIRI>
<classLabel>Air Displacement Agent</classLabel>
<newAxiom>'Air Displacement Agent' SubClassOf 'Industrial Aid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176642</classIRI>
<classLabel>Adsorbent</classLabel>
<newAxiom>'Adsorbent' SubClassOf 'Reagent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176649</classIRI>
<classLabel>Free Radical Scavenging Excipient</classLabel>
<newAxiom>'Free Radical Scavenging Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176648</classIRI>
<classLabel>Film Coating Excipient</classLabel>
<newAxiom>'Film Coating Excipient' SubClassOf 'Coating Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176647</classIRI>
<classLabel>Denaturant</classLabel>
<newAxiom>'Denaturant' SubClassOf 'Reagent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176646</classIRI>
<classLabel>Complexing Excipient</classLabel>
<newAxiom>'Complexing Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176630</classIRI>
<classLabel>Immunodeficiency 11B with Atopic Dermatitis</classLabel>
<newAxiom>'Immunodeficiency 11B with Atopic Dermatitis' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176634</classIRI>
<classLabel>Foam Stabilizing Excipient</classLabel>
<newAxiom>'Foam Stabilizing Excipient' SubClassOf 'Stabilizing Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176633</classIRI>
<classLabel>Emulsion Stabilizing Excipient</classLabel>
<newAxiom>'Emulsion Stabilizing Excipient' SubClassOf 'Stabilizing Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176632</classIRI>
<classLabel>Emollient Excipient</classLabel>
<newAxiom>'Emollient Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176631</classIRI>
<classLabel>PIK3R1 Deficiency</classLabel>
<newAxiom>'PIK3R1 Deficiency' SubClassOf 'Rare Non-Neoplastic Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176638</classIRI>
<classLabel>Effervescent Excipient</classLabel>
<newAxiom>'Effervescent Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176637</classIRI>
<classLabel>Absorption Modifying Excipient</classLabel>
<newAxiom>'Absorption Modifying Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176636</classIRI>
<classLabel>Stabilizing Excipient</classLabel>
<newAxiom>'Stabilizing Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176635</classIRI>
<classLabel>Organoleptic Excipient</classLabel>
<newAxiom>'Organoleptic Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176639</classIRI>
<classLabel>Reducing Excipient</classLabel>
<newAxiom>'Reducing Excipient' SubClassOf 'Pharmaceutical Excipient'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176623</classIRI>
<classLabel>iPSC-derived CD16/IL-15RF-expressing CD38-eliminated NK Cells FT538</classLabel>
<newAxiom>'iPSC-derived CD16/IL-15RF-expressing CD38-eliminated NK Cells FT538' SubClassOf 'Therapeutic Allogeneic Lymphocytes'</newAxiom>
<newAxiom>'iPSC-derived CD16/IL-15RF-expressing CD38-eliminated NK Cells FT538' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176622</classIRI>
<classLabel>Gastrointestinal Defects And Immunodeficiency Syndrome</classLabel>
<newAxiom>'Gastrointestinal Defects And Immunodeficiency Syndrome' SubClassOf 'Rare Non-Neoplastic Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176621</classIRI>
<classLabel>Zinc Finger Protein 341</classLabel>
<newAxiom>'Zinc Finger Protein 341' EquivalentTo 'Transcription Factor' and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'C2H2 Zinc Finger') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Proline-Rich Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immunoregulation') and ('Gene_Product_Encoded_By_Gene' some 'ZNF341 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176620</classIRI>
<classLabel>ZNF341 wt Allele</classLabel>
<newAxiom>'ZNF341 wt Allele' SubClassOf 'ZNF341 Gene'</newAxiom>
<newAxiom>'ZNF341 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '20q11.22'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176627</classIRI>
<classLabel>Actinium Ac 225-DOTA-h11B6 JNJ-69086420</classLabel>
<newAxiom>'Actinium Ac 225-DOTA-h11B6 JNJ-69086420' SubClassOf 'Radioimmunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176626</classIRI>
<classLabel>Focused Ultrasound Mesencephalotomy</classLabel>
<newAxiom>'Focused Ultrasound Mesencephalotomy' SubClassOf 'Brain Surgery'</newAxiom>
<newAxiom>'Focused Ultrasound Mesencephalotomy' SubClassOf 'High-Intensity Focused Ultrasound Ablation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176625</classIRI>
<classLabel>Anti-DR5 Agonistic Monoclonal Antibody IGM-8444</classLabel>
<newAxiom>'Anti-DR5 Agonistic Monoclonal Antibody IGM-8444' SubClassOf 'Anti-DR5 Monoclonal Antibody'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176624</classIRI>
<classLabel>Autosomal Recessive Severe Congenital Neutropenia</classLabel>
<newAxiom>'Autosomal Recessive Severe Congenital Neutropenia' SubClassOf 'Severe Congenital Neutropenia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176629</classIRI>
<classLabel>Peppermint Oil-containing Enteric-coated Microspheres</classLabel>
<newAxiom>'Peppermint Oil-containing Enteric-coated Microspheres' SubClassOf 'Agent Affecting Digestive System or Metabolism'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176628</classIRI>
<classLabel>CDH1-Associated Breast Carcinoma Syndrome</classLabel>
<newAxiom>'CDH1-Associated Breast Carcinoma Syndrome' EquivalentTo 'Hereditary Neoplastic Syndrome' and ('Disease_Has_Molecular_Abnormality' some 'CDH1 Gene Inactivation') and ('Disease_May_Have_Associated_Disease' some 'Breast Lobular Carcinoma') and ('Disease_Mapped_To_Gene' some 'CDH1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176612</classIRI>
<classLabel>Severe Congenital Neutropenia Type 5, Autosomal Recessive</classLabel>
<newAxiom>'Severe Congenital Neutropenia Type 5, Autosomal Recessive' SubClassOf 'Autosomal Recessive Severe Congenital Neutropenia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176611</classIRI>
<classLabel>Severe Congenital Neutropenia Type 4, Autosomal Recessive</classLabel>
<newAxiom>'Severe Congenital Neutropenia Type 4, Autosomal Recessive' SubClassOf 'Autosomal Recessive Severe Congenital Neutropenia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176610</classIRI>
<classLabel>Severe Congenital Neutropenia Type 2, Autosomal Dominant</classLabel>
<newAxiom>'Severe Congenital Neutropenia Type 2, Autosomal Dominant' SubClassOf 'Autosomal Dominant Severe Congenital Neutropenia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176616</classIRI>
<classLabel>WAS/WASL-Interacting Protein Family Member 1</classLabel>
<newAxiom>'WAS/WASL-Interacting Protein Family Member 1' EquivalentTo 'Cytoskeletal Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Endocytosis Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Pathogenic Escherichia coli Infection Pathway') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Proline-Rich Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Actin-Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Protein Interaction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cytoskeletal Modeling') and ('Gene_Product_Encoded_By_Gene' some 'WIPF1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176615</classIRI>
<classLabel>WIPF1 wt Allele</classLabel>
<newAxiom>'WIPF1 wt Allele' EquivalentTo 'WIPF1 Gene' and ('Gene_Is_Element_In_Pathway' some 'Endocytosis Pathway') and ('Gene_Is_Element_In_Pathway' some 'Pathogenic Escherichia coli Infection Pathway') and ('Gene_In_Chromosomal_Location' some '2q31.1')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176614</classIRI>
<classLabel>Severe Congenital Neutropenia Type 7, Autosomal Recessive</classLabel>
<newAxiom>'Severe Congenital Neutropenia Type 7, Autosomal Recessive' SubClassOf 'Autosomal Recessive Severe Congenital Neutropenia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176613</classIRI>
<classLabel>WIPF1 Gene</classLabel>
<newAxiom>'WIPF1 Gene' SubClassOf 'Cytoskeletal Gene'</newAxiom>
<newAxiom>'WIPF1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cytoskeletal Modeling'</newAxiom>
<newAxiom>'WIPF1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein-Protein Interaction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176619</classIRI>
<classLabel>Proteasome-Associated Autoinflammatory Syndrome 1</classLabel>
<newAxiom>'Proteasome-Associated Autoinflammatory Syndrome 1' SubClassOf 'Disease_Mapped_To_Gene' some 'PSMB8 Gene'</newAxiom>
<newAxiom>'Proteasome-Associated Autoinflammatory Syndrome 1' SubClassOf 'Autoinflammatory Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176618</classIRI>
<classLabel>ZNF341 Gene</classLabel>
<newAxiom>'ZNF341 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Activation'</newAxiom>
<newAxiom>'ZNF341 Gene' SubClassOf 'Transcription Factor Gene'</newAxiom>
<newAxiom>'ZNF341 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immunoregulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176617</classIRI>
<classLabel>Thrombocytopenia 1</classLabel>
<newAxiom>'Thrombocytopenia 1' SubClassOf 'Congenital Hematological Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176601</classIRI>
<classLabel>Mendelian Susceptibility to Mycobacterial Diseases</classLabel>
<newAxiom>'Mendelian Susceptibility to Mycobacterial Diseases' SubClassOf 'Rare Non-Neoplastic Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176600</classIRI>
<classLabel>Primary Immune Regulatory Disorder</classLabel>
<newAxiom>'Primary Immune Regulatory Disorder' SubClassOf 'Immune System Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176605</classIRI>
<classLabel>Severe Combined Immunodeficiency due to CD45 Deficiency</classLabel>
<newAxiom>'Severe Combined Immunodeficiency due to CD45 Deficiency' SubClassOf 'Severe Combined Immunodeficiency, Autosomal Recessive, T-Cell Negative, B Cell-Positive, NK Cell-Positive'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176604</classIRI>
