<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
161
</numberChangedClasses>
<numberNewClasses>
47
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_25435</classIRI>
<classLabel>mutagen</classLabel>
<newAxiom>&apos;mutagen&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_38637</classIRI>
<classLabel>tyrosine kinase inhibitor</classLabel>
<newAxiom>&apos;tyrosine kinase inhibitor&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0001824</classIRI>
<classLabel>hormone role</classLabel>
<newAxiom>&apos;hormone role&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_33229</classIRI>
<classLabel>vitamin</classLabel>
<newAxiom>&apos;vitamin&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_16449</classIRI>
<classLabel>alanine</classLabel>
<deletedAxiom>&apos;alanine&apos; SubClassOf &apos;creatinine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0003912</classIRI>
<classLabel>ankle brachial index</classLabel>
<deletedAxiom>&apos;ankle brachial index&apos; SubClassOf &apos;cardiovascular measurement&apos;</deletedAxiom>
<newAxiom>&apos;ankle brachial index&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0003926</classIRI>
<classLabel>neuropsychological test</classLabel>
<deletedAxiom>&apos;neuropsychological test&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;neuropsychological test&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005941</classIRI>
<classLabel>mammographic density measurement</classLabel>
<deletedAxiom>&apos;mammographic density measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;mammographic density measurement&apos; SubClassOf &apos;cancer biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005949</classIRI>
<classLabel>antinuclear antibody measurement</classLabel>
<newAxiom>&apos;antinuclear antibody measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006846</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_24432</classIRI>
<classLabel>biological role</classLabel>
<deletedAxiom>&apos;biological role&apos; SubClassOf &apos;chemical role&apos;</deletedAxiom>
<newAxiom>&apos;biological role&apos; SubClassOf &apos;role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0003787</classIRI>
<classLabel>cytokine role</classLabel>
<newAxiom>&apos;cytokine role&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0003779</classIRI>
<classLabel>autoimmune thyroid disease</classLabel>
<deletedAxiom>&apos;autoimmune thyroid disease&apos; SubClassOf &apos;autoimmune disease&apos;</deletedAxiom>
<newAxiom>&apos;autoimmune thyroid disease&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006812</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004830</classIRI>
<classLabel>caudate nucleus volume</classLabel>
<deletedAxiom>&apos;caudate nucleus volume&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;caudate nucleus volume&apos; SubClassOf &apos;Alzheimer&apos;s disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004839</classIRI>
<classLabel>CD4:CD8 lymphocyte ratio</classLabel>
<deletedAxiom>&apos;CD4:CD8 lymphocyte ratio&apos; SubClassOf &apos;hematological measurement&apos;</deletedAxiom>
<newAxiom>&apos;CD4:CD8 lymphocyte ratio&apos; SubClassOf &apos;inflammatory marker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004819</classIRI>
<classLabel>resistin measurement</classLabel>
<newAxiom>&apos;resistin measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006846</newAxiom>
<newAxiom>&apos;resistin measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006842</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004806</classIRI>
<classLabel>asbestos exposure measurement</classLabel>
<deletedAxiom>&apos;asbestos exposure measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;asbestos exposure measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006841</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004808</classIRI>
<classLabel>L lactate dehydrogenase measurement</classLabel>
<deletedAxiom>&apos;L lactate dehydrogenase measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;L lactate dehydrogenase measurement&apos; SubClassOf &apos;hematological measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_16737</classIRI>
<classLabel>creatinine</classLabel>
<deletedAxiom>&apos;creatinine&apos; EquivalentTo &apos;metabolite&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_27026</classIRI>
<classLabel>toxin</classLabel>
<newAxiom>&apos;toxin&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_27027</classIRI>
<classLabel>micronutrient</classLabel>
<newAxiom>&apos;micronutrient&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_16811</classIRI>
<classLabel>methionine</classLabel>
<deletedAxiom>&apos;methionine&apos; SubClassOf &apos;creatinine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004749</classIRI>
<classLabel>CCL2 measurement</classLabel>
<deletedAxiom>&apos;CCL2 measurement&apos; SubClassOf &apos;inflammatory marker measurement&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004746</classIRI>
<classLabel>lipoprotein-associated phospholipase A(2) measurement</classLabel>
<deletedAxiom>&apos;lipoprotein-associated phospholipase A(2) measurement&apos; SubClassOf &apos;cardiovascular measurement&apos;</deletedAxiom>
<newAxiom>&apos;lipoprotein-associated phospholipase A(2) measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004751</classIRI>
<classLabel>CCL4 measurement</classLabel>
<deletedAxiom>&apos;CCL4 measurement&apos; SubClassOf &apos;inflammatory marker measurement&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004728</classIRI>
<classLabel>serum amyloid A protein measurement</classLabel>
<newAxiom>&apos;serum amyloid A protein measurement&apos; SubClassOf &apos;cancer biomarker measurement&apos;</newAxiom>
<newAxiom>&apos;serum amyloid A protein measurement&apos; SubClassOf &apos;alpha globulin measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004727</classIRI>
<classLabel>metabolite</classLabel>
<deletedAxiom>&apos;metabolite&apos; SubClassOf &apos;organic heterocyclic compound&apos;</deletedAxiom>
<deletedAxiom>&apos;creatinine&apos; EquivalentTo &apos;metabolite&apos;</deletedAxiom>