<classLabel>VPS45 wt Allele</classLabel>
<newAxiom>'VPS45 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Endocytosis Pathway'</newAxiom>
<newAxiom>'VPS45 wt Allele' SubClassOf 'VPS45 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176603</classIRI>
<classLabel>VPS45 Gene</classLabel>
<newAxiom>'VPS45 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Subcellular Protein Targeting'</newAxiom>
<newAxiom>'VPS45 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Endocytotic Process'</newAxiom>
<newAxiom>'VPS45 Gene' SubClassOf 'Trafficking Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176602</classIRI>
<classLabel>Severe Congenital Neutropenia Type 6, Autosomal Recessive</classLabel>
<newAxiom>'Severe Congenital Neutropenia Type 6, Autosomal Recessive' SubClassOf 'Autosomal Recessive Severe Congenital Neutropenia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176609</classIRI>
<classLabel>Vacuolar Protein Sorting-Associated Protein 45</classLabel>
<newAxiom>'Vacuolar Protein Sorting-Associated Protein 45' EquivalentTo 'Transport Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Endocytosis Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Golgi Apparatus') and ('Gene_Product_Has_Associated_Anatomy' some 'Endosome') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein-Protein Interaction') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Subcellular Protein Targeting') and ('Gene_Product_Encoded_By_Gene' some 'VPS45 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176608</classIRI>
<classLabel>Epidermodysplasia Verruciformis, Susceptibility to, 4</classLabel>
<newAxiom>'Epidermodysplasia Verruciformis, Susceptibility to, 4' SubClassOf 'Immunodeficiency Syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176607</classIRI>
<classLabel>Severe Combined Immunodeficiency due to RAG2 Deficiency</classLabel>
<newAxiom>'Severe Combined Immunodeficiency due to RAG2 Deficiency' SubClassOf 'Severe Combined Immunodeficiency with Absence of T and B Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176606</classIRI>
<classLabel>Severe Combined Immunodeficiency due to RAG1 Deficiency</classLabel>
<newAxiom>'Severe Combined Immunodeficiency due to RAG1 Deficiency' SubClassOf 'Severe Combined Immunodeficiency with Absence of T and B Cells'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176377</classIRI>
<classLabel>Picogram Per Cell</classLabel>
<newAxiom>'Picogram Per Cell' SubClassOf 'Unit of Mass'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176376</classIRI>
<classLabel>Study Contact Postal Address</classLabel>
<newAxiom>'Study Contact Postal Address' SubClassOf 'Postal Address'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176375</classIRI>
<classLabel>Study Contact E-mail Address</classLabel>
<newAxiom>'Study Contact E-mail Address' SubClassOf 'E-mail Address'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176374</classIRI>
<classLabel>Study Contact Telephone Number</classLabel>
<newAxiom>'Study Contact Telephone Number' SubClassOf 'Telephone Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176379</classIRI>
<classLabel>Nanomole per Kilogram per Day</classLabel>
<newAxiom>'Nanomole per Kilogram per Day' SubClassOf 'Unit of Dose Calculation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176378</classIRI>
<classLabel>Gram per Liter per Day</classLabel>
<newAxiom>'Gram per Liter per Day' SubClassOf 'Unit of Dose Calculation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176380</classIRI>
<classLabel>Hour per Day</classLabel>
<newAxiom>'Hour per Day' SubClassOf 'Unit of Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176384</classIRI>
<classLabel>European Pharmacopoeia Unit</classLabel>
<newAxiom>'European Pharmacopoeia Unit' SubClassOf 'Potency Unit'</newAxiom>
<newAxiom>'European Pharmacopoeia Unit' SubClassOf 'Unit of Biological and Biochemical Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176383</classIRI>
<classLabel>Nanokatal per Gram Hemoglobin</classLabel>
<newAxiom>'Nanokatal per Gram Hemoglobin' SubClassOf 'Unit of Catalytic Activity Concentration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176382</classIRI>
<classLabel>Breaths per Thirty Seconds</classLabel>
<newAxiom>'Breaths per Thirty Seconds' SubClassOf 'Units for Vital Signs Results'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176381</classIRI>
<classLabel>Minute per Day</classLabel>
<newAxiom>'Minute per Day' SubClassOf 'Unit of Time'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176366</classIRI>
<classLabel>Basal Tear</classLabel>
<newAxiom>'Basal Tear' SubClassOf 'Tear'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176365</classIRI>
<classLabel>Country of Permanent Address</classLabel>
<newAxiom>'Country of Permanent Address' SubClassOf 'Country'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176364</classIRI>
<classLabel>Village of Permanent Address</classLabel>
<newAxiom>'Village of Permanent Address' SubClassOf 'Village'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176363</classIRI>
<classLabel>District of Permanent Address</classLabel>
<newAxiom>'District of Permanent Address' SubClassOf 'District'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176369</classIRI>
<classLabel>Arterialized Capillary Blood</classLabel>
<newAxiom>'Arterialized Capillary Blood' SubClassOf 'Capillary Blood'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176368</classIRI>
<classLabel>Emotional Tear</classLabel>
<newAxiom>'Emotional Tear' SubClassOf 'Tear'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176367</classIRI>
<classLabel>Reflex Tear</classLabel>
<newAxiom>'Reflex Tear' SubClassOf 'Tear'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176373</classIRI>
<classLabel>Study Contact Name</classLabel>
<newAxiom>'Study Contact Name' SubClassOf 'Contact Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176372</classIRI>
<classLabel>Study Contact Role</classLabel>
<newAxiom>'Study Contact Role' SubClassOf 'Clinical Study Functional Role'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176371</classIRI>
<classLabel>Endometrial Tissue</classLabel>
<newAxiom>'Endometrial Tissue' SubClassOf 'Simple Columnar Epithelium'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176370</classIRI>
<classLabel>Plasma Ultrafiltrate</classLabel>
<newAxiom>'Plasma Ultrafiltrate' SubClassOf 'Plasma Product'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176355</classIRI>
<classLabel>Dosing Interval</classLabel>
<newAxiom>'Dosing Interval' SubClassOf 'Interval'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176354</classIRI>
<classLabel>Ratio Amount Recovered Infinity Observed</classLabel>
<newAxiom>'Ratio Amount Recovered Infinity Observed' SubClassOf 'Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176353</classIRI>
<classLabel>Ratio Concentration Trough</classLabel>
<newAxiom>'Ratio Concentration Trough' SubClassOf 'Concentration Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176352</classIRI>
<classLabel>Ratio Maximum Concentration Normalized by Dose</classLabel>
<newAxiom>'Ratio Maximum Concentration Normalized by Dose' SubClassOf 'Concentration Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176359</classIRI>
<classLabel>Vaginal Bleeding and/or Spotting Frequency Description</classLabel>
<newAxiom>'Vaginal Bleeding and/or Spotting Frequency Description' SubClassOf 'Description'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176358</classIRI>
<classLabel>Declined To Continue Into Survival Follow-Up</classLabel>
<newAxiom>'Declined To Continue Into Survival Follow-Up' SubClassOf 'Subject Decision'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176357</classIRI>
<classLabel>Opted To Continue Into Survival Follow-Up</classLabel>
<newAxiom>'Opted To Continue Into Survival Follow-Up' SubClassOf 'Subject Decision'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176356</classIRI>
<classLabel>Hour Times Microgram Per Gram</classLabel>
<newAxiom>'Hour Times Microgram Per Gram' SubClassOf 'Measurement Unit Description'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176362</classIRI>
<classLabel>County of Permanent Address</classLabel>
<newAxiom>'County of Permanent Address' SubClassOf 'County'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176361</classIRI>
<classLabel>Term Pregnancy Category</classLabel>
<newAxiom>'Term Pregnancy Category' SubClassOf 'Pregnancy Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176360</classIRI>
<classLabel>Hospitalized Due to Pregnancy Complication Indicator</classLabel>
<newAxiom>'Hospitalized Due to Pregnancy Complication Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176344</classIRI>
<classLabel>AUC All Ratio</classLabel>
<newAxiom>'AUC All Ratio' SubClassOf 'Area Under the Curve Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176343</classIRI>
<classLabel>Logistical Problem With Clinical Study</classLabel>
<newAxiom>'Logistical Problem With Clinical Study' SubClassOf 'Problem'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176342</classIRI>
<classLabel>Study Consent Withdrawn</classLabel>
<newAxiom>'Study Consent Withdrawn' SubClassOf 'Consent Withdrawn'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176341</classIRI>
<classLabel>Lymphocyte Function-Associated Antigen 1 Measurement</classLabel>
<newAxiom>'Lymphocyte Function-Associated Antigen 1 Measurement' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176348</classIRI>
<classLabel>Ratio AUC Infinity Observed Normalized by Dose</classLabel>
<newAxiom>'Ratio AUC Infinity Observed Normalized by Dose' SubClassOf 'Area Under the Curve Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176347</classIRI>
<classLabel>Ratio Amount Recovered from T1 to T2</classLabel>
<newAxiom>'Ratio Amount Recovered from T1 to T2' SubClassOf 'Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176346</classIRI>