<newAxiom>&apos;metabolite&apos; SubClassOf &apos;chemical compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004724</classIRI>
<classLabel>carotid-femoral pulse wave velocity</classLabel>
<deletedAxiom>&apos;carotid-femoral pulse wave velocity&apos; SubClassOf &apos;cardiovascular measurement&apos;</deletedAxiom>
<newAxiom>&apos;carotid-femoral pulse wave velocity&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004739</classIRI>
<classLabel>circulating cell free DNA measurement</classLabel>
<deletedAxiom>&apos;circulating cell free DNA measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;circulating cell free DNA measurement&apos; SubClassOf &apos;cancer biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004733</classIRI>
<classLabel>anti-cyclic citrullinated peptide antibody measurement</classLabel>
<newAxiom>&apos;anti-cyclic citrullinated peptide antibody measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006846</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004735</classIRI>
<classLabel>serum alanine aminotransferase measurement</classLabel>
<newAxiom>&apos;serum alanine aminotransferase measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006845</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004736</classIRI>
<classLabel>aspartate aminotransferase measurement</classLabel>
<newAxiom>&apos;aspartate aminotransferase measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006845</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004786</classIRI>
<classLabel>Mini-International Neuropsychiatric Interview</classLabel>
<deletedAxiom>&apos;Mini-International Neuropsychiatric Interview&apos; SubClassOf &apos;behavior or behavioral disorder measurement&apos;</deletedAxiom>
<newAxiom>&apos;Mini-International Neuropsychiatric Interview&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004785</classIRI>
<classLabel>South Texas Assessment of Neurocognition</classLabel>
<deletedAxiom>&apos;South Texas Assessment of Neurocognition&apos; SubClassOf &apos;behavior or behavioral disorder measurement&apos;</deletedAxiom>
<newAxiom>&apos;South Texas Assessment of Neurocognition&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004789</classIRI>
<classLabel>atrial natriuretic factor measurement</classLabel>
<deletedAxiom>&apos;atrial natriuretic factor measurement&apos; SubClassOf &apos;cardiovascular measurement&apos;</deletedAxiom>
<newAxiom>&apos;atrial natriuretic factor measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004783</classIRI>
<classLabel>TEMPS-A questionnaire</classLabel>
<deletedAxiom>&apos;TEMPS-A questionnaire&apos; SubClassOf &apos;behavior or behavioral disorder measurement&apos;</deletedAxiom>
<newAxiom>&apos;TEMPS-A questionnaire&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004781</classIRI>
<classLabel>DSM-IV-based  non-social scale</classLabel>
<deletedAxiom>&apos;DSM-IV-based  non-social scale&apos; SubClassOf &apos;behavior or behavioral disorder measurement&apos;</deletedAxiom>
<newAxiom>&apos;DSM-IV-based  non-social scale&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004780</classIRI>
<classLabel>DSM-IV-based social scale</classLabel>
<deletedAxiom>&apos;DSM-IV-based social scale&apos; SubClassOf &apos;behavior or behavioral disorder measurement&apos;</deletedAxiom>
<newAxiom>&apos;DSM-IV-based social scale&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004763</classIRI>
<classLabel>p-tau measurement</classLabel>
<deletedAxiom>&apos;p-tau measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;p-tau measurement&apos; SubClassOf &apos;Alzheimer&apos;s disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004761</classIRI>
<classLabel>uric acid measurement</classLabel>
<deletedAxiom>&apos;uric acid measurement&apos; SubClassOf &apos;renal system measurement&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004779</classIRI>
<classLabel>CHAOS measure</classLabel>
<deletedAxiom>&apos;CHAOS measure&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;CHAOS measure&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004713</classIRI>
<classLabel>FEV/FEC ratio</classLabel>
<newAxiom>&apos;FEV/FEC ratio&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006841</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_16919</classIRI>
<classLabel>creatine</classLabel>
<deletedAxiom>&apos;creatine&apos; SubClassOf &apos;creatinine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004614</classIRI>
<classLabel>apolipoprotein A 1 measurement</classLabel>
<newAxiom>&apos;apolipoprotein A 1 measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004611</classIRI>
<classLabel>low density lipoprotein cholesterol measurement</classLabel>
<newAxiom>&apos;low density lipoprotein cholesterol measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004624</classIRI>
<classLabel>prostate specific antigen measurement</classLabel>
<deletedAxiom>&apos;prostate specific antigen measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;prostate specific antigen measurement&apos; SubClassOf &apos;cancer biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004633</classIRI>
<classLabel>protein C measurement</classLabel>
<newAxiom>&apos;protein C measurement&apos; SubClassOf &apos;alpha globulin measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004635</classIRI>
<classLabel>leptin receptor measurement</classLabel>
<deletedAxiom>&apos;leptin receptor measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;leptin receptor measurement&apos; SubClassOf &apos;hormone measurement&apos;</newAxiom>
<newAxiom>&apos;leptin receptor measurement&apos; SubClassOf &apos;protein measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004640</classIRI>
<classLabel>haptoglobin measurement</classLabel>
<newAxiom>&apos;haptoglobin measurement&apos; SubClassOf &apos;alpha globulin measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004644</classIRI>
<classLabel>TPE interval measurement</classLabel>
<deletedAxiom>&apos;TPE interval measurement&apos; SubClassOf &apos;cardiovascular measurement&apos;</deletedAxiom>
<newAxiom>&apos;TPE interval measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004642</classIRI>
<classLabel>cortisol secretion measurement</classLabel>
<newAxiom>&apos;cortisol secretion measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_24127</classIRI>
<classLabel>fungicide</classLabel>
<newAxiom>&apos;fungicide&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004670</classIRI>
<classLabel>beta-amyloid 1-42 measurement</classLabel>
<newAxiom>&apos;beta-amyloid 1-42 measurement&apos; SubClassOf &apos;Alzheimer&apos;s disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_26155</classIRI>
<classLabel>plant growth regulator</classLabel>
<newAxiom>&apos;plant growth regulator&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004980</classIRI>
<classLabel>appendicular lean mass</classLabel>
<newAxiom>&apos;appendicular lean mass&apos; SubClassOf &apos;bone fracture related measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004984</classIRI>
<classLabel>complement C4 measurement</classLabel>
<deletedAxiom>&apos;complement C4 measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;complement C4 measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006846</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004985</classIRI>
<classLabel>platelet reactivity measurement</classLabel>
<newAxiom>&apos;platelet reactivity measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004983</classIRI>
<classLabel>complement C3 measurement</classLabel>
<deletedAxiom>&apos;complement C3 measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;complement C3 measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006846</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004993</classIRI>
<classLabel>serum IgM measurement</classLabel>
<deletedAxiom>&apos;serum IgM measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;serum IgM measurement&apos; SubClassOf &apos;cancer biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004913</classIRI>
<classLabel>lentiform nucleus measurement</classLabel>
<deletedAxiom>&apos;lentiform nucleus measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;lentiform nucleus measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004910</classIRI>
<classLabel>CYP3A4 activity</classLabel>
<deletedAxiom>&apos;CYP3A4 activity&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;CYP3A4 activity&apos; SubClassOf &apos;liver enzyme measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004846</classIRI>
<classLabel>serotonin measurement</classLabel>
<deletedAxiom>&apos;serotonin measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;serotonin measurement&apos; SubClassOf &apos;cancer biomarker measurement&apos;</newAxiom>
<newAxiom>&apos;serotonin measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004840</classIRI>
<classLabel>cortical thickness</classLabel>
<newAxiom>&apos;cortical thickness&apos; SubClassOf &apos;Alzheimer&apos;s disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004866</classIRI>
<classLabel>autoantibody measurement</classLabel>
<newAxiom>&apos;autoantibody measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006846</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004860</classIRI>
<classLabel>common carotid intimal medial thickness</classLabel>
<deletedAxiom>&apos;common carotid intimal medial thickness&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;common carotid intimal medial thickness&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004869</classIRI>
<classLabel>YKL40 measurement</classLabel>
<newAxiom>&apos;YKL40 measurement&apos; SubClassOf &apos;glycoprotein measurement&apos;</newAxiom>
<newAxiom>&apos;YKL40 measurement&apos; SubClassOf &apos;inflammatory marker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004874</classIRI>
<classLabel>memory performance</classLabel>
<deletedAxiom>&apos;memory performance&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;memory performance&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005527</classIRI>
<classLabel>ejection fraction measurement</classLabel>
<deletedAxiom>&apos;ejection fraction measurement&apos; SubClassOf &apos;cardiovascular measurement&apos;</deletedAxiom>
<newAxiom>&apos;ejection fraction measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005528</classIRI>
<classLabel>parasitemia measurement</classLabel>
<deletedAxiom>&apos;parasitemia measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;parasitemia measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006843</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005514</classIRI>
<classLabel>HER2 status</classLabel>
<deletedAxiom>&apos;HER2 status&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;HER2 status&apos; SubClassOf &apos;cancer biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004468</classIRI>
<classLabel>glucose measurement</classLabel>
<deletedAxiom>&apos;glucose measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;glucose measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006842</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004467</classIRI>
<classLabel>insulin measurement</classLabel>
<newAxiom>&apos;insulin measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006842</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005512</classIRI>
<classLabel>estrogen receptor status</classLabel>
<deletedAxiom>&apos;estrogen receptor status&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;estrogen receptor status&apos; SubClassOf &apos;cancer biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005513</classIRI>
<classLabel>progesterone receptor status</classLabel>
<deletedAxiom>&apos;progesterone receptor status&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;progesterone receptor status&apos; SubClassOf &apos;cancer biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004459</classIRI>
<classLabel>ferritin measurement</classLabel>
<deletedAxiom>&apos;ferritin measurement&apos; SubClassOf &apos;iron biomarker measurement&apos;</deletedAxiom>
<newAxiom>&apos;ferritin measurement&apos; SubClassOf &apos;measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005576</classIRI>