<classLabel>Minimum Concentration Ratio</classLabel>
<newAxiom>'Minimum Concentration Ratio' SubClassOf 'Concentration Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176345</classIRI>
<classLabel>Average Concentration Ratio</classLabel>
<newAxiom>'Average Concentration Ratio' SubClassOf 'Concentration Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176349</classIRI>
<classLabel>Ratio AUC from T1 to T2 Normalized by Dose</classLabel>
<newAxiom>'Ratio AUC from T1 to T2 Normalized by Dose' SubClassOf 'Ratio AUC From T1 to T2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176351</classIRI>
<classLabel>Ratio AUC Over Dosing Interval</classLabel>
<newAxiom>'Ratio AUC Over Dosing Interval' SubClassOf 'Area Under the Curve Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176350</classIRI>
<classLabel>Ratio AUC to Last Nonzero Concentration Normalized by Dose</classLabel>
<newAxiom>'Ratio AUC to Last Nonzero Concentration Normalized by Dose' SubClassOf 'Ratio AUC to Last Nonzero Concentration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176333</classIRI>
<classLabel>Ulceration Assessment</classLabel>
<newAxiom>'Ulceration Assessment' SubClassOf 'Anatomic Pathology Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176332</classIRI>
<classLabel>Indirect Immunofluorescence</classLabel>
<newAxiom>'Indirect Immunofluorescence' SubClassOf 'Fluorescent Antibody Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176331</classIRI>
<classLabel>Magnetic Resonance Enterography</classLabel>
<newAxiom>'Magnetic Resonance Enterography' SubClassOf 'Magnetic Resonance Imaging'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176330</classIRI>
<classLabel>Autorefraction</classLabel>
<newAxiom>'Autorefraction' SubClassOf 'Eye Examination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176337</classIRI>
<classLabel>Crypt Architectural Damage Assessment</classLabel>
<newAxiom>'Crypt Architectural Damage Assessment' SubClassOf 'Anatomic Pathology Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176336</classIRI>
<classLabel>Crypt Abscess Assessment</classLabel>
<newAxiom>'Crypt Abscess Assessment' SubClassOf 'Anatomic Pathology Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176335</classIRI>
<classLabel>Cryptitis Assessment</classLabel>
<newAxiom>'Cryptitis Assessment' SubClassOf 'Anatomic Pathology Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176334</classIRI>
<classLabel>Granuloma Assessment</classLabel>
<newAxiom>'Granuloma Assessment' SubClassOf 'Anatomic Pathology Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176339</classIRI>
<classLabel>Paneth Cell Metaplasia Assessment</classLabel>
<newAxiom>'Paneth Cell Metaplasia Assessment' SubClassOf 'Anatomic Pathology Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176338</classIRI>
<classLabel>Epithelial Integrity Assessment</classLabel>
<newAxiom>'Epithelial Integrity Assessment' SubClassOf 'Anatomic Pathology Procedure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176340</classIRI>
<classLabel>Number of Abnormal Tissue Samples</classLabel>
<newAxiom>'Number of Abnormal Tissue Samples' SubClassOf 'Total Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176322</classIRI>
<classLabel>Atrioventricular Valve</classLabel>
<newAxiom>'Atrioventricular Valve' SubClassOf 'Cardiac Valve'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176321</classIRI>
<classLabel>Fore Limb</classLabel>
<newAxiom>'Fore Limb' SubClassOf 'Experimental Organism Anatomical Concept'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176320</classIRI>
<classLabel>Sternebra</classLabel>
<newAxiom>'Sternebra' SubClassOf 'Flat Bone'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176326</classIRI>
<classLabel>Fat Pad</classLabel>
<newAxiom>'Fat Pad' SubClassOf 'Adipose Tissue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176325</classIRI>
<classLabel>Eye Bulge</classLabel>
<newAxiom>'Eye Bulge' SubClassOf 'Eye Part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176324</classIRI>
<classLabel>Genital Tubercle</classLabel>
<newAxiom>'Genital Tubercle' SubClassOf 'Embryonic Tissue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176323</classIRI>
<classLabel>Claw</classLabel>
<newAxiom>'Claw' SubClassOf 'Appendage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176329</classIRI>
<classLabel>Sodium Lauryl Sulphate Method</classLabel>
<newAxiom>'Sodium Lauryl Sulphate Method' SubClassOf 'Protein Analysis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176328</classIRI>
<classLabel>Sheath Flow Direct Current Detection</classLabel>
<newAxiom>'Sheath Flow Direct Current Detection' SubClassOf 'Flow Cytometry'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176327</classIRI>
<classLabel>SARS-CoV-2 Antigen Measurement</classLabel>
<newAxiom>'SARS-CoV-2 Antigen Measurement' SubClassOf 'Immunology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176311</classIRI>
<classLabel>Coefficient of Fat Absorption Measurement</classLabel>
<newAxiom>'Coefficient of Fat Absorption Measurement' SubClassOf 'Chemistry Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176310</classIRI>
<classLabel>Coefficient of Nitrogen Absorption Measurement</classLabel>
<newAxiom>'Coefficient of Nitrogen Absorption Measurement' SubClassOf 'Chemistry Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176315</classIRI>
<classLabel>Colon Wall</classLabel>
<newAxiom>'Colon Wall' SubClassOf 'Lower Gastrointestinal Tract Wall'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176314</classIRI>
<classLabel>Upper Gastrointestinal Tract Wall</classLabel>
<newAxiom>'Upper Gastrointestinal Tract Wall' SubClassOf 'Gastrointestinal Tract Wall'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176313</classIRI>
<classLabel>Anti-Neutrophil Antibody Measurement</classLabel>
<newAxiom>'Anti-Neutrophil Antibody Measurement' SubClassOf 'Immunology Test'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176312</classIRI>
<classLabel>Phosphorylated Tau Protein to Amyloid Beta1-42 Ratio Measurement</classLabel>
<newAxiom>'Phosphorylated Tau Protein to Amyloid Beta1-42 Ratio Measurement' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176319</classIRI>
<classLabel>Caudal Vertebra</classLabel>
<newAxiom>'Caudal Vertebra' SubClassOf 'Vertebra'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176318</classIRI>
<classLabel>Ileum Lymph Node</classLabel>
<newAxiom>'Ileum Lymph Node' SubClassOf 'Lower Gastrointestinal Tract Lymph Node'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176317</classIRI>
<classLabel>Colon Lymph Node</classLabel>
<newAxiom>'Colon Lymph Node' SubClassOf 'Lower Gastrointestinal Tract Lymph Node'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176316</classIRI>
<classLabel>Ileum Wall</classLabel>
<newAxiom>'Ileum Wall' SubClassOf 'Lower Gastrointestinal Tract Wall'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176300</classIRI>
<classLabel>Hyocholate Measurement</classLabel>
<newAxiom>'Hyocholate Measurement' SubClassOf 'Cholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176304</classIRI>
<classLabel>Epimerized Ursodeoxycholate Measurement</classLabel>
<newAxiom>'Epimerized Ursodeoxycholate Measurement' SubClassOf 'Ursodeoxycholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176303</classIRI>
<classLabel>Tauroursodeoxycholate Measurement</classLabel>
<newAxiom>'Tauroursodeoxycholate Measurement' SubClassOf 'Ursodeoxycholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176302</classIRI>
<classLabel>Glycoursodeoxycholate Measurement</classLabel>
<newAxiom>'Glycoursodeoxycholate Measurement' SubClassOf 'Ursodeoxycholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176301</classIRI>
<classLabel>Taurocholate Measurement</classLabel>
<newAxiom>'Taurocholate Measurement' SubClassOf 'Cholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176308</classIRI>
<classLabel>Glycolithocholate Measurement</classLabel>
<newAxiom>'Glycolithocholate Measurement' SubClassOf 'Lithocholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176307</classIRI>
<classLabel>Lithocholate Measurement</classLabel>
<newAxiom>'Lithocholate Measurement' SubClassOf 'Lithocholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176306</classIRI>
<classLabel>Taurochenodeoxycholate Measurement</classLabel>
<newAxiom>'Taurochenodeoxycholate Measurement' SubClassOf 'Chenodeoxycholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176305</classIRI>
<classLabel>Glycochenodeoxycholate Measurement</classLabel>
<newAxiom>'Glycochenodeoxycholate Measurement' SubClassOf 'Chenodeoxycholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176309</classIRI>
<classLabel>Taurolithocholate Measurement</classLabel>
<newAxiom>'Taurolithocholate Measurement' SubClassOf 'Lithocholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176399</classIRI>
<classLabel>Increased Apoptosis</classLabel>
<newAxiom>'Increased Apoptosis' SubClassOf 'Morphologic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176398</classIRI>
<classLabel>Increased Cellular Aggregates</classLabel>
<newAxiom>'Increased Cellular Aggregates' SubClassOf 'Morphologic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176397</classIRI>
<classLabel>Renaut Body</classLabel>
<newAxiom>'Renaut Body' SubClassOf 'Morphologic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176396</classIRI>
<classLabel>Neuronal Autophagy</classLabel>
<newAxiom>'Neuronal Autophagy' SubClassOf 'Autophagy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176388</classIRI>
<classLabel>Megabase Pair</classLabel>
<newAxiom>'Megabase Pair' SubClassOf 'Base Pair Unit'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176387</classIRI>
<classLabel>Per Megabase Pair</classLabel>
<newAxiom>'Per Megabase Pair' SubClassOf 'Base Pair Unit'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176386</classIRI>
<classLabel>Nanogram per Mole</classLabel>