<classLabel>pernicious anemia</classLabel>
<deletedAxiom>&apos;pernicious anemia&apos; SubClassOf &apos;vitamin deficiency&apos;</deletedAxiom>
<newAxiom>&apos;pernicious anemia&apos; SubClassOf &apos;nutritional disorder&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005530</classIRI>
<classLabel>Trypanosoma cruzi seropositivity</classLabel>
<deletedAxiom>&apos;Trypanosoma cruzi seropositivity&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;Trypanosoma cruzi seropositivity&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006843</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_50683</classIRI>
<classLabel>folic acid reductase inhibitor</classLabel>
<newAxiom>&apos;folic acid reductase inhibitor&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004575</classIRI>
<classLabel>e-selectin measurement</classLabel>
<newAxiom>&apos;e-selectin measurement&apos; SubClassOf &apos;cancer biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004578</classIRI>
<classLabel>homocysteine measurement</classLabel>
<newAxiom>&apos;homocysteine measurement&apos; SubClassOf &apos;amino acid measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004579</classIRI>
<classLabel>serum IgE measurement</classLabel>
<newAxiom>&apos;serum IgE measurement&apos; SubClassOf &apos;eosinophil count&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004570</classIRI>
<classLabel>bilirubin measurement</classLabel>
<deletedAxiom>&apos;bilirubin measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;bilirubin measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006845</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004572</classIRI>
<classLabel>C4BP measurement</classLabel>
<newAxiom>&apos;C4BP measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004573</classIRI>
<classLabel>chemerin measurement</classLabel>
<newAxiom>&apos;chemerin measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004569</classIRI>
<classLabel>brain serotonin transporter measurement</classLabel>
<deletedAxiom>&apos;brain serotonin transporter measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;brain serotonin transporter measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004589</classIRI>
<classLabel>brachial circumference</classLabel>
<newAxiom>&apos;brachial circumference&apos; SubClassOf &apos;muscle mass measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004587</classIRI>
<classLabel>lymphocyte count</classLabel>
<newAxiom>&apos;lymphocyte count&apos; SubClassOf &apos;cancer biomarker measurement&apos;</newAxiom>
<newAxiom>&apos;lymphocyte count&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006843</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004584</classIRI>
<classLabel>mean platelet volume</classLabel>
<newAxiom>&apos;mean platelet volume&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006846</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004515</classIRI>
<classLabel>muscle mass measurement</classLabel>
<deletedAxiom>&apos;muscle mass measurement&apos; SubClassOf &apos;bone fracture related measurement&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004510</classIRI>
<classLabel>HPV seropositivity</classLabel>
<deletedAxiom>&apos;HPV seropositivity&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;HPV seropositivity&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006843</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004517</classIRI>
<classLabel>arterial stiffness measurement</classLabel>
<deletedAxiom>&apos;arterial stiffness measurement&apos; SubClassOf &apos;cardiovascular measurement&apos;</deletedAxiom>
<newAxiom>&apos;arterial stiffness measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004507</classIRI>
<classLabel>D dimer measurement</classLabel>
<newAxiom>&apos;D dimer measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005661</classIRI>
<classLabel>Child Behaviour Checklist assessment</classLabel>
<deletedAxiom>&apos;Child Behaviour Checklist assessment&apos; SubClassOf &apos;behavior or behavioral disorder measurement&apos;</deletedAxiom>
<newAxiom>&apos;Child Behaviour Checklist assessment&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005660</classIRI>
<classLabel>plasma beta-amyloid 1-42 measurement</classLabel>
<deletedAxiom>&apos;plasma beta-amyloid 1-42 measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;plasma beta-amyloid 1-42 measurement&apos; SubClassOf &apos;Alzheimer&apos;s disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004533</classIRI>
<classLabel>alkaline phosphatase measurement</classLabel>
<newAxiom>&apos;alkaline phosphatase measurement&apos; SubClassOf &apos;bone measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004534</classIRI>
<classLabel>creatine kinase measurement</classLabel>
<deletedAxiom>&apos;creatine kinase measurement&apos; SubClassOf &apos;renal system measurement&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004535</classIRI>
<classLabel>serum albumin measurement</classLabel>
<newAxiom>&apos;serum albumin measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006845</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005659</classIRI>
<classLabel>plasma beta-amyloid 1-40 measurement</classLabel>
<deletedAxiom>&apos;plasma beta-amyloid 1-40 measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;plasma beta-amyloid 1-40 measurement&apos; SubClassOf &apos;Alzheimer&apos;s disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004550</classIRI>
<classLabel>amygdala reactivity measurement</classLabel>
<deletedAxiom>&apos;amygdala reactivity measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;amygdala reactivity measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005689</classIRI>
<classLabel>non-high density lipoprotein cholesterol measurement</classLabel>
<newAxiom>&apos;non-high density lipoprotein cholesterol measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005671</classIRI>
<classLabel>smoking behaviour measurement</classLabel>
<deletedAxiom>&apos;smoking behaviour measurement&apos; SubClassOf &apos;behavior or behavioral disorder measurement&apos;</deletedAxiom>