<newAxiom>'Nanogram per Mole' SubClassOf 'Unit of Dose Calculation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176385</classIRI>
<classLabel>Microgram per Mole</classLabel>
<newAxiom>'Microgram per Mole' SubClassOf 'Unit of Dose Calculation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176389</classIRI>
<classLabel>Short Supernumerary Rib</classLabel>
<newAxiom>'Short Supernumerary Rib' SubClassOf 'Supernumerary Rib'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176391</classIRI>
<classLabel>Qualitative Sexual Maturity Microscopic Examination</classLabel>
<newAxiom>'Qualitative Sexual Maturity Microscopic Examination' SubClassOf 'Microscopic Examination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176390</classIRI>
<classLabel>Peripubertal</classLabel>
<newAxiom>'Peripubertal' SubClassOf 'Developmental Stage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176395</classIRI>
<classLabel>Experimental Organism Malignant Pituicytoma</classLabel>
<newAxiom>'Experimental Organism Malignant Pituicytoma' SubClassOf 'Experimental Organism Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176394</classIRI>
<classLabel>Experimental Organism Amphophilic Vacuolar Adenoma</classLabel>
<newAxiom>'Experimental Organism Amphophilic Vacuolar Adenoma' SubClassOf 'Experimental Organism Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176393</classIRI>
<classLabel>Experimental Organism Amphophilic Vacuolar Carcinoma</classLabel>
<newAxiom>'Experimental Organism Amphophilic Vacuolar Carcinoma' SubClassOf 'Experimental Organism Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176392</classIRI>
<classLabel>Experimental Organism Benign Mesovarial Leiomyoma</classLabel>
<newAxiom>'Experimental Organism Benign Mesovarial Leiomyoma' SubClassOf 'Experimental Organism Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176498</classIRI>
<classLabel>AP-3 Complex Subunit Delta-1</classLabel>
<newAxiom>'AP-3 Complex Subunit Delta-1' EquivalentTo 'Transport Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Lysosome Assembly Pathway') and ('Gene_Product_Has_Chemical_Classification' some 'Scaffolding Protein') and ('Gene_Product_Has_Associated_Anatomy' some 'Golgi Apparatus') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Coiled-Coil Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Degranulation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Intracellular Transport') and ('Gene_Product_Encoded_By_Gene' some 'AP3D1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176497</classIRI>
<classLabel>AP3D1 wt Allele</classLabel>
<newAxiom>'AP3D1 wt Allele' SubClassOf 'AP3D1 Gene'</newAxiom>
<newAxiom>'AP3D1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '19p13.3'</newAxiom>
<newAxiom>'AP3D1 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Lysosome Assembly Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176496</classIRI>
<classLabel>AP3D1 Gene</classLabel>
<newAxiom>'AP3D1 Gene' SubClassOf 'Trafficking Protein Gene'</newAxiom>
<newAxiom>'AP3D1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Degranulation'</newAxiom>
<newAxiom>'AP3D1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Intracellular Transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176499</classIRI>
<classLabel>Approach</classLabel>
<newAxiom>'Approach' SubClassOf 'Action'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176487</classIRI>
<classLabel>Modified Health Care Climate Questionnaire for Breast Cancer Treatment</classLabel>
<newAxiom>'Modified Health Care Climate Questionnaire for Breast Cancer Treatment' SubClassOf 'Clinical or Research Assessment Questionnaire'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176486</classIRI>
<classLabel>AK2 wt Allele</classLabel>
<newAxiom>'AK2 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'Purine Metabolism Pathway'</newAxiom>
<newAxiom>'AK2 wt Allele' SubClassOf 'AK2 Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176485</classIRI>
<classLabel>Wavy</classLabel>
<newAxiom>'Wavy' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176484</classIRI>
<classLabel>Unexpanded</classLabel>
<newAxiom>'Unexpanded' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176489</classIRI>
<classLabel>Feel that Physician Understood How I Saw Things with Respect to Breast Cancer</classLabel>
<newAxiom>'Feel that Physician Understood How I Saw Things with Respect to Breast Cancer' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176488</classIRI>
<classLabel>Feel that Physician Provided Choices and Options for Breast Cancer Treatment</classLabel>
<newAxiom>'Feel that Physician Provided Choices and Options for Breast Cancer Treatment' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176490</classIRI>
<classLabel>Feel that Physician Expressed Confidence in my Ability to Make Decisions</classLabel>
<newAxiom>'Feel that Physician Expressed Confidence in my Ability to Make Decisions' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176494</classIRI>
<classLabel>Adenylate Kinase 2, Mitochondrial</classLabel>
<newAxiom>'Adenylate Kinase 2, Mitochondrial' EquivalentTo 'Phosphotransferase' and ('Gene_Product_Is_Element_In_Pathway' some 'Purine Metabolism Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Intermembrane Space of the Mitochondrion') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Phosphorylation Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Nucleotide Metabolic Process') and ('Gene_Product_Encoded_By_Gene' some 'AK2 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176493</classIRI>
<classLabel>Feel that Physician Tried to Understand How I Saw Things Before Offering Opinion</classLabel>
<newAxiom>'Feel that Physician Tried to Understand How I Saw Things Before Offering Opinion' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176492</classIRI>
<classLabel>Feel that Physician Encouraged Me to Ask Questions</classLabel>
<newAxiom>'Feel that Physician Encouraged Me to Ask Questions' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176491</classIRI>
<classLabel>Feel that Physician Listened to how I would Like to Handle Breast Cancer Treatment</classLabel>
<newAxiom>'Feel that Physician Listened to how I would Like to Handle Breast Cancer Treatment' SubClassOf 'Feelings Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176476</classIRI>
<classLabel>Hooked</classLabel>
<newAxiom>'Hooked' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176475</classIRI>
<classLabel>Eruption</classLabel>
<newAxiom>'Eruption' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176474</classIRI>
<classLabel>Domed</classLabel>
<newAxiom>'Domed' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176473</classIRI>
<classLabel>Curly</classLabel>
<newAxiom>'Curly' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176479</classIRI>
<classLabel>Vessel Biventricular Override</classLabel>
<newAxiom>'Vessel Biventricular Override' SubClassOf 'Cardiovascular System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176478</classIRI>
<classLabel>Kinked</classLabel>
<newAxiom>'Kinked' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176477</classIRI>
<classLabel>Imperforate</classLabel>
<newAxiom>'Imperforate' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176483</classIRI>
<classLabel>Two-Chambered</classLabel>
<newAxiom>'Two-Chambered' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176482</classIRI>
<classLabel>Transposed</classLabel>
<newAxiom>'Transposed' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176481</classIRI>
<classLabel>Three-Chambered</classLabel>
<newAxiom>'Three-Chambered' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176480</classIRI>
<classLabel>Patent</classLabel>
<newAxiom>'Patent' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176465</classIRI>
<classLabel>T-Cells Absent and Normal Natural Killer Cells and B-Cells</classLabel>
<newAxiom>'T-Cells Absent and Normal Natural Killer Cells and B-Cells' SubClassOf 'Abnormal Hematology Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176464</classIRI>
<classLabel>Recurrent Low Grade Astrocytoma</classLabel>
<newAxiom>'Recurrent Low Grade Astrocytoma' EquivalentTo 'Low Grade Astrocytoma' and 'Recurrent Glioma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176463</classIRI>
<classLabel>T-Cells, B-Cells and Natural Killer Cells Absent</classLabel>
<newAxiom>'T-Cells, B-Cells and Natural Killer Cells Absent' SubClassOf 'Abnormal Hematology Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176462</classIRI>
<classLabel>T-Cells Absent, T-Cell Receptor Signaling Defective and Natural Killer Cells and B-Cells Normal</classLabel>
<newAxiom>'T-Cells Absent, T-Cell Receptor Signaling Defective and Natural Killer Cells and B-Cells Normal' SubClassOf 'Abnormal Hematology Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176469</classIRI>
<classLabel>Ruler Measurement Method</classLabel>
<newAxiom>'Ruler Measurement Method' SubClassOf 'Examination Method'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176468</classIRI>
<classLabel>AK2 Gene</classLabel>
<newAxiom>'AK2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Nucleotide Metabolic Process'</newAxiom>
<newAxiom>'AK2 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Phosphorylation Process'</newAxiom>
<newAxiom>'AK2 Gene' SubClassOf 'Phosphotransferase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176467</classIRI>
<classLabel>Synovial Chondrosarcoma</classLabel>
<newAxiom>'Synovial Chondrosarcoma' EquivalentTo 'Chondrosarcoma' and 'Malignant Synovial Neoplasm' and 'Soft Tissue Sarcoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176466</classIRI>
<classLabel>T-Cells and B-Cells Absent and Natural Killer Cells Normal</classLabel>
<newAxiom>'T-Cells and B-Cells Absent and Natural Killer Cells Normal' SubClassOf 'Abnormal Hematology Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176472</classIRI>
<classLabel>Blunt-Tipped</classLabel>
<newAxiom>'Blunt-Tipped' SubClassOf 'General Qualifier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176471</classIRI>
<classLabel>pH Meter Measurement Method</classLabel>
<newAxiom>'pH Meter Measurement Method' SubClassOf 'Examination Method'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176470</classIRI>
<classLabel>Vernier Caliper Measurement Method</classLabel>
<newAxiom>'Vernier Caliper Measurement Method' SubClassOf 'Examination Method'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176454</classIRI>
<classLabel>OTULIN Gene</classLabel>
<newAxiom>'OTULIN Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Deubiquitination'</newAxiom>
<newAxiom>'OTULIN Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Negative Regulation of Inflammatory Response Process'</newAxiom>
<newAxiom>'OTULIN Gene' SubClassOf 'Cysteine Peptidase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176453</classIRI>
<classLabel>Mevalonate Kinase</classLabel>
<newAxiom>'Mevalonate Kinase' EquivalentTo 'Phosphotransferase' and ('Gene_Product_Is_Element_In_Pathway' some 'Terpenoid Biosynthesis Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Peroxisome Biogenesis Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Peroxisome') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Phosphorylation Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Biosynthetic Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cholesterol Homeostasis') and ('Gene_Product_Encoded_By_Gene' some 'MVK Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176452</classIRI>
<classLabel>MVK wt Allele</classLabel>
<newAxiom>'MVK wt Allele' EquivalentTo 'MVK Gene' and ('Gene_Is_Element_In_Pathway' some 'Terpenoid Biosynthesis Pathway') and ('Gene_Is_Element_In_Pathway' some 'Peroxisome Biogenesis Pathway') and ('Gene_In_Chromosomal_Location' some '12q24.11')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176451</classIRI>
<classLabel>MVK Gene</classLabel>
<newAxiom>'MVK Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cholesterol Homeostasis'</newAxiom>
<newAxiom>'MVK Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Phosphorylation Process'</newAxiom>
<newAxiom>'MVK Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Biosynthetic Process'</newAxiom>
<newAxiom>'MVK Gene' SubClassOf 'Kinase Family Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176458</classIRI>
<classLabel>PSTPIP1 Gene</classLabel>
<newAxiom>'PSTPIP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immune System Process'</newAxiom>
<newAxiom>'PSTPIP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cytoskeletal Modeling'</newAxiom>
<newAxiom>'PSTPIP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Protein Dephosphorylation'</newAxiom>
<newAxiom>'PSTPIP1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Inflammatory Response'</newAxiom>
<newAxiom>'PSTPIP1 Gene' SubClassOf 'Cytoskeletal Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176457</classIRI>
<classLabel>Gallium Ga 68 FAP-2286</classLabel>
<newAxiom>'Gallium Ga 68 FAP-2286' SubClassOf 'Radioimmunoconjugate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176456</classIRI>
<classLabel>Ubiquitin Thioesterase Otulin</classLabel>
<newAxiom>'Ubiquitin Thioesterase Otulin' EquivalentTo 'Cysteine Proteinase' and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoplasm') and ('Gene_Product_Has_Biochemical_Function' some 'Deubiquitinating Enzyme') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Deubiquitination') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Negative Regulation of Inflammatory Response Process') and ('Gene_Product_Encoded_By_Gene' some 'OTULIN Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176455</classIRI>
<classLabel>OTULIN wt Allele</classLabel>
<newAxiom>'OTULIN wt Allele' SubClassOf 'OTULIN Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176459</classIRI>
<classLabel>PSTPIP1 wt Allele</classLabel>
<newAxiom>'PSTPIP1 wt Allele' SubClassOf 'PSTPIP1 Gene'</newAxiom>
<newAxiom>'PSTPIP1 wt Allele' SubClassOf 'Gene_Is_Element_In_Pathway' some 'NOD-Like Receptor Signaling Pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176461</classIRI>
<classLabel>T-Cells and Natural Killer Cells Absent B-Cells Normal</classLabel>
<newAxiom>'T-Cells and Natural Killer Cells Absent B-Cells Normal' SubClassOf 'Abnormal Hematology Test Result'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176460</classIRI>
<classLabel>Proline-Serine-Threonine Phosphatase-Interacting Protein 1</classLabel>
<newAxiom>'Proline-Serine-Threonine Phosphatase-Interacting Protein 1' EquivalentTo 'Cytoskeletal Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'NOD-Like Receptor Signaling Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Leukocyte') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoskeleton') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'SH3 Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Coiled-Coil Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Actin-Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immune System Process') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Inflammatory Response') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cytoskeletal Modeling') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Protein Dephosphorylation') and ('Gene_Product_Encoded_By_Gene' some 'PSTPIP1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176443</classIRI>
<classLabel>LAT Gene Mutation</classLabel>
<newAxiom>'LAT Gene Mutation' SubClassOf 'Molecular_Abnormality_Involves_Gene' some 'LAT Gene'</newAxiom>
<newAxiom>'LAT Gene Mutation' SubClassOf 'Gene Variant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176442</classIRI>
<classLabel>How Often Thought about Chances of Cancer Recurrence</classLabel>
<newAxiom>'How Often Thought about Chances of Cancer Recurrence' SubClassOf 'Thinking Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176441</classIRI>
<classLabel>Cancer Worry Scale</classLabel>
<newAxiom>'Cancer Worry Scale' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176440</classIRI>
<classLabel>Linker for Activation of T-Cells Family Member 1</classLabel>
<newAxiom>'Linker for Activation of T-Cells Family Member 1' EquivalentTo 'Adaptor Signaling Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Natural Killer Cell-Mediated Cytotoxicity Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Fc Epsilon Receptor I Signaling Pathway KEGG') and ('Gene_Product_Is_Element_In_Pathway' some 'Fc Gamma Receptor-Mediated Phagocytosis Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells') and ('Gene_Product_Is_Element_In_Pathway' some 'T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells') and ('Gene_Product_Is_Element_In_Pathway' some 'Class I PI3K Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Fc-Epsilon Receptor I Signaling Pathway PID') and ('Gene_Product_Is_Element_In_Pathway' some 'JNK Signaling in the CD4+ TCR Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Mast Cell') and ('Gene_Product_Has_Associated_Anatomy' some 'Plasma Membrane') and ('Gene_Product_Has_Associated_Anatomy' some 'T-Lymphocyte and Natural Killer Cell') and ('Gene_Product_Expressed_In_Tissue' some 'Thymic Tissue') and ('Gene_Product_Expressed_In_Tissue' some 'Splenic Tissue') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Transmembrane Domain') and ('Gene_Product_Has_Biochemical_Function' some 'Transmembrane Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Immunity') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'T-Cell Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Inflammatory Response') and ('Gene_Product_Encoded_By_Gene' some 'LAT Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176447</classIRI>
<classLabel>How Often Worry about Developing Cancer</classLabel>
<newAxiom>'How Often Worry about Developing Cancer' SubClassOf 'Worry Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176446</classIRI>
<classLabel>How Concerned about Possibility of Cancer Recurrence</classLabel>
<newAxiom>'How Concerned about Possibility of Cancer Recurrence' SubClassOf 'Concern Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176445</classIRI>
<classLabel>Have Thoughts about Chances of Cancer Recurrence Interfered with Ability to Carry out Daily Activities</classLabel>
<newAxiom>'Have Thoughts about Chances of Cancer Recurrence Interfered with Ability to Carry out Daily Activities' SubClassOf 'Thinking Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176444</classIRI>
<classLabel>Have Thoughts of Chances of Cancer Recurrence Affected Mood</classLabel>
<newAxiom>'Have Thoughts of Chances of Cancer Recurrence Affected Mood' SubClassOf 'Thinking Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176449</classIRI>
<classLabel>How Often Worry about Chance of Family Members Developing Cancer</classLabel>
<newAxiom>'How Often Worry about Chance of Family Members Developing Cancer' SubClassOf 'Worry Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176448</classIRI>
<classLabel>How Much Problem is Worry About Developing Cancer</classLabel>
<newAxiom>'How Much Problem is Worry About Developing Cancer' SubClassOf 'How Big a Problem Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176450</classIRI>
<classLabel>How Concerned About Possibility of Needing Surgery Again</classLabel>
<newAxiom>'How Concerned About Possibility of Needing Surgery Again' SubClassOf 'Concern Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176432</classIRI>
<classLabel>RNF31 wt Allele</classLabel>
<newAxiom>'RNF31 wt Allele' EquivalentTo 'RNF31 Gene' and ('Gene_Is_Element_In_Pathway' some 'NOD-Like Receptor Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Shigellosis Pathway') and ('Gene_In_Chromosomal_Location' some '14q12')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176431</classIRI>
<classLabel>RNF31 Gene</classLabel>