<newAxiom>&apos;smoking behaviour measurement&apos; SubClassOf &apos;measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006793</classIRI>
<classLabel>left inferior lateral ventricle volume measurement</classLabel>
<newAxiom>&apos;left inferior lateral ventricle volume measurement&apos; SubClassOf &apos;Alzheimer&apos;s disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006798</classIRI>
<classLabel>neuritic plaque measurement</classLabel>
<deletedAxiom>&apos;neuritic plaque measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;neuritic plaque measurement&apos; SubClassOf &apos;Alzheimer&apos;s disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004269</classIRI>
<classLabel>cardiac arrhythmia</classLabel>
<deletedAxiom>&apos;cardiac arrhythmia&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005761</classIRI>
<classLabel>lupus nephritis</classLabel>
<newAxiom>&apos;lupus nephritis&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006846</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004237</classIRI>
<classLabel>Graves disease</classLabel>
<deletedAxiom>&apos;Graves disease&apos; SubClassOf &apos;autoimmune disease&apos;</deletedAxiom>
<newAxiom>&apos;Graves disease&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006812</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005763</classIRI>
<classLabel>pulse pressure measurement</classLabel>
<deletedAxiom>&apos;pulse pressure measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;pulse pressure measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005843</classIRI>
<classLabel>cortisol measurement</classLabel>
<newAxiom>&apos;cortisol measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004326</classIRI>
<classLabel>heart rate</classLabel>
<newAxiom>&apos;heart rate&apos; SubClassOf &apos;heart function measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005850</classIRI>
<classLabel>emphysema pattern measurement</classLabel>
<deletedAxiom>&apos;emphysema pattern measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;emphysema pattern measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006841</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005878</classIRI>
<classLabel>vitamin deficiency</classLabel>
<deletedAxiom>&apos;vitamin deficiency&apos; SubClassOf &apos;nutritional disorder&apos;</deletedAxiom>
<newAxiom>&apos;vitamin deficiency&apos; SubClassOf http://purl.obolibrary.org/obo/HP_0100508</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005890</classIRI>
<classLabel>osteoarthritis biomarker measurement</classLabel>
<deletedAxiom>&apos;osteoarthritis biomarker measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;osteoarthritis biomarker measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006846</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004313</classIRI>
<classLabel>maximal midexpiratory flow rate</classLabel>
<newAxiom>&apos;maximal midexpiratory flow rate&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006841</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004314</classIRI>
<classLabel>forced expiratory volume</classLabel>
<newAxiom>&apos;forced expiratory volume&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006841</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004311</classIRI>
<classLabel>heart function measurement</classLabel>
<deletedAxiom>&apos;heart function measurement&apos; SubClassOf &apos;cardiovascular measurement&apos;</deletedAxiom>
<newAxiom>&apos;heart function measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004304</classIRI>
<classLabel>blood sedimentation</classLabel>
<newAxiom>&apos;blood sedimentation&apos; SubClassOf &apos;inflammatory marker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0004301</classIRI>
<classLabel>blood viscosity</classLabel>
<newAxiom>&apos;blood viscosity&apos; SubClassOf &apos;inflammatory marker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006501</classIRI>
<classLabel>carotid plaque build</classLabel>
<deletedAxiom>&apos;carotid plaque build&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;carotid plaque build&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006506</classIRI>
<classLabel>hepatic lipid content measurement</classLabel>
<deletedAxiom>&apos;hepatic lipid content measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;hepatic lipid content measurement&apos; SubClassOf &apos;lipid measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006512</classIRI>
<classLabel>angiographic measurement</classLabel>
<deletedAxiom>&apos;angiographic measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;angiographic measurement&apos; SubClassOf &apos;cardiovascular measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006515</classIRI>
<classLabel>angiotensin-converting enzyme measurement</classLabel>
<deletedAxiom>&apos;angiotensin-converting enzyme measurement&apos; SubClassOf &apos;Alzheimer&apos;s disease biomarker measurement&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005918</classIRI>
<classLabel>osteoprotegerin measurement</classLabel>
<deletedAxiom>&apos;osteoprotegerin measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;osteoprotegerin measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006524</classIRI>
<classLabel>L-arginine measurement</classLabel>
<deletedAxiom>&apos;L-arginine measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;L-arginine measurement&apos; SubClassOf &apos;amino acid measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006521</classIRI>
<classLabel>calcium intake measurement</classLabel>
<deletedAxiom>&apos;calcium intake measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;calcium intake measurement&apos; SubClassOf &apos;calcium measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005921</classIRI>
<classLabel>FEV change measurement</classLabel>
<newAxiom>&apos;FEV change measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006841</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005126</classIRI>
<classLabel>arylesterase enzyme measurement</classLabel>
<deletedAxiom>&apos;arylesterase enzyme measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;arylesterase enzyme measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005128</classIRI>
<classLabel>albumin:globulin ratio measurement</classLabel>
<newAxiom>&apos;albumin:globulin ratio measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006845</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005194</classIRI>
<classLabel>amyloid-beta measurement</classLabel>
<newAxiom>&apos;amyloid-beta measurement&apos; SubClassOf &apos;Alzheimer&apos;s disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005199</classIRI>
<classLabel>renal transplant outcome measurement</classLabel>
<deletedAxiom>&apos;renal transplant outcome measurement&apos; SubClassOf &apos;renal system measurement&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005189</classIRI>
<classLabel>respiratory quotient</classLabel>
<deletedAxiom>&apos;respiratory quotient&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;respiratory quotient&apos; SubClassOf &apos;metabolic rate measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005188</classIRI>
<classLabel>CCL11 measurement</classLabel>
<deletedAxiom>&apos;CCL11 measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;CCL11 measurement&apos; SubClassOf &apos;cytokine measurement&apos;</newAxiom>
<newAxiom>&apos;CCL11 measurement&apos; SubClassOf &apos;inflammatory marker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005187</classIRI>
<classLabel>C-peptide measurement</classLabel>
<deletedAxiom>&apos;C-peptide measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;C-peptide measurement&apos; SubClassOf &apos;cancer biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005132</classIRI>
<classLabel>5-HIAA measurement</classLabel>
<deletedAxiom>&apos;5-HIAA measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;5-HIAA measurement&apos; SubClassOf &apos;cancer biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005133</classIRI>
<classLabel>MHPG measurement</classLabel>
<deletedAxiom>&apos;MHPG measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;MHPG measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005131</classIRI>
<classLabel>HVA measurement</classLabel>
<deletedAxiom>&apos;HVA measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;HVA measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005243</classIRI>
<classLabel>myeloperoxidase measurement</classLabel>
<deletedAxiom>&apos;myeloperoxidase measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;myeloperoxidase measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005200</classIRI>
<classLabel>antiphospholipid antibody measurement</classLabel>
<newAxiom>&apos;antiphospholipid antibody measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006846</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005298</classIRI>
<classLabel>allergic sensitization measurement</classLabel>
<deletedAxiom>&apos;allergic sensitization measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;allergic sensitization measurement&apos; SubClassOf &apos;eosinophil count&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005303</classIRI>
<classLabel>sudden infant death syndrome</classLabel>
<deletedAxiom>&apos;sudden infant death syndrome&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_50469</classIRI>
<classLabel>phospholipase A2 inhibitor</classLabel>
<newAxiom>&apos;phospholipase A2 inhibitor&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_24852</classIRI>
<classLabel>insecticide</classLabel>
<newAxiom>&apos;insecticide&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006803</classIRI>
<classLabel>vasculitis</classLabel>
<deletedAxiom>&apos;vasculitis&apos; SubClassOf &apos;material entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006800</classIRI>
<classLabel>vascular brain injury measurement</classLabel>
<deletedAxiom>&apos;vascular brain injury measurement&apos; SubClassOf &apos;cardiovascular measurement&apos;</deletedAxiom>
<newAxiom>&apos;vascular brain injury measurement&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005413</classIRI>
<classLabel>joint damage measurement</classLabel>
<deletedAxiom>&apos;joint damage measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;joint damage measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006846</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005412</classIRI>
<classLabel>functional impairment measurement</classLabel>
<deletedAxiom>&apos;functional impairment measurement&apos; SubClassOf &apos;behavior or behavioral disorder measurement&apos;</deletedAxiom>
<newAxiom>&apos;functional impairment measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005415</classIRI>
<classLabel>serum alpha-1-antitrypsin measurement</classLabel>
<deletedAxiom>&apos;serum alpha-1-antitrypsin measurement&apos; SubClassOf &apos;protein measurement&apos;</deletedAxiom>
<newAxiom>&apos;serum alpha-1-antitrypsin measurement&apos; SubClassOf &apos;alpha globulin measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005420</classIRI>
<classLabel>grey matter volume measurement</classLabel>
<newAxiom>&apos;grey matter volume measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_35703</classIRI>
<classLabel>xenobiotic</classLabel>
<newAxiom>&apos;xenobiotic&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_35705</classIRI>
<classLabel>immunosuppressive agent</classLabel>
<newAxiom>&apos;immunosuppressive agent&apos; SubClassOf &apos;chemical role&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005035</classIRI>
<classLabel>hippocampal volume</classLabel>
<newAxiom>&apos;hippocampal volume&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005037</classIRI>
<classLabel>aortic root size</classLabel>
<deletedAxiom>&apos;aortic root size&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;aortic root size&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005043</classIRI>
<classLabel>cardiac troponin T measurement</classLabel>
<deletedAxiom>&apos;cardiac troponin T measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;cardiac troponin T measurement&apos; SubClassOf &apos;heart function measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005080</classIRI>