<newAxiom>'RNF31 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Inflammatory Response'</newAxiom>
<newAxiom>'RNF31 Gene' SubClassOf 'Ubiquitin-Transferase Gene'</newAxiom>
<newAxiom>'RNF31 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Polyubiquitination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176430</classIRI>
<classLabel>RanBP-Type and C3HC4-Type Zinc Finger-Containing Protein 1</classLabel>
<newAxiom>'RanBP-Type and C3HC4-Type Zinc Finger-Containing Protein 1' EquivalentTo 'E3 Ubiquitin-Protein Transferase' and ('Gene_Product_Is_Element_In_Pathway' some 'NOD-Like Receptor Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Shigellosis Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytosol') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Ring Finger Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Coiled-Coil Domain') and ('Gene_Product_Is_Physical_Part_Of' some 'Linear Ubiquitin Chain Assembly Complex') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Polyubiquitination') and ('Gene_Product_Encoded_By_Gene' some 'RBCK1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176436</classIRI>
<classLabel>ITCH wt Allele</classLabel>
<newAxiom>'ITCH wt Allele' EquivalentTo 'ITCH Gene' and ('Gene_Is_Element_In_Pathway' some 'Ubiquitin-mediated Proteolysis Pathway') and ('Gene_Is_Element_In_Pathway' some 'Endocytosis Pathway') and ('Gene_Is_Element_In_Pathway' some 'Calcineurin-Dependent NFAT Signaling Pathway in Lymphocytes') and ('Gene_In_Chromosomal_Location' some '20q11.22')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176435</classIRI>
<classLabel>ITCH Gene</classLabel>
<newAxiom>'ITCH Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immunologic Factor Process'</newAxiom>
<newAxiom>'ITCH Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Ubiquitinated Protein Degradation'</newAxiom>
<newAxiom>'ITCH Gene' SubClassOf 'Ubiquitin-Transferase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176434</classIRI>
<classLabel>RNR Subunits Interaction Inhibitor TAS1553</classLabel>
<newAxiom>'RNR Subunits Interaction Inhibitor TAS1553' SubClassOf 'Chemical_Or_Drug_Affects_Gene_Product' some 'Ribonucleotide Reductase'</newAxiom>
<newAxiom>'RNR Subunits Interaction Inhibitor TAS1553' SubClassOf 'Ribonucleotide Reductase Inhibitor'</newAxiom>
<newAxiom>'RNR Subunits Interaction Inhibitor TAS1553' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Nucleotide Biosynthesis Process'</newAxiom>
<newAxiom>'RNR Subunits Interaction Inhibitor TAS1553' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'DNA Synthesis Inhibition'</newAxiom>
<newAxiom>'RNR Subunits Interaction Inhibitor TAS1553' SubClassOf 'Chemical_Or_Drug_Has_Physiologic_Effect' some 'Positive Regulation of Apoptosis'</newAxiom>
<newAxiom>'RNR Subunits Interaction Inhibitor TAS1553' SubClassOf 'Chemical_Or_Drug_Has_Mechanism_Of_Action' some 'Enzyme Inhibition'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176433</classIRI>
<classLabel>E3 Ubiquitin-Protein Ligase RNF31</classLabel>
<newAxiom>'E3 Ubiquitin-Protein Ligase RNF31' EquivalentTo 'E3 Ubiquitin-Protein Transferase' and ('Gene_Product_Is_Element_In_Pathway' some 'NOD-Like Receptor Signaling Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Shigellosis Pathway') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Ring Finger Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'UBA Domain') and ('Gene_Product_Is_Physical_Part_Of' some 'Linear Ubiquitin Chain Assembly Complex') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Inflammatory Response') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Polyubiquitination') and ('Gene_Product_Encoded_By_Gene' some 'RNF31 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176439</classIRI>
<classLabel>LAT wt Allele</classLabel>
<newAxiom>'LAT wt Allele' EquivalentTo 'LAT Gene' and ('Gene_Is_Element_In_Pathway' some 'Natural Killer Cell-Mediated Cytotoxicity Pathway') and ('Gene_Is_Element_In_Pathway' some 'T Cell Receptor Signaling Pathway KEGG') and ('Gene_Is_Element_In_Pathway' some 'Fc Epsilon Receptor I Signaling Pathway KEGG') and ('Gene_Is_Element_In_Pathway' some 'Fc Gamma Receptor-Mediated Phagocytosis Pathway') and ('Gene_Is_Element_In_Pathway' some 'T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells') and ('Gene_Is_Element_In_Pathway' some 'T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells') and ('Gene_Is_Element_In_Pathway' some 'Class I PI3K Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Fc-Epsilon Receptor I Signaling Pathway PID') and ('Gene_Is_Element_In_Pathway' some 'JNK Signaling in the CD4+ TCR Pathway') and ('Gene_Is_Element_In_Pathway' some 'PTPN1 Signaling Pathway') and ('Gene_In_Chromosomal_Location' some '16q13')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176438</classIRI>
<classLabel>LAT Gene</classLabel>
<newAxiom>'LAT Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Immunity'</newAxiom>
<newAxiom>'LAT Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'T-Cell Activation'</newAxiom>
<newAxiom>'LAT Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Inflammatory Response'</newAxiom>
<newAxiom>'LAT Gene' SubClassOf 'Adaptor Signaling Protein Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176437</classIRI>
<classLabel>E3 Ubiquitin-Protein Ligase Itchy Homolog</classLabel>
<newAxiom>'E3 Ubiquitin-Protein Ligase Itchy Homolog' EquivalentTo 'E3 Ubiquitin-Protein Transferase' and ('Gene_Product_Is_Element_In_Pathway' some 'Ubiquitin-mediated Proteolysis Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Endocytosis Pathway') and ('Gene_Product_Is_Element_In_Pathway' some 'Calcineurin-Dependent NFAT Signaling Pathway in Lymphocytes') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Proline-Rich Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'C2 Domain') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Ubiquitinated Protein Degradation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Negative Regulation of Immunologic Factor Signaling') and ('Gene_Product_Encoded_By_Gene' some 'ITCH Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176421</classIRI>
<classLabel>FOXN1 wt Allele</classLabel>
<newAxiom>'FOXN1 wt Allele' SubClassOf 'FOXN1 Gene'</newAxiom>
<newAxiom>'FOXN1 wt Allele' SubClassOf 'Gene_In_Chromosomal_Location' some '17q11.2'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176420</classIRI>
<classLabel>FOXN1 Gene</classLabel>
<newAxiom>'FOXN1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'T-Cell Differentiation'</newAxiom>
<newAxiom>'FOXN1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Keratinocyte Differentiation'</newAxiom>
<newAxiom>'FOXN1 Gene' SubClassOf 'Transcription Factor Gene'</newAxiom>
<newAxiom>'FOXN1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'DNA Binding'</newAxiom>
<newAxiom>'FOXN1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Transcriptional Activation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176425</classIRI>
<classLabel>Single Item Literacy Screener</classLabel>
<newAxiom>'Single Item Literacy Screener' SubClassOf 'Research or Clinical Assessment Tool'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424</classIRI>
<classLabel>NCI Drug Dictionary Terminology</classLabel>
<newAxiom>'NCI Drug Dictionary Terminology' SubClassOf 'National Cancer Institute Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176423</classIRI>
<classLabel>Forkhead Box Protein N1</classLabel>
<newAxiom>'Forkhead Box Protein N1' EquivalentTo 'Transcription Factor' and ('Gene_Product_Has_Associated_Anatomy' some 'Nucleus') and ('Gene_Product_Expressed_In_Tissue' some 'Epidermis') and ('Gene_Product_Expressed_In_Tissue' some 'Thymic Epithelial Tissue') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Forkhead Box') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Transcriptional Activation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'DNA Binding') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'T-Cell Differentiation') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Keratinocyte Differentiation') and ('Gene_Product_Encoded_By_Gene' some 'FOXN1 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176422</classIRI>
<classLabel>Charlson Comorbidity Index</classLabel>
<newAxiom>'Charlson Comorbidity Index' SubClassOf 'Clinical or Research Assessment Questionnaire'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176429</classIRI>
<classLabel>RBCK1 wt Allele</classLabel>
<newAxiom>'RBCK1 wt Allele' EquivalentTo 'RBCK1 Gene' and ('Gene_Is_Element_In_Pathway' some 'NOD-Like Receptor Signaling Pathway') and ('Gene_Is_Element_In_Pathway' some 'Shigellosis Pathway') and ('Gene_In_Chromosomal_Location' some '20p13')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176428</classIRI>
<classLabel>How Often Need Help Reading Instructions, Pamphlets, or other Written Material from Doctor or Pharmacy</classLabel>
<newAxiom>'How Often Need Help Reading Instructions, Pamphlets, or other Written Material from Doctor or Pharmacy' SubClassOf 'Reading Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176427</classIRI>
<classLabel>RBCK1 Gene</classLabel>
<newAxiom>'RBCK1 Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Polyubiquitination'</newAxiom>
<newAxiom>'RBCK1 Gene' SubClassOf 'Ubiquitin-Transferase Gene'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176426</classIRI>
<classLabel>Reading Question</classLabel>
<newAxiom>'Reading Question' SubClassOf 'Clinical or Research Assessment Question'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176410</classIRI>
<classLabel>Tertiary Lymphoid Structure</classLabel>
<newAxiom>'Tertiary Lymphoid Structure' SubClassOf 'Immune System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176414</classIRI>
<classLabel>Breast Schwannoma</classLabel>
<newAxiom>'Breast Schwannoma' EquivalentTo 'Peripheral Nerve Schwannoma' and 'Benign Breast Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176413</classIRI>