<classLabel>CC16 measurement</classLabel>
<deletedAxiom>&apos;CC16 measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;CC16 measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006841</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005090</classIRI>
<classLabel>basophil count</classLabel>
<newAxiom>&apos;basophil count&apos; SubClassOf &apos;inflammatory marker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005094</classIRI>
<classLabel>P wave duration</classLabel>
<deletedAxiom>&apos;P wave duration&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;P wave duration&apos; SubClassOf &apos;cardiovascular measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005093</classIRI>
<classLabel>hip circumference</classLabel>
<newAxiom>&apos;hip circumference&apos; SubClassOf &apos;bone measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005053</classIRI>
<classLabel>internal carotid intimal medial thickness</classLabel>
<deletedAxiom>&apos;internal carotid intimal medial thickness&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;internal carotid intimal medial thickness&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005054</classIRI>
<classLabel>QRS complex</classLabel>
<deletedAxiom>&apos;QRS complex&apos; SubClassOf &apos;cardiovascular measurement&apos;</deletedAxiom>
<newAxiom>&apos;QRS complex&apos; SubClassOf &apos;cardiovascular disease biomarker measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005095</classIRI>
<classLabel>PR segment</classLabel>
<deletedAxiom>&apos;PR segment&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;PR segment&apos; SubClassOf &apos;cardiovascular measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005002</classIRI>
<classLabel>lysine measurement</classLabel>
<deletedAxiom>&apos;lysine measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;lysine measurement&apos; SubClassOf &apos;amino acid measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0005001</classIRI>
<classLabel>phenylalanine measurement</classLabel>
<deletedAxiom>&apos;phenylalanine measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;phenylalanine measurement&apos; SubClassOf &apos;amino acid measurement&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006319</classIRI>
<classLabel>HIV viral set point measurement</classLabel>
<deletedAxiom>&apos;HIV viral set point measurement&apos; SubClassOf &apos;measurement&apos;</deletedAxiom>
<newAxiom>&apos;HIV viral set point measurement&apos; SubClassOf http://www.ebi.ac.uk/efo/EFO_0006843</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/HP_0001873</classIRI>
<classLabel>thromobocytopenia</classLabel>
<newAxiom>'thromobocytopenia' SubClassOf 'abnormality of blood and blood-forming tissues'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/HP_0100508</classIRI>
<classLabel>abnormality of vitamin metabolism</classLabel>
<newAxiom>'abnormality of vitamin metabolism' SubClassOf 'abnormality of metabolism/homeostasis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/HP_0001392</classIRI>
<classLabel>abnormality of the liver</classLabel>
<newAxiom>'abnormality of the liver' SubClassOf 'abnormality of the abdomen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006629</classIRI>
<classLabel>lipid metabolic process</classLabel>
<newAxiom>'lipid metabolic process' SubClassOf 'single-organism metabolic process'</newAxiom>
<newAxiom>'lipid metabolic process' SubClassOf 'primary metabolic process'</newAxiom>
<newAxiom>'lipid metabolic process' SubClassOf 'organic substance metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/HP_0003119</classIRI>
<classLabel>Abnormality of lipid metabolism</classLabel>
<newAxiom>'Abnormality of lipid metabolism' SubClassOf 'abnormality of metabolism/homeostasis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/HP_0003111</classIRI>
<classLabel>Abnormality of ion homeostasis</classLabel>
<newAxiom>'Abnormality of ion homeostasis' SubClassOf 'abnormality of metabolism/homeostasis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_27823</classIRI>
<classLabel>5-HIAA</classLabel>
<newAxiom>'5-HIAA' SubClassOf 'organic heterocyclic compound'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/HP_0012115</classIRI>
<classLabel>hepatitis</classLabel>
<newAxiom>'hepatitis' SubClassOf 'abnormality of the liver'</newAxiom>
<newAxiom>'hepatitis' SubClassOf 'Abnormality of the endocrine system'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/HP_0011031</classIRI>
<classLabel>abnormality of iron homeostasis</classLabel>
<newAxiom>'abnormality of iron homeostasis' SubClassOf 'Abnormality of ion homeostasis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/HP_0012219</classIRI>
<classLabel>erythema nodosum</classLabel>
<newAxiom>'erythema nodosum' SubClassOf 'abnormality of the skin'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_1000012</classIRI>
<classLabel>Rienhoff syndrome</classLabel>
<newAxiom>'Rienhoff syndrome' SubClassOf 'Loeys-Dietz syndrome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_1000003</classIRI>
<classLabel>Zinc deficiency</classLabel>
<newAxiom>'Zinc deficiency' SubClassOf 'Abnormality of zinc homeostasis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_24867</classIRI>
<classLabel>monoatomic ion</classLabel>
<newAxiom>'monoatomic ion' SubClassOf 'chemical compound'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006846</classIRI>
<classLabel>autoimmune disease biomarker</classLabel>
<newAxiom>'autoimmune disease biomarker' SubClassOf 'measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006845</classIRI>
<classLabel>liver disease biomarker</classLabel>
<newAxiom>'liver disease biomarker' SubClassOf 'measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006848</classIRI>
<classLabel>mental or behavioural disorder biomarker</classLabel>
<newAxiom>'mental or behavioural disorder biomarker' SubClassOf 'measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006842</classIRI>
<classLabel>diabetes mellitus biomarker</classLabel>
<newAxiom>'diabetes mellitus biomarker' SubClassOf 'measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006841</classIRI>
<classLabel>respiratory disease biomarker</classLabel>
<newAxiom>'respiratory disease biomarker' SubClassOf 'measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006843</classIRI>
<classLabel>infectious disease biomarker</classLabel>
<newAxiom>'infectious disease biomarker' SubClassOf 'measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006833</classIRI>
<classLabel>glucose effectiveness measurement</classLabel>
<newAxiom>'glucose effectiveness measurement' SubClassOf 'glucose measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006832</classIRI>
<classLabel>disposition index measurement</classLabel>
<newAxiom>'disposition index measurement' SubClassOf 'insulin measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006831</classIRI>
<classLabel>acute insulin response measurement</classLabel>
<newAxiom>'acute insulin response measurement' SubClassOf 'insulin measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006830</classIRI>
<classLabel>insulin metabolic clearance rate measurement</classLabel>
<newAxiom>'insulin metabolic clearance rate measurement' SubClassOf 'diabetes mellitus biomarker'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006836</classIRI>
<classLabel>rapid kidney function decline</classLabel>
<newAxiom>'rapid kidney function decline' SubClassOf 'phenotype'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006835</classIRI>
<classLabel>pyoderma gangrenosum</classLabel>
<newAxiom>'pyoderma gangrenosum' SubClassOf 'abnormality of the skin'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006834</classIRI>
<classLabel>septic shock</classLabel>
<newAxiom>'septic shock' SubClassOf 'sign or symptom'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006820</classIRI>
<classLabel>complicated disease course</classLabel>
<newAxiom>'complicated disease course' SubClassOf 'disease course'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006822</classIRI>
<classLabel>trans-16:1n-7 fatty acid measurement</classLabel>
<newAxiom>'trans-16:1n-7 fatty acid measurement' SubClassOf 'trans fatty acid measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006821</classIRI>
<classLabel>trans fatty acid measurement</classLabel>
<newAxiom>'trans fatty acid measurement' SubClassOf 'fatty acid measurement'</newAxiom>
<newAxiom>'trans fatty acid measurement' SubClassOf 'cardiovascular disease biomarker measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006824</classIRI>
<classLabel>cis/trans-18:2 fatty acid measurement</classLabel>
<newAxiom>'cis/trans-18:2 fatty acid measurement' SubClassOf 'trans fatty acid measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006823</classIRI>
<classLabel>total trans-18:1 fatty acid measurement</classLabel>
<newAxiom>'total trans-18:1 fatty acid measurement' SubClassOf 'trans fatty acid measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006826</classIRI>
<classLabel>trans/trans-18:2 fatty acid measurement</classLabel>
<newAxiom>'trans/trans-18:2 fatty acid measurement' SubClassOf 'trans fatty acid measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006825</classIRI>
<classLabel>trans/cis-18:2 fatty acid measurement</classLabel>
<newAxiom>'trans/cis-18:2 fatty acid measurement' SubClassOf 'trans fatty acid measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006827</classIRI>
<classLabel>renin–angiotensin–aldosterone system measurement</classLabel>
<newAxiom>'renin–angiotensin–aldosterone system measurement' SubClassOf 'cardiovascular disease biomarker measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006828</classIRI>
<classLabel>plasma renin activity measurement</classLabel>
<newAxiom>'plasma renin activity measurement' SubClassOf 'renin–angiotensin–aldosterone system measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006829</classIRI>
<classLabel>GFR change measurement</classLabel>
<newAxiom>'GFR change measurement' SubClassOf 'renal system measurement'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006814</classIRI>
<classLabel>caryopsis</classLabel>
<newAxiom>'caryopsis' SubClassOf 'plant reproductive system structure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006815</classIRI>
<classLabel>tiller</classLabel>
<newAxiom>'tiller' SubClassOf 'shoot'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006812</classIRI>
<classLabel>autoimmune thyroid disease</classLabel>
<newAxiom>'autoimmune thyroid disease' SubClassOf 'endocrine system disease'</newAxiom>
<newAxiom>'autoimmune thyroid disease' SubClassOf 'autoimmune disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006813</classIRI>
<classLabel>atrophic thyroiditis</classLabel>
<newAxiom>'atrophic thyroiditis' SubClassOf 'autoimmune thyroid disease'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006819</classIRI>
<classLabel>mild disease course</classLabel>
<newAxiom>'mild disease course' SubClassOf 'disease course'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006818</classIRI>
<classLabel>stricture</classLabel>
<newAxiom>'stricture' SubClassOf 'sign or symptom'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006817</classIRI>
<classLabel>yang deficiency</classLabel>
<newAxiom>'yang deficiency' SubClassOf 'sign or symptom'</newAxiom>
</newClass>
<newClass>
<classIRI>http://www.ebi.ac.uk/efo/EFO_0006816</classIRI>
<classLabel>response to heparin</classLabel>
<newAxiom>'response to heparin' SubClassOf 'response to anticoagulant'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/HP_0008277</classIRI>
<classLabel>Abnormality of zinc homeostasis</classLabel>
<newAxiom>'Abnormality of zinc homeostasis' SubClassOf 'Abnormality of ion homeostasis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OBI_0000427</classIRI>
<classLabel>enzyme</classLabel>
<newAxiom>'enzyme' SubClassOf 'biological role'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055069</classIRI>
<classLabel>zinc ion homeostasis</classLabel>
<newAxiom>'zinc ion homeostasis' SubClassOf 'biological process'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>