<classLabel>Test Site Activity</classLabel>
<newAxiom>'Test Site Activity' SubClassOf 'Study Activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176412</classIRI>
<classLabel>Reproductive Tissue</classLabel>
<newAxiom>'Reproductive Tissue' SubClassOf 'Tissue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176411</classIRI>
<classLabel>Increased Hassall's Corpuscles</classLabel>
<newAxiom>'Increased Hassall's Corpuscles' SubClassOf 'Morphologic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176418</classIRI>
<classLabel>CORO1A wt Allele</classLabel>
<newAxiom>'CORO1A wt Allele' EquivalentTo 'CORO1A Gene' and ('Gene_Is_Element_In_Pathway' some 'Phagocytosis Pathway') and ('Gene_In_Chromosomal_Location' some '16p11.2')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176417</classIRI>
<classLabel>CORO1A Gene</classLabel>
<newAxiom>'CORO1A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Chemotaxis Induction'</newAxiom>
<newAxiom>'CORO1A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cytoskeletal Modeling'</newAxiom>
<newAxiom>'CORO1A Gene' SubClassOf 'Cytoskeletal Gene'</newAxiom>
<newAxiom>'CORO1A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Phagocytosis'</newAxiom>
<newAxiom>'CORO1A Gene' SubClassOf 'Gene_Plays_Role_In_Process' some 'Cellular Migration Process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176416</classIRI>
<classLabel>Immunodeficiency with Hyper-IgM, Type 3</classLabel>
<newAxiom>'Immunodeficiency with Hyper-IgM, Type 3' EquivalentTo 'Immunodeficiency with Hyper-IgM' and ('Disease_Mapped_To_Gene' some 'CD40 Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176415</classIRI>
<classLabel>Breast Neurofibroma</classLabel>
<newAxiom>'Breast Neurofibroma' EquivalentTo 'Neurofibroma' and 'Benign Breast Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176419</classIRI>
<classLabel>Coronin-1A</classLabel>
<newAxiom>'Coronin-1A' EquivalentTo 'Cytoskeletal Protein' and ('Gene_Product_Is_Element_In_Pathway' some 'Phagocytosis Pathway') and ('Gene_Product_Has_Associated_Anatomy' some 'Cytoskeleton') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'Coiled-Coil Domain') and ('Gene_Product_Has_Structural_Domain_Or_Motif' some 'WD Repeat') and ('Gene_Product_Has_Biochemical_Function' some 'Actin-Binding Protein') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cytoskeletal Modeling') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Phagocytosis') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Cell Movement') and ('Gene_Product_Plays_Role_In_Biological_Process' some 'Chemotaxis Induction') and ('Gene_Product_Encoded_By_Gene' some 'CORO1A Gene')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176403</classIRI>
<classLabel>Increased Thymic Epithelium-Free Areas</classLabel>
<newAxiom>'Increased Thymic Epithelium-Free Areas' SubClassOf 'Morphologic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176402</classIRI>
<classLabel>Increased Corticomedullary Ratio</classLabel>
<newAxiom>'Increased Corticomedullary Ratio' SubClassOf 'Morphologic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176401</classIRI>
<classLabel>Decreased Corticomedullary Ratio</classLabel>
<newAxiom>'Decreased Corticomedullary Ratio' SubClassOf 'Morphologic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176400</classIRI>
<classLabel>Splenic Contraction</classLabel>
<newAxiom>'Splenic Contraction' SubClassOf 'Hematopoietic System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176407</classIRI>
<classLabel>Experimental Organism Increased Serosa-Associated Lymphoid Clusters</classLabel>
<newAxiom>'Experimental Organism Increased Serosa-Associated Lymphoid Clusters' SubClassOf 'Experimental Organism Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176406</classIRI>
<classLabel>Increased Number of Hypersegmented Neutrophils Present</classLabel>
<newAxiom>'Increased Number of Hypersegmented Neutrophils Present' SubClassOf 'Hypersegmented Neutrophils Present'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176405</classIRI>
<classLabel>Hyaline Material</classLabel>
<newAxiom>'Hyaline Material' SubClassOf 'Morphologic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176404</classIRI>
<classLabel>Loss of Corticomedullary Distinction</classLabel>
<newAxiom>'Loss of Corticomedullary Distinction' SubClassOf 'Morphologic Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176409</classIRI>
<classLabel>Gelatinous Bone Marrow Transformation</classLabel>
<newAxiom>'Gelatinous Bone Marrow Transformation' SubClassOf 'Bone Marrow Disorder'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176408</classIRI>
<classLabel>Age-Related Thymic Involution</classLabel>
<newAxiom>'Age-Related Thymic Involution' SubClassOf 'Immune System Finding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176256</classIRI>
<classLabel>Activity Time Answer</classLabel>
<newAxiom>'Activity Time Answer' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176255</classIRI>
<classLabel>Breast Angiolipoma</classLabel>
<newAxiom>'Breast Angiolipoma' EquivalentTo 'Angiolipoma' and 'Breast Lipoma'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176254</classIRI>
<classLabel>Walking Answer</classLabel>
<newAxiom>'Walking Answer' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176253</classIRI>
<classLabel>Breast Nodular Fasciitis</classLabel>
<newAxiom>'Breast Nodular Fasciitis' EquivalentTo 'Nodular Fasciitis' and 'Breast Soft Tissue Neoplasm' and 'Benign Breast Neoplasm'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176259</classIRI>
<classLabel>Health Literacy</classLabel>
<newAxiom>'Health Literacy' SubClassOf 'Literacy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176258</classIRI>
<classLabel>Deep Learning</classLabel>
<newAxiom>'Deep Learning' SubClassOf 'Machine Learning'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176257</classIRI>
<classLabel>Decentralized Clinical Trial</classLabel>
<newAxiom>'Decentralized Clinical Trial' SubClassOf 'Clinical Trial'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176263</classIRI>
<classLabel>Synthetic Data</classLabel>
<newAxiom>'Synthetic Data' SubClassOf 'Data'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176262</classIRI>
<classLabel>Plain Language Writing</classLabel>
<newAxiom>'Plain Language Writing' SubClassOf 'Style'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176261</classIRI>
<classLabel>Study Phase</classLabel>
<newAxiom>'Study Phase' SubClassOf 'Phase'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176260</classIRI>
<classLabel>Natural Language Processing</classLabel>
<newAxiom>'Natural Language Processing' SubClassOf 'Computer Sciences'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176245</classIRI>
<classLabel>Never Answer</classLabel>
<newAxiom>'Never Answer' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176244</classIRI>
<classLabel>Agreement Answer</classLabel>
<newAxiom>'Agreement Answer' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176243</classIRI>
<classLabel>Difficulty Answer</classLabel>
<newAxiom>'Difficulty Answer' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176242</classIRI>
<classLabel>Time Amount Answer</classLabel>
<newAxiom>'Time Amount Answer' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176249</classIRI>
<classLabel>Hearing Answer</classLabel>
<newAxiom>'Hearing Answer' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176248</classIRI>
<classLabel>Cough Answer</classLabel>
<newAxiom>'Cough Answer' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176247</classIRI>
<classLabel>Extremity Pain Answer</classLabel>
<newAxiom>'Extremity Pain Answer' SubClassOf 'Pain Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176246</classIRI>
<classLabel>Pain Answer</classLabel>
<newAxiom>'Pain Answer' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176252</classIRI>
<classLabel>Sexual Activity Answer</classLabel>
<newAxiom>'Sexual Activity Answer' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176251</classIRI>
<classLabel>Primary Breast Angiosarcoma</classLabel>
<newAxiom>'Primary Breast Angiosarcoma' EquivalentTo 'Breast Angiosarcoma' and ('Disease_Excludes_Finding' some 'Radiation Toxicity')</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176250</classIRI>
<classLabel>Satisfaction Answer</classLabel>
<newAxiom>'Satisfaction Answer' SubClassOf 'Clinical or Research Assessment Answer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176234</classIRI>
<classLabel>Lower Gastrointestinal Tract Lymph Node</classLabel>
<newAxiom>'Lower Gastrointestinal Tract Lymph Node' SubClassOf 'Lymph Node by Anatomic Site'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176233</classIRI>
<classLabel>Gastrointestinal Tract Wall</classLabel>
<newAxiom>'Gastrointestinal Tract Wall' SubClassOf 'Digestive System Part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176232</classIRI>
<classLabel>Cholate Compounds Measurement</classLabel>
<newAxiom>'Cholate Compounds Measurement' SubClassOf 'Bile Acid Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176231</classIRI>
<classLabel>Machine Learning</classLabel>
<newAxiom>'Machine Learning' SubClassOf 'Computer Sciences'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176238</classIRI>
<classLabel>Ursodeoxycholate Compounds Measurement</classLabel>
<newAxiom>'Ursodeoxycholate Compounds Measurement' SubClassOf 'Cholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176237</classIRI>
<classLabel>Ratio AUC to Last Nonzero Concentration</classLabel>
<newAxiom>'Ratio AUC to Last Nonzero Concentration' SubClassOf 'Area Under the Curve Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176236</classIRI>
<classLabel>Ratio AUC From T1 to T2</classLabel>
<newAxiom>'Ratio AUC From T1 to T2' SubClassOf 'Area Under the Curve Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176235</classIRI>
<classLabel>Concentration Ratio</classLabel>
<newAxiom>'Concentration Ratio' SubClassOf 'Ratio'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176239</classIRI>
<classLabel>Chenodeoxycholate Compounds Measurement</classLabel>
<newAxiom>'Chenodeoxycholate Compounds Measurement' SubClassOf 'Cholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176241</classIRI>
<classLabel>Lower Gastrointestinal Tract Wall</classLabel>
<newAxiom>'Lower Gastrointestinal Tract Wall' SubClassOf 'Gastrointestinal Tract Wall'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176240</classIRI>
<classLabel>Lithocholate Compounds Measurement</classLabel>
<newAxiom>'Lithocholate Compounds Measurement' SubClassOf 'Cholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176223</classIRI>
<classLabel>Devil Facial Tumor Disease 1</classLabel>
<newAxiom>'Devil Facial Tumor Disease 1' SubClassOf 'Devil Facial Tumor Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176222</classIRI>
<classLabel>Autologous Anti-GPRC5D-CAR-4-1BB-expressing T-cells MCARH109</classLabel>
<newAxiom>'Autologous Anti-GPRC5D-CAR-4-1BB-expressing T-cells MCARH109' SubClassOf 'Chimeric Antigen Receptor T-cells'</newAxiom>
<newAxiom>'Autologous Anti-GPRC5D-CAR-4-1BB-expressing T-cells MCARH109' SubClassOf 'Antineoplastic Immune Cell'</newAxiom>
<newAxiom>'Autologous Anti-GPRC5D-CAR-4-1BB-expressing T-cells MCARH109' SubClassOf 'Therapeutic Autologous Lymphocytes'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176221</classIRI>
<classLabel>Linear Ubiquitin Chain Assembly Complex</classLabel>
<newAxiom>'Linear Ubiquitin Chain Assembly Complex' SubClassOf 'Ubiquitin Protein Ligase'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176227</classIRI>
<classLabel>CDISC Define-XML ADaM Occurrence Data Structure Subclass Terminology</classLabel>
<newAxiom>'CDISC Define-XML ADaM Occurrence Data Structure Subclass Terminology' SubClassOf 'CDISC Define-XML Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176226</classIRI>
<classLabel>CDISC SEND Microscopy Sexual Maturity Status Terminology</classLabel>
<newAxiom>'CDISC SEND Microscopy Sexual Maturity Status Terminology' SubClassOf 'CDISC SEND Terminology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176225</classIRI>
<classLabel>Hemopurification</classLabel>
<newAxiom>'Hemopurification' SubClassOf 'Blood Treatment'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176224</classIRI>
<classLabel>Devil Facial Tumor Disease 2</classLabel>
<newAxiom>'Devil Facial Tumor Disease 2' SubClassOf 'Devil Facial Tumor Disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176229</classIRI>
<classLabel>District</classLabel>
<newAxiom>'District' SubClassOf 'Geographic Area'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176228</classIRI>
<classLabel>Subject Decision</classLabel>
<newAxiom>'Subject Decision' SubClassOf 'Decision'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176230</classIRI>
<classLabel>Contact Name</classLabel>
<newAxiom>'Contact Name' SubClassOf 'Name'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176299</classIRI>
<classLabel>Glycocholate Measurement</classLabel>
<newAxiom>'Glycocholate Measurement' SubClassOf 'Cholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176298</classIRI>
<classLabel>Ursodeoxycholate Measurement</classLabel>
<newAxiom>'Ursodeoxycholate Measurement' SubClassOf 'Ursodeoxycholate Compounds Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176297</classIRI>
<classLabel>Aspartate Aminotransferase to Alanine Aminotransferase Ratio Measurement</classLabel>
<newAxiom>'Aspartate Aminotransferase to Alanine Aminotransferase Ratio Measurement' SubClassOf 'Protein or Enzyme Type Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176289</classIRI>
<classLabel>Three Times Per Cycle</classLabel>
<newAxiom>'Three Times Per Cycle' SubClassOf 'Schedule Frequency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176288</classIRI>
<classLabel>Two Times Per Cycle</classLabel>
<newAxiom>'Two Times Per Cycle' SubClassOf 'Schedule Frequency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176287</classIRI>
<classLabel>Information Source for Cause of Death</classLabel>
<newAxiom>'Information Source for Cause of Death' SubClassOf 'Source'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176286</classIRI>
<classLabel>Section Thickness</classLabel>
<newAxiom>'Section Thickness' SubClassOf 'Thickness'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176292</classIRI>
<classLabel>Primary Care Physician's Office Visit</classLabel>
<newAxiom>'Primary Care Physician's Office Visit' SubClassOf 'Patient Visit'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176291</classIRI>
<classLabel>Percent Ulcer Area</classLabel>
<newAxiom>'Percent Ulcer Area' SubClassOf 'Percent Unit'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176290</classIRI>
<classLabel>Every Two Days</classLabel>
<newAxiom>'Every Two Days' SubClassOf 'Retired Concept Current Year'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176296</classIRI>
<classLabel>Whole Blood Equivalent Glucose Measurement</classLabel>
<newAxiom>'Whole Blood Equivalent Glucose Measurement' SubClassOf 'Blood Glucose Measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176295</classIRI>
<classLabel>Modification of Diet in Renal Disease Formula</classLabel>
<newAxiom>'Modification of Diet in Renal Disease Formula' SubClassOf 'Statistical Technique'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176294</classIRI>
<classLabel>Emergency Room Visit</classLabel>
<newAxiom>'Emergency Room Visit' SubClassOf 'Patient Visit'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176293</classIRI>
<classLabel>Specialty Care Physician's Office Visit</classLabel>
<newAxiom>'Specialty Care Physician's Office Visit' SubClassOf 'Patient Visit'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176278</classIRI>
<classLabel>Maximum Dose Amount</classLabel>
<newAxiom>'Maximum Dose Amount' SubClassOf 'Dose'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176277</classIRI>
<classLabel>Number of Devices Present</classLabel>
<newAxiom>'Number of Devices Present' SubClassOf 'Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176276</classIRI>
<classLabel>Number of Tissue Samples in Specimen</classLabel>
<newAxiom>'Number of Tissue Samples in Specimen' SubClassOf 'Number'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176275</classIRI>
<classLabel>Study Product Manufacturer</classLabel>
<newAxiom>'Study Product Manufacturer' SubClassOf 'Manufacturer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176279</classIRI>
<classLabel>Frequency of Maximum Dose Amount</classLabel>
<newAxiom>'Frequency of Maximum Dose Amount' SubClassOf 'Dose Frequency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176281</classIRI>
<classLabel>Frequency of Final Dose Amount</classLabel>
<newAxiom>'Frequency of Final Dose Amount' SubClassOf 'Dose Frequency'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176280</classIRI>
<classLabel>Final Dose Amount</classLabel>
<newAxiom>'Final Dose Amount' SubClassOf 'Dose'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176285</classIRI>
<classLabel>Substance Dependence Indicator</classLabel>
<newAxiom>'Substance Dependence Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176284</classIRI>
<classLabel>Unable to Discontinue Use Due to Dependence Indicator</classLabel>
<newAxiom>'Unable to Discontinue Use Due to Dependence Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176283</classIRI>
<classLabel>Relapse after Discontinuation Because of Dependence Indicator</classLabel>
<newAxiom>'Relapse after Discontinuation Because of Dependence Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176282</classIRI>
<classLabel>Unable to Taper Dependent Indicator</classLabel>
<newAxiom>'Unable to Taper Dependent Indicator' SubClassOf 'Indicator'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176267</classIRI>
<classLabel>Study Product Accountability</classLabel>
<newAxiom>'Study Product Accountability' SubClassOf 'Study Activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176266</classIRI>
<classLabel>Study Product Acquisition</classLabel>
<newAxiom>'Study Product Acquisition' SubClassOf 'Acquisition'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176265</classIRI>
<classLabel>Adverse Event Dataset</classLabel>
<newAxiom>'Adverse Event Dataset' SubClassOf 'Data Set'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176264</classIRI>
<classLabel>Virtual</classLabel>
<newAxiom>'Virtual' SubClassOf 'Conceptual Entity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176269</classIRI>
<classLabel>Study Product Appearance</classLabel>
<newAxiom>'Study Product Appearance' SubClassOf 'Appearance'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176268</classIRI>
<classLabel>Study Product Formulation</classLabel>
<newAxiom>'Study Product Formulation' SubClassOf 'Pharmaceutical Formulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176270</classIRI>
<classLabel>Study Product Packaging</classLabel>
<newAxiom>'Study Product Packaging' SubClassOf 'Drug Package'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176274</classIRI>
<classLabel>Study Product Preparation</classLabel>
<newAxiom>'Study Product Preparation' SubClassOf 'Preparation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176273</classIRI>
<classLabel>Study Product Stability</classLabel>
<newAxiom>'Study Product Stability' SubClassOf 'Medical Product Stability'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176272</classIRI>
<classLabel>Study Product Storage</classLabel>
<newAxiom>'Study Product Storage' SubClassOf 'Storage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176271</classIRI>
<classLabel>Study Product Labeling</classLabel>
<newAxiom>'Study Product Labeling' SubClassOf 'Labeling'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